1553431:MCB1EB RS04455
gene id: 1553431:MCB1EB_RS04455
uniprot id: A0A2Z6EUD0
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

1553431:MCB1EB RS05190
gene id: 1553431:MCB1EB_RS05190
uniprot id: A0A2Z6EUT2
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1553431:MCB1EB RS02815
gene id: 1553431:MCB1EB_RS02815
uniprot id: A0A2Z6ETH6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1553431:MCB1EB RS03475
gene id: 1553431:MCB1EB_RS03475
uniprot id: A0A2Z6EUS4
names: Similarity
messages: Belongs to the UPF0111 family.

1553431:MCB1EB RS00265
gene id: 1553431:MCB1EB_RS00265
uniprot id: A0A2Z6ES38
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1553431:MCB1EB RS08735
gene id: 1553431:MCB1EB_RS08735
uniprot id: A0A2Z6EWN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1553431:MCB1EB RS02895
gene id: 1553431:MCB1EB_RS02895
uniprot id: A0A2Z6ETL7
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS01890
gene id: 1553431:MCB1EB_RS01890
uniprot id: A0A2Z6ESY6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1553431:MCB1EB RS03345
gene id: 1553431:MCB1EB_RS03345
uniprot id: A0A2Z6ETS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1553431:MCB1EB RS10210
gene id: 1553431:MCB1EB_RS10210
uniprot id: A0A2Z6EXG9
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1553431:MCB1EB RS03375
gene id: 1553431:MCB1EB_RS03375
uniprot id: A0A2Z6ETS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1553431:MCB1EB RS00765
gene id: 1553431:MCB1EB_RS00765
uniprot id: A0A2Z6ESD0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1553431:MCB1EB RS10595
gene id: 1553431:MCB1EB_RS10595
uniprot id: A0A2Z6EXP0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1553431:MCB1EB RS03925
gene id: 1553431:MCB1EB_RS03925
uniprot id: A0A2Z6EU11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1553431:MCB1EB RS05295
gene id: 1553431:MCB1EB_RS05295
uniprot id: A0A2Z6EUP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1553431:MCB1EB RS00580
gene id: 1553431:MCB1EB_RS00580
uniprot id: A0A2Z6ES99
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1553431:MCB1EB RS09185
gene id: 1553431:MCB1EB_RS09185
uniprot id: A0A2Z6EXW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1553431:MCB1EB RS11725
gene id: 1553431:MCB1EB_RS11725
uniprot id: A0A2Z6EYG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1553431:MCB1EB RS03495
gene id: 1553431:MCB1EB_RS03495
uniprot id: A0A2Z6ETT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1553431:MCB1EB RS02495
gene id: 1553431:MCB1EB_RS02495
uniprot id: A0A2Z6ETB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1553431:MCB1EB RS11870
gene id: 1553431:MCB1EB_RS11870
uniprot id: A0A2Z6EYI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1553431:MCB1EB RS00585
gene id: 1553431:MCB1EB_RS00585
uniprot id: A0A2Z6ES87
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1553431:MCB1EB RS02440
gene id: 1553431:MCB1EB_RS02440
uniprot id: A0A2Z6ET95
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1553431:MCB1EB RS00840
gene id: 1553431:MCB1EB_RS00840
uniprot id: A0A2Z6ESE5
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1553431:MCB1EB RS01435
gene id: 1553431:MCB1EB_RS01435
uniprot id: A0A2Z6ESQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Homododecamer. Tetramer of trimer.
messages: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.

1553431:MCB1EB RS04660
gene id: 1553431:MCB1EB_RS04660
uniprot id: A0A2Z6EUC5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS00495
gene id: 1553431:MCB1EB_RS00495
uniprot id: A0A2Z6ES83
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1553431:MCB1EB RS10405
gene id: 1553431:MCB1EB_RS10405
uniprot id: A0A2Z6EXK2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1553431:MCB1EB RS10310
gene id: 1553431:MCB1EB_RS10310
uniprot id: A0A2Z6EXJ4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1553431:MCB1EB RS03105
gene id: 1553431:MCB1EB_RS03105
uniprot id: A0A2Z6ETQ2
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

1553431:MCB1EB RS09675
gene id: 1553431:MCB1EB_RS09675
uniprot id: A0A2Z6EX78
names: Function
names: Similarity
messages: Belongs to the ClpA/ClpB family.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1553431:MCB1EB RS06505
gene id: 1553431:MCB1EB_RS06505
uniprot id: A0A2Z6EVI7
names: Similarity
messages: Belongs to the thioredoxin family.

1553431:MCB1EB RS10755
gene id: 1553431:MCB1EB_RS10755
uniprot id: A0A2Z6EXY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1553431:MCB1EB RS11210
gene id: 1553431:MCB1EB_RS11210
uniprot id: A0A2Z6EY85
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1553431:MCB1EB RS09130
gene id: 1553431:MCB1EB_RS09130
uniprot id: A0A2Z6EWU5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1553431:MCB1EB RS01250
gene id: 1553431:MCB1EB_RS01250
uniprot id: A0A2Z6ESM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1553431:MCB1EB RS01335
gene id: 1553431:MCB1EB_RS01335
uniprot id: A0A2Z6ESM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1553431:MCB1EB RS05715
gene id: 1553431:MCB1EB_RS05715
uniprot id: A0A2Z6EV35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1553431:MCB1EB RS04605
gene id: 1553431:MCB1EB_RS04605
uniprot id: A0A2Z6EUF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1553431:MCB1EB RS09510
gene id: 1553431:MCB1EB_RS09510
uniprot id: A0A2Z6EX39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1553431:MCB1EB RS01755
gene id: 1553431:MCB1EB_RS01755
uniprot id: A0A2Z6ESX0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1553431:MCB1EB RS03405
gene id: 1553431:MCB1EB_RS03405
uniprot id: A0A2Z6ETR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1553431:MCB1EB RS09735
gene id: 1553431:MCB1EB_RS09735
uniprot id: A0A2Z6EX74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1553431:MCB1EB RS02830
gene id: 1553431:MCB1EB_RS02830
uniprot id: A0A2Z6ETG1
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1553431:MCB1EB RS11310
gene id: 1553431:MCB1EB_RS11310
uniprot id: A0A2Z6EYA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1553431:MCB1EB RS10245
gene id: 1553431:MCB1EB_RS10245
uniprot id: A0A2Z6EXJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1553431:MCB1EB RS06755
gene id: 1553431:MCB1EB_RS06755
uniprot id: A0A2Z6EVQ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1553431:MCB1EB RS01260
gene id: 1553431:MCB1EB_RS01260
uniprot id: A0A2Z6ESM6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1553431:MCB1EB RS03490
gene id: 1553431:MCB1EB_RS03490
uniprot id: A0A2Z6ETW9
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1553431:MCB1EB RS05150
gene id: 1553431:MCB1EB_RS05150
uniprot id: A0A2Z6EUL7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1553431:MCB1EB RS06980
gene id: 1553431:MCB1EB_RS06980
uniprot id: A0A2Z6EVN9
names: Similarity
messages: Belongs to the GSP E family.

1553431:MCB1EB RS09620
gene id: 1553431:MCB1EB_RS09620
uniprot id: A0A2Z6EX51
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS08740
gene id: 1553431:MCB1EB_RS08740
uniprot id: A0A2Z6EWV6
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS04810
gene id: 1553431:MCB1EB_RS04810
uniprot id: A0A2Z6EUF7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1553431:MCB1EB RS01415
gene id: 1553431:MCB1EB_RS01415
uniprot id: A0A2Z6ESR0
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1553431:MCB1EB RS10240
gene id: 1553431:MCB1EB_RS10240
uniprot id: A0A2Z6EXG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1553431:MCB1EB RS09050
gene id: 1553431:MCB1EB_RS09050
uniprot id: A0A2Z6EX45
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1553431:MCB1EB RS11385
gene id: 1553431:MCB1EB_RS11385
uniprot id: A0A2Z6EYE0
names: Similarity
messages: Belongs to the transposase 7 family.

1553431:MCB1EB RS02855
gene id: 1553431:MCB1EB_RS02855
uniprot id: A0A2Z6ETG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1553431:MCB1EB RS01590
gene id: 1553431:MCB1EB_RS01590
uniprot id: A0A2Z6EST0
names: Cofactor
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1553431:MCB1EB RS07220
gene id: 1553431:MCB1EB_RS07220
uniprot id: A0A2Z6EVT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1553431:MCB1EB RS04180
gene id: 1553431:MCB1EB_RS04180
uniprot id: A0A2Z6EU52
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1553431:MCB1EB RS05595
gene id: 1553431:MCB1EB_RS05595
uniprot id: A0A2Z6EV16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS11285
gene id: 1553431:MCB1EB_RS11285
uniprot id: A0A2Z6EY78
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1553431:MCB1EB RS01345
gene id: 1553431:MCB1EB_RS01345
uniprot id: A0A2Z6ESP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1553431:MCB1EB RS04315
gene id: 1553431:MCB1EB_RS04315
uniprot id: A0A2Z6EU73
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1553431:MCB1EB RS03460
gene id: 1553431:MCB1EB_RS03460
uniprot id: A0A2Z6ETW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1553431:MCB1EB RS03390
gene id: 1553431:MCB1EB_RS03390
uniprot id: A0A2Z6ETR6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

1553431:MCB1EB RS08775
gene id: 1553431:MCB1EB_RS08775
uniprot id: A0A2Z6EXN9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1553431:MCB1EB RS06025
gene id: 1553431:MCB1EB_RS06025
uniprot id: A0A2Z6EV51
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1553431:MCB1EB RS09925
gene id: 1553431:MCB1EB_RS09925
uniprot id: A0A2Z6EXC6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1553431:MCB1EB RS08540
gene id: 1553431:MCB1EB_RS08540
uniprot id: A0A2Z6EWR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1553431:MCB1EB RS00545
gene id: 1553431:MCB1EB_RS00545
uniprot id: A0A2Z6ESA4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1553431:MCB1EB RS08920
gene id: 1553431:MCB1EB_RS08920
uniprot id: A0A2Z6EWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS06880
gene id: 1553431:MCB1EB_RS06880
uniprot id: A0A2Z6EVR1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1553431:MCB1EB RS00990
gene id: 1553431:MCB1EB_RS00990
uniprot id: A0A2Z6ESH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1553431:MCB1EB RS08150
gene id: 1553431:MCB1EB_RS08150
uniprot id: A0A2Z6EVV3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1553431:MCB1EB RS02580
gene id: 1553431:MCB1EB_RS02580
uniprot id: A0A2Z6ETE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1553431:MCB1EB RS01210
gene id: 1553431:MCB1EB_RS01210
uniprot id: A0A2Z6ESM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1553431:MCB1EB RS10735
gene id: 1553431:MCB1EB_RS10735
uniprot id: A0A2Z6EY08
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1553431:MCB1EB RS01065
gene id: 1553431:MCB1EB_RS01065
uniprot id: A0A2Z6ESJ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1553431:MCB1EB RS10990
gene id: 1553431:MCB1EB_RS10990
uniprot id: A0A2Z6EXX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1553431:MCB1EB RS05355
gene id: 1553431:MCB1EB_RS05355
uniprot id: A0A2Z6EUW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1553431:MCB1EB RS10760
gene id: 1553431:MCB1EB_RS10760
uniprot id: A0A2Z6EXS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1553431:MCB1EB RS10345
gene id: 1553431:MCB1EB_RS10345
uniprot id: A0A2Z6EXL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

1553431:MCB1EB RS10605
gene id: 1553431:MCB1EB_RS10605
uniprot id: A0A2Z6EYI5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1553431:MCB1EB RS11005
gene id: 1553431:MCB1EB_RS11005
uniprot id: A0A2Z6EY41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1553431:MCB1EB RS10740
gene id: 1553431:MCB1EB_RS10740
uniprot id: A0A2Z6EXS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1553431:MCB1EB RS10530
gene id: 1553431:MCB1EB_RS10530
uniprot id: A0A2Z6EXN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1553431:MCB1EB RS01530
gene id: 1553431:MCB1EB_RS01530
uniprot id: A0A2Z6ESR6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1553431:MCB1EB RS01295
gene id: 1553431:MCB1EB_RS01295
uniprot id: A0A2Z6ESQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1553431:MCB1EB RS09100
gene id: 1553431:MCB1EB_RS09100
uniprot id: A0A2Z6EX55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1553431:MCB1EB RS09080
gene id: 1553431:MCB1EB_RS09080
uniprot id: A0A2Z6EWT5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS09025
gene id: 1553431:MCB1EB_RS09025
uniprot id: A0A2Z6EWU1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1553431:MCB1EB RS09605
gene id: 1553431:MCB1EB_RS09605
uniprot id: A0A2Z6EX87
names: Similarity
messages: Belongs to the threonine synthase family.

1553431:MCB1EB RS08665
gene id: 1553431:MCB1EB_RS08665
uniprot id: A0A2Z6EWK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1553431:MCB1EB RS00325
gene id: 1553431:MCB1EB_RS00325
uniprot id: A0A2Z6ES44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

1553431:MCB1EB RS11805
gene id: 1553431:MCB1EB_RS11805
uniprot id: A0A2Z6EYG4
names: Similarity
messages: Belongs to the DprA/Smf family.

1553431:MCB1EB RS00245
gene id: 1553431:MCB1EB_RS00245
uniprot id: A0A2Z6ES24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS11205
gene id: 1553431:MCB1EB_RS11205
uniprot id: A0A2Z6EY33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1553431:MCB1EB RS05725
gene id: 1553431:MCB1EB_RS05725
uniprot id: A0A2Z6EV00
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS10855
gene id: 1553431:MCB1EB_RS10855
uniprot id: A0A2Z6EY11
names: Function
names: Similarity
messages: Belongs to the ClpA/ClpB family.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1553431:MCB1EB RS00065
gene id: 1553431:MCB1EB_RS00065
uniprot id: A0A2Z6ES00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1553431:MCB1EB RS11015
gene id: 1553431:MCB1EB_RS11015
uniprot id: A0A2Z6EXX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1553431:MCB1EB RS01935
gene id: 1553431:MCB1EB_RS01935
uniprot id: A0A2Z6ET03
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1553431:MCB1EB RS10715
gene id: 1553431:MCB1EB_RS10715
uniprot id: A0A2Z6EXS4
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS04325
gene id: 1553431:MCB1EB_RS04325
uniprot id: A0A2Z6EUB5
names: Similarity
messages: Belongs to the peptidase U62 family.

1553431:MCB1EB RS09340
gene id: 1553431:MCB1EB_RS09340
uniprot id: A0A2Z6EWY5
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1553431:MCB1EB RS11110
gene id: 1553431:MCB1EB_RS11110
uniprot id: A0A2Z6EY62
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1553431:MCB1EB RS05675
gene id: 1553431:MCB1EB_RS05675
uniprot id: A0A2Z6EUZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS04935
gene id: 1553431:MCB1EB_RS04935
uniprot id: A0A2Z6EUQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1553431:MCB1EB RS04610
gene id: 1553431:MCB1EB_RS04610
uniprot id: A0A2Z6EUB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1553431:MCB1EB RS02565
gene id: 1553431:MCB1EB_RS02565
uniprot id: A0A2Z6ETF7
names: Similarity
messages: Belongs to the YicC/YloC family.

1553431:MCB1EB RS01545
gene id: 1553431:MCB1EB_RS01545
uniprot id: A0A2Z6ESR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS05145
gene id: 1553431:MCB1EB_RS05145
uniprot id: A0A2Z6EUS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1553431:MCB1EB RS00055
gene id: 1553431:MCB1EB_RS00055
uniprot id: A0A2Z6ERZ9
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1553431:MCB1EB RS09930
gene id: 1553431:MCB1EB_RS09930
uniprot id: A0A2Z6EXH8
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1553431:MCB1EB RS01675
gene id: 1553431:MCB1EB_RS01675
uniprot id: A0A2Z6EWY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1553431:MCB1EB RS09015
gene id: 1553431:MCB1EB_RS09015
uniprot id: A0A2Z6EWV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1553431:MCB1EB RS09110
gene id: 1553431:MCB1EB_RS09110
uniprot id: A0A2Z6EWV9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1553431:MCB1EB RS11690
gene id: 1553431:MCB1EB_RS11690
uniprot id: A0A2Z6EY97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1553431:MCB1EB RS00985
gene id: 1553431:MCB1EB_RS00985
uniprot id: A0A2Z6ESH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS09590
gene id: 1553431:MCB1EB_RS09590
uniprot id: A0A2Z6EX32
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1553431:MCB1EB RS00275
gene id: 1553431:MCB1EB_RS00275
uniprot id: A0A2Z6ES36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

1553431:MCB1EB RS00165
gene id: 1553431:MCB1EB_RS00165
uniprot id: A0A2Z6ES21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1553431:MCB1EB RS01235
gene id: 1553431:MCB1EB_RS01235
uniprot id: A0A2Z6ESN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1553431:MCB1EB RS09950
gene id: 1553431:MCB1EB_RS09950
uniprot id: A0A2Z6EXE8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1553431:MCB1EB RS07080
gene id: 1553431:MCB1EB_RS07080
uniprot id: A0A2Z6EVW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1553431:MCB1EB RS00535
gene id: 1553431:MCB1EB_RS00535
uniprot id: A0A2Z6ES76
names: Similarity
messages: Belongs to the peptidase U62 family.

1553431:MCB1EB RS00500
gene id: 1553431:MCB1EB_RS00500
uniprot id: A0A2Z6ES93
names: Similarity
messages: Belongs to the Dps family.

1553431:MCB1EB RS11145
gene id: 1553431:MCB1EB_RS11145
uniprot id: A0A2Z6EY07
names: Similarity
messages: Belongs to the leucine-binding protein family.

1553431:MCB1EB RS10985
gene id: 1553431:MCB1EB_RS10985
uniprot id: A0A2Z6EY58
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1553431:MCB1EB RS05845
gene id: 1553431:MCB1EB_RS05845
uniprot id: A0A2Z6EV18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1553431:MCB1EB RS04290
gene id: 1553431:MCB1EB_RS04290
uniprot id: A0A2Z6EU65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1553431:MCB1EB RS11500
gene id: 1553431:MCB1EB_RS11500
uniprot id: A0A2Z6EYB8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS01185
gene id: 1553431:MCB1EB_RS01185
uniprot id: A0A2Z6ESM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1553431:MCB1EB RS07130
gene id: 1553431:MCB1EB_RS07130
uniprot id: A0A2Z6EVX4
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

1553431:MCB1EB RS06145
gene id: 1553431:MCB1EB_RS06145
uniprot id: A0A2Z6EVC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1553431:MCB1EB RS08645
gene id: 1553431:MCB1EB_RS08645
uniprot id: A0A2Z6EWL8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1553431:MCB1EB RS10320
gene id: 1553431:MCB1EB_RS10320
uniprot id: A0A2Z6EXK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1553431:MCB1EB RS06490
gene id: 1553431:MCB1EB_RS06490
uniprot id: A0A2Z6EWG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1553431:MCB1EB RS08895
gene id: 1553431:MCB1EB_RS08895
uniprot id: A0A2Z6EX16
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1553431:MCB1EB RS03120
gene id: 1553431:MCB1EB_RS03120
uniprot id: A0A2Z6EUK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

1553431:MCB1EB RS04385
gene id: 1553431:MCB1EB_RS04385
uniprot id: A0A2Z6EUB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1553431:MCB1EB RS10930
gene id: 1553431:MCB1EB_RS10930
uniprot id: A0A2Z6EY05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1553431:MCB1EB RS03735
gene id: 1553431:MCB1EB_RS03735
uniprot id: A0A2Z6EUX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1553431:MCB1EB RS06940
gene id: 1553431:MCB1EB_RS06940
uniprot id: A0A2Z6EVQ9
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS09840
gene id: 1553431:MCB1EB_RS09840
uniprot id: A0A2Z6EX81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1553431:MCB1EB RS04440
gene id: 1553431:MCB1EB_RS04440
uniprot id: A0A2Z6EU90
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1553431:MCB1EB RS05155
gene id: 1553431:MCB1EB_RS05155
uniprot id: A0A2Z6EUM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1553431:MCB1EB RS03950
gene id: 1553431:MCB1EB_RS03950
uniprot id: A0A2Z6EU39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS07225
gene id: 1553431:MCB1EB_RS07225
uniprot id: A0A2Z6EVS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1553431:MCB1EB RS08515
gene id: 1553431:MCB1EB_RS08515
uniprot id: A0A2Z6EWJ6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1553431:MCB1EB RS09830
gene id: 1553431:MCB1EB_RS09830
uniprot id: A0A2Z6EXG1
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

1553431:MCB1EB RS02660
gene id: 1553431:MCB1EB_RS02660
uniprot id: A0A2Z6ETE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1553431:MCB1EB RS10780
gene id: 1553431:MCB1EB_RS10780
uniprot id: A0A2Z6EXX4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1553431:MCB1EB RS05630
gene id: 1553431:MCB1EB_RS05630
uniprot id: A0A2Z6EVY9
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1553431:MCB1EB RS10770
gene id: 1553431:MCB1EB_RS10770
uniprot id: A0A2Z6EYI8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1553431:MCB1EB RS10880
gene id: 1553431:MCB1EB_RS10880
uniprot id: A0A2Z6EXZ1
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS01585
gene id: 1553431:MCB1EB_RS01585
uniprot id: A0A2Z6ESS8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1553431:MCB1EB RS08755
gene id: 1553431:MCB1EB_RS08755
uniprot id: A0A2Z6EWQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1553431:MCB1EB RS09495
gene id: 1553431:MCB1EB_RS09495
uniprot id: A0A2Z6EX60
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS10725
gene id: 1553431:MCB1EB_RS10725
uniprot id: A0A2Z6EXT9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1553431:MCB1EB RS05160
gene id: 1553431:MCB1EB_RS05160
uniprot id: A0A2Z6EUS3
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1553431:MCB1EB RS00800
gene id: 1553431:MCB1EB_RS00800
uniprot id: A0A2Z6ESC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1553431:MCB1EB RS00705
gene id: 1553431:MCB1EB_RS00705
uniprot id: A0A2Z6ESC1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1553431:MCB1EB RS06450
gene id: 1553431:MCB1EB_RS06450
uniprot id: A0A2Z6EVH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1553431:MCB1EB RS11580
gene id: 1553431:MCB1EB_RS11580
uniprot id: A0A2Z6EY99
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1553431:MCB1EB RS10800
gene id: 1553431:MCB1EB_RS10800
uniprot id: A0A2Z6EXV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1553431:MCB1EB RS07935
gene id: 1553431:MCB1EB_RS07935
uniprot id: A0A2Z6EW71
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1553431:MCB1EB RS05810
gene id: 1553431:MCB1EB_RS05810
uniprot id: A0A2Z6EV60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS07230
gene id: 1553431:MCB1EB_RS07230
uniprot id: A0A2Z6EWU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1553431:MCB1EB RS09665
gene id: 1553431:MCB1EB_RS09665
uniprot id: A0A2Z6EX66
names: Similarity
messages: Belongs to the VgrG protein family.

1553431:MCB1EB RS09740
gene id: 1553431:MCB1EB_RS09740
uniprot id: A0A2Z6EX63
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1553431:MCB1EB RS10490
gene id: 1553431:MCB1EB_RS10490
uniprot id: A0A2Z6EXM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1553431:MCB1EB RS05780
gene id: 1553431:MCB1EB_RS05780
uniprot id: A0A2Z6EW19
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1553431:MCB1EB RS04125
gene id: 1553431:MCB1EB_RS04125
uniprot id: A0A2Z6EU45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1553431:MCB1EB RS05165
gene id: 1553431:MCB1EB_RS05165
uniprot id: A0A2Z6EUR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1553431:MCB1EB RS04445
gene id: 1553431:MCB1EB_RS04445
uniprot id: A0A2Z6EU88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1553431:MCB1EB RS00415
gene id: 1553431:MCB1EB_RS00415
uniprot id: A0A2Z6ES64
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1553431:MCB1EB RS11065
gene id: 1553431:MCB1EB_RS11065
uniprot id: A0A2Z6EXY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1553431:MCB1EB RS06900
gene id: 1553431:MCB1EB_RS06900
uniprot id: A0A2Z6EVT3
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1553431:MCB1EB RS10475
gene id: 1553431:MCB1EB_RS10475
uniprot id: A0A2Z6EXR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1553431:MCB1EB RS05565
gene id: 1553431:MCB1EB_RS05565
uniprot id: A0A2Z6EV07
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1553431:MCB1EB RS10905
gene id: 1553431:MCB1EB_RS10905
uniprot id: A0A2Z6EY21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1553431:MCB1EB RS05800
gene id: 1553431:MCB1EB_RS05800
uniprot id: A0A2Z6EV08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1553431:MCB1EB RS05790
gene id: 1553431:MCB1EB_RS05790
uniprot id: A0A2Z6EV52
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1553431:MCB1EB RS03230
gene id: 1553431:MCB1EB_RS03230
uniprot id: A0A2Z6ETP6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1553431:MCB1EB RS01195
gene id: 1553431:MCB1EB_RS01195
uniprot id: A0A2Z6ESL2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1553431:MCB1EB RS06960
gene id: 1553431:MCB1EB_RS06960
uniprot id: A0A2Z6EWP0
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1553431:MCB1EB RS03295
gene id: 1553431:MCB1EB_RS03295
uniprot id: A0A2Z6ETR8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1553431:MCB1EB RS08930
gene id: 1553431:MCB1EB_RS08930
uniprot id: A0A2Z6EWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

1553431:MCB1EB RS10680
gene id: 1553431:MCB1EB_RS10680
uniprot id: A0A2Z6EXZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1553431:MCB1EB RS00820
gene id: 1553431:MCB1EB_RS00820
uniprot id: A0A2Z6ESF0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1553431:MCB1EB RS00780
gene id: 1553431:MCB1EB_RS00780
uniprot id: A0A2Z6ESD1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1553431:MCB1EB RS10325
gene id: 1553431:MCB1EB_RS10325
uniprot id: A0A2Z6EXN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1553431:MCB1EB RS09190
gene id: 1553431:MCB1EB_RS09190
uniprot id: A0A2Z6EX06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1553431:MCB1EB RS05635
gene id: 1553431:MCB1EB_RS05635
uniprot id: A0A2Z6EV38
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1553431:MCB1EB RS06340
gene id: 1553431:MCB1EB_RS06340
uniprot id: A0A2Z6EVB4
names: Similarity
messages: Belongs to the peptidase C40 family.

1553431:MCB1EB RS12190
gene id: 1553431:MCB1EB_RS12190
uniprot id: A0A2Z6EVC0
names: Similarity
messages: Belongs to the BolA/IbaG family.

1553431:MCB1EB RS01785
gene id: 1553431:MCB1EB_RS01785
uniprot id: A0A2Z6ESY7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS09790
gene id: 1553431:MCB1EB_RS09790
uniprot id: A0A2Z6EX72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS08715
gene id: 1553431:MCB1EB_RS08715
uniprot id: A0A2Z6EWN6
names: Similarity
messages: Belongs to the UPF0246 family.

1553431:MCB1EB RS05070
gene id: 1553431:MCB1EB_RS05070
uniprot id: A0A2Z6EUM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1553431:MCB1EB RS03580
gene id: 1553431:MCB1EB_RS03580
uniprot id: A0A2Z6ETT7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1553431:MCB1EB RS10955
gene id: 1553431:MCB1EB_RS10955
uniprot id: A0A2Z6EY31
names: Similarity
messages: Belongs to the peptidase S41A family.

1553431:MCB1EB RS10300
gene id: 1553431:MCB1EB_RS10300
uniprot id: A0A2Z6EXP7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1553431:MCB1EB RS09565
gene id: 1553431:MCB1EB_RS09565
uniprot id: A0A2Z6EX40
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1553431:MCB1EB RS05730
gene id: 1553431:MCB1EB_RS05730
uniprot id: A0A2Z6EW09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1553431:MCB1EB RS03020
gene id: 1553431:MCB1EB_RS03020
uniprot id: A0A2Z6EUI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

1553431:MCB1EB RS05820
gene id: 1553431:MCB1EB_RS05820
uniprot id: A0A2Z6EV21
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS03400
gene id: 1553431:MCB1EB_RS03400
uniprot id: A0A2Z6ETV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1553431:MCB1EB RS01300
gene id: 1553431:MCB1EB_RS01300
uniprot id: A0A2Z6ESP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1553431:MCB1EB RS10950
gene id: 1553431:MCB1EB_RS10950
uniprot id: A0A2Z6EXY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1553431:MCB1EB RS11645
gene id: 1553431:MCB1EB_RS11645
uniprot id: A0A2Z6EY86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1553431:MCB1EB RS01505
gene id: 1553431:MCB1EB_RS01505
uniprot id: A0A2Z6ESS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS02940
gene id: 1553431:MCB1EB_RS02940
uniprot id: A0A2Z6ETJ9
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1553431:MCB1EB RS10445
gene id: 1553431:MCB1EB_RS10445
uniprot id: A0A2Z6EXN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1553431:MCB1EB RS05570
gene id: 1553431:MCB1EB_RS05570
uniprot id: A0A2Z6EUU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1553431:MCB1EB RS06005
gene id: 1553431:MCB1EB_RS06005
uniprot id: A0A2Z6EV32
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1553431:MCB1EB RS04285
gene id: 1553431:MCB1EB_RS04285
uniprot id: A0A2Z6EU69
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1553431:MCB1EB RS01380
gene id: 1553431:MCB1EB_RS01380
uniprot id: A0A2Z6ESP2
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1553431:MCB1EB RS04750
gene id: 1553431:MCB1EB_RS04750
uniprot id: A0A2Z6EUH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

1553431:MCB1EB RS02555
gene id: 1553431:MCB1EB_RS02555
uniprot id: A0A2Z6ETB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1553431:MCB1EB RS08620
gene id: 1553431:MCB1EB_RS08620
uniprot id: A0A2Z6EXL0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1553431:MCB1EB RS07165
gene id: 1553431:MCB1EB_RS07165
uniprot id: A0A2Z6EVS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1553431:MCB1EB RS01395
gene id: 1553431:MCB1EB_RS01395
uniprot id: A0A2Z6ESQ1
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS00155
gene id: 1553431:MCB1EB_RS00155
uniprot id: A0A2Z6ES15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1553431:MCB1EB RS09530
gene id: 1553431:MCB1EB_RS09530
uniprot id: A0A2Z6EX42
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS04355
gene id: 1553431:MCB1EB_RS04355
uniprot id: A0A2Z6EUB4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1553431:MCB1EB RS03825
gene id: 1553431:MCB1EB_RS03825
uniprot id: A0A2Z6ETZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1553431:MCB1EB RS08990
gene id: 1553431:MCB1EB_RS08990
uniprot id: A0A2Z6EWX3
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

1553431:MCB1EB RS03060
gene id: 1553431:MCB1EB_RS03060
uniprot id: A0A2Z6ETJ8
names: Similarity
messages: Belongs to the SctE/SipB/YopB family.

1553431:MCB1EB RS11605
gene id: 1553431:MCB1EB_RS11605
uniprot id: A0A2Z6EYB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1553431:MCB1EB RS11775
gene id: 1553431:MCB1EB_RS11775
uniprot id: A0A2Z6EYH2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS03470
gene id: 1553431:MCB1EB_RS03470
uniprot id: A0A2Z6ETS1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1553431:MCB1EB RS10335
gene id: 1553431:MCB1EB_RS10335
uniprot id: A0A2Z6EXI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1553431:MCB1EB RS00945
gene id: 1553431:MCB1EB_RS00945
uniprot id: A0A2Z6ESG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

1553431:MCB1EB RS12375
gene id: 1553431:MCB1EB_RS12375
uniprot id: A0A2Z6EUZ3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1553431:MCB1EB RS09720
gene id: 1553431:MCB1EB_RS09720
uniprot id: A0A2Z6EX68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1553431:MCB1EB RS03720
gene id: 1553431:MCB1EB_RS03720
uniprot id: A0A2Z6ETW3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1553431:MCB1EB RS06030
gene id: 1553431:MCB1EB_RS06030
uniprot id: A0A2Z6EVA2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS04265
gene id: 1553431:MCB1EB_RS04265
uniprot id: A0A2Z6EU64
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1553431:MCB1EB RS03175
gene id: 1553431:MCB1EB_RS03175
uniprot id: A0A2Z6ETN6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1553431:MCB1EB RS01290
gene id: 1553431:MCB1EB_RS01290
uniprot id: A0A2Z6ESN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1553431:MCB1EB RS07210
gene id: 1553431:MCB1EB_RS07210
uniprot id: A0A2Z6EVW4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1553431:MCB1EB RS04475
gene id: 1553431:MCB1EB_RS04475
uniprot id: A0A2Z6EUB8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1553431:MCB1EB RS08685
gene id: 1553431:MCB1EB_RS08685
uniprot id: A0A2Z6EWU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1553431:MCB1EB RS04035
gene id: 1553431:MCB1EB_RS04035
uniprot id: A0A2Z6EV39
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS11170
gene id: 1553431:MCB1EB_RS11170
uniprot id: A0A2Z6EY06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1553431:MCB1EB RS00250
gene id: 1553431:MCB1EB_RS00250
uniprot id: A0A2Z6ES32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1553431:MCB1EB RS02950
gene id: 1553431:MCB1EB_RS02950
uniprot id: A0A2Z6ETM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

1553431:MCB1EB RS05205
gene id: 1553431:MCB1EB_RS05205
uniprot id: A0A2Z6EUT1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1553431:MCB1EB RS11785
gene id: 1553431:MCB1EB_RS11785
uniprot id: A0A2Z6EYC0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1553431:MCB1EB RS06475
gene id: 1553431:MCB1EB_RS06475
uniprot id: A0A2Z6EVI1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1553431:MCB1EB RS10435
gene id: 1553431:MCB1EB_RS10435
uniprot id: A0A2Z6EXK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1553431:MCB1EB RS11570
gene id: 1553431:MCB1EB_RS11570
uniprot id: A0A2Z6EY83
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1553431:MCB1EB RS03635
gene id: 1553431:MCB1EB_RS03635
uniprot id: A0A2Z6EUV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

1553431:MCB1EB RS10260
gene id: 1553431:MCB1EB_RS10260
uniprot id: A0A2Z6EXI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1553431:MCB1EB RS04465
gene id: 1553431:MCB1EB_RS04465
uniprot id: A0A2Z6EUD9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1553431:MCB1EB RS02900
gene id: 1553431:MCB1EB_RS02900
uniprot id: A0A2Z6ETH4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1553431:MCB1EB RS01405
gene id: 1553431:MCB1EB_RS01405
uniprot id: A0A2Z6ESR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1553431:MCB1EB RS07245
gene id: 1553431:MCB1EB_RS07245
uniprot id: A0A2Z6EVZ5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1553431:MCB1EB RS09295
gene id: 1553431:MCB1EB_RS09295
uniprot id: A0A2Z6EWX6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1553431:MCB1EB RS11000
gene id: 1553431:MCB1EB_RS11000
uniprot id: A0A2Z6EXZ3
names: Similarity
messages: Belongs to the UPF0434 family.

1553431:MCB1EB RS07240
gene id: 1553431:MCB1EB_RS07240
uniprot id: A0A2Z6EVT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1553431:MCB1EB RS02970
gene id: 1553431:MCB1EB_RS02970
uniprot id: A0A2Z6ETK1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1553431:MCB1EB RS10670
gene id: 1553431:MCB1EB_RS10670
uniprot id: A0A2Z6EXS9
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS11050
gene id: 1553431:MCB1EB_RS11050
uniprot id: A0A2Z6EY01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1553431:MCB1EB RS03520
gene id: 1553431:MCB1EB_RS03520
uniprot id: A0A2Z6ETS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1553431:MCB1EB RS06175
gene id: 1553431:MCB1EB_RS06175
uniprot id: A0A2Z6EVD2
names: Similarity
messages: Belongs to the peptidase S11 family.

1553431:MCB1EB RS03955
gene id: 1553431:MCB1EB_RS03955
uniprot id: A0A2Z6EU08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS11800
gene id: 1553431:MCB1EB_RS11800
uniprot id: A0A2Z6EYF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1553431:MCB1EB RS00160
gene id: 1553431:MCB1EB_RS00160
uniprot id: A0A2Z6ES17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1553431:MCB1EB RS05775
gene id: 1553431:MCB1EB_RS05775
uniprot id: A0A2Z6EV10
names: Similarity
messages: Belongs to the pirin family.

1553431:MCB1EB RS03095
gene id: 1553431:MCB1EB_RS03095
uniprot id: A0A2Z6ETN0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1553431:MCB1EB RS01945
gene id: 1553431:MCB1EB_RS01945
uniprot id: A0A2Z6ET33
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS03225
gene id: 1553431:MCB1EB_RS03225
uniprot id: A0A2Z6ETP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1553431:MCB1EB RS09725
gene id: 1553431:MCB1EB_RS09725
uniprot id: A0A2Z6EX89
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1553431:MCB1EB RS00960
gene id: 1553431:MCB1EB_RS00960
uniprot id: A0A2Z6ESG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

1553431:MCB1EB RS01870
gene id: 1553431:MCB1EB_RS01870
uniprot id: A0A2Z6ESY8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1553431:MCB1EB RS03600
gene id: 1553431:MCB1EB_RS03600
uniprot id: A0A2Z6ETX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1553431:MCB1EB RS09175
gene id: 1553431:MCB1EB_RS09175
uniprot id: A0A2Z6EWX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1553431:MCB1EB RS09160
gene id: 1553431:MCB1EB_RS09160
uniprot id: A0A2Z6EWW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS06085
gene id: 1553431:MCB1EB_RS06085
uniprot id: A0A2Z6EVA3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1553431:MCB1EB RS06480
gene id: 1553431:MCB1EB_RS06480
uniprot id: A0A2Z6EVC7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1553431:MCB1EB RS00455
gene id: 1553431:MCB1EB_RS00455
uniprot id: A0A2Z6ES77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1553431:MCB1EB RS08565
gene id: 1553431:MCB1EB_RS08565
uniprot id: A0A2Z6EWK5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS06405
gene id: 1553431:MCB1EB_RS06405
uniprot id: A0A2Z6EVF3
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1553431:MCB1EB RS00720
gene id: 1553431:MCB1EB_RS00720
uniprot id: A0A2Z6ESB8
names: Similarity
messages: Belongs to the barstar family.

1553431:MCB1EB RS00400
gene id: 1553431:MCB1EB_RS00400
uniprot id: A0A2Z6ES58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1553431:MCB1EB RS02405
gene id: 1553431:MCB1EB_RS02405
uniprot id: A0A2Z6ET92
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS00005
gene id: 1553431:MCB1EB_RS00005
uniprot id: A0A2Z6ERX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1553431:MCB1EB RS04725
gene id: 1553431:MCB1EB_RS04725
uniprot id: A0A2Z6EUI3
names: Similarity
messages: Belongs to the PGI/PMI family.

1553431:MCB1EB RS00805
gene id: 1553431:MCB1EB_RS00805
uniprot id: A0A2Z6ESF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1553431:MCB1EB RS08975
gene id: 1553431:MCB1EB_RS08975
uniprot id: A0A2Z6EWT0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1553431:MCB1EB RS01165
gene id: 1553431:MCB1EB_RS01165
uniprot id: A0A2Z6ESK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1553431:MCB1EB RS09610
gene id: 1553431:MCB1EB_RS09610
uniprot id: A0A2Z6EXF1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1553431:MCB1EB RS00530
gene id: 1553431:MCB1EB_RS00530
uniprot id: A0A2Z6ES92
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1553431:MCB1EB RS01520
gene id: 1553431:MCB1EB_RS01520
uniprot id: A0A2Z6ESS5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1553431:MCB1EB RS08745
gene id: 1553431:MCB1EB_RS08745
uniprot id: A0A2Z6EWP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1553431:MCB1EB RS11225
gene id: 1553431:MCB1EB_RS11225
uniprot id: A0A2Z6EYQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1553431:MCB1EB RS01800
gene id: 1553431:MCB1EB_RS01800
uniprot id: A0A2Z6ESZ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1553431:MCB1EB RS01605
gene id: 1553431:MCB1EB_RS01605
uniprot id: A0A2Z6ESU0
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1553431:MCB1EB RS01710
gene id: 1553431:MCB1EB_RS01710
uniprot id: A0A2Z6ESW6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1553431:MCB1EB RS06865
gene id: 1553431:MCB1EB_RS06865
uniprot id: A0A2Z6EVL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS11550
gene id: 1553431:MCB1EB_RS11550
uniprot id: A0A2Z6EYA1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1553431:MCB1EB RS04435
gene id: 1553431:MCB1EB_RS04435
uniprot id: A0A2Z6EUC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1553431:MCB1EB RS04295
gene id: 1553431:MCB1EB_RS04295
uniprot id: A0A2Z6EV86
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1553431:MCB1EB RS01275
gene id: 1553431:MCB1EB_RS01275
uniprot id: A0A2Z6ESL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1553431:MCB1EB RS07200
gene id: 1553431:MCB1EB_RS07200
uniprot id: A0A2Z6EVV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1553431:MCB1EB RS01320
gene id: 1553431:MCB1EB_RS01320
uniprot id: A0A2Z6ESM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1553431:MCB1EB RS09555
gene id: 1553431:MCB1EB_RS09555
uniprot id: A0A2Z6EXE2
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1553431:MCB1EB RS03540
gene id: 1553431:MCB1EB_RS03540
uniprot id: A0A2Z6ETU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

1553431:MCB1EB RS11620
gene id: 1553431:MCB1EB_RS11620
uniprot id: A0A2Z6EY94
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1553431:MCB1EB RS10465
gene id: 1553431:MCB1EB_RS10465
uniprot id: A0A2Z6EYH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1553431:MCB1EB RS10395
gene id: 1553431:MCB1EB_RS10395
uniprot id: A0A2Z6EXM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1553431:MCB1EB RS10580
gene id: 1553431:MCB1EB_RS10580
uniprot id: A0A2Z6EXP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS02525
gene id: 1553431:MCB1EB_RS02525
uniprot id: A0A2Z6ETF1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1553431:MCB1EB RS10265
gene id: 1553431:MCB1EB_RS10265
uniprot id: A0A2Z6EYG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1553431:MCB1EB RS08395
gene id: 1553431:MCB1EB_RS08395
uniprot id: A0A2Z6EWI9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1553431:MCB1EB RS09140
gene id: 1553431:MCB1EB_RS09140
uniprot id: A0A2Z6EWZ9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1553431:MCB1EB RS09550
gene id: 1553431:MCB1EB_RS09550
uniprot id: A0A2Z6EX77
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1553431:MCB1EB RS00710
gene id: 1553431:MCB1EB_RS00710
uniprot id: A0A2Z6ESB7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1553431:MCB1EB RS11175
gene id: 1553431:MCB1EB_RS11175
uniprot id: A0A2Z6EYP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1553431:MCB1EB RS04495
gene id: 1553431:MCB1EB_RS04495
uniprot id: A0A2Z6EUA5
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1553431:MCB1EB RS11635
gene id: 1553431:MCB1EB_RS11635
uniprot id: A0A2Z6EYF7
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS10550
gene id: 1553431:MCB1EB_RS10550
uniprot id: A0A2Z6EXN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1553431:MCB1EB RS09030
gene id: 1553431:MCB1EB_RS09030
uniprot id: A0A2Z6EWS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS00465
gene id: 1553431:MCB1EB_RS00465
uniprot id: A0A2Z6ES78
names: Similarity
messages: Belongs to the malic enzymes family.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1553431:MCB1EB RS09040
gene id: 1553431:MCB1EB_RS09040
uniprot id: A0A2Z6EWY2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1553431:MCB1EB RS04795
gene id: 1553431:MCB1EB_RS04795
uniprot id: A0A2Z6EUG8
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS05035
gene id: 1553431:MCB1EB_RS05035
uniprot id: A0A2Z6EUK4
names: Subcellular Location Annotation
messages: Cytoplasm

1553431:MCB1EB RS09795
gene id: 1553431:MCB1EB_RS09795
uniprot id: A0A2Z6EY73
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS00460
gene id: 1553431:MCB1EB_RS00460
uniprot id: A0A2Z6ES82
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS04245
gene id: 1553431:MCB1EB_RS04245
uniprot id: A0A2Z6EV76
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1553431:MCB1EB RS00790
gene id: 1553431:MCB1EB_RS00790
uniprot id: A0A2Z6ESD4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1553431:MCB1EB RS10315
gene id: 1553431:MCB1EB_RS10315
uniprot id: A0A2Z6EYG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1553431:MCB1EB RS10940
gene id: 1553431:MCB1EB_RS10940
uniprot id: A0A2Z6EXW8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1553431:MCB1EB RS03250
gene id: 1553431:MCB1EB_RS03250
uniprot id: A0A2Z6ETQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1553431:MCB1EB RS01550
gene id: 1553431:MCB1EB_RS01550
uniprot id: A0A2Z6EST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1553431:MCB1EB RS05650
gene id: 1553431:MCB1EB_RS05650
uniprot id: A0A2Z6EUW9
names: Similarity
messages: Belongs to the HesB/IscA family.

1553431:MCB1EB RS04140
gene id: 1553431:MCB1EB_RS04140
uniprot id: A0A2Z6EU71
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1553431:MCB1EB RS10810
gene id: 1553431:MCB1EB_RS10810
uniprot id: A0A2Z6EXT0
names: Similarity
messages: Belongs to the peptidase M16 family.

1553431:MCB1EB RS05710
gene id: 1553431:MCB1EB_RS05710
uniprot id: A0A2Z6EV28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1553431:MCB1EB RS08965
gene id: 1553431:MCB1EB_RS08965
uniprot id: A0A2Z6EWU2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1553431:MCB1EB RS04240
gene id: 1553431:MCB1EB_RS04240
uniprot id: A0A2Z6EU56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1553431:MCB1EB RS02575
gene id: 1553431:MCB1EB_RS02575
uniprot id: A0A2Z6ETD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1553431:MCB1EB RS02465
gene id: 1553431:MCB1EB_RS02465
uniprot id: A0A2Z6ETC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1553431:MCB1EB RS02025
gene id: 1553431:MCB1EB_RS02025
uniprot id: A0A2Z6EVV3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1553431:MCB1EB RS08525
gene id: 1553431:MCB1EB_RS08525
uniprot id: A0A2Z6EXJ1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS11115
gene id: 1553431:MCB1EB_RS11115
uniprot id: A0A2Z6EXZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1553431:MCB1EB RS02670
gene id: 1553431:MCB1EB_RS02670
uniprot id: A0A2Z6ETF2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1553431:MCB1EB RS01240
gene id: 1553431:MCB1EB_RS01240
uniprot id: A0A2Z6ESL4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1553431:MCB1EB RS00365
gene id: 1553431:MCB1EB_RS00365
uniprot id: A0A2Z6ES53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1553431:MCB1EB RS02610
gene id: 1553431:MCB1EB_RS02610
uniprot id: A0A2Z6ETD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1553431:MCB1EB RS10095
gene id: 1553431:MCB1EB_RS10095
uniprot id: A0A2Z6EXK8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1553431:MCB1EB RS03935
gene id: 1553431:MCB1EB_RS03935
uniprot id: A0A2Z6EV15
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

1553431:MCB1EB RS04680
gene id: 1553431:MCB1EB_RS04680
uniprot id: A0A2Z6EUH4
names: Similarity
messages: Belongs to the DEAD box helicase family.

1553431:MCB1EB RS10295
gene id: 1553431:MCB1EB_RS10295
uniprot id: A0A2Z6EXK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

1553431:MCB1EB RS10430
gene id: 1553431:MCB1EB_RS10430
uniprot id: A0A2Z6EXV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1553431:MCB1EB RS05440
gene id: 1553431:MCB1EB_RS05440
uniprot id: A0A2Z6EUZ2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1553431:MCB1EB RS04320
gene id: 1553431:MCB1EB_RS04320
uniprot id: A0A2Z6EU89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1553431:MCB1EB RS03820
gene id: 1553431:MCB1EB_RS03820
uniprot id: A0A2Z6EU25
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1553431:MCB1EB RS08555
gene id: 1553431:MCB1EB_RS08555
uniprot id: A0A2Z6EWL9
names: Similarity
messages: Belongs to the RecJ family.

1553431:MCB1EB RS03385
gene id: 1553431:MCB1EB_RS03385
uniprot id: A0A2Z6ETV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1553431:MCB1EB RS00185
gene id: 1553431:MCB1EB_RS00185
uniprot id: A0A2Z6ES23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1553431:MCB1EB RS11035
gene id: 1553431:MCB1EB_RS11035
uniprot id: A0A2Z6EY68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1553431:MCB1EB RS04790
gene id: 1553431:MCB1EB_RS04790
uniprot id: A0A2Z6EUG1
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS09525
gene id: 1553431:MCB1EB_RS09525
uniprot id: A0A2Z6EX90
names: Similarity
messages: Belongs to the TrpF family.

1553431:MCB1EB RS04505
gene id: 1553431:MCB1EB_RS04505
uniprot id: A0A2Z6EUD7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1553431:MCB1EB RS02840
gene id: 1553431:MCB1EB_RS02840
uniprot id: A0A2Z6ETI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS11515
gene id: 1553431:MCB1EB_RS11515
uniprot id: A0A2Z6EYA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS09115
gene id: 1553431:MCB1EB_RS09115
uniprot id: A0A2Z6EWX2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1553431:MCB1EB RS05620
gene id: 1553431:MCB1EB_RS05620
uniprot id: A0A2Z6EUV5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1553431:MCB1EB RS01525
gene id: 1553431:MCB1EB_RS01525
uniprot id: A0A2Z6ESS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1553431:MCB1EB RS09545
gene id: 1553431:MCB1EB_RS09545
uniprot id: A0A2Z6EX70
names: Similarity
messages: Belongs to the citrate synthase family.

1553431:MCB1EB RS05095
gene id: 1553431:MCB1EB_RS05095
uniprot id: A0A2Z6EUK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1553431:MCB1EB RS00240
gene id: 1553431:MCB1EB_RS00240
uniprot id: A0A2Z6ES33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1553431:MCB1EB RS01535
gene id: 1553431:MCB1EB_RS01535
uniprot id: A0A2Z6ESR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1553431:MCB1EB RS08670
gene id: 1553431:MCB1EB_RS08670
uniprot id: A0A2Z6EXL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1553431:MCB1EB RS02450
gene id: 1553431:MCB1EB_RS02450
uniprot id: A0A2Z6ETD8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1553431:MCB1EB RS10160
gene id: 1553431:MCB1EB_RS10160
uniprot id: A0A2Z6EXF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1553431:MCB1EB RS03280
gene id: 1553431:MCB1EB_RS03280
uniprot id: A0A2Z6ETQ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1553431:MCB1EB RS05600
gene id: 1553431:MCB1EB_RS05600
uniprot id: A0A2Z6EUV9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1553431:MCB1EB RS01180
gene id: 1553431:MCB1EB_RS01180
uniprot id: A0A2Z6ESK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1553431:MCB1EB RS02355
gene id: 1553431:MCB1EB_RS02355
uniprot id: A0A2Z6ET82
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS06125
gene id: 1553431:MCB1EB_RS06125
uniprot id: A0A2Z6EVC1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1553431:MCB1EB RS00195
gene id: 1553431:MCB1EB_RS00195
uniprot id: A0A2Z6ES19
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1553431:MCB1EB RS05660
gene id: 1553431:MCB1EB_RS05660
uniprot id: A0A2Z6EV19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1553431:MCB1EB RS04250
gene id: 1553431:MCB1EB_RS04250
uniprot id: A0A2Z6EU95
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1553431:MCB1EB RS06555
gene id: 1553431:MCB1EB_RS06555
uniprot id: A0A2Z6EVL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

1553431:MCB1EB RS11650
gene id: 1553431:MCB1EB_RS11650
uniprot id: A0A2Z6EYX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1553431:MCB1EB RS03810
gene id: 1553431:MCB1EB_RS03810
uniprot id: A0A2Z6EU07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1553431:MCB1EB RS01445
gene id: 1553431:MCB1EB_RS01445
uniprot id: A0A2Z6ESR8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS03740
gene id: 1553431:MCB1EB_RS03740
uniprot id: A0A2Z6ETZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1553431:MCB1EB RS06020
gene id: 1553431:MCB1EB_RS06020
uniprot id: A0A2Z6EVC4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1553431:MCB1EB RS11070
gene id: 1553431:MCB1EB_RS11070
uniprot id: A0A2Z6EXY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1553431:MCB1EB RS04395
gene id: 1553431:MCB1EB_RS04395
uniprot id: A0A2Z6EU82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1553431:MCB1EB RS10970
gene id: 1553431:MCB1EB_RS10970
uniprot id: A0A2Z6EYL9
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1553431:MCB1EB RS02455
gene id: 1553431:MCB1EB_RS02455
uniprot id: A0A2Z6ET99
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1553431:MCB1EB RS08780
gene id: 1553431:MCB1EB_RS08780
uniprot id: A0A2Z6EWT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1553431:MCB1EB RS05320
gene id: 1553431:MCB1EB_RS05320
uniprot id: A0A2Z6EVS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

1553431:MCB1EB RS10425
gene id: 1553431:MCB1EB_RS10425
uniprot id: A0A2Z6EXQ6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1553431:MCB1EB RS11255
gene id: 1553431:MCB1EB_RS11255
uniprot id: A0A2Z6EY40
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1553431:MCB1EB RS04310
gene id: 1553431:MCB1EB_RS04310
uniprot id: A0A2Z6EUB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1553431:MCB1EB RS02825
gene id: 1553431:MCB1EB_RS02825
uniprot id: A0A2Z6ETK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1553431:MCB1EB RS06945
gene id: 1553431:MCB1EB_RS06945
uniprot id: A0A2Z6EVS7
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS00285
gene id: 1553431:MCB1EB_RS00285
uniprot id: A0A2Z6ES40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1553431:MCB1EB RS11680
gene id: 1553431:MCB1EB_RS11680
uniprot id: A0A2Z6EYB9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1553431:MCB1EB RS04190
gene id: 1553431:MCB1EB_RS04190
uniprot id: A0A2Z6EV63
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1553431:MCB1EB RS08810
gene id: 1553431:MCB1EB_RS08810
uniprot id: A0A2Z6EWR9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1553431:MCB1EB RS00795
gene id: 1553431:MCB1EB_RS00795
uniprot id: A0A2Z6ESD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1553431:MCB1EB RS10820
gene id: 1553431:MCB1EB_RS10820
uniprot id: A0A2Z6EYI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1553431:MCB1EB RS11420
gene id: 1553431:MCB1EB_RS11420
uniprot id: A0A2Z6EYC3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1553431:MCB1EB RS06045
gene id: 1553431:MCB1EB_RS06045
uniprot id: A0A2Z6EV95
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1553431:MCB1EB RS08690
gene id: 1553431:MCB1EB_RS08690
uniprot id: A0A2Z6EWN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1553431:MCB1EB RS02920
gene id: 1553431:MCB1EB_RS02920
uniprot id: A0A2Z6ETJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1553431:MCB1EB RS02400
gene id: 1553431:MCB1EB_RS02400
uniprot id: A0A2Z6ETC4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1553431:MCB1EB RS06895
gene id: 1553431:MCB1EB_RS06895
uniprot id: A0A2Z6EWN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1553431:MCB1EB RS11085
gene id: 1553431:MCB1EB_RS11085
uniprot id: A0A2Z6EY34
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1553431:MCB1EB RS03360
gene id: 1553431:MCB1EB_RS03360
uniprot id: A0A2Z6ETP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1553431:MCB1EB RS04625
gene id: 1553431:MCB1EB_RS04625
uniprot id: A0A2Z6EUF4
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS05180
gene id: 1553431:MCB1EB_RS05180
uniprot id: A0A2Z6EUU7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1553431:MCB1EB RS01155
gene id: 1553431:MCB1EB_RS01155
uniprot id: A0A2Z6ESL7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1553431:MCB1EB RS05605
gene id: 1553431:MCB1EB_RS05605
uniprot id: A0A2Z6EUX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1553431:MCB1EB RS00995
gene id: 1553431:MCB1EB_RS00995
uniprot id: A0A2Z6ESH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS00830
gene id: 1553431:MCB1EB_RS00830
uniprot id: A0A2Z6ESE4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1553431:MCB1EB RS10375
gene id: 1553431:MCB1EB_RS10375
uniprot id: A0A2Z6EXP3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS08785
gene id: 1553431:MCB1EB_RS08785
uniprot id: A0A2Z6EWP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1553431:MCB1EB RS05005
gene id: 1553431:MCB1EB_RS05005
uniprot id: A0A2Z6EUP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1553431:MCB1EB RS09095
gene id: 1553431:MCB1EB_RS09095
uniprot id: A0A2Z6EWV7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1553431:MCB1EB RS09845
gene id: 1553431:MCB1EB_RS09845
uniprot id: A0A2Z6EY84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1553431:MCB1EB RS04490
gene id: 1553431:MCB1EB_RS04490
uniprot id: A0A2Z6EUA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1553431:MCB1EB RS04460
gene id: 1553431:MCB1EB_RS04460
uniprot id: A0A2Z6EUA3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1553431:MCB1EB RS00450
gene id: 1553431:MCB1EB_RS00450
uniprot id: A0A2Z6ES67
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS05915
gene id: 1553431:MCB1EB_RS05915
uniprot id: A0A2Z6EW46
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1553431:MCB1EB RS10385
gene id: 1553431:MCB1EB_RS10385
uniprot id: A0A2Z6EXJ7
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1553431:MCB1EB RS09965
gene id: 1553431:MCB1EB_RS09965
uniprot id: A0A2Z6EXC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1553431:MCB1EB RS10420
gene id: 1553431:MCB1EB_RS10420
uniprot id: A0A2Z6EXM8
names: Similarity
messages: Belongs to the UPF0235 family.

1553431:MCB1EB RS01245
gene id: 1553431:MCB1EB_RS01245
uniprot id: A0A2Z6ESP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1553431:MCB1EB RS01845
gene id: 1553431:MCB1EB_RS01845
uniprot id: A0A2Z6ESZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS10860
gene id: 1553431:MCB1EB_RS10860
uniprot id: A0A2Z6EXU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1553431:MCB1EB RS03790
gene id: 1553431:MCB1EB_RS03790
uniprot id: A0A2Z6ETZ9
names: Similarity
messages: Belongs to the YfgM family.

1553431:MCB1EB RS04405
gene id: 1553431:MCB1EB_RS04405
uniprot id: A0A2Z6EUC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1553431:MCB1EB RS01575
gene id: 1553431:MCB1EB_RS01575
uniprot id: A0A2Z6EST2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1553431:MCB1EB RS01305
gene id: 1553431:MCB1EB_RS01305
uniprot id: A0A2Z6ESN7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1553431:MCB1EB RS00180
gene id: 1553431:MCB1EB_RS00180
uniprot id: A0A2Z6ES16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1553431:MCB1EB RS00505
gene id: 1553431:MCB1EB_RS00505
uniprot id: A0A2Z6ES71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1553431:MCB1EB RS05360
gene id: 1553431:MCB1EB_RS05360
uniprot id: A0A2Z6EUQ6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1553431:MCB1EB RS08910
gene id: 1553431:MCB1EB_RS08910
uniprot id: A0A2Z6EWT2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS01440
gene id: 1553431:MCB1EB_RS01440
uniprot id: A0A2Z6ESP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1553431:MCB1EB RS01255
gene id: 1553431:MCB1EB_RS01255
uniprot id: A0A2Z6ESM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1553431:MCB1EB RS01340
gene id: 1553431:MCB1EB_RS01340
uniprot id: A0A2Z6ESP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1553431:MCB1EB RS10500
gene id: 1553431:MCB1EB_RS10500
uniprot id: A0A2Z6EXT8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1553431:MCB1EB RS11630
gene id: 1553431:MCB1EB_RS11630
uniprot id: A0A2Z6EYA7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1553431:MCB1EB RS07215
gene id: 1553431:MCB1EB_RS07215
uniprot id: A0A2Z6EVX3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1553431:MCB1EB RS09895
gene id: 1553431:MCB1EB_RS09895
uniprot id: A0A2Z6EY93
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1553431:MCB1EB RS11460
gene id: 1553431:MCB1EB_RS11460
uniprot id: A0A2Z6EY90
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS08275
gene id: 1553431:MCB1EB_RS08275
uniprot id: A0A2Z6EWE0
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1553431:MCB1EB RS11625
gene id: 1553431:MCB1EB_RS11625
uniprot id: A0A2Z6EYB7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1553431:MCB1EB RS07160
gene id: 1553431:MCB1EB_RS07160
uniprot id: A0A2Z6EVW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1553431:MCB1EB RS05720
gene id: 1553431:MCB1EB_RS05720
uniprot id: A0A2Z6EUX4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1553431:MCB1EB RS10080
gene id: 1553431:MCB1EB_RS10080
uniprot id: A0A2Z6EXE3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1553431:MCB1EB RS09935
gene id: 1553431:MCB1EB_RS09935
uniprot id: A0A2Z6EXB4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1553431:MCB1EB RS00725
gene id: 1553431:MCB1EB_RS00725
uniprot id: A0A2Z6ESC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1553431:MCB1EB RS11615
gene id: 1553431:MCB1EB_RS11615
uniprot id: A0A2Z6EYG7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1553431:MCB1EB RS01865
gene id: 1553431:MCB1EB_RS01865
uniprot id: A0A2Z6ESZ1
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1553431:MCB1EB RS09780
gene id: 1553431:MCB1EB_RS09780
uniprot id: A0A2Z6EXE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1553431:MCB1EB RS09755
gene id: 1553431:MCB1EB_RS09755
uniprot id: A0A2Z6EXC0
names: Function
names: Similarity
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Might have a role in establishing the nucleoid structure of elementary bodies.

1553431:MCB1EB RS02935
gene id: 1553431:MCB1EB_RS02935
uniprot id: A0A2Z6ETI0
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1553431:MCB1EB RS00525
gene id: 1553431:MCB1EB_RS00525
uniprot id: A0A2Z6ES86
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1553431:MCB1EB RS04950
gene id: 1553431:MCB1EB_RS04950
uniprot id: A0A2Z6EUI0
names: Similarity
messages: Belongs to the universal stress protein A family.

1553431:MCB1EB RS04685
gene id: 1553431:MCB1EB_RS04685
uniprot id: A0A2Z6EUD8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1553431:MCB1EB RS09860
gene id: 1553431:MCB1EB_RS09860
uniprot id: A0A2Z6EXJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS01230
gene id: 1553431:MCB1EB_RS01230
uniprot id: A0A2Z6ESL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1553431:MCB1EB RS09870
gene id: 1553431:MCB1EB_RS09870
uniprot id: A0A2Z6EX98
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1553431:MCB1EB RS07155
gene id: 1553431:MCB1EB_RS07155
uniprot id: A0A2Z6EVV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1553431:MCB1EB RS00255
gene id: 1553431:MCB1EB_RS00255
uniprot id: A0A2Z6ES39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS11105
gene id: 1553431:MCB1EB_RS11105
uniprot id: A0A2Z6EY10
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1553431:MCB1EB RS11585
gene id: 1553431:MCB1EB_RS11585
uniprot id: A0A2Z6EYF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1553431:MCB1EB RS09630
gene id: 1553431:MCB1EB_RS09630
uniprot id: A0A2Z6EXB0
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1553431:MCB1EB RS04370
gene id: 1553431:MCB1EB_RS04370
uniprot id: A0A2Z6EU84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1553431:MCB1EB RS08900
gene id: 1553431:MCB1EB_RS08900
uniprot id: A0A2Z6EWS8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1553431:MCB1EB RS09490
gene id: 1553431:MCB1EB_RS09490
uniprot id: A0A2Z6EY18
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS09945
gene id: 1553431:MCB1EB_RS09945
uniprot id: A0A2Z6EYA3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1553431:MCB1EB RS04675
gene id: 1553431:MCB1EB_RS04675
uniprot id: A0A2Z6EUC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1553431:MCB1EB RS00760
gene id: 1553431:MCB1EB_RS00760
uniprot id: A0A2Z6ESC8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1553431:MCB1EB RS11230
gene id: 1553431:MCB1EB_RS11230
uniprot id: A0A2Z6EY44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1553431:MCB1EB RS00170
gene id: 1553431:MCB1EB_RS00170
uniprot id: A0A2Z6ES20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1553431:MCB1EB RS05200
gene id: 1553431:MCB1EB_RS05200
uniprot id: A0A2Z6EUN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1553431:MCB1EB RS03480
gene id: 1553431:MCB1EB_RS03480
uniprot id: A0A2Z6ETU6
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS04580
gene id: 1553431:MCB1EB_RS04580
uniprot id: A0A2Z6EUB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1553431:MCB1EB RS00010
gene id: 1553431:MCB1EB_RS00010
uniprot id: A0A2Z6ERX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1553431:MCB1EB RS10515
gene id: 1553431:MCB1EB_RS10515
uniprot id: A0A2Z6EXP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1553431:MCB1EB RS09385
gene id: 1553431:MCB1EB_RS09385
uniprot id: A0A2Z6EY00
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1553431:MCB1EB RS04040
gene id: 1553431:MCB1EB_RS04040
uniprot id: A0A2Z6EU54
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1553431:MCB1EB RS03085
gene id: 1553431:MCB1EB_RS03085
uniprot id: A0A2Z6ETQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS00355
gene id: 1553431:MCB1EB_RS00355
uniprot id: A0A2Z6ES63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1553431:MCB1EB RS00375
gene id: 1553431:MCB1EB_RS00375
uniprot id: A0A2Z6ES52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS06950
gene id: 1553431:MCB1EB_RS06950
uniprot id: A0A2Z6EVP1
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1553431:MCB1EB RS10655
gene id: 1553431:MCB1EB_RS10655
uniprot id: A0A2Z6EXQ0
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

1553431:MCB1EB RS09890
gene id: 1553431:MCB1EB_RS09890
uniprot id: A0A2Z6EX95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1553431:MCB1EB RS00220
gene id: 1553431:MCB1EB_RS00220
uniprot id: A0A2Z6ES31
names: Similarity
messages: Belongs to the leucine-binding protein family.

1553431:MCB1EB RS10485
gene id: 1553431:MCB1EB_RS10485
uniprot id: A0A2Z6EXM0
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1553431:MCB1EB RS05860
gene id: 1553431:MCB1EB_RS05860
uniprot id: A0A2Z6EV03
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1553431:MCB1EB RS03180
gene id: 1553431:MCB1EB_RS03180
uniprot id: A0A2Z6ETN9
names: Similarity
messages: Belongs to the peptidase M24B family.

1553431:MCB1EB RS04375
gene id: 1553431:MCB1EB_RS04375
uniprot id: A0A2Z6EU97
names: Similarity
messages: Belongs to the asparaginase 1 family.

1553431:MCB1EB RS00885
gene id: 1553431:MCB1EB_RS00885
uniprot id: A0A2Z6ESF9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1553431:MCB1EB RS10220
gene id: 1553431:MCB1EB_RS10220
uniprot id: A0A2Z6EXJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1553431:MCB1EB RS10890
gene id: 1553431:MCB1EB_RS10890
uniprot id: A0A2Z6EXV7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS10585
gene id: 1553431:MCB1EB_RS10585
uniprot id: A0A2Z6EXR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1553431:MCB1EB RS10745
gene id: 1553431:MCB1EB_RS10745
uniprot id: A0A2Z6EXS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1553431:MCB1EB RS04300
gene id: 1553431:MCB1EB_RS04300
uniprot id: A0A2Z6EUA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1553431:MCB1EB RS06485
gene id: 1553431:MCB1EB_RS06485
uniprot id: A0A2Z6EVF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1553431:MCB1EB RS03485
gene id: 1553431:MCB1EB_RS03485
uniprot id: A0A2Z6ETT2
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1553431:MCB1EB RS10665
gene id: 1553431:MCB1EB_RS10665
uniprot id: A0A2Z6EYI6
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS02570
gene id: 1553431:MCB1EB_RS02570
uniprot id: A0A2Z6ETB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1553431:MCB1EB RS04615
gene id: 1553431:MCB1EB_RS04615
uniprot id: A0A2Z6EUC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1553431:MCB1EB RS03035
gene id: 1553431:MCB1EB_RS03035
uniprot id: A0A2Z6ETP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctF family.
messages: Cell surface
messages: Secreted

1553431:MCB1EB RS03755
gene id: 1553431:MCB1EB_RS03755
uniprot id: A0A2Z6ETX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1553431:MCB1EB RS06035
gene id: 1553431:MCB1EB_RS06035
uniprot id: A0A2Z6EV48
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1553431:MCB1EB RS04235
gene id: 1553431:MCB1EB_RS04235
uniprot id: A0A2Z6EU60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1553431:MCB1EB RS03300
gene id: 1553431:MCB1EB_RS03300
uniprot id: A0A2Z6ETS2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1553431:MCB1EB RS08795
gene id: 1553431:MCB1EB_RS08795
uniprot id: A0A2Z6EWQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1553431:MCB1EB RS03960
gene id: 1553431:MCB1EB_RS03960
uniprot id: A0A2Z6EU27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1553431:MCB1EB RS00360
gene id: 1553431:MCB1EB_RS00360
uniprot id: A0A2Z6ES59
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS05870
gene id: 1553431:MCB1EB_RS05870
uniprot id: A0A2Z6EW39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1553431:MCB1EB RS02470
gene id: 1553431:MCB1EB_RS02470
uniprot id: A0A2Z6ETD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1553431:MCB1EB RS09810
gene id: 1553431:MCB1EB_RS09810
uniprot id: A0A2Z6EXI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1553431:MCB1EB RS04130
gene id: 1553431:MCB1EB_RS04130
uniprot id: A0A2Z6EU37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1553431:MCB1EB RS08980
gene id: 1553431:MCB1EB_RS08980
uniprot id: A0A2Z6EWR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1553431:MCB1EB RS09000
gene id: 1553431:MCB1EB_RS09000
uniprot id: A0A2Z6EX35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1553431:MCB1EB RS02680
gene id: 1553431:MCB1EB_RS02680
uniprot id: A0A2Z6ETD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1553431:MCB1EB RS00015
gene id: 1553431:MCB1EB_RS00015
uniprot id: A0A2Z6ERY5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1553431:MCB1EB RS08545
gene id: 1553431:MCB1EB_RS08545
uniprot id: A0A2Z6EWK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1553431:MCB1EB RS00895
gene id: 1553431:MCB1EB_RS00895
uniprot id: A0A2Z6ESE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1553431:MCB1EB RS04910
gene id: 1553431:MCB1EB_RS04910
uniprot id: A0A2Z6EUK7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1553431:MCB1EB RS10570
gene id: 1553431:MCB1EB_RS10570
uniprot id: A0A2Z6EXY5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1553431:MCB1EB RS04990
gene id: 1553431:MCB1EB_RS04990
uniprot id: A0A2Z6EUN0
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1553431:MCB1EB RS08520
gene id: 1553431:MCB1EB_RS08520
uniprot id: A0A2Z6EWH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1553431:MCB1EB RS04965
gene id: 1553431:MCB1EB_RS04965
uniprot id: A0A2Z6EUN5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1553431:MCB1EB RS11575
gene id: 1553431:MCB1EB_RS11575
uniprot id: A0A2Z6EYA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

1553431:MCB1EB RS05090
gene id: 1553431:MCB1EB_RS05090
uniprot id: A0A2Z6EUQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1553431:MCB1EB RS06355
gene id: 1553431:MCB1EB_RS06355
uniprot id: A0A2Z6EVA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1553431:MCB1EB RS01080
gene id: 1553431:MCB1EB_RS01080
uniprot id: A0A2Z6ESJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1553431:MCB1EB RS00785
gene id: 1553431:MCB1EB_RS00785
uniprot id: A0A2Z6ESE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS06965
gene id: 1553431:MCB1EB_RS06965
uniprot id: A0A2Z6EVU5
names: Similarity
messages: Belongs to the bacterial secretin family.

1553431:MCB1EB RS06875
gene id: 1553431:MCB1EB_RS06875
uniprot id: A0A2Z6EVQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1553431:MCB1EB RS00750
gene id: 1553431:MCB1EB_RS00750
uniprot id: A0A2Z6ESC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1553431:MCB1EB RS12195
gene id: 1553431:MCB1EB_RS12195
uniprot id: A0A2Z6EVB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1553431:MCB1EB RS01375
gene id: 1553431:MCB1EB_RS01375
uniprot id: A0A2Z6ESN4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1553431:MCB1EB RS01420
gene id: 1553431:MCB1EB_RS01420
uniprot id: A0A2Z6ESQ6
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1553431:MCB1EB RS07780
gene id: 1553431:MCB1EB_RS07780
uniprot id: A0A2Z6EWB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1553431:MCB1EB RS10250
gene id: 1553431:MCB1EB_RS10250
uniprot id: A0A2Z6EXN8
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

1553431:MCB1EB RS00575
gene id: 1553431:MCB1EB_RS00575
uniprot id: A0A2Z6ESA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1553431:MCB1EB RS01175
gene id: 1553431:MCB1EB_RS01175
uniprot id: A0A2Z6ESJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1553431:MCB1EB RS09880
gene id: 1553431:MCB1EB_RS09880
uniprot id: A0A2Z6EXH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gmhB family.
messages: Cytoplasm
messages: Monomer.

1553431:MCB1EB RS03545
gene id: 1553431:MCB1EB_RS03545
uniprot id: A0A2Z6ETX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS11355
gene id: 1553431:MCB1EB_RS11355
uniprot id: A0A2Z6EY60
names: Subcellular Location Annotation
messages: Secreted

1553431:MCB1EB RS01090
gene id: 1553431:MCB1EB_RS01090
uniprot id: A0A2Z6ESK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1553431:MCB1EB RS02625
gene id: 1553431:MCB1EB_RS02625
uniprot id: A0A2Z6ETG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1553431:MCB1EB RS11790
gene id: 1553431:MCB1EB_RS11790
uniprot id: A0A2Z6EYB5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS03785
gene id: 1553431:MCB1EB_RS03785
uniprot id: A0A2Z6EUY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS10285
gene id: 1553431:MCB1EB_RS10285
uniprot id: A0A2Z6EXH7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1553431:MCB1EB RS10900
gene id: 1553431:MCB1EB_RS10900
uniprot id: A0A2Z6EXX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS10380
gene id: 1553431:MCB1EB_RS10380
uniprot id: A0A2Z6EXU3
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS03800
gene id: 1553431:MCB1EB_RS03800
uniprot id: A0A2Z6EU09
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1553431:MCB1EB RS04410
gene id: 1553431:MCB1EB_RS04410
uniprot id: A0A2Z6EU96
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS05920
gene id: 1553431:MCB1EB_RS05920
uniprot id: A0A2Z6EV99
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1553431:MCB1EB RS08390
gene id: 1553431:MCB1EB_RS08390
uniprot id: A0A2Z6EWG9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1553431:MCB1EB RS05640
gene id: 1553431:MCB1EB_RS05640
uniprot id: A0A2Z6EUW5
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1553431:MCB1EB RS01915
gene id: 1553431:MCB1EB_RS01915
uniprot id: A0A2Z6ET02
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1553431:MCB1EB RS03765
gene id: 1553431:MCB1EB_RS03765
uniprot id: A0A2Z6EU13
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1553431:MCB1EB RS02615
gene id: 1553431:MCB1EB_RS02615
uniprot id: A0A2Z6ETC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1553431:MCB1EB RS01000
gene id: 1553431:MCB1EB_RS01000
uniprot id: A0A2Z6ESG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS08760
gene id: 1553431:MCB1EB_RS08760
uniprot id: A0A2Z6EWV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1553431:MCB1EB RS09970
gene id: 1553431:MCB1EB_RS09970
uniprot id: A0A2Z6EXB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1553431:MCB1EB RS03990
gene id: 1553431:MCB1EB_RS03990
uniprot id: A0A2Z6EU44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. T3SS SctC subfamily.
messages: Cell outer membrane
messages: Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
messages: The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex.

1553431:MCB1EB RS03310
gene id: 1553431:MCB1EB_RS03310
uniprot id: A0A2Z6ETP2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1553431:MCB1EB RS10075
gene id: 1553431:MCB1EB_RS10075
uniprot id: A0A2Z6EXN1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1553431:MCB1EB RS11235
gene id: 1553431:MCB1EB_RS11235
uniprot id: A0A2Z6EY66
names: Subcellular Location Annotation
messages: Cytoplasm

1553431:MCB1EB RS02665
gene id: 1553431:MCB1EB_RS02665
uniprot id: A0A2Z6ETD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1553431:MCB1EB RS04665
gene id: 1553431:MCB1EB_RS04665
uniprot id: A0A2Z6EUD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1553431:MCB1EB RS02500
gene id: 1553431:MCB1EB_RS02500
uniprot id: A0A2Z6ETE7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1553431:MCB1EB RS05130
gene id: 1553431:MCB1EB_RS05130
uniprot id: A0A2Z6EVM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1553431:MCB1EB RS00570
gene id: 1553431:MCB1EB_RS00570
uniprot id: A0A2Z6ES96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1553431:MCB1EB RS04820
gene id: 1553431:MCB1EB_RS04820
uniprot id: A0A2Z6EVH7
names: Similarity
messages: Belongs to the GARS family.

1553431:MCB1EB RS09275
gene id: 1553431:MCB1EB_RS09275
uniprot id: A0A2Z6EWY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1553431:MCB1EB RS09730
gene id: 1553431:MCB1EB_RS09730
uniprot id: A0A2Z6EXE0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1553431:MCB1EB RS01910
gene id: 1553431:MCB1EB_RS01910
uniprot id: A0A2Z6ET20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS08885
gene id: 1553431:MCB1EB_RS08885
uniprot id: A0A2Z6EWV2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1553431:MCB1EB RS04805
gene id: 1553431:MCB1EB_RS04805
uniprot id: A0A2Z6EUI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1553431:MCB1EB RS11045
gene id: 1553431:MCB1EB_RS11045
uniprot id: A0A2Z6EXZ4
names: Similarity
messages: Belongs to the UPF0234 family.

1553431:MCB1EB RS10450
gene id: 1553431:MCB1EB_RS10450
uniprot id: A0A2Z6EXS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1553431:MCB1EB RS04145
gene id: 1553431:MCB1EB_RS04145
uniprot id: A0A2Z6EU43
names: Similarity
messages: Belongs to the peptidase M1 family.

1553431:MCB1EB RS01140
gene id: 1553431:MCB1EB_RS01140
uniprot id: A0A2Z6ESK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1553431:MCB1EB RS10925
gene id: 1553431:MCB1EB_RS10925
uniprot id: A0A2Z6EXX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1553431:MCB1EB RS01085
gene id: 1553431:MCB1EB_RS01085
uniprot id: A0A2Z6ESK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1553431:MCB1EB RS01315
gene id: 1553431:MCB1EB_RS01315
uniprot id: A0A2Z6ESN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1553431:MCB1EB RS03150
gene id: 1553431:MCB1EB_RS03150
uniprot id: A0A2Z6ETP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. T3SS SctC subfamily.
messages: Cell outer membrane
messages: Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
messages: The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex.

1553431:MCB1EB RS09005
gene id: 1553431:MCB1EB_RS09005
uniprot id: A0A2Z6EWU7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1553431:MCB1EB RS01905
gene id: 1553431:MCB1EB_RS01905
uniprot id: A0A2Z6ET18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS05545
gene id: 1553431:MCB1EB_RS05545
uniprot id: A0A2Z6EV06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1553431:MCB1EB RS00070
gene id: 1553431:MCB1EB_RS00070
uniprot id: A0A2Z6ES02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1553431:MCB1EB RS03380
gene id: 1553431:MCB1EB_RS03380
uniprot id: A0A2Z6ETR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1553431:MCB1EB RS03305
gene id: 1553431:MCB1EB_RS03305
uniprot id: A0A2Z6ETU0
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS00350
gene id: 1553431:MCB1EB_RS00350
uniprot id: A0A2Z6ES47
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1553431:MCB1EB RS03370
gene id: 1553431:MCB1EB_RS03370
uniprot id: A0A2Z6EUR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1553431:MCB1EB RS06510
gene id: 1553431:MCB1EB_RS06510
uniprot id: A0A2Z6EVE0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS08750
gene id: 1553431:MCB1EB_RS08750
uniprot id: A0A2Z6EWP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1553431:MCB1EB RS07175
gene id: 1553431:MCB1EB_RS07175
uniprot id: A0A2Z6EWT4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1553431:MCB1EB RS06525
gene id: 1553431:MCB1EB_RS06525
uniprot id: A0A2Z6EVJ2
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS00550
gene id: 1553431:MCB1EB_RS00550
uniprot id: A0A2Z6ES98
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1553431:MCB1EB RS10610
gene id: 1553431:MCB1EB_RS10610
uniprot id: A0A2Z6EXR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1553431:MCB1EB RS03535
gene id: 1553431:MCB1EB_RS03535
uniprot id: A0A2Z6ETW0
names: Caution
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1553431:MCB1EB RS04500
gene id: 1553431:MCB1EB_RS04500
uniprot id: A0A2Z6EVC8
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1553431:MCB1EB RS11735
gene id: 1553431:MCB1EB_RS11735
uniprot id: A0A2Z6EYA6
names: Similarity
messages: Belongs to the UPF0250 family.

1553431:MCB1EB RS10155
gene id: 1553431:MCB1EB_RS10155
uniprot id: A0A2Z6EXF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1553431:MCB1EB RS10600
gene id: 1553431:MCB1EB_RS10600
uniprot id: A0A2Z6EXQ2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS04700
gene id: 1553431:MCB1EB_RS04700
uniprot id: A0A2Z6EUC9
names: Subcellular Location Annotation
messages: Cytoplasm

1553431:MCB1EB RS08630
gene id: 1553431:MCB1EB_RS08630
uniprot id: A0A2Z6EWL2
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1553431:MCB1EB RS04255
gene id: 1553431:MCB1EB_RS04255
uniprot id: A0A2Z6EU61
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1553431:MCB1EB RS03450
gene id: 1553431:MCB1EB_RS03450
uniprot id: A0A2Z6ETU8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1553431:MCB1EB RS04885
gene id: 1553431:MCB1EB_RS04885
uniprot id: A0A2Z6EUP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS10815
gene id: 1553431:MCB1EB_RS10815
uniprot id: A0A2Z6EXU1
names: Similarity
messages: Belongs to the peptidase M16 family.

1553431:MCB1EB RS10195
gene id: 1553431:MCB1EB_RS10195
uniprot id: A0A2Z6EXI4
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1553431:MCB1EB RS01215
gene id: 1553431:MCB1EB_RS01215
uniprot id: A0A2Z6ESL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1553431:MCB1EB RS09170
gene id: 1553431:MCB1EB_RS09170
uniprot id: A0A2Z6EX29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1553431:MCB1EB RS01325
gene id: 1553431:MCB1EB_RS01325
uniprot id: A0A2Z6ESN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1553431:MCB1EB RS00770
gene id: 1553431:MCB1EB_RS00770
uniprot id: A0A2Z6ESE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1553431:MCB1EB RS11595
gene id: 1553431:MCB1EB_RS11595
uniprot id: A0A2Z6EY76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1553431:MCB1EB RS11090
gene id: 1553431:MCB1EB_RS11090
uniprot id: A0A2Z6EY80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1553431:MCB1EB RS05645
gene id: 1553431:MCB1EB_RS05645
uniprot id: A0A2Z6EV25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1553431:MCB1EB RS01205
gene id: 1553431:MCB1EB_RS01205
uniprot id: A0A2Z6ESM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1553431:MCB1EB RS00445
gene id: 1553431:MCB1EB_RS00445
uniprot id: A0A2Z6ES65
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS09815
gene id: 1553431:MCB1EB_RS09815
uniprot id: A0A2Z6EX97
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1553431:MCB1EB RS03805
gene id: 1553431:MCB1EB_RS03805
uniprot id: A0A2Z6ETY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1553431:MCB1EB RS06860
gene id: 1553431:MCB1EB_RS06860
uniprot id: A0A2Z6EVP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1553431:MCB1EB RS09290
gene id: 1553431:MCB1EB_RS09290
uniprot id: A0A2Z6EWZ0
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

1553431:MCB1EB RS10215
gene id: 1553431:MCB1EB_RS10215
uniprot id: A0A2Z6EYF0
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1553431:MCB1EB RS05555
gene id: 1553431:MCB1EB_RS05555
uniprot id: A0A2Z6EUW3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1553431:MCB1EB RS05350
gene id: 1553431:MCB1EB_RS05350
uniprot id: A0A2Z6EUW0
names: Similarity
messages: Belongs to the ArsC family.

1553431:MCB1EB RS06380
gene id: 1553431:MCB1EB_RS06380
uniprot id: A0A2Z6EWE5
names: Similarity
messages: Belongs to the glutamine synthetase family.

1553431:MCB1EB RS05685
gene id: 1553431:MCB1EB_RS05685
uniprot id: A0A2Z6EV45
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1553431:MCB1EB RS00205
gene id: 1553431:MCB1EB_RS00205
uniprot id: A0A2Z6ES26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1553431:MCB1EB RS01365
gene id: 1553431:MCB1EB_RS01365
uniprot id: A0A2Z6ESP7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1553431:MCB1EB RS08730
gene id: 1553431:MCB1EB_RS08730
uniprot id: A0A2Z6EWS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1553431:MCB1EB RS09505
gene id: 1553431:MCB1EB_RS09505
uniprot id: A0A2Z6EXD1
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1553431:MCB1EB RS10875
gene id: 1553431:MCB1EB_RS10875
uniprot id: A0A2Z6EXW7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1553431:MCB1EB RS09955
gene id: 1553431:MCB1EB_RS09955
uniprot id: A0A2Z6EXG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS02365
gene id: 1553431:MCB1EB_RS02365
uniprot id: A0A2Z6ETA4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1553431:MCB1EB RS02795
gene id: 1553431:MCB1EB_RS02795
uniprot id: A0A2Z6ETK2
names: Similarity
messages: Belongs to the UPF0423 family.

1553431:MCB1EB RS00260
gene id: 1553431:MCB1EB_RS00260
uniprot id: A0A2Z6ES34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1553431:MCB1EB RS03285
gene id: 1553431:MCB1EB_RS03285
uniprot id: A0A2Z6ETT6
names: Similarity
messages: Belongs to the fabD family.

1553431:MCB1EB RS01515
gene id: 1553431:MCB1EB_RS01515
uniprot id: A0A2Z6ESS9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1553431:MCB1EB RS08790
gene id: 1553431:MCB1EB_RS08790
uniprot id: A0A2Z6EWW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1553431:MCB1EB RS10135
gene id: 1553431:MCB1EB_RS10135
uniprot id: A0A2Z6EXE6
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1553431:MCB1EB RS11030
gene id: 1553431:MCB1EB_RS11030
uniprot id: A0A2Z6EY24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1553431:MCB1EB RS11020
gene id: 1553431:MCB1EB_RS11020
uniprot id: A0A2Z6EYM5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1553431:MCB1EB RS11730
gene id: 1553431:MCB1EB_RS11730
uniprot id: A0A2Z6EYB0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1553431:MCB1EB RS11010
gene id: 1553431:MCB1EB_RS11010
uniprot id: A0A2Z6EXX1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1553431:MCB1EB RS09010
gene id: 1553431:MCB1EB_RS09010
uniprot id: A0A2Z6EWU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1553431:MCB1EB RS08770
gene id: 1553431:MCB1EB_RS08770
uniprot id: A0A2Z6EWM5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1553431:MCB1EB RS10440
gene id: 1553431:MCB1EB_RS10440
uniprot id: A0A2Z6EXL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1553431:MCB1EB RS02520
gene id: 1553431:MCB1EB_RS02520
uniprot id: A0A2Z6ETD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1553431:MCB1EB RS07075
gene id: 1553431:MCB1EB_RS07075
uniprot id: A0A2Z6EVR0
names: Similarity
messages: Belongs to the peptidase S66 family.

1553431:MCB1EB RS10630
gene id: 1553431:MCB1EB_RS10630
uniprot id: A0A2Z6EXQ4
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1553431:MCB1EB RS04815
gene id: 1553431:MCB1EB_RS04815
uniprot id: A0A2Z6EUI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1553431:MCB1EB RS02785
gene id: 1553431:MCB1EB_RS02785
uniprot id: A0A2Z6ETH5
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS04825
gene id: 1553431:MCB1EB_RS04825
uniprot id: A0A2Z6EUN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1553431:MCB1EB RS05840
gene id: 1553431:MCB1EB_RS05840
uniprot id: A0A2Z6EV11
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

1553431:MCB1EB RS04430
gene id: 1553431:MCB1EB_RS04430
uniprot id: A0A2Z6EUD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1553431:MCB1EB RS11165
gene id: 1553431:MCB1EB_RS11165
uniprot id: A0A2Z6EY04
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1553431:MCB1EB RS08765
gene id: 1553431:MCB1EB_RS08765
uniprot id: A0A2Z6EWP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1553431:MCB1EB RS02425
gene id: 1553431:MCB1EB_RS02425
uniprot id: A0A2Z6ET83
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS01895
gene id: 1553431:MCB1EB_RS01895
uniprot id: A0A2Z6ET24
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1553431:MCB1EB RS00080
gene id: 1553431:MCB1EB_RS00080
uniprot id: A0A2Z6ERZ8
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1553431:MCB1EB RS01780
gene id: 1553431:MCB1EB_RS01780
uniprot id: A0A2Z6ESW8
names: Similarity
messages: Belongs to the TrpC family.

1553431:MCB1EB RS08935
gene id: 1553431:MCB1EB_RS08935
uniprot id: A0A2Z6EXR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctL stator family.
messages: Cytoplasm

1553431:MCB1EB RS02505
gene id: 1553431:MCB1EB_RS02505
uniprot id: A0A2Z6ETB0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1553431:MCB1EB RS05655
gene id: 1553431:MCB1EB_RS05655
uniprot id: A0A2Z6EUY3
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1553431:MCB1EB RS03945
gene id: 1553431:MCB1EB_RS03945
uniprot id: A0A2Z6EU14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

1553431:MCB1EB RS00890
gene id: 1553431:MCB1EB_RS00890
uniprot id: A0A2Z6ESG6
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS02335
gene id: 1553431:MCB1EB_RS02335
uniprot id: A0A2Z6ET88
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1553431:MCB1EB RS11245
gene id: 1553431:MCB1EB_RS11245
uniprot id: A0A2Z6EY26
names: Similarity
messages: Belongs to the P(II) protein family.

1553431:MCB1EB RS01225
gene id: 1553431:MCB1EB_RS01225
uniprot id: A0A2Z6ESK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1553431:MCB1EB RS10995
gene id: 1553431:MCB1EB_RS10995
uniprot id: A0A2Z6EXY4
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1553431:MCB1EB RS04280
gene id: 1553431:MCB1EB_RS04280
uniprot id: A0A2Z6EUA2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1553431:MCB1EB RS01200
gene id: 1553431:MCB1EB_RS01200
uniprot id: A0A2Z6ESL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1553431:MCB1EB RS01100
gene id: 1553431:MCB1EB_RS01100
uniprot id: A0A2Z6ESJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1553431:MCB1EB RS06325
gene id: 1553431:MCB1EB_RS06325
uniprot id: A0A2Z6EVB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1553431:MCB1EB RS03515
gene id: 1553431:MCB1EB_RS03515
uniprot id: A0A2Z6ETX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1553431:MCB1EB RS10145
gene id: 1553431:MCB1EB_RS10145
uniprot id: A0A2Z6EXH2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1553431:MCB1EB RS01540
gene id: 1553431:MCB1EB_RS01540
uniprot id: A0A2Z6ESS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1553431:MCB1EB RS01360
gene id: 1553431:MCB1EB_RS01360
uniprot id: A0A2Z6ESP8
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS10965
gene id: 1553431:MCB1EB_RS10965
uniprot id: A0A2Z6EXW9
names: Subcellular Location Annotation
messages: Cytoplasm

1553431:MCB1EB RS07235
gene id: 1553431:MCB1EB_RS07235
uniprot id: A0A2Z6EVZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1553431:MCB1EB RS02890
gene id: 1553431:MCB1EB_RS02890
uniprot id: A0A2Z6ETJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1553431:MCB1EB RS10400
gene id: 1553431:MCB1EB_RS10400
uniprot id: A0A2Z6EXR9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS08605
gene id: 1553431:MCB1EB_RS08605
uniprot id: A0A2Z6EWM9
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS06170
gene id: 1553431:MCB1EB_RS06170
uniprot id: A0A2Z6EV87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1553431:MCB1EB RS06185
gene id: 1553431:MCB1EB_RS06185
uniprot id: A0A2Z6EV81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1553431:MCB1EB RS03290
gene id: 1553431:MCB1EB_RS03290
uniprot id: A0A2Z6ETP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1553431:MCB1EB RS00880
gene id: 1553431:MCB1EB_RS00880
uniprot id: A0A2Z6ESF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1553431:MCB1EB RS02550
gene id: 1553431:MCB1EB_RS02550
uniprot id: A0A2Z6ETC2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1553431:MCB1EB RS01160
gene id: 1553431:MCB1EB_RS01160
uniprot id: A0A2Z6ESL1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1553431:MCB1EB RS02300
gene id: 1553431:MCB1EB_RS02300
uniprot id: A0A2Z6ET90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

1553431:MCB1EB RS11610
gene id: 1553431:MCB1EB_RS11610
uniprot id: A0A2Z6EYD4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1553431:MCB1EB RS11465
gene id: 1553431:MCB1EB_RS11465
uniprot id: A0A2Z6EY79
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1553431:MCB1EB RS09560
gene id: 1553431:MCB1EB_RS09560
uniprot id: A0A2Z6EX49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1553431:MCB1EB RS10695
gene id: 1553431:MCB1EB_RS10695
uniprot id: A0A2Z6EXR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1553431:MCB1EB RS10115
gene id: 1553431:MCB1EB_RS10115
uniprot id: A0A2Z6EYD5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1553431:MCB1EB RS05325
gene id: 1553431:MCB1EB_RS05325
uniprot id: A0A2Z6EUX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1553431:MCB1EB RS09195
gene id: 1553431:MCB1EB_RS09195
uniprot id: A0A2Z6EWX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1553431:MCB1EB RS03055
gene id: 1553431:MCB1EB_RS03055
uniprot id: A0A2Z6ETP4
names: Similarity
messages: Belongs to the LcrH/SycD chaperone family.

1553431:MCB1EB RS00190
gene id: 1553431:MCB1EB_RS00190
uniprot id: A0A2Z6ES14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1553431:MCB1EB RS05805
gene id: 1553431:MCB1EB_RS05805
uniprot id: A0A2Z6EV50
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1553431:MCB1EB RS06955
gene id: 1553431:MCB1EB_RS06955
uniprot id: A0A2Z6EVN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1553431:MCB1EB RS10455
gene id: 1553431:MCB1EB_RS10455
uniprot id: A0A2Z6EXL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS00175
gene id: 1553431:MCB1EB_RS00175
uniprot id: A0A2Z6ES18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1553431:MCB1EB RS05900
gene id: 1553431:MCB1EB_RS05900
uniprot id: A0A2Z6EV79
names: Subcellular Location Annotation
messages: Cell outer membrane

1553431:MCB1EB RS03980
gene id: 1553431:MCB1EB_RS03980
uniprot id: A0A2Z6EU06
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1553431:MCB1EB RS03590
gene id: 1553431:MCB1EB_RS03590
uniprot id: A0A2Z6ETW7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS03270
gene id: 1553431:MCB1EB_RS03270
uniprot id: A0A2Z6EUM9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1553431:MCB1EB RS01280
gene id: 1553431:MCB1EB_RS01280
uniprot id: A0A2Z6ESM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1553431:MCB1EB RS09820
gene id: 1553431:MCB1EB_RS09820
uniprot id: A0A2Z6EX88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1553431:MCB1EB RS10790
gene id: 1553431:MCB1EB_RS10790
uniprot id: A0A2Z6EXT6
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS05220
gene id: 1553431:MCB1EB_RS05220
uniprot id: A0A2Z6EUP7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1553431:MCB1EB RS00335
gene id: 1553431:MCB1EB_RS00335
uniprot id: A0A2Z6ES50
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS04380
gene id: 1553431:MCB1EB_RS04380
uniprot id: A0A2Z6EUC4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1553431:MCB1EB RS01570
gene id: 1553431:MCB1EB_RS01570
uniprot id: A0A2Z6EST6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1553431:MCB1EB RS03090
gene id: 1553431:MCB1EB_RS03090
uniprot id: A0A2Z6ETK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1553431:MCB1EB RS02775
gene id: 1553431:MCB1EB_RS02775
uniprot id: A0A2Z6ETJ2
names: Similarity
messages: Belongs to the SCO1/2 family.

1553431:MCB1EB RS01220
gene id: 1553431:MCB1EB_RS01220
uniprot id: A0A2Z6ESL0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1553431:MCB1EB RS10470
gene id: 1553431:MCB1EB_RS10470
uniprot id: A0A2Z6EXN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS05740
gene id: 1553431:MCB1EB_RS05740
uniprot id: A0A2Z6EUY5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1553431:MCB1EB RS05020
gene id: 1553431:MCB1EB_RS05020
uniprot id: A0A2Z6EUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRR-containing bacterial E3 ligase family.
messages: Host cytoplasm
messages: Secreted

1553431:MCB1EB RS09540
gene id: 1553431:MCB1EB_RS09540
uniprot id: A0A2Z6EY28
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS02620
gene id: 1553431:MCB1EB_RS02620
uniprot id: A0A2Z6ETE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1553431:MCB1EB RS03125
gene id: 1553431:MCB1EB_RS03125
uniprot id: A0A2Z6ETM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

1553431:MCB1EB RS10200
gene id: 1553431:MCB1EB_RS10200
uniprot id: A0A2Z6EXM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1553431:MCB1EB RS01795
gene id: 1553431:MCB1EB_RS01795
uniprot id: A0A2Z6ET06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1553431:MCB1EB RS01885
gene id: 1553431:MCB1EB_RS01885
uniprot id: A0A2Z6ESZ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1553431:MCB1EB RS10720
gene id: 1553431:MCB1EB_RS10720
uniprot id: A0A2Z6EYI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1553431:MCB1EB RS03730
gene id: 1553431:MCB1EB_RS03730
uniprot id: A0A2Z6ETV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1553431:MCB1EB RS06155
gene id: 1553431:MCB1EB_RS06155
uniprot id: A0A2Z6EV92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS11100
gene id: 1553431:MCB1EB_RS11100
uniprot id: A0A2Z6EY02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS05670
gene id: 1553431:MCB1EB_RS05670
uniprot id: A0A2Z6EUW2
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS08640
gene id: 1553431:MCB1EB_RS08640
uniprot id: A0A2Z6EWM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Membrane

1553431:MCB1EB RS00315
gene id: 1553431:MCB1EB_RS00315
uniprot id: A0A2Z6ES46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1553431:MCB1EB RS01595
gene id: 1553431:MCB1EB_RS01595
uniprot id: A0A2Z6ESS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1553431:MCB1EB RS05895
gene id: 1553431:MCB1EB_RS05895
uniprot id: A0A2Z6EV71
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS01350
gene id: 1553431:MCB1EB_RS01350
uniprot id: A0A2Z6ESR3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1553431:MCB1EB RS09600
gene id: 1553431:MCB1EB_RS09600
uniprot id: A0A2Z6EX83
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1553431:MCB1EB RS01060
gene id: 1553431:MCB1EB_RS01060
uniprot id: A0A2Z6ESI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1553431:MCB1EB RS06385
gene id: 1553431:MCB1EB_RS06385
uniprot id: A0A2Z6EVI5
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS09145
gene id: 1553431:MCB1EB_RS09145
uniprot id: A0A2Z6EWW8
names: Subcellular Location Annotation
messages: Membrane

1553431:MCB1EB RS00200
gene id: 1553431:MCB1EB_RS00200
uniprot id: A0A2Z6ES30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS09165
gene id: 1553431:MCB1EB_RS09165
uniprot id: A0A2Z6EWY1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1553431:MCB1EB RS03080
gene id: 1553431:MCB1EB_RS03080
uniprot id: A0A2Z6ETM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane

1553431:MCB1EB RS02370
gene id: 1553431:MCB1EB_RS02370
uniprot id: A0A2Z6ETB6
names: Similarity
messages: Belongs to the PhoH family.

1553431:MCB1EB RS01470
gene id: 1553431:MCB1EB_RS01470
uniprot id: A0A2Z6ESR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

1553431:MCB1EB RS04415
gene id: 1553431:MCB1EB_RS04415
uniprot id: A0A2Z6EUD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1553431:MCB1EB RS12220
gene id: 1553431:MCB1EB_RS12220
uniprot id: A0A2Z6EY16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1553431:MCB1EB RS09250
gene id: 1553431:MCB1EB_RS09250
uniprot id: A0A2Z6EXX5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1553431:MCB1EB RS03350
gene id: 1553431:MCB1EB_RS03350
uniprot id: A0A2Z6ETS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1553431:MCB1EB RS00715
gene id: 1553431:MCB1EB_RS00715
uniprot id: A0A2Z6ESC7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1553431:MCB1EB RS02925
gene id: 1553431:MCB1EB_RS02925
uniprot id: A0A2Z6ETJ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1553431:MCB1EB RS06115
gene id: 1553431:MCB1EB_RS06115
uniprot id: A0A2Z6EVD9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1553431:MCB1EB RS03330
gene id: 1553431:MCB1EB_RS03330
uniprot id: A0A2Z6ETQ9
names: Similarity
messages: Belongs to the lipid A palmitoyltransferase family.

1553431:MCB1EB RS08625
gene id: 1553431:MCB1EB_RS08625
uniprot id: A0A2Z6EWQ4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1553431:MCB1EB RS09520
gene id: 1553431:MCB1EB_RS09520
uniprot id: A0A2Z6EX47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1553431:MCB1EB RS06410
gene id: 1553431:MCB1EB_RS06410
uniprot id: A0A2Z6EVH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1553431:MCB1EB RS10070
gene id: 1553431:MCB1EB_RS10070
uniprot id: A0A2Z6EXI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1553431:MCB1EB RS05345
gene id: 1553431:MCB1EB_RS05345
uniprot id: A0A2Z6EUS2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1553431:MCB1EB RS02805
gene id: 1553431:MCB1EB_RS02805
uniprot id: A0A2Z6ETF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1553431:MCB1EB RS06365
gene id: 1553431:MCB1EB_RS06365
uniprot id: A0A2Z6EVF9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1553431:MCB1EB RS08575
gene id: 1553431:MCB1EB_RS08575
uniprot id: A0A2Z6EXK1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1553431:MCB1EB RS05480
gene id: 1553431:MCB1EB_RS05480
uniprot id: A0A2Z6EVV6
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1553431:MCB1EB RS07100
gene id: 1553431:MCB1EB_RS07100
uniprot id: A0A2Z6EVV3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1553431:MCB1EB RS10150
gene id: 1553431:MCB1EB_RS10150
uniprot id: A0A2Z6EXL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1553431:MCB1EB RS04650
gene id: 1553431:MCB1EB_RS04650
uniprot id: A0A2Z6EUG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1553431:MCB1EB RS11040
gene id: 1553431:MCB1EB_RS11040
uniprot id: A0A2Z6EXY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1553431:MCB1EB RS10730
gene id: 1553431:MCB1EB_RS10730
uniprot id: A0A2Z6EXW2
names: Similarity
messages: Belongs to the UPF0758 family.

1553431:MCB1EB RS10495
gene id: 1553431:MCB1EB_RS10495
uniprot id: A0A2Z6EXP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1553431:MCB1EB RS01920
gene id: 1553431:MCB1EB_RS01920
uniprot id: A0A2Z6ESZ4
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1553431:MCB1EB RS05625
gene id: 1553431:MCB1EB_RS05625
uniprot id: A0A2Z6EUX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1553431:MCB1EB RS08635
gene id: 1553431:MCB1EB_RS08635
uniprot id: A0A2Z6EWT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1553431:MCB1EB RS03760
gene id: 1553431:MCB1EB_RS03760
uniprot id: A0A2Z6ETZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1553431:MCB1EB RS04360
gene id: 1553431:MCB1EB_RS04360
uniprot id: A0A2Z6EU81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS11665
gene id: 1553431:MCB1EB_RS11665
uniprot id: A0A2Z6EYH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1553431:MCB1EB RS11685
gene id: 1553431:MCB1EB_RS11685
uniprot id: A0A2Z6EYG3
names: Similarity
messages: Belongs to the UPF0102 family.

1553431:MCB1EB RS01045
gene id: 1553431:MCB1EB_RS01045
uniprot id: A0A2Z6ESI6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1553431:MCB1EB RS10090
gene id: 1553431:MCB1EB_RS10090
uniprot id: A0A2Z6EXG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1553431:MCB1EB RS01265
gene id: 1553431:MCB1EB_RS01265
uniprot id: A0A2Z6ESM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1553431:MCB1EB RS00440
gene id: 1553431:MCB1EB_RS00440
uniprot id: A0A2Z6ES85
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1553431:MCB1EB RS00425
gene id: 1553431:MCB1EB_RS00425
uniprot id: A0A2Z6ES62
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1553431:MCB1EB RS12555
gene id: 1553431:MCB1EB_RS12555
uniprot id: A0A2Z6EXD2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1553431:MCB1EB RS10275
gene id: 1553431:MCB1EB_RS10275
uniprot id: A0A2Z6EXM2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1553431:MCB1EB RS00280
gene id: 1553431:MCB1EB_RS00280
uniprot id: A0A2Z6ES37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1553431:MCB1EB RS03715
gene id: 1553431:MCB1EB_RS03715
uniprot id: A0A2Z6EU12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1553431:MCB1EB RS01355
gene id: 1553431:MCB1EB_RS01355
uniprot id: A0A2Z6ESQ0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1553431:MCB1EB RS07170
gene id: 1553431:MCB1EB_RS07170
uniprot id: A0A2Z6EVR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1553431:MCB1EB RS05170
gene id: 1553431:MCB1EB_RS05170
uniprot id: A0A2Z6EUN8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1553431:MCB1EB RS00735
gene id: 1553431:MCB1EB_RS00735
uniprot id: A0A2Z6ESC5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1553431:MCB1EB RS00385
gene id: 1553431:MCB1EB_RS00385
uniprot id: A0A2Z6ES61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.