1550241:MA03 RS03865
gene id: 1550241:MA03_RS03865
uniprot id: A0A0F7FIS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1550241:MA03 RS07820
gene id: 1550241:MA03_RS07820
uniprot id: A0A0F7FIS1
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1550241:MA03 RS05855
gene id: 1550241:MA03_RS05855
uniprot id: A0A0F7FJ44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

1550241:MA03 RS07415
gene id: 1550241:MA03_RS07415
uniprot id: A0A0F7FJB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1550241:MA03 RS01175
gene id: 1550241:MA03_RS01175
uniprot id: A0A0F7FG49
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1550241:MA03 RS02140
gene id: 1550241:MA03_RS02140
uniprot id: A0A0F7FHU8
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS04280
gene id: 1550241:MA03_RS04280
uniprot id: A0A0F7FJ56
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.

1550241:MA03 RS08335
gene id: 1550241:MA03_RS08335
uniprot id: A0A0F7FIM7
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1550241:MA03 RS00350
gene id: 1550241:MA03_RS00350
uniprot id: A0A0F7FH64
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1550241:MA03 RS05865
gene id: 1550241:MA03_RS05865
uniprot id: A0A0F7FIW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1550241:MA03 RS06195
gene id: 1550241:MA03_RS06195
uniprot id: A0A0F7CL75
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

1550241:MA03 RS07490
gene id: 1550241:MA03_RS07490
uniprot id: A0A0F7FJL7
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1550241:MA03 RS03760
gene id: 1550241:MA03_RS03760
uniprot id: A0A0F7CLF9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1550241:MA03 RS03810
gene id: 1550241:MA03_RS03810
uniprot id: A0A0F7FHF4
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS02155
gene id: 1550241:MA03_RS02155
uniprot id: A0A0F7FIT5
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS04545
gene id: 1550241:MA03_RS04545
uniprot id: A0A0F7FHM7
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS08330
gene id: 1550241:MA03_RS08330
uniprot id: A0A0F7FIX6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1550241:MA03 RS03985
gene id: 1550241:MA03_RS03985
uniprot id: A0A0F7FH61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1550241:MA03 RS01755
gene id: 1550241:MA03_RS01755
uniprot id: A0A0F7FGK1
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS04095
gene id: 1550241:MA03_RS04095
uniprot id: A0A0F7FH72
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1550241:MA03 RS05955
gene id: 1550241:MA03_RS05955
uniprot id: A0A0F7FHT2
names: Subcellular Location Annotation
messages: Nucleus

1550241:MA03 RS06750
gene id: 1550241:MA03_RS06750
uniprot id: A0A0F7CL91
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

1550241:MA03 RS01435
gene id: 1550241:MA03_RS01435
uniprot id: A0A0F7CLE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1550241:MA03 RS04040
gene id: 1550241:MA03_RS04040
uniprot id: A0A0F7FHA7
names: Similarity
messages: Belongs to the CTP synthase family.

1550241:MA03 RS08160
gene id: 1550241:MA03_RS08160
uniprot id: A0A0F7CLD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1550241:MA03 RS05535
gene id: 1550241:MA03_RS05535
uniprot id: A0A0F7FJY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

1550241:MA03 RS06405
gene id: 1550241:MA03_RS06405
uniprot id: A0A0F7FI14
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1550241:MA03 RS07400
gene id: 1550241:MA03_RS07400
uniprot id: A0A0F7FJK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

1550241:MA03 RS00820
gene id: 1550241:MA03_RS00820
uniprot id: A0A0F7FHC9
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS05585
gene id: 1550241:MA03_RS05585
uniprot id: A0A0F7CL59
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1550241:MA03 RS02175
gene id: 1550241:MA03_RS02175
uniprot id: A0A0F7FGV0
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS06570
gene id: 1550241:MA03_RS06570
uniprot id: A0A0F7FKB1
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1550241:MA03 RS06915
gene id: 1550241:MA03_RS06915
uniprot id: A0A0F7FII2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

1550241:MA03 RS00700
gene id: 1550241:MA03_RS00700
uniprot id: A0A0F7FG88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1550241:MA03 RS06755
gene id: 1550241:MA03_RS06755
uniprot id: A0A0F7FI08
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

1550241:MA03 RS07675
gene id: 1550241:MA03_RS07675
uniprot id: A0A0F7FJE3
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1550241:MA03 RS07630
gene id: 1550241:MA03_RS07630
uniprot id: A0A0F7FIQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

1550241:MA03 RS07735
gene id: 1550241:MA03_RS07735
uniprot id: A0A0F7FIR2
names: Similarity
messages: Belongs to the SDO1/SBDS family.

1550241:MA03 RS04735
gene id: 1550241:MA03_RS04735
uniprot id: A0A0F7CLG5
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

1550241:MA03 RS00695
gene id: 1550241:MA03_RS00695
uniprot id: A0A0F7FGZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1550241:MA03 RS05870
gene id: 1550241:MA03_RS05870
uniprot id: A0A0F7CL66
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

1550241:MA03 RS06025
gene id: 1550241:MA03_RS06025
uniprot id: A0A0F7FJ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1550241:MA03 RS00555
gene id: 1550241:MA03_RS00555
uniprot id: A0A0F7FH86
names: Similarity
messages: Belongs to the peptidase U62 family.

1550241:MA03 RS08220
gene id: 1550241:MA03_RS08220
uniprot id: A0A0F7FIL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

1550241:MA03 RS00605
gene id: 1550241:MA03_RS00605
uniprot id: A0A0F7FG45
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS03285
gene id: 1550241:MA03_RS03285
uniprot id: A0A0F7FH81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1550241:MA03 RS06825
gene id: 1550241:MA03_RS06825
uniprot id: A0A0F7FIH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1550241:MA03 RS05910
gene id: 1550241:MA03_RS05910
uniprot id: A0A0F7FJ50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1550241:MA03 RS02875
gene id: 1550241:MA03_RS02875
uniprot id: A0A0F7FHS1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1550241:MA03 RS07060
gene id: 1550241:MA03_RS07060
uniprot id: A0A0F7CLA0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1550241:MA03 RS02940
gene id: 1550241:MA03_RS02940
uniprot id: A0A0F7FGY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

1550241:MA03 RS07405
gene id: 1550241:MA03_RS07405
uniprot id: A0A0F7CLB1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1550241:MA03 RS00170
gene id: 1550241:MA03_RS00170
uniprot id: A0A0F7FFZ5
names: Similarity
messages: Belongs to the archease family.

1550241:MA03 RS00390
gene id: 1550241:MA03_RS00390
uniprot id: A0A0F7FG55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1550241:MA03 RS01140
gene id: 1550241:MA03_RS01140
uniprot id: A0A0F7FG46
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1550241:MA03 RS04225
gene id: 1550241:MA03_RS04225
uniprot id: A0A0F7FH83
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS01545
gene id: 1550241:MA03_RS01545
uniprot id: A0A0F7FGM8
names: Similarity
messages: Belongs to the AOR/FOR family.

1550241:MA03 RS08460
gene id: 1550241:MA03_RS08460
uniprot id: A0A0F7FJM1
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1550241:MA03 RS00550
gene id: 1550241:MA03_RS00550
uniprot id: A0A0F7CKQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1550241:MA03 RS04840
gene id: 1550241:MA03_RS04840
uniprot id: A0A0F7FHG9
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1550241:MA03 RS00490
gene id: 1550241:MA03_RS00490
uniprot id: A0A0F7FH78
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS04315
gene id: 1550241:MA03_RS04315
uniprot id: A0A0F7CL23
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS00100
gene id: 1550241:MA03_RS00100
uniprot id: A0A0F7FIK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1550241:MA03 RS07685
gene id: 1550241:MA03_RS07685
uniprot id: A0A0F7CLB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

1550241:MA03 RS04595
gene id: 1550241:MA03_RS04595
uniprot id: A0A0F7FIP6
names: Similarity
messages: Belongs to the HypE family.

1550241:MA03 RS02760
gene id: 1550241:MA03_RS02760
uniprot id: A0A0F7CKX2
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS05295
gene id: 1550241:MA03_RS05295
uniprot id: A0A0F7FHJ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1550241:MA03 RS00620
gene id: 1550241:MA03_RS00620
uniprot id: A0A0F7FG80
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

1550241:MA03 RS08350
gene id: 1550241:MA03_RS08350
uniprot id: A0A0F7FII7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1550241:MA03 RS07410
gene id: 1550241:MA03_RS07410
uniprot id: A0A0F7FI85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1550241:MA03 RS02905
gene id: 1550241:MA03_RS02905
uniprot id: A0A0F7FHS5
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1550241:MA03 RS03220
gene id: 1550241:MA03_RS03220
uniprot id: A0A0F7FI78
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1550241:MA03 RS06865
gene id: 1550241:MA03_RS06865
uniprot id: A0A0F7FIH6
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1550241:MA03 RS02685
gene id: 1550241:MA03_RS02685
uniprot id: A0A0F7FH05
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS06625
gene id: 1550241:MA03_RS06625
uniprot id: A0A0F7CL88
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1550241:MA03 RS00335
gene id: 1550241:MA03_RS00335
uniprot id: A0A0F7FG48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1550241:MA03 RS03185
gene id: 1550241:MA03_RS03185
uniprot id: A0A0F7FI77
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1550241:MA03 RS02450
gene id: 1550241:MA03_RS02450
uniprot id: A0A0F7FHM3
names: Subcellular Location Annotation
messages: Cell membrane

1550241:MA03 RS04375
gene id: 1550241:MA03_RS04375
uniprot id: A0A0F7FIM5
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS00340
gene id: 1550241:MA03_RS00340
uniprot id: A0A0F7FFU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1550241:MA03 RS06845
gene id: 1550241:MA03_RS06845
uniprot id: A0A0F7FJE2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1550241:MA03 RS00600
gene id: 1550241:MA03_RS00600
uniprot id: A0A0F7FH90
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1550241:MA03 RS00225
gene id: 1550241:MA03_RS00225
uniprot id: A0A0F7FGS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1550241:MA03 RS02660
gene id: 1550241:MA03_RS02660
uniprot id: A0A0F7FHP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1550241:MA03 RS03595
gene id: 1550241:MA03_RS03595
uniprot id: A0A0F7FI07
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS07730
gene id: 1550241:MA03_RS07730
uniprot id: A0A0F7FJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

1550241:MA03 RS04495
gene id: 1550241:MA03_RS04495
uniprot id: A0A0F7FHM4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

1550241:MA03 RS00345
gene id: 1550241:MA03_RS00345
uniprot id: A0A0F7FJZ1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1550241:MA03 RS00775
gene id: 1550241:MA03_RS00775
uniprot id: A0A0F7FG11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1550241:MA03 RS07910
gene id: 1550241:MA03_RS07910
uniprot id: A0A0F7FJG3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1550241:MA03 RS05505
gene id: 1550241:MA03_RS05505
uniprot id: A0A0F7FI29
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1550241:MA03 RS05265
gene id: 1550241:MA03_RS05265
uniprot id: A0A0F7FIM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1550241:MA03 RS06860
gene id: 1550241:MA03_RS06860
uniprot id: A0A0F7CL94
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1550241:MA03 RS02340
gene id: 1550241:MA03_RS02340
uniprot id: A0A0F7FHX2
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS03915
gene id: 1550241:MA03_RS03915
uniprot id: A0A0F7FIG9
names: Similarity
messages: Belongs to the UPF0145 family.

1550241:MA03 RS05435
gene id: 1550241:MA03_RS05435
uniprot id: A0A0F7CL55
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS01370
gene id: 1550241:MA03_RS01370
uniprot id: A0A0F7CKT2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

1550241:MA03 RS01475
gene id: 1550241:MA03_RS01475
uniprot id: A0A0F7FHM9
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1550241:MA03 RS05760
gene id: 1550241:MA03_RS05760
uniprot id: A0A0F7FIW3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1550241:MA03 RS04120
gene id: 1550241:MA03_RS04120
uniprot id: A0A0F7FHA9
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1550241:MA03 RS00315
gene id: 1550241:MA03_RS00315
uniprot id: A0A0F7FH59
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1550241:MA03 RS06470
gene id: 1550241:MA03_RS06470
uniprot id: A0A0F7FJ18
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS07745
gene id: 1550241:MA03_RS07745
uniprot id: A0A0F7FJP9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs.

1550241:MA03 RS00310
gene id: 1550241:MA03_RS00310
uniprot id: A0A0F7FFU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1550241:MA03 RS00190
gene id: 1550241:MA03_RS00190
uniprot id: A0A0F7FG33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1550241:MA03 RS05930
gene id: 1550241:MA03_RS05930
uniprot id: A0A0F7FI73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1550241:MA03 RS00855
gene id: 1550241:MA03_RS00855
uniprot id: A0A0F7FHD5
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

1550241:MA03 RS02965
gene id: 1550241:MA03_RS02965
uniprot id: A0A0F7FGT1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1550241:MA03 RS06540
gene id: 1550241:MA03_RS06540
uniprot id: A0A0F7CL86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1550241:MA03 RS06640
gene id: 1550241:MA03_RS06640
uniprot id: A0A0F7FJC7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1550241:MA03 RS05640
gene id: 1550241:MA03_RS05640
uniprot id: A0A0F7FK97
names: Similarity
messages: Belongs to the UPF0273 family.

1550241:MA03 RS07435
gene id: 1550241:MA03_RS07435
uniprot id: A0A0F7CLB2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1550241:MA03 RS00825
gene id: 1550241:MA03_RS00825
uniprot id: A0A0F7CKR6
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS05525
gene id: 1550241:MA03_RS05525
uniprot id: A0A0F7FHP3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1550241:MA03 RS06015
gene id: 1550241:MA03_RS06015
uniprot id: A0A0F7FI87
names: Similarity
messages: Belongs to the PGI/PMI family.

1550241:MA03 RS00130
gene id: 1550241:MA03_RS00130
uniprot id: A0A0F7FGR5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

1550241:MA03 RS05895
gene id: 1550241:MA03_RS05895
uniprot id: A0A0F7CL67
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS08265
gene id: 1550241:MA03_RS08265
uniprot id: A0A0F7FJV9
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1550241:MA03 RS00735
gene id: 1550241:MA03_RS00735
uniprot id: A0A0F7CKR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1550241:MA03 RS00420
gene id: 1550241:MA03_RS00420
uniprot id: A0A0F7FG22
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1550241:MA03 RS04245
gene id: 1550241:MA03_RS04245
uniprot id: A0A0F7FHB2
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS00090
gene id: 1550241:MA03_RS00090
uniprot id: A0A0F7CLE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1550241:MA03 RS04125
gene id: 1550241:MA03_RS04125
uniprot id: A0A0F7FI82
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1550241:MA03 RS03645
gene id: 1550241:MA03_RS03645
uniprot id: A0A0F7FID5
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1550241:MA03 RS06660
gene id: 1550241:MA03_RS06660
uniprot id: A0A0F7FHZ9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1550241:MA03 RS03335
gene id: 1550241:MA03_RS03335
uniprot id: A0A0F7FH31
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS00180
gene id: 1550241:MA03_RS00180
uniprot id: A0A0F7CKP5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1550241:MA03 RS02500
gene id: 1550241:MA03_RS02500
uniprot id: A0A0F7FGY5
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS00195
gene id: 1550241:MA03_RS00195
uniprot id: A0A0F7FFT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1550241:MA03 RS02555
gene id: 1550241:MA03_RS02555
uniprot id: A0A0F7CKW6
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1550241:MA03 RS08075
gene id: 1550241:MA03_RS08075
uniprot id: A0A0F7FIF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

1550241:MA03 RS03460
gene id: 1550241:MA03_RS03460
uniprot id: A0A0F7FHZ4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1550241:MA03 RS08425
gene id: 1550241:MA03_RS08425
uniprot id: A0A0F7FJX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1550241:MA03 RS00500
gene id: 1550241:MA03_RS00500
uniprot id: A0A0F7CKQ5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1550241:MA03 RS07095
gene id: 1550241:MA03_RS07095
uniprot id: A0A0F7FI84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1550241:MA03 RS05075
gene id: 1550241:MA03_RS05075
uniprot id: A0A0F7FHH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1550241:MA03 RS07010
gene id: 1550241:MA03_RS07010
uniprot id: A0A0F7FI36
names: Similarity
messages: Belongs to the UMP kinase family.

1550241:MA03 RS07750
gene id: 1550241:MA03_RS07750
uniprot id: A0A0F7FKG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

1550241:MA03 RS07845
gene id: 1550241:MA03_RS07845
uniprot id: A0A0F7FJQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

1550241:MA03 RS06565
gene id: 1550241:MA03_RS06565
uniprot id: A0A0F7FIF0
names: Similarity
messages: Belongs to the RutC family.

1550241:MA03 RS00410
gene id: 1550241:MA03_RS00410
uniprot id: A0A0F7FH68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

1550241:MA03 RS00385
gene id: 1550241:MA03_RS00385
uniprot id: A0A0F7FGU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

1550241:MA03 RS02610
gene id: 1550241:MA03_RS02610
uniprot id: A0A0F7CKW7
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

1550241:MA03 RS01625
gene id: 1550241:MA03_RS01625
uniprot id: A0A0F7CKT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1550241:MA03 RS01260
gene id: 1550241:MA03_RS01260
uniprot id: A0A0F7FHL4
names: Similarity
messages: Belongs to the peptidase U62 family.

1550241:MA03 RS01570
gene id: 1550241:MA03_RS01570
uniprot id: A0A0F7FK19
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1550241:MA03 RS06985
gene id: 1550241:MA03_RS06985
uniprot id: A0A0F7FJ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

1550241:MA03 RS04425
gene id: 1550241:MA03_RS04425
uniprot id: A0A0F7FHC1
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

1550241:MA03 RS03875
gene id: 1550241:MA03_RS03875
uniprot id: A0A0F7FIG3
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS07990
gene id: 1550241:MA03_RS07990
uniprot id: A0A0F7FIE9
names: Similarity
messages: Belongs to the UPF0111 family.

1550241:MA03 RS01655
gene id: 1550241:MA03_RS01655
uniprot id: A0A0F7CKU0
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

1550241:MA03 RS07610
gene id: 1550241:MA03_RS07610
uniprot id: A0A0F7FIA9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1550241:MA03 RS06745
gene id: 1550241:MA03_RS06745
uniprot id: A0A0F7FJD3
names: Similarity
messages: Belongs to the PDCD5 family.

1550241:MA03 RS04555
gene id: 1550241:MA03_RS04555
uniprot id: A0A0F7FHC8
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS04535
gene id: 1550241:MA03_RS04535
uniprot id: A0A0F7CL29
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Membrane

1550241:MA03 RS04285
gene id: 1550241:MA03_RS04285
uniprot id: A0A0F7FIL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1550241:MA03 RS04860
gene id: 1550241:MA03_RS04860
uniprot id: A0A0F7FHG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1550241:MA03 RS07740
gene id: 1550241:MA03_RS07740
uniprot id: A0A0F7FIG5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1550241:MA03 RS07455
gene id: 1550241:MA03_RS07455
uniprot id: A0A0F7FI92
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1550241:MA03 RS01145
gene id: 1550241:MA03_RS01145
uniprot id: A0A0F7FHG6
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS08155
gene id: 1550241:MA03_RS08155
uniprot id: A0A0F7FJ65
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

1550241:MA03 RS03250
gene id: 1550241:MA03_RS03250
uniprot id: A0A0F7FGW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1550241:MA03 RS05090
gene id: 1550241:MA03_RS05090
uniprot id: A0A0F7CL45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1550241:MA03 RS08115
gene id: 1550241:MA03_RS08115
uniprot id: A0A0F7FJU2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1550241:MA03 RS00200
gene id: 1550241:MA03_RS00200
uniprot id: A0A0F7FH45
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

1550241:MA03 RS02545
gene id: 1550241:MA03_RS02545
uniprot id: A0A0F7FHZ2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1550241:MA03 RS03030
gene id: 1550241:MA03_RS03030
uniprot id: A0A0F7CKY2
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS03855
gene id: 1550241:MA03_RS03855
uniprot id: A0A0F7FH46
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS00230
gene id: 1550241:MA03_RS00230
uniprot id: A0A0F7FG36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1550241:MA03 RS01205
gene id: 1550241:MA03_RS01205
uniprot id: A0A0F7FG89
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

1550241:MA03 RS05250
gene id: 1550241:MA03_RS05250
uniprot id: A0A0F7FIX2
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

1550241:MA03 RS07345
gene id: 1550241:MA03_RS07345
uniprot id: A0A0F7FJK0
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1550241:MA03 RS07665
gene id: 1550241:MA03_RS07665
uniprot id: A0A0F7FJN7
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1550241:MA03 RS02560
gene id: 1550241:MA03_RS02560
uniprot id: A0A0F7FIQ3
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS00400
gene id: 1550241:MA03_RS00400
uniprot id: A0A0F7CKQ2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1550241:MA03 RS04510
gene id: 1550241:MA03_RS04510
uniprot id: A0A0F7FHC2
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1550241:MA03 RS03015
gene id: 1550241:MA03_RS03015
uniprot id: A0A0F7FHU1
names: Similarity
messages: Belongs to the peptidase S8 family.

1550241:MA03 RS00355
gene id: 1550241:MA03_RS00355
uniprot id: A0A0F7FIL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1550241:MA03 RS00850
gene id: 1550241:MA03_RS00850
uniprot id: A0A0F7CKR7
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

1550241:MA03 RS00050
gene id: 1550241:MA03_RS00050
uniprot id: A0A0F7FIP0
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1550241:MA03 RS05880
gene id: 1550241:MA03_RS05880
uniprot id: A0A0F7FIX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1550241:MA03 RS04175
gene id: 1550241:MA03_RS04175
uniprot id: A0A0F7FH79
names: Similarity
messages: Belongs to the DtxR/MntR family.

1550241:MA03 RS00730
gene id: 1550241:MA03_RS00730
uniprot id: A0A0F7FG93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1550241:MA03 RS00575
gene id: 1550241:MA03_RS00575
uniprot id: A0A0F7FJN5
names: Similarity
messages: Belongs to the carbamate kinase family.

1550241:MA03 RS06220
gene id: 1550241:MA03_RS06220
uniprot id: A0A0F7FHZ3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

1550241:MA03 RS03180
gene id: 1550241:MA03_RS03180
uniprot id: A0A0F7CKY7
names: Similarity
messages: Belongs to the peptidase M1 family.

1550241:MA03 RS08015
gene id: 1550241:MA03_RS08015
uniprot id: A0A0F7CLI0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

1550241:MA03 RS03545
gene id: 1550241:MA03_RS03545
uniprot id: A0A0F7FI03
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS02065
gene id: 1550241:MA03_RS02065
uniprot id: A0A0F7FHU3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1550241:MA03 RS07330
gene id: 1550241:MA03_RS07330
uniprot id: A0A0F7FIN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

1550241:MA03 RS06850
gene id: 1550241:MA03_RS06850
uniprot id: A0A0F7FI16
names: Similarity
messages: Belongs to the SUI1 family.

1550241:MA03 RS04020
gene id: 1550241:MA03_RS04020
uniprot id: A0A0F7FIW5
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1550241:MA03 RS01270
gene id: 1550241:MA03_RS01270
uniprot id: A0A0F7FHA5
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1550241:MA03 RS05180
gene id: 1550241:MA03_RS05180
uniprot id: A0A0F7FHI2
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1550241:MA03 RS08235
gene id: 1550241:MA03_RS08235
uniprot id: A0A0F7FIH2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1550241:MA03 RS02305
gene id: 1550241:MA03_RS02305
uniprot id: A0A0F7FHW8
names: Function
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

1550241:MA03 RS06695
gene id: 1550241:MA03_RS06695
uniprot id: A0A0F7FI41
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS07480
gene id: 1550241:MA03_RS07480
uniprot id: A0A0F7CLB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

1550241:MA03 RS04050
gene id: 1550241:MA03_RS04050
uniprot id: A0A0F7FI68
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS05305
gene id: 1550241:MA03_RS05305
uniprot id: A0A0F7FIR0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1550241:MA03 RS06840
gene id: 1550241:MA03_RS06840
uniprot id: A0A0F7FI56
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

1550241:MA03 RS01990
gene id: 1550241:MA03_RS01990
uniprot id: A0A0F7FGM5
names: Similarity
messages: Belongs to the HypD family.

1550241:MA03 RS02095
gene id: 1550241:MA03_RS02095
uniprot id: A0A0F7FHJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1550241:MA03 RS02205
gene id: 1550241:MA03_RS02205
uniprot id: A0A0F7FHK5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1550241:MA03 RS02570
gene id: 1550241:MA03_RS02570
uniprot id: A0A0F7FGT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1550241:MA03 RS00185
gene id: 1550241:MA03_RS00185
uniprot id: A0A0F7FGS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

1550241:MA03 RS06515
gene id: 1550241:MA03_RS06515
uniprot id: A0A0F7CL85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1550241:MA03 RS05380
gene id: 1550241:MA03_RS05380
uniprot id: A0A0F7FJ85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1550241:MA03 RS04800
gene id: 1550241:MA03_RS04800
uniprot id: A0A0F7FIG1
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS07005
gene id: 1550241:MA03_RS07005
uniprot id: A0A0F7FJF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

1550241:MA03 RS04650
gene id: 1550241:MA03_RS04650
uniprot id: A0A0F7FHE8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

1550241:MA03 RS07035
gene id: 1550241:MA03_RS07035
uniprot id: A0A0F7FJG2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1550241:MA03 RS00025
gene id: 1550241:MA03_RS00025
uniprot id: A0A0F7FH29
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1550241:MA03 RS06710
gene id: 1550241:MA03_RS06710
uniprot id: A0A0F7FI04
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

1550241:MA03 RS07880
gene id: 1550241:MA03_RS07880
uniprot id: A0A0F7FIS6
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

1550241:MA03 RS08310
gene id: 1550241:MA03_RS08310
uniprot id: A0A0F7CLD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1550241:MA03 RS03975
gene id: 1550241:MA03_RS03975
uniprot id: A0A0F7FHI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1550241:MA03 RS02380
gene id: 1550241:MA03_RS02380
uniprot id: A0A0F7FGK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1550241:MA03 RS00110
gene id: 1550241:MA03_RS00110
uniprot id: A0A0F7FH35
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

1550241:MA03 RS06590
gene id: 1550241:MA03_RS06590
uniprot id: A0A0F7FJC3
names: Similarity
messages: Belongs to the UPF0047 family.

1550241:MA03 RS07015
gene id: 1550241:MA03_RS07015
uniprot id: A0A0F7FJ67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1550241:MA03 RS05800
gene id: 1550241:MA03_RS05800
uniprot id: A0A0F7FHV4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

1550241:MA03 RS08045
gene id: 1550241:MA03_RS08045
uniprot id: A0A0F7FIU5
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1550241:MA03 RS05335
gene id: 1550241:MA03_RS05335
uniprot id: A0A0F7CL52
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1550241:MA03 RS00375
gene id: 1550241:MA03_RS00375
uniprot id: A0A0F7FG17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

1550241:MA03 RS00085
gene id: 1550241:MA03_RS00085
uniprot id: A0A0F7CKP3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1550241:MA03 RS05695
gene id: 1550241:MA03_RS05695
uniprot id: A0A0F7CL62
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1550241:MA03 RS04330
gene id: 1550241:MA03_RS04330
uniprot id: A0A0F7CLG2
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS07420
gene id: 1550241:MA03_RS07420
uniprot id: A0A0F7FIN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

1550241:MA03 RS06530
gene id: 1550241:MA03_RS06530
uniprot id: A0A0F7FI28
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

1550241:MA03 RS00465
gene id: 1550241:MA03_RS00465
uniprot id: A0A0F7FG26
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

1550241:MA03 RS02375
gene id: 1550241:MA03_RS02375
uniprot id: A0A0F7FGX0
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS04015
gene id: 1550241:MA03_RS04015
uniprot id: A0A0F7CL14
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1550241:MA03 RS01630
gene id: 1550241:MA03_RS01630
uniprot id: A0A0F7FGP0
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1550241:MA03 RS08000
gene id: 1550241:MA03_RS08000
uniprot id: A0A0F7FIU0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1550241:MA03 RS04755
gene id: 1550241:MA03_RS04755
uniprot id: A0A0F7FHP8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1550241:MA03 RS02695
gene id: 1550241:MA03_RS02695
uniprot id: A0A0F7FI06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1550241:MA03 RS07450
gene id: 1550241:MA03_RS07450
uniprot id: A0A0F7FJL2
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

1550241:MA03 RS03570
gene id: 1550241:MA03_RS03570
uniprot id: A0A0F7FH07
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1550241:MA03 RS01560
gene id: 1550241:MA03_RS01560
uniprot id: A0A0F7FHN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1550241:MA03 RS00120
gene id: 1550241:MA03_RS00120
uniprot id: A0A0F7FJM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

1550241:MA03 RS06975
gene id: 1550241:MA03_RS06975
uniprot id: A0A0F7FJF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1550241:MA03 RS00890
gene id: 1550241:MA03_RS00890
uniprot id: A0A0F7FG24
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1550241:MA03 RS05950
gene id: 1550241:MA03_RS05950
uniprot id: A0A0F7FJA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1550241:MA03 RS00320
gene id: 1550241:MA03_RS00320
uniprot id: A0A0F7FG12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1550241:MA03 RS03120
gene id: 1550241:MA03_RS03120
uniprot id: A0A0F7CKY5
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS05770
gene id: 1550241:MA03_RS05770
uniprot id: A0A0F7FIZ8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1550241:MA03 RS06420
gene id: 1550241:MA03_RS06420
uniprot id: A0A0F7FJA3
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1550241:MA03 RS06580
gene id: 1550241:MA03_RS06580
uniprot id: A0A0F7CL87
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1550241:MA03 RS06700
gene id: 1550241:MA03_RS06700
uniprot id: A0A0F7FJD0
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

1550241:MA03 RS03005
gene id: 1550241:MA03_RS03005
uniprot id: A0A0F7CKY1
names: Function
names: Similarity
messages: Belongs to the UPF0330 family.
messages: Possibly the antitoxin component of a toxin-antitoxin (TA) module.

1550241:MA03 RS06780
gene id: 1550241:MA03_RS06780
uniprot id: A0A0F7FKB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

1550241:MA03 RS02150
gene id: 1550241:MA03_RS02150
uniprot id: A0A0F7FGN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1550241:MA03 RS05115
gene id: 1550241:MA03_RS05115
uniprot id: A0A0F7FIK1
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS03540
gene id: 1550241:MA03_RS03540
uniprot id: A0A0F7FH56
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS06090
gene id: 1550241:MA03_RS06090
uniprot id: A0A0F7FJ66
names: Similarity
messages: Belongs to the UPF0201 family.

1550241:MA03 RS06295
gene id: 1550241:MA03_RS06295
uniprot id: A0A0F7FIB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1550241:MA03 RS01865
gene id: 1550241:MA03_RS01865
uniprot id: A0A0F7FGS0
names: Similarity
messages: Belongs to the HupF/HypC family.

1550241:MA03 RS07885
gene id: 1550241:MA03_RS07885
uniprot id: A0A0F7FII0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1550241:MA03 RS03365
gene id: 1550241:MA03_RS03365
uniprot id: A0A0F7FIA1
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS00830
gene id: 1550241:MA03_RS00830
uniprot id: A0A0F7FG72
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1550241:MA03 RS05655
gene id: 1550241:MA03_RS05655
uniprot id: A0A0F7CL61
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1550241:MA03 RS06550
gene id: 1550241:MA03_RS06550
uniprot id: A0A0F7FHZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1550241:MA03 RS08150
gene id: 1550241:MA03_RS08150
uniprot id: A0A0F7FIK7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

1550241:MA03 RS05340
gene id: 1550241:MA03_RS05340
uniprot id: A0A0F7FJ08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1550241:MA03 RS00160
gene id: 1550241:MA03_RS00160
uniprot id: A0A0F7FH40
names: Similarity
messages: Belongs to the MEMO1 family.

1550241:MA03 RS04760
gene id: 1550241:MA03_RS04760
uniprot id: A0A0F7FHF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1550241:MA03 RS00425
gene id: 1550241:MA03_RS00425
uniprot id: A0A0F7FGV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

1550241:MA03 RS07765
gene id: 1550241:MA03_RS07765
uniprot id: A0A0F7FIC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

1550241:MA03 RS07465
gene id: 1550241:MA03_RS07465
uniprot id: A0A0F7FJC1
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

1550241:MA03 RS06215
gene id: 1550241:MA03_RS06215
uniprot id: A0A0F7FIA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

1550241:MA03 RS00440
gene id: 1550241:MA03_RS00440
uniprot id: A0A0F7CKQ3
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1550241:MA03 RS06525
gene id: 1550241:MA03_RS06525
uniprot id: A0A0F7FIE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1550241:MA03 RS08255
gene id: 1550241:MA03_RS08255
uniprot id: A0A0F7FIL8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

1550241:MA03 RS05875
gene id: 1550241:MA03_RS05875
uniprot id: A0A0F7FHS2
names: Similarity
messages: Belongs to the eIF-2-alpha family.

1550241:MA03 RS08205
gene id: 1550241:MA03_RS08205
uniprot id: A0A0F7FIV8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1550241:MA03 RS01225
gene id: 1550241:MA03_RS01225
uniprot id: A0A0F7FGE9
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS05920
gene id: 1550241:MA03_RS05920
uniprot id: A0A0F7FIX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

1550241:MA03 RS07815
gene id: 1550241:MA03_RS07815
uniprot id: A0A0F7FJF6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1550241:MA03 RS02405
gene id: 1550241:MA03_RS02405
uniprot id: A0A0F7FHM0
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS04865
gene id: 1550241:MA03_RS04865
uniprot id: A0A0F7FIS3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1550241:MA03 RS02335
gene id: 1550241:MA03_RS02335
uniprot id: A0A0F7FGK4
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS01055
gene id: 1550241:MA03_RS01055
uniprot id: A0A0F7CKS2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1550241:MA03 RS00925
gene id: 1550241:MA03_RS00925
uniprot id: A0A0F7FJP0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1550241:MA03 RS00245
gene id: 1550241:MA03_RS00245
uniprot id: A0A0F7CKP7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1550241:MA03 RS04875
gene id: 1550241:MA03_RS04875
uniprot id: A0A0F7FHH2
names: Similarity
messages: Belongs to the UPF0111 family.

1550241:MA03 RS06605
gene id: 1550241:MA03_RS06605
uniprot id: A0A0F7FIF3
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS02315
gene id: 1550241:MA03_RS02315
uniprot id: A0A0F7FHL5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1550241:MA03 RS01760
gene id: 1550241:MA03_RS01760
uniprot id: A0A0F7FHG7
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1550241:MA03 RS06430
gene id: 1550241:MA03_RS06430
uniprot id: A0A0F7FJ14
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

1550241:MA03 RS03400
gene id: 1550241:MA03_RS03400
uniprot id: A0A0F7FIA6
names: Function
names: Similarity
messages: Belongs to the LuxC family.
messages: LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.

1550241:MA03 RS05130
gene id: 1550241:MA03_RS05130
uniprot id: A0A0F7FIV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1550241:MA03 RS05345
gene id: 1550241:MA03_RS05345
uniprot id: A0A0F7FHM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1550241:MA03 RS04490
gene id: 1550241:MA03_RS04490
uniprot id: A0A0F7FIX3
names: Similarity
messages: Belongs to the acylphosphatase family.

1550241:MA03 RS00615
gene id: 1550241:MA03_RS00615
uniprot id: A0A0F7CKQ9
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

1550241:MA03 RS02600
gene id: 1550241:MA03_RS02600
uniprot id: A0A0F7FIU6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1550241:MA03 RS08080
gene id: 1550241:MA03_RS08080
uniprot id: A0A0F7CLD0
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

1550241:MA03 RS03620
gene id: 1550241:MA03_RS03620
uniprot id: A0A0F7FH63
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

1550241:MA03 RS00115
gene id: 1550241:MA03_RS00115
uniprot id: A0A0F7FFZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

1550241:MA03 RS05785
gene id: 1550241:MA03_RS05785
uniprot id: A0A0F7FKA0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1550241:MA03 RS00795
gene id: 1550241:MA03_RS00795
uniprot id: A0A0F7CKR5
names: Similarity
messages: Belongs to the Nth/MutY family.

1550241:MA03 RS06600
gene id: 1550241:MA03_RS06600
uniprot id: A0A0F7FJ29
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS00300
gene id: 1550241:MA03_RS00300
uniprot id: A0A0F7CKP9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1550241:MA03 RS05400
gene id: 1550241:MA03_RS05400
uniprot id: A0A0F7CL54
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1550241:MA03 RS03205
gene id: 1550241:MA03_RS03205
uniprot id: A0A0F7CKY8
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS05915
gene id: 1550241:MA03_RS05915
uniprot id: A0A0F7FHS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1550241:MA03 RS07720
gene id: 1550241:MA03_RS07720
uniprot id: A0A0F7FIC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

1550241:MA03 RS05790
gene id: 1550241:MA03_RS05790
uniprot id: A0A0F7CL64
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1550241:MA03 RS00140
gene id: 1550241:MA03_RS00140
uniprot id: A0A0F7FG27
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1550241:MA03 RS04790
gene id: 1550241:MA03_RS04790
uniprot id: A0A0F7FIY2
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1550241:MA03 RS04925
gene id: 1550241:MA03_RS04925
uniprot id: A0A0F7CL40
names: Similarity
messages: Belongs to the RuvB family.

1550241:MA03 RS07930
gene id: 1550241:MA03_RS07930
uniprot id: A0A0F7CLC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

1550241:MA03 RS06035
gene id: 1550241:MA03_RS06035
uniprot id: A0A0F7CL71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1550241:MA03 RS00330
gene id: 1550241:MA03_RS00330
uniprot id: A0A0F7FGU2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

1550241:MA03 RS04745
gene id: 1550241:MA03_RS04745
uniprot id: A0A0F7CL35
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1550241:MA03 RS08165
gene id: 1550241:MA03_RS08165
uniprot id: A0A0F7FJU9
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

1550241:MA03 RS02115
gene id: 1550241:MA03_RS02115
uniprot id: A0A0F7FGI1
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1550241:MA03 RS00815
gene id: 1550241:MA03_RS00815
uniprot id: A0A0F7FG15
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1550241:MA03 RS07495
gene id: 1550241:MA03_RS07495
uniprot id: A0A0F7FI95
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS06855
gene id: 1550241:MA03_RS06855
uniprot id: A0A0F7FJ49
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1550241:MA03 RS01620
gene id: 1550241:MA03_RS01620
uniprot id: A0A0F7FIN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1550241:MA03 RS08280
gene id: 1550241:MA03_RS08280
uniprot id: A0A0F7FJK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1550241:MA03 RS06270
gene id: 1550241:MA03_RS06270
uniprot id: A0A0F7FJ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1550241:MA03 RS05060
gene id: 1550241:MA03_RS05060
uniprot id: A0A0F7FHJ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

1550241:MA03 RS07395
gene id: 1550241:MA03_RS07395
uniprot id: A0A0F7FJ43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1550241:MA03 RS05705
gene id: 1550241:MA03_RS05705
uniprot id: A0A0F7FJ33
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

1550241:MA03 RS06765
gene id: 1550241:MA03_RS06765
uniprot id: A0A0F7FJ41
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1550241:MA03 RS01975
gene id: 1550241:MA03_RS01975
uniprot id: A0A0F7FGG8
names: Subcellular Location Annotation
messages: Membrane

1550241:MA03 RS05860
gene id: 1550241:MA03_RS05860
uniprot id: A0A0F7CLH1
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

1550241:MA03 RS07045
gene id: 1550241:MA03_RS07045
uniprot id: A0A0F7FI42
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

1550241:MA03 RS05460
gene id: 1550241:MA03_RS05460
uniprot id: A0A0F7FHR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

1550241:MA03 RS07485
gene id: 1550241:MA03_RS07485
uniprot id: A0A0F7FID2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

1550241:MA03 RS07725
gene id: 1550241:MA03_RS07725
uniprot id: A0A0F7CLC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

1550241:MA03 RS08105
gene id: 1550241:MA03_RS08105
uniprot id: A0A0F7FIK2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1550241:MA03 RS04845
gene id: 1550241:MA03_RS04845
uniprot id: A0A0F7FIG6
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1550241:MA03 RS07785
gene id: 1550241:MA03_RS07785
uniprot id: A0A0F7FIR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

1550241:MA03 RS05850
gene id: 1550241:MA03_RS05850
uniprot id: A0A0F7FHV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

1550241:MA03 RS04350
gene id: 1550241:MA03_RS04350
uniprot id: A0A0F7FIA7
names: Similarity
messages: Belongs to the complex I subunit 3 family.

1550241:MA03 RS05290
gene id: 1550241:MA03_RS05290
uniprot id: A0A0F7CL51
names: Similarity
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.

1550241:MA03 RS06965
gene id: 1550241:MA03_RS06965
uniprot id: A0A0F7CL97
names: Similarity
messages: Belongs to the CTAG/PCC1 family.