1549855:AY555 RS00785
gene id: 1549855:AY555_RS00785
uniprot id: A0A143DBI5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1549855:AY555 RS11380
gene id: 1549855:AY555_RS11380
uniprot id: A0A143DGB4
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1549855:AY555 RS08995
gene id: 1549855:AY555_RS08995
uniprot id: A0A143DHJ1
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1549855:AY555 RS03550
gene id: 1549855:AY555_RS03550
uniprot id: A0A143DCF5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1549855:AY555 RS06955
gene id: 1549855:AY555_RS06955
uniprot id: A0A143DEF0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS00640
gene id: 1549855:AY555_RS00640
uniprot id: A0A143DB39
names: Similarity
messages: Belongs to the UPF0758 family.

1549855:AY555 RS10270
gene id: 1549855:AY555_RS10270
uniprot id: A0A143DGB4
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1549855:AY555 RS05370
gene id: 1549855:AY555_RS05370
uniprot id: A0A143DDT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1549855:AY555 RS08230
gene id: 1549855:AY555_RS08230
uniprot id: A0A143DEH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1549855:AY555 RS08325
gene id: 1549855:AY555_RS08325
uniprot id: A0A143DGE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1549855:AY555 RS01000
gene id: 1549855:AY555_RS01000
uniprot id: A0A143DBM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1549855:AY555 RS02255
gene id: 1549855:AY555_RS02255
uniprot id: A0A143DD42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1549855:AY555 RS00155
gene id: 1549855:AY555_RS00155
uniprot id: A0A143DBE6
names: Subcellular Location Annotation
messages: Periplasm

1549855:AY555 RS08090
gene id: 1549855:AY555_RS08090
uniprot id: A0A143DEG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1549855:AY555 RS00230
gene id: 1549855:AY555_RS00230
uniprot id: A0A143DFF5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1549855:AY555 RS02990
gene id: 1549855:AY555_RS02990
uniprot id: A0A143DC58
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549855:AY555 RS00315
gene id: 1549855:AY555_RS00315
uniprot id: A0A143DAW9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

1549855:AY555 RS00605
gene id: 1549855:AY555_RS00605
uniprot id: A0A143DCS4
names: Similarity
messages: Belongs to the histone deacetylase family.

1549855:AY555 RS03495
gene id: 1549855:AY555_RS03495
uniprot id: A0A143DCG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1549855:AY555 RS04740
gene id: 1549855:AY555_RS04740
uniprot id: A0A143DFN8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1549855:AY555 RS08385
gene id: 1549855:AY555_RS08385
uniprot id: A0A143DEU2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1549855:AY555 RS11230
gene id: 1549855:AY555_RS11230
uniprot id: A0A143DGM2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1549855:AY555 RS05535
gene id: 1549855:AY555_RS05535
uniprot id: A0A143DDQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1549855:AY555 RS08680
gene id: 1549855:AY555_RS08680
uniprot id: A0A143DET5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1549855:AY555 RS04795
gene id: 1549855:AY555_RS04795
uniprot id: A0A143DER5
names: Similarity
messages: Belongs to the Dps family.

1549855:AY555 RS06200
gene id: 1549855:AY555_RS06200
uniprot id: A0A143DFG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1549855:AY555 RS07480
gene id: 1549855:AY555_RS07480
uniprot id: A0A143DET6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1549855:AY555 RS06120
gene id: 1549855:AY555_RS06120
uniprot id: A0A143DDU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS01310
gene id: 1549855:AY555_RS01310
uniprot id: A0A143DCN7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1549855:AY555 RS08100
gene id: 1549855:AY555_RS08100
uniprot id: A0A143DFS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1549855:AY555 RS03225
gene id: 1549855:AY555_RS03225
uniprot id: A0A143DCB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1549855:AY555 RS07730
gene id: 1549855:AY555_RS07730
uniprot id: A0A143DFM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

1549855:AY555 RS03510
gene id: 1549855:AY555_RS03510
uniprot id: A0A143DFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1549855:AY555 RS04445
gene id: 1549855:AY555_RS04445
uniprot id: A0A143DH76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1549855:AY555 RS05810
gene id: 1549855:AY555_RS05810
uniprot id: A0A143DER7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549855:AY555 RS00340
gene id: 1549855:AY555_RS00340
uniprot id: A0A143DAZ9
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1549855:AY555 RS05105
gene id: 1549855:AY555_RS05105
uniprot id: A0A143DG87
names: Similarity
messages: Belongs to the GARS family.

1549855:AY555 RS06855
gene id: 1549855:AY555_RS06855
uniprot id: A0A143DE03
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1549855:AY555 RS02500
gene id: 1549855:AY555_RS02500
uniprot id: A0A143DD84
names: Similarity
messages: Belongs to the peptidase U62 family.

1549855:AY555 RS08745
gene id: 1549855:AY555_RS08745
uniprot id: A0A143DEV7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1549855:AY555 RS04735
gene id: 1549855:AY555_RS04735
uniprot id: A0A143DEQ5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1549855:AY555 RS05245
gene id: 1549855:AY555_RS05245
uniprot id: A0A143DDK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

1549855:AY555 RS10355
gene id: 1549855:AY555_RS10355
uniprot id: A0A143DGB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1549855:AY555 RS03415
gene id: 1549855:AY555_RS03415
uniprot id: A0A143DCR4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1549855:AY555 RS01270
gene id: 1549855:AY555_RS01270
uniprot id: A0A143DBC0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1549855:AY555 RS10615
gene id: 1549855:AY555_RS10615
uniprot id: A0A145VQ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1549855:AY555 RS01525
gene id: 1549855:AY555_RS01525
uniprot id: A0A143DD73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1549855:AY555 RS11250
gene id: 1549855:AY555_RS11250
uniprot id: A0A145VSC1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1549855:AY555 RS01335
gene id: 1549855:AY555_RS01335
uniprot id: A0A143DBK6
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

1549855:AY555 RS07570
gene id: 1549855:AY555_RS07570
uniprot id: A0A143DEA3
names: Similarity
messages: Belongs to the hemerythrin family.

1549855:AY555 RS09495
gene id: 1549855:AY555_RS09495
uniprot id: A0A143DF54
names: Subcellular Location Annotation
messages: Cytoplasm

1549855:AY555 RS04865
gene id: 1549855:AY555_RS04865
uniprot id: A0A143DDF2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS03255
gene id: 1549855:AY555_RS03255
uniprot id: A0A143DE22
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1549855:AY555 RS06615
gene id: 1549855:AY555_RS06615
uniprot id: A0A143DDX1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS07600
gene id: 1549855:AY555_RS07600
uniprot id: A0A143DEQ2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1549855:AY555 RS11350
gene id: 1549855:AY555_RS11350
uniprot id: A0A143DH71
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1549855:AY555 RS08315
gene id: 1549855:AY555_RS08315
uniprot id: A0A143DES9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1549855:AY555 RS06815
gene id: 1549855:AY555_RS06815
uniprot id: A0A143DFR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1549855:AY555 RS04020
gene id: 1549855:AY555_RS04020
uniprot id: A0A143DCN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1549855:AY555 RS07760
gene id: 1549855:AY555_RS07760
uniprot id: A0A143DED9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1549855:AY555 RS04360
gene id: 1549855:AY555_RS04360
uniprot id: A0A143DFX6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1549855:AY555 RS09565
gene id: 1549855:AY555_RS09565
uniprot id: A0A143DFF6
names: Similarity
messages: Belongs to the BolA/IbaG family.

1549855:AY555 RS00260
gene id: 1549855:AY555_RS00260
uniprot id: A0A143DCL4
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1549855:AY555 RS07440
gene id: 1549855:AY555_RS07440
uniprot id: A0A143DFH8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS10625
gene id: 1549855:AY555_RS10625
uniprot id: A0A145VQ74
names: Similarity
messages: Belongs to the thioesterase family.

1549855:AY555 RS09175
gene id: 1549855:AY555_RS09175
uniprot id: A0A143DF80
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1549855:AY555 RS12285
gene id: 1549855:AY555_RS12285
uniprot id: A0A145VQR2
names: Subcellular Location Annotation
messages: Secreted

1549855:AY555 RS00060
gene id: 1549855:AY555_RS00060
uniprot id: A0A143DAU9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1549855:AY555 RS10780
gene id: 1549855:AY555_RS10780
uniprot id: A0A143DGR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1549855:AY555 RS05275
gene id: 1549855:AY555_RS05275
uniprot id: A0A143DEH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1549855:AY555 RS09680
gene id: 1549855:AY555_RS09680
uniprot id: A0A143DF74
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1549855:AY555 RS03210
gene id: 1549855:AY555_RS03210
uniprot id: A0A143DCM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1549855:AY555 RS04250
gene id: 1549855:AY555_RS04250
uniprot id: A0A143DCP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1549855:AY555 RS09535
gene id: 1549855:AY555_RS09535
uniprot id: A0A143DF72
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1549855:AY555 RS00755
gene id: 1549855:AY555_RS00755
uniprot id: A0A143DB36
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1549855:AY555 RS05750
gene id: 1549855:AY555_RS05750
uniprot id: A0A143DEQ8
names: Similarity
messages: Belongs to the universal stress protein A family.

1549855:AY555 RS01350
gene id: 1549855:AY555_RS01350
uniprot id: A0A143DBS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1549855:AY555 RS01950
gene id: 1549855:AY555_RS01950
uniprot id: A0A143DBQ0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1549855:AY555 RS03810
gene id: 1549855:AY555_RS03810
uniprot id: A0A143DCJ3
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1549855:AY555 RS10790
gene id: 1549855:AY555_RS10790
uniprot id: A0A143DGZ8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

1549855:AY555 RS01595
gene id: 1549855:AY555_RS01595
uniprot id: A0A143DD79
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1549855:AY555 RS07495
gene id: 1549855:AY555_RS07495
uniprot id: A0A143DFI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1549855:AY555 RS00950
gene id: 1549855:AY555_RS00950
uniprot id: A0A143DBL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1549855:AY555 RS09200
gene id: 1549855:AY555_RS09200
uniprot id: A0A143DF06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1549855:AY555 RS05870
gene id: 1549855:AY555_RS05870
uniprot id: A0A143DES6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1549855:AY555 RS08885
gene id: 1549855:AY555_RS08885
uniprot id: A0A143DFA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1549855:AY555 RS07805
gene id: 1549855:AY555_RS07805
uniprot id: A0A143DEB1
names: Similarity
messages: Belongs to the Skp family.

1549855:AY555 RS00515
gene id: 1549855:AY555_RS00515
uniprot id: A0A143DB27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1549855:AY555 RS00995
gene id: 1549855:AY555_RS00995
uniprot id: A0A143DCZ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1549855:AY555 RS07655
gene id: 1549855:AY555_RS07655
uniprot id: A0A143DER4
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS09635
gene id: 1549855:AY555_RS09635
uniprot id: A0A143DFG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS06780
gene id: 1549855:AY555_RS06780
uniprot id: A0A143DDV8
names: Similarity
messages: Belongs to the peptidase S49 family.

1549855:AY555 RS08255
gene id: 1549855:AY555_RS08255
uniprot id: A0A143DEM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1549855:AY555 RS00765
gene id: 1549855:AY555_RS00765
uniprot id: A0A143DBC1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1549855:AY555 RS07050
gene id: 1549855:AY555_RS07050
uniprot id: A0A143DEL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549855:AY555 RS05890
gene id: 1549855:AY555_RS05890
uniprot id: A0A143DDJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1549855:AY555 RS02545
gene id: 1549855:AY555_RS02545
uniprot id: A0A143DBX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1549855:AY555 RS02395
gene id: 1549855:AY555_RS02395
uniprot id: A0A143DDL5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1549855:AY555 RS07070
gene id: 1549855:AY555_RS07070
uniprot id: A0A143DFC4
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1549855:AY555 RS02390
gene id: 1549855:AY555_RS02390
uniprot id: A0A143DBU9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1549855:AY555 RS08895
gene id: 1549855:AY555_RS08895
uniprot id: A0A143DEW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1549855:AY555 RS10600
gene id: 1549855:AY555_RS10600
uniprot id: A0A145VQ08
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1549855:AY555 RS03545
gene id: 1549855:AY555_RS03545
uniprot id: A0A143DDQ7
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1549855:AY555 RS00855
gene id: 1549855:AY555_RS00855
uniprot id: A0A143DB84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1549855:AY555 RS00690
gene id: 1549855:AY555_RS00690
uniprot id: A0A143DCD7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1549855:AY555 RS09595
gene id: 1549855:AY555_RS09595
uniprot id: A0A143DFY0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1549855:AY555 RS02405
gene id: 1549855:AY555_RS02405
uniprot id: A0A143DCF6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1549855:AY555 RS03115
gene id: 1549855:AY555_RS03115
uniprot id: A0A143DC86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1549855:AY555 RS09820
gene id: 1549855:AY555_RS09820
uniprot id: A0A143DFY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1549855:AY555 RS04835
gene id: 1549855:AY555_RS04835
uniprot id: A0A143DD28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1549855:AY555 RS08200
gene id: 1549855:AY555_RS08200
uniprot id: A0A143DFZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1549855:AY555 RS00575
gene id: 1549855:AY555_RS00575
uniprot id: A0A143DCB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1549855:AY555 RS06065
gene id: 1549855:AY555_RS06065
uniprot id: A0A143DDR9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS04320
gene id: 1549855:AY555_RS04320
uniprot id: A0A143DCS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1549855:AY555 RS08175
gene id: 1549855:AY555_RS08175
uniprot id: A0A143DEJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1549855:AY555 RS09090
gene id: 1549855:AY555_RS09090
uniprot id: A0A143DFZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1549855:AY555 RS07065
gene id: 1549855:AY555_RS07065
uniprot id: A0A143DFR7
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1549855:AY555 RS06950
gene id: 1549855:AY555_RS06950
uniprot id: A0A143DFS9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1549855:AY555 RS09860
gene id: 1549855:AY555_RS09860
uniprot id: A0A143DFW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1549855:AY555 RS04050
gene id: 1549855:AY555_RS04050
uniprot id: A0A143DG60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1549855:AY555 RS01650
gene id: 1549855:AY555_RS01650
uniprot id: A0A143DBH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1549855:AY555 RS06090
gene id: 1549855:AY555_RS06090
uniprot id: A0A143DDJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1549855:AY555 RS00355
gene id: 1549855:AY555_RS00355
uniprot id: A0A143DFY1
names: Similarity
messages: Belongs to the peptidase U62 family.

1549855:AY555 RS06245
gene id: 1549855:AY555_RS06245
uniprot id: A0A143DF03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1549855:AY555 RS04035
gene id: 1549855:AY555_RS04035
uniprot id: A0A143DD76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1549855:AY555 RS09425
gene id: 1549855:AY555_RS09425
uniprot id: A0A143DGE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cytoplasm

1549855:AY555 RS07695
gene id: 1549855:AY555_RS07695
uniprot id: A0A143DEI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS08015
gene id: 1549855:AY555_RS08015
uniprot id: A0A143DEX5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1549855:AY555 RS09385
gene id: 1549855:AY555_RS09385
uniprot id: A0A143DF41
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

1549855:AY555 RS01160
gene id: 1549855:AY555_RS01160
uniprot id: A0A143DFH6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1549855:AY555 RS03435
gene id: 1549855:AY555_RS03435
uniprot id: A0A143DDN5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1549855:AY555 RS00990
gene id: 1549855:AY555_RS00990
uniprot id: A0A143DB82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1549855:AY555 RS06670
gene id: 1549855:AY555_RS06670
uniprot id: A0A143DF68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1549855:AY555 RS08610
gene id: 1549855:AY555_RS08610
uniprot id: A0A143DG07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1549855:AY555 RS09815
gene id: 1549855:AY555_RS09815
uniprot id: A0A143DF93
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1549855:AY555 RS09895
gene id: 1549855:AY555_RS09895
uniprot id: A0A143DFK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1549855:AY555 RS11080
gene id: 1549855:AY555_RS11080
uniprot id: A0A145VRU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10B family.
messages: Secreted

1549855:AY555 RS08905
gene id: 1549855:AY555_RS08905
uniprot id: A0A143DG54
names: Subcellular Location Annotation
messages: Cell membrane

1549855:AY555 RS00505
gene id: 1549855:AY555_RS00505
uniprot id: A0A143DBK4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1549855:AY555 RS00450
gene id: 1549855:AY555_RS00450
uniprot id: A0A143DFC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1549855:AY555 RS00500
gene id: 1549855:AY555_RS00500
uniprot id: A0A143DBD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1549855:AY555 RS03530
gene id: 1549855:AY555_RS03530
uniprot id: A0A143DFM5
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS09605
gene id: 1549855:AY555_RS09605
uniprot id: A0A143DF84
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1549855:AY555 RS08940
gene id: 1549855:AY555_RS08940
uniprot id: A0A143DFH1
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS06215
gene id: 1549855:AY555_RS06215
uniprot id: A0A143DE93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1549855:AY555 RS07795
gene id: 1549855:AY555_RS07795
uniprot id: A0A143DEY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1549855:AY555 RS06070
gene id: 1549855:AY555_RS06070
uniprot id: A0A143DDM8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1549855:AY555 RS11265
gene id: 1549855:AY555_RS11265
uniprot id: A0A145VSE0
names: Similarity
messages: Belongs to the ParB family.

1549855:AY555 RS09235
gene id: 1549855:AY555_RS09235
uniprot id: A0A143DGQ7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1549855:AY555 RS00070
gene id: 1549855:AY555_RS00070
uniprot id: A0A143DB14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1549855:AY555 RS03585
gene id: 1549855:AY555_RS03585
uniprot id: A0A143DCU6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS10990
gene id: 1549855:AY555_RS10990
uniprot id: A0A145VRH8
names: Similarity
messages: Belongs to the FemABX family.

1549855:AY555 RS03270
gene id: 1549855:AY555_RS03270
uniprot id: A0A143DCP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1549855:AY555 RS11205
gene id: 1549855:AY555_RS11205
uniprot id: A0A145VS82
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1549855:AY555 RS08105
gene id: 1549855:AY555_RS08105
uniprot id: A0A143DEJ0
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1549855:AY555 RS08755
gene id: 1549855:AY555_RS08755
uniprot id: A0A143DF88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549855:AY555 RS07620
gene id: 1549855:AY555_RS07620
uniprot id: A0A143DFK4
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1549855:AY555 RS09230
gene id: 1549855:AY555_RS09230
uniprot id: A0A143DF34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1549855:AY555 RS05220
gene id: 1549855:AY555_RS05220
uniprot id: A0A143DD85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1549855:AY555 RS05965
gene id: 1549855:AY555_RS05965
uniprot id: A0A143DE41
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1549855:AY555 RS02670
gene id: 1549855:AY555_RS02670
uniprot id: A0A143DDB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1549855:AY555 RS01140
gene id: 1549855:AY555_RS01140
uniprot id: A0A143DBA0
names: Similarity
messages: Belongs to the peptidase M24B family.

1549855:AY555 RS00875
gene id: 1549855:AY555_RS00875
uniprot id: A0A143DFX3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1549855:AY555 RS02360
gene id: 1549855:AY555_RS02360
uniprot id: A0A143DBU3
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

1549855:AY555 RS06680
gene id: 1549855:AY555_RS06680
uniprot id: A0A143DDV9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1549855:AY555 RS07335
gene id: 1549855:AY555_RS07335
uniprot id: A0A143DE66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1549855:AY555 RS01375
gene id: 1549855:AY555_RS01375
uniprot id: A0A143DBE4
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1549855:AY555 RS02430
gene id: 1549855:AY555_RS02430
uniprot id: A0A143DD71
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1549855:AY555 RS02995
gene id: 1549855:AY555_RS02995
uniprot id: A0A143DC68
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1549855:AY555 RS04800
gene id: 1549855:AY555_RS04800
uniprot id: A0A143DDD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1549855:AY555 RS00405
gene id: 1549855:AY555_RS00405
uniprot id: A0A143DB07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1549855:AY555 RS06825
gene id: 1549855:AY555_RS06825
uniprot id: A0A143DED1
names: Similarity
messages: Belongs to the aspartokinase family.

1549855:AY555 RS04190
gene id: 1549855:AY555_RS04190
uniprot id: A0A143DFN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1549855:AY555 RS09725
gene id: 1549855:AY555_RS09725
uniprot id: A0A143DGI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1549855:AY555 RS00610
gene id: 1549855:AY555_RS00610
uniprot id: A0A143DFC6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1549855:AY555 RS01345
gene id: 1549855:AY555_RS01345
uniprot id: A0A143DD45
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1549855:AY555 RS02135
gene id: 1549855:AY555_RS02135
uniprot id: A0A143DFK0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1549855:AY555 RS02560
gene id: 1549855:AY555_RS02560
uniprot id: A0A143DBZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

1549855:AY555 RS05285
gene id: 1549855:AY555_RS05285
uniprot id: A0A143DD96
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1549855:AY555 RS10210
gene id: 1549855:AY555_RS10210
uniprot id: A0A143DC71
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1549855:AY555 RS02070
gene id: 1549855:AY555_RS02070
uniprot id: A0A143DD13
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549855:AY555 RS02535
gene id: 1549855:AY555_RS02535
uniprot id: A0A143DCB3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1549855:AY555 RS04055
gene id: 1549855:AY555_RS04055
uniprot id: A0A143DDZ3
names: Function
messages: Multidrug efflux pump.

1549855:AY555 RS01455
gene id: 1549855:AY555_RS01455
uniprot id: A0A143DBE5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1549855:AY555 RS10920
gene id: 1549855:AY555_RS10920
uniprot id: A0A143DGI4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1549855:AY555 RS09940
gene id: 1549855:AY555_RS09940
uniprot id: A0A143DFX1
names: Similarity
messages: Belongs to the virb1 family.

1549855:AY555 RS02640
gene id: 1549855:AY555_RS02640
uniprot id: A0A143DCD4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1549855:AY555 RS04615
gene id: 1549855:AY555_RS04615
uniprot id: A0A143DE86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1549855:AY555 RS00250
gene id: 1549855:AY555_RS00250
uniprot id: A0A143DAV9
names: Similarity
messages: Belongs to the virb1 family.

1549855:AY555 RS09450
gene id: 1549855:AY555_RS09450
uniprot id: A0A143DF75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1549855:AY555 RS06210
gene id: 1549855:AY555_RS06210
uniprot id: A0A143DE35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1549855:AY555 RS07110
gene id: 1549855:AY555_RS07110
uniprot id: A0A143DE01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1549855:AY555 RS00915
gene id: 1549855:AY555_RS00915
uniprot id: A0A143DCH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1549855:AY555 RS08805
gene id: 1549855:AY555_RS08805
uniprot id: A0A143DEW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1549855:AY555 RS00055
gene id: 1549855:AY555_RS00055
uniprot id: A0A143DC06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1549855:AY555 RS01940
gene id: 1549855:AY555_RS01940
uniprot id: A0A143DC81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1549855:AY555 RS07610
gene id: 1549855:AY555_RS07610
uniprot id: A0A143DEV3
names: Similarity
messages: Belongs to the HesB/IscA family.

1549855:AY555 RS09560
gene id: 1549855:AY555_RS09560
uniprot id: A0A143DF63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1549855:AY555 RS00965
gene id: 1549855:AY555_RS00965
uniprot id: A0A143DBA3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1549855:AY555 RS11175
gene id: 1549855:AY555_RS11175
uniprot id: A0A143DH11
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1549855:AY555 RS03170
gene id: 1549855:AY555_RS03170
uniprot id: A0A143DC93
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS11155
gene id: 1549855:AY555_RS11155
uniprot id: A0A145VTE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1549855:AY555 RS00065
gene id: 1549855:AY555_RS00065
uniprot id: A0A143DAT0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1549855:AY555 RS10510
gene id: 1549855:AY555_RS10510
uniprot id: A0A143DGY2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1549855:AY555 RS01180
gene id: 1549855:AY555_RS01180
uniprot id: A0A143DBB7
names: Similarity
messages: Belongs to the MlaA family.

1549855:AY555 RS00170
gene id: 1549855:AY555_RS00170
uniprot id: A0A143DC29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1549855:AY555 RS06255
gene id: 1549855:AY555_RS06255
uniprot id: A0A143DDP5
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1549855:AY555 RS02100
gene id: 1549855:AY555_RS02100
uniprot id: A0A143DC50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1549855:AY555 RS11005
gene id: 1549855:AY555_RS11005
uniprot id: A0A145VRM0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1549855:AY555 RS00825
gene id: 1549855:AY555_RS00825
uniprot id: A0A143DBD2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1549855:AY555 RS09550
gene id: 1549855:AY555_RS09550
uniprot id: A0A143DGF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1549855:AY555 RS05540
gene id: 1549855:AY555_RS05540
uniprot id: A0A143DDW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1549855:AY555 RS00490
gene id: 1549855:AY555_RS00490
uniprot id: A0A143DAZ8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1549855:AY555 RS04880
gene id: 1549855:AY555_RS04880
uniprot id: A0A143DD20
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1549855:AY555 RS11140
gene id: 1549855:AY555_RS11140
uniprot id: A0A143DHX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1549855:AY555 RS04370
gene id: 1549855:AY555_RS04370
uniprot id: A0A143DEJ6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1549855:AY555 RS04280
gene id: 1549855:AY555_RS04280
uniprot id: A0A143DCU0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1549855:AY555 RS11075
gene id: 1549855:AY555_RS11075
uniprot id: A0A145VTB3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1549855:AY555 RS08130
gene id: 1549855:AY555_RS08130
uniprot id: A0A143DGB3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1549855:AY555 RS00935
gene id: 1549855:AY555_RS00935
uniprot id: A0A143DBE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1549855:AY555 RS09170
gene id: 1549855:AY555_RS09170
uniprot id: A0A143DF00
names: Similarity
messages: Belongs to the peptidase S41A family.

1549855:AY555 RS10655
gene id: 1549855:AY555_RS10655
uniprot id: A0A145VQ96
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS01080
gene id: 1549855:AY555_RS01080
uniprot id: A0A143DBU6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1549855:AY555 RS03775
gene id: 1549855:AY555_RS03775
uniprot id: A0A143DEA9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1549855:AY555 RS06160
gene id: 1549855:AY555_RS06160
uniprot id: A0A143DEZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1549855:AY555 RS10520
gene id: 1549855:AY555_RS10520
uniprot id: A0A143DGE9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549855:AY555 RS01880
gene id: 1549855:AY555_RS01880
uniprot id: A0A143DDD1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549855:AY555 RS08185
gene id: 1549855:AY555_RS08185
uniprot id: A0A143DEJ5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1549855:AY555 RS05305
gene id: 1549855:AY555_RS05305
uniprot id: A0A143DDL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1549855:AY555 RS09585
gene id: 1549855:AY555_RS09585
uniprot id: A0A143DH67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1549855:AY555 RS10385
gene id: 1549855:AY555_RS10385
uniprot id: A0A143DGD3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1549855:AY555 RS05215
gene id: 1549855:AY555_RS05215
uniprot id: A0A143DD63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1549855:AY555 RS10000
gene id: 1549855:AY555_RS10000
uniprot id: A0A143DGD6
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1549855:AY555 RS10305
gene id: 1549855:AY555_RS10305
uniprot id: A0A143DG61
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1549855:AY555 RS10760
gene id: 1549855:AY555_RS10760
uniprot id: A0A143DGL1
names: Subcellular Location Annotation
messages: Cytoplasm

1549855:AY555 RS09345
gene id: 1549855:AY555_RS09345
uniprot id: A0A143DFK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1549855:AY555 RS08900
gene id: 1549855:AY555_RS08900
uniprot id: A0A143DET4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1549855:AY555 RS04025
gene id: 1549855:AY555_RS04025
uniprot id: A0A143DEE1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1549855:AY555 RS09460
gene id: 1549855:AY555_RS09460
uniprot id: A0A143DFM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1549855:AY555 RS03860
gene id: 1549855:AY555_RS03860
uniprot id: A0A143DCK3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1549855:AY555 RS03845
gene id: 1549855:AY555_RS03845
uniprot id: A0A143DCJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1549855:AY555 RS04275
gene id: 1549855:AY555_RS04275
uniprot id: A0A143DCR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

1549855:AY555 RS02310
gene id: 1549855:AY555_RS02310
uniprot id: A0A143DBV7
names: Similarity
messages: Belongs to the PhoH family.

1549855:AY555 RS08190
gene id: 1549855:AY555_RS08190
uniprot id: A0A143DER1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1549855:AY555 RS08595
gene id: 1549855:AY555_RS08595
uniprot id: A0A143DFC1
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1549855:AY555 RS03135
gene id: 1549855:AY555_RS03135
uniprot id: A0A143DC92
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS07075
gene id: 1549855:AY555_RS07075
uniprot id: A0A143DE20
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS04675
gene id: 1549855:AY555_RS04675
uniprot id: A0A143DE96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1549855:AY555 RS00245
gene id: 1549855:AY555_RS00245
uniprot id: A0A143DB41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1549855:AY555 RS03750
gene id: 1549855:AY555_RS03750
uniprot id: A0A143DFL0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS04820
gene id: 1549855:AY555_RS04820
uniprot id: A0A143DD11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1549855:AY555 RS00390
gene id: 1549855:AY555_RS00390
uniprot id: A0A143DBB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1549855:AY555 RS05385
gene id: 1549855:AY555_RS05385
uniprot id: A0A143DEJ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1549855:AY555 RS05155
gene id: 1549855:AY555_RS05155
uniprot id: A0A143DD75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10B family.
messages: Secreted

1549855:AY555 RS00590
gene id: 1549855:AY555_RS00590
uniprot id: A0A143DB88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1549855:AY555 RS00635
gene id: 1549855:AY555_RS00635
uniprot id: A0A143DCC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1549855:AY555 RS05560
gene id: 1549855:AY555_RS05560
uniprot id: A0A143DDC4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1549855:AY555 RS02540
gene id: 1549855:AY555_RS02540
uniprot id: A0A143DCH4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1549855:AY555 RS08475
gene id: 1549855:AY555_RS08475
uniprot id: A0A143DFA4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1549855:AY555 RS06690
gene id: 1549855:AY555_RS06690
uniprot id: A0A143DDY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1549855:AY555 RS03735
gene id: 1549855:AY555_RS03735
uniprot id: A0A143DDU1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1549855:AY555 RS02205
gene id: 1549855:AY555_RS02205
uniprot id: A0A143DBT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1549855:AY555 RS03230
gene id: 1549855:AY555_RS03230
uniprot id: A0A143DDL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1549855:AY555 RS10570
gene id: 1549855:AY555_RS10570
uniprot id: A0A143DGG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1549855:AY555 RS05905
gene id: 1549855:AY555_RS05905
uniprot id: A0A143DE29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS00940
gene id: 1549855:AY555_RS00940
uniprot id: A0A143DB71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1549855:AY555 RS09880
gene id: 1549855:AY555_RS09880
uniprot id: A0A143DFB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1549855:AY555 RS09885
gene id: 1549855:AY555_RS09885
uniprot id: A0A143DFB7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1549855:AY555 RS08750
gene id: 1549855:AY555_RS08750
uniprot id: A0A143DGJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549855:AY555 RS02350
gene id: 1549855:AY555_RS02350
uniprot id: A0A143DC79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1549855:AY555 RS08620
gene id: 1549855:AY555_RS08620
uniprot id: A0A143DER0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS04115
gene id: 1549855:AY555_RS04115
uniprot id: A0A143DCN2
names: Similarity
messages: Belongs to the UPF0162 family.

1549855:AY555 RS10375
gene id: 1549855:AY555_RS10375
uniprot id: A0A143DGC3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1549855:AY555 RS06845
gene id: 1549855:AY555_RS06845
uniprot id: A0A143DF96
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1549855:AY555 RS11320
gene id: 1549855:AY555_RS11320
uniprot id: A0A143DC71
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1549855:AY555 RS08960
gene id: 1549855:AY555_RS08960
uniprot id: A0A143DEX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1549855:AY555 RS08005
gene id: 1549855:AY555_RS08005
uniprot id: A0A143DEI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1549855:AY555 RS11460
gene id: 1549855:AY555_RS11460
uniprot id: A0A143DC71
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1549855:AY555 RS02515
gene id: 1549855:AY555_RS02515
uniprot id: A0A143DBZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1549855:AY555 RS11195
gene id: 1549855:AY555_RS11195
uniprot id: A0A145VS75
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1549855:AY555 RS01790
gene id: 1549855:AY555_RS01790
uniprot id: A0A143DC55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1549855:AY555 RS01985
gene id: 1549855:AY555_RS01985
uniprot id: A0A143DDE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1549855:AY555 RS09350
gene id: 1549855:AY555_RS09350
uniprot id: A0A143DFN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1549855:AY555 RS07100
gene id: 1549855:AY555_RS07100
uniprot id: A0A143DEH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

1549855:AY555 RS00630
gene id: 1549855:AY555_RS00630
uniprot id: A0A143DB46
names: Similarity
messages: Belongs to the SfsA family.

1549855:AY555 RS00325
gene id: 1549855:AY555_RS00325
uniprot id: A0A143DBA8
names: Similarity
messages: Belongs to the UPF0751 family.

1549855:AY555 RS08470
gene id: 1549855:AY555_RS08470
uniprot id: A0A143DF39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549855:AY555 RS02525
gene id: 1549855:AY555_RS02525
uniprot id: A0A143DBW9
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

1549855:AY555 RS01860
gene id: 1549855:AY555_RS01860
uniprot id: A0A143DBN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1549855:AY555 RS03045
gene id: 1549855:AY555_RS03045
uniprot id: A0A143DCR3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1549855:AY555 RS09040
gene id: 1549855:AY555_RS09040
uniprot id: A0A143DF04
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1549855:AY555 RS01640
gene id: 1549855:AY555_RS01640
uniprot id: A0A143DBI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1549855:AY555 RS08250
gene id: 1549855:AY555_RS08250
uniprot id: A0A143DES1
names: Similarity
messages: Belongs to the MotB family.

1549855:AY555 RS07010
gene id: 1549855:AY555_RS07010
uniprot id: A0A143DE08
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1549855:AY555 RS09470
gene id: 1549855:AY555_RS09470
uniprot id: A0A143DF57
names: Similarity
messages: Belongs to the RecJ family.

1549855:AY555 RS09485
gene id: 1549855:AY555_RS09485
uniprot id: A0A143DGF0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1549855:AY555 RS03800
gene id: 1549855:AY555_RS03800
uniprot id: A0A143DCK4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1549855:AY555 RS06695
gene id: 1549855:AY555_RS06695
uniprot id: A0A143DE27
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1549855:AY555 RS03725
gene id: 1549855:AY555_RS03725
uniprot id: A0A143DCH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1549855:AY555 RS08915
gene id: 1549855:AY555_RS08915
uniprot id: A0A143DEV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1549855:AY555 RS03630
gene id: 1549855:AY555_RS03630
uniprot id: A0A143DFK8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1549855:AY555 RS04765
gene id: 1549855:AY555_RS04765
uniprot id: A0A143DEA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1549855:AY555 RS03215
gene id: 1549855:AY555_RS03215
uniprot id: A0A143DCV0
names: Subcellular Location Annotation
messages: Nucleus

1549855:AY555 RS02550
gene id: 1549855:AY555_RS02550
uniprot id: A0A143DBZ7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1549855:AY555 RS05290
gene id: 1549855:AY555_RS05290
uniprot id: A0A143DDD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

1549855:AY555 RS10095
gene id: 1549855:AY555_RS10095
uniprot id: A0A143DG41
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1549855:AY555 RS05340
gene id: 1549855:AY555_RS05340
uniprot id: A0A143DDA6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1549855:AY555 RS04785
gene id: 1549855:AY555_RS04785
uniprot id: A0A143DD10
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1549855:AY555 RS01750
gene id: 1549855:AY555_RS01750
uniprot id: A0A143DBK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1549855:AY555 RS00910
gene id: 1549855:AY555_RS00910
uniprot id: A0A143DB93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1549855:AY555 RS05310
gene id: 1549855:AY555_RS05310
uniprot id: A0A143DDS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1549855:AY555 RS06975
gene id: 1549855:AY555_RS06975
uniprot id: A0A143DDZ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1549855:AY555 RS09780
gene id: 1549855:AY555_RS09780
uniprot id: A0A143DFI1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1549855:AY555 RS05545
gene id: 1549855:AY555_RS05545
uniprot id: A0A143DD99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1549855:AY555 RS09125
gene id: 1549855:AY555_RS09125
uniprot id: A0A143DFF0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1549855:AY555 RS00900
gene id: 1549855:AY555_RS00900
uniprot id: A0A143DBR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1549855:AY555 RS08025
gene id: 1549855:AY555_RS08025
uniprot id: A0A143DEF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1549855:AY555 RS08795
gene id: 1549855:AY555_RS08795
uniprot id: A0A143DET8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1549855:AY555 RS08925
gene id: 1549855:AY555_RS08925
uniprot id: A0A143DEY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS07810
gene id: 1549855:AY555_RS07810
uniprot id: A0A143DEA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1549855:AY555 RS04075
gene id: 1549855:AY555_RS04075
uniprot id: A0A143DCU8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1549855:AY555 RS00565
gene id: 1549855:AY555_RS00565
uniprot id: A0A143DB37
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1549855:AY555 RS07035
gene id: 1549855:AY555_RS07035
uniprot id: A0A143DEG2
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1549855:AY555 RS00960
gene id: 1549855:AY555_RS00960
uniprot id: A0A143DB68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1549855:AY555 RS02620
gene id: 1549855:AY555_RS02620
uniprot id: A0A143DC71
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1549855:AY555 RS02340
gene id: 1549855:AY555_RS02340
uniprot id: A0A143DBU1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1549855:AY555 RS03820
gene id: 1549855:AY555_RS03820
uniprot id: A0A143DCR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1549855:AY555 RS06850
gene id: 1549855:AY555_RS06850
uniprot id: A0A143DDY8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1549855:AY555 RS00475
gene id: 1549855:AY555_RS00475
uniprot id: A0A143DB02
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1549855:AY555 RS06865
gene id: 1549855:AY555_RS06865
uniprot id: A0A143DDZ4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1549855:AY555 RS10380
gene id: 1549855:AY555_RS10380
uniprot id: A0A143DGK7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1549855:AY555 RS06095
gene id: 1549855:AY555_RS06095
uniprot id: A0A143DDM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Belongs to the heat shock protein 70 family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1549855:AY555 RS07990
gene id: 1549855:AY555_RS07990
uniprot id: A0A143DEG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1549855:AY555 RS06660
gene id: 1549855:AY555_RS06660
uniprot id: A0A143DFU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1549855:AY555 RS02290
gene id: 1549855:AY555_RS02290
uniprot id: A0A143DDJ8
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS07305
gene id: 1549855:AY555_RS07305
uniprot id: A0A143DFX0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1549855:AY555 RS11255
gene id: 1549855:AY555_RS11255
uniprot id: A0A145VSD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1549855:AY555 RS09205
gene id: 1549855:AY555_RS09205
uniprot id: A0A143DEY5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1549855:AY555 RS05740
gene id: 1549855:AY555_RS05740
uniprot id: A0A143DDD0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1549855:AY555 RS05865
gene id: 1549855:AY555_RS05865
uniprot id: A0A143DDH5
names: Similarity
messages: Belongs to the fabD family.

1549855:AY555 RS10695
gene id: 1549855:AY555_RS10695
uniprot id: A0A145VTA2
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1549855:AY555 RS07995
gene id: 1549855:AY555_RS07995
uniprot id: A0A143DEG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1549855:AY555 RS01970
gene id: 1549855:AY555_RS01970
uniprot id: A0A143DBP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1549855:AY555 RS04235
gene id: 1549855:AY555_RS04235
uniprot id: A0A143DEH7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1549855:AY555 RS06260
gene id: 1549855:AY555_RS06260
uniprot id: A0A143DDS4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1549855:AY555 RS02280
gene id: 1549855:AY555_RS02280
uniprot id: A0A143DBT2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1549855:AY555 RS01450
gene id: 1549855:AY555_RS01450
uniprot id: A0A143DBM4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1549855:AY555 RS00345
gene id: 1549855:AY555_RS00345
uniprot id: A0A143DC63
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1549855:AY555 RS05010
gene id: 1549855:AY555_RS05010
uniprot id: A0A143DFQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1549855:AY555 RS04355
gene id: 1549855:AY555_RS04355
uniprot id: A0A143DFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1549855:AY555 RS08735
gene id: 1549855:AY555_RS08735
uniprot id: A0A143DET0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549855:AY555 RS02320
gene id: 1549855:AY555_RS02320
uniprot id: A0A143DFG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1549855:AY555 RS11285
gene id: 1549855:AY555_RS11285
uniprot id: A0A143DGN2
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1549855:AY555 RS07625
gene id: 1549855:AY555_RS07625
uniprot id: A0A143DFT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1549855:AY555 RS00795
gene id: 1549855:AY555_RS00795
uniprot id: A0A143DH09
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS02065
gene id: 1549855:AY555_RS02065
uniprot id: A0A143DBS0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1549855:AY555 RS10900
gene id: 1549855:AY555_RS10900
uniprot id: A0A145VR67
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1549855:AY555 RS01565
gene id: 1549855:AY555_RS01565
uniprot id: A0A143DH20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1549855:AY555 RS07425
gene id: 1549855:AY555_RS07425
uniprot id: A0A143DFW4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1549855:AY555 RS04170
gene id: 1549855:AY555_RS04170
uniprot id: A0A143DD98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1549855:AY555 RS00270
gene id: 1549855:AY555_RS00270
uniprot id: A0A143DBG7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1549855:AY555 RS03085
gene id: 1549855:AY555_RS03085
uniprot id: A0A143DCE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1549855:AY555 RS05140
gene id: 1549855:AY555_RS05140
uniprot id: A0A143DD58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1549855:AY555 RS04255
gene id: 1549855:AY555_RS04255
uniprot id: A0A143DCR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1549855:AY555 RS05950
gene id: 1549855:AY555_RS05950
uniprot id: A0A143DDK0
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS00375
gene id: 1549855:AY555_RS00375
uniprot id: A0A143DCN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

1549855:AY555 RS04365
gene id: 1549855:AY555_RS04365
uniprot id: A0A143DCU2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1549855:AY555 RS02655
gene id: 1549855:AY555_RS02655
uniprot id: A0A143DCJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549855:AY555 RS05055
gene id: 1549855:AY555_RS05055
uniprot id: A0A143DDM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1549855:AY555 RS02355
gene id: 1549855:AY555_RS02355
uniprot id: A0A143DCE6
names: Subcellular Location Annotation
messages: Cell inner membrane

1549855:AY555 RS02210
gene id: 1549855:AY555_RS02210
uniprot id: A0A143DBT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

1549855:AY555 RS01645
gene id: 1549855:AY555_RS01645
uniprot id: A0A143DBQ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1549855:AY555 RS01680
gene id: 1549855:AY555_RS01680
uniprot id: A0A143DFH2
names: Similarity
messages: Belongs to the BolA/IbaG family.

1549855:AY555 RS01165
gene id: 1549855:AY555_RS01165
uniprot id: A0A143DB95
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1549855:AY555 RS05920
gene id: 1549855:AY555_RS05920
uniprot id: A0A143DET7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1549855:AY555 RS03700
gene id: 1549855:AY555_RS03700
uniprot id: A0A143DCN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1549855:AY555 RS04910
gene id: 1549855:AY555_RS04910
uniprot id: A0A143DD77
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1549855:AY555 RS05820
gene id: 1549855:AY555_RS05820
uniprot id: A0A143DDG3
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS00295
gene id: 1549855:AY555_RS00295
uniprot id: A0A143DC53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1549855:AY555 RS03455
gene id: 1549855:AY555_RS03455
uniprot id: A0A143DCD8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.

1549855:AY555 RS11185
gene id: 1549855:AY555_RS11185
uniprot id: A0A145VS53
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS04940
gene id: 1549855:AY555_RS04940
uniprot id: A0A143DDL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1549855:AY555 RS08700
gene id: 1549855:AY555_RS08700
uniprot id: A0A143DGI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549855:AY555 RS09115
gene id: 1549855:AY555_RS09115
uniprot id: A0A143DF17
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1549855:AY555 RS02260
gene id: 1549855:AY555_RS02260
uniprot id: A0A143DBV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1549855:AY555 RS04395
gene id: 1549855:AY555_RS04395
uniprot id: A0A143DE44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1549855:AY555 RS07985
gene id: 1549855:AY555_RS07985
uniprot id: A0A143DFQ8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1549855:AY555 RS01905
gene id: 1549855:AY555_RS01905
uniprot id: A0A143DCY3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1549855:AY555 RS00035
gene id: 1549855:AY555_RS00035
uniprot id: A0A143DBC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1549855:AY555 RS07475
gene id: 1549855:AY555_RS07475
uniprot id: A0A143DFY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1549855:AY555 RS07500
gene id: 1549855:AY555_RS07500
uniprot id: A0A143DE87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1549855:AY555 RS00470
gene id: 1549855:AY555_RS00470
uniprot id: A0A143DC95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1549855:AY555 RS02195
gene id: 1549855:AY555_RS02195
uniprot id: A0A143DBT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1549855:AY555 RS06790
gene id: 1549855:AY555_RS06790
uniprot id: A0A143DF86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1549855:AY555 RS10195
gene id: 1549855:AY555_RS10195
uniprot id: A0A143DGM9
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1549855:AY555 RS08870
gene id: 1549855:AY555_RS08870
uniprot id: A0A143DF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1549855:AY555 RS08485
gene id: 1549855:AY555_RS08485
uniprot id: A0A143DGG2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1549855:AY555 RS08875
gene id: 1549855:AY555_RS08875
uniprot id: A0A143DEX6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS01980
gene id: 1549855:AY555_RS01980
uniprot id: A0A143DBN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1549855:AY555 RS02445
gene id: 1549855:AY555_RS02445
uniprot id: A0A143DC44
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1549855:AY555 RS10240
gene id: 1549855:AY555_RS10240
uniprot id: A0A143DH71
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1549855:AY555 RS09655
gene id: 1549855:AY555_RS09655
uniprot id: A0A143DFR2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1549855:AY555 RS05695
gene id: 1549855:AY555_RS05695
uniprot id: A0A143DFT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1549855:AY555 RS01025
gene id: 1549855:AY555_RS01025
uniprot id: A0A143DCJ7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1549855:AY555 RS08720
gene id: 1549855:AY555_RS08720
uniprot id: A0A143DEP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549855:AY555 RS05880
gene id: 1549855:AY555_RS05880
uniprot id: A0A143DDK2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1549855:AY555 RS05580
gene id: 1549855:AY555_RS05580
uniprot id: A0A143DDI7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1549855:AY555 RS06310
gene id: 1549855:AY555_RS06310
uniprot id: A0A143DDM6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1549855:AY555 RS04770
gene id: 1549855:AY555_RS04770
uniprot id: A0A143DCZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1549855:AY555 RS02385
gene id: 1549855:AY555_RS02385
uniprot id: A0A143DC34
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1549855:AY555 RS05735
gene id: 1549855:AY555_RS05735
uniprot id: A0A143DG92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1549855:AY555 RS08000
gene id: 1549855:AY555_RS08000
uniprot id: A0A143DEN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1549855:AY555 RS00955
gene id: 1549855:AY555_RS00955
uniprot id: A0A143DBS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1549855:AY555 RS11190
gene id: 1549855:AY555_RS11190
uniprot id: A0A145VS64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1549855:AY555 RS05050
gene id: 1549855:AY555_RS05050
uniprot id: A0A143DH85
names: Similarity
messages: Belongs to the PRORSD1 family.

1549855:AY555 RS03675
gene id: 1549855:AY555_RS03675
uniprot id: A0A143DCI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1549855:AY555 RS01440
gene id: 1549855:AY555_RS01440
uniprot id: A0A143DBF4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1549855:AY555 RS00510
gene id: 1549855:AY555_RS00510
uniprot id: A0A143DB00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1549855:AY555 RS09480
gene id: 1549855:AY555_RS09480
uniprot id: A0A143DF49
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1549855:AY555 RS02635
gene id: 1549855:AY555_RS02635
uniprot id: A0A143DDQ2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1549855:AY555 RS00160
gene id: 1549855:AY555_RS00160
uniprot id: A0A143DAU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1549855:AY555 RS06130
gene id: 1549855:AY555_RS06130
uniprot id: A0A143DFF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1549855:AY555 RS05840
gene id: 1549855:AY555_RS05840
uniprot id: A0A143DF77
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1549855:AY555 RS01730
gene id: 1549855:AY555_RS01730
uniprot id: A0A143DBI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1549855:AY555 RS07785
gene id: 1549855:AY555_RS07785
uniprot id: A0A143DGG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1549855:AY555 RS05510
gene id: 1549855:AY555_RS05510
uniprot id: A0A143DDB4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1549855:AY555 RS08210
gene id: 1549855:AY555_RS08210
uniprot id: A0A143DF01
names: Similarity
messages: Belongs to the UPF0174 family.

1549855:AY555 RS04730
gene id: 1549855:AY555_RS04730
uniprot id: A0A143DD01
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1549855:AY555 RS01015
gene id: 1549855:AY555_RS01015
uniprot id: A0A143DB78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1549855:AY555 RS05365
gene id: 1549855:AY555_RS05365
uniprot id: A0A143DDM2
names: Similarity
messages: Belongs to the peptidase M16 family.

1549855:AY555 RS07350
gene id: 1549855:AY555_RS07350
uniprot id: A0A143DEL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1549855:AY555 RS01030
gene id: 1549855:AY555_RS01030
uniprot id: A0A143DBA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1549855:AY555 RS00265
gene id: 1549855:AY555_RS00265
uniprot id: A0A143DB99
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS04205
gene id: 1549855:AY555_RS04205
uniprot id: A0A143DCQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1549855:AY555 RS08585
gene id: 1549855:AY555_RS08585
uniprot id: A0A143DGH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1549855:AY555 RS04670
gene id: 1549855:AY555_RS04670
uniprot id: A0A143DCZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1549855:AY555 RS08690
gene id: 1549855:AY555_RS08690
uniprot id: A0A143DEZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS04780
gene id: 1549855:AY555_RS04780
uniprot id: A0A143DD57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1549855:AY555 RS05765
gene id: 1549855:AY555_RS05765
uniprot id: A0A143DDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1549855:AY555 RS04890
gene id: 1549855:AY555_RS04890
uniprot id: A0A143DFL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1549855:AY555 RS00680
gene id: 1549855:AY555_RS00680
uniprot id: A0A143DFD6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1549855:AY555 RS06800
gene id: 1549855:AY555_RS06800
uniprot id: A0A143DDZ6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1549855:AY555 RS01265
gene id: 1549855:AY555_RS01265
uniprot id: A0A143DBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1549855:AY555 RS04030
gene id: 1549855:AY555_RS04030
uniprot id: A0A143DD16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1549855:AY555 RS09160
gene id: 1549855:AY555_RS09160
uniprot id: A0A143DF07
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1549855:AY555 RS03345
gene id: 1549855:AY555_RS03345
uniprot id: A0A143DCC0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1549855:AY555 RS07530
gene id: 1549855:AY555_RS07530
uniprot id: A0A143DEN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS07840
gene id: 1549855:AY555_RS07840
uniprot id: A0A143DEK7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1549855:AY555 RS05345
gene id: 1549855:AY555_RS05345
uniprot id: A0A143DDE7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1549855:AY555 RS05900
gene id: 1549855:AY555_RS05900
uniprot id: A0A143DDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1549855:AY555 RS06820
gene id: 1549855:AY555_RS06820
uniprot id: A0A143DFU7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1549855:AY555 RS00075
gene id: 1549855:AY555_RS00075
uniprot id: A0A143DFB9
names: Similarity
messages: Belongs to the type III secretion exporter family.

1549855:AY555 RS08615
gene id: 1549855:AY555_RS08615
uniprot id: A0A143DER9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1549855:AY555 RS04830
gene id: 1549855:AY555_RS04830
uniprot id: A0A143DD00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1549855:AY555 RS08725
gene id: 1549855:AY555_RS08725
uniprot id: A0A143DG25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549855:AY555 RS08830
gene id: 1549855:AY555_RS08830
uniprot id: A0A143DES5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1549855:AY555 RS00410
gene id: 1549855:AY555_RS00410
uniprot id: A0A143DC78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1549855:AY555 RS06990
gene id: 1549855:AY555_RS06990
uniprot id: A0A143DGB9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1549855:AY555 RS04225
gene id: 1549855:AY555_RS04225
uniprot id: A0A143DG67
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1549855:AY555 RS07880
gene id: 1549855:AY555_RS07880
uniprot id: A0A143DEE0
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1549855:AY555 RS01955
gene id: 1549855:AY555_RS01955
uniprot id: A0A143DCZ4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1549855:AY555 RS03280
gene id: 1549855:AY555_RS03280
uniprot id: A0A143DFJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1549855:AY555 RS02265
gene id: 1549855:AY555_RS02265
uniprot id: A0A143DBU8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1549855:AY555 RS07675
gene id: 1549855:AY555_RS07675
uniprot id: A0A143DE84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1549855:AY555 RS10595
gene id: 1549855:AY555_RS10595
uniprot id: A0A143DGR7
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1549855:AY555 RS02325
gene id: 1549855:AY555_RS02325
uniprot id: A0A143DBV9
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS01515
gene id: 1549855:AY555_RS01515
uniprot id: A0A143DBF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1549855:AY555 RS05435
gene id: 1549855:AY555_RS05435
uniprot id: A0A143DDA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1549855:AY555 RS00920
gene id: 1549855:AY555_RS00920
uniprot id: A0A143DB77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1549855:AY555 RS08930
gene id: 1549855:AY555_RS08930
uniprot id: A0A143DGL5
names: Similarity
messages: Belongs to the TrpC family.

1549855:AY555 RS08730
gene id: 1549855:AY555_RS08730
uniprot id: A0A143DEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1549855:AY555 RS05960
gene id: 1549855:AY555_RS05960
uniprot id: A0A143DDX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1549855:AY555 RS07725
gene id: 1549855:AY555_RS07725
uniprot id: A0A143DE91
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS05690
gene id: 1549855:AY555_RS05690
uniprot id: A0A143DDG6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1549855:AY555 RS03715
gene id: 1549855:AY555_RS03715
uniprot id: A0A143DCW5
names: Similarity
messages: Belongs to the Tim44 family.

1549855:AY555 RS08715
gene id: 1549855:AY555_RS08715
uniprot id: A0A143DET3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549855:AY555 RS04005
gene id: 1549855:AY555_RS04005
uniprot id: A0A143DCM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1549855:AY555 RS03965
gene id: 1549855:AY555_RS03965
uniprot id: A0A143DD05
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1549855:AY555 RS07295
gene id: 1549855:AY555_RS07295
uniprot id: A0A143DE30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1549855:AY555 RS05680
gene id: 1549855:AY555_RS05680
uniprot id: A0A143DDE3
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS01745
gene id: 1549855:AY555_RS01745
uniprot id: A0A143DBL0
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1549855:AY555 RS05330
gene id: 1549855:AY555_RS05330
uniprot id: A0A143DEI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1549855:AY555 RS07195
gene id: 1549855:AY555_RS07195
uniprot id: A0A143DE45
names: Similarity
messages: Belongs to the UPF0246 family.

1549855:AY555 RS00385
gene id: 1549855:AY555_RS00385
uniprot id: A0A143DFE0
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS05895
gene id: 1549855:AY555_RS05895
uniprot id: A0A143DF89
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1549855:AY555 RS05940
gene id: 1549855:AY555_RS05940
uniprot id: A0A143DDN9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1549855:AY555 RS09285
gene id: 1549855:AY555_RS09285
uniprot id: A0A143DF45
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

1549855:AY555 RS01530
gene id: 1549855:AY555_RS01530
uniprot id: A0A143DBV2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1549855:AY555 RS07405
gene id: 1549855:AY555_RS07405
uniprot id: A0A143DEM0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1549855:AY555 RS08835
gene id: 1549855:AY555_RS08835
uniprot id: A0A143DG46
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1549855:AY555 RS00395
gene id: 1549855:AY555_RS00395
uniprot id: A0A143DBI3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1549855:AY555 RS03825
gene id: 1549855:AY555_RS03825
uniprot id: A0A143DCJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1549855:AY555 RS01315
gene id: 1549855:AY555_RS01315
uniprot id: A0A143DBD5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1549855:AY555 RS01170
gene id: 1549855:AY555_RS01170
uniprot id: A0A143DBD3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1549855:AY555 RS08290
gene id: 1549855:AY555_RS08290
uniprot id: A0A143DEK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1549855:AY555 RS04185
gene id: 1549855:AY555_RS04185
uniprot id: A0A143DE13
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

1549855:AY555 RS02215
gene id: 1549855:AY555_RS02215
uniprot id: A0A143DC04
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

1549855:AY555 RS06105
gene id: 1549855:AY555_RS06105
uniprot id: A0A143DG17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1549855:AY555 RS00090
gene id: 1549855:AY555_RS00090
uniprot id: A0A143DB66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1549855:AY555 RS11260
gene id: 1549855:AY555_RS11260
uniprot id: A0A143DGT0
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1549855:AY555 RS00655
gene id: 1549855:AY555_RS00655
uniprot id: A0A143DB24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1549855:AY555 RS01385
gene id: 1549855:AY555_RS01385
uniprot id: A0A143DBL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1549855:AY555 RS09620
gene id: 1549855:AY555_RS09620
uniprot id: A0A143DGG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1549855:AY555 RS04580
gene id: 1549855:AY555_RS04580
uniprot id: A0A143DCY0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1549855:AY555 RS07150
gene id: 1549855:AY555_RS07150
uniprot id: A0A143DE38
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1549855:AY555 RS07510
gene id: 1549855:AY555_RS07510
uniprot id: A0A143DEG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1549855:AY555 RS03480
gene id: 1549855:AY555_RS03480
uniprot id: A0A143DCF4
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1549855:AY555 RS05860
gene id: 1549855:AY555_RS05860
uniprot id: A0A143DDF0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1549855:AY555 RS11135
gene id: 1549855:AY555_RS11135
uniprot id: A0A145VS31
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1549855:AY555 RS07680
gene id: 1549855:AY555_RS07680
uniprot id: A0A143DFL3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1549855:AY555 RS05280
gene id: 1549855:AY555_RS05280
uniprot id: A0A143DD70
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1549855:AY555 RS04715
gene id: 1549855:AY555_RS04715
uniprot id: A0A143DCX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1549855:AY555 RS06085
gene id: 1549855:AY555_RS06085
uniprot id: A0A143DE74
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1549855:AY555 RS02460
gene id: 1549855:AY555_RS02460
uniprot id: A0A143DDM3
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS04665
gene id: 1549855:AY555_RS04665
uniprot id: A0A143DG78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1549855:AY555 RS03830
gene id: 1549855:AY555_RS03830
uniprot id: A0A143DEB7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1549855:AY555 RS07835
gene id: 1549855:AY555_RS07835
uniprot id: A0A143DH38
names: Cofactor
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

1549855:AY555 RS01805
gene id: 1549855:AY555_RS01805
uniprot id: A0A143DCW4
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1549855:AY555 RS05495
gene id: 1549855:AY555_RS05495
uniprot id: A0A143DDB5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549855:AY555 RS09555
gene id: 1549855:AY555_RS09555
uniprot id: A0A143DF65
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1549855:AY555 RS05350
gene id: 1549855:AY555_RS05350
uniprot id: A0A143DDA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1549855:AY555 RS01630
gene id: 1549855:AY555_RS01630
uniprot id: A0A143DCT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

1549855:AY555 RS03295
gene id: 1549855:AY555_RS03295
uniprot id: A0A143DCC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1549855:AY555 RS08790
gene id: 1549855:AY555_RS08790
uniprot id: A0A143DEV6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1549855:AY555 RS03850
gene id: 1549855:AY555_RS03850
uniprot id: A0A143DCL6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS10370
gene id: 1549855:AY555_RS10370
uniprot id: A0A143DG71
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS01125
gene id: 1549855:AY555_RS01125
uniprot id: A0A143DBH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1549855:AY555 RS01910
gene id: 1549855:AY555_RS01910
uniprot id: A0A143DBN6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1549855:AY555 RS00840
gene id: 1549855:AY555_RS00840
uniprot id: A0A143DBJ5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1549855:AY555 RS05375
gene id: 1549855:AY555_RS05375
uniprot id: A0A143DD72
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1549855:AY555 RS03160
gene id: 1549855:AY555_RS03160
uniprot id: A0A143DCL8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1549855:AY555 RS02420
gene id: 1549855:AY555_RS02420
uniprot id: A0A143DBV4
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS06880
gene id: 1549855:AY555_RS06880
uniprot id: A0A143DEK2
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS05225
gene id: 1549855:AY555_RS05225
uniprot id: A0A143DDC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1549855:AY555 RS08540
gene id: 1549855:AY555_RS08540
uniprot id: A0A143DEQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1549855:AY555 RS02775
gene id: 1549855:AY555_RS02775
uniprot id: A0A143DC37
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1549855:AY555 RS05980
gene id: 1549855:AY555_RS05980
uniprot id: A0A143DDH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1549855:AY555 RS04995
gene id: 1549855:AY555_RS04995
uniprot id: A0A143DDM0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1549855:AY555 RS07830
gene id: 1549855:AY555_RS07830
uniprot id: A0A143DED6
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1549855:AY555 RS08035
gene id: 1549855:AY555_RS08035
uniprot id: A0A143DFR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1549855:AY555 RS08945
gene id: 1549855:AY555_RS08945
uniprot id: A0A143DEW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549855:AY555 RS03460
gene id: 1549855:AY555_RS03460
uniprot id: A0A143DE51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1549855:AY555 RS11415
gene id: 1549855:AY555_RS11415
uniprot id: A0A143DG61
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1549855:AY555 RS04390
gene id: 1549855:AY555_RS04390
uniprot id: A0A143DCT6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1549855:AY555 RS03970
gene id: 1549855:AY555_RS03970
uniprot id: A0A143DD66
names: Similarity
messages: Belongs to the ros/MucR family.

1549855:AY555 RS06300
gene id: 1549855:AY555_RS06300
uniprot id: A0A143DEA1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1549855:AY555 RS03705
gene id: 1549855:AY555_RS03705
uniprot id: A0A143DCH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1549855:AY555 RS07820
gene id: 1549855:AY555_RS07820
uniprot id: A0A143DFN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1549855:AY555 RS02520
gene id: 1549855:AY555_RS02520
uniprot id: A0A143DC56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1549855:AY555 RS10235
gene id: 1549855:AY555_RS10235
uniprot id: A0A143DG99
names: Similarity
messages: Belongs to the RelE toxin family.

1549855:AY555 RS05210
gene id: 1549855:AY555_RS05210
uniprot id: A0A143DFQ5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1549855:AY555 RS04970
gene id: 1549855:AY555_RS04970
uniprot id: A0A143DD87
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1549855:AY555 RS03250
gene id: 1549855:AY555_RS03250
uniprot id: A0A143DCA8
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS06140
gene id: 1549855:AY555_RS06140
uniprot id: A0A143DE85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1549855:AY555 RS00905
gene id: 1549855:AY555_RS00905
uniprot id: A0A143DB58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1549855:AY555 RS08520
gene id: 1549855:AY555_RS08520
uniprot id: A0A143DGI3
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1549855:AY555 RS03680
gene id: 1549855:AY555_RS03680
uniprot id: A0A143DFI6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1549855:AY555 RS09215
gene id: 1549855:AY555_RS09215
uniprot id: A0A143DF15
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1549855:AY555 RS07775
gene id: 1549855:AY555_RS07775
uniprot id: A0A143DHG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1549855:AY555 RS00845
gene id: 1549855:AY555_RS00845
uniprot id: A0A143DBQ6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1549855:AY555 RS04895
gene id: 1549855:AY555_RS04895
uniprot id: A0A143DD12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1549855:AY555 RS03175
gene id: 1549855:AY555_RS03175
uniprot id: A0A143DCA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1549855:AY555 RS03855
gene id: 1549855:AY555_RS03855
uniprot id: A0A143DDW5
names: Similarity
messages: Belongs to the ArsC family.

1549855:AY555 RS01925
gene id: 1549855:AY555_RS01925
uniprot id: A0A143DBM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1549855:AY555 RS07645
gene id: 1549855:AY555_RS07645
uniprot id: A0A143DEC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1549855:AY555 RS00050
gene id: 1549855:AY555_RS00050
uniprot id: A0A143DAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

1549855:AY555 RS03340
gene id: 1549855:AY555_RS03340
uniprot id: A0A143DCW8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1549855:AY555 RS02040
gene id: 1549855:AY555_RS02040
uniprot id: A0A143DBN9
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS01990
gene id: 1549855:AY555_RS01990
uniprot id: A0A143DC31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1549855:AY555 RS04605
gene id: 1549855:AY555_RS04605
uniprot id: A0A143DCY1
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1549855:AY555 RS00675
gene id: 1549855:AY555_RS00675
uniprot id: A0A143DB25
names: Similarity
messages: Belongs to the peptidase S11 family.

1549855:AY555 RS04610
gene id: 1549855:AY555_RS04610
uniprot id: A0A143DG63
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS01570
gene id: 1549855:AY555_RS01570
uniprot id: A0A143DBH6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1549855:AY555 RS03125
gene id: 1549855:AY555_RS03125
uniprot id: A0A143DDJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1549855:AY555 RS06500
gene id: 1549855:AY555_RS06500
uniprot id: A0A143DF40
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1549855:AY555 RS03285
gene id: 1549855:AY555_RS03285
uniprot id: A0A143DCV9
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1549855:AY555 RS00980
gene id: 1549855:AY555_RS00980
uniprot id: A0A143DB79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1549855:AY555 RS03695
gene id: 1549855:AY555_RS03695
uniprot id: A0A143DCJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1549855:AY555 RS00870
gene id: 1549855:AY555_RS00870
uniprot id: A0A143DB57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1549855:AY555 RS09120
gene id: 1549855:AY555_RS09120
uniprot id: A0A143DGP3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1549855:AY555 RS00805
gene id: 1549855:AY555_RS00805
uniprot id: A0A143DB76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

1549855:AY555 RS08665
gene id: 1549855:AY555_RS08665
uniprot id: A0A143DES2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1549855:AY555 RS03915
gene id: 1549855:AY555_RS03915
uniprot id: A0A143DCZ5
names: Similarity
messages: Belongs to the glutamate synthase family.

1549855:AY555 RS05710
gene id: 1549855:AY555_RS05710
uniprot id: A0A143DDG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1549855:AY555 RS07950
gene id: 1549855:AY555_RS07950
uniprot id: A0A143DEM3
names: Similarity
messages: Belongs to the DEAD box helicase family.

1549855:AY555 RS08065
gene id: 1549855:AY555_RS08065
uniprot id: A0A143DEJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1549855:AY555 RS03925
gene id: 1549855:AY555_RS03925
uniprot id: A0A143DCK2
names: Similarity
messages: Belongs to the thioredoxin family.

1549855:AY555 RS09400
gene id: 1549855:AY555_RS09400
uniprot id: A0A143DGT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1549855:AY555 RS03205
gene id: 1549855:AY555_RS03205
uniprot id: A0A143DE09
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

1549855:AY555 RS04305
gene id: 1549855:AY555_RS04305
uniprot id: A0A143DD61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1549855:AY555 RS03990
gene id: 1549855:AY555_RS03990
uniprot id: A0A143DDY5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1549855:AY555 RS02475
gene id: 1549855:AY555_RS02475
uniprot id: A0A143DFS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1549855:AY555 RS04295
gene id: 1549855:AY555_RS04295
uniprot id: A0A143DCT0
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS10950
gene id: 1549855:AY555_RS10950
uniprot id: A0A145VRC4
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1549855:AY555 RS07855
gene id: 1549855:AY555_RS07855
uniprot id: A0A143DEU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1549855:AY555 RS01930
gene id: 1549855:AY555_RS01930
uniprot id: A0A143DDE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1549855:AY555 RS09030
gene id: 1549855:AY555_RS09030
uniprot id: A0A143DF56
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1549855:AY555 RS03035
gene id: 1549855:AY555_RS03035
uniprot id: A0A143DDX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1549855:AY555 RS09305
gene id: 1549855:AY555_RS09305
uniprot id: A0A143DF26
names: Similarity
messages: Belongs to the transketolase family.

1549855:AY555 RS00860
gene id: 1549855:AY555_RS00860
uniprot id: A0A143DCG9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1549855:AY555 RS03805
gene id: 1549855:AY555_RS03805
uniprot id: A0A143DDV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1549855:AY555 RS08705
gene id: 1549855:AY555_RS08705
uniprot id: A0A143DF78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1549855:AY555 RS00865
gene id: 1549855:AY555_RS00865
uniprot id: A0A143DB69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1549855:AY555 RS04495
gene id: 1549855:AY555_RS04495
uniprot id: A0A143DCT1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1549855:AY555 RS09240
gene id: 1549855:AY555_RS09240
uniprot id: A0A143DFI4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1549855:AY555 RS01815
gene id: 1549855:AY555_RS01815
uniprot id: A0A143DBL7
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS01020
gene id: 1549855:AY555_RS01020
uniprot id: A0A143DBB3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1549855:AY555 RS06115
gene id: 1549855:AY555_RS06115
uniprot id: A0A143DDQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1549855:AY555 RS10350
gene id: 1549855:AY555_RS10350
uniprot id: A0A143DC71
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1549855:AY555 RS05445
gene id: 1549855:AY555_RS05445
uniprot id: A0A143DEK5
names: Similarity
messages: Belongs to the YggT family.

1549855:AY555 RS07770
gene id: 1549855:AY555_RS07770
uniprot id: A0A143DFZ6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS00140
gene id: 1549855:AY555_RS00140
uniprot id: A0A143DAU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1549855:AY555 RS08865
gene id: 1549855:AY555_RS08865
uniprot id: A0A143DEU9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1549855:AY555 RS04660
gene id: 1549855:AY555_RS04660
uniprot id: A0A143DCW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1549855:AY555 RS05295
gene id: 1549855:AY555_RS05295
uniprot id: A0A143DD91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1549855:AY555 RS08935
gene id: 1549855:AY555_RS08935
uniprot id: A0A143DFB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1549855:AY555 RS07520
gene id: 1549855:AY555_RS07520
uniprot id: A0A143DE98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Membrane
messages: Periplasm

1549855:AY555 RS06655
gene id: 1549855:AY555_RS06655
uniprot id: A0A143DDT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1549855:AY555 RS06165
gene id: 1549855:AY555_RS06165
uniprot id: A0A143DDN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1549855:AY555 RS03120
gene id: 1549855:AY555_RS03120
uniprot id: A0A143DC98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1549855:AY555 RS03540
gene id: 1549855:AY555_RS03540
uniprot id: A0A143DCG7
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1549855:AY555 RS10455
gene id: 1549855:AY555_RS10455
uniprot id: A0A143DGD8
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS08350
gene id: 1549855:AY555_RS08350
uniprot id: A0A143DEI9
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS10360
gene id: 1549855:AY555_RS10360
uniprot id: A0A143DG96
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS00150
gene id: 1549855:AY555_RS00150
uniprot id: A0A143DB80
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1549855:AY555 RS10405
gene id: 1549855:AY555_RS10405
uniprot id: A0A143DGC8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1549855:AY555 RS11090
gene id: 1549855:AY555_RS11090
uniprot id: A0A143DHW3
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1549855:AY555 RS06985
gene id: 1549855:AY555_RS06985
uniprot id: A0A143DHD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1549855:AY555 RS08020
gene id: 1549855:AY555_RS08020
uniprot id: A0A143DF24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1549855:AY555 RS01560
gene id: 1549855:AY555_RS01560
uniprot id: A0A143DCS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1549855:AY555 RS07560
gene id: 1549855:AY555_RS07560
uniprot id: A0A143DFJ3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1549855:AY555 RS08510
gene id: 1549855:AY555_RS08510
uniprot id: A0A143DEW2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1549855:AY555 RS04160
gene id: 1549855:AY555_RS04160
uniprot id: A0A143DFM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1549855:AY555 RS02105
gene id: 1549855:AY555_RS02105
uniprot id: A0A143DCB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1549855:AY555 RS07315
gene id: 1549855:AY555_RS07315
uniprot id: A0A143DE63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1549855:AY555 RS11240
gene id: 1549855:AY555_RS11240
uniprot id: A0A143DH18
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS00145
gene id: 1549855:AY555_RS00145
uniprot id: A0A143DCJ8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1549855:AY555 RS05135
gene id: 1549855:AY555_RS05135
uniprot id: A0A143DD30
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1549855:AY555 RS07515
gene id: 1549855:AY555_RS07515
uniprot id: A0A143DHF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1549855:AY555 RS07280
gene id: 1549855:AY555_RS07280
uniprot id: A0A143DGC9
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

1549855:AY555 RS04340
gene id: 1549855:AY555_RS04340
uniprot id: A0A143DGV6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1549855:AY555 RS09295
gene id: 1549855:AY555_RS09295
uniprot id: A0A143DFJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS09150
gene id: 1549855:AY555_RS09150
uniprot id: A0A143DG94
names: Similarity
messages: Belongs to the asparaginase 1 family.

1549855:AY555 RS01830
gene id: 1549855:AY555_RS01830
uniprot id: A0A143DDC0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1549855:AY555 RS09055
gene id: 1549855:AY555_RS09055
uniprot id: A0A143DG20
names: Similarity
messages: Belongs to the pyruvate kinase family.

1549855:AY555 RS06860
gene id: 1549855:AY555_RS06860
uniprot id: A0A143DE57
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1549855:AY555 RS08590
gene id: 1549855:AY555_RS08590
uniprot id: A0A143DF59
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1549855:AY555 RS07045
gene id: 1549855:AY555_RS07045
uniprot id: A0A143DH16
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS07765
gene id: 1549855:AY555_RS07765
uniprot id: A0A143DG56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1549855:AY555 RS08070
gene id: 1549855:AY555_RS08070
uniprot id: A0A143DG77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1549855:AY555 RS10365
gene id: 1549855:AY555_RS10365
uniprot id: A0A143DHE9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1549855:AY555 RS03470
gene id: 1549855:AY555_RS03470
uniprot id: A0A143DCY7
names: Similarity
messages: Belongs to the peptidase S41A family.

1549855:AY555 RS08030
gene id: 1549855:AY555_RS08030
uniprot id: A0A143DEE2
names: Similarity
messages: Belongs to the MotB family.

1549855:AY555 RS07170
gene id: 1549855:AY555_RS07170
uniprot id: A0A143DEI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1549855:AY555 RS09325
gene id: 1549855:AY555_RS09325
uniprot id: A0A143DF31
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1549855:AY555 RS05110
gene id: 1549855:AY555_RS05110
uniprot id: A0A143DEV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1549855:AY555 RS11345
gene id: 1549855:AY555_RS11345
uniprot id: A0A143DG99
names: Similarity
messages: Belongs to the RelE toxin family.

1549855:AY555 RS06135
gene id: 1549855:AY555_RS06135
uniprot id: A0A143DE24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1549855:AY555 RS01005
gene id: 1549855:AY555_RS01005
uniprot id: A0A143DBT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1549855:AY555 RS08095
gene id: 1549855:AY555_RS08095
uniprot id: A0A143DEF1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1549855:AY555 RS09270
gene id: 1549855:AY555_RS09270
uniprot id: A0A143DF25
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1549855:AY555 RS05850
gene id: 1549855:AY555_RS05850
uniprot id: A0A143DDV5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1549855:AY555 RS08880
gene id: 1549855:AY555_RS08880
uniprot id: A0A143DGK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1549855:AY555 RS05605
gene id: 1549855:AY555_RS05605
uniprot id: A0A143DDB2
names: Subcellular Location Annotation
messages: Virion

1549855:AY555 RS09670
gene id: 1549855:AY555_RS09670
uniprot id: A0A143DF92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1549855:AY555 RS08010
gene id: 1549855:AY555_RS08010
uniprot id: A0A143DG93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1549855:AY555 RS07330
gene id: 1549855:AY555_RS07330
uniprot id: A0A143DEC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1549855:AY555 RS00195
gene id: 1549855:AY555_RS00195
uniprot id: A0A143DAV1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1549855:AY555 RS02345
gene id: 1549855:AY555_RS02345
uniprot id: A0A143DDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1549855:AY555 RS05190
gene id: 1549855:AY555_RS05190
uniprot id: A0A143DFL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1549855:AY555 RS01460
gene id: 1549855:AY555_RS01460
uniprot id: A0A143DD64
names: Similarity
messages: Belongs to the LOG family.

1549855:AY555 RS03615
gene id: 1549855:AY555_RS03615
uniprot id: A0A143DDS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1549855:AY555 RS06235
gene id: 1549855:AY555_RS06235
uniprot id: A0A143DDP0
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1549855:AY555 RS07430
gene id: 1549855:AY555_RS07430
uniprot id: A0A143DE50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1549855:AY555 RS07700
gene id: 1549855:AY555_RS07700
uniprot id: A0A143DED4
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS10555
gene id: 1549855:AY555_RS10555
uniprot id: A0A143DHX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1549855:AY555 RS01295
gene id: 1549855:AY555_RS01295
uniprot id: A0A143DBX5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1549855:AY555 RS08950
gene id: 1549855:AY555_RS08950
uniprot id: A0A143DEU5
names: Similarity
messages: Belongs to the citrate synthase family.

1549855:AY555 RS00985
gene id: 1549855:AY555_RS00985
uniprot id: A0A143DBG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1549855:AY555 RS05815
gene id: 1549855:AY555_RS05815
uniprot id: A0A143DFQ2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1549855:AY555 RS07955
gene id: 1549855:AY555_RS07955
uniprot id: A0A143DEH5
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1549855:AY555 RS08525
gene id: 1549855:AY555_RS08525
uniprot id: A0A143DGG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1549855:AY555 RS04000
gene id: 1549855:AY555_RS04000
uniprot id: A0A143DG43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1549855:AY555 RS04120
gene id: 1549855:AY555_RS04120
uniprot id: A0A143DCQ0
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1549855:AY555 RS08160
gene id: 1549855:AY555_RS08160
uniprot id: A0A143DEG3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1549855:AY555 RS06795
gene id: 1549855:AY555_RS06795
uniprot id: A0A143DDX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1549855:AY555 RS05855
gene id: 1549855:AY555_RS05855
uniprot id: A0A143DE17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1549855:AY555 RS04300
gene id: 1549855:AY555_RS04300
uniprot id: A0A143DEI6
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS03300
gene id: 1549855:AY555_RS03300
uniprot id: A0A143DDL7
names: Similarity
messages: Belongs to the UPF0434 family.

1549855:AY555 RS06700
gene id: 1549855:AY555_RS06700
uniprot id: A0A143DDW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1549855:AY555 RS02300
gene id: 1549855:AY555_RS02300
uniprot id: A0A143DCE0
names: Similarity
messages: Belongs to the peptidase M16 family.

1549855:AY555 RS05065
gene id: 1549855:AY555_RS05065
uniprot id: A0A143DD48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1549855:AY555 RS11165
gene id: 1549855:AY555_RS11165
uniprot id: A0A145VTI1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1549855:AY555 RS05825
gene id: 1549855:AY555_RS05825
uniprot id: A0A143DDJ2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1549855:AY555 RS00800
gene id: 1549855:AY555_RS00800
uniprot id: A0A143DB42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1549855:AY555 RS01040
gene id: 1549855:AY555_RS01040
uniprot id: A0A143DB92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1549855:AY555 RS11215
gene id: 1549855:AY555_RS11215
uniprot id: A0A143DI48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1549855:AY555 RS03165
gene id: 1549855:AY555_RS03165
uniprot id: A0A143DCT5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1549855:AY555 RS03220
gene id: 1549855:AY555_RS03220
uniprot id: A0A143DCA4
names: Similarity
messages: Belongs to the YciI family.

1549855:AY555 RS02660
gene id: 1549855:AY555_RS02660
uniprot id: A0A143DBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1549855:AY555 RS04435
gene id: 1549855:AY555_RS04435
uniprot id: A0A143DDD7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1549855:AY555 RS03815
gene id: 1549855:AY555_RS03815
uniprot id: A0A143DCK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1549855:AY555 RS04430
gene id: 1549855:AY555_RS04430
uniprot id: A0A143DD82
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1549855:AY555 RS07790
gene id: 1549855:AY555_RS07790
uniprot id: A0A143DET2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS08075
gene id: 1549855:AY555_RS08075
uniprot id: A0A143DGA3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1549855:AY555 RS08310
gene id: 1549855:AY555_RS08310
uniprot id: A0A143DEL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1549855:AY555 RS06620
gene id: 1549855:AY555_RS06620
uniprot id: A0A143DGB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS00135
gene id: 1549855:AY555_RS00135
uniprot id: A0A143DB23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1549855:AY555 RS04775
gene id: 1549855:AY555_RS04775
uniprot id: A0A143DD18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1549855:AY555 RS00520
gene id: 1549855:AY555_RS00520
uniprot id: A0A143DCA2
names: Similarity
messages: Belongs to the YicC/YloC family.

1549855:AY555 RS05095
gene id: 1549855:AY555_RS05095
uniprot id: A0A143DDA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1549855:AY555 RS03130
gene id: 1549855:AY555_RS03130
uniprot id: A0A143DC88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1549855:AY555 RS00930
gene id: 1549855:AY555_RS00930
uniprot id: A0A143DB67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1549855:AY555 RS05335
gene id: 1549855:AY555_RS05335
uniprot id: A0A143DD83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1549855:AY555 RS07585
gene id: 1549855:AY555_RS07585
uniprot id: A0A143DEB5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1549855:AY555 RS08800
gene id: 1549855:AY555_RS08800
uniprot id: A0A143DF11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1549855:AY555 RS10390
gene id: 1549855:AY555_RS10390
uniprot id: A0A143DHU4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1549855:AY555 RS04900
gene id: 1549855:AY555_RS04900
uniprot id: A0A143DD37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1549855:AY555 RS01285
gene id: 1549855:AY555_RS01285
uniprot id: A0A143DD36
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1549855:AY555 RS08825
gene id: 1549855:AY555_RS08825
uniprot id: A0A143DEV2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1549855:AY555 RS06100
gene id: 1549855:AY555_RS06100
uniprot id: A0A143DEY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

1549855:AY555 RS04245
gene id: 1549855:AY555_RS04245
uniprot id: A0A143DDA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1549855:AY555 RS04135
gene id: 1549855:AY555_RS04135
uniprot id: A0A143DCR8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS08660
gene id: 1549855:AY555_RS08660
uniprot id: A0A143DH55
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1549855:AY555 RS08710
gene id: 1549855:AY555_RS08710
uniprot id: A0A143DFE2
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1549855:AY555 RS02130
gene id: 1549855:AY555_RS02130
uniprot id: A0A143DBS8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1549855:AY555 RS03670
gene id: 1549855:AY555_RS03670
uniprot id: A0A143DCG6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1549855:AY555 RS00460
gene id: 1549855:AY555_RS00460
uniprot id: A0A143DAY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1549855:AY555 RS06075
gene id: 1549855:AY555_RS06075
uniprot id: A0A143DFD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1549855:AY555 RS07365
gene id: 1549855:AY555_RS07365
uniprot id: A0A143DE43
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1549855:AY555 RS08600
gene id: 1549855:AY555_RS08600
uniprot id: A0A143DER3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1549855:AY555 RS06375
gene id: 1549855:AY555_RS06375
uniprot id: A0A143DE53
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS01655
gene id: 1549855:AY555_RS01655
uniprot id: A0A143DD89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1549855:AY555 RS07185
gene id: 1549855:AY555_RS07185
uniprot id: A0A143DE15
names: Similarity
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.

1549855:AY555 RS06315
gene id: 1549855:AY555_RS06315
uniprot id: A0A143DDP6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1549855:AY555 RS08370
gene id: 1549855:AY555_RS08370
uniprot id: A0A143DEN1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1549855:AY555 RS09300
gene id: 1549855:AY555_RS09300
uniprot id: A0A143DFN1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1549855:AY555 RS11180
gene id: 1549855:AY555_RS11180
uniprot id: A0A145VS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1549855:AY555 RS05080
gene id: 1549855:AY555_RS05080
uniprot id: A0A143DG72
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1549855:AY555 RS02960
gene id: 1549855:AY555_RS02960
uniprot id: A0A143DCC9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1549855:AY555 RS01290
gene id: 1549855:AY555_RS01290
uniprot id: A0A143DBR1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS02005
gene id: 1549855:AY555_RS02005
uniprot id: A0A143DC94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1549855:AY555 RS00945
gene id: 1549855:AY555_RS00945
uniprot id: A0A143DCY4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1549855:AY555 RS07470
gene id: 1549855:AY555_RS07470
uniprot id: A0A143DEM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1549855:AY555 RS07105
gene id: 1549855:AY555_RS07105
uniprot id: A0A143DEN2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1549855:AY555 RS08340
gene id: 1549855:AY555_RS08340
uniprot id: A0A143DEL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1549855:AY555 RS02220
gene id: 1549855:AY555_RS02220
uniprot id: A0A143DBS1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1549855:AY555 RS06980
gene id: 1549855:AY555_RS06980
uniprot id: A0A143DFB1
names: Similarity
messages: Belongs to the hyi family.

1549855:AY555 RS09465
gene id: 1549855:AY555_RS09465
uniprot id: A0A143DFQ6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1549855:AY555 RS08975
gene id: 1549855:AY555_RS08975
uniprot id: A0A143DEZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1549855:AY555 RS08850
gene id: 1549855:AY555_RS08850
uniprot id: A0A143DFW0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1549855:AY555 RS08225
gene id: 1549855:AY555_RS08225
uniprot id: A0A143DEJ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1549855:AY555 RS05555
gene id: 1549855:AY555_RS05555
uniprot id: A0A143DEM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1549855:AY555 RS09145
gene id: 1549855:AY555_RS09145
uniprot id: A0A143DEX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1549855:AY555 RS05000
gene id: 1549855:AY555_RS05000
uniprot id: A0A143DD09
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1549855:AY555 RS04380
gene id: 1549855:AY555_RS04380
uniprot id: A0A143DDC8
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1549855:AY555 RS06735
gene id: 1549855:AY555_RS06735
uniprot id: A0A143DDV2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS04325
gene id: 1549855:AY555_RS04325
uniprot id: A0A143DE34
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549855:AY555 RS07030
gene id: 1549855:AY555_RS07030
uniprot id: A0A143DFU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

1549855:AY555 RS10640
gene id: 1549855:AY555_RS10640
uniprot id: A0A143DGI0
names: Similarity
messages: In the C-terminal section; belongs to the NRP synthetase family.

1549855:AY555 RS01785
gene id: 1549855:AY555_RS01785
uniprot id: A0A143DBY9
names: Similarity
messages: Belongs to the TrpF family.

1549855:AY555 RS01415
gene id: 1549855:AY555_RS01415
uniprot id: A0A143DFG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

1549855:AY555 RS01340
gene id: 1549855:AY555_RS01340
uniprot id: A0A143DBC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1549855:AY555 RS08280
gene id: 1549855:AY555_RS08280
uniprot id: A0A143DF12
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1549855:AY555 RS07705
gene id: 1549855:AY555_RS07705
uniprot id: A0A143DG44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1549855:AY555 RS09945
gene id: 1549855:AY555_RS09945
uniprot id: A0A143DFD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1549855:AY555 RS09455
gene id: 1549855:AY555_RS09455
uniprot id: A0A143DGU2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1549855:AY555 RS07640
gene id: 1549855:AY555_RS07640
uniprot id: A0A143DEH9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1549855:AY555 RS07160
gene id: 1549855:AY555_RS07160
uniprot id: A0A143DG49
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1549855:AY555 RS08970
gene id: 1549855:AY555_RS08970
uniprot id: A0A143DF43
names: Similarity
messages: Belongs to the peptidase S13 family.

1549855:AY555 RS03760
gene id: 1549855:AY555_RS03760
uniprot id: A0A143DFV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1549855:AY555 RS08150
gene id: 1549855:AY555_RS08150
uniprot id: A0A143DHH2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1549855:AY555 RS00970
gene id: 1549855:AY555_RS00970
uniprot id: A0A143DCI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1549855:AY555 RS00750
gene id: 1549855:AY555_RS00750
uniprot id: A0A143DB54
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1549855:AY555 RS04210
gene id: 1549855:AY555_RS04210
uniprot id: A0A143DCS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1549855:AY555 RS06805
gene id: 1549855:AY555_RS06805
uniprot id: A0A143DE48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1549855:AY555 RS09335
gene id: 1549855:AY555_RS09335
uniprot id: A0A143DF53
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1549855:AY555 RS01510
gene id: 1549855:AY555_RS01510
uniprot id: A0A143DFE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1549855:AY555 RS01625
gene id: 1549855:AY555_RS01625
uniprot id: A0A143DBJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS01250
gene id: 1549855:AY555_RS01250
uniprot id: A0A143DBE3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1549855:AY555 RS05060
gene id: 1549855:AY555_RS05060
uniprot id: A0A143DD21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1549855:AY555 RS01380
gene id: 1549855:AY555_RS01380
uniprot id: A0A143DBE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1549855:AY555 RS08515
gene id: 1549855:AY555_RS08515
uniprot id: A0A143DER6
names: Similarity
messages: Belongs to the HesB/IscA family.

1549855:AY555 RS01135
gene id: 1549855:AY555_RS01135
uniprot id: A0A143DFN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

1549855:AY555 RS01705
gene id: 1549855:AY555_RS01705
uniprot id: A0A143DBI4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1549855:AY555 RS04400
gene id: 1549855:AY555_RS04400
uniprot id: A0A143DFQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1549855:AY555 RS02555
gene id: 1549855:AY555_RS02555
uniprot id: A0A143DD92
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1549855:AY555 RS04935
gene id: 1549855:AY555_RS04935
uniprot id: A0A143DDG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1549855:AY555 RS02575
gene id: 1549855:AY555_RS02575
uniprot id: A0A143DBX7
names: Similarity
messages: Belongs to the asparagine synthetase family.

1549855:AY555 RS01800
gene id: 1549855:AY555_RS01800
uniprot id: A0A143DBM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1549855:AY555 RS12290
gene id: 1549855:AY555_RS12290
uniprot id: A0A143DHS5
names: Subcellular Location Annotation
messages: Secreted

1549855:AY555 RS04840
gene id: 1549855:AY555_RS04840
uniprot id: A0A143DD67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1549855:AY555 RS08765
gene id: 1549855:AY555_RS08765
uniprot id: A0A143DEU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1549855:AY555 RS03575
gene id: 1549855:AY555_RS03575
uniprot id: A0A143DH51
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS01300
gene id: 1549855:AY555_RS01300
uniprot id: A0A143DBB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1549855:AY555 RS01825
gene id: 1549855:AY555_RS01825
uniprot id: A0A143DBK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1549855:AY555 RS03430
gene id: 1549855:AY555_RS03430
uniprot id: A0A143DCE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1549855:AY555 RS06835
gene id: 1549855:AY555_RS06835
uniprot id: A0A143DDW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1549855:AY555 RS11830
gene id: 1549855:AY555_RS11830
uniprot id: A0A143DGS3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1549855:AY555 RS00350
gene id: 1549855:AY555_RS00350
uniprot id: A0A143DAY7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1549855:AY555 RS01390
gene id: 1549855:AY555_RS01390
uniprot id: A0A143DBD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1549855:AY555 RS02565
gene id: 1549855:AY555_RS02565
uniprot id: A0A143DBZ8
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1549855:AY555 RS07485
gene id: 1549855:AY555_RS07485
uniprot id: A0A143DE62
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1549855:AY555 RS00820
gene id: 1549855:AY555_RS00820
uniprot id: A0A143DB49
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1549855:AY555 RS09730
gene id: 1549855:AY555_RS09730
uniprot id: A0A143DGL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1549855:AY555 RS00400
gene id: 1549855:AY555_RS00400
uniprot id: A0A143DAX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1549855:AY555 RS09800
gene id: 1549855:AY555_RS09800
uniprot id: A0A143DFT3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS08635
gene id: 1549855:AY555_RS08635
uniprot id: A0A143DGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1549855:AY555 RS04810
gene id: 1549855:AY555_RS04810
uniprot id: A0A143DCY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1549855:AY555 RS03645
gene id: 1549855:AY555_RS03645
uniprot id: A0A143DFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1549855:AY555 RS09545
gene id: 1549855:AY555_RS09545
uniprot id: A0A143DF58
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1549855:AY555 RS10940
gene id: 1549855:AY555_RS10940
uniprot id: A0A145VRA1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1549855:AY555 RS04015
gene id: 1549855:AY555_RS04015
uniprot id: A0A143DCT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1549855:AY555 RS08740
gene id: 1549855:AY555_RS08740
uniprot id: A0A143DF02
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1549855:AY555 RS02630
gene id: 1549855:AY555_RS02630
uniprot id: A0A143DBY8
names: Similarity
messages: Belongs to the asparagine synthetase family.

1549855:AY555 RS00105
gene id: 1549855:AY555_RS00105
uniprot id: A0A143DAW3
names: Similarity
messages: Belongs to the MotB family.

1549855:AY555 RS03785
gene id: 1549855:AY555_RS03785
uniprot id: A0A143DD34
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1549855:AY555 RS09165
gene id: 1549855:AY555_RS09165
uniprot id: A0A143DG19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1549855:AY555 RS01240
gene id: 1549855:AY555_RS01240
uniprot id: A0A143DBW5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1549855:AY555 RS00235
gene id: 1549855:AY555_RS00235
uniprot id: A0A143DAX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1549855:AY555 RS11000
gene id: 1549855:AY555_RS11000
uniprot id: A0A145VRK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1549855:AY555 RS07355
gene id: 1549855:AY555_RS07355
uniprot id: A0A143DER8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS07875
gene id: 1549855:AY555_RS07875
uniprot id: A0A143DEF3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1549855:AY555 RS10580
gene id: 1549855:AY555_RS10580
uniprot id: A0A143DHL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1549855:AY555 RS07300
gene id: 1549855:AY555_RS07300
uniprot id: A0A143DE31
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1549855:AY555 RS09795
gene id: 1549855:AY555_RS09795
uniprot id: A0A143DGY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1549855:AY555 RS07540
gene id: 1549855:AY555_RS07540
uniprot id: A0A143DEU6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1549855:AY555 RS00975
gene id: 1549855:AY555_RS00975
uniprot id: A0A143DB92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1549855:AY555 RS10785
gene id: 1549855:AY555_RS10785
uniprot id: A0A145VQP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1549855:AY555 RS09275
gene id: 1549855:AY555_RS09275
uniprot id: A0A143DF19
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1549855:AY555 RS03755
gene id: 1549855:AY555_RS03755
uniprot id: A0A143DCP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1549855:AY555 RS05845
gene id: 1549855:AY555_RS05845
uniprot id: A0A143DGZ2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1549855:AY555 RS00890
gene id: 1549855:AY555_RS00890
uniprot id: A0A143DCX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1549855:AY555 RS09135
gene id: 1549855:AY555_RS09135
uniprot id: A0A143DFJ8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1549855:AY555 RS06785
gene id: 1549855:AY555_RS06785
uniprot id: A0A143DDW2
names: Similarity
messages: Belongs to the TlyA family.

1549855:AY555 RS07615
gene id: 1549855:AY555_RS07615
uniprot id: A0A143DE76
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1549855:AY555 RS07015
gene id: 1549855:AY555_RS07015
uniprot id: A0A143DE19
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1549855:AY555 RS08460
gene id: 1549855:AY555_RS08460
uniprot id: A0A143DGF5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1549855:AY555 RS07490
gene id: 1549855:AY555_RS07490
uniprot id: A0A143DE61
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1549855:AY555 RS04060
gene id: 1549855:AY555_RS04060
uniprot id: A0A143DCN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1549855:AY555 RS05430
gene id: 1549855:AY555_RS05430
uniprot id: A0A143DD80
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1549855:AY555 RS07320
gene id: 1549855:AY555_RS07320
uniprot id: A0A143DE64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1549855:AY555 RS04870
gene id: 1549855:AY555_RS04870
uniprot id: A0A143DDK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1549855:AY555 RS00885
gene id: 1549855:AY555_RS00885
uniprot id: A0A143DB61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1549855:AY555 RS00880
gene id: 1549855:AY555_RS00880
uniprot id: A0A143DBD8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1549855:AY555 RS00895
gene id: 1549855:AY555_RS00895
uniprot id: A0A143DBK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1549855:AY555 RS00650
gene id: 1549855:AY555_RS00650
uniprot id: A0A143DB98
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1549855:AY555 RS01010
gene id: 1549855:AY555_RS01010
uniprot id: A0A143DFE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1549855:AY555 RS09280
gene id: 1549855:AY555_RS09280
uniprot id: A0A143DFA1
names: Similarity
messages: Belongs to the universal stress protein A family.

1549855:AY555 RS09410
gene id: 1549855:AY555_RS09410
uniprot id: A0A143DFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1549855:AY555 RS06125
gene id: 1549855:AY555_RS06125
uniprot id: A0A143DDP3
names: Subcellular Location Annotation
messages: Membrane

1549855:AY555 RS05835
gene id: 1549855:AY555_RS05835
uniprot id: A0A143DDI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

1549855:AY555 RS05230
gene id: 1549855:AY555_RS05230
uniprot id: A0A143DFZ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1549855:AY555 RS09760
gene id: 1549855:AY555_RS09760
uniprot id: A0A143DGH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1549855:AY555 RS01150
gene id: 1549855:AY555_RS01150
uniprot id: A0A143DBP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1549855:AY555 RS02295
gene id: 1549855:AY555_RS02295
uniprot id: A0A143DC72
names: Similarity
messages: Belongs to the threonine synthase family.

1549855:AY555 RS00320
gene id: 1549855:AY555_RS00320
uniprot id: A0A143DCM6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1549855:AY555 RS10395
gene id: 1549855:AY555_RS10395
uniprot id: A0A143DGS5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1549855:AY555 RS05875
gene id: 1549855:AY555_RS05875
uniprot id: A0A143DDH4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1549855:AY555 RS08155
gene id: 1549855:AY555_RS08155
uniprot id: A0A143DEI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS03535
gene id: 1549855:AY555_RS03535
uniprot id: A0A143DCE8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1549855:AY555 RS01465
gene id: 1549855:AY555_RS01465
uniprot id: A0A143DBU4
names: PTM
messages: Binds 1 heme group per subunit.

1549855:AY555 RS00685
gene id: 1549855:AY555_RS00685
uniprot id: A0A143DB60
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1549855:AY555 RS00925
gene id: 1549855:AY555_RS00925
uniprot id: A0A143DFZ1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1549855:AY555 RS09095
gene id: 1549855:AY555_RS09095
uniprot id: A0A143DG84
names: Subcellular Location Annotation
messages: Cell inner membrane

1549855:AY555 RS09110
gene id: 1549855:AY555_RS09110
uniprot id: A0A143DF67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1549855:AY555 RS01660
gene id: 1549855:AY555_RS01660
uniprot id: A0A143DBX0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1549855:AY555 RS06765
gene id: 1549855:AY555_RS06765
uniprot id: A0A143DFQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS09290
gene id: 1549855:AY555_RS09290
uniprot id: A0A143DGR4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1549855:AY555 RS05030
gene id: 1549855:AY555_RS05030
uniprot id: A0A143DD97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1549855:AY555 RS04070
gene id: 1549855:AY555_RS04070
uniprot id: A0A143DCQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1549855:AY555 RS01975
gene id: 1549855:AY555_RS01975
uniprot id: A0A143DBW7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1549855:AY555 RS01475
gene id: 1549855:AY555_RS01475
uniprot id: A0A143DBE0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1549855:AY555 RS08085
gene id: 1549855:AY555_RS08085
uniprot id: A0A143DF36
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1549855:AY555 RS08080
gene id: 1549855:AY555_RS08080
uniprot id: A0A143DEY2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1549855:AY555 RS00850
gene id: 1549855:AY555_RS00850
uniprot id: A0A143DB52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1549855:AY555 RS04825
gene id: 1549855:AY555_RS04825
uniprot id: A0A143DEC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1549855:AY555 RS08180
gene id: 1549855:AY555_RS08180
uniprot id: A0A143DGH5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1549855:AY555 RS08770
gene id: 1549855:AY555_RS08770
uniprot id: A0A143DEQ9
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1549855:AY555 RS07910
gene id: 1549855:AY555_RS07910
uniprot id: A0A143DF05
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

1549855:AY555 RS04420
gene id: 1549855:AY555_RS04420
uniprot id: A0A143DCV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1549855:AY555 RS10525
gene id: 1549855:AY555_RS10525
uniprot id: A0A143DGC4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1549855:AY555 RS10040
gene id: 1549855:AY555_RS10040
uniprot id: A0A143DG11
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

1549855:AY555 RS02665
gene id: 1549855:AY555_RS02665
uniprot id: A0A143DC15
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1549855:AY555 RS06935
gene id: 1549855:AY555_RS06935
uniprot id: A0A143DE11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1549855:AY555 RS04760
gene id: 1549855:AY555_RS04760
uniprot id: A0A143DD02
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1549855:AY555 RS09720
gene id: 1549855:AY555_RS09720
uniprot id: A0A143DFU0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

1549855:AY555 RS01810
gene id: 1549855:AY555_RS01810
uniprot id: A0A143DBM1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1549855:AY555 RS09685
gene id: 1549855:AY555_RS09685
uniprot id: A0A143DGH4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1549855:AY555 RS05300
gene id: 1549855:AY555_RS05300
uniprot id: A0A143DEY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1549855:AY555 RS07200
gene id: 1549855:AY555_RS07200
uniprot id: A0A143DE46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1549855:AY555 RS07735
gene id: 1549855:AY555_RS07735
uniprot id: A0A143DEC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1549855:AY555 RS06755
gene id: 1549855:AY555_RS06755
uniprot id: A0A143DE36
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1549855:AY555 RS02680
gene id: 1549855:AY555_RS02680
uniprot id: A0A143DC16
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1549855:AY555 RS09405
gene id: 1549855:AY555_RS09405
uniprot id: A0A143DFL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1549855:AY555 RS07860
gene id: 1549855:AY555_RS07860
uniprot id: A0A143DEZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1549855:AY555 RS07270
gene id: 1549855:AY555_RS07270
uniprot id: A0A143DFX4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.