157688:FVE77 RS07070
gene id: 157688:FVE77_RS07070
uniprot id: A0A510JHI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

157688:FVE77 RS07610
gene id: 157688:FVE77_RS07610
uniprot id: A0A510JKQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

157688:FVE77 RS06640
gene id: 157688:FVE77_RS06640
uniprot id: A0A510JHD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

157688:FVE77 RS07365
gene id: 157688:FVE77_RS07365
uniprot id: A0A510JM08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

157688:FVE77 RS02900
gene id: 157688:FVE77_RS02900
uniprot id: A0A510JHM9
names: Similarity
messages: Belongs to the PspA/IM30 family.

157688:FVE77 RS07815
gene id: 157688:FVE77_RS07815
uniprot id: A0A510JI03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

157688:FVE77 RS09795
gene id: 157688:FVE77_RS09795
uniprot id: A0A510JJ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

157688:FVE77 RS07340
gene id: 157688:FVE77_RS07340
uniprot id: A0A510JHR9
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

157688:FVE77 RS00170
gene id: 157688:FVE77_RS00170
uniprot id: A0A510JDH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

157688:FVE77 RS05670
gene id: 157688:FVE77_RS05670
uniprot id: A0A510JGP5
names: Similarity
messages: Belongs to the RecJ family.

157688:FVE77 RS01045
gene id: 157688:FVE77_RS01045
uniprot id: A0A510JE07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

157688:FVE77 RS00580
gene id: 157688:FVE77_RS00580
uniprot id: A0A510JHR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS01320
gene id: 157688:FVE77_RS01320
uniprot id: A0A510JH76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

157688:FVE77 RS03930
gene id: 157688:FVE77_RS03930
uniprot id: A0A510JFR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

157688:FVE77 RS09200
gene id: 157688:FVE77_RS09200
uniprot id: A0A510JIS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

157688:FVE77 RS08710
gene id: 157688:FVE77_RS08710
uniprot id: A0A510JMW0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

157688:FVE77 RS04855
gene id: 157688:FVE77_RS04855
uniprot id: A0A510JGA1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

157688:FVE77 RS08350
gene id: 157688:FVE77_RS08350
uniprot id: A0A510JI96
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

157688:FVE77 RS02175
gene id: 157688:FVE77_RS02175
uniprot id: A0A510JES2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

157688:FVE77 RS03560
gene id: 157688:FVE77_RS03560
uniprot id: A0A510JI15
names: Similarity
messages: Belongs to the peptidase C40 family.

157688:FVE77 RS02350
gene id: 157688:FVE77_RS02350
uniprot id: A0A510JEW6
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

157688:FVE77 RS05855
gene id: 157688:FVE77_RS05855
uniprot id: A0A510JH57
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

157688:FVE77 RS11990
gene id: 157688:FVE77_RS11990
uniprot id: A0A510JKL4
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS09715
gene id: 157688:FVE77_RS09715
uniprot id: A0A510JJ24
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

157688:FVE77 RS11965
gene id: 157688:FVE77_RS11965
uniprot id: A0A510JMT3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

157688:FVE77 RS09490
gene id: 157688:FVE77_RS09490
uniprot id: A0A510JIU5
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS09430
gene id: 157688:FVE77_RS09430
uniprot id: A0A510JIY7
names: Similarity
messages: Belongs to the fabD family.

157688:FVE77 RS06430
gene id: 157688:FVE77_RS06430
uniprot id: A0A510JH86
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

157688:FVE77 RS03160
gene id: 157688:FVE77_RS03160
uniprot id: A0A510JJD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

157688:FVE77 RS10110
gene id: 157688:FVE77_RS10110
uniprot id: A0A510JJK8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

157688:FVE77 RS05390
gene id: 157688:FVE77_RS05390
uniprot id: A0A510JGJ0
names: Similarity
messages: Belongs to the MlaA family.

157688:FVE77 RS08260
gene id: 157688:FVE77_RS08260
uniprot id: A0A510JIH7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

157688:FVE77 RS07090
gene id: 157688:FVE77_RS07090
uniprot id: A0A510JHJ7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

157688:FVE77 RS03135
gene id: 157688:FVE77_RS03135
uniprot id: A0A510JFA0
names: Similarity
messages: Belongs to the EfeM/EfeO family.

157688:FVE77 RS10590
gene id: 157688:FVE77_RS10590
uniprot id: A0A510JMC0
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

157688:FVE77 RS03080
gene id: 157688:FVE77_RS03080
uniprot id: A0A510JFC3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

157688:FVE77 RS07805
gene id: 157688:FVE77_RS07805
uniprot id: A0A510JKU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

157688:FVE77 RS09180
gene id: 157688:FVE77_RS09180
uniprot id: A0A510JIZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

157688:FVE77 RS02560
gene id: 157688:FVE77_RS02560
uniprot id: A0A510JET9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

157688:FVE77 RS01575
gene id: 157688:FVE77_RS01575
uniprot id: A0A510JHC7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

157688:FVE77 RS05510
gene id: 157688:FVE77_RS05510
uniprot id: A0A510JJI2
names: Similarity
messages: Belongs to the YggT family.

157688:FVE77 RS12390
gene id: 157688:FVE77_RS12390
uniprot id: A0A510JKM3
names: Similarity
messages: Belongs to the peptidase S51 family.

157688:FVE77 RS05650
gene id: 157688:FVE77_RS05650
uniprot id: A0A510JGQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

157688:FVE77 RS07660
gene id: 157688:FVE77_RS07660
uniprot id: A0A510JKR1
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

157688:FVE77 RS10185
gene id: 157688:FVE77_RS10185
uniprot id: A0A510JJ95
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS09870
gene id: 157688:FVE77_RS09870
uniprot id: A0A510JJF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

157688:FVE77 RS11285
gene id: 157688:FVE77_RS11285
uniprot id: A0A510JMN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

157688:FVE77 RS02880
gene id: 157688:FVE77_RS02880
uniprot id: A0A510JFJ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

157688:FVE77 RS01280
gene id: 157688:FVE77_RS01280
uniprot id: A0A510JED7
names: Similarity
messages: Belongs to the thioredoxin family.

157688:FVE77 RS03210
gene id: 157688:FVE77_RS03210
uniprot id: A0A510JHT9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

157688:FVE77 RS06730
gene id: 157688:FVE77_RS06730
uniprot id: A0A510JK82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

157688:FVE77 RS08830
gene id: 157688:FVE77_RS08830
uniprot id: A0A510JIR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

157688:FVE77 RS10670
gene id: 157688:FVE77_RS10670
uniprot id: A0A510JMD2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

157688:FVE77 RS08985
gene id: 157688:FVE77_RS08985
uniprot id: A0A510JIW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS01030
gene id: 157688:FVE77_RS01030
uniprot id: A0A510JH11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

157688:FVE77 RS05085
gene id: 157688:FVE77_RS05085
uniprot id: A0A510JGE7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS11620
gene id: 157688:FVE77_RS11620
uniprot id: A0A510JK12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

157688:FVE77 RS06830
gene id: 157688:FVE77_RS06830
uniprot id: A0A510JK99
names: Similarity
messages: Belongs to the UPF0246 family.

157688:FVE77 RS09045
gene id: 157688:FVE77_RS09045
uniprot id: A0A510JIM3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS00415
gene id: 157688:FVE77_RS00415
uniprot id: A0A510JDM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

157688:FVE77 RS06460
gene id: 157688:FVE77_RS06460
uniprot id: A0A510JLE0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

157688:FVE77 RS06510
gene id: 157688:FVE77_RS06510
uniprot id: A0A510JH31
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

157688:FVE77 RS05165
gene id: 157688:FVE77_RS05165
uniprot id: A0A510JGF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

157688:FVE77 RS05850
gene id: 157688:FVE77_RS05850
uniprot id: A0A510JGU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

157688:FVE77 RS07990
gene id: 157688:FVE77_RS07990
uniprot id: A0A510JKN2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

157688:FVE77 RS02775
gene id: 157688:FVE77_RS02775
uniprot id: A0A510JEX9
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

157688:FVE77 RS05905
gene id: 157688:FVE77_RS05905
uniprot id: A0A510JH64
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS03305
gene id: 157688:FVE77_RS03305
uniprot id: A0A510JHV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

157688:FVE77 RS05185
gene id: 157688:FVE77_RS05185
uniprot id: A0A510JGF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

157688:FVE77 RS09850
gene id: 157688:FVE77_RS09850
uniprot id: A0A510JJ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

157688:FVE77 RS06845
gene id: 157688:FVE77_RS06845
uniprot id: A0A510JHE1
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

157688:FVE77 RS04410
gene id: 157688:FVE77_RS04410
uniprot id: A0A510JG40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

157688:FVE77 RS01070
gene id: 157688:FVE77_RS01070
uniprot id: A0A510JI67
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

157688:FVE77 RS09610
gene id: 157688:FVE77_RS09610
uniprot id: A0A510JIW8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

157688:FVE77 RS10230
gene id: 157688:FVE77_RS10230
uniprot id: A0A510JLW2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

157688:FVE77 RS03465
gene id: 157688:FVE77_RS03465
uniprot id: A0A510JFC0
names: Similarity
messages: Belongs to the TrbI/VirB10 family.

157688:FVE77 RS00970
gene id: 157688:FVE77_RS00970
uniprot id: A0A510JDZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS07410
gene id: 157688:FVE77_RS07410
uniprot id: A0A510JHM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

157688:FVE77 RS10430
gene id: 157688:FVE77_RS10430
uniprot id: A0A510JJE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

157688:FVE77 RS06995
gene id: 157688:FVE77_RS06995
uniprot id: A0A510JHH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

157688:FVE77 RS06930
gene id: 157688:FVE77_RS06930
uniprot id: A0A510JKB5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

157688:FVE77 RS11310
gene id: 157688:FVE77_RS11310
uniprot id: A0A510JJV4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

157688:FVE77 RS03480
gene id: 157688:FVE77_RS03480
uniprot id: A0A510JIC9
names: Similarity
messages: Belongs to the GSP E family.

157688:FVE77 RS09880
gene id: 157688:FVE77_RS09880
uniprot id: A0A510JJ30
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

157688:FVE77 RS04345
gene id: 157688:FVE77_RS04345
uniprot id: A0A510JIV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

157688:FVE77 RS06080
gene id: 157688:FVE77_RS06080
uniprot id: A0A510JGZ4
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS05445
gene id: 157688:FVE77_RS05445
uniprot id: A0A510JGG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS09235
gene id: 157688:FVE77_RS09235
uniprot id: A0A510JIU8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

157688:FVE77 RS11290
gene id: 157688:FVE77_RS11290
uniprot id: A0A510JK70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

157688:FVE77 RS03460
gene id: 157688:FVE77_RS03460
uniprot id: A0A510JHZ6
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

157688:FVE77 RS05720
gene id: 157688:FVE77_RS05720
uniprot id: A0A510JGQ7
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

157688:FVE77 RS05835
gene id: 157688:FVE77_RS05835
uniprot id: A0A510JJF3
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS02965
gene id: 157688:FVE77_RS02965
uniprot id: A0A510JF22
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

157688:FVE77 RS11265
gene id: 157688:FVE77_RS11265
uniprot id: A0A510JME7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

157688:FVE77 RS11365
gene id: 157688:FVE77_RS11365
uniprot id: A0A510JJX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

157688:FVE77 RS03960
gene id: 157688:FVE77_RS03960
uniprot id: A0A510JFU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

157688:FVE77 RS11315
gene id: 157688:FVE77_RS11315
uniprot id: A0A510JMF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

157688:FVE77 RS04405
gene id: 157688:FVE77_RS04405
uniprot id: A0A510JGC9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

157688:FVE77 RS11060
gene id: 157688:FVE77_RS11060
uniprot id: A0A510JJQ5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

157688:FVE77 RS09865
gene id: 157688:FVE77_RS09865
uniprot id: A0A510JLX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

157688:FVE77 RS11140
gene id: 157688:FVE77_RS11140
uniprot id: A0A510JMC8
names: Similarity
messages: Belongs to the UPF0758 family.

157688:FVE77 RS08105
gene id: 157688:FVE77_RS08105
uniprot id: A0A510JKZ5
names: Similarity
messages: Belongs to the YciI family.

157688:FVE77 RS05950
gene id: 157688:FVE77_RS05950
uniprot id: A0A510JH72
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

157688:FVE77 RS02790
gene id: 157688:FVE77_RS02790
uniprot id: A0A510JEY9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

157688:FVE77 RS00420
gene id: 157688:FVE77_RS00420
uniprot id: A0A510JDP0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

157688:FVE77 RS07920
gene id: 157688:FVE77_RS07920
uniprot id: A0A510JI16
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

157688:FVE77 RS06115
gene id: 157688:FVE77_RS06115
uniprot id: A0A510JJL8
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

157688:FVE77 RS09535
gene id: 157688:FVE77_RS09535
uniprot id: A0A510JJ08
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS04065
gene id: 157688:FVE77_RS04065
uniprot id: A0A510JFU0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

157688:FVE77 RS05915
gene id: 157688:FVE77_RS05915
uniprot id: A0A510JGU2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

157688:FVE77 RS03915
gene id: 157688:FVE77_RS03915
uniprot id: A0A510JFT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

157688:FVE77 RS08145
gene id: 157688:FVE77_RS08145
uniprot id: A0A510JMF5
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

157688:FVE77 RS04140
gene id: 157688:FVE77_RS04140
uniprot id: A0A510JFP3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

157688:FVE77 RS00610
gene id: 157688:FVE77_RS00610
uniprot id: A0A510JDR8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

157688:FVE77 RS05395
gene id: 157688:FVE77_RS05395
uniprot id: A0A510JGE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS10135
gene id: 157688:FVE77_RS10135
uniprot id: A0A510JJ86
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

157688:FVE77 RS02295
gene id: 157688:FVE77_RS02295
uniprot id: A0A510JEW1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

157688:FVE77 RS11000
gene id: 157688:FVE77_RS11000
uniprot id: A0A510JMI7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

157688:FVE77 RS06975
gene id: 157688:FVE77_RS06975
uniprot id: A0A510JHG4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

157688:FVE77 RS05460
gene id: 157688:FVE77_RS05460
uniprot id: A0A510JJH1
names: Similarity
messages: Belongs to the peptidase M18 family.

157688:FVE77 RS01465
gene id: 157688:FVE77_RS01465
uniprot id: A0A510JEE0
names: Similarity
messages: Belongs to the thioredoxin family.

157688:FVE77 RS09040
gene id: 157688:FVE77_RS09040
uniprot id: A0A510JIQ8
names: Similarity
messages: Belongs to the RutC family.

157688:FVE77 RS11725
gene id: 157688:FVE77_RS11725
uniprot id: A0A510JMP1
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

157688:FVE77 RS04460
gene id: 157688:FVE77_RS04460
uniprot id: A0A510JG50
names: Similarity
messages: Belongs to the peptidase S66 family.

157688:FVE77 RS11920
gene id: 157688:FVE77_RS11920
uniprot id: A0A510JMS5
names: Similarity
messages: Belongs to the EutP/PduV family.

157688:FVE77 RS02510
gene id: 157688:FVE77_RS02510
uniprot id: A0A510JES4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

157688:FVE77 RS06550
gene id: 157688:FVE77_RS06550
uniprot id: A0A510JH73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

157688:FVE77 RS00665
gene id: 157688:FVE77_RS00665
uniprot id: A0A510JDU5
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS12110
gene id: 157688:FVE77_RS12110
uniprot id: A0A510JKB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

157688:FVE77 RS03570
gene id: 157688:FVE77_RS03570
uniprot id: A0A510JJL6
names: Similarity
messages: Belongs to the type IA topoisomerase family.

157688:FVE77 RS08895
gene id: 157688:FVE77_RS08895
uniprot id: A0A510JIJ1
names: Similarity
messages: Belongs to the peptidase C40 family.

157688:FVE77 RS10200
gene id: 157688:FVE77_RS10200
uniprot id: A0A510JM45
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS03030
gene id: 157688:FVE77_RS03030
uniprot id: A0A510JFB0
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

157688:FVE77 RS11090
gene id: 157688:FVE77_RS11090
uniprot id: A0A510JJS5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

157688:FVE77 RS10570
gene id: 157688:FVE77_RS10570
uniprot id: A0A510JM35
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS06635
gene id: 157688:FVE77_RS06635
uniprot id: A0A510JHJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS12000
gene id: 157688:FVE77_RS12000
uniprot id: A0A510JK80
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

157688:FVE77 RS07210
gene id: 157688:FVE77_RS07210
uniprot id: A0A510JHI4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

157688:FVE77 RS00480
gene id: 157688:FVE77_RS00480
uniprot id: A0A510JDP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS11740
gene id: 157688:FVE77_RS11740
uniprot id: A0A510JK52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

157688:FVE77 RS11300
gene id: 157688:FVE77_RS11300
uniprot id: A0A510JJU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

157688:FVE77 RS10365
gene id: 157688:FVE77_RS10365
uniprot id: A0A510JJD0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

157688:FVE77 RS01085
gene id: 157688:FVE77_RS01085
uniprot id: A0A510JEK4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

157688:FVE77 RS01020
gene id: 157688:FVE77_RS01020
uniprot id: A0A510JI53
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS09745
gene id: 157688:FVE77_RS09745
uniprot id: A0A510JJ00
names: Similarity
messages: Belongs to the asp23 family.

157688:FVE77 RS09145
gene id: 157688:FVE77_RS09145
uniprot id: A0A510JIT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

157688:FVE77 RS02260
gene id: 157688:FVE77_RS02260
uniprot id: A0A510JEX6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

157688:FVE77 RS10540
gene id: 157688:FVE77_RS10540
uniprot id: A0A510JMB1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

157688:FVE77 RS06455
gene id: 157688:FVE77_RS06455
uniprot id: A0A510JH21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

157688:FVE77 RS11510
gene id: 157688:FVE77_RS11510
uniprot id: A0A510JMJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

157688:FVE77 RS12005
gene id: 157688:FVE77_RS12005
uniprot id: A0A510JK87
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

157688:FVE77 RS08015
gene id: 157688:FVE77_RS08015
uniprot id: A0A510JIC5
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS09000
gene id: 157688:FVE77_RS09000
uniprot id: A0A510JIJ7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

157688:FVE77 RS04515
gene id: 157688:FVE77_RS04515
uniprot id: A0A510JG60
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS02665
gene id: 157688:FVE77_RS02665
uniprot id: A0A510JFF9
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS07620
gene id: 157688:FVE77_RS07620
uniprot id: A0A510JHW3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

157688:FVE77 RS10660
gene id: 157688:FVE77_RS10660
uniprot id: A0A510JP49
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

157688:FVE77 RS08405
gene id: 157688:FVE77_RS08405
uniprot id: A0A510JL51
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS04865
gene id: 157688:FVE77_RS04865
uniprot id: A0A510JGL1
names: Similarity
messages: Belongs to the CobT family.

157688:FVE77 RS07155
gene id: 157688:FVE77_RS07155
uniprot id: A0A510JK84
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS09260
gene id: 157688:FVE77_RS09260
uniprot id: A0A510JIN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

157688:FVE77 RS09925
gene id: 157688:FVE77_RS09925
uniprot id: A0A510JJ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

157688:FVE77 RS01175
gene id: 157688:FVE77_RS01175
uniprot id: A0A510JH50
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

157688:FVE77 RS05630
gene id: 157688:FVE77_RS05630
uniprot id: A0A510JGQ4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

157688:FVE77 RS01190
gene id: 157688:FVE77_RS01190
uniprot id: A0A510JE38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

157688:FVE77 RS08055
gene id: 157688:FVE77_RS08055
uniprot id: A0A510JI31
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

157688:FVE77 RS07320
gene id: 157688:FVE77_RS07320
uniprot id: A0A510JLZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

157688:FVE77 RS06305
gene id: 157688:FVE77_RS06305
uniprot id: A0A510JJR1
names: Similarity
messages: Belongs to the UDPGP type 2 family.

157688:FVE77 RS02355
gene id: 157688:FVE77_RS02355
uniprot id: A0A510JHS9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

157688:FVE77 RS11305
gene id: 157688:FVE77_RS11305
uniprot id: A0A510JJW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

157688:FVE77 RS02310
gene id: 157688:FVE77_RS02310
uniprot id: A0A510JFA3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

157688:FVE77 RS03375
gene id: 157688:FVE77_RS03375
uniprot id: A0A510JFG1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

157688:FVE77 RS07135
gene id: 157688:FVE77_RS07135
uniprot id: A0A510JHN4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

157688:FVE77 RS11370
gene id: 157688:FVE77_RS11370
uniprot id: A0A510JPJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

157688:FVE77 RS02320
gene id: 157688:FVE77_RS02320
uniprot id: A0A510JER2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

157688:FVE77 RS07370
gene id: 157688:FVE77_RS07370
uniprot id: A0A510JHP4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

157688:FVE77 RS03455
gene id: 157688:FVE77_RS03455
uniprot id: A0A510JFG6
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS05465
gene id: 157688:FVE77_RS05465
uniprot id: A0A510JGY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

157688:FVE77 RS04640
gene id: 157688:FVE77_RS04640
uniprot id: A0A510JIP3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

157688:FVE77 RS00855
gene id: 157688:FVE77_RS00855
uniprot id: A0A510JE51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

157688:FVE77 RS09555
gene id: 157688:FVE77_RS09555
uniprot id: A0A510JLI3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

157688:FVE77 RS00510
gene id: 157688:FVE77_RS00510
uniprot id: A0A510JDP9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

157688:FVE77 RS09590
gene id: 157688:FVE77_RS09590
uniprot id: A0A510JIX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

157688:FVE77 RS02470
gene id: 157688:FVE77_RS02470
uniprot id: A0A510JEY2
names: Similarity
messages: Belongs to the glutamine synthetase family.

157688:FVE77 RS04735
gene id: 157688:FVE77_RS04735
uniprot id: A0A510JG79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

157688:FVE77 RS11075
gene id: 157688:FVE77_RS11075
uniprot id: A0A510JMB8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

157688:FVE77 RS01340
gene id: 157688:FVE77_RS01340
uniprot id: A0A510JE55
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

157688:FVE77 RS09665
gene id: 157688:FVE77_RS09665
uniprot id: A0A510JNF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

157688:FVE77 RS10495
gene id: 157688:FVE77_RS10495
uniprot id: A0A510JM98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS06275
gene id: 157688:FVE77_RS06275
uniprot id: A0A510JJY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

157688:FVE77 RS06775
gene id: 157688:FVE77_RS06775
uniprot id: A0A510JHC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

157688:FVE77 RS08785
gene id: 157688:FVE77_RS08785
uniprot id: A0A510JIK7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

157688:FVE77 RS01355
gene id: 157688:FVE77_RS01355
uniprot id: A0A510JE53
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS05295
gene id: 157688:FVE77_RS05295
uniprot id: A0A510JGC2
names: Similarity
messages: Belongs to the UPF0102 family.

157688:FVE77 RS00850
gene id: 157688:FVE77_RS00850
uniprot id: A0A510JEG2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS06380
gene id: 157688:FVE77_RS06380
uniprot id: A0A510JH75
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

157688:FVE77 RS07325
gene id: 157688:FVE77_RS07325
uniprot id: A0A510JHN2
names: Similarity
messages: Belongs to the DprA/Smf family.

157688:FVE77 RS05005
gene id: 157688:FVE77_RS05005
uniprot id: A0A510JGC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

157688:FVE77 RS00825
gene id: 157688:FVE77_RS00825
uniprot id: A0A510JDV9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

157688:FVE77 RS07755
gene id: 157688:FVE77_RS07755
uniprot id: A0A510JKT0
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

157688:FVE77 RS11430
gene id: 157688:FVE77_RS11430
uniprot id: A0A510JMR3
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS03355
gene id: 157688:FVE77_RS03355
uniprot id: A0A510JHX1
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

157688:FVE77 RS06765
gene id: 157688:FVE77_RS06765
uniprot id: A0A510JH84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

157688:FVE77 RS05620
gene id: 157688:FVE77_RS05620
uniprot id: A0A510JGN6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

157688:FVE77 RS06390
gene id: 157688:FVE77_RS06390
uniprot id: A0A510JH25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

157688:FVE77 RS01405
gene id: 157688:FVE77_RS01405
uniprot id: A0A510JE64
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

157688:FVE77 RS08100
gene id: 157688:FVE77_RS08100
uniprot id: A0A510JI43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

157688:FVE77 RS02830
gene id: 157688:FVE77_RS02830
uniprot id: A0A510JF59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS02680
gene id: 157688:FVE77_RS02680
uniprot id: A0A510JEW0
names: Similarity
messages: Belongs to the YciI family.

157688:FVE77 RS08885
gene id: 157688:FVE77_RS08885
uniprot id: A0A510JIS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS06705
gene id: 157688:FVE77_RS06705
uniprot id: A0A510JH85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

157688:FVE77 RS02370
gene id: 157688:FVE77_RS02370
uniprot id: A0A510JER5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

157688:FVE77 RS08115
gene id: 157688:FVE77_RS08115
uniprot id: A0A510JI62
names: Similarity
messages: Belongs to the SAICAR synthetase family.

157688:FVE77 RS11460
gene id: 157688:FVE77_RS11460
uniprot id: A0A510JMI5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

157688:FVE77 RS04480
gene id: 157688:FVE77_RS04480
uniprot id: A0A510JG30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

157688:FVE77 RS04715
gene id: 157688:FVE77_RS04715
uniprot id: A0A510JGI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

157688:FVE77 RS08795
gene id: 157688:FVE77_RS08795
uniprot id: A0A510JIF4
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS09195
gene id: 157688:FVE77_RS09195
uniprot id: A0A510JIM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

157688:FVE77 RS04795
gene id: 157688:FVE77_RS04795
uniprot id: A0A510JKD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

157688:FVE77 RS00525
gene id: 157688:FVE77_RS00525
uniprot id: A0A510JDQ3
names: Similarity
messages: Belongs to the peptidase S41A family.

157688:FVE77 RS09165
gene id: 157688:FVE77_RS09165
uniprot id: A0A510JN50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

157688:FVE77 RS07895
gene id: 157688:FVE77_RS07895
uniprot id: A0A510JMA9
names: Similarity
messages: Belongs to the GARS family.

157688:FVE77 RS11100
gene id: 157688:FVE77_RS11100
uniprot id: A0A510JK46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS12075
gene id: 157688:FVE77_RS12075
uniprot id: A0A510JKA5
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS12080
gene id: 157688:FVE77_RS12080
uniprot id: A0A510JPZ1
names: Subcellular Location Annotation
messages: Cytoplasm

157688:FVE77 RS07005
gene id: 157688:FVE77_RS07005
uniprot id: A0A510JHF9
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS05820
gene id: 157688:FVE77_RS05820
uniprot id: A0A510JGS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

157688:FVE77 RS09910
gene id: 157688:FVE77_RS09910
uniprot id: A0A510JLZ2
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

157688:FVE77 RS08770
gene id: 157688:FVE77_RS08770
uniprot id: A0A510JII2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

157688:FVE77 RS01015
gene id: 157688:FVE77_RS01015
uniprot id: A0A510JDY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

157688:FVE77 RS11330
gene id: 157688:FVE77_RS11330
uniprot id: A0A510JJX0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

157688:FVE77 RS07045
gene id: 157688:FVE77_RS07045
uniprot id: A0A510JHI0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

157688:FVE77 RS10735
gene id: 157688:FVE77_RS10735
uniprot id: A0A510JJL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

157688:FVE77 RS09240
gene id: 157688:FVE77_RS09240
uniprot id: A0A510JIQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

157688:FVE77 RS09815
gene id: 157688:FVE77_RS09815
uniprot id: A0A510JNI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

157688:FVE77 RS07725
gene id: 157688:FVE77_RS07725
uniprot id: A0A510JHT3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

157688:FVE77 RS10720
gene id: 157688:FVE77_RS10720
uniprot id: A0A510JME0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class B bacterial acid phosphatase family.
messages: Homotetramer.
messages: Periplasm

157688:FVE77 RS11450
gene id: 157688:FVE77_RS11450
uniprot id: A0A510JJZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

157688:FVE77 RS10825
gene id: 157688:FVE77_RS10825
uniprot id: A0A510JJR0
names: Similarity
messages: Belongs to the leucine-binding protein family.

157688:FVE77 RS06025
gene id: 157688:FVE77_RS06025
uniprot id: A0A510JJJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

157688:FVE77 RS05040
gene id: 157688:FVE77_RS05040
uniprot id: A0A510JIZ8
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

157688:FVE77 RS07955
gene id: 157688:FVE77_RS07955
uniprot id: A0A510JI12
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

157688:FVE77 RS00810
gene id: 157688:FVE77_RS00810
uniprot id: A0A510JDV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

157688:FVE77 RS02875
gene id: 157688:FVE77_RS02875
uniprot id: A0A510JI18
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

157688:FVE77 RS01570
gene id: 157688:FVE77_RS01570
uniprot id: A0A510JEF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

157688:FVE77 RS00040
gene id: 157688:FVE77_RS00040
uniprot id: A0A510JHD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MnmG family.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

157688:FVE77 RS00805
gene id: 157688:FVE77_RS00805
uniprot id: A0A510JDW8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS05690
gene id: 157688:FVE77_RS05690
uniprot id: A0A510JGL2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

157688:FVE77 RS01205
gene id: 157688:FVE77_RS01205
uniprot id: A0A510JGP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

157688:FVE77 RS00715
gene id: 157688:FVE77_RS00715
uniprot id: A0A510JDV5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

157688:FVE77 RS04245
gene id: 157688:FVE77_RS04245
uniprot id: A0A510JK11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

157688:FVE77 RS12400
gene id: 157688:FVE77_RS12400
uniprot id: A0A510JKG6
names: Similarity
messages: Belongs to the Gram-positive plasmids replication protein type 1 family.

157688:FVE77 RS11755
gene id: 157688:FVE77_RS11755
uniprot id: A0A510JK77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

157688:FVE77 RS02405
gene id: 157688:FVE77_RS02405
uniprot id: A0A510JEX5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

157688:FVE77 RS10625
gene id: 157688:FVE77_RS10625
uniprot id: A0A510JJU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

157688:FVE77 RS05430
gene id: 157688:FVE77_RS05430
uniprot id: A0A510JGF1
names: Similarity
messages: Belongs to the aspartokinase family.

157688:FVE77 RS10035
gene id: 157688:FVE77_RS10035
uniprot id: A0A510JLS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

157688:FVE77 RS10400
gene id: 157688:FVE77_RS10400
uniprot id: A0A510JM78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS10080
gene id: 157688:FVE77_RS10080
uniprot id: A0A510JJ72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

157688:FVE77 RS07750
gene id: 157688:FVE77_RS07750
uniprot id: A0A510JHW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

157688:FVE77 RS09210
gene id: 157688:FVE77_RS09210
uniprot id: A0A510JIM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

157688:FVE77 RS03900
gene id: 157688:FVE77_RS03900
uniprot id: A0A510JJT8
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

157688:FVE77 RS10455
gene id: 157688:FVE77_RS10455
uniprot id: A0A510JJJ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

157688:FVE77 RS10010
gene id: 157688:FVE77_RS10010
uniprot id: A0A510JJI8
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS02325
gene id: 157688:FVE77_RS02325
uniprot id: A0A510JEP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

157688:FVE77 RS10640
gene id: 157688:FVE77_RS10640
uniprot id: A0A510JJJ0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

157688:FVE77 RS09860
gene id: 157688:FVE77_RS09860
uniprot id: A0A510JNJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

157688:FVE77 RS04495
gene id: 157688:FVE77_RS04495
uniprot id: A0A510JK67
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

157688:FVE77 RS02415
gene id: 157688:FVE77_RS02415
uniprot id: A0A510JFC1
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS05345
gene id: 157688:FVE77_RS05345
uniprot id: A0A510JGD4
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS04025
gene id: 157688:FVE77_RS04025
uniprot id: A0A510JFT8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

157688:FVE77 RS11655
gene id: 157688:FVE77_RS11655
uniprot id: A0A510JKE2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

157688:FVE77 RS10815
gene id: 157688:FVE77_RS10815
uniprot id: A0A510JMG1
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS11260
gene id: 157688:FVE77_RS11260
uniprot id: A0A510JJU4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

157688:FVE77 RS07775
gene id: 157688:FVE77_RS07775
uniprot id: A0A510JHU1
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

157688:FVE77 RS04225
gene id: 157688:FVE77_RS04225
uniprot id: A0A510JFR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

157688:FVE77 RS11320
gene id: 157688:FVE77_RS11320
uniprot id: A0A510JJV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

157688:FVE77 RS00365
gene id: 157688:FVE77_RS00365
uniprot id: A0A510JDL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

157688:FVE77 RS00575
gene id: 157688:FVE77_RS00575
uniprot id: A0A510JDR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS02475
gene id: 157688:FVE77_RS02475
uniprot id: A0A510JHU5
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS08950
gene id: 157688:FVE77_RS08950
uniprot id: A0A510JII1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

157688:FVE77 RS11160
gene id: 157688:FVE77_RS11160
uniprot id: A0A510JML8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

157688:FVE77 RS06770
gene id: 157688:FVE77_RS06770
uniprot id: A0A510JLM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

157688:FVE77 RS09015
gene id: 157688:FVE77_RS09015
uniprot id: A0A510JII4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

157688:FVE77 RS08125
gene id: 157688:FVE77_RS08125
uniprot id: A0A510JI19
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

157688:FVE77 RS09905
gene id: 157688:FVE77_RS09905
uniprot id: A0A510JJ67
names: Similarity
messages: Belongs to the RecJ family.

157688:FVE77 RS08935
gene id: 157688:FVE77_RS08935
uniprot id: A0A510JIU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

157688:FVE77 RS08185
gene id: 157688:FVE77_RS08185
uniprot id: A0A510JKS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

157688:FVE77 RS00020
gene id: 157688:FVE77_RS00020
uniprot id: A0A510JDD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

157688:FVE77 RS07515
gene id: 157688:FVE77_RS07515
uniprot id: A0A510JI17
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

157688:FVE77 RS07360
gene id: 157688:FVE77_RS07360
uniprot id: A0A510JHL8
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

157688:FVE77 RS07230
gene id: 157688:FVE77_RS07230
uniprot id: A0A510JKI9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

157688:FVE77 RS02780
gene id: 157688:FVE77_RS02780
uniprot id: A0A510JF27
names: Similarity
messages: Belongs to the peptidase S11 family.

157688:FVE77 RS05865
gene id: 157688:FVE77_RS05865
uniprot id: A0A510JH57
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

157688:FVE77 RS04740
gene id: 157688:FVE77_RS04740
uniprot id: A0A510JIT0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

157688:FVE77 RS01170
gene id: 157688:FVE77_RS01170
uniprot id: A0A510JE88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

157688:FVE77 RS08865
gene id: 157688:FVE77_RS08865
uniprot id: A0A510JIF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

157688:FVE77 RS10220
gene id: 157688:FVE77_RS10220
uniprot id: A0A510JJA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

157688:FVE77 RS01065
gene id: 157688:FVE77_RS01065
uniprot id: A0A510JDZ0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

157688:FVE77 RS06035
gene id: 157688:FVE77_RS06035
uniprot id: A0A510JGY6
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

157688:FVE77 RS05725
gene id: 157688:FVE77_RS05725
uniprot id: A0A510JGM1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

157688:FVE77 RS03990
gene id: 157688:FVE77_RS03990
uniprot id: A0A510JJW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

157688:FVE77 RS02265
gene id: 157688:FVE77_RS02265
uniprot id: A0A510JEP9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

157688:FVE77 RS03470
gene id: 157688:FVE77_RS03470
uniprot id: A0A510JJJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

157688:FVE77 RS09875
gene id: 157688:FVE77_RS09875
uniprot id: A0A510JJ74
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

157688:FVE77 RS09620
gene id: 157688:FVE77_RS09620
uniprot id: A0A510JJ01
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

157688:FVE77 RS09985
gene id: 157688:FVE77_RS09985
uniprot id: A0A510JLS1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

157688:FVE77 RS10475
gene id: 157688:FVE77_RS10475
uniprot id: A0A510JM12
names: Similarity
messages: Belongs to the DtxR/MntR family.

157688:FVE77 RS11045
gene id: 157688:FVE77_RS11045
uniprot id: A0A510JMJ5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

157688:FVE77 RS10970
gene id: 157688:FVE77_RS10970
uniprot id: A0A510JJP9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS02600
gene id: 157688:FVE77_RS02600
uniprot id: A0A510JEU6
names: Similarity
messages: Belongs to the peptidase S49 family.

157688:FVE77 RS05545
gene id: 157688:FVE77_RS05545
uniprot id: A0A510JKT5
names: Similarity
messages: Belongs to the citrate synthase family.

157688:FVE77 RS07875
gene id: 157688:FVE77_RS07875
uniprot id: A0A510JHW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

157688:FVE77 RS04725
gene id: 157688:FVE77_RS04725
uniprot id: A0A510JG64
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

157688:FVE77 RS05500
gene id: 157688:FVE77_RS05500
uniprot id: A0A510JKS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

157688:FVE77 RS03005
gene id: 157688:FVE77_RS03005
uniprot id: A0A510JF35
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

157688:FVE77 RS02125
gene id: 157688:FVE77_RS02125
uniprot id: A0A510JEQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

157688:FVE77 RS06795
gene id: 157688:FVE77_RS06795
uniprot id: A0A510JHD1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

157688:FVE77 RS11105
gene id: 157688:FVE77_RS11105
uniprot id: A0A510JJW4
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

157688:FVE77 RS03855
gene id: 157688:FVE77_RS03855
uniprot id: A0A510JJS8
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

157688:FVE77 RS07085
gene id: 157688:FVE77_RS07085
uniprot id: A0A510JHM3
names: Similarity
messages: Belongs to the aspartokinase family.

157688:FVE77 RS04615
gene id: 157688:FVE77_RS04615
uniprot id: A0A510JG78
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

157688:FVE77 RS06990
gene id: 157688:FVE77_RS06990
uniprot id: A0A510JHK0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

157688:FVE77 RS07600
gene id: 157688:FVE77_RS07600
uniprot id: A0A510JM58
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

157688:FVE77 RS11850
gene id: 157688:FVE77_RS11850
uniprot id: A0A510JK97
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

157688:FVE77 RS06860
gene id: 157688:FVE77_RS06860
uniprot id: A0A510JK13
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

157688:FVE77 RS00960
gene id: 157688:FVE77_RS00960
uniprot id: A0A510JH01
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

157688:FVE77 RS09185
gene id: 157688:FVE77_RS09185
uniprot id: A0A510JIU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

157688:FVE77 RS01295
gene id: 157688:FVE77_RS01295
uniprot id: A0A510JE59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

157688:FVE77 RS07630
gene id: 157688:FVE77_RS07630
uniprot id: A0A510JHR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS11250
gene id: 157688:FVE77_RS11250
uniprot id: A0A510JJT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

157688:FVE77 RS13030
gene id: 157688:FVE77_RS13030
uniprot id: A0A510JK72
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

157688:FVE77 RS10195
gene id: 157688:FVE77_RS10195
uniprot id: A0A510JJC3
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS06360
gene id: 157688:FVE77_RS06360
uniprot id: A0A510JLC7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

157688:FVE77 RS09625
gene id: 157688:FVE77_RS09625
uniprot id: A0A510JLT0
names: Similarity
messages: Belongs to the aldolase LacD family.

157688:FVE77 RS02065
gene id: 157688:FVE77_RS02065
uniprot id: A0A510JEL2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

157688:FVE77 RS05100
gene id: 157688:FVE77_RS05100
uniprot id: A0A510JKJ1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

157688:FVE77 RS03255
gene id: 157688:FVE77_RS03255
uniprot id: A0A510JHV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS06835
gene id: 157688:FVE77_RS06835
uniprot id: A0A510JHN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

157688:FVE77 RS07010
gene id: 157688:FVE77_RS07010
uniprot id: A0A510JK41
names: Similarity
messages: Belongs to the peptidase S1C family.

157688:FVE77 RS00500
gene id: 157688:FVE77_RS00500
uniprot id: A0A510JDY3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

157688:FVE77 RS09920
gene id: 157688:FVE77_RS09920
uniprot id: A0A510JJ44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

157688:FVE77 RS02505
gene id: 157688:FVE77_RS02505
uniprot id: A0A510JHE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

157688:FVE77 RS06150
gene id: 157688:FVE77_RS06150
uniprot id: A0A510JGW4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

157688:FVE77 RS04110
gene id: 157688:FVE77_RS04110
uniprot id: A0A510JG62
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

157688:FVE77 RS07870
gene id: 157688:FVE77_RS07870
uniprot id: A0A510JI08
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

157688:FVE77 RS11480
gene id: 157688:FVE77_RS11480
uniprot id: A0A510JMS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

157688:FVE77 RS07100
gene id: 157688:FVE77_RS07100
uniprot id: A0A510JHI3
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

157688:FVE77 RS03920
gene id: 157688:FVE77_RS03920
uniprot id: A0A510JFQ8
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS11280
gene id: 157688:FVE77_RS11280
uniprot id: A0A510JJV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

157688:FVE77 RS11255
gene id: 157688:FVE77_RS11255
uniprot id: A0A510JJV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

157688:FVE77 RS05925
gene id: 157688:FVE77_RS05925
uniprot id: A0A510JJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

157688:FVE77 RS00310
gene id: 157688:FVE77_RS00310
uniprot id: A0A510JDU3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

157688:FVE77 RS00930
gene id: 157688:FVE77_RS00930
uniprot id: A0A510JDX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

157688:FVE77 RS11490
gene id: 157688:FVE77_RS11490
uniprot id: A0A510JK28
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS09135
gene id: 157688:FVE77_RS09135
uniprot id: A0A510JLI0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

157688:FVE77 RS01195
gene id: 157688:FVE77_RS01195
uniprot id: A0A510JE24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

157688:FVE77 RS06745
gene id: 157688:FVE77_RS06745
uniprot id: A0A510JHC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

157688:FVE77 RS01035
gene id: 157688:FVE77_RS01035
uniprot id: A0A510JEJ8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

157688:FVE77 RS08270
gene id: 157688:FVE77_RS08270
uniprot id: A0A510JI76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

157688:FVE77 RS00655
gene id: 157688:FVE77_RS00655
uniprot id: A0A510JDU1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

157688:FVE77 RS09635
gene id: 157688:FVE77_RS09635
uniprot id: A0A510JJ26
names: Similarity
messages: Belongs to the LacAB/RpiB family.

157688:FVE77 RS11295
gene id: 157688:FVE77_RS11295
uniprot id: A0A510JJY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

157688:FVE77 RS07485
gene id: 157688:FVE77_RS07485
uniprot id: A0A510JHQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

157688:FVE77 RS01485
gene id: 157688:FVE77_RS01485
uniprot id: A0A510JE94
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS06095
gene id: 157688:FVE77_RS06095
uniprot id: A0A510JH14
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

157688:FVE77 RS12070
gene id: 157688:FVE77_RS12070
uniprot id: A0A510JMV7
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS10635
gene id: 157688:FVE77_RS10635
uniprot id: A0A510JJH3
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS03280
gene id: 157688:FVE77_RS03280
uniprot id: A0A510JFQ6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

157688:FVE77 RS11070
gene id: 157688:FVE77_RS11070
uniprot id: A0A510JJR3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

157688:FVE77 RS09080
gene id: 157688:FVE77_RS09080
uniprot id: A0A510JLH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

157688:FVE77 RS05470
gene id: 157688:FVE77_RS05470
uniprot id: A0A510JGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

157688:FVE77 RS09005
gene id: 157688:FVE77_RS09005
uniprot id: A0A510JIL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS05795
gene id: 157688:FVE77_RS05795
uniprot id: A0A510JKZ0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

157688:FVE77 RS06435
gene id: 157688:FVE77_RS06435
uniprot id: A0A510JH52
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

157688:FVE77 RS07335
gene id: 157688:FVE77_RS07335
uniprot id: A0A510JHY0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

157688:FVE77 RS02945
gene id: 157688:FVE77_RS02945
uniprot id: A0A510JF05
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS05335
gene id: 157688:FVE77_RS05335
uniprot id: A0A510JGK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS04595
gene id: 157688:FVE77_RS04595
uniprot id: A0A510JK94
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

157688:FVE77 RS08930
gene id: 157688:FVE77_RS08930
uniprot id: A0A510JLE1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

157688:FVE77 RS00250
gene id: 157688:FVE77_RS00250
uniprot id: A0A510JGL0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

157688:FVE77 RS00890
gene id: 157688:FVE77_RS00890
uniprot id: A0A510JE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

157688:FVE77 RS06750
gene id: 157688:FVE77_RS06750
uniprot id: A0A510JH94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

157688:FVE77 RS03120
gene id: 157688:FVE77_RS03120
uniprot id: A0A510JI61
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

157688:FVE77 RS11385
gene id: 157688:FVE77_RS11385
uniprot id: A0A510JK90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

157688:FVE77 RS00430
gene id: 157688:FVE77_RS00430
uniprot id: A0A510JDN4
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

157688:FVE77 RS02035
gene id: 157688:FVE77_RS02035
uniprot id: A0A510JEJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

157688:FVE77 RS00110
gene id: 157688:FVE77_RS00110
uniprot id: A0A510JDQ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS10470
gene id: 157688:FVE77_RS10470
uniprot id: A0A510JJF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

157688:FVE77 RS09190
gene id: 157688:FVE77_RS09190
uniprot id: A0A510JIP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

157688:FVE77 RS11935
gene id: 157688:FVE77_RS11935
uniprot id: A0A510JKA3
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

157688:FVE77 RS02530
gene id: 157688:FVE77_RS02530
uniprot id: A0A510JFD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

157688:FVE77 RS00270
gene id: 157688:FVE77_RS00270
uniprot id: A0A510JDJ8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

157688:FVE77 RS10040
gene id: 157688:FVE77_RS10040
uniprot id: A0A510JJ66
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

157688:FVE77 RS12980
gene id: 157688:FVE77_RS12980
uniprot id: A0A510JKM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

157688:FVE77 RS09245
gene id: 157688:FVE77_RS09245
uniprot id: A0A510JIP4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

157688:FVE77 RS04195
gene id: 157688:FVE77_RS04195
uniprot id: A0A510JK04
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

157688:FVE77 RS11050
gene id: 157688:FVE77_RS11050
uniprot id: A0A510JK34
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

157688:FVE77 RS00395
gene id: 157688:FVE77_RS00395
uniprot id: A0A510JGN8
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

157688:FVE77 RS08310
gene id: 157688:FVE77_RS08310
uniprot id: A0A510JIJ2
names: Similarity
messages: Belongs to the UPF0045 family.

157688:FVE77 RS05090
gene id: 157688:FVE77_RS05090
uniprot id: A0A510JJ07
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

157688:FVE77 RS02010
gene id: 157688:FVE77_RS02010
uniprot id: A0A510JES6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS06055
gene id: 157688:FVE77_RS06055
uniprot id: A0A510JGX2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

157688:FVE77 RS00985
gene id: 157688:FVE77_RS00985
uniprot id: A0A510JGK8
names: Similarity
messages: Belongs to the IMPACT family.

157688:FVE77 RS00285
gene id: 157688:FVE77_RS00285
uniprot id: A0A510JDK9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

157688:FVE77 RS07075
gene id: 157688:FVE77_RS07075
uniprot id: A0A510JKG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

157688:FVE77 RS03950
gene id: 157688:FVE77_RS03950
uniprot id: A0A510JIN1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

157688:FVE77 RS11355
gene id: 157688:FVE77_RS11355
uniprot id: A0A510JJW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

157688:FVE77 RS06725
gene id: 157688:FVE77_RS06725
uniprot id: A0A510JHB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

157688:FVE77 RS08900
gene id: 157688:FVE77_RS08900
uniprot id: A0A510JIH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

157688:FVE77 RS04695
gene id: 157688:FVE77_RS04695
uniprot id: A0A510JG07
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

157688:FVE77 RS09740
gene id: 157688:FVE77_RS09740
uniprot id: A0A510JJ04
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

157688:FVE77 RS00475
gene id: 157688:FVE77_RS00475
uniprot id: A0A510JG96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS02675
gene id: 157688:FVE77_RS02675
uniprot id: A0A510JF01
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

157688:FVE77 RS00520
gene id: 157688:FVE77_RS00520
uniprot id: A0A510JGA7
names: Similarity
messages: Belongs to the TlyA family.

157688:FVE77 RS02495
gene id: 157688:FVE77_RS02495
uniprot id: A0A510JER9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

157688:FVE77 RS07695
gene id: 157688:FVE77_RS07695
uniprot id: A0A510JHT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

157688:FVE77 RS05920
gene id: 157688:FVE77_RS05920
uniprot id: A0A510JGR6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

157688:FVE77 RS02940
gene id: 157688:FVE77_RS02940
uniprot id: A0A510JF57
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

157688:FVE77 RS12030
gene id: 157688:FVE77_RS12030
uniprot id: A0A510JKB6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

157688:FVE77 RS01425
gene id: 157688:FVE77_RS01425
uniprot id: A0A510JET1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

157688:FVE77 RS04090
gene id: 157688:FVE77_RS04090
uniprot id: A0A510JFN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

157688:FVE77 RS09010
gene id: 157688:FVE77_RS09010
uniprot id: A0A510JL80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS10060
gene id: 157688:FVE77_RS10060
uniprot id: A0A510JJJ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

157688:FVE77 RS09615
gene id: 157688:FVE77_RS09615
uniprot id: A0A510JNE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

157688:FVE77 RS04150
gene id: 157688:FVE77_RS04150
uniprot id: A0A510JFX4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

157688:FVE77 RS02330
gene id: 157688:FVE77_RS02330
uniprot id: A0A510JEU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

157688:FVE77 RS04895
gene id: 157688:FVE77_RS04895
uniprot id: A0A510JG47
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

157688:FVE77 RS02950
gene id: 157688:FVE77_RS02950
uniprot id: A0A510JF53
names: Similarity
messages: Belongs to the band 7/mec-2 family.

157688:FVE77 RS07780
gene id: 157688:FVE77_RS07780
uniprot id: A0A510JHV9
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

157688:FVE77 RS11485
gene id: 157688:FVE77_RS11485
uniprot id: A0A510JKA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS00730
gene id: 157688:FVE77_RS00730
uniprot id: A0A510JHZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS04085
gene id: 157688:FVE77_RS04085
uniprot id: A0A510JIC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

157688:FVE77 RS05425
gene id: 157688:FVE77_RS05425
uniprot id: A0A510JGJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

157688:FVE77 RS00300
gene id: 157688:FVE77_RS00300
uniprot id: A0A510JGL6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

157688:FVE77 RS08265
gene id: 157688:FVE77_RS08265
uniprot id: A0A510JI94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

157688:FVE77 RS11495
gene id: 157688:FVE77_RS11495
uniprot id: A0A510JJY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

157688:FVE77 RS09800
gene id: 157688:FVE77_RS09800
uniprot id: A0A510JLP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

157688:FVE77 RS04580
gene id: 157688:FVE77_RS04580
uniprot id: A0A510JG48
names: Similarity
messages: Belongs to the ArsC family.

157688:FVE77 RS07500
gene id: 157688:FVE77_RS07500
uniprot id: A0A510JM43
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

157688:FVE77 RS04900
gene id: 157688:FVE77_RS04900
uniprot id: A0A510JKE9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

157688:FVE77 RS05050
gene id: 157688:FVE77_RS05050
uniprot id: A0A510JKI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

157688:FVE77 RS00690
gene id: 157688:FVE77_RS00690
uniprot id: A0A510JGU7
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

157688:FVE77 RS08810
gene id: 157688:FVE77_RS08810
uniprot id: A0A510JIF0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

157688:FVE77 RS11150
gene id: 157688:FVE77_RS11150
uniprot id: A0A510JPE5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS02695
gene id: 157688:FVE77_RS02695
uniprot id: A0A510JHI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

157688:FVE77 RS10940
gene id: 157688:FVE77_RS10940
uniprot id: A0A510JMH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

157688:FVE77 RS10215
gene id: 157688:FVE77_RS10215
uniprot id: A0A510JJA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

157688:FVE77 RS10820
gene id: 157688:FVE77_RS10820
uniprot id: A0A510JJZ1
names: Similarity
messages: Belongs to the leucine-binding protein family.

157688:FVE77 RS09510
gene id: 157688:FVE77_RS09510
uniprot id: A0A510JIU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

157688:FVE77 RS02315
gene id: 157688:FVE77_RS02315
uniprot id: A0A510JEY5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

157688:FVE77 RS05320
gene id: 157688:FVE77_RS05320
uniprot id: A0A510JGI3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

157688:FVE77 RS11035
gene id: 157688:FVE77_RS11035
uniprot id: A0A510JPC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

157688:FVE77 RS10190
gene id: 157688:FVE77_RS10190
uniprot id: A0A510JNT1
names: Similarity
messages: Belongs to the peptidase M16 family.

157688:FVE77 RS09455
gene id: 157688:FVE77_RS09455
uniprot id: A0A510JIT5
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS01535
gene id: 157688:FVE77_RS01535
uniprot id: A0A510JEI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

157688:FVE77 RS04545
gene id: 157688:FVE77_RS04545
uniprot id: A0A510JK76
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS04315
gene id: 157688:FVE77_RS04315
uniprot id: A0A510JG15
names: Similarity
messages: Belongs to the heat shock protein 70 family.

157688:FVE77 RS07595
gene id: 157688:FVE77_RS07595
uniprot id: A0A510JHS6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

157688:FVE77 RS10895
gene id: 157688:FVE77_RS10895
uniprot id: A0A510JP88
names: Similarity
messages: Belongs to the YciI family.

157688:FVE77 RS06585
gene id: 157688:FVE77_RS06585
uniprot id: A0A510JHC2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.

157688:FVE77 RS02030
gene id: 157688:FVE77_RS02030
uniprot id: A0A510JH62
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

157688:FVE77 RS05440
gene id: 157688:FVE77_RS05440
uniprot id: A0A510JJ75
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

157688:FVE77 RS07110
gene id: 157688:FVE77_RS07110
uniprot id: A0A510JHG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

157688:FVE77 RS09720
gene id: 157688:FVE77_RS09720
uniprot id: A0A510JLU7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

157688:FVE77 RS03240
gene id: 157688:FVE77_RS03240
uniprot id: A0A510JFE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

157688:FVE77 RS11815
gene id: 157688:FVE77_RS11815
uniprot id: A0A510JK56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS07585
gene id: 157688:FVE77_RS07585
uniprot id: A0A510JHS0
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS09785
gene id: 157688:FVE77_RS09785
uniprot id: A0A510JJ13
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

157688:FVE77 RS10725
gene id: 157688:FVE77_RS10725
uniprot id: A0A510JJN9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

157688:FVE77 RS11360
gene id: 157688:FVE77_RS11360
uniprot id: A0A510JMG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

157688:FVE77 RS09525
gene id: 157688:FVE77_RS09525
uniprot id: A0A510JLR1
names: Similarity
messages: Belongs to the FGGY kinase family.

157688:FVE77 RS12060
gene id: 157688:FVE77_RS12060
uniprot id: A0A510JK96
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

157688:FVE77 RS07025
gene id: 157688:FVE77_RS07025
uniprot id: A0A510JHH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

157688:FVE77 RS00450
gene id: 157688:FVE77_RS00450
uniprot id: A0A510JE93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

157688:FVE77 RS09765
gene id: 157688:FVE77_RS09765
uniprot id: A0A510JJ38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

157688:FVE77 RS06500
gene id: 157688:FVE77_RS06500
uniprot id: A0A510JH61
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

157688:FVE77 RS02785
gene id: 157688:FVE77_RS02785
uniprot id: A0A510JHL0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

157688:FVE77 RS08065
gene id: 157688:FVE77_RS08065
uniprot id: A0A510JID4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

157688:FVE77 RS09205
gene id: 157688:FVE77_RS09205
uniprot id: A0A510JLB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

157688:FVE77 RS07285
gene id: 157688:FVE77_RS07285
uniprot id: A0A510JHX2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

157688:FVE77 RS11015
gene id: 157688:FVE77_RS11015
uniprot id: A0A510JJP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

157688:FVE77 RS05175
gene id: 157688:FVE77_RS05175
uniprot id: A0A510JGS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

157688:FVE77 RS02190
gene id: 157688:FVE77_RS02190
uniprot id: A0A510JIV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

157688:FVE77 RS01855
gene id: 157688:FVE77_RS01855
uniprot id: A0A510JEM1
names: Similarity
messages: Belongs to the peptidase S14 family.

157688:FVE77 RS09265
gene id: 157688:FVE77_RS09265
uniprot id: A0A510JN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

157688:FVE77 RS06415
gene id: 157688:FVE77_RS06415
uniprot id: A0A510JH60
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

157688:FVE77 RS12015
gene id: 157688:FVE77_RS12015
uniprot id: A0A510JMU7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

157688:FVE77 RS04230
gene id: 157688:FVE77_RS04230
uniprot id: A0A510JFY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

157688:FVE77 RS02150
gene id: 157688:FVE77_RS02150
uniprot id: A0A510JHQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

157688:FVE77 RS06925
gene id: 157688:FVE77_RS06925
uniprot id: A0A510JHF4
names: Similarity
messages: Belongs to the threonine synthase family.

157688:FVE77 RS06695
gene id: 157688:FVE77_RS06695
uniprot id: A0A510JHE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

157688:FVE77 RS12010
gene id: 157688:FVE77_RS12010
uniprot id: A0A510JK92
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

157688:FVE77 RS03040
gene id: 157688:FVE77_RS03040
uniprot id: A0A510JF26
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

157688:FVE77 RS07930
gene id: 157688:FVE77_RS07930
uniprot id: A0A510JHY3
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS11505
gene id: 157688:FVE77_RS11505
uniprot id: A0A510JJY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

157688:FVE77 RS04120
gene id: 157688:FVE77_RS04120
uniprot id: A0A510JFU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

157688:FVE77 RS02715
gene id: 157688:FVE77_RS02715
uniprot id: A0A510JFH0
names: Similarity
messages: Belongs to the Gram-positive plasmids replication protein type 1 family.

157688:FVE77 RS11750
gene id: 157688:FVE77_RS11750
uniprot id: A0A510JKG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

157688:FVE77 RS11145
gene id: 157688:FVE77_RS11145
uniprot id: A0A510JJS7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

157688:FVE77 RS06425
gene id: 157688:FVE77_RS06425
uniprot id: A0A510JHF5
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

157688:FVE77 RS00005
gene id: 157688:FVE77_RS00005
uniprot id: A0A510JE16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

157688:FVE77 RS11340
gene id: 157688:FVE77_RS11340
uniprot id: A0A510JJZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

157688:FVE77 RS05705
gene id: 157688:FVE77_RS05705
uniprot id: A0A510JJM4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

157688:FVE77 RS07705
gene id: 157688:FVE77_RS07705
uniprot id: A0A510JKR9
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

157688:FVE77 RS12105
gene id: 157688:FVE77_RS12105
uniprot id: A0A510JKA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

157688:FVE77 RS05235
gene id: 157688:FVE77_RS05235
uniprot id: A0A510JGJ1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

157688:FVE77 RS11475
gene id: 157688:FVE77_RS11475
uniprot id: A0A510JK00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

157688:FVE77 RS07915
gene id: 157688:FVE77_RS07915
uniprot id: A0A510JI24
names: Similarity
messages: Belongs to the YoeB family.

157688:FVE77 RS11030
gene id: 157688:FVE77_RS11030
uniprot id: A0A510JMA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

157688:FVE77 RS09540
gene id: 157688:FVE77_RS09540
uniprot id: A0A510JIV6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

157688:FVE77 RS08965
gene id: 157688:FVE77_RS08965
uniprot id: A0A510JIH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

157688:FVE77 RS06805
gene id: 157688:FVE77_RS06805
uniprot id: A0A510JHB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS02220
gene id: 157688:FVE77_RS02220
uniprot id: A0A510JET0
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS05380
gene id: 157688:FVE77_RS05380
uniprot id: A0A510JGV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

157688:FVE77 RS09100
gene id: 157688:FVE77_RS09100
uniprot id: A0A510JIL1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

157688:FVE77 RS10580
gene id: 157688:FVE77_RS10580
uniprot id: A0A510JP32
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

157688:FVE77 RS03100
gene id: 157688:FVE77_RS03100
uniprot id: A0A510JHR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS01510
gene id: 157688:FVE77_RS01510
uniprot id: A0A510JIH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

157688:FVE77 RS07655
gene id: 157688:FVE77_RS07655
uniprot id: A0A510JHU8
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

157688:FVE77 RS01160
gene id: 157688:FVE77_RS01160
uniprot id: A0A510JE14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

157688:FVE77 RS03260
gene id: 157688:FVE77_RS03260
uniprot id: A0A510JF84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

157688:FVE77 RS01125
gene id: 157688:FVE77_RS01125
uniprot id: A0A510JH32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS02135
gene id: 157688:FVE77_RS02135
uniprot id: A0A510JEL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

157688:FVE77 RS05220
gene id: 157688:FVE77_RS05220
uniprot id: A0A510JJC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS06325
gene id: 157688:FVE77_RS06325
uniprot id: A0A510JHE3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

157688:FVE77 RS07865
gene id: 157688:FVE77_RS07865
uniprot id: A0A510JI14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

157688:FVE77 RS10310
gene id: 157688:FVE77_RS10310
uniprot id: A0A510JJC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

157688:FVE77 RS04630
gene id: 157688:FVE77_RS04630
uniprot id: A0A510JFZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

157688:FVE77 RS03070
gene id: 157688:FVE77_RS03070
uniprot id: A0A510JI56
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

157688:FVE77 RS04625
gene id: 157688:FVE77_RS04625
uniprot id: A0A510JG49
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

157688:FVE77 RS02335
gene id: 157688:FVE77_RS02335
uniprot id: A0A510JHC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

157688:FVE77 RS05930
gene id: 157688:FVE77_RS05930
uniprot id: A0A510JGQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

157688:FVE77 RS05875
gene id: 157688:FVE77_RS05875
uniprot id: A0A510JGU3
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

157688:FVE77 RS06365
gene id: 157688:FVE77_RS06365
uniprot id: A0A510JH47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

157688:FVE77 RS10210
gene id: 157688:FVE77_RS10210
uniprot id: A0A510JJE3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

157688:FVE77 RS07260
gene id: 157688:FVE77_RS07260
uniprot id: A0A510JKA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

157688:FVE77 RS08030
gene id: 157688:FVE77_RS08030
uniprot id: A0A510JHZ4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

157688:FVE77 RS04205
gene id: 157688:FVE77_RS04205
uniprot id: A0A510JIT4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS06335
gene id: 157688:FVE77_RS06335
uniprot id: A0A510JH37
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

157688:FVE77 RS11375
gene id: 157688:FVE77_RS11375
uniprot id: A0A510JJX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

157688:FVE77 RS10655
gene id: 157688:FVE77_RS10655
uniprot id: A0A510JJI4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

157688:FVE77 RS03495
gene id: 157688:FVE77_RS03495
uniprot id: A0A510JFI0
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

157688:FVE77 RS06090
gene id: 157688:FVE77_RS06090
uniprot id: A0A510JHA1
names: Similarity
messages: Belongs to the YoeB family.

157688:FVE77 RS06315
gene id: 157688:FVE77_RS06315
uniprot id: A0A510JH38
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

157688:FVE77 RS07680
gene id: 157688:FVE77_RS07680
uniprot id: A0A510JHS4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

157688:FVE77 RS04200
gene id: 157688:FVE77_RS04200
uniprot id: A0A510JFY7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

157688:FVE77 RS06895
gene id: 157688:FVE77_RS06895
uniprot id: A0A510JHF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

157688:FVE77 RS00185
gene id: 157688:FVE77_RS00185
uniprot id: A0A510JDJ1
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS00400
gene id: 157688:FVE77_RS00400
uniprot id: A0A510JE82
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

157688:FVE77 RS08110
gene id: 157688:FVE77_RS08110
uniprot id: A0A510JIE4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS07445
gene id: 157688:FVE77_RS07445
uniprot id: A0A510JKD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

157688:FVE77 RS10105
gene id: 157688:FVE77_RS10105
uniprot id: A0A510JM23
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

157688:FVE77 RS10705
gene id: 157688:FVE77_RS10705
uniprot id: A0A510JJJ5
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS04550
gene id: 157688:FVE77_RS04550
uniprot id: A0A510JG51
names: Similarity
messages: Belongs to the YjdM family.

157688:FVE77 RS06950
gene id: 157688:FVE77_RS06950
uniprot id: A0A510JHD6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS09250
gene id: 157688:FVE77_RS09250
uniprot id: A0A510JIS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

157688:FVE77 RS07510
gene id: 157688:FVE77_RS07510
uniprot id: A0A510JKN7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

157688:FVE77 RS11910
gene id: 157688:FVE77_RS11910
uniprot id: A0A510JK69
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

157688:FVE77 RS07785
gene id: 157688:FVE77_RS07785
uniprot id: A0A510JKJ2
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS11825
gene id: 157688:FVE77_RS11825
uniprot id: A0A510JK60
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

157688:FVE77 RS09790
gene id: 157688:FVE77_RS09790
uniprot id: A0A510JJ11
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

157688:FVE77 RS08845
gene id: 157688:FVE77_RS08845
uniprot id: A0A510JIG4
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

157688:FVE77 RS10980
gene id: 157688:FVE77_RS10980
uniprot id: A0A510JM96
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

157688:FVE77 RS01590
gene id: 157688:FVE77_RS01590
uniprot id: A0A510JE90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

157688:FVE77 RS00780
gene id: 157688:FVE77_RS00780
uniprot id: A0A510JI04
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

157688:FVE77 RS02285
gene id: 157688:FVE77_RS02285
uniprot id: A0A510JEP4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

157688:FVE77 RS07140
gene id: 157688:FVE77_RS07140
uniprot id: A0A510JHK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS05680
gene id: 157688:FVE77_RS05680
uniprot id: A0A510JGR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

157688:FVE77 RS00135
gene id: 157688:FVE77_RS00135
uniprot id: A0A510JDI3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

157688:FVE77 RS10560
gene id: 157688:FVE77_RS10560
uniprot id: A0A510JJI0
names: Similarity
messages: Belongs to the peptidase S8 family.

157688:FVE77 RS06675
gene id: 157688:FVE77_RS06675
uniprot id: A0A510JLJ2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

157688:FVE77 RS03955
gene id: 157688:FVE77_RS03955
uniprot id: A0A510JG36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

157688:FVE77 RS07665
gene id: 157688:FVE77_RS07665
uniprot id: A0A510JI54
names: Similarity
messages: Belongs to the BMP lipoprotein family.

157688:FVE77 RS09805
gene id: 157688:FVE77_RS09805
uniprot id: A0A510JJ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

157688:FVE77 RS01220
gene id: 157688:FVE77_RS01220
uniprot id: A0A510JE97
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

157688:FVE77 RS01475
gene id: 157688:FVE77_RS01475
uniprot id: A0A510JEU0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

157688:FVE77 RS08365
gene id: 157688:FVE77_RS08365
uniprot id: A0A510JIB7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

157688:FVE77 RS07770
gene id: 157688:FVE77_RS07770
uniprot id: A0A510JHX9
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

157688:FVE77 RS07175
gene id: 157688:FVE77_RS07175
uniprot id: A0A510JKH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

157688:FVE77 RS03125
gene id: 157688:FVE77_RS03125
uniprot id: A0A510JFL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS10490
gene id: 157688:FVE77_RS10490
uniprot id: A0A510JJH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS11745
gene id: 157688:FVE77_RS11745
uniprot id: A0A510JMW6
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS11895
gene id: 157688:FVE77_RS11895
uniprot id: A0A510JKJ5
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

157688:FVE77 RS00735
gene id: 157688:FVE77_RS00735
uniprot id: A0A510JE12
names: Similarity
messages: Belongs to the peptidase M18 family.

157688:FVE77 RS09150
gene id: 157688:FVE77_RS09150
uniprot id: A0A510JIN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

157688:FVE77 RS04450
gene id: 157688:FVE77_RS04450
uniprot id: A0A510JIX9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

157688:FVE77 RS08705
gene id: 157688:FVE77_RS08705
uniprot id: A0A510JID1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

157688:FVE77 RS04500
gene id: 157688:FVE77_RS04500
uniprot id: A0A510JG41
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

157688:FVE77 RS08730
gene id: 157688:FVE77_RS08730
uniprot id: A0A510JIR0
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

157688:FVE77 RS05575
gene id: 157688:FVE77_RS05575
uniprot id: A0A510JGI8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

157688:FVE77 RS11350
gene id: 157688:FVE77_RS11350
uniprot id: A0A510JJX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

157688:FVE77 RS11205
gene id: 157688:FVE77_RS11205
uniprot id: A0A510JJT2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

157688:FVE77 RS11275
gene id: 157688:FVE77_RS11275
uniprot id: A0A510JPH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

157688:FVE77 RS12095
gene id: 157688:FVE77_RS12095
uniprot id: A0A510JKP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS06085
gene id: 157688:FVE77_RS06085
uniprot id: A0A510JJV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS02970
gene id: 157688:FVE77_RS02970
uniprot id: A0A510JJ88
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS02420
gene id: 157688:FVE77_RS02420
uniprot id: A0A510JF03
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

157688:FVE77 RS00720
gene id: 157688:FVE77_RS00720
uniprot id: A0A510JGF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

157688:FVE77 RS10225
gene id: 157688:FVE77_RS10225
uniprot id: A0A510JJA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

157688:FVE77 RS04635
gene id: 157688:FVE77_RS04635
uniprot id: A0A510JG56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

157688:FVE77 RS02340
gene id: 157688:FVE77_RS02340
uniprot id: A0A510JEQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

157688:FVE77 RS05945
gene id: 157688:FVE77_RS05945
uniprot id: A0A510JJS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

157688:FVE77 RS01120
gene id: 157688:FVE77_RS01120
uniprot id: A0A510JE76
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS09725
gene id: 157688:FVE77_RS09725
uniprot id: A0A510JJB2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

157688:FVE77 RS06685
gene id: 157688:FVE77_RS06685
uniprot id: A0A510JK73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

157688:FVE77 RS04100
gene id: 157688:FVE77_RS04100
uniprot id: A0A510JFW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

157688:FVE77 RS05645
gene id: 157688:FVE77_RS05645
uniprot id: A0A510JKV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

157688:FVE77 RS04505
gene id: 157688:FVE77_RS04505
uniprot id: A0A510JIZ3
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS04175
gene id: 157688:FVE77_RS04175
uniprot id: A0A510JFR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

157688:FVE77 RS04030
gene id: 157688:FVE77_RS04030
uniprot id: A0A510JIB9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

157688:FVE77 RS11625
gene id: 157688:FVE77_RS11625
uniprot id: A0A510JML6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

157688:FVE77 RS00380
gene id: 157688:FVE77_RS00380
uniprot id: A0A510JDM8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

157688:FVE77 RS06820
gene id: 157688:FVE77_RS06820
uniprot id: A0A510JLM9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

157688:FVE77 RS04045
gene id: 157688:FVE77_RS04045
uniprot id: A0A510JFV5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

157688:FVE77 RS06890
gene id: 157688:FVE77_RS06890
uniprot id: A0A510JHH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

157688:FVE77 RS10170
gene id: 157688:FVE77_RS10170
uniprot id: A0A510JJ91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

157688:FVE77 RS05955
gene id: 157688:FVE77_RS05955
uniprot id: A0A510JGY7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

157688:FVE77 RS04600
gene id: 157688:FVE77_RS04600
uniprot id: A0A510JG59
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

157688:FVE77 RS01225
gene id: 157688:FVE77_RS01225
uniprot id: A0A510JH58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

157688:FVE77 RS10055
gene id: 157688:FVE77_RS10055
uniprot id: A0A510JM13
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS07115
gene id: 157688:FVE77_RS07115
uniprot id: A0A510JLV2
names: Similarity
messages: Belongs to the DEAD box helicase family.

157688:FVE77 RS02610
gene id: 157688:FVE77_RS02610
uniprot id: A0A510JF18
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

157688:FVE77 RS01450
gene id: 157688:FVE77_RS01450
uniprot id: A0A510JGV1
names: Similarity
messages: Belongs to the peptidase C40 family.

157688:FVE77 RS10175
gene id: 157688:FVE77_RS10175
uniprot id: A0A510JJ93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

157688:FVE77 RS04905
gene id: 157688:FVE77_RS04905
uniprot id: A0A510JGA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

157688:FVE77 RS11020
gene id: 157688:FVE77_RS11020
uniprot id: A0A510JJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

157688:FVE77 RS02040
gene id: 157688:FVE77_RS02040
uniprot id: A0A510JIS8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

157688:FVE77 RS11345
gene id: 157688:FVE77_RS11345
uniprot id: A0A510JJV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

157688:FVE77 RS10360
gene id: 157688:FVE77_RS10360
uniprot id: A0A510JJC9
names: Similarity
messages: Belongs to the CapA family.

157688:FVE77 RS11550
gene id: 157688:FVE77_RS11550
uniprot id: A0A510JK09
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

157688:FVE77 RS05450
gene id: 157688:FVE77_RS05450
uniprot id: A0A510JKR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

157688:FVE77 RS08375
gene id: 157688:FVE77_RS08375
uniprot id: A0A510JI65
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

157688:FVE77 RS06000
gene id: 157688:FVE77_RS06000
uniprot id: A0A510JH80
names: Similarity
messages: Belongs to the nitroreductase family.

157688:FVE77 RS08095
gene id: 157688:FVE77_RS08095
uniprot id: A0A510JME8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS06790
gene id: 157688:FVE77_RS06790
uniprot id: A0A510JHG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS09895
gene id: 157688:FVE77_RS09895
uniprot id: A0A510JJ37
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

157688:FVE77 RS09140
gene id: 157688:FVE77_RS09140
uniprot id: A0A510JIY5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

157688:FVE77 RS10150
gene id: 157688:FVE77_RS10150
uniprot id: A0A510JM31
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

157688:FVE77 RS01395
gene id: 157688:FVE77_RS01395
uniprot id: A0A510JE86
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

157688:FVE77 RS02670
gene id: 157688:FVE77_RS02670
uniprot id: A0A510JF48
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS10165
gene id: 157688:FVE77_RS10165
uniprot id: A0A510JJ97
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

157688:FVE77 RS11685
gene id: 157688:FVE77_RS11685
uniprot id: A0A510JK29
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

157688:FVE77 RS03140
gene id: 157688:FVE77_RS03140
uniprot id: A0A510JF46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

157688:FVE77 RS11235
gene id: 157688:FVE77_RS11235
uniprot id: A0A510JMM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

157688:FVE77 RS04095
gene id: 157688:FVE77_RS04095
uniprot id: A0A510JJY3
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

157688:FVE77 RS05325
gene id: 157688:FVE77_RS05325
uniprot id: A0A510JJE2
names: Similarity
messages: Belongs to the NAPRTase family.

157688:FVE77 RS11270
gene id: 157688:FVE77_RS11270
uniprot id: A0A510JJV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

157688:FVE77 RS06615
gene id: 157688:FVE77_RS06615
uniprot id: A0A510JH56
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS05900
gene id: 157688:FVE77_RS05900
uniprot id: A0A510JJR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS07065
gene id: 157688:FVE77_RS07065
uniprot id: A0A510JLU2
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

157688:FVE77 RS02410
gene id: 157688:FVE77_RS02410
uniprot id: A0A510JHT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

157688:FVE77 RS04260
gene id: 157688:FVE77_RS04260
uniprot id: A0A510JG91
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

157688:FVE77 RS05695
gene id: 157688:FVE77_RS05695
uniprot id: A0A510JKW8
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS00335
gene id: 157688:FVE77_RS00335
uniprot id: A0A510JDL9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

157688:FVE77 RS02840
gene id: 157688:FVE77_RS02840
uniprot id: A0A510JFI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

157688:FVE77 RS09570
gene id: 157688:FVE77_RS09570
uniprot id: A0A510JIZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

157688:FVE77 RS10985
gene id: 157688:FVE77_RS10985
uniprot id: A0A510JJP6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS04395
gene id: 157688:FVE77_RS04395
uniprot id: A0A510JG23
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

157688:FVE77 RS01165
gene id: 157688:FVE77_RS01165
uniprot id: A0A510JI88
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

157688:FVE77 RS08940
gene id: 157688:FVE77_RS08940
uniprot id: A0A510JIN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

157688:FVE77 RS01250
gene id: 157688:FVE77_RS01250
uniprot id: A0A510JGQ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

157688:FVE77 RS11455
gene id: 157688:FVE77_RS11455
uniprot id: A0A510JJY4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS02130
gene id: 157688:FVE77_RS02130
uniprot id: A0A510JH83
names: Similarity
messages: Belongs to the peptidase S51 family.

157688:FVE77 RS08850
gene id: 157688:FVE77_RS08850
uniprot id: A0A510JII9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

157688:FVE77 RS03285
gene id: 157688:FVE77_RS03285
uniprot id: A0A510JFF5
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

157688:FVE77 RS05715
gene id: 157688:FVE77_RS05715
uniprot id: A0A510JGT3
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

157688:FVE77 RS06220
gene id: 157688:FVE77_RS06220
uniprot id: A0A510JH20
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

157688:FVE77 RS09755
gene id: 157688:FVE77_RS09755
uniprot id: A0A510JJ02
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

157688:FVE77 RS03165
gene id: 157688:FVE77_RS03165
uniprot id: A0A510JFC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

157688:FVE77 RS11325
gene id: 157688:FVE77_RS11325
uniprot id: A0A510JPI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

157688:FVE77 RS02195
gene id: 157688:FVE77_RS02195
uniprot id: A0A510JEU9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS01325
gene id: 157688:FVE77_RS01325
uniprot id: A0A510JEQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS09710
gene id: 157688:FVE77_RS09710
uniprot id: A0A510JNG2
names: Similarity
messages: Belongs to the Dps family.

157688:FVE77 RS04235
gene id: 157688:FVE77_RS04235
uniprot id: A0A510JIF8
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

157688:FVE77 RS02345
gene id: 157688:FVE77_RS02345
uniprot id: A0A510JIX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

157688:FVE77 RS06660
gene id: 157688:FVE77_RS06660
uniprot id: A0A510JJX2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS10075
gene id: 157688:FVE77_RS10075
uniprot id: A0A510JJ73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

157688:FVE77 RS11845
gene id: 157688:FVE77_RS11845
uniprot id: A0A510JKI7
names: Subcellular Location Annotation
messages: Bacterial microcompartment

157688:FVE77 RS06540
gene id: 157688:FVE77_RS06540
uniprot id: A0A510JH79
names: Similarity
messages: Belongs to the ribF family.

157688:FVE77 RS05205
gene id: 157688:FVE77_RS05205
uniprot id: A0A510JGB2
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

157688:FVE77 RS01185
gene id: 157688:FVE77_RS01185
uniprot id: A0A510JEB6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

157688:FVE77 RS06755
gene id: 157688:FVE77_RS06755
uniprot id: A0A510JHB1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

157688:FVE77 RS09085
gene id: 157688:FVE77_RS09085
uniprot id: A0A510JIX3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

157688:FVE77 RS09310
gene id: 157688:FVE77_RS09310
uniprot id: A0A510JIP5
names: Similarity
messages: Belongs to the peptidase A24 family.

157688:FVE77 RS08040
gene id: 157688:FVE77_RS08040
uniprot id: A0A510JKP1
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS12115
gene id: 157688:FVE77_RS12115
uniprot id: A0A510JKB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

157688:FVE77 RS11735
gene id: 157688:FVE77_RS11735
uniprot id: A0A510JPR3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

157688:FVE77 RS10995
gene id: 157688:FVE77_RS10995
uniprot id: A0A510JJQ4
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

157688:FVE77 RS06760
gene id: 157688:FVE77_RS06760
uniprot id: A0A510JJZ3
names: Similarity
messages: Belongs to the peptidase M13 family.

157688:FVE77 RS02890
gene id: 157688:FVE77_RS02890
uniprot id: A0A510JF45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

157688:FVE77 RS07760
gene id: 157688:FVE77_RS07760
uniprot id: A0A510JI74
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

157688:FVE77 RS09630
gene id: 157688:FVE77_RS09630
uniprot id: A0A510JJ85
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

157688:FVE77 RS11705
gene id: 157688:FVE77_RS11705
uniprot id: A0A510JKF1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

157688:FVE77 RS05190
gene id: 157688:FVE77_RS05190
uniprot id: A0A510JGA6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

157688:FVE77 RS02630
gene id: 157688:FVE77_RS02630
uniprot id: A0A510JEZ3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

157688:FVE77 RS06485
gene id: 157688:FVE77_RS06485
uniprot id: A0A510JH69
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

157688:FVE77 RS09640
gene id: 157688:FVE77_RS09640
uniprot id: A0A510JIY2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

157688:FVE77 RS01605
gene id: 157688:FVE77_RS01605
uniprot id: A0A510JEA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

157688:FVE77 RS11785
gene id: 157688:FVE77_RS11785
uniprot id: A0A510JK65
names: Similarity
messages: Belongs to the YoeB family.

157688:FVE77 RS02360
gene id: 157688:FVE77_RS02360
uniprot id: A0A510JFB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

157688:FVE77 RS09225
gene id: 157688:FVE77_RS09225
uniprot id: A0A510JLL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

157688:FVE77 RS10480
gene id: 157688:FVE77_RS10480
uniprot id: A0A510JJF8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

157688:FVE77 RS04165
gene id: 157688:FVE77_RS04165
uniprot id: A0A510JFY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

157688:FVE77 RS07475
gene id: 157688:FVE77_RS07475
uniprot id: A0A510JHS7
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

157688:FVE77 RS05170
gene id: 157688:FVE77_RS05170
uniprot id: A0A510JJB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

157688:FVE77 RS07540
gene id: 157688:FVE77_RS07540
uniprot id: A0A510JKF2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS11855
gene id: 157688:FVE77_RS11855
uniprot id: A0A510JK53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

157688:FVE77 RS03910
gene id: 157688:FVE77_RS03910
uniprot id: A0A510JG28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

157688:FVE77 RS04005
gene id: 157688:FVE77_RS04005
uniprot id: A0A510JG45
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS05195
gene id: 157688:FVE77_RS05195
uniprot id: A0A510JGF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

157688:FVE77 RS05095
gene id: 157688:FVE77_RS05095
uniprot id: A0A510JG86
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

157688:FVE77 RS04710
gene id: 157688:FVE77_RS04710
uniprot id: A0A510JJ29
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS09030
gene id: 157688:FVE77_RS09030
uniprot id: A0A510JLG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS00530
gene id: 157688:FVE77_RS00530
uniprot id: A0A510JHQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

157688:FVE77 RS07220
gene id: 157688:FVE77_RS07220
uniprot id: A0A510JHL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

157688:FVE77 RS03870
gene id: 157688:FVE77_RS03870
uniprot id: A0A510JG19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

157688:FVE77 RS10445
gene id: 157688:FVE77_RS10445
uniprot id: A0A510JM91
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

157688:FVE77 RS09215
gene id: 157688:FVE77_RS09215
uniprot id: A0A510JN62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

157688:FVE77 RS09445
gene id: 157688:FVE77_RS09445
uniprot id: A0A510JIV2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

157688:FVE77 RS06610
gene id: 157688:FVE77_RS06610
uniprot id: A0A510JJW5
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS11560
gene id: 157688:FVE77_RS11560
uniprot id: A0A510JMK9
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

157688:FVE77 RS02845
gene id: 157688:FVE77_RS02845
uniprot id: A0A510JEY7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

157688:FVE77 RS11930
gene id: 157688:FVE77_RS11930
uniprot id: A0A510JPV9
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

157688:FVE77 RS09705
gene id: 157688:FVE77_RS09705
uniprot id: A0A510JIY9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS05210
gene id: 157688:FVE77_RS05210
uniprot id: A0A510JKK5
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS08775
gene id: 157688:FVE77_RS08775
uniprot id: A0A510JLB8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

157688:FVE77 RS07650
gene id: 157688:FVE77_RS07650
uniprot id: A0A510JM67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

157688:FVE77 RS12085
gene id: 157688:FVE77_RS12085
uniprot id: A0A510JKD4
names: Subcellular Location Annotation
messages: Cytoplasm

157688:FVE77 RS11730
gene id: 157688:FVE77_RS11730
uniprot id: A0A510JK42
names: Similarity
messages: Belongs to the CobH/CbiC family.

157688:FVE77 RS08360
gene id: 157688:FVE77_RS08360
uniprot id: A0A510JIJ4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS06450
gene id: 157688:FVE77_RS06450
uniprot id: A0A510JJT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

157688:FVE77 RS10250
gene id: 157688:FVE77_RS10250
uniprot id: A0A510JM55
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

157688:FVE77 RS10900
gene id: 157688:FVE77_RS10900
uniprot id: A0A510JJN6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

157688:FVE77 RS06710
gene id: 157688:FVE77_RS06710
uniprot id: A0A510JH99
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

157688:FVE77 RS07790
gene id: 157688:FVE77_RS07790
uniprot id: A0A510JHV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

157688:FVE77 RS04185
gene id: 157688:FVE77_RS04185
uniprot id: A0A510JIE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS06060
gene id: 157688:FVE77_RS06060
uniprot id: A0A510JGU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

157688:FVE77 RS09025
gene id: 157688:FVE77_RS09025
uniprot id: A0A510JIM2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

157688:FVE77 RS02075
gene id: 157688:FVE77_RS02075
uniprot id: A0A510JEN2
names: Similarity
messages: Belongs to the UPF0145 family.

157688:FVE77 RS05365
gene id: 157688:FVE77_RS05365
uniprot id: A0A510JKN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

157688:FVE77 RS05340
gene id: 157688:FVE77_RS05340
uniprot id: A0A510JGH9
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS09935
gene id: 157688:FVE77_RS09935
uniprot id: A0A510JLR2
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

157688:FVE77 RS06045
gene id: 157688:FVE77_RS06045
uniprot id: A0A510JH91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

157688:FVE77 RS01150
gene id: 157688:FVE77_RS01150
uniprot id: A0A510JE30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

157688:FVE77 RS10975
gene id: 157688:FVE77_RS10975
uniprot id: A0A510JJP3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

157688:FVE77 RS00225
gene id: 157688:FVE77_RS00225
uniprot id: A0A510JDK5
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS07570
gene id: 157688:FVE77_RS07570
uniprot id: A0A510JHV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

157688:FVE77 RS07565
gene id: 157688:FVE77_RS07565
uniprot id: A0A510JI35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

157688:FVE77 RS04555
gene id: 157688:FVE77_RS04555
uniprot id: A0A510JJ06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

157688:FVE77 RS03150
gene id: 157688:FVE77_RS03150
uniprot id: A0A510JHS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

157688:FVE77 RS04920
gene id: 157688:FVE77_RS04920
uniprot id: A0A510JGD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

157688:FVE77 RS04265
gene id: 157688:FVE77_RS04265
uniprot id: A0A510JG06
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

157688:FVE77 RS09495
gene id: 157688:FVE77_RS09495
uniprot id: A0A510JIU3
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS01025
gene id: 157688:FVE77_RS01025
uniprot id: A0A510JE57
names: Similarity
messages: Belongs to the phosphohexose mutase family.

157688:FVE77 RS05675
gene id: 157688:FVE77_RS05675
uniprot id: A0A510JGK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

157688:FVE77 RS07580
gene id: 157688:FVE77_RS07580
uniprot id: A0A510JHP8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

157688:FVE77 RS07060
gene id: 157688:FVE77_RS07060
uniprot id: A0A510JHE4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

157688:FVE77 RS03200
gene id: 157688:FVE77_RS03200
uniprot id: A0A510JF58
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

157688:FVE77 RS00265
gene id: 157688:FVE77_RS00265
uniprot id: A0A510JDL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

157688:FVE77 RS09440
gene id: 157688:FVE77_RS09440
uniprot id: A0A510JIS9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

157688:FVE77 RS12120
gene id: 157688:FVE77_RS12120
uniprot id: A0A510JMW9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

157688:FVE77 RS01275
gene id: 157688:FVE77_RS01275
uniprot id: A0A510JEP7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

157688:FVE77 RS01260
gene id: 157688:FVE77_RS01260
uniprot id: A0A510JIA9
names: Similarity
messages: Belongs to the peptidase M29 family.

157688:FVE77 RS11435
gene id: 157688:FVE77_RS11435
uniprot id: A0A510JKA0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

157688:FVE77 RS02105
gene id: 157688:FVE77_RS02105
uniprot id: A0A510JF67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS00515
gene id: 157688:FVE77_RS00515
uniprot id: A0A510JDR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

157688:FVE77 RS10650
gene id: 157688:FVE77_RS10650
uniprot id: A0A510JM42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

157688:FVE77 RS04040
gene id: 157688:FVE77_RS04040
uniprot id: A0A510JJX3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

157688:FVE77 RS07170
gene id: 157688:FVE77_RS07170
uniprot id: A0A510JHK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

157688:FVE77 RS05685
gene id: 157688:FVE77_RS05685
uniprot id: A0A510JJB9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

157688:FVE77 RS05665
gene id: 157688:FVE77_RS05665
uniprot id: A0A510JGS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

157688:FVE77 RS00155
gene id: 157688:FVE77_RS00155
uniprot id: A0A510JE45
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

157688:FVE77 RS08890
gene id: 157688:FVE77_RS08890
uniprot id: A0A510JIN2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

157688:FVE77 RS11335
gene id: 157688:FVE77_RS11335
uniprot id: A0A510JK78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

157688:FVE77 RS04705
gene id: 157688:FVE77_RS04705
uniprot id: A0A510JG76
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

157688:FVE77 RS05640
gene id: 157688:FVE77_RS05640
uniprot id: A0A510JGJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

157688:FVE77 RS04995
gene id: 157688:FVE77_RS04995
uniprot id: A0A510JG68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

157688:FVE77 RS04355
gene id: 157688:FVE77_RS04355
uniprot id: A0A510JG25
names: Subcellular Location Annotation
messages: Membrane

157688:FVE77 RS12090
gene id: 157688:FVE77_RS12090
uniprot id: A0A510JN33
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

157688:FVE77 RS10115
gene id: 157688:FVE77_RS10115
uniprot id: A0A510JJC8
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

157688:FVE77 RS03145
gene id: 157688:FVE77_RS03145
uniprot id: A0A510JF98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

157688:FVE77 RS06030
gene id: 157688:FVE77_RS06030
uniprot id: A0A510JL50
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

157688:FVE77 RS07495
gene id: 157688:FVE77_RS07495
uniprot id: A0A510JHQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.