1547283:A9C19 RS10555
gene id: 1547283:A9C19_RS10555
uniprot id: A0A1L3MS20
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1547283:A9C19 RS11230
gene id: 1547283:A9C19_RS11230
uniprot id: A0A1L3MSC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1547283:A9C19 RS20435
gene id: 1547283:A9C19_RS20435
uniprot id: A0A1L3MWX4
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1547283:A9C19 RS13300
gene id: 1547283:A9C19_RS13300
uniprot id: A0A1L3MTE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1547283:A9C19 RS22030
gene id: 1547283:A9C19_RS22030
uniprot id: A0A1L3MSJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1547283:A9C19 RS08315
gene id: 1547283:A9C19_RS08315
uniprot id: A0A1L3MQW3
names: Similarity
messages: Belongs to the CapA family.

1547283:A9C19 RS11760
gene id: 1547283:A9C19_RS11760
uniprot id: A0A1L3MSQ9
names: Similarity
messages: Belongs to the YggT family.

1547283:A9C19 RS08480
gene id: 1547283:A9C19_RS08480
uniprot id: A0A1L3MQY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1547283:A9C19 RS16260
gene id: 1547283:A9C19_RS16260
uniprot id: A0A1L3MUW1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1547283:A9C19 RS20595
gene id: 1547283:A9C19_RS20595
uniprot id: A0A1L3MWV4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

1547283:A9C19 RS12605
gene id: 1547283:A9C19_RS12605
uniprot id: A0A1L3MT27
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1547283:A9C19 RS04690
gene id: 1547283:A9C19_RS04690
uniprot id: A0A1L3MP02
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1547283:A9C19 RS07695
gene id: 1547283:A9C19_RS07695
uniprot id: A0A1L3MQK0
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1547283:A9C19 RS10575
gene id: 1547283:A9C19_RS10575
uniprot id: A0A1L3MS16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS14200
gene id: 1547283:A9C19_RS14200
uniprot id: A0A1L3MXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS18825
gene id: 1547283:A9C19_RS18825
uniprot id: A0A1L3MW32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1547283:A9C19 RS09410
gene id: 1547283:A9C19_RS09410
uniprot id: A0A1L3MRG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS01805
gene id: 1547283:A9C19_RS01805
uniprot id: A0A1L3MMJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1547283:A9C19 RS02810
gene id: 1547283:A9C19_RS02810
uniprot id: A0A1L3MN27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS03895
gene id: 1547283:A9C19_RS03895
uniprot id: A0A1L3MNN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1547283:A9C19 RS17825
gene id: 1547283:A9C19_RS17825
uniprot id: A0A1L3MVN6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS02290
gene id: 1547283:A9C19_RS02290
uniprot id: A0A1L3MMU4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1547283:A9C19 RS08265
gene id: 1547283:A9C19_RS08265
uniprot id: A0A1L3MQV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1547283:A9C19 RS19365
gene id: 1547283:A9C19_RS19365
uniprot id: A0A1L3MWA2
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS16660
gene id: 1547283:A9C19_RS16660
uniprot id: A0A1L3MV23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS02890
gene id: 1547283:A9C19_RS02890
uniprot id: A0A1L3MN91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1547283:A9C19 RS12340
gene id: 1547283:A9C19_RS12340
uniprot id: A0A1L3MSW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1547283:A9C19 RS11530
gene id: 1547283:A9C19_RS11530
uniprot id: A0A1L3MSJ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1547283:A9C19 RS03395
gene id: 1547283:A9C19_RS03395
uniprot id: A0A1L3MNI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1547283:A9C19 RS05390
gene id: 1547283:A9C19_RS05390
uniprot id: A0A1L3MPB7
names: Similarity
messages: Belongs to the peptidase S16 family.

1547283:A9C19 RS19595
gene id: 1547283:A9C19_RS19595
uniprot id: A0A1L3MWF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1547283:A9C19 RS08665
gene id: 1547283:A9C19_RS08665
uniprot id: A0A1L3MR35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1547283:A9C19 RS10900
gene id: 1547283:A9C19_RS10900
uniprot id: A0A1L3MS63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1547283:A9C19 RS03820
gene id: 1547283:A9C19_RS03820
uniprot id: A0A1L3MNL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS16145
gene id: 1547283:A9C19_RS16145
uniprot id: A0A1L3MUT3
names: Similarity
messages: Belongs to the universal stress protein A family.

1547283:A9C19 RS09205
gene id: 1547283:A9C19_RS09205
uniprot id: A0A1L3MRA5
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

1547283:A9C19 RS04845
gene id: 1547283:A9C19_RS04845
uniprot id: A0A1L3MP26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1547283:A9C19 RS07230
gene id: 1547283:A9C19_RS07230
uniprot id: A0A1L3MQA4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Component of the MPD complex composed of SpoIIM, SpoIIP and SpoIID.
messages: Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane.

1547283:A9C19 RS20140
gene id: 1547283:A9C19_RS20140
uniprot id: A0A1L3MWN0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1547283:A9C19 RS00610
gene id: 1547283:A9C19_RS00610
uniprot id: A0A1L3MLY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RacA family.
messages: Cytoplasm
messages: Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure.

1547283:A9C19 RS01960
gene id: 1547283:A9C19_RS01960
uniprot id: A0A1L3MMN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1547283:A9C19 RS04075
gene id: 1547283:A9C19_RS04075
uniprot id: A0A1L3MNQ2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1547283:A9C19 RS19455
gene id: 1547283:A9C19_RS19455
uniprot id: A0A1L3MWC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1547283:A9C19 RS19900
gene id: 1547283:A9C19_RS19900
uniprot id: A0A1L3MWJ6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1547283:A9C19 RS06370
gene id: 1547283:A9C19_RS06370
uniprot id: A0A1L3MPW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS11410
gene id: 1547283:A9C19_RS11410
uniprot id: A0A1L3MSG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1547283:A9C19 RS13080
gene id: 1547283:A9C19_RS13080
uniprot id: A0A1L3MTF0
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1547283:A9C19 RS03115
gene id: 1547283:A9C19_RS03115
uniprot id: A0A1L3MN76
names: Similarity
messages: Belongs to the UPF0349 family.

1547283:A9C19 RS02775
gene id: 1547283:A9C19_RS02775
uniprot id: A0A1L3MN23
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS17250
gene id: 1547283:A9C19_RS17250
uniprot id: A0A1L3MV93
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS13510
gene id: 1547283:A9C19_RS13510
uniprot id: A0A1L3MTH5
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS14460
gene id: 1547283:A9C19_RS14460
uniprot id: A0A1L3MTY1
names: Similarity
messages: Belongs to the PdxA family. PdxA2 subfamily.

1547283:A9C19 RS20450
gene id: 1547283:A9C19_RS20450
uniprot id: A0A1L3MWT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1547283:A9C19 RS14400
gene id: 1547283:A9C19_RS14400
uniprot id: A0A1L3MTW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

1547283:A9C19 RS11420
gene id: 1547283:A9C19_RS11420
uniprot id: A0A1L3MSF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS15005
gene id: 1547283:A9C19_RS15005
uniprot id: A0A1L3MU83
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1547283:A9C19 RS13460
gene id: 1547283:A9C19_RS13460
uniprot id: A0A1L3MTH0
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS16255
gene id: 1547283:A9C19_RS16255
uniprot id: A0A1L3MUV5
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1547283:A9C19 RS19540
gene id: 1547283:A9C19_RS19540
uniprot id: A0A1L3MWD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1547283:A9C19 RS11035
gene id: 1547283:A9C19_RS11035
uniprot id: A0A1L3MS93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1547283:A9C19 RS11235
gene id: 1547283:A9C19_RS11235
uniprot id: A0A1L3MSA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1547283:A9C19 RS03420
gene id: 1547283:A9C19_RS03420
uniprot id: A0A1L3MNG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1547283:A9C19 RS20930
gene id: 1547283:A9C19_RS20930
uniprot id: A0A1L3MX00
names: Similarity
messages: Belongs to the WXG100 family.

1547283:A9C19 RS11545
gene id: 1547283:A9C19_RS11545
uniprot id: A0A1L3MXK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1547283:A9C19 RS19460
gene id: 1547283:A9C19_RS19460
uniprot id: A0A1L3MWC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1547283:A9C19 RS15215
gene id: 1547283:A9C19_RS15215
uniprot id: A0A1L3MUC5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1547283:A9C19 RS01890
gene id: 1547283:A9C19_RS01890
uniprot id: A0A1L3MMM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1547283:A9C19 RS18475
gene id: 1547283:A9C19_RS18475
uniprot id: A0A1L3MVZ5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1547283:A9C19 RS20980
gene id: 1547283:A9C19_RS20980
uniprot id: A0A1L3MX10
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1547283:A9C19 RS08205
gene id: 1547283:A9C19_RS08205
uniprot id: A0A1L3MXK0
names: Similarity
messages: Belongs to the SCO1/2 family.

1547283:A9C19 RS10240
gene id: 1547283:A9C19_RS10240
uniprot id: A0A1L3MRS5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1547283:A9C19 RS03765
gene id: 1547283:A9C19_RS03765
uniprot id: A0A1L3MNK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1547283:A9C19 RS07375
gene id: 1547283:A9C19_RS07375
uniprot id: A0A1L3MQE8
names: Similarity
messages: Belongs to the peptidase S11 family.

1547283:A9C19 RS07780
gene id: 1547283:A9C19_RS07780
uniprot id: A0A1L3MQK7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

1547283:A9C19 RS04320
gene id: 1547283:A9C19_RS04320
uniprot id: A0A1L3MNV5
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS10040
gene id: 1547283:A9C19_RS10040
uniprot id: A0A1L3MRY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07135
gene id: 1547283:A9C19_RS07135
uniprot id: A0A1L3MQD0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1547283:A9C19 RS14295
gene id: 1547283:A9C19_RS14295
uniprot id: A0A1L3MTV5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1547283:A9C19 RS14930
gene id: 1547283:A9C19_RS14930
uniprot id: A0A1L3MU56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS03000
gene id: 1547283:A9C19_RS03000
uniprot id: A0A1L3MNF0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1547283:A9C19 RS05970
gene id: 1547283:A9C19_RS05970
uniprot id: A0A1L3MPM4
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1547283:A9C19 RS00670
gene id: 1547283:A9C19_RS00670
uniprot id: A0A1L3MLZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS16460
gene id: 1547283:A9C19_RS16460
uniprot id: A0A1L3MUZ5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1547283:A9C19 RS09140
gene id: 1547283:A9C19_RS09140
uniprot id: A0A1L3MRB7
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS19755
gene id: 1547283:A9C19_RS19755
uniprot id: A0A1L3MWI5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1547283:A9C19 RS05300
gene id: 1547283:A9C19_RS05300
uniprot id: A0A1L3MP93
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1547283:A9C19 RS08160
gene id: 1547283:A9C19_RS08160
uniprot id: A0A1L3MQR3
names: Subcellular Location Annotation
messages: Secreted

1547283:A9C19 RS07575
gene id: 1547283:A9C19_RS07575
uniprot id: A0A1L3MQG7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1547283:A9C19 RS16595
gene id: 1547283:A9C19_RS16595
uniprot id: A0A1L3MV01
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS01990
gene id: 1547283:A9C19_RS01990
uniprot id: A0A1L3MMX6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1547283:A9C19 RS19745
gene id: 1547283:A9C19_RS19745
uniprot id: A0A1L3MY13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

1547283:A9C19 RS15745
gene id: 1547283:A9C19_RS15745
uniprot id: A0A1L3MUK1
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1547283:A9C19 RS00260
gene id: 1547283:A9C19_RS00260
uniprot id: A0A1L3MLT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07775
gene id: 1547283:A9C19_RS07775
uniprot id: A0A1L3MQL0
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

1547283:A9C19 RS04125
gene id: 1547283:A9C19_RS04125
uniprot id: A0A1L3MNP1
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1547283:A9C19 RS20010
gene id: 1547283:A9C19_RS20010
uniprot id: A0A1L3MWL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1547283:A9C19 RS11875
gene id: 1547283:A9C19_RS11875
uniprot id: A0A1L3MSS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1547283:A9C19 RS20670
gene id: 1547283:A9C19_RS20670
uniprot id: A0A1L3MWV8
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1547283:A9C19 RS16305
gene id: 1547283:A9C19_RS16305
uniprot id: A0A1L3MUW8
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1547283:A9C19 RS11040
gene id: 1547283:A9C19_RS11040
uniprot id: A0A1L3MSC9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1547283:A9C19 RS11620
gene id: 1547283:A9C19_RS11620
uniprot id: A0A1L3MSJ1
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1547283:A9C19 RS11775
gene id: 1547283:A9C19_RS11775
uniprot id: A0A1L3MSN4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1547283:A9C19 RS20325
gene id: 1547283:A9C19_RS20325
uniprot id: A0A1L3MWV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1547283:A9C19 RS05350
gene id: 1547283:A9C19_RS05350
uniprot id: A0A1L3MPB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1547283:A9C19 RS16185
gene id: 1547283:A9C19_RS16185
uniprot id: A0A1L3MUU4
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS06840
gene id: 1547283:A9C19_RS06840
uniprot id: A0A1L3MQ30
names: Similarity
messages: Belongs to the TlyA family.

1547283:A9C19 RS15910
gene id: 1547283:A9C19_RS15910
uniprot id: A0A1L3MUP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1547283:A9C19 RS04380
gene id: 1547283:A9C19_RS04380
uniprot id: A0A1L3MNT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07690
gene id: 1547283:A9C19_RS07690
uniprot id: A0A1L3MQI5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1547283:A9C19 RS19190
gene id: 1547283:A9C19_RS19190
uniprot id: A0A1L3MW92
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1547283:A9C19 RS04170
gene id: 1547283:A9C19_RS04170
uniprot id: A0A1L3MNP8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1547283:A9C19 RS10520
gene id: 1547283:A9C19_RS10520
uniprot id: A0A1L3MS05
names: Similarity
messages: Belongs to the glutamine synthetase family.

1547283:A9C19 RS14700
gene id: 1547283:A9C19_RS14700
uniprot id: A0A1L3MU09
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1547283:A9C19 RS00910
gene id: 1547283:A9C19_RS00910
uniprot id: A0A1L3MME3
names: Similarity
messages: Belongs to the manganese catalase family.

1547283:A9C19 RS07535
gene id: 1547283:A9C19_RS07535
uniprot id: A0A1L3MQF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1547283:A9C19 RS11645
gene id: 1547283:A9C19_RS11645
uniprot id: A0A1L3MSK3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1547283:A9C19 RS11370
gene id: 1547283:A9C19_RS11370
uniprot id: A0A1L3MSE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1547283:A9C19 RS04175
gene id: 1547283:A9C19_RS04175
uniprot id: A0A1L3MNQ3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1547283:A9C19 RS06835
gene id: 1547283:A9C19_RS06835
uniprot id: A0A1L3MQ31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1547283:A9C19 RS15165
gene id: 1547283:A9C19_RS15165
uniprot id: A0A1L3MUG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS17780
gene id: 1547283:A9C19_RS17780
uniprot id: A0A1L3MVK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS06070
gene id: 1547283:A9C19_RS06070
uniprot id: A0A1L3MPR2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

1547283:A9C19 RS14535
gene id: 1547283:A9C19_RS14535
uniprot id: A0A1L3MTZ1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1547283:A9C19 RS11455
gene id: 1547283:A9C19_RS11455
uniprot id: A0A1L3MSL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1547283:A9C19 RS17885
gene id: 1547283:A9C19_RS17885
uniprot id: A0A1L3MVM8
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS05330
gene id: 1547283:A9C19_RS05330
uniprot id: A0A1L3MPA5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1547283:A9C19 RS05720
gene id: 1547283:A9C19_RS05720
uniprot id: A0A1L3MPH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1547283:A9C19 RS00545
gene id: 1547283:A9C19_RS00545
uniprot id: A0A1L3MLZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1547283:A9C19 RS06810
gene id: 1547283:A9C19_RS06810
uniprot id: A0A1L3MQ42
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1547283:A9C19 RS03380
gene id: 1547283:A9C19_RS03380
uniprot id: A0A1L3MND6
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS19340
gene id: 1547283:A9C19_RS19340
uniprot id: A0A1L3MXV9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Involved in the activation of the KinB signaling pathway of sporulation.

1547283:A9C19 RS17585
gene id: 1547283:A9C19_RS17585
uniprot id: A0A1L3MVI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1547283:A9C19 RS06945
gene id: 1547283:A9C19_RS06945
uniprot id: A0A1L3MQ61
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1547283:A9C19 RS03230
gene id: 1547283:A9C19_RS03230
uniprot id: A0A1L3MNI1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1547283:A9C19 RS06865
gene id: 1547283:A9C19_RS06865
uniprot id: A0A1L3MQ53
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1547283:A9C19 RS20025
gene id: 1547283:A9C19_RS20025
uniprot id: A0A1L3MWL0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS07505
gene id: 1547283:A9C19_RS07505
uniprot id: A0A1L3MQP5
names: Similarity
messages: Belongs to the asparaginase 1 family.

1547283:A9C19 RS04130
gene id: 1547283:A9C19_RS04130
uniprot id: A0A1L3MNP3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1547283:A9C19 RS05785
gene id: 1547283:A9C19_RS05785
uniprot id: A0A1L3MPJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS10995
gene id: 1547283:A9C19_RS10995
uniprot id: A0A1L3MS74
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS03415
gene id: 1547283:A9C19_RS03415
uniprot id: A0A1L3MNE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1547283:A9C19 RS12230
gene id: 1547283:A9C19_RS12230
uniprot id: A0A1L3MSV6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1547283:A9C19 RS11050
gene id: 1547283:A9C19_RS11050
uniprot id: A0A1L3MS98
names: Function
names: Subunit
messages: Dipicolinate synthase likely consists of DpaA and DpaB, since both proteins are required for DPA synthesis.
messages: Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA).

1547283:A9C19 RS12085
gene id: 1547283:A9C19_RS12085
uniprot id: A0A1L3MSX2
names: Similarity
messages: Belongs to the UPF0358 family.

1547283:A9C19 RS07370
gene id: 1547283:A9C19_RS07370
uniprot id: A0A1L3MQC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1547283:A9C19 RS01600
gene id: 1547283:A9C19_RS01600
uniprot id: A0A1L3MMJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1547283:A9C19 RS01265
gene id: 1547283:A9C19_RS01265
uniprot id: A0A1L3MX42
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS02925
gene id: 1547283:A9C19_RS02925
uniprot id: A0A1L3MN55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS06100
gene id: 1547283:A9C19_RS06100
uniprot id: A0A1L3MPQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1547283:A9C19 RS12750
gene id: 1547283:A9C19_RS12750
uniprot id: A0A1L3MT92
names: Similarity
messages: Belongs to the transpeptidase family.

1547283:A9C19 RS12485
gene id: 1547283:A9C19_RS12485
uniprot id: A0A1L3MSZ9
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS13995
gene id: 1547283:A9C19_RS13995
uniprot id: A0A1L3MTU2
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1547283:A9C19 RS18155
gene id: 1547283:A9C19_RS18155
uniprot id: A0A1L3MVS6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1547283:A9C19 RS00695
gene id: 1547283:A9C19_RS00695
uniprot id: A0A1L3MM08
names: Similarity
messages: Belongs to the UPF0340 family.

1547283:A9C19 RS04865
gene id: 1547283:A9C19_RS04865
uniprot id: A0A1L3MP74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1547283:A9C19 RS02585
gene id: 1547283:A9C19_RS02585
uniprot id: A0A1L3MMZ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1547283:A9C19 RS05335
gene id: 1547283:A9C19_RS05335
uniprot id: A0A1L3MPC3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1547283:A9C19 RS15055
gene id: 1547283:A9C19_RS15055
uniprot id: A0A1L3MU82
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS03470
gene id: 1547283:A9C19_RS03470
uniprot id: A0A1L3MNG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1547283:A9C19 RS18135
gene id: 1547283:A9C19_RS18135
uniprot id: A0A1L3MVS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1547283:A9C19 RS04930
gene id: 1547283:A9C19_RS04930
uniprot id: A0A1L3MPG1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1547283:A9C19 RS19390
gene id: 1547283:A9C19_RS19390
uniprot id: A0A1L3MWB7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1547283:A9C19 RS20240
gene id: 1547283:A9C19_RS20240
uniprot id: A0A1L3MWN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1547283:A9C19 RS14695
gene id: 1547283:A9C19_RS14695
uniprot id: A0A1L3MU37
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1547283:A9C19 RS09985
gene id: 1547283:A9C19_RS09985
uniprot id: A0A1L3MRX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS10280
gene id: 1547283:A9C19_RS10280
uniprot id: A0A1L3MRW6
names: Similarity
messages: Belongs to the CobH/CbiC family.

1547283:A9C19 RS02750
gene id: 1547283:A9C19_RS02750
uniprot id: A0A1L3MN25
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS07275
gene id: 1547283:A9C19_RS07275
uniprot id: A0A1L3MQK4
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

1547283:A9C19 RS20915
gene id: 1547283:A9C19_RS20915
uniprot id: A0A1L3MX27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS08595
gene id: 1547283:A9C19_RS08595
uniprot id: A0A1L3MR05
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1547283:A9C19 RS19465
gene id: 1547283:A9C19_RS19465
uniprot id: A0A1L3MWB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07420
gene id: 1547283:A9C19_RS07420
uniprot id: A0A1L3MQD3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1547283:A9C19 RS00475
gene id: 1547283:A9C19_RS00475
uniprot id: A0A1L3MM68
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1547283:A9C19 RS17075
gene id: 1547283:A9C19_RS17075
uniprot id: A0A1L3MV59
names: Similarity
messages: Belongs to the gamma-type SASP family.

1547283:A9C19 RS08995
gene id: 1547283:A9C19_RS08995
uniprot id: A0A1L3MR62
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS06685
gene id: 1547283:A9C19_RS06685
uniprot id: A0A1L3MPZ6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1547283:A9C19 RS20375
gene id: 1547283:A9C19_RS20375
uniprot id: A0A1L3MWW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

1547283:A9C19 RS08850
gene id: 1547283:A9C19_RS08850
uniprot id: A0A1L3MR45
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1547283:A9C19 RS15125
gene id: 1547283:A9C19_RS15125
uniprot id: A0A1L3MUA3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.
messages: Homodimer.
messages: The N-terminal domain has binding sites for ComK and probably for unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1547283:A9C19 RS04475
gene id: 1547283:A9C19_RS04475
uniprot id: A0A1L3MNU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1547283:A9C19 RS18460
gene id: 1547283:A9C19_RS18460
uniprot id: A0A1L3MXV6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1547283:A9C19 RS05930
gene id: 1547283:A9C19_RS05930
uniprot id: A0A1L3MPM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

1547283:A9C19 RS20770
gene id: 1547283:A9C19_RS20770
uniprot id: A0A1L3MWY9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1547283:A9C19 RS12615
gene id: 1547283:A9C19_RS12615
uniprot id: A0A1L3MT12
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1547283:A9C19 RS15515
gene id: 1547283:A9C19_RS15515
uniprot id: A0A1L3MUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS05780
gene id: 1547283:A9C19_RS05780
uniprot id: A0A1L3MPI6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1547283:A9C19 RS08165
gene id: 1547283:A9C19_RS08165
uniprot id: A0A1L3MQU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS08715
gene id: 1547283:A9C19_RS08715
uniprot id: A0A1L3MQY6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1547283:A9C19 RS00875
gene id: 1547283:A9C19_RS00875
uniprot id: A0A1L3MM35
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1547283:A9C19 RS11835
gene id: 1547283:A9C19_RS11835
uniprot id: A0A1L3MSM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS08475
gene id: 1547283:A9C19_RS08475
uniprot id: A0A1L3MQX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1547283:A9C19 RS16055
gene id: 1547283:A9C19_RS16055
uniprot id: A0A1L3MUS9
names: Similarity
messages: Belongs to the UPF0754 family.

1547283:A9C19 RS20015
gene id: 1547283:A9C19_RS20015
uniprot id: A0A1L3MWL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1547283:A9C19 RS06530
gene id: 1547283:A9C19_RS06530
uniprot id: A0A1L3MPZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1547283:A9C19 RS15080
gene id: 1547283:A9C19_RS15080
uniprot id: A0A1L3MU81
names: Similarity
messages: Belongs to the UPF0738 family.

1547283:A9C19 RS15325
gene id: 1547283:A9C19_RS15325
uniprot id: A0A1L3MUD1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1547283:A9C19 RS07235
gene id: 1547283:A9C19_RS07235
uniprot id: A0A1L3MQA3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1547283:A9C19 RS13020
gene id: 1547283:A9C19_RS13020
uniprot id: A0A1L3MT98
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. MtnX family.
messages: Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).

1547283:A9C19 RS11665
gene id: 1547283:A9C19_RS11665
uniprot id: A0A1L3MSL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1547283:A9C19 RS05450
gene id: 1547283:A9C19_RS05450
uniprot id: A0A1L3MPE0
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1547283:A9C19 RS17560
gene id: 1547283:A9C19_RS17560
uniprot id: A0A1L3MVH1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1547283:A9C19 RS13320
gene id: 1547283:A9C19_RS13320
uniprot id: A0A1L3MTJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS06260
gene id: 1547283:A9C19_RS06260
uniprot id: A0A1L3MPS8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1547283:A9C19 RS11705
gene id: 1547283:A9C19_RS11705
uniprot id: A0A1L3MSP7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1547283:A9C19 RS14410
gene id: 1547283:A9C19_RS14410
uniprot id: A0A1L3MTX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1547283:A9C19 RS14465
gene id: 1547283:A9C19_RS14465
uniprot id: A0A1L3MTY4
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1547283:A9C19 RS11925
gene id: 1547283:A9C19_RS11925
uniprot id: A0A1L3MSQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS05540
gene id: 1547283:A9C19_RS05540
uniprot id: A0A1L3MPE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1547283:A9C19 RS06815
gene id: 1547283:A9C19_RS06815
uniprot id: A0A1L3MQ22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1547283:A9C19 RS11245
gene id: 1547283:A9C19_RS11245
uniprot id: A0A1L3MSH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1547283:A9C19 RS05840
gene id: 1547283:A9C19_RS05840
uniprot id: A0A1L3MPK7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1547283:A9C19 RS08125
gene id: 1547283:A9C19_RS08125
uniprot id: A0A1L3MQQ9
names: Similarity
messages: Belongs to the peptidase C40 family.

1547283:A9C19 RS16295
gene id: 1547283:A9C19_RS16295
uniprot id: A0A1L3MUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS10830
gene id: 1547283:A9C19_RS10830
uniprot id: A0A1L3MSA6
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS20500
gene id: 1547283:A9C19_RS20500
uniprot id: A0A1L3MWT2
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS11345
gene id: 1547283:A9C19_RS11345
uniprot id: A0A1L3MSF5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1547283:A9C19 RS07930
gene id: 1547283:A9C19_RS07930
uniprot id: A0A1L3MQQ0
names: Similarity
messages: Belongs to the UPF0398 family.

1547283:A9C19 RS12055
gene id: 1547283:A9C19_RS12055
uniprot id: A0A1L3MSS1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

1547283:A9C19 RS16170
gene id: 1547283:A9C19_RS16170
uniprot id: A0A1L3MUS8
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS14075
gene id: 1547283:A9C19_RS14075
uniprot id: A0A1L3MTT8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

1547283:A9C19 RS19625
gene id: 1547283:A9C19_RS19625
uniprot id: A0A1L3MWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1547283:A9C19 RS06240
gene id: 1547283:A9C19_RS06240
uniprot id: A0A1L3MPW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1547283:A9C19 RS08970
gene id: 1547283:A9C19_RS08970
uniprot id: A0A1L3MR82
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1547283:A9C19 RS19350
gene id: 1547283:A9C19_RS19350
uniprot id: A0A1L3MWA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1547283:A9C19 RS07010
gene id: 1547283:A9C19_RS07010
uniprot id: A0A1L3MQ56
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS02825
gene id: 1547283:A9C19_RS02825
uniprot id: A0A1L3MN33
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1547283:A9C19 RS09575
gene id: 1547283:A9C19_RS09575
uniprot id: A0A1L3MRI5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS19875
gene id: 1547283:A9C19_RS19875
uniprot id: A0A1L3MWN5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1547283:A9C19 RS19250
gene id: 1547283:A9C19_RS19250
uniprot id: A0A1L3MWA4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1547283:A9C19 RS00155
gene id: 1547283:A9C19_RS00155
uniprot id: A0A1L3MLS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1547283:A9C19 RS13070
gene id: 1547283:A9C19_RS13070
uniprot id: A0A1L3MT91
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS10465
gene id: 1547283:A9C19_RS10465
uniprot id: A0A1L3MRW9
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspN family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

1547283:A9C19 RS01055
gene id: 1547283:A9C19_RS01055
uniprot id: A0A1L3MM70
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS01675
gene id: 1547283:A9C19_RS01675
uniprot id: A0A1L3MMR8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1547283:A9C19 RS04800
gene id: 1547283:A9C19_RS04800
uniprot id: A0A1L3MP35
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1547283:A9C19 RS04090
gene id: 1547283:A9C19_RS04090
uniprot id: A0A1L3MXA4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS04410
gene id: 1547283:A9C19_RS04410
uniprot id: A0A1L3MNT6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1547283:A9C19 RS00370
gene id: 1547283:A9C19_RS00370
uniprot id: A0A1L3MLU0
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1547283:A9C19 RS12405
gene id: 1547283:A9C19_RS12405
uniprot id: A0A1L3MSX0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1547283:A9C19 RS03030
gene id: 1547283:A9C19_RS03030
uniprot id: A0A1L3MN73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1547283:A9C19 RS08040
gene id: 1547283:A9C19_RS08040
uniprot id: A0A1L3MQV0
names: Similarity
messages: Belongs to the EamA transporter family.

1547283:A9C19 RS02070
gene id: 1547283:A9C19_RS02070
uniprot id: A0A1L3MMQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1547283:A9C19 RS20370
gene id: 1547283:A9C19_RS20370
uniprot id: A0A1L3MWQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1547283:A9C19 RS11330
gene id: 1547283:A9C19_RS11330
uniprot id: A0A1L3MSJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell membrane
messages: Membrane
messages: One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation.

1547283:A9C19 RS20065
gene id: 1547283:A9C19_RS20065
uniprot id: A0A1L3MWM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1547283:A9C19 RS14335
gene id: 1547283:A9C19_RS14335
uniprot id: A0A1L3MTW7
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS08950
gene id: 1547283:A9C19_RS08950
uniprot id: A0A1L3MR98
names: Similarity
messages: Belongs to the UPF0473 family.

1547283:A9C19 RS07655
gene id: 1547283:A9C19_RS07655
uniprot id: A0A1L3MQI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1547283:A9C19 RS11240
gene id: 1547283:A9C19_RS11240
uniprot id: A0A1L3MSD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1547283:A9C19 RS11915
gene id: 1547283:A9C19_RS11915
uniprot id: A0A1L3MSN5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1547283:A9C19 RS11575
gene id: 1547283:A9C19_RS11575
uniprot id: A0A1L3MXJ9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1547283:A9C19 RS04870
gene id: 1547283:A9C19_RS04870
uniprot id: A0A1L3MP20
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS19605
gene id: 1547283:A9C19_RS19605
uniprot id: A0A1L3MWF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1547283:A9C19 RS11075
gene id: 1547283:A9C19_RS11075
uniprot id: A0A1L3MS87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1547283:A9C19 RS15250
gene id: 1547283:A9C19_RS15250
uniprot id: A0A1L3MUB1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS09125
gene id: 1547283:A9C19_RS09125
uniprot id: A0A1L3MR94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1547283:A9C19 RS08555
gene id: 1547283:A9C19_RS08555
uniprot id: A0A1L3MR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS05945
gene id: 1547283:A9C19_RS05945
uniprot id: A0A1L3MPM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1547283:A9C19 RS12420
gene id: 1547283:A9C19_RS12420
uniprot id: A0A1L3MSY1
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS20245
gene id: 1547283:A9C19_RS20245
uniprot id: A0A1L3MWR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1547283:A9C19 RS05535
gene id: 1547283:A9C19_RS05535
uniprot id: A0A1L3MPI7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

1547283:A9C19 RS07330
gene id: 1547283:A9C19_RS07330
uniprot id: A0A1L3MQL4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1547283:A9C19 RS12395
gene id: 1547283:A9C19_RS12395
uniprot id: A0A1L3MSY9
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS16560
gene id: 1547283:A9C19_RS16560
uniprot id: A0A1L3MV73
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1547283:A9C19 RS17670
gene id: 1547283:A9C19_RS17670
uniprot id: A0A1L3MVI6
names: Similarity
messages: Belongs to the peptidase C56 family.

1547283:A9C19 RS04255
gene id: 1547283:A9C19_RS04255
uniprot id: A0A1L3MX77
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS16050
gene id: 1547283:A9C19_RS16050
uniprot id: A0A1L3MUS0
names: Similarity
messages: Belongs to the UPF0342 family.

1547283:A9C19 RS11885
gene id: 1547283:A9C19_RS11885
uniprot id: A0A1L3MSP0
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

1547283:A9C19 RS06645
gene id: 1547283:A9C19_RS06645
uniprot id: A0A1L3MQ90
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the octanoyltransferase LipM family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. The reaction proceeds via an octanoyl-thioester enzyme intermediate.
messages: Monomer.

1547283:A9C19 RS03060
gene id: 1547283:A9C19_RS03060
uniprot id: A0A1L3MN66
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1547283:A9C19 RS03325
gene id: 1547283:A9C19_RS03325
uniprot id: A0A1L3MNB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1547283:A9C19 RS11280
gene id: 1547283:A9C19_RS11280
uniprot id: A0A1L3MSD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1547283:A9C19 RS01655
gene id: 1547283:A9C19_RS01655
uniprot id: A0A1L3MMG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LytR/CpsA/Psr (LCP) family.
messages: Cell membrane
messages: May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).

1547283:A9C19 RS14370
gene id: 1547283:A9C19_RS14370
uniprot id: A0A1L3MTV9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS18685
gene id: 1547283:A9C19_RS18685
uniprot id: A0A1L3MW16
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1547283:A9C19 RS18210
gene id: 1547283:A9C19_RS18210
uniprot id: A0A1L3MVT1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

1547283:A9C19 RS13230
gene id: 1547283:A9C19_RS13230
uniprot id: A0A1L3MTD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS12520
gene id: 1547283:A9C19_RS12520
uniprot id: A0A1L3MT54
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1547283:A9C19 RS14210
gene id: 1547283:A9C19_RS14210
uniprot id: A0A1L3MTS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1547283:A9C19 RS15265
gene id: 1547283:A9C19_RS15265
uniprot id: A0A1L3MUC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1547283:A9C19 RS07550
gene id: 1547283:A9C19_RS07550
uniprot id: A0A1L3MQK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS07110
gene id: 1547283:A9C19_RS07110
uniprot id: A0A1L3MQ85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1547283:A9C19 RS15730
gene id: 1547283:A9C19_RS15730
uniprot id: A0A1L3MUK6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1547283:A9C19 RS10210
gene id: 1547283:A9C19_RS10210
uniprot id: A0A1L3MRU1
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1547283:A9C19 RS14115
gene id: 1547283:A9C19_RS14115
uniprot id: A0A1L3MTS0
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS18975
gene id: 1547283:A9C19_RS18975
uniprot id: A0A1L3MW48
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1547283:A9C19 RS06445
gene id: 1547283:A9C19_RS06445
uniprot id: A0A1L3MPW4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1547283:A9C19 RS00205
gene id: 1547283:A9C19_RS00205
uniprot id: A0A1L3MLS7
names: Similarity
messages: Belongs to the PspA/IM30 family.

1547283:A9C19 RS19660
gene id: 1547283:A9C19_RS19660
uniprot id: A0A1L3MWG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1547283:A9C19 RS04260
gene id: 1547283:A9C19_RS04260
uniprot id: A0A1L3MNR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1547283:A9C19 RS17475
gene id: 1547283:A9C19_RS17475
uniprot id: A0A1L3MVE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS20940
gene id: 1547283:A9C19_RS20940
uniprot id: A0A1L3MX09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EssB family.
messages: Membrane

1547283:A9C19 RS19035
gene id: 1547283:A9C19_RS19035
uniprot id: A0A1L3MW63
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS00570
gene id: 1547283:A9C19_RS00570
uniprot id: A0A1L3MM25
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1547283:A9C19 RS00410
gene id: 1547283:A9C19_RS00410
uniprot id: A0A1L3MM00
names: Similarity
messages: Belongs to the Dps family.

1547283:A9C19 RS00255
gene id: 1547283:A9C19_RS00255
uniprot id: A0A1L3MLU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS06215
gene id: 1547283:A9C19_RS06215
uniprot id: A0A1L3MPT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1547283:A9C19 RS14705
gene id: 1547283:A9C19_RS14705
uniprot id: A0A1L3MU24
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS14885
gene id: 1547283:A9C19_RS14885
uniprot id: A0A1L3MU69
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1547283:A9C19 RS08275
gene id: 1547283:A9C19_RS08275
uniprot id: A0A1L3MQS2
names: Similarity
messages: Belongs to the UPF0346 family.

1547283:A9C19 RS13785
gene id: 1547283:A9C19_RS13785
uniprot id: A0A1L3MTR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

1547283:A9C19 RS12060
gene id: 1547283:A9C19_RS12060
uniprot id: A0A1L3MST0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 1 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

1547283:A9C19 RS16975
gene id: 1547283:A9C19_RS16975
uniprot id: A0A1L3MV72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0295 family.
messages: Cell membrane

1547283:A9C19 RS12305
gene id: 1547283:A9C19_RS12305
uniprot id: A0A1L3MSV1
names: Similarity
messages: Belongs to the peptidase M29 family.

1547283:A9C19 RS01850
gene id: 1547283:A9C19_RS01850
uniprot id: A0A1L3MMM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1547283:A9C19 RS11065
gene id: 1547283:A9C19_RS11065
uniprot id: A0A1L3MSA0
names: Similarity
messages: Belongs to the peptidase M16 family.

1547283:A9C19 RS00865
gene id: 1547283:A9C19_RS00865
uniprot id: A0A1L3MM59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1547283:A9C19 RS02790
gene id: 1547283:A9C19_RS02790
uniprot id: A0A1L3MN41
names: Similarity
messages: Belongs to the manganese catalase family.

1547283:A9C19 RS18090
gene id: 1547283:A9C19_RS18090
uniprot id: A0A1L3MVQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1547283:A9C19 RS09870
gene id: 1547283:A9C19_RS09870
uniprot id: A0A1L3MRP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS06740
gene id: 1547283:A9C19_RS06740
uniprot id: A0A1L3MQ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1547283:A9C19 RS10540
gene id: 1547283:A9C19_RS10540
uniprot id: A0A1L3MS13
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1547283:A9C19 RS02090
gene id: 1547283:A9C19_RS02090
uniprot id: A0A1L3MMR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1547283:A9C19 RS13335
gene id: 1547283:A9C19_RS13335
uniprot id: A0A1L3MTE8
names: Similarity
messages: Belongs to the peptidase M20A family.

1547283:A9C19 RS07630
gene id: 1547283:A9C19_RS07630
uniprot id: A0A1L3MQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1547283:A9C19 RS18340
gene id: 1547283:A9C19_RS18340
uniprot id: A0A1L3MVW4
names: Similarity
messages: Belongs to the IucA/IucC family.

1547283:A9C19 RS14205
gene id: 1547283:A9C19_RS14205
uniprot id: A0A1L3MTT2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1547283:A9C19 RS07400
gene id: 1547283:A9C19_RS07400
uniprot id: A0A1L3MQC8
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS14900
gene id: 1547283:A9C19_RS14900
uniprot id: A0A1L3MU66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS04495
gene id: 1547283:A9C19_RS04495
uniprot id: A0A1L3MNU8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1547283:A9C19 RS17760
gene id: 1547283:A9C19_RS17760
uniprot id: A0A1L3MVL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS00620
gene id: 1547283:A9C19_RS00620
uniprot id: A0A1L3MM27
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1547283:A9C19 RS11750
gene id: 1547283:A9C19_RS11750
uniprot id: A0A1L3MSK7
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS15260
gene id: 1547283:A9C19_RS15260
uniprot id: A0A1L3MUC4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1547283:A9C19 RS16580
gene id: 1547283:A9C19_RS16580
uniprot id: A0A1L3MV20
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS10905
gene id: 1547283:A9C19_RS10905
uniprot id: A0A1L3MS71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1547283:A9C19 RS07450
gene id: 1547283:A9C19_RS07450
uniprot id: A0A1L3MQD2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1547283:A9C19 RS01080
gene id: 1547283:A9C19_RS01080
uniprot id: A0A1L3MMH3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1547283:A9C19 RS15960
gene id: 1547283:A9C19_RS15960
uniprot id: A0A1L3MUQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1547283:A9C19 RS06350
gene id: 1547283:A9C19_RS06350
uniprot id: A0A1L3MPU4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1547283:A9C19 RS13280
gene id: 1547283:A9C19_RS13280
uniprot id: A0A1L3MTD8
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS12545
gene id: 1547283:A9C19_RS12545
uniprot id: A0A1L3MT42
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1547283:A9C19 RS16465
gene id: 1547283:A9C19_RS16465
uniprot id: A0A1L3MUZ7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1547283:A9C19 RS18440
gene id: 1547283:A9C19_RS18440
uniprot id: A0A1L3MVZ1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1547283:A9C19 RS05520
gene id: 1547283:A9C19_RS05520
uniprot id: A0A1L3MPG6
names: Similarity
messages: Belongs to the GSP E family.

1547283:A9C19 RS02940
gene id: 1547283:A9C19_RS02940
uniprot id: A0A1L3MNA1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1547283:A9C19 RS06915
gene id: 1547283:A9C19_RS06915
uniprot id: A0A1L3MQ92
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1547283:A9C19 RS11255
gene id: 1547283:A9C19_RS11255
uniprot id: A0A1L3MSC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1547283:A9C19 RS00505
gene id: 1547283:A9C19_RS00505
uniprot id: A0A1L3MLX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1547283:A9C19 RS07625
gene id: 1547283:A9C19_RS07625
uniprot id: A0A1L3MQH8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1547283:A9C19 RS05595
gene id: 1547283:A9C19_RS05595
uniprot id: A0A1L3MPJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1547283:A9C19 RS19725
gene id: 1547283:A9C19_RS19725
uniprot id: A0A1L3MWH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1547283:A9C19 RS01345
gene id: 1547283:A9C19_RS01345
uniprot id: A0A1L3MMD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS11365
gene id: 1547283:A9C19_RS11365
uniprot id: A0A1L3MSG9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1547283:A9C19 RS18805
gene id: 1547283:A9C19_RS18805
uniprot id: A0A1L3MW34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1547283:A9C19 RS06095
gene id: 1547283:A9C19_RS06095
uniprot id: A0A1L3MQ03
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1547283:A9C19 RS05050
gene id: 1547283:A9C19_RS05050
uniprot id: A0A1L3MP58
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1547283:A9C19 RS09230
gene id: 1547283:A9C19_RS09230
uniprot id: A0A1L3MRA9
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS16555
gene id: 1547283:A9C19_RS16555
uniprot id: A0A1L3MV10
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

1547283:A9C19 RS13090
gene id: 1547283:A9C19_RS13090
uniprot id: A0A1L3MTA8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1547283:A9C19 RS02400
gene id: 1547283:A9C19_RS02400
uniprot id: A0A1L3MMW4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1547283:A9C19 RS11510
gene id: 1547283:A9C19_RS11510
uniprot id: A0A1L3MSI4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1547283:A9C19 RS02270
gene id: 1547283:A9C19_RS02270
uniprot id: A0A1L3MMT3
names: Similarity
messages: Belongs to the sigma-54 factor family.

1547283:A9C19 RS03280
gene id: 1547283:A9C19_RS03280
uniprot id: A0A1L3MNF6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1547283:A9C19 RS01445
gene id: 1547283:A9C19_RS01445
uniprot id: A0A1L3MMN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS17470
gene id: 1547283:A9C19_RS17470
uniprot id: A0A1L3MVG0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1547283:A9C19 RS17890
gene id: 1547283:A9C19_RS17890
uniprot id: A0A1L3MVN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

1547283:A9C19 RS14160
gene id: 1547283:A9C19_RS14160
uniprot id: A0A1L3MTX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1547283:A9C19 RS00590
gene id: 1547283:A9C19_RS00590
uniprot id: A0A1L3MM10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1547283:A9C19 RS13265
gene id: 1547283:A9C19_RS13265
uniprot id: A0A1L3MTD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SscA family.
messages: Membrane

1547283:A9C19 RS19620
gene id: 1547283:A9C19_RS19620
uniprot id: A0A1L3MWF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1547283:A9C19 RS17935
gene id: 1547283:A9C19_RS17935
uniprot id: A0A1L3MVP0
names: Similarity
messages: Belongs to the peptidase S8 family.

1547283:A9C19 RS12745
gene id: 1547283:A9C19_RS12745
uniprot id: A0A1L3MXS7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1547283:A9C19 RS18170
gene id: 1547283:A9C19_RS18170
uniprot id: A0A1L3MVY7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1547283:A9C19 RS18800
gene id: 1547283:A9C19_RS18800
uniprot id: A0A1L3MW24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1547283:A9C19 RS18025
gene id: 1547283:A9C19_RS18025
uniprot id: A0A1L3MVP1
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1547283:A9C19 RS17790
gene id: 1547283:A9C19_RS17790
uniprot id: A0A1L3MVJ7
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

1547283:A9C19 RS20830
gene id: 1547283:A9C19_RS20830
uniprot id: A0A1L3MWZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS12165
gene id: 1547283:A9C19_RS12165
uniprot id: A0A1L3MSY0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1547283:A9C19 RS12150
gene id: 1547283:A9C19_RS12150
uniprot id: A0A1L3MSS9
names: Similarity
messages: Belongs to the UPF0637 family.

1547283:A9C19 RS16540
gene id: 1547283:A9C19_RS16540
uniprot id: A0A1L3MUZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1547283:A9C19 RS04730
gene id: 1547283:A9C19_RS04730
uniprot id: A0A1L3MNZ8
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS07035
gene id: 1547283:A9C19_RS07035
uniprot id: A0A1L3MQ80
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1547283:A9C19 RS05035
gene id: 1547283:A9C19_RS05035
uniprot id: A0A1L3MP55
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1547283:A9C19 RS16620
gene id: 1547283:A9C19_RS16620
uniprot id: A0A1L3MV08
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1547283:A9C19 RS15980
gene id: 1547283:A9C19_RS15980
uniprot id: A0A1L3MUQ2
names: Function
names: Similarity
messages: Belongs to the YhaM family.
messages: Shows a 3'-5' exoribonuclease activity.

1547283:A9C19 RS02240
gene id: 1547283:A9C19_RS02240
uniprot id: A0A1L3MMS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1547283:A9C19 RS11250
gene id: 1547283:A9C19_RS11250
uniprot id: A0A1L3MSD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1547283:A9C19 RS00165
gene id: 1547283:A9C19_RS00165
uniprot id: A0A1L3MLS0
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1547283:A9C19 RS18175
gene id: 1547283:A9C19_RS18175
uniprot id: A0A1L3MVR5
names: Similarity
messages: Belongs to the CdaR family.

1547283:A9C19 RS05900
gene id: 1547283:A9C19_RS05900
uniprot id: A0A1L3MPK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1547283:A9C19 RS04195
gene id: 1547283:A9C19_RS04195
uniprot id: A0A1L3MNQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS04140
gene id: 1547283:A9C19_RS04140
uniprot id: A0A1L3MNP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS05105
gene id: 1547283:A9C19_RS05105
uniprot id: A0A1L3MP71
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1547283:A9C19 RS07670
gene id: 1547283:A9C19_RS07670
uniprot id: A0A1L3MQJ7
names: Similarity
messages: Belongs to the TrpF family.

1547283:A9C19 RS12065
gene id: 1547283:A9C19_RS12065
uniprot id: A0A1L3MST8
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1547283:A9C19 RS10235
gene id: 1547283:A9C19_RS10235
uniprot id: A0A1L3MRT3
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1547283:A9C19 RS05745
gene id: 1547283:A9C19_RS05745
uniprot id: A0A1L3MPI9
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS05375
gene id: 1547283:A9C19_RS05375
uniprot id: A0A1L3MPB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1547283:A9C19 RS01925
gene id: 1547283:A9C19_RS01925
uniprot id: A0A1L3MMQ6
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1547283:A9C19 RS14100
gene id: 1547283:A9C19_RS14100
uniprot id: A0A1L3MTS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1547283:A9C19 RS09960
gene id: 1547283:A9C19_RS09960
uniprot id: A0A1L3MRN0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1547283:A9C19 RS06795
gene id: 1547283:A9C19_RS06795
uniprot id: A0A1L3MQ74
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1547283:A9C19 RS18700
gene id: 1547283:A9C19_RS18700
uniprot id: A0A1L3MW13
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1547283:A9C19 RS16205
gene id: 1547283:A9C19_RS16205
uniprot id: A0A1L3MUU3
names: Similarity
messages: Belongs to the universal stress protein A family.

1547283:A9C19 RS04890
gene id: 1547283:A9C19_RS04890
uniprot id: A0A1L3MP34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

1547283:A9C19 RS01135
gene id: 1547283:A9C19_RS01135
uniprot id: A0A1L3MM91
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS01875
gene id: 1547283:A9C19_RS01875
uniprot id: A0A1L3MMQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1547283:A9C19 RS18335
gene id: 1547283:A9C19_RS18335
uniprot id: A0A1L3MVX0
names: Similarity
messages: Belongs to the IucA/IucC family.

1547283:A9C19 RS02085
gene id: 1547283:A9C19_RS02085
uniprot id: A0A1L3MMV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1547283:A9C19 RS05585
gene id: 1547283:A9C19_RS05585
uniprot id: A0A1L3MPF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1547283:A9C19 RS00985
gene id: 1547283:A9C19_RS00985
uniprot id: A0A1L3MM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS13095
gene id: 1547283:A9C19_RS13095
uniprot id: A0A1L3MTB0
names: Subcellular Location Annotation
messages: Cell membrane

1547283:A9C19 RS02605
gene id: 1547283:A9C19_RS02605
uniprot id: A0A1L3MN05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS00625
gene id: 1547283:A9C19_RS00625
uniprot id: A0A1L3MM38
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1547283:A9C19 RS05800
gene id: 1547283:A9C19_RS05800
uniprot id: A0A1L3MPL6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS02945
gene id: 1547283:A9C19_RS02945
uniprot id: A0A1L3MN49
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1547283:A9C19 RS09070
gene id: 1547283:A9C19_RS09070
uniprot id: A0A1L3MXI3
names: Similarity
messages: Belongs to the FGGY kinase family.

1547283:A9C19 RS07660
gene id: 1547283:A9C19_RS07660
uniprot id: A0A1L3MQT8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS10430
gene id: 1547283:A9C19_RS10430
uniprot id: A0A1L3MRX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1547283:A9C19 RS13395
gene id: 1547283:A9C19_RS13395
uniprot id: A0A1L3MTE9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1547283:A9C19 RS11655
gene id: 1547283:A9C19_RS11655
uniprot id: A0A1L3MSJ9
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1547283:A9C19 RS18465
gene id: 1547283:A9C19_RS18465
uniprot id: A0A1L3MVW7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1547283:A9C19 RS04105
gene id: 1547283:A9C19_RS04105
uniprot id: A0A1L3MP33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1547283:A9C19 RS02745
gene id: 1547283:A9C19_RS02745
uniprot id: A0A1L3MN24
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1547283:A9C19 RS11155
gene id: 1547283:A9C19_RS11155
uniprot id: A0A1L3MSD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1547283:A9C19 RS08675
gene id: 1547283:A9C19_RS08675
uniprot id: A0A1L3MR15
names: Similarity
messages: Belongs to the glutamate synthase family.

1547283:A9C19 RS01070
gene id: 1547283:A9C19_RS01070
uniprot id: A0A1L3MMB9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1547283:A9C19 RS09145
gene id: 1547283:A9C19_RS09145
uniprot id: A0A1L3MRC0
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1547283:A9C19 RS11585
gene id: 1547283:A9C19_RS11585
uniprot id: A0A1L3MSN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1547283:A9C19 RS12215
gene id: 1547283:A9C19_RS12215
uniprot id: A0A1L3MSV3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1547283:A9C19 RS04065
gene id: 1547283:A9C19_RS04065
uniprot id: A0A1L3MX85
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1547283:A9C19 RS12550
gene id: 1547283:A9C19_RS12550
uniprot id: A0A1L3MT07
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1547283:A9C19 RS04920
gene id: 1547283:A9C19_RS04920
uniprot id: A0A1L3MP83
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS10395
gene id: 1547283:A9C19_RS10395
uniprot id: A0A1L3MRX6
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS15520
gene id: 1547283:A9C19_RS15520
uniprot id: A0A1L3MUG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS16000
gene id: 1547283:A9C19_RS16000
uniprot id: A0A1L3MUR7
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS08000
gene id: 1547283:A9C19_RS08000
uniprot id: A0A1L3MQN1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1547283:A9C19 RS18370
gene id: 1547283:A9C19_RS18370
uniprot id: A0A1L3MVW2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

1547283:A9C19 RS06690
gene id: 1547283:A9C19_RS06690
uniprot id: A0A1L3MPZ7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1547283:A9C19 RS09730
gene id: 1547283:A9C19_RS09730
uniprot id: A0A1L3MRM0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1547283:A9C19 RS01095
gene id: 1547283:A9C19_RS01095
uniprot id: A0A1L3MM93
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1547283:A9C19 RS01720
gene id: 1547283:A9C19_RS01720
uniprot id: A0A1L3MMJ0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1547283:A9C19 RS11680
gene id: 1547283:A9C19_RS11680
uniprot id: A0A1L3MSQ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS00745
gene id: 1547283:A9C19_RS00745
uniprot id: A0A1L3MMB8
names: Similarity
messages: Belongs to the peptidase S8 family.

1547283:A9C19 RS05715
gene id: 1547283:A9C19_RS05715
uniprot id: A0A1L3MPT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1547283:A9C19 RS02690
gene id: 1547283:A9C19_RS02690
uniprot id: A0A1L3MN14
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS13330
gene id: 1547283:A9C19_RS13330
uniprot id: A0A1L3MTE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).
messages: Homotetramer.

1547283:A9C19 RS01930
gene id: 1547283:A9C19_RS01930
uniprot id: A0A1L3MMR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1547283:A9C19 RS10455
gene id: 1547283:A9C19_RS10455
uniprot id: A0A1L3MS00
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1547283:A9C19 RS20955
gene id: 1547283:A9C19_RS20955
uniprot id: A0A1L3MX24
names: Similarity
messages: Belongs to the EssA family.

1547283:A9C19 RS00120
gene id: 1547283:A9C19_RS00120
uniprot id: A0A1L3MLR5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1547283:A9C19 RS09300
gene id: 1547283:A9C19_RS09300
uniprot id: A0A1L3MRD6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1547283:A9C19 RS01910
gene id: 1547283:A9C19_RS01910
uniprot id: A0A1L3MMM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1547283:A9C19 RS07800
gene id: 1547283:A9C19_RS07800
uniprot id: A0A1L3MQQ7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1547283:A9C19 RS05590
gene id: 1547283:A9C19_RS05590
uniprot id: A0A1L3MPE7
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1547283:A9C19 RS09060
gene id: 1547283:A9C19_RS09060
uniprot id: A0A1L3MRC2
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1547283:A9C19 RS15350
gene id: 1547283:A9C19_RS15350
uniprot id: A0A1L3MUD4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1547283:A9C19 RS04455
gene id: 1547283:A9C19_RS04455
uniprot id: A0A1L3MNT7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1547283:A9C19 RS19680
gene id: 1547283:A9C19_RS19680
uniprot id: A0A1L3MWG0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1547283:A9C19 RS10795
gene id: 1547283:A9C19_RS10795
uniprot id: A0A1L3MS55
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

1547283:A9C19 RS04955
gene id: 1547283:A9C19_RS04955
uniprot id: A0A1L3MP46
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1547283:A9C19 RS15310
gene id: 1547283:A9C19_RS15310
uniprot id: A0A1L3MUD0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS10800
gene id: 1547283:A9C19_RS10800
uniprot id: A0A1L3MS40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1547283:A9C19 RS15340
gene id: 1547283:A9C19_RS15340
uniprot id: A0A1L3MUJ3
names: Similarity
messages: Belongs to the UPF0234 family.

1547283:A9C19 RS06235
gene id: 1547283:A9C19_RS06235
uniprot id: A0A1L3MPS7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1547283:A9C19 RS05130
gene id: 1547283:A9C19_RS05130
uniprot id: A0A1L3MPD6
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1547283:A9C19 RS01575
gene id: 1547283:A9C19_RS01575
uniprot id: A0A1L3MMH5
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS10415
gene id: 1547283:A9C19_RS10415
uniprot id: A0A1L3MRV9
names: Similarity
messages: Belongs to the GbsR family.

1547283:A9C19 RS08075
gene id: 1547283:A9C19_RS08075
uniprot id: A0A1L3MQP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1547283:A9C19 RS15690
gene id: 1547283:A9C19_RS15690
uniprot id: A0A1L3MUL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

1547283:A9C19 RS02845
gene id: 1547283:A9C19_RS02845
uniprot id: A0A1L3MN37
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS00755
gene id: 1547283:A9C19_RS00755
uniprot id: A0A1L3MM14
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS17690
gene id: 1547283:A9C19_RS17690
uniprot id: A0A1L3MVH8
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS17415
gene id: 1547283:A9C19_RS17415
uniprot id: A0A1L3MVC2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1547283:A9C19 RS05110
gene id: 1547283:A9C19_RS05110
uniprot id: A0A1L3MP70
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1547283:A9C19 RS17720
gene id: 1547283:A9C19_RS17720
uniprot id: A0A1L3MVI7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

1547283:A9C19 RS00525
gene id: 1547283:A9C19_RS00525
uniprot id: A0A1L3MLX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS14550
gene id: 1547283:A9C19_RS14550
uniprot id: A0A1L3MU07
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1547283:A9C19 RS02725
gene id: 1547283:A9C19_RS02725
uniprot id: A0A1L3MN19
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS06275
gene id: 1547283:A9C19_RS06275
uniprot id: A0A1L3MPU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

1547283:A9C19 RS18560
gene id: 1547283:A9C19_RS18560
uniprot id: A0A1L3MVY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS15590
gene id: 1547283:A9C19_RS15590
uniprot id: A0A1L3MUG7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1547283:A9C19 RS01515
gene id: 1547283:A9C19_RS01515
uniprot id: A0A1L3MMG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS10075
gene id: 1547283:A9C19_RS10075
uniprot id: A0A1L3MRQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS10855
gene id: 1547283:A9C19_RS10855
uniprot id: A0A1L3MS49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1547283:A9C19 RS01780
gene id: 1547283:A9C19_RS01780
uniprot id: A0A1L3MMK0
names: Similarity
messages: Belongs to the FlgM family.

1547283:A9C19 RS04145
gene id: 1547283:A9C19_RS04145
uniprot id: A0A1L3MNU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS14365
gene id: 1547283:A9C19_RS14365
uniprot id: A0A1L3MTV6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1547283:A9C19 RS17695
gene id: 1547283:A9C19_RS17695
uniprot id: A0A1L3MVK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS11300
gene id: 1547283:A9C19_RS11300
uniprot id: A0A1L3MSI9
names: Similarity
messages: Belongs to the FlgD family.

1547283:A9C19 RS09210
gene id: 1547283:A9C19_RS09210
uniprot id: A0A1L3MR81
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1547283:A9C19 RS19535
gene id: 1547283:A9C19_RS19535
uniprot id: A0A1L3MWJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1547283:A9C19 RS07965
gene id: 1547283:A9C19_RS07965
uniprot id: A0A1L3MQN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1547283:A9C19 RS01730
gene id: 1547283:A9C19_RS01730
uniprot id: A0A1L3MMS7
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS05120
gene id: 1547283:A9C19_RS05120
uniprot id: A0A1L3MP80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1547283:A9C19 RS17725
gene id: 1547283:A9C19_RS17725
uniprot id: A0A1L3MVL5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1547283:A9C19 RS10340
gene id: 1547283:A9C19_RS10340
uniprot id: A0A1L3MXI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1547283:A9C19 RS04785
gene id: 1547283:A9C19_RS04785
uniprot id: A0A1L3MP04
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS06225
gene id: 1547283:A9C19_RS06225
uniprot id: A0A1L3MPT6
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1547283:A9C19 RS04325
gene id: 1547283:A9C19_RS04325
uniprot id: A0A1L3MNS2
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

1547283:A9C19 RS03390
gene id: 1547283:A9C19_RS03390
uniprot id: A0A1L3MNF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1547283:A9C19 RS02190
gene id: 1547283:A9C19_RS02190
uniprot id: A0A1L3MMV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1547283:A9C19 RS03785
gene id: 1547283:A9C19_RS03785
uniprot id: A0A1L3MNS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS06355
gene id: 1547283:A9C19_RS06355
uniprot id: A0A1L3MQ02
names: Subcellular Location Annotation
messages: Cell membrane

1547283:A9C19 RS11800
gene id: 1547283:A9C19_RS11800
uniprot id: A0A1L3MSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1547283:A9C19 RS03010
gene id: 1547283:A9C19_RS03010
uniprot id: A0A1L3MN78
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS12465
gene id: 1547283:A9C19_RS12465
uniprot id: A0A1L3MSZ5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1547283:A9C19 RS16225
gene id: 1547283:A9C19_RS16225
uniprot id: A0A1L3MUV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS20380
gene id: 1547283:A9C19_RS20380
uniprot id: A0A1L3MWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ParB family.
messages: Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
messages: nucleoid

1547283:A9C19 RS11550
gene id: 1547283:A9C19_RS11550
uniprot id: A0A1L3MSI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1547283:A9C19 RS12320
gene id: 1547283:A9C19_RS12320
uniprot id: A0A1L3MSV7
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS13600
gene id: 1547283:A9C19_RS13600
uniprot id: A0A1L3MTK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS20745
gene id: 1547283:A9C19_RS20745
uniprot id: A0A1L3MWY8
names: Similarity
messages: Belongs to the EamA transporter family.

1547283:A9C19 RS11450
gene id: 1547283:A9C19_RS11450
uniprot id: A0A1L3MSH7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1547283:A9C19 RS19735
gene id: 1547283:A9C19_RS19735
uniprot id: A0A1L3MWG9
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1547283:A9C19 RS02860
gene id: 1547283:A9C19_RS02860
uniprot id: A0A1L3MN44
names: Cofactor
messages: Binds 1 FAD per subunit.

1547283:A9C19 RS10300
gene id: 1547283:A9C19_RS10300
uniprot id: A0A1L3MRU2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1547283:A9C19 RS10685
gene id: 1547283:A9C19_RS10685
uniprot id: A0A1L3MS15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1547283:A9C19 RS03245
gene id: 1547283:A9C19_RS03245
uniprot id: A0A1L3MNC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1547283:A9C19 RS19395
gene id: 1547283:A9C19_RS19395
uniprot id: A0A1L3MWB1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1547283:A9C19 RS04100
gene id: 1547283:A9C19_RS04100
uniprot id: A0A1L3MNN7
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

1547283:A9C19 RS00055
gene id: 1547283:A9C19_RS00055
uniprot id: A0A1L3MLP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EsaA family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS11360
gene id: 1547283:A9C19_RS11360
uniprot id: A0A1L3MSF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1547283:A9C19 RS12410
gene id: 1547283:A9C19_RS12410
uniprot id: A0A1L3MSY5
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS18380
gene id: 1547283:A9C19_RS18380
uniprot id: A0A1L3MVV5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1547283:A9C19 RS07845
gene id: 1547283:A9C19_RS07845
uniprot id: A0A1L3MXD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1547283:A9C19 RS10530
gene id: 1547283:A9C19_RS10530
uniprot id: A0A1L3MRZ1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1547283:A9C19 RS09780
gene id: 1547283:A9C19_RS09780
uniprot id: A0A1L3MRJ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS08795
gene id: 1547283:A9C19_RS08795
uniprot id: A0A1L3MR52
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1547283:A9C19 RS06610
gene id: 1547283:A9C19_RS06610
uniprot id: A0A1L3MPZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1547283:A9C19 RS13250
gene id: 1547283:A9C19_RS13250
uniprot id: A0A1L3MTC3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1547283:A9C19 RS04850
gene id: 1547283:A9C19_RS04850
uniprot id: A0A1L3MP44
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1547283:A9C19 RS09220
gene id: 1547283:A9C19_RS09220
uniprot id: A0A1L3MRC8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1547283:A9C19 RS03875
gene id: 1547283:A9C19_RS03875
uniprot id: A0A1L3MNM3
names: Similarity
messages: Belongs to the UPF0045 family.

1547283:A9C19 RS02140
gene id: 1547283:A9C19_RS02140
uniprot id: A0A1L3MMU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1547283:A9C19 RS13295
gene id: 1547283:A9C19_RS13295
uniprot id: A0A1L3MTE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1547283:A9C19 RS04990
gene id: 1547283:A9C19_RS04990
uniprot id: A0A1L3MP49
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS06910
gene id: 1547283:A9C19_RS06910
uniprot id: A0A1L3MQ39
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1547283:A9C19 RS01945
gene id: 1547283:A9C19_RS01945
uniprot id: A0A1L3MMN1
names: Similarity
messages: Belongs to the peptidase S41A family.

1547283:A9C19 RS15430
gene id: 1547283:A9C19_RS15430
uniprot id: A0A1L3MUE1
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS06230
gene id: 1547283:A9C19_RS06230
uniprot id: A0A1L3MPT4
names: Similarity
messages: Belongs to the UPF0178 family.

1547283:A9C19 RS10460
gene id: 1547283:A9C19_RS10460
uniprot id: A0A1L3MRX2
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tlp family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

1547283:A9C19 RS05340
gene id: 1547283:A9C19_RS05340
uniprot id: A0A1L3MPB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1547283:A9C19 RS02180
gene id: 1547283:A9C19_RS02180
uniprot id: A0A1L3MMS3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1547283:A9C19 RS12050
gene id: 1547283:A9C19_RS12050
uniprot id: A0A1L3MXL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1547283:A9C19 RS06675
gene id: 1547283:A9C19_RS06675
uniprot id: A0A1L3MQ10
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

1547283:A9C19 RS05365
gene id: 1547283:A9C19_RS05365
uniprot id: A0A1L3MPG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1547283:A9C19 RS18035
gene id: 1547283:A9C19_RS18035
uniprot id: A0A1L3MVN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.
messages: Membrane

1547283:A9C19 RS15255
gene id: 1547283:A9C19_RS15255
uniprot id: A0A1L3MUB7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1547283:A9C19 RS07115
gene id: 1547283:A9C19_RS07115
uniprot id: A0A1L3MQ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS05055
gene id: 1547283:A9C19_RS05055
uniprot id: A0A1L3MP63
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1547283:A9C19 RS12490
gene id: 1547283:A9C19_RS12490
uniprot id: A0A1L3MT35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1547283:A9C19 RS16345
gene id: 1547283:A9C19_RS16345
uniprot id: A0A1L3MV29
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS20095
gene id: 1547283:A9C19_RS20095
uniprot id: A0A1L3MWS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1547283:A9C19 RS04765
gene id: 1547283:A9C19_RS04765
uniprot id: A0A1L3MP08
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1547283:A9C19 RS03425
gene id: 1547283:A9C19_RS03425
uniprot id: A0A1L3MNE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS19760
gene id: 1547283:A9C19_RS19760
uniprot id: A0A1L3MWI2
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.

1547283:A9C19 RS05470
gene id: 1547283:A9C19_RS05470
uniprot id: A0A1L3MPD1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1547283:A9C19 RS11720
gene id: 1547283:A9C19_RS11720
uniprot id: A0A1L3MSM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1547283:A9C19 RS08250
gene id: 1547283:A9C19_RS08250
uniprot id: A0A1L3MQV2
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS12790
gene id: 1547283:A9C19_RS12790
uniprot id: A0A1L3MT53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1547283:A9C19 RS08470
gene id: 1547283:A9C19_RS08470
uniprot id: A0A1L3MQY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1547283:A9C19 RS01500
gene id: 1547283:A9C19_RS01500
uniprot id: A0A1L3MMP1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1547283:A9C19 RS11390
gene id: 1547283:A9C19_RS11390
uniprot id: A0A1L3MSE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1547283:A9C19 RS01580
gene id: 1547283:A9C19_RS01580
uniprot id: A0A1L3MMH7
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS11120
gene id: 1547283:A9C19_RS11120
uniprot id: A0A1L3MSE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1547283:A9C19 RS11165
gene id: 1547283:A9C19_RS11165
uniprot id: A0A1L3MSB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1547283:A9C19 RS15560
gene id: 1547283:A9C19_RS15560
uniprot id: A0A1L3MUI6
names: Cofactor
messages: Can also use Mn(2+) ion.

1547283:A9C19 RS11350
gene id: 1547283:A9C19_RS11350
uniprot id: A0A1L3MSJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1547283:A9C19 RS12315
gene id: 1547283:A9C19_RS12315
uniprot id: A0A1L3MT13
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1547283:A9C19 RS11145
gene id: 1547283:A9C19_RS11145
uniprot id: A0A1L3MSB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1547283:A9C19 RS06025
gene id: 1547283:A9C19_RS06025
uniprot id: A0A1L3MXD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1547283:A9C19 RS12125
gene id: 1547283:A9C19_RS12125
uniprot id: A0A1L3MSU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1547283:A9C19 RS06190
gene id: 1547283:A9C19_RS06190
uniprot id: A0A1L3MPS4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1547283:A9C19 RS07415
gene id: 1547283:A9C19_RS07415
uniprot id: A0A1L3MQD5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS01065
gene id: 1547283:A9C19_RS01065
uniprot id: A0A1L3MX22
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1547283:A9C19 RS03500
gene id: 1547283:A9C19_RS03500
uniprot id: A0A1L3MNJ3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1547283:A9C19 RS17450
gene id: 1547283:A9C19_RS17450
uniprot id: A0A1L3MVG1
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

1547283:A9C19 RS19710
gene id: 1547283:A9C19_RS19710
uniprot id: A0A1L3MWH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1547283:A9C19 RS02175
gene id: 1547283:A9C19_RS02175
uniprot id: A0A1L3MMR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1547283:A9C19 RS05495
gene id: 1547283:A9C19_RS05495
uniprot id: A0A1L3MPQ4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

1547283:A9C19 RS06850
gene id: 1547283:A9C19_RS06850
uniprot id: A0A1L3MQ48
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1547283:A9C19 RS16475
gene id: 1547283:A9C19_RS16475
uniprot id: A0A1L3MV02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some proteins.

1547283:A9C19 RS07430
gene id: 1547283:A9C19_RS07430
uniprot id: A0A1L3MQI6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1547283:A9C19 RS15545
gene id: 1547283:A9C19_RS15545
uniprot id: A0A1L3MUG8
names: Subcellular Location Annotation
messages: Cell membrane

1547283:A9C19 RS20715
gene id: 1547283:A9C19_RS20715
uniprot id: A0A1L3MWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1547283:A9C19 RS03015
gene id: 1547283:A9C19_RS03015
uniprot id: A0A1L3MN99
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS19565
gene id: 1547283:A9C19_RS19565
uniprot id: A0A1L3MWD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1547283:A9C19 RS20225
gene id: 1547283:A9C19_RS20225
uniprot id: A0A1L3MWN6
names: Similarity
messages: Belongs to the DCK/DGK family.

1547283:A9C19 RS06505
gene id: 1547283:A9C19_RS06505
uniprot id: A0A1L3MPX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ComGC family.
messages: Cell membrane
messages: Homodimer.
messages: Required for transformation and DNA binding.

1547283:A9C19 RS06620
gene id: 1547283:A9C19_RS06620
uniprot id: A0A1L3MPY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1547283:A9C19 RS10445
gene id: 1547283:A9C19_RS10445
uniprot id: A0A1L3MRY4
names: Similarity
messages: Belongs to the HesB/IscA family.

1547283:A9C19 RS08390
gene id: 1547283:A9C19_RS08390
uniprot id: A0A1L3MR58
names: Similarity
messages: Belongs to the peptidase S41A family.

1547283:A9C19 RS15570
gene id: 1547283:A9C19_RS15570
uniprot id: A0A1L3MUH2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1547283:A9C19 RS05805
gene id: 1547283:A9C19_RS05805
uniprot id: A0A1L3MPK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS08830
gene id: 1547283:A9C19_RS08830
uniprot id: A0A1L3MR63
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1547283:A9C19 RS12280
gene id: 1547283:A9C19_RS12280
uniprot id: A0A1L3MSZ8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1547283:A9C19 RS08985
gene id: 1547283:A9C19_RS08985
uniprot id: A0A1L3MR74
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS14540
gene id: 1547283:A9C19_RS14540
uniprot id: A0A1L3MTY9
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1547283:A9C19 RS15640
gene id: 1547283:A9C19_RS15640
uniprot id: A0A1L3MUL0
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1547283:A9C19 RS17445
gene id: 1547283:A9C19_RS17445
uniprot id: A0A1L3MVD6
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1547283:A9C19 RS19585
gene id: 1547283:A9C19_RS19585
uniprot id: A0A1L3MWK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1547283:A9C19 RS20720
gene id: 1547283:A9C19_RS20720
uniprot id: A0A1L3MWW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1547283:A9C19 RS14440
gene id: 1547283:A9C19_RS14440
uniprot id: A0A1L3MTW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1547283:A9C19 RS07215
gene id: 1547283:A9C19_RS07215
uniprot id: A0A1L3MXC8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1547283:A9C19 RS05400
gene id: 1547283:A9C19_RS05400
uniprot id: A0A1L3MPB8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1547283:A9C19 RS04480
gene id: 1547283:A9C19_RS04480
uniprot id: A0A1L3MNU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS06035
gene id: 1547283:A9C19_RS06035
uniprot id: A0A1L3MPS3
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1547283:A9C19 RS00450
gene id: 1547283:A9C19_RS00450
uniprot id: A0A1L3MLV6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1547283:A9C19 RS19440
gene id: 1547283:A9C19_RS19440
uniprot id: A0A1L3MWB2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1547283:A9C19 RS19445
gene id: 1547283:A9C19_RS19445
uniprot id: A0A1L3MWC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1547283:A9C19 RS15065
gene id: 1547283:A9C19_RS15065
uniprot id: A0A1L3MXR9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1547283:A9C19 RS17600
gene id: 1547283:A9C19_RS17600
uniprot id: A0A1L3MVJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1547283:A9C19 RS20455
gene id: 1547283:A9C19_RS20455
uniprot id: A0A1L3MWS9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1547283:A9C19 RS05670
gene id: 1547283:A9C19_RS05670
uniprot id: A0A1L3MPH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1547283:A9C19 RS07675
gene id: 1547283:A9C19_RS07675
uniprot id: A0A1L3MQI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1547283:A9C19 RS16430
gene id: 1547283:A9C19_RS16430
uniprot id: A0A1L3MUZ1
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS17105
gene id: 1547283:A9C19_RS17105
uniprot id: A0A1L3MV78
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspK family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

1547283:A9C19 RS19610
gene id: 1547283:A9C19_RS19610
uniprot id: A0A1L3MWF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1547283:A9C19 RS19550
gene id: 1547283:A9C19_RS19550
uniprot id: A0A1L3MWE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1547283:A9C19 RS03475
gene id: 1547283:A9C19_RS03475
uniprot id: A0A1L3MNH5
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS11870
gene id: 1547283:A9C19_RS11870
uniprot id: A0A1L3MSP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1547283:A9C19 RS05145
gene id: 1547283:A9C19_RS05145
uniprot id: A0A1L3MP88
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1547283:A9C19 RS05705
gene id: 1547283:A9C19_RS05705
uniprot id: A0A1L3MPL8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1547283:A9C19 RS14030
gene id: 1547283:A9C19_RS14030
uniprot id: A0A1L3MTQ6
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS12660
gene id: 1547283:A9C19_RS12660
uniprot id: A0A1L3MT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1547283:A9C19 RS18410
gene id: 1547283:A9C19_RS18410
uniprot id: A0A1L3MVW5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1547283:A9C19 RS12260
gene id: 1547283:A9C19_RS12260
uniprot id: A0A1L3MSU7
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1547283:A9C19 RS05905
gene id: 1547283:A9C19_RS05905
uniprot id: A0A1L3MPL2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1547283:A9C19 RS20465
gene id: 1547283:A9C19_RS20465
uniprot id: A0A1L3MWS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1547283:A9C19 RS15800
gene id: 1547283:A9C19_RS15800
uniprot id: A0A1L3MNI1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1547283:A9C19 RS16990
gene id: 1547283:A9C19_RS16990
uniprot id: A0A1L3MV76
names: Similarity
messages: Belongs to the peptidase M29 family.

1547283:A9C19 RS08355
gene id: 1547283:A9C19_RS08355
uniprot id: A0A1L3MQW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1547283:A9C19 RS05725
gene id: 1547283:A9C19_RS05725
uniprot id: A0A1L3MPI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1547283:A9C19 RS02280
gene id: 1547283:A9C19_RS02280
uniprot id: A0A1L3MMW1
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1547283:A9C19 RS06280
gene id: 1547283:A9C19_RS06280
uniprot id: A0A1L3MPT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1547283:A9C19 RS10755
gene id: 1547283:A9C19_RS10755
uniprot id: A0A1L3MS51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1547283:A9C19 RS13795
gene id: 1547283:A9C19_RS13795
uniprot id: A0A1L3MTN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1547283:A9C19 RS06320
gene id: 1547283:A9C19_RS06320
uniprot id: A0A1L3MPV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1547283:A9C19 RS20410
gene id: 1547283:A9C19_RS20410
uniprot id: A0A1L3MWS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1547283:A9C19 RS07340
gene id: 1547283:A9C19_RS07340
uniprot id: A0A1L3MQC3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1547283:A9C19 RS20110
gene id: 1547283:A9C19_RS20110
uniprot id: A0A1L3MWM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

1547283:A9C19 RS04595
gene id: 1547283:A9C19_RS04595
uniprot id: A0A1L3MNW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1547283:A9C19 RS12030
gene id: 1547283:A9C19_RS12030
uniprot id: A0A1L3MSQ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS14195
gene id: 1547283:A9C19_RS14195
uniprot id: A0A1L3MTT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS19510
gene id: 1547283:A9C19_RS19510
uniprot id: A0A1L3MWD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1547283:A9C19 RS19505
gene id: 1547283:A9C19_RS19505
uniprot id: A0A1L3MWD4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1547283:A9C19 RS03695
gene id: 1547283:A9C19_RS03695
uniprot id: A0A1L3MNJ9
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS10230
gene id: 1547283:A9C19_RS10230
uniprot id: A0A1L3MXI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1547283:A9C19 RS11430
gene id: 1547283:A9C19_RS11430
uniprot id: A0A1L3MSL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1547283:A9C19 RS02195
gene id: 1547283:A9C19_RS02195
uniprot id: A0A1L3MMW9
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1547283:A9C19 RS11740
gene id: 1547283:A9C19_RS11740
uniprot id: A0A1L3MXQ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS01855
gene id: 1547283:A9C19_RS01855
uniprot id: A0A1L3MMK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1547283:A9C19 RS01790
gene id: 1547283:A9C19_RS01790
uniprot id: A0A1L3MMK2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1547283:A9C19 RS03795
gene id: 1547283:A9C19_RS03795
uniprot id: A0A1L3MNX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07765
gene id: 1547283:A9C19_RS07765
uniprot id: A0A1L3MQK1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1547283:A9C19 RS18450
gene id: 1547283:A9C19_RS18450
uniprot id: A0A1L3MVY5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1547283:A9C19 RS10895
gene id: 1547283:A9C19_RS10895
uniprot id: A0A1L3MS54
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1547283:A9C19 RS19715
gene id: 1547283:A9C19_RS19715
uniprot id: A0A1L3MWH5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1547283:A9C19 RS20775
gene id: 1547283:A9C19_RS20775
uniprot id: A0A1L3MWX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1547283:A9C19 RS18315
gene id: 1547283:A9C19_RS18315
uniprot id: A0A1L3MVU9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1547283:A9C19 RS11660
gene id: 1547283:A9C19_RS11660
uniprot id: A0A1L3MSK6
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS11445
gene id: 1547283:A9C19_RS11445
uniprot id: A0A1L3MXI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1547283:A9C19 RS11220
gene id: 1547283:A9C19_RS11220
uniprot id: A0A1L3MSC7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1547283:A9C19 RS12880
gene id: 1547283:A9C19_RS12880
uniprot id: A0A1L3MT68
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1547283:A9C19 RS03720
gene id: 1547283:A9C19_RS03720
uniprot id: A0A1L3MNJ6
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS04940
gene id: 1547283:A9C19_RS04940
uniprot id: A0A1L3MP43
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1547283:A9C19 RS14555
gene id: 1547283:A9C19_RS14555
uniprot id: A0A1L3MU40
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1547283:A9C19 RS02995
gene id: 1547283:A9C19_RS02995
uniprot id: A0A1L3MN56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS00785
gene id: 1547283:A9C19_RS00785
uniprot id: A0A1L3MM58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1547283:A9C19 RS06730
gene id: 1547283:A9C19_RS06730
uniprot id: A0A1L3MQ20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1547283:A9C19 RS08185
gene id: 1547283:A9C19_RS08185
uniprot id: A0A1L3MQR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1547283:A9C19 RS11525
gene id: 1547283:A9C19_RS11525
uniprot id: A0A1L3MSI6
names: Similarity
messages: Belongs to the asp23 family.

1547283:A9C19 RS20335
gene id: 1547283:A9C19_RS20335
uniprot id: A0A1L3MWR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1547283:A9C19 RS00140
gene id: 1547283:A9C19_RS00140
uniprot id: A0A1L3MM03
names: Similarity
messages: Belongs to the EamA transporter family.

1547283:A9C19 RS04230
gene id: 1547283:A9C19_RS04230
uniprot id: A0A1L3MNR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS11765
gene id: 1547283:A9C19_RS11765
uniprot id: A0A1L3MSL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1547283:A9C19 RS08005
gene id: 1547283:A9C19_RS08005
uniprot id: A0A1L3MQQ1
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS11085
gene id: 1547283:A9C19_RS11085
uniprot id: A0A1L3MSA5
names: Similarity
messages: Belongs to the ribF family.

1547283:A9C19 RS16130
gene id: 1547283:A9C19_RS16130
uniprot id: A0A1L3MUT6
names: Similarity
messages: Belongs to the UPF0145 family.

1547283:A9C19 RS14305
gene id: 1547283:A9C19_RS14305
uniprot id: A0A1L3MTU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS19255
gene id: 1547283:A9C19_RS19255
uniprot id: A0A1L3MW90
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1547283:A9C19 RS11880
gene id: 1547283:A9C19_RS11880
uniprot id: A0A1L3MXL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1547283:A9C19 RS05315
gene id: 1547283:A9C19_RS05315
uniprot id: A0A1L3MPM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1547283:A9C19 RS07100
gene id: 1547283:A9C19_RS07100
uniprot id: A0A1L3MQ89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1547283:A9C19 RS02600
gene id: 1547283:A9C19_RS02600
uniprot id: A0A1L3MN06
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS11045
gene id: 1547283:A9C19_RS11045
uniprot id: A0A1L3MS89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS02150
gene id: 1547283:A9C19_RS02150
uniprot id: A0A1L3MMS1
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PpaX family.
messages: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool.

1547283:A9C19 RS16985
gene id: 1547283:A9C19_RS16985
uniprot id: A0A1L3MV66
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1547283:A9C19 RS15415
gene id: 1547283:A9C19_RS15415
uniprot id: A0A1L3MUE8
names: Similarity
messages: Belongs to the asparagine synthetase family.

1547283:A9C19 RS20050
gene id: 1547283:A9C19_RS20050
uniprot id: A0A1L3MWK5
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1547283:A9C19 RS12155
gene id: 1547283:A9C19_RS12155
uniprot id: A0A1L3MSS4
names: Similarity
messages: Belongs to the UPF0223 family.

1547283:A9C19 RS08225
gene id: 1547283:A9C19_RS08225
uniprot id: A0A1L3MQU6
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS11815
gene id: 1547283:A9C19_RS11815
uniprot id: A0A1L3MSM9
names: Similarity
messages: Belongs to the UPF0749 family.

1547283:A9C19 RS20220
gene id: 1547283:A9C19_RS20220
uniprot id: A0A1L3MWQ8
names: Similarity
messages: Belongs to the DCK/DGK family.

1547283:A9C19 RS14960
gene id: 1547283:A9C19_RS14960
uniprot id: A0A1L3MU77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS03575
gene id: 1547283:A9C19_RS03575
uniprot id: A0A1L3MNI3
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS06250
gene id: 1547283:A9C19_RS06250
uniprot id: A0A1L3MQ21
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1547283:A9C19 RS11600
gene id: 1547283:A9C19_RS11600
uniprot id: A0A1L3MXK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1547283:A9C19 RS05740
gene id: 1547283:A9C19_RS05740
uniprot id: A0A1L3MPK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS15395
gene id: 1547283:A9C19_RS15395
uniprot id: A0A1L3MUF5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1547283:A9C19 RS01480
gene id: 1547283:A9C19_RS01480
uniprot id: A0A1L3MMD2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1547283:A9C19 RS10545
gene id: 1547283:A9C19_RS10545
uniprot id: A0A1L3MS01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1547283:A9C19 RS09315
gene id: 1547283:A9C19_RS09315
uniprot id: A0A1L3MRE7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1547283:A9C19 RS12220
gene id: 1547283:A9C19_RS12220
uniprot id: A0A1L3MSY8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1547283:A9C19 RS06120
gene id: 1547283:A9C19_RS06120
uniprot id: A0A1L3MPS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1547283:A9C19 RS11080
gene id: 1547283:A9C19_RS11080
uniprot id: A0A1L3MS80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1547283:A9C19 RS01685
gene id: 1547283:A9C19_RS01685
uniprot id: A0A1L3MMJ9
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

1547283:A9C19 RS20190
gene id: 1547283:A9C19_RS20190
uniprot id: A0A1L3MXX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1547283:A9C19 RS07250
gene id: 1547283:A9C19_RS07250
uniprot id: A0A1L3MQA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1547283:A9C19 RS05040
gene id: 1547283:A9C19_RS05040
uniprot id: A0A1L3MPH7
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

1547283:A9C19 RS18865
gene id: 1547283:A9C19_RS18865
uniprot id: A0A1L3MW55
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1547283:A9C19 RS16400
gene id: 1547283:A9C19_RS16400
uniprot id: A0A1L3MV39
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS14255
gene id: 1547283:A9C19_RS14255
uniprot id: A0A1L3MTU3
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS13045
gene id: 1547283:A9C19_RS13045
uniprot id: A0A1L3MTE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Homodimer.

1547283:A9C19 RS19640
gene id: 1547283:A9C19_RS19640
uniprot id: A0A1L3MWF2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.

1547283:A9C19 RS11745
gene id: 1547283:A9C19_RS11745
uniprot id: A0A1L3MSK5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1547283:A9C19 RS16590
gene id: 1547283:A9C19_RS16590
uniprot id: A0A1L3MV27
names: Similarity
messages: Belongs to the UPF0229 family.

1547283:A9C19 RS11630
gene id: 1547283:A9C19_RS11630
uniprot id: A0A1L3MSP3
names: Similarity
messages: Belongs to the EamA transporter family.

1547283:A9C19 RS00770
gene id: 1547283:A9C19_RS00770
uniprot id: A0A1L3MM15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1547283:A9C19 RS11160
gene id: 1547283:A9C19_RS11160
uniprot id: A0A1L3MSA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1547283:A9C19 RS00815
gene id: 1547283:A9C19_RS00815
uniprot id: A0A1L3MM50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS00685
gene id: 1547283:A9C19_RS00685
uniprot id: A0A1L3MM05
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1547283:A9C19 RS02830
gene id: 1547283:A9C19_RS02830
uniprot id: A0A1L3MNC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1547283:A9C19 RS12040
gene id: 1547283:A9C19_RS12040
uniprot id: A0A1L3MSR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS02295
gene id: 1547283:A9C19_RS02295
uniprot id: A0A1L3MMT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1547283:A9C19 RS07030
gene id: 1547283:A9C19_RS07030
uniprot id: A0A1L3MQG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1547283:A9C19 RS03270
gene id: 1547283:A9C19_RS03270
uniprot id: A0A1L3MNB1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1547283:A9C19 RS04110
gene id: 1547283:A9C19_RS04110
uniprot id: A0A1L3MNP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

1547283:A9C19 RS11270
gene id: 1547283:A9C19_RS11270
uniprot id: A0A1L3MSD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1547283:A9C19 RS03595
gene id: 1547283:A9C19_RS03595
uniprot id: A0A1L3MNI1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1547283:A9C19 RS19740
gene id: 1547283:A9C19_RS19740
uniprot id: A0A1L3MWM5
names: Similarity
messages: Belongs to the ycf81 family.

1547283:A9C19 RS20315
gene id: 1547283:A9C19_RS20315
uniprot id: A0A1L3MXX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1547283:A9C19 RS07790
gene id: 1547283:A9C19_RS07790
uniprot id: A0A1L3MQK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1547283:A9C19 RS12975
gene id: 1547283:A9C19_RS12975
uniprot id: A0A1L3MTD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1547283:A9C19 RS09050
gene id: 1547283:A9C19_RS09050
uniprot id: A0A1L3MR57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1547283:A9C19 RS09330
gene id: 1547283:A9C19_RS09330
uniprot id: A0A1L3MRE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS14560
gene id: 1547283:A9C19_RS14560
uniprot id: A0A1L3MTZ5
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS20020
gene id: 1547283:A9C19_RS20020
uniprot id: A0A1L3MWL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1547283:A9C19 RS12385
gene id: 1547283:A9C19_RS12385
uniprot id: A0A1L3MT20
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1547283:A9C19 RS05500
gene id: 1547283:A9C19_RS05500
uniprot id: A0A1L3MPD5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

1547283:A9C19 RS15645
gene id: 1547283:A9C19_RS15645
uniprot id: A0A1L3MUH5
names: Similarity
messages: Belongs to the peptidase S66 family.

1547283:A9C19 RS20045
gene id: 1547283:A9C19_RS20045
uniprot id: A0A1L3MWR5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1547283:A9C19 RS19450
gene id: 1547283:A9C19_RS19450
uniprot id: A0A1L3MWC1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS00220
gene id: 1547283:A9C19_RS00220
uniprot id: A0A1L3MLU4
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS03910
gene id: 1547283:A9C19_RS03910
uniprot id: A0A1L3MP25
names: Similarity
messages: Belongs to the EamA transporter family.

1547283:A9C19 RS05060
gene id: 1547283:A9C19_RS05060
uniprot id: A0A1L3MP62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1547283:A9C19 RS13800
gene id: 1547283:A9C19_RS13800
uniprot id: A0A1L3MTM8
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS19630
gene id: 1547283:A9C19_RS19630
uniprot id: A0A1L3MWE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1547283:A9C19 RS06450
gene id: 1547283:A9C19_RS06450
uniprot id: A0A1L3MPW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07410
gene id: 1547283:A9C19_RS07410
uniprot id: A0A1L3MQD9
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS09500
gene id: 1547283:A9C19_RS09500
uniprot id: A0A1L3MRG4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1547283:A9C19 RS05845
gene id: 1547283:A9C19_RS05845
uniprot id: A0A1L3MPJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS07735
gene id: 1547283:A9C19_RS07735
uniprot id: A0A1L3MQJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Component of the menaquinol:cytochrome c reductase complex.
messages: Membrane
messages: The main subunits of the menaquinol:cytochrome c complex are a Rieske-type iron-sulfur protein (QcrA), a cytochrome b (QcrB) and a cytochrome c (QcrC).

1547283:A9C19 RS05360
gene id: 1547283:A9C19_RS05360
uniprot id: A0A1L3MXC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1547283:A9C19 RS11435
gene id: 1547283:A9C19_RS11435
uniprot id: A0A1L3MSF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1547283:A9C19 RS05430
gene id: 1547283:A9C19_RS05430
uniprot id: A0A1L3MPC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1547283:A9C19 RS06150
gene id: 1547283:A9C19_RS06150
uniprot id: A0A1L3MPR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1547283:A9C19 RS16315
gene id: 1547283:A9C19_RS16315
uniprot id: A0A1L3MUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1547283:A9C19 RS00110
gene id: 1547283:A9C19_RS00110
uniprot id: A0A1L3MLR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

1547283:A9C19 RS12930
gene id: 1547283:A9C19_RS12930
uniprot id: A0A1L3MT71
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1547283:A9C19 RS14020
gene id: 1547283:A9C19_RS14020
uniprot id: A0A1L3MTS9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS14135
gene id: 1547283:A9C19_RS14135
uniprot id: A0A1L3MTR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1547283:A9C19 RS11850
gene id: 1547283:A9C19_RS11850
uniprot id: A0A1L3MSM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS17355
gene id: 1547283:A9C19_RS17355
uniprot id: A0A1L3MVC4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1547283:A9C19 RS02405
gene id: 1547283:A9C19_RS02405
uniprot id: A0A1L3MMV5
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS11580
gene id: 1547283:A9C19_RS11580
uniprot id: A0A1L3MSJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1547283:A9C19 RS19055
gene id: 1547283:A9C19_RS19055
uniprot id: A0A1L3MW73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

1547283:A9C19 RS13085
gene id: 1547283:A9C19_RS13085
uniprot id: A0A1L3MT96
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07120
gene id: 1547283:A9C19_RS07120
uniprot id: A0A1L3MQ87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
messages: Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes.
messages: Homotetramer.

1547283:A9C19 RS12695
gene id: 1547283:A9C19_RS12695
uniprot id: A0A1L3MT29
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1547283:A9C19 RS04585
gene id: 1547283:A9C19_RS04585
uniprot id: A0A1L3MNY2
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1547283:A9C19 RS20985
gene id: 1547283:A9C19_RS20985
uniprot id: A0A1L3MLR7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1547283:A9C19 RS15120
gene id: 1547283:A9C19_RS15120
uniprot id: A0A1L3MU92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS11785
gene id: 1547283:A9C19_RS11785
uniprot id: A0A1L3MSM7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1547283:A9C19 RS12375
gene id: 1547283:A9C19_RS12375
uniprot id: A0A1L3MSW5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1547283:A9C19 RS09285
gene id: 1547283:A9C19_RS09285
uniprot id: A0A1L3MRB5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1547283:A9C19 RS00270
gene id: 1547283:A9C19_RS00270
uniprot id: A0A1L3MLU5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS02285
gene id: 1547283:A9C19_RS02285
uniprot id: A0A1L3MMU0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1547283:A9C19 RS11150
gene id: 1547283:A9C19_RS11150
uniprot id: A0A1L3MSA9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS12875
gene id: 1547283:A9C19_RS12875
uniprot id: A0A1L3MT62
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS13190
gene id: 1547283:A9C19_RS13190
uniprot id: A0A1L3MTC7
names: Similarity
messages: Belongs to the TPP enzyme family.

1547283:A9C19 RS00150
gene id: 1547283:A9C19_RS00150
uniprot id: A0A1L3MLS3
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1547283:A9C19 RS00765
gene id: 1547283:A9C19_RS00765
uniprot id: A0A1L3MM40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1547283:A9C19 RS11595
gene id: 1547283:A9C19_RS11595
uniprot id: A0A1L3MSJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1547283:A9C19 RS20035
gene id: 1547283:A9C19_RS20035
uniprot id: A0A1L3MWM7
names: Similarity
messages: Belongs to the RutC family.

1547283:A9C19 RS07830
gene id: 1547283:A9C19_RS07830
uniprot id: A0A1L3MQL8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1547283:A9C19 RS17995
gene id: 1547283:A9C19_RS17995
uniprot id: A0A1L3MVW6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1547283:A9C19 RS05310
gene id: 1547283:A9C19_RS05310
uniprot id: A0A1L3MPA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1547283:A9C19 RS19590
gene id: 1547283:A9C19_RS19590
uniprot id: A0A1L3MWE3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1547283:A9C19 RS08180
gene id: 1547283:A9C19_RS08180
uniprot id: A0A1L3MQR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1547283:A9C19 RS07715
gene id: 1547283:A9C19_RS07715
uniprot id: A0A1L3MQI9
names: Similarity
messages: Belongs to the UPF0302 family.

1547283:A9C19 RS08960
gene id: 1547283:A9C19_RS08960
uniprot id: A0A1L3MRE4
names: Similarity
messages: Belongs to the EamA transporter family.

1547283:A9C19 RS04670
gene id: 1547283:A9C19_RS04670
uniprot id: A0A1L3MNZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1547283:A9C19 RS11930
gene id: 1547283:A9C19_RS11930
uniprot id: A0A1L3MSU1
names: Similarity
messages: Belongs to the peptidase S16 family.

1547283:A9C19 RS00655
gene id: 1547283:A9C19_RS00655
uniprot id: A0A1L3MM18
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1547283:A9C19 RS19650
gene id: 1547283:A9C19_RS19650
uniprot id: A0A1L3MWG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1547283:A9C19 RS15360
gene id: 1547283:A9C19_RS15360
uniprot id: A0A1L3MUE6
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS10310
gene id: 1547283:A9C19_RS10310
uniprot id: A0A1L3MRW3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1547283:A9C19 RS11275
gene id: 1547283:A9C19_RS11275
uniprot id: A0A1L3MSH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell membrane
messages: Membrane
messages: One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation.

1547283:A9C19 RS00930
gene id: 1547283:A9C19_RS00930
uniprot id: A0A1L3MM44
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS12835
gene id: 1547283:A9C19_RS12835
uniprot id: A0A1L3MT64
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1547283:A9C19 RS14710
gene id: 1547283:A9C19_RS14710
uniprot id: A0A1L3MU23
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS20345
gene id: 1547283:A9C19_RS20345
uniprot id: A0A1L3MWQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1547283:A9C19 RS11840
gene id: 1547283:A9C19_RS11840
uniprot id: A0A1L3MSN9
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS12080
gene id: 1547283:A9C19_RS12080
uniprot id: A0A1L3MSS8
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS11790
gene id: 1547283:A9C19_RS11790
uniprot id: A0A1L3MSS3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1547283:A9C19 RS05085
gene id: 1547283:A9C19_RS05085
uniprot id: A0A1L3MP65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1547283:A9C19 RS04645
gene id: 1547283:A9C19_RS04645
uniprot id: A0A1L3MNX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Monomer.
messages: Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue.

1547283:A9C19 RS02320
gene id: 1547283:A9C19_RS02320
uniprot id: A0A1L3MMU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1547283:A9C19 RS14480
gene id: 1547283:A9C19_RS14480
uniprot id: A0A1L3MTY0
names: Similarity
messages: Belongs to the KdgT transporter family.

1547283:A9C19 RS08330
gene id: 1547283:A9C19_RS08330
uniprot id: A0A1L3MXE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

1547283:A9C19 RS06960
gene id: 1547283:A9C19_RS06960
uniprot id: A0A1L3MQ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS19990
gene id: 1547283:A9C19_RS19990
uniprot id: A0A1L3MWK0
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS17090
gene id: 1547283:A9C19_RS17090
uniprot id: A0A1L3MV88
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1547283:A9C19 RS14890
gene id: 1547283:A9C19_RS14890
uniprot id: A0A1L3MUB0
names: Similarity
messages: Belongs to the SCO1/2 family.

1547283:A9C19 RS02135
gene id: 1547283:A9C19_RS02135
uniprot id: A0A1L3MMQ8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1547283:A9C19 RS11355
gene id: 1547283:A9C19_RS11355
uniprot id: A0A1L3MSF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

1547283:A9C19 RS09380
gene id: 1547283:A9C19_RS09380
uniprot id: A0A1L3MRA3
names: Subcellular Location Annotation
messages: Cell membrane

1547283:A9C19 RS18845
gene id: 1547283:A9C19_RS18845
uniprot id: A0A1L3MW39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1547283:A9C19 RS09015
gene id: 1547283:A9C19_RS09015
uniprot id: A0A1L3MR73
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1547283:A9C19 RS06965
gene id: 1547283:A9C19_RS06965
uniprot id: A0A1L3MQA1
names: Subcellular Location Annotation
messages: Cell membrane

1547283:A9C19 RS20630
gene id: 1547283:A9C19_RS20630
uniprot id: A0A1L3MWU6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS08090
gene id: 1547283:A9C19_RS08090
uniprot id: A0A1L3MQW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. UgtP subfamily.
messages: Cell membrane
messages: Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).

1547283:A9C19 RS05770
gene id: 1547283:A9C19_RS05770
uniprot id: A0A1L3MPU8
names: Similarity
messages: Belongs to the RecJ family.

1547283:A9C19 RS19580
gene id: 1547283:A9C19_RS19580
uniprot id: A0A1L3MWD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1547283:A9C19 RS16570
gene id: 1547283:A9C19_RS16570
uniprot id: A0A1L3MV11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS15245
gene id: 1547283:A9C19_RS15245
uniprot id: A0A1L3MUD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

1547283:A9C19 RS18385
gene id: 1547283:A9C19_RS18385
uniprot id: A0A1L3MVY0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1547283:A9C19 RS18120
gene id: 1547283:A9C19_RS18120
uniprot id: A0A1L3MVT6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1547283:A9C19 RS13805
gene id: 1547283:A9C19_RS13805
uniprot id: A0A1L3MTR6
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1547283:A9C19 RS07245
gene id: 1547283:A9C19_RS07245
uniprot id: A0A1L3MQA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1547283:A9C19 RS04070
gene id: 1547283:A9C19_RS04070
uniprot id: A0A1L3MNN3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1547283:A9C19 RS20195
gene id: 1547283:A9C19_RS20195
uniprot id: A0A1L3MWP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1547283:A9C19 RS00795
gene id: 1547283:A9C19_RS00795
uniprot id: A0A1L3MM28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1547283:A9C19 RS11340
gene id: 1547283:A9C19_RS11340
uniprot id: A0A1L3MSD3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1547283:A9C19 RS04185
gene id: 1547283:A9C19_RS04185
uniprot id: A0A1L3MNQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1547283:A9C19 RS04420
gene id: 1547283:A9C19_RS04420
uniprot id: A0A1L3MNT5
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS11960
gene id: 1547283:A9C19_RS11960
uniprot id: A0A1L3MSR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0298 family.
messages: Cytoplasm

1547283:A9C19 RS06090
gene id: 1547283:A9C19_RS06090
uniprot id: A0A1L3MPP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1547283:A9C19 RS10660
gene id: 1547283:A9C19_RS10660
uniprot id: A0A1L3MS36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS02445
gene id: 1547283:A9C19_RS02445
uniprot id: A0A1L3MMX5
names: Similarity
messages: Belongs to the EamA transporter family.

1547283:A9C19 RS06015
gene id: 1547283:A9C19_RS06015
uniprot id: A0A1L3MPQ2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1547283:A9C19 RS00035
gene id: 1547283:A9C19_RS00035
uniprot id: A0A1L3MLP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EssB family.
messages: Membrane

1547283:A9C19 RS19085
gene id: 1547283:A9C19_RS19085
uniprot id: A0A1L3MW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1547283:A9C19 RS10245
gene id: 1547283:A9C19_RS10245
uniprot id: A0A1L3MRW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1547283:A9C19 RS15185
gene id: 1547283:A9C19_RS15185
uniprot id: A0A1L3MUC7
names: Similarity
messages: Belongs to the UPF0736 family.

1547283:A9C19 RS09025
gene id: 1547283:A9C19_RS09025
uniprot id: A0A1L3MR49
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1547283:A9C19 RS07315
gene id: 1547283:A9C19_RS07315
uniprot id: A0A1L3MQD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS01450
gene id: 1547283:A9C19_RS01450
uniprot id: A0A1L3MME0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1547283:A9C19 RS06105
gene id: 1547283:A9C19_RS06105
uniprot id: A0A1L3MPQ9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1547283:A9C19 RS15425
gene id: 1547283:A9C19_RS15425
uniprot id: A0A1L3MUG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0344 family.
messages: Cell membrane

1547283:A9C19 RS07680
gene id: 1547283:A9C19_RS07680
uniprot id: A0A1L3MQI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1547283:A9C19 RS20835
gene id: 1547283:A9C19_RS20835
uniprot id: A0A1L3MWZ2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1547283:A9C19 RS16800
gene id: 1547283:A9C19_RS16800
uniprot id: A0A1L3MV53
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS11735
gene id: 1547283:A9C19_RS11735
uniprot id: A0A1L3MSR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1547283:A9C19 RS00250
gene id: 1547283:A9C19_RS00250
uniprot id: A0A1L3MLT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds a copper B center.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Heme A3.
messages: Membrane

1547283:A9C19 RS11565
gene id: 1547283:A9C19_RS11565
uniprot id: A0A1L3MSH3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1547283:A9C19 RS02820
gene id: 1547283:A9C19_RS02820
uniprot id: A0A1L3MN81
names: Similarity
messages: Belongs to the peptidase S11 family.

1547283:A9C19 RS00790
gene id: 1547283:A9C19_RS00790
uniprot id: A0A1L3MM67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1547283:A9C19 RS01970
gene id: 1547283:A9C19_RS01970
uniprot id: A0A1L3MMM4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1547283:A9C19 RS05665
gene id: 1547283:A9C19_RS05665
uniprot id: A0A1L3MPG5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1547283:A9C19 RS10325
gene id: 1547283:A9C19_RS10325
uniprot id: A0A1L3MRW8
names: Similarity
messages: Belongs to the nitroreductase family.

1547283:A9C19 RS08875
gene id: 1547283:A9C19_RS08875
uniprot id: A0A1L3MR56
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS17815
gene id: 1547283:A9C19_RS17815
uniprot id: A0A1L3MVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1547283:A9C19 RS10700
gene id: 1547283:A9C19_RS10700
uniprot id: A0A1L3MS96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1547283:A9C19 RS07255
gene id: 1547283:A9C19_RS07255
uniprot id: A0A1L3MQB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1547283:A9C19 RS09415
gene id: 1547283:A9C19_RS09415
uniprot id: A0A1L3MRH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS20425
gene id: 1547283:A9C19_RS20425
uniprot id: A0A1L3MWR6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1547283:A9C19 RS11395
gene id: 1547283:A9C19_RS11395
uniprot id: A0A1L3MSG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1547283:A9C19 RS00415
gene id: 1547283:A9C19_RS00415
uniprot id: A0A1L3MLW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07750
gene id: 1547283:A9C19_RS07750
uniprot id: A0A1L3MQP3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS11495
gene id: 1547283:A9C19_RS11495
uniprot id: A0A1L3MXI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1547283:A9C19 RS12710
gene id: 1547283:A9C19_RS12710
uniprot id: A0A1L3MT75
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1547283:A9C19 RS00460
gene id: 1547283:A9C19_RS00460
uniprot id: A0A1L3MM02
names: Function
names: Similarity
messages: Belongs to the uve1/UvsE family.
messages: Component in a DNA repair pathway. Removal of UV LIGHT damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion.
messages: Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion.

1547283:A9C19 RS00645
gene id: 1547283:A9C19_RS00645
uniprot id: A0A1L3MM20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1547283:A9C19 RS13660
gene id: 1547283:A9C19_RS13660
uniprot id: A0A1L3MTQ1
names: Subcellular Location Annotation
messages: Cell membrane

1547283:A9C19 RS14640
gene id: 1547283:A9C19_RS14640
uniprot id: A0A1L3MU13
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS02425
gene id: 1547283:A9C19_RS02425
uniprot id: A0A1L3MN48
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1547283:A9C19 RS08095
gene id: 1547283:A9C19_RS08095
uniprot id: A0A1L3MQS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1547283:A9C19 RS01745
gene id: 1547283:A9C19_RS01745
uniprot id: A0A1L3MMK5
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS16685
gene id: 1547283:A9C19_RS16685
uniprot id: A0A1L3MV37
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1547283:A9C19 RS04935
gene id: 1547283:A9C19_RS04935
uniprot id: A0A1L3MP42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1547283:A9C19 RS02580
gene id: 1547283:A9C19_RS02580
uniprot id: A0A1L3MN80
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1547283:A9C19 RS17625
gene id: 1547283:A9C19_RS17625
uniprot id: A0A1L3MVH2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1547283:A9C19 RS02300
gene id: 1547283:A9C19_RS02300
uniprot id: A0A1L3MMX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1547283:A9C19 RS03640
gene id: 1547283:A9C19_RS03640
uniprot id: A0A1L3MNJ2
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS11820
gene id: 1547283:A9C19_RS11820
uniprot id: A0A1L3MXJ5
names: Similarity
messages: Belongs to the UPF0749 family.

1547283:A9C19 RS07900
gene id: 1547283:A9C19_RS07900
uniprot id: A0A1L3MQM2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1547283:A9C19 RS09035
gene id: 1547283:A9C19_RS09035
uniprot id: A0A1L3MR83
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1547283:A9C19 RS05955
gene id: 1547283:A9C19_RS05955
uniprot id: A0A1L3MPM2
names: Similarity
messages: Belongs to the transpeptidase family.

1547283:A9C19 RS06820
gene id: 1547283:A9C19_RS06820
uniprot id: A0A1L3MQ50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1547283:A9C19 RS02010
gene id: 1547283:A9C19_RS02010
uniprot id: A0A1L3MMP0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1547283:A9C19 RS19240
gene id: 1547283:A9C19_RS19240
uniprot id: A0A1L3MW87
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1547283:A9C19 RS16805
gene id: 1547283:A9C19_RS16805
uniprot id: A0A1L3MV60
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS14895
gene id: 1547283:A9C19_RS14895
uniprot id: A0A1L3MU58
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS03655
gene id: 1547283:A9C19_RS03655
uniprot id: A0A1L3MNI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1547283:A9C19 RS20935
gene id: 1547283:A9C19_RS20935
uniprot id: A0A1L3MX19
names: Similarity
messages: Belongs to the EsaB family.

1547283:A9C19 RS00690
gene id: 1547283:A9C19_RS00690
uniprot id: A0A1L3MMA2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1547283:A9C19 RS11460
gene id: 1547283:A9C19_RS11460
uniprot id: A0A1L3MSH0
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1547283:A9C19 RS17065
gene id: 1547283:A9C19_RS17065
uniprot id: A0A1L3MV81
names: Similarity
messages: Belongs to the UPF0374 family.

1547283:A9C19 RS17640
gene id: 1547283:A9C19_RS17640
uniprot id: A0A1L3MXU0
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1547283:A9C19 RS11170
gene id: 1547283:A9C19_RS11170
uniprot id: A0A1L3MSF8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS19490
gene id: 1547283:A9C19_RS19490
uniprot id: A0A1L3MWC2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1547283:A9C19 RS17700
gene id: 1547283:A9C19_RS17700
uniprot id: A0A1L3MVI3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS05565
gene id: 1547283:A9C19_RS05565
uniprot id: A0A1L3MPF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1547283:A9C19 RS06205
gene id: 1547283:A9C19_RS06205
uniprot id: A0A1L3MPR8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1547283:A9C19 RS15565
gene id: 1547283:A9C19_RS15565
uniprot id: A0A1L3MUN3
names: Similarity
messages: Belongs to the malate synthase family.

1547283:A9C19 RS19080
gene id: 1547283:A9C19_RS19080
uniprot id: A0A1L3MW74
names: Similarity
messages: Belongs to the LOG family.

1547283:A9C19 RS15540
gene id: 1547283:A9C19_RS15540
uniprot id: A0A1L3MUG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS00430
gene id: 1547283:A9C19_RS00430
uniprot id: A0A1L3MLX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1547283:A9C19 RS12670
gene id: 1547283:A9C19_RS12670
uniprot id: A0A1L3MT23
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS17535
gene id: 1547283:A9C19_RS17535
uniprot id: A0A1L3MVH4
names: Similarity
messages: Belongs to the UPF0178 family.

1547283:A9C19 RS03735
gene id: 1547283:A9C19_RS03735
uniprot id: A0A1L3MNP5
names: Similarity
messages: Belongs to the FBPase class 2 family.

1547283:A9C19 RS09855
gene id: 1547283:A9C19_RS09855
uniprot id: A0A1L3MRN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS06300
gene id: 1547283:A9C19_RS06300
uniprot id: A0A1L3MQ28
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1547283:A9C19 RS20460
gene id: 1547283:A9C19_RS20460
uniprot id: A0A1L3MY18
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1547283:A9C19 RS05950
gene id: 1547283:A9C19_RS05950
uniprot id: A0A1L3MPL9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1547283:A9C19 RS19530
gene id: 1547283:A9C19_RS19530
uniprot id: A0A1L3MWC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1547283:A9C19 RS01060
gene id: 1547283:A9C19_RS01060
uniprot id: A0A1L3MMA3
names: Similarity
messages: Belongs to the CpsD/CapB family.

1547283:A9C19 RS20790
gene id: 1547283:A9C19_RS20790
uniprot id: A0A1L3MWY4
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1547283:A9C19 RS18485
gene id: 1547283:A9C19_RS18485
uniprot id: A0A1L3MW43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fosfomycin resistance protein family. FosB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.

1547283:A9C19 RS11485
gene id: 1547283:A9C19_RS11485
uniprot id: A0A1L3MSH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1547283:A9C19 RS04500
gene id: 1547283:A9C19_RS04500
uniprot id: A0A1L3MP01
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1547283:A9C19 RS18605
gene id: 1547283:A9C19_RS18605
uniprot id: A0A1L3MW02
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1547283:A9C19 RS04875
gene id: 1547283:A9C19_RS04875
uniprot id: A0A1L3MPF2
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1547283:A9C19 RS07055
gene id: 1547283:A9C19_RS07055
uniprot id: A0A1L3MQ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1547283:A9C19 RS03235
gene id: 1547283:A9C19_RS03235
uniprot id: A0A1L3MNK8
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS12290
gene id: 1547283:A9C19_RS12290
uniprot id: A0A1L3MSV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1547283:A9C19 RS11130
gene id: 1547283:A9C19_RS11130
uniprot id: A0A1L3MS85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1547283:A9C19 RS19260
gene id: 1547283:A9C19_RS19260
uniprot id: A0A1L3MWE9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1547283:A9C19 RS10295
gene id: 1547283:A9C19_RS10295
uniprot id: A0A1L3MRX0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1547283:A9C19 RS04695
gene id: 1547283:A9C19_RS04695
uniprot id: A0A1L3MP18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

1547283:A9C19 RS11810
gene id: 1547283:A9C19_RS11810
uniprot id: A0A1L3MSR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1547283:A9C19 RS19925
gene id: 1547283:A9C19_RS19925
uniprot id: A0A1L3MWK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1547283:A9C19 RS10485
gene id: 1547283:A9C19_RS10485
uniprot id: A0A1L3MRZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

1547283:A9C19 RS00680
gene id: 1547283:A9C19_RS00680
uniprot id: A0A1L3MM47
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1547283:A9C19 RS14095
gene id: 1547283:A9C19_RS14095
uniprot id: A0A1L3MTP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1547283:A9C19 RS17805
gene id: 1547283:A9C19_RS17805
uniprot id: A0A1L3MVL3
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS18100
gene id: 1547283:A9C19_RS18100
uniprot id: A0A1L3MVR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

1547283:A9C19 RS02805
gene id: 1547283:A9C19_RS02805
uniprot id: A0A1L3MN35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS15335
gene id: 1547283:A9C19_RS15335
uniprot id: A0A1L3MUE5
names: Similarity
messages: Belongs to the CvfB family.

1547283:A9C19 RS06830
gene id: 1547283:A9C19_RS06830
uniprot id: A0A1L3MQ40
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1547283:A9C19 RS07610
gene id: 1547283:A9C19_RS07610
uniprot id: A0A1L3MQS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.
messages: Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan.

1547283:A9C19 RS14630
gene id: 1547283:A9C19_RS14630
uniprot id: A0A1L3MU29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1547283:A9C19 RS05415
gene id: 1547283:A9C19_RS05415
uniprot id: A0A1L3MXF4
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS00580
gene id: 1547283:A9C19_RS00580
uniprot id: A0A1L3MM89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS00275
gene id: 1547283:A9C19_RS00275
uniprot id: A0A1L3MLU7
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1547283:A9C19 RS04555
gene id: 1547283:A9C19_RS04555
uniprot id: A0A1L3MNW4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1547283:A9C19 RS06930
gene id: 1547283:A9C19_RS06930
uniprot id: A0A1L3MQ59
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1547283:A9C19 RS00100
gene id: 1547283:A9C19_RS00100
uniprot id: A0A1L3MLR7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1547283:A9C19 RS02335
gene id: 1547283:A9C19_RS02335
uniprot id: A0A1L3MMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1547283:A9C19 RS16625
gene id: 1547283:A9C19_RS16625
uniprot id: A0A1L3MV22
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1547283:A9C19 RS03775
gene id: 1547283:A9C19_RS03775
uniprot id: A0A1L3MNM2
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1547283:A9C19 RS18060
gene id: 1547283:A9C19_RS18060
uniprot id: A0A1L3MVS3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1547283:A9C19 RS11380
gene id: 1547283:A9C19_RS11380
uniprot id: A0A1L3MSK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1547283:A9C19 RS12885
gene id: 1547283:A9C19_RS12885
uniprot id: A0A1L3MTA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.
messages: Membrane

1547283:A9C19 RS17800
gene id: 1547283:A9C19_RS17800
uniprot id: A0A1L3MVK2
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS20235
gene id: 1547283:A9C19_RS20235
uniprot id: A0A1L3MWU5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS05420
gene id: 1547283:A9C19_RS05420
uniprot id: A0A1L3MPB5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1547283:A9C19 RS00665
gene id: 1547283:A9C19_RS00665
uniprot id: A0A1L3MM11
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1547283:A9C19 RS05625
gene id: 1547283:A9C19_RS05625
uniprot id: A0A1L3MPF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1547283:A9C19 RS14330
gene id: 1547283:A9C19_RS14330
uniprot id: A0A1L3MTU0
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS02880
gene id: 1547283:A9C19_RS02880
uniprot id: A0A1L3MN77
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1547283:A9C19 RS01140
gene id: 1547283:A9C19_RS01140
uniprot id: A0A1L3MMI4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1547283:A9C19 RS03185
gene id: 1547283:A9C19_RS03185
uniprot id: A0A1L3MNH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS02535
gene id: 1547283:A9C19_RS02535
uniprot id: A0A1L3MMY4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1547283:A9C19 RS12935
gene id: 1547283:A9C19_RS12935
uniprot id: A0A1L3MXM9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

1547283:A9C19 RS10345
gene id: 1547283:A9C19_RS10345
uniprot id: A0A1L3MRW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1547283:A9C19 RS04275
gene id: 1547283:A9C19_RS04275
uniprot id: A0A1L3MNR2
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS08550
gene id: 1547283:A9C19_RS08550
uniprot id: A0A1L3MQW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Spore core

1547283:A9C19 RS12400
gene id: 1547283:A9C19_RS12400
uniprot id: A0A1L3MSZ4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1547283:A9C19 RS05910
gene id: 1547283:A9C19_RS05910
uniprot id: A0A1L3MPN7
names: Similarity
messages: Belongs to the UPF0297 family.

1547283:A9C19 RS01690
gene id: 1547283:A9C19_RS01690
uniprot id: A0A1L3MMJ6
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS11795
gene id: 1547283:A9C19_RS11795
uniprot id: A0A1L3MSL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.
messages: Self-associates. Interacts with SigE. Interacts with SpoIIR.

1547283:A9C19 RS06485
gene id: 1547283:A9C19_RS06485
uniprot id: A0A1L3MPY0
names: Similarity
messages: Belongs to the ArsC family.

1547283:A9C19 RS03525
gene id: 1547283:A9C19_RS03525
uniprot id: A0A1L3MNI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS06265
gene id: 1547283:A9C19_RS06265
uniprot id: A0A1L3MPT9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1547283:A9C19 RS19195
gene id: 1547283:A9C19_RS19195
uniprot id: A0A1L3MW80
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1547283:A9C19 RS16190
gene id: 1547283:A9C19_RS16190
uniprot id: A0A1L3MUV1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1547283:A9C19 RS15595
gene id: 1547283:A9C19_RS15595
uniprot id: A0A1L3MUI0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS06825
gene id: 1547283:A9C19_RS06825
uniprot id: A0A1L3MQ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1547283:A9C19 RS16815
gene id: 1547283:A9C19_RS16815
uniprot id: A0A1L3MV63
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1547283:A9C19 RS14665
gene id: 1547283:A9C19_RS14665
uniprot id: A0A1L3MXR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS08420
gene id: 1547283:A9C19_RS08420
uniprot id: A0A1L3MQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1547283:A9C19 RS01030
gene id: 1547283:A9C19_RS01030
uniprot id: A0A1L3MM87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS02060
gene id: 1547283:A9C19_RS02060
uniprot id: A0A1L3MMR6
names: Similarity
messages: Belongs to the UPF0111 family.

1547283:A9C19 RS07040
gene id: 1547283:A9C19_RS07040
uniprot id: A0A1L3MQ73
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1547283:A9C19 RS15180
gene id: 1547283:A9C19_RS15180
uniprot id: A0A1L3MUB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS10185
gene id: 1547283:A9C19_RS10185
uniprot id: A0A1L3MRS2
names: Similarity
messages: Belongs to the universal stress protein A family.

1547283:A9C19 RS06630
gene id: 1547283:A9C19_RS06630
uniprot id: A0A1L3MQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1547283:A9C19 RS06895
gene id: 1547283:A9C19_RS06895
uniprot id: A0A1L3MXE3
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1547283:A9C19 RS05600
gene id: 1547283:A9C19_RS05600
uniprot id: A0A1L3MPF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1547283:A9C19 RS19720
gene id: 1547283:A9C19_RS19720
uniprot id: A0A1L3MWH0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1547283:A9C19 RS01810
gene id: 1547283:A9C19_RS01810
uniprot id: A0A1L3MMK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1547283:A9C19 RS05410
gene id: 1547283:A9C19_RS05410
uniprot id: A0A1L3MPC1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1547283:A9C19 RS12245
gene id: 1547283:A9C19_RS12245
uniprot id: A0A1L3MSV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1547283:A9C19 RS20535
gene id: 1547283:A9C19_RS20535
uniprot id: A0A1L3MWT3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1547283:A9C19 RS15765
gene id: 1547283:A9C19_RS15765
uniprot id: A0A1L3MUM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS10425
gene id: 1547283:A9C19_RS10425
uniprot id: A0A1L3MS60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1547283:A9C19 RS02755
gene id: 1547283:A9C19_RS02755
uniprot id: A0A1L3MN17
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS00890
gene id: 1547283:A9C19_RS00890
uniprot id: A0A1L3MM41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1547283:A9C19 RS10410
gene id: 1547283:A9C19_RS10410
uniprot id: A0A1L3MRW0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1547283:A9C19 RS17440
gene id: 1547283:A9C19_RS17440
uniprot id: A0A1L3MVL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1547283:A9C19 RS19770
gene id: 1547283:A9C19_RS19770
uniprot id: A0A1L3MWI7
names: Similarity
messages: Belongs to the CtsR family.

1547283:A9C19 RS11465
gene id: 1547283:A9C19_RS11465
uniprot id: A0A1L3MSH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1547283:A9C19 RS03400
gene id: 1547283:A9C19_RS03400
uniprot id: A0A1L3MNE3
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

1547283:A9C19 RS04115
gene id: 1547283:A9C19_RS04115
uniprot id: A0A1L3MNN8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS04490
gene id: 1547283:A9C19_RS04490
uniprot id: A0A1L3MNY0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS18820
gene id: 1547283:A9C19_RS18820
uniprot id: A0A1L3MW89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1547283:A9C19 RS02065
gene id: 1547283:A9C19_RS02065
uniprot id: A0A1L3MMP4
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS14515
gene id: 1547283:A9C19_RS14515
uniprot id: A0A1L3MXR1
names: Similarity
messages: Belongs to the FGGY kinase family.

1547283:A9C19 RS10500
gene id: 1547283:A9C19_RS10500
uniprot id: A0A1L3MRZ8
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspP family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

1547283:A9C19 RS09845
gene id: 1547283:A9C19_RS09845
uniprot id: A0A1L3MRM1
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS03080
gene id: 1547283:A9C19_RS03080
uniprot id: A0A1L3MNA7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1547283:A9C19 RS00880
gene id: 1547283:A9C19_RS00880
uniprot id: A0A1L3MM43
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1547283:A9C19 RS15240
gene id: 1547283:A9C19_RS15240
uniprot id: A0A1L3MXR0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS19915
gene id: 1547283:A9C19_RS19915
uniprot id: A0A1L3MXX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS11385
gene id: 1547283:A9C19_RS11385
uniprot id: A0A1L3MSE8
names: Similarity
messages: Belongs to the DprA/Smf family.

1547283:A9C19 RS12300
gene id: 1547283:A9C19_RS12300
uniprot id: A0A1L3MSX4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1547283:A9C19 RS19475
gene id: 1547283:A9C19_RS19475
uniprot id: A0A1L3MWD2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1547283:A9C19 RS10775
gene id: 1547283:A9C19_RS10775
uniprot id: A0A1L3MS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1547283:A9C19 RS16265
gene id: 1547283:A9C19_RS16265
uniprot id: A0A1L3MUT4
names: Similarity
messages: Belongs to the catalase family.

1547283:A9C19 RS04155
gene id: 1547283:A9C19_RS04155
uniprot id: A0A1L3MP40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1547283:A9C19 RS06065
gene id: 1547283:A9C19_RS06065
uniprot id: A0A1L3MPP2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1547283:A9C19 RS20910
gene id: 1547283:A9C19_RS20910
uniprot id: A0A1L3MX07
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS06135
gene id: 1547283:A9C19_RS06135
uniprot id: A0A1L3MPU2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1547283:A9C19 RS00720
gene id: 1547283:A9C19_RS00720
uniprot id: A0A1L3MM21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS02930
gene id: 1547283:A9C19_RS02930
uniprot id: A0A1L3MN51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1547283:A9C19 RS07105
gene id: 1547283:A9C19_RS07105
uniprot id: A0A1L3MQ86
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

1547283:A9C19 RS14180
gene id: 1547283:A9C19_RS14180
uniprot id: A0A1L3MTT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Secreted

1547283:A9C19 RS11935
gene id: 1547283:A9C19_RS11935
uniprot id: A0A1L3MSQ0
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS19485
gene id: 1547283:A9C19_RS19485
uniprot id: A0A1L3MWH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1547283:A9C19 RS19930
gene id: 1547283:A9C19_RS19930
uniprot id: A0A1L3MWJ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1547283:A9C19 RS19000
gene id: 1547283:A9C19_RS19000
uniprot id: A0A1L3MW64
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1547283:A9C19 RS20070
gene id: 1547283:A9C19_RS20070
uniprot id: A0A1L3MWM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1547283:A9C19 RS12890
gene id: 1547283:A9C19_RS12890
uniprot id: A0A1L3MT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07015
gene id: 1547283:A9C19_RS07015
uniprot id: A0A1L3MQ69
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS08670
gene id: 1547283:A9C19_RS08670
uniprot id: A0A1L3MR50
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1547283:A9C19 RS20440
gene id: 1547283:A9C19_RS20440
uniprot id: A0A1L3MWS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1547283:A9C19 RS04430
gene id: 1547283:A9C19_RS04430
uniprot id: A0A1L3MNW3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS06430
gene id: 1547283:A9C19_RS06430
uniprot id: A0A1L3MPW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS05435
gene id: 1547283:A9C19_RS05435
uniprot id: A0A1L3MPP9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS04095
gene id: 1547283:A9C19_RS04095
uniprot id: A0A1L3MX73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1547283:A9C19 RS19500
gene id: 1547283:A9C19_RS19500
uniprot id: A0A1L3MWD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1547283:A9C19 RS15095
gene id: 1547283:A9C19_RS15095
uniprot id: A0A1L3MU94
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1547283:A9C19 RS11895
gene id: 1547283:A9C19_RS11895
uniprot id: A0A1L3MSQ8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1547283:A9C19 RS03880
gene id: 1547283:A9C19_RS03880
uniprot id: A0A1L3MNM6
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS10220
gene id: 1547283:A9C19_RS10220
uniprot id: A0A1L3MRU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1547283:A9C19 RS06805
gene id: 1547283:A9C19_RS06805
uniprot id: A0A1L3MQC9
names: Similarity
messages: Belongs to the asp23 family.

1547283:A9C19 RS12800
gene id: 1547283:A9C19_RS12800
uniprot id: A0A1L3MT47
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS05825
gene id: 1547283:A9C19_RS05825
uniprot id: A0A1L3MPK1
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1547283:A9C19 RS13665
gene id: 1547283:A9C19_RS13665
uniprot id: A0A1L3MTJ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS02255
gene id: 1547283:A9C19_RS02255
uniprot id: A0A1L3MMT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1547283:A9C19 RS04950
gene id: 1547283:A9C19_RS04950
uniprot id: A0A1L3MP38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1547283:A9C19 RS07190
gene id: 1547283:A9C19_RS07190
uniprot id: A0A1L3MQ99
names: Subcellular Location Annotation
messages: Cell membrane

1547283:A9C19 RS11860
gene id: 1547283:A9C19_RS11860
uniprot id: A0A1L3MSM8
names: Similarity
messages: Belongs to the transpeptidase family.

1547283:A9C19 RS18355
gene id: 1547283:A9C19_RS18355
uniprot id: A0A1L3MVV8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1547283:A9C19 RS05700
gene id: 1547283:A9C19_RS05700
uniprot id: A0A1L3MPI2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1547283:A9C19 RS07390
gene id: 1547283:A9C19_RS07390
uniprot id: A0A1L3MQM6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1547283:A9C19 RS18565
gene id: 1547283:A9C19_RS18565
uniprot id: A0A1L3MVX8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1547283:A9C19 RS16300
gene id: 1547283:A9C19_RS16300
uniprot id: A0A1L3MUW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.
messages: Membrane

1547283:A9C19 RS02760
gene id: 1547283:A9C19_RS02760
uniprot id: A0A1L3MN57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS17925
gene id: 1547283:A9C19_RS17925
uniprot id: A0A1L3MVM9
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS20040
gene id: 1547283:A9C19_RS20040
uniprot id: A0A1L3MWK9
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1547283:A9C19 RS06900
gene id: 1547283:A9C19_RS06900
uniprot id: A0A1L3MQ46
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1547283:A9C19 RS14655
gene id: 1547283:A9C19_RS14655
uniprot id: A0A1L3MU27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS00485
gene id: 1547283:A9C19_RS00485
uniprot id: A0A1L3MX37
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1547283:A9C19 RS17290
gene id: 1547283:A9C19_RS17290
uniprot id: A0A1L3MVB4
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS15010
gene id: 1547283:A9C19_RS15010
uniprot id: A0A1L3MU89
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1547283:A9C19 RS15100
gene id: 1547283:A9C19_RS15100
uniprot id: A0A1L3MU85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
messages: Belongs to the SpxH family.
messages: Cytoplasm
messages: Interacts with Spx.

1547283:A9C19 RS17425
gene id: 1547283:A9C19_RS17425
uniprot id: A0A1L3MVD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family. IolA subfamily.
messages: Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
messages: Homotetramer.

1547283:A9C19 RS09455
gene id: 1547283:A9C19_RS09455
uniprot id: A0A1L3MRN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS06005
gene id: 1547283:A9C19_RS06005
uniprot id: A0A1L3MPM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1547283:A9C19 RS09280
gene id: 1547283:A9C19_RS09280
uniprot id: A0A1L3MRF0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1547283:A9C19 RS17345
gene id: 1547283:A9C19_RS17345
uniprot id: A0A1L3MVB5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1547283:A9C19 RS05650
gene id: 1547283:A9C19_RS05650
uniprot id: A0A1L3MPK8
names: Similarity
messages: Belongs to the UPF0735 family.

1547283:A9C19 RS19685
gene id: 1547283:A9C19_RS19685
uniprot id: A0A1L3MWL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1547283:A9C19 RS03645
gene id: 1547283:A9C19_RS03645
uniprot id: A0A1L3MNH7
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS03580
gene id: 1547283:A9C19_RS03580
uniprot id: A0A1L3MNH4
names: Similarity
messages: Belongs to the UPF0047 family.

1547283:A9C19 RS04600
gene id: 1547283:A9C19_RS04600
uniprot id: A0A1L3MP23
names: Similarity
messages: Belongs to the peptidase M29 family.

1547283:A9C19 RS19880
gene id: 1547283:A9C19_RS19880
uniprot id: A0A1L3MWI1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1547283:A9C19 RS12265
gene id: 1547283:A9C19_RS12265
uniprot id: A0A1L3MXM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1547283:A9C19 RS08535
gene id: 1547283:A9C19_RS08535
uniprot id: A0A1L3MQZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1547283:A9C19 RS04580
gene id: 1547283:A9C19_RS04580
uniprot id: A0A1L3MNW6
names: Similarity
messages: Belongs to the UPF0354 family.

1547283:A9C19 RS04755
gene id: 1547283:A9C19_RS04755
uniprot id: A0A1L3MNZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1547283:A9C19 RS15885
gene id: 1547283:A9C19_RS15885
uniprot id: A0A1L3MUM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SscA family.
messages: Membrane

1547283:A9C19 RS06305
gene id: 1547283:A9C19_RS06305
uniprot id: A0A1L3MPV1
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1547283:A9C19 RS00480
gene id: 1547283:A9C19_RS00480
uniprot id: A0A1L3MLW6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1547283:A9C19 RS02020
gene id: 1547283:A9C19_RS02020
uniprot id: A0A1L3MX55
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

1547283:A9C19 RS13985
gene id: 1547283:A9C19_RS13985
uniprot id: A0A1L3MTN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS00540
gene id: 1547283:A9C19_RS00540
uniprot id: A0A1L3MLZ8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1547283:A9C19 RS14155
gene id: 1547283:A9C19_RS14155
uniprot id: A0A1L3MTT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1547283:A9C19 RS03065
gene id: 1547283:A9C19_RS03065
uniprot id: A0A1L3MNF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

1547283:A9C19 RS12380
gene id: 1547283:A9C19_RS12380
uniprot id: A0A1L3MSY2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1547283:A9C19 RS00390
gene id: 1547283:A9C19_RS00390
uniprot id: A0A1L3MLV2
names: Similarity
messages: Belongs to the UPF0741 family.

1547283:A9C19 RS12425
gene id: 1547283:A9C19_RS12425
uniprot id: A0A1L3MSX5
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS14395
gene id: 1547283:A9C19_RS14395
uniprot id: A0A1L3MU16
names: Similarity
messages: Belongs to the aldose epimerase family.

1547283:A9C19 RS10010
gene id: 1547283:A9C19_RS10010
uniprot id: A0A1L3MRQ2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1547283:A9C19 RS12920
gene id: 1547283:A9C19_RS12920
uniprot id: A0A1L3MT66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1547283:A9C19 RS03285
gene id: 1547283:A9C19_RS03285
uniprot id: A0A1L3MNC2
names: Similarity
messages: Belongs to the CdaR family.

1547283:A9C19 RS01740
gene id: 1547283:A9C19_RS01740
uniprot id: A0A1L3MMK9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.

1547283:A9C19 RS03660
gene id: 1547283:A9C19_RS03660
uniprot id: A0A1L3MNH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1547283:A9C19 RS06615
gene id: 1547283:A9C19_RS06615
uniprot id: A0A1L3MPZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1547283:A9C19 RS12310
gene id: 1547283:A9C19_RS12310
uniprot id: A0A1L3MSW8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1547283:A9C19 RS16015
gene id: 1547283:A9C19_RS16015
uniprot id: A0A1L3MUR2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1547283:A9C19 RS08660
gene id: 1547283:A9C19_RS08660
uniprot id: A0A1L3MQY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1547283:A9C19 RS15050
gene id: 1547283:A9C19_RS15050
uniprot id: A0A1L3MUE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1547283:A9C19 RS07805
gene id: 1547283:A9C19_RS07805
uniprot id: A0A1L3MQN0
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

1547283:A9C19 RS19520
gene id: 1547283:A9C19_RS19520
uniprot id: A0A1L3MWD7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1547283:A9C19 RS06360
gene id: 1547283:A9C19_RS06360
uniprot id: A0A1L3MPV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1547283:A9C19 RS10990
gene id: 1547283:A9C19_RS10990
uniprot id: A0A1L3MSC2
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS06905
gene id: 1547283:A9C19_RS06905
uniprot id: A0A1L3MQ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1547283:A9C19 RS16490
gene id: 1547283:A9C19_RS16490
uniprot id: A0A1L3MUY9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1547283:A9C19 RS00730
gene id: 1547283:A9C19_RS00730
uniprot id: A0A1L3MM49
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1547283:A9C19 RS13305
gene id: 1547283:A9C19_RS13305
uniprot id: A0A1L3MTE5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1547283:A9C19 RS04415
gene id: 1547283:A9C19_RS04415
uniprot id: A0A1L3MNT4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1547283:A9C19 RS00375
gene id: 1547283:A9C19_RS00375
uniprot id: A0A1L3MX81
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

1547283:A9C19 RS12455
gene id: 1547283:A9C19_RS12455
uniprot id: A0A1L3MT04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07700
gene id: 1547283:A9C19_RS07700
uniprot id: A0A1L3MQN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1547283:A9C19 RS09520
gene id: 1547283:A9C19_RS09520
uniprot id: A0A1L3MRD9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1547283:A9C19 RS10985
gene id: 1547283:A9C19_RS10985
uniprot id: A0A1L3MS82
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS19140
gene id: 1547283:A9C19_RS19140
uniprot id: A0A1L3MW82
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS02420
gene id: 1547283:A9C19_RS02420
uniprot id: A0A1L3MMW8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1547283:A9C19 RS05475
gene id: 1547283:A9C19_RS05475
uniprot id: A0A1L3MPD0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1547283:A9C19 RS13105
gene id: 1547283:A9C19_RS13105
uniprot id: A0A1L3MTF2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS11200
gene id: 1547283:A9C19_RS11200
uniprot id: A0A1L3MSC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CheD family.
messages: Deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the cheA kinase.
messages: Forms a complex with CheC.

1547283:A9C19 RS00535
gene id: 1547283:A9C19_RS00535
uniprot id: A0A1L3MLY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1547283:A9C19 RS14625
gene id: 1547283:A9C19_RS14625
uniprot id: A0A1L3MU10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
messages: Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
messages: Cytoplasm

1547283:A9C19 RS02885
gene id: 1547283:A9C19_RS02885
uniprot id: A0A1L3MX84
names: Similarity
messages: Belongs to the ArsC family.

1547283:A9C19 RS07785
gene id: 1547283:A9C19_RS07785
uniprot id: A0A1L3MQK3
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS03590
gene id: 1547283:A9C19_RS03590
uniprot id: A0A1L3MNH2
names: Function
names: Similarity
messages: Belongs to the bacillus TGase family.
messages: Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links.

1547283:A9C19 RS05915
gene id: 1547283:A9C19_RS05915
uniprot id: A0A1L3MPM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1547283:A9C19 RS14230
gene id: 1547283:A9C19_RS14230
uniprot id: A0A1L3MTT5
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS03675
gene id: 1547283:A9C19_RS03675
uniprot id: A0A1L3MNJ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

1547283:A9C19 RS08070
gene id: 1547283:A9C19_RS08070
uniprot id: A0A1L3MQQ3
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS10315
gene id: 1547283:A9C19_RS10315
uniprot id: A0A1L3MS39
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS12435
gene id: 1547283:A9C19_RS12435
uniprot id: A0A1L3MT28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1547283:A9C19 RS10860
gene id: 1547283:A9C19_RS10860
uniprot id: A0A1L3MS57
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1547283:A9C19 RS10440
gene id: 1547283:A9C19_RS10440
uniprot id: A0A1L3MRZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1547283:A9C19 RS00760
gene id: 1547283:A9C19_RS00760
uniprot id: A0A1L3MM34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1547283:A9C19 RS02170
gene id: 1547283:A9C19_RS02170
uniprot id: A0A1L3MMT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1547283:A9C19 RS19480
gene id: 1547283:A9C19_RS19480
uniprot id: A0A1L3MWC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1547283:A9C19 RS00490
gene id: 1547283:A9C19_RS00490
uniprot id: A0A1L3MLY9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1547283:A9C19 RS06410
gene id: 1547283:A9C19_RS06410
uniprot id: A0A1L3MPW0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1547283:A9C19 RS02245
gene id: 1547283:A9C19_RS02245
uniprot id: A0A1L3MMW7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1547283:A9C19 RS07580
gene id: 1547283:A9C19_RS07580
uniprot id: A0A1L3MQG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1547283:A9C19 RS15160
gene id: 1547283:A9C19_RS15160
uniprot id: A0A1L3MUB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS13015
gene id: 1547283:A9C19_RS13015
uniprot id: A0A1L3MT82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
messages: Homotetramer.

1547283:A9C19 RS01470
gene id: 1547283:A9C19_RS01470
uniprot id: A0A1L3MMD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

1547283:A9C19 RS13540
gene id: 1547283:A9C19_RS13540
uniprot id: A0A1L3MTG6
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS19525
gene id: 1547283:A9C19_RS19525
uniprot id: A0A1L3MWE2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1547283:A9C19 RS17460
gene id: 1547283:A9C19_RS17460
uniprot id: A0A1L3MVF5
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS07595
gene id: 1547283:A9C19_RS07595
uniprot id: A0A1L3MQI1
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

1547283:A9C19 RS08100
gene id: 1547283:A9C19_RS08100
uniprot id: A0A1L3MR13
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1547283:A9C19 RS08320
gene id: 1547283:A9C19_RS08320
uniprot id: A0A1L3MQZ3
names: Subunit
messages: Homodimer.

1547283:A9C19 RS07265
gene id: 1547283:A9C19_RS07265
uniprot id: A0A1L3MQF1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1547283:A9C19 RS11140
gene id: 1547283:A9C19_RS11140
uniprot id: A0A1L3MSF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS04900
gene id: 1547283:A9C19_RS04900
uniprot id: A0A1L3MP27
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1547283:A9C19 RS15140
gene id: 1547283:A9C19_RS15140
uniprot id: A0A1L3MU91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

1547283:A9C19 RS04725
gene id: 1547283:A9C19_RS04725
uniprot id: A0A1L3MP11
names: Similarity
messages: Belongs to the peptidase S49 family.

1547283:A9C19 RS20855
gene id: 1547283:A9C19_RS20855
uniprot id: A0A1L3MX17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1547283:A9C19 RS02165
gene id: 1547283:A9C19_RS02165
uniprot id: A0A1L3MMU2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1547283:A9C19 RS14225
gene id: 1547283:A9C19_RS14225
uniprot id: A0A1L3MTY3
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1547283:A9C19 RS08925
gene id: 1547283:A9C19_RS08925
uniprot id: A0A1L3MR59
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1547283:A9C19 RS18030
gene id: 1547283:A9C19_RS18030
uniprot id: A0A1L3MVP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS05680
gene id: 1547283:A9C19_RS05680
uniprot id: A0A1L3MPG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1547283:A9C19 RS01555
gene id: 1547283:A9C19_RS01555
uniprot id: A0A1L3MMJ1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1547283:A9C19 RS11290
gene id: 1547283:A9C19_RS11290
uniprot id: A0A1L3MSE4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1547283:A9C19 RS11005
gene id: 1547283:A9C19_RS11005
uniprot id: A0A1L3MS92
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1547283:A9C19 RS11015
gene id: 1547283:A9C19_RS11015
uniprot id: A0A1L3MS91
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1547283:A9C19 RS18830
gene id: 1547283:A9C19_RS18830
uniprot id: A0A1L3MW50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1547283:A9C19 RS17660
gene id: 1547283:A9C19_RS17660
uniprot id: A0A1L3MVH9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1547283:A9C19 RS00435
gene id: 1547283:A9C19_RS00435
uniprot id: A0A1L3MLX2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1547283:A9C19 RS18445
gene id: 1547283:A9C19_RS18445
uniprot id: A0A1L3MVY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1547283:A9C19 RS08920
gene id: 1547283:A9C19_RS08920
uniprot id: A0A1L3MR75
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1547283:A9C19 RS13055
gene id: 1547283:A9C19_RS13055
uniprot id: A0A1L3MTA2
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1547283:A9C19 RS14300
gene id: 1547283:A9C19_RS14300
uniprot id: A0A1L3MTX8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1547283:A9C19 RS00285
gene id: 1547283:A9C19_RS00285
uniprot id: A0A1L3MLY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS05605
gene id: 1547283:A9C19_RS05605
uniprot id: A0A1L3MPR5
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1547283:A9C19 RS05985
gene id: 1547283:A9C19_RS05985
uniprot id: A0A1L3MPN1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1547283:A9C19 RS19515
gene id: 1547283:A9C19_RS19515
uniprot id: A0A1L3MWC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1547283:A9C19 RS05380
gene id: 1547283:A9C19_RS05380
uniprot id: A0A1L3MPN3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1547283:A9C19 RS01705
gene id: 1547283:A9C19_RS01705
uniprot id: A0A1L3MMH4
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS00575
gene id: 1547283:A9C19_RS00575
uniprot id: A0A1L3MLY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS17005
gene id: 1547283:A9C19_RS17005
uniprot id: A0A1L3MV58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1547283:A9C19 RS04660
gene id: 1547283:A9C19_RS04660
uniprot id: A0A1L3MPA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS20800
gene id: 1547283:A9C19_RS20800
uniprot id: A0A1L3MWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS09550
gene id: 1547283:A9C19_RS09550
uniprot id: A0A1L3MRH5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07935
gene id: 1547283:A9C19_RS07935
uniprot id: A0A1L3MQY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

1547283:A9C19 RS07645
gene id: 1547283:A9C19_RS07645
uniprot id: A0A1L3MQJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS05150
gene id: 1547283:A9C19_RS05150
uniprot id: A0A1L3MP76
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1547283:A9C19 RS18970
gene id: 1547283:A9C19_RS18970
uniprot id: A0A1L3MW58
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

1547283:A9C19 RS05920
gene id: 1547283:A9C19_RS05920
uniprot id: A0A1L3MPL4
names: Similarity
messages: Belongs to the UPF0473 family.

1547283:A9C19 RS06465
gene id: 1547283:A9C19_RS06465
uniprot id: A0A1L3MQ62
names: Similarity
messages: Belongs to the UPF0045 family.

1547283:A9C19 RS06510
gene id: 1547283:A9C19_RS06510
uniprot id: A0A1L3MPX3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

1547283:A9C19 RS00350
gene id: 1547283:A9C19_RS00350
uniprot id: A0A1L3MLZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1547283:A9C19 RS11195
gene id: 1547283:A9C19_RS11195
uniprot id: A0A1L3MXJ7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1547283:A9C19 RS10950
gene id: 1547283:A9C19_RS10950
uniprot id: A0A1L3MS72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1547283:A9C19 RS07510
gene id: 1547283:A9C19_RS07510
uniprot id: A0A1L3MQE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors.
messages: Membrane

1547283:A9C19 RS06365
gene id: 1547283:A9C19_RS06365
uniprot id: A0A1L3MQ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1547283:A9C19 RS02960
gene id: 1547283:A9C19_RS02960
uniprot id: A0A1L3MN67
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1547283:A9C19 RS19600
gene id: 1547283:A9C19_RS19600
uniprot id: A0A1L3MWF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1547283:A9C19 RS08905
gene id: 1547283:A9C19_RS08905
uniprot id: A0A1L3MR55
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS20300
gene id: 1547283:A9C19_RS20300
uniprot id: A0A1L3MWR2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1547283:A9C19 RS20430
gene id: 1547283:A9C19_RS20430
uniprot id: A0A1L3MXW9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1547283:A9C19 RS02185
gene id: 1547283:A9C19_RS02185
uniprot id: A0A1L3MMS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1547283:A9C19 RS04630
gene id: 1547283:A9C19_RS04630
uniprot id: A0A1L3MNX6
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1547283:A9C19 RS19065
gene id: 1547283:A9C19_RS19065
uniprot id: A0A1L3MWB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1547283:A9C19 RS08965
gene id: 1547283:A9C19_RS08965
uniprot id: A0A1L3MR34
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1547283:A9C19 RS19010
gene id: 1547283:A9C19_RS19010
uniprot id: A0A1L3MW49
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1547283:A9C19 RS06800
gene id: 1547283:A9C19_RS06800
uniprot id: A0A1L3MQ43
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1547283:A9C19 RS05440
gene id: 1547283:A9C19_RS05440
uniprot id: A0A1L3MPC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS10525
gene id: 1547283:A9C19_RS10525
uniprot id: A0A1L3MS79
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1547283:A9C19 RS00520
gene id: 1547283:A9C19_RS00520
uniprot id: A0A1L3MM13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS02620
gene id: 1547283:A9C19_RS02620
uniprot id: A0A1L3MN47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1547283:A9C19 RS00105
gene id: 1547283:A9C19_RS00105
uniprot id: A0A1L3MLR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1547283:A9C19 RS17850
gene id: 1547283:A9C19_RS17850
uniprot id: A0A1L3MVL2
names: Similarity
messages: Belongs to the peptidase S1 family.

1547283:A9C19 RS14660
gene id: 1547283:A9C19_RS14660
uniprot id: A0A1L3MU59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS02030
gene id: 1547283:A9C19_RS02030
uniprot id: A0A1L3MMS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS19560
gene id: 1547283:A9C19_RS19560
uniprot id: A0A1L3MWE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1547283:A9C19 RS02545
gene id: 1547283:A9C19_RS02545
uniprot id: A0A1L3MN16
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1547283:A9C19 RS15695
gene id: 1547283:A9C19_RS15695
uniprot id: A0A1L3MUI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS17430
gene id: 1547283:A9C19_RS17430
uniprot id: A0A1L3MVE3
names: Similarity
messages: Belongs to the CdaR family.

1547283:A9C19 RS06700
gene id: 1547283:A9C19_RS06700
uniprot id: A0A1L3MQ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS15275
gene id: 1547283:A9C19_RS15275
uniprot id: A0A1L3MUD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1547283:A9C19 RS12500
gene id: 1547283:A9C19_RS12500
uniprot id: A0A1L3MT08
names: Similarity
messages: Belongs to the MoaD family.

1547283:A9C19 RS10255
gene id: 1547283:A9C19_RS10255
uniprot id: A0A1L3MRU0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1547283:A9C19 RS17385
gene id: 1547283:A9C19_RS17385
uniprot id: A0A1L3MVF0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS11415
gene id: 1547283:A9C19_RS11415
uniprot id: A0A1L3MSH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Essential protein that is required for a late step of 50S ribosomal subunit assembly. Has GTPase activity that is stimulated by interaction with the immature 50S ribosome subunit. Binds to the 23S rRNA. Required for the association of ribosomal proteins rplP and rpmA with the large subunit.
messages: Interacts with ctc. Interacts with the immature 50S ribosome subunit. 2 molecules of rbgA bind to one 50S subunit.
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1547283:A9C19 RS07320
gene id: 1547283:A9C19_RS07320
uniprot id: A0A1L3MQG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1547283:A9C19 RS19235
gene id: 1547283:A9C19_RS19235
uniprot id: A0A1L3MW95
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS18615
gene id: 1547283:A9C19_RS18615
uniprot id: A0A1L3MVZ8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1547283:A9C19 RS06180
gene id: 1547283:A9C19_RS06180
uniprot id: A0A1L3MPR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1547283:A9C19 RS04370
gene id: 1547283:A9C19_RS04370
uniprot id: A0A1L3MNV0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1547283:A9C19 RS11855
gene id: 1547283:A9C19_RS11855
uniprot id: A0A1L3MXL0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS13740
gene id: 1547283:A9C19_RS13740
uniprot id: A0A1L3MTL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS20920
gene id: 1547283:A9C19_RS20920
uniprot id: A0A1L3MWZ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS20530
gene id: 1547283:A9C19_RS20530
uniprot id: A0A1L3MXY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1547283:A9C19 RS19070
gene id: 1547283:A9C19_RS19070
uniprot id: A0A1L3MW61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1547283:A9C19 RS17650
gene id: 1547283:A9C19_RS17650
uniprot id: A0A1L3MVJ0
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS01000
gene id: 1547283:A9C19_RS01000
uniprot id: A0A1L3MM60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1547283:A9C19 RS07280
gene id: 1547283:A9C19_RS07280
uniprot id: A0A1L3MQB5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1547283:A9C19 RS18620
gene id: 1547283:A9C19_RS18620
uniprot id: A0A1L3MVY8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1547283:A9C19 RS18395
gene id: 1547283:A9C19_RS18395
uniprot id: A0A1L3MVX3
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS06110
gene id: 1547283:A9C19_RS06110
uniprot id: A0A1L3MPQ1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1547283:A9C19 RS11490
gene id: 1547283:A9C19_RS11490
uniprot id: A0A1L3MSM5
names: Similarity
messages: Belongs to the fabD family.

1547283:A9C19 RS13010
gene id: 1547283:A9C19_RS13010
uniprot id: A0A1L3MTA0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1547283:A9C19 RS11480
gene id: 1547283:A9C19_RS11480
uniprot id: A0A1L3MSG5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1547283:A9C19 RS05645
gene id: 1547283:A9C19_RS05645
uniprot id: A0A1L3MPH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1547283:A9C19 RS11375
gene id: 1547283:A9C19_RS11375
uniprot id: A0A1L3MSF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1547283:A9C19 RS02630
gene id: 1547283:A9C19_RS02630
uniprot id: A0A1L3MN03
names: Similarity
messages: Belongs to the peptidase C56 family.

1547283:A9C19 RS17120
gene id: 1547283:A9C19_RS17120
uniprot id: A0A1L3MV90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1547283:A9C19 RS22025
gene id: 1547283:A9C19_RS22025
uniprot id: A0A1L3MSJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

1547283:A9C19 RS04805
gene id: 1547283:A9C19_RS04805
uniprot id: A0A1L3MP03
names: Similarity
messages: Belongs to the UPF0173 family.

1547283:A9C19 RS06420
gene id: 1547283:A9C19_RS06420
uniprot id: A0A1L3MPX1
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS19400
gene id: 1547283:A9C19_RS19400
uniprot id: A0A1L3MWB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS10285
gene id: 1547283:A9C19_RS10285
uniprot id: A0A1L3MRU6
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1547283:A9C19 RS15505
gene id: 1547283:A9C19_RS15505
uniprot id: A0A1L3MUG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

1547283:A9C19 RS04860
gene id: 1547283:A9C19_RS04860
uniprot id: A0A1L3MP07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1547283:A9C19 RS06405
gene id: 1547283:A9C19_RS06405
uniprot id: A0A1L3MQ05
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1547283:A9C19 RS07060
gene id: 1547283:A9C19_RS07060
uniprot id: A0A1L3MQ78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1547283:A9C19 RS17060
gene id: 1547283:A9C19_RS17060
uniprot id: A0A1L3MV84
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS19670
gene id: 1547283:A9C19_RS19670
uniprot id: A0A1L3MWG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1547283:A9C19 RS11770
gene id: 1547283:A9C19_RS11770
uniprot id: A0A1L3MSM3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1547283:A9C19 RS18095
gene id: 1547283:A9C19_RS18095
uniprot id: A0A1L3MVQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1547283:A9C19 RS17665
gene id: 1547283:A9C19_RS17665
uniprot id: A0A1L3MVK5
names: Similarity
messages: Belongs to the UPF0435 family.

1547283:A9C19 RS00775
gene id: 1547283:A9C19_RS00775
uniprot id: A0A1L3MM31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1547283:A9C19 RS00500
gene id: 1547283:A9C19_RS00500
uniprot id: A0A1L3MLW9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS06185
gene id: 1547283:A9C19_RS06185
uniprot id: A0A1L3MPV2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1547283:A9C19 RS11910
gene id: 1547283:A9C19_RS11910
uniprot id: A0A1L3MSU3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1547283:A9C19 RS04400
gene id: 1547283:A9C19_RS04400
uniprot id: A0A1L3MP69
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS18835
gene id: 1547283:A9C19_RS18835
uniprot id: A0A1L3MW41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1547283:A9C19 RS16120
gene id: 1547283:A9C19_RS16120
uniprot id: A0A1L3MUR9
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1547283:A9C19 RS20650
gene id: 1547283:A9C19_RS20650
uniprot id: A0A1L3MWW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1547283:A9C19 RS03835
gene id: 1547283:A9C19_RS03835
uniprot id: A0A1L3MNL9
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS18270
gene id: 1547283:A9C19_RS18270
uniprot id: A0A1L3MVU4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1547283:A9C19 RS14120
gene id: 1547283:A9C19_RS14120
uniprot id: A0A1L3MXQ7
names: Similarity
messages: Belongs to the peptidase S16 family.

1547283:A9C19 RS14920
gene id: 1547283:A9C19_RS14920
uniprot id: A0A1L3MU62
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

1547283:A9C19 RS14405
gene id: 1547283:A9C19_RS14405
uniprot id: A0A1L3MTX0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1547283:A9C19 RS07820
gene id: 1547283:A9C19_RS07820
uniprot id: A0A1L3MQM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS10355
gene id: 1547283:A9C19_RS10355
uniprot id: A0A1L3MRV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1547283:A9C19 RS02000
gene id: 1547283:A9C19_RS02000
uniprot id: A0A1L3MMQ9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1547283:A9C19 RS19575
gene id: 1547283:A9C19_RS19575
uniprot id: A0A1L3MWF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1547283:A9C19 RS01510
gene id: 1547283:A9C19_RS01510
uniprot id: A0A1L3MX34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS19030
gene id: 1547283:A9C19_RS19030
uniprot id: A0A1L3MW62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1547283:A9C19 RS04190
gene id: 1547283:A9C19_RS04190
uniprot id: A0A1L3MNT3
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1547283:A9C19 RS20860
gene id: 1547283:A9C19_RS20860
uniprot id: A0A1L3MWY6
names: Subunit
messages: Homodimer.

1547283:A9C19 RS11175
gene id: 1547283:A9C19_RS11175
uniprot id: A0A1L3MSB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1547283:A9C19 RS12515
gene id: 1547283:A9C19_RS12515
uniprot id: A0A1L3MT06
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1547283:A9C19 RS05530
gene id: 1547283:A9C19_RS05530
uniprot id: A0A1L3MPD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS04885
gene id: 1547283:A9C19_RS04885
uniprot id: A0A1L3MX90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1547283:A9C19 RS16195
gene id: 1547283:A9C19_RS16195
uniprot id: A0A1L3MUS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1547283:A9C19 RS10745
gene id: 1547283:A9C19_RS10745
uniprot id: A0A1L3MXJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS14690
gene id: 1547283:A9C19_RS14690
uniprot id: A0A1L3MU20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS14880
gene id: 1547283:A9C19_RS14880
uniprot id: A0A1L3MU47
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1547283:A9C19 RS09840
gene id: 1547283:A9C19_RS09840
uniprot id: A0A1L3MRK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1547283:A9C19 RS11500
gene id: 1547283:A9C19_RS11500
uniprot id: A0A1L3MSG4
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

1547283:A9C19 RS20945
gene id: 1547283:A9C19_RS20945
uniprot id: A0A1L3MX08
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS19645
gene id: 1547283:A9C19_RS19645
uniprot id: A0A1L3MWG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1547283:A9C19 RS20605
gene id: 1547283:A9C19_RS20605
uniprot id: A0A1L3MWU8
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS02650
gene id: 1547283:A9C19_RS02650
uniprot id: A0A1L3MN18
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1547283:A9C19 RS05445
gene id: 1547283:A9C19_RS05445
uniprot id: A0A1L3MPC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.
messages: Membrane

1547283:A9C19 RS02250
gene id: 1547283:A9C19_RS02250
uniprot id: A0A1L3MMX9
names: Similarity
messages: Belongs to the HPr family.

1547283:A9C19 RS14005
gene id: 1547283:A9C19_RS14005
uniprot id: A0A1L3MTQ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS01010
gene id: 1547283:A9C19_RS01010
uniprot id: A0A1L3MMB0
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS04375
gene id: 1547283:A9C19_RS04375
uniprot id: A0A1L3MNV8
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS01920
gene id: 1547283:A9C19_RS01920
uniprot id: A0A1L3MX60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS13120
gene id: 1547283:A9C19_RS13120
uniprot id: A0A1L3MTB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1547283:A9C19 RS11515
gene id: 1547283:A9C19_RS11515
uniprot id: A0A1L3MSM0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1547283:A9C19 RS02840
gene id: 1547283:A9C19_RS02840
uniprot id: A0A1L3MX70
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS04745
gene id: 1547283:A9C19_RS04745
uniprot id: A0A1L3MP10
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1547283:A9C19 RS15605
gene id: 1547283:A9C19_RS15605
uniprot id: A0A1L3MUI9
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS02035
gene id: 1547283:A9C19_RS02035
uniprot id: A0A1L3MMT5
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1547283:A9C19 RS05425
gene id: 1547283:A9C19_RS05425
uniprot id: A0A1L3MPG9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1547283:A9C19 RS03815
gene id: 1547283:A9C19_RS03815
uniprot id: A0A1L3MNL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS13720
gene id: 1547283:A9C19_RS13720
uniprot id: A0A1L3MTL8
names: Similarity
names: Subcellular Location Annotation
messages: In the N-terminal section; belongs to the LXG family.
messages: Secreted

1547283:A9C19 RS14045
gene id: 1547283:A9C19_RS14045
uniprot id: A0A1L3MTR2
names: Similarity
messages: Belongs to the CdaR family.

1547283:A9C19 RS14080
gene id: 1547283:A9C19_RS14080
uniprot id: A0A1L3MTQ7
names: Cofactor
messages: Binds 1 FAD per subunit.

1547283:A9C19 RS20520
gene id: 1547283:A9C19_RS20520
uniprot id: A0A1L3MXY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS13290
gene id: 1547283:A9C19_RS13290
uniprot id: A0A1L3MTH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1547283:A9C19 RS00455
gene id: 1547283:A9C19_RS00455
uniprot id: A0A1L3MLZ7
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 14 family.
messages: Binds 1 Ca(2+) ion per subunit.

1547283:A9C19 RS11685
gene id: 1547283:A9C19_RS11685
uniprot id: A0A1L3MXJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1547283:A9C19 RS00130
gene id: 1547283:A9C19_RS00130
uniprot id: A0A1L3MX33
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS17880
gene id: 1547283:A9C19_RS17880
uniprot id: A0A1L3MVP3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1547283:A9C19 RS05635
gene id: 1547283:A9C19_RS05635
uniprot id: A0A1L3MPI4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1547283:A9C19 RS20255
gene id: 1547283:A9C19_RS20255
uniprot id: A0A1L3MWQ1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1547283:A9C19 RS04895
gene id: 1547283:A9C19_RS04895
uniprot id: A0A1L3MP28
names: Similarity
messages: Belongs to the citrate synthase family.

1547283:A9C19 RS19555
gene id: 1547283:A9C19_RS19555
uniprot id: A0A1L3MWE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1547283:A9C19 RS11570
gene id: 1547283:A9C19_RS11570
uniprot id: A0A1L3MXK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1547283:A9C19 RS11090
gene id: 1547283:A9C19_RS11090
uniprot id: A0A1L3MSE0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1547283:A9C19 RS04970
gene id: 1547283:A9C19_RS04970
uniprot id: A0A1L3MPA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1547283:A9C19 RS06130
gene id: 1547283:A9C19_RS06130
uniprot id: A0A1L3MPQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1547283:A9C19 RS15195
gene id: 1547283:A9C19_RS15195
uniprot id: A0A1L3MUA7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1547283:A9C19 RS17040
gene id: 1547283:A9C19_RS17040
uniprot id: A0A1L3MV77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS18310
gene id: 1547283:A9C19_RS18310
uniprot id: A0A1L3MVU2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1547283:A9C19 RS06045
gene id: 1547283:A9C19_RS06045
uniprot id: A0A1L3MPZ3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1547283:A9C19 RS08325
gene id: 1547283:A9C19_RS08325
uniprot id: A0A1L3MQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1547283:A9C19 RS19730
gene id: 1547283:A9C19_RS19730
uniprot id: A0A1L3MWI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1547283:A9C19 RS06955
gene id: 1547283:A9C19_RS06955
uniprot id: A0A1L3MQ47
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS12015
gene id: 1547283:A9C19_RS12015
uniprot id: A0A1L3MSP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1547283:A9C19 RS19750
gene id: 1547283:A9C19_RS19750
uniprot id: A0A1L3MWH2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1547283:A9C19 RS06115
gene id: 1547283:A9C19_RS06115
uniprot id: A0A1L3MPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1547283:A9C19 RS00160
gene id: 1547283:A9C19_RS00160
uniprot id: A0A1L3MLS1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1547283:A9C19 RS11095
gene id: 1547283:A9C19_RS11095
uniprot id: A0A1L3MSA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1547283:A9C19 RS12460
gene id: 1547283:A9C19_RS12460
uniprot id: A0A1L3MSX9
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS03780
gene id: 1547283:A9C19_RS03780
uniprot id: A0A1L3MNL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.
messages: Membrane

1547283:A9C19 RS20085
gene id: 1547283:A9C19_RS20085
uniprot id: A0A1L3MWN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS15770
gene id: 1547283:A9C19_RS15770
uniprot id: A0A1L3MXR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS11470
gene id: 1547283:A9C19_RS11470
uniprot id: A0A1L3MSI5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1547283:A9C19 RS11845
gene id: 1547283:A9C19_RS11845
uniprot id: A0A1L3MST2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1547283:A9C19 RS00235
gene id: 1547283:A9C19_RS00235
uniprot id: A0A1L3MLU3
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1547283:A9C19 RS04790
gene id: 1547283:A9C19_RS04790
uniprot id: A0A1L3MP00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1547283:A9C19 RS09295
gene id: 1547283:A9C19_RS09295
uniprot id: A0A1L3MRA1
names: Similarity
messages: Belongs to the IucA/IucC family.

1547283:A9C19 RS11030
gene id: 1547283:A9C19_RS11030
uniprot id: A0A1L3MS67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1547283:A9C19 RS00640
gene id: 1547283:A9C19_RS00640
uniprot id: A0A1L3MLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1547283:A9C19 RS18345
gene id: 1547283:A9C19_RS18345
uniprot id: A0A1L3MVV9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS11105
gene id: 1547283:A9C19_RS11105
uniprot id: A0A1L3MSC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1547283:A9C19 RS13490
gene id: 1547283:A9C19_RS13490
uniprot id: A0A1L3MTG1
names: Similarity
messages: Belongs to the MQO family.

1547283:A9C19 RS05345
gene id: 1547283:A9C19_RS05345
uniprot id: A0A1L3MPD2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS00245
gene id: 1547283:A9C19_RS00245
uniprot id: A0A1L3MM22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS12475
gene id: 1547283:A9C19_RS12475
uniprot id: A0A1L3MSZ0
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS10100
gene id: 1547283:A9C19_RS10100
uniprot id: A0A1L3MRZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1547283:A9C19 RS08870
gene id: 1547283:A9C19_RS08870
uniprot id: A0A1L3MR51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1547283:A9C19 RS14485
gene id: 1547283:A9C19_RS14485
uniprot id: A0A1L3MTX9
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1547283:A9C19 RS06400
gene id: 1547283:A9C19_RS06400
uniprot id: A0A1L3MPV5
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

1547283:A9C19 RS07620
gene id: 1547283:A9C19_RS07620
uniprot id: A0A1L3MQI2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1547283:A9C19 RS13115
gene id: 1547283:A9C19_RS13115
uniprot id: A0A1L3MTB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1547283:A9C19 RS04160
gene id: 1547283:A9C19_RS04160
uniprot id: A0A1L3MNQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS18105
gene id: 1547283:A9C19_RS18105
uniprot id: A0A1L3MVR6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS13340
gene id: 1547283:A9C19_RS13340
uniprot id: A0A1L3MTI7
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS02005
gene id: 1547283:A9C19_RS02005
uniprot id: A0A1L3MMR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS12535
gene id: 1547283:A9C19_RS12535
uniprot id: A0A1L3MXM0
names: Similarity
messages: Belongs to the UPF0180 family.

1547283:A9C19 RS02570
gene id: 1547283:A9C19_RS02570
uniprot id: A0A1L3MN38
names: Similarity
messages: Belongs to the peptidase C40 family.

1547283:A9C19 RS09385
gene id: 1547283:A9C19_RS09385
uniprot id: A0A1L3MRE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SscA family.
messages: Membrane

1547283:A9C19 RS11335
gene id: 1547283:A9C19_RS11335
uniprot id: A0A1L3MSD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1547283:A9C19 RS05005
gene id: 1547283:A9C19_RS05005
uniprot id: A0A1L3MP52
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1547283:A9C19 RS02875
gene id: 1547283:A9C19_RS02875
uniprot id: A0A1L3MN40
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1547283:A9C19 RS15150
gene id: 1547283:A9C19_RS15150
uniprot id: A0A1L3MUA4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1547283:A9C19 RS04520
gene id: 1547283:A9C19_RS04520
uniprot id: A0A1L3MNV7
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1547283:A9C19 RS06210
gene id: 1547283:A9C19_RS06210
uniprot id: A0A1L3MPS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1547283:A9C19 RS12980
gene id: 1547283:A9C19_RS12980
uniprot id: A0A1L3MT74
names: Similarity
messages: Belongs to the MotB family.

1547283:A9C19 RS20030
gene id: 1547283:A9C19_RS20030
uniprot id: A0A1L3MWL6
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation.

1547283:A9C19 RS17910
gene id: 1547283:A9C19_RS17910
uniprot id: A0A1L3MVN4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1547283:A9C19 RS20390
gene id: 1547283:A9C19_RS20390
uniprot id: A0A1L3MWS3
names: Similarity
messages: Belongs to the ParB family.

1547283:A9C19 RS04635
gene id: 1547283:A9C19_RS04635
uniprot id: A0A1L3MNZ7
names: Similarity
messages: Belongs to the histone deacetylase family.

1547283:A9C19 RS20340
gene id: 1547283:A9C19_RS20340
uniprot id: A0A1L3MWR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1547283:A9C19 RS18425
gene id: 1547283:A9C19_RS18425
uniprot id: A0A1L3MVX6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1547283:A9C19 RS05675
gene id: 1547283:A9C19_RS05675
uniprot id: A0A1L3MPG4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1547283:A9C19 RS07125
gene id: 1547283:A9C19_RS07125
uniprot id: A0A1L3MQ88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1547283:A9C19 RS12240
gene id: 1547283:A9C19_RS12240
uniprot id: A0A1L3MST7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SscA family.
messages: Membrane

1547283:A9C19 RS00780
gene id: 1547283:A9C19_RS00780
uniprot id: A0A1L3MM17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1547283:A9C19 RS01090
gene id: 1547283:A9C19_RS01090
uniprot id: A0A1L3MM76
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

1547283:A9C19 RS07760
gene id: 1547283:A9C19_RS07760
uniprot id: A0A1L3MQV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1547283:A9C19 RS08455
gene id: 1547283:A9C19_RS08455
uniprot id: A0A1L3MQX6
names: Similarity
messages: Belongs to the peptidase C40 family.

1547283:A9C19 RS03665
gene id: 1547283:A9C19_RS03665
uniprot id: A0A1L3MNJ4
names: Similarity
messages: Belongs to the methyltransferase superfamily. PrmA family.

1547283:A9C19 RS04905
gene id: 1547283:A9C19_RS04905
uniprot id: A0A1L3MP36
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1547283:A9C19 RS01620
gene id: 1547283:A9C19_RS01620
uniprot id: A0A1L3MMQ7
names: Similarity
messages: Belongs to the TelA family.

1547283:A9C19 RS09465
gene id: 1547283:A9C19_RS09465
uniprot id: A0A1L3MRC5
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

1547283:A9C19 RS02305
gene id: 1547283:A9C19_RS02305
uniprot id: A0A1L3MMZ1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1547283:A9C19 RS06990
gene id: 1547283:A9C19_RS06990
uniprot id: A0A1L3MQ72
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1547283:A9C19 RS11425
gene id: 1547283:A9C19_RS11425
uniprot id: A0A1L3MSG6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1547283:A9C19 RS13040
gene id: 1547283:A9C19_RS13040
uniprot id: A0A1L3MT99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

1547283:A9C19 RS02915
gene id: 1547283:A9C19_RS02915
uniprot id: A0A1L3MN79
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1547283:A9C19 RS20305
gene id: 1547283:A9C19_RS20305
uniprot id: A0A1L3MXX7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1547283:A9C19 RS19570
gene id: 1547283:A9C19_RS19570
uniprot id: A0A1L3MWE6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1547283:A9C19 RS01900
gene id: 1547283:A9C19_RS01900
uniprot id: A0A1L3MMN7
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS00735
gene id: 1547283:A9C19_RS00735
uniprot id: A0A1L3MM55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1547283:A9C19 RS03320
gene id: 1547283:A9C19_RS03320
uniprot id: A0A1L3MX69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1547283:A9C19 RS01885
gene id: 1547283:A9C19_RS01885
uniprot id: A0A1L3MMV4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1547283:A9C19 RS03790
gene id: 1547283:A9C19_RS03790
uniprot id: A0A1L3MNL3
names: Similarity
messages: Belongs to the CapA family.

1547283:A9C19 RS10140
gene id: 1547283:A9C19_RS10140
uniprot id: A0A1L3MRS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1547283:A9C19 RS05070
gene id: 1547283:A9C19_RS05070
uniprot id: A0A1L3MP73
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS04710
gene id: 1547283:A9C19_RS04710
uniprot id: A0A1L3MNY9
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1547283:A9C19 RS20950
gene id: 1547283:A9C19_RS20950
uniprot id: A0A1L3MX06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EsaA family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS05355
gene id: 1547283:A9C19_RS05355
uniprot id: A0A1L3MPA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS02050
gene id: 1547283:A9C19_RS02050
uniprot id: A0A1L3MMQ0
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1547283:A9C19 RS17125
gene id: 1547283:A9C19_RS17125
uniprot id: A0A1L3MV99
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1547283:A9C19 RS11700
gene id: 1547283:A9C19_RS11700
uniprot id: A0A1L3MSL2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS07665
gene id: 1547283:A9C19_RS07665
uniprot id: A0A1L3MQH9
names: Similarity
messages: Belongs to the TrpC family.

1547283:A9C19 RS12830
gene id: 1547283:A9C19_RS12830
uniprot id: A0A1L3MT97
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS13035
gene id: 1547283:A9C19_RS13035
uniprot id: A0A1L3MT94
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1547283:A9C19 RS11730
gene id: 1547283:A9C19_RS11730
uniprot id: A0A1L3MSL8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1547283:A9C19 RS02055
gene id: 1547283:A9C19_RS02055
uniprot id: A0A1L3MMR7
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1547283:A9C19 RS07050
gene id: 1547283:A9C19_RS07050
uniprot id: A0A1L3MQ76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1547283:A9C19 RS06380
gene id: 1547283:A9C19_RS06380
uniprot id: A0A1L3MPV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1547283:A9C19 RS17775
gene id: 1547283:A9C19_RS17775
uniprot id: A0A1L3MVM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS04540
gene id: 1547283:A9C19_RS04540
uniprot id: A0A1L3MNY3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS17480
gene id: 1547283:A9C19_RS17480
uniprot id: A0A1L3MVF8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1547283:A9C19 RS19635
gene id: 1547283:A9C19_RS19635
uniprot id: A0A1L3MWL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1547283:A9C19 RS15155
gene id: 1547283:A9C19_RS15155
uniprot id: A0A1L3MU96
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1547283:A9C19 RS14360
gene id: 1547283:A9C19_RS14360
uniprot id: A0A1L3MTY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1547283:A9C19 RS15720
gene id: 1547283:A9C19_RS15720
uniprot id: A0A1L3MUR0
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1547283:A9C19 RS12610
gene id: 1547283:A9C19_RS12610
uniprot id: A0A1L3MT33
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1547283:A9C19 RS02970
gene id: 1547283:A9C19_RS02970
uniprot id: A0A1L3MN64
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1547283:A9C19 RS17770
gene id: 1547283:A9C19_RS17770
uniprot id: A0A1L3MVJ8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1547283:A9C19 RS05775
gene id: 1547283:A9C19_RS05775
uniprot id: A0A1L3MXB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1547283:A9C19 RS00950
gene id: 1547283:A9C19_RS00950
uniprot id: A0A1L3MM86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1547283:A9C19 RS15580
gene id: 1547283:A9C19_RS15580
uniprot id: A0A1L3MUJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1547283:A9C19 RS11715
gene id: 1547283:A9C19_RS11715
uniprot id: A0A1L3MSL3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1547283:A9C19 RS04705
gene id: 1547283:A9C19_RS04705
uniprot id: A0A1L3MP41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1547283:A9C19 RS18455
gene id: 1547283:A9C19_RS18455
uniprot id: A0A1L3MVX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1547283:A9C19 RS03410
gene id: 1547283:A9C19_RS03410
uniprot id: A0A1L3MNE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS01355
gene id: 1547283:A9C19_RS01355
uniprot id: A0A1L3MMC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1547283:A9C19 RS15495
gene id: 1547283:A9C19_RS15495
uniprot id: A0A1L3MUF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1547283:A9C19 RS04960
gene id: 1547283:A9C19_RS04960
uniprot id: A0A1L3MP57
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1547283:A9C19 RS02385
gene id: 1547283:A9C19_RS02385
uniprot id: A0A1L3MMX3
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS08495
gene id: 1547283:A9C19_RS08495
uniprot id: A0A1L3MQV5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS04510
gene id: 1547283:A9C19_RS04510
uniprot id: A0A1L3MP87
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS19920
gene id: 1547283:A9C19_RS19920
uniprot id: A0A1L3MWJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1547283:A9C19 RS01435
gene id: 1547283:A9C19_RS01435
uniprot id: A0A1L3MMH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS12795
gene id: 1547283:A9C19_RS12795
uniprot id: A0A1L3MT60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1547283:A9C19 RS01700
gene id: 1547283:A9C19_RS01700
uniprot id: A0A1L3MMI8
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

1547283:A9C19 RS12495
gene id: 1547283:A9C19_RS12495
uniprot id: A0A1L3MSZ7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1547283:A9C19 RS05100
gene id: 1547283:A9C19_RS05100
uniprot id: A0A1L3MP67
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1547283:A9C19 RS07345
gene id: 1547283:A9C19_RS07345
uniprot id: A0A1L3MQC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1547283:A9C19 RS14940
gene id: 1547283:A9C19_RS14940
uniprot id: A0A1L3MUC3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1547283:A9C19 RS04180
gene id: 1547283:A9C19_RS04180
uniprot id: A0A1L3MNQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1547283:A9C19 RS01735
gene id: 1547283:A9C19_RS01735
uniprot id: A0A1L3MMJ2
names: Similarity
messages: Belongs to the IMPACT family.

1547283:A9C19 RS10805
gene id: 1547283:A9C19_RS10805
uniprot id: A0A1L3MS47
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1547283:A9C19 RS13745
gene id: 1547283:A9C19_RS13745
uniprot id: A0A1L3MTM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS12480
gene id: 1547283:A9C19_RS12480
uniprot id: A0A1L3MSY6
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

1547283:A9C19 RS04915
gene id: 1547283:A9C19_RS04915
uniprot id: A0A1L3MP15
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS05760
gene id: 1547283:A9C19_RS05760
uniprot id: A0A1L3MPN0
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS19615
gene id: 1547283:A9C19_RS19615
uniprot id: A0A1L3MWF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1547283:A9C19 RS05240
gene id: 1547283:A9C19_RS05240
uniprot id: A0A1L3MP94
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1547283:A9C19 RS08900
gene id: 1547283:A9C19_RS08900
uniprot id: A0A1L3MR90
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS08110
gene id: 1547283:A9C19_RS08110
uniprot id: A0A1L3MQT1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1547283:A9C19 RS07045
gene id: 1547283:A9C19_RS07045
uniprot id: A0A1L3MQ75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1547283:A9C19 RS13615
gene id: 1547283:A9C19_RS13615
uniprot id: A0A1L3MTJ6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1547283:A9C19 RS20350
gene id: 1547283:A9C19_RS20350
uniprot id: A0A1L3MWR1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

1547283:A9C19 RS15405
gene id: 1547283:A9C19_RS15405
uniprot id: A0A1L3MUE4
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1547283:A9C19 RS12365
gene id: 1547283:A9C19_RS12365
uniprot id: A0A1L3MT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS11590
gene id: 1547283:A9C19_RS11590
uniprot id: A0A1L3MSI7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS05395
gene id: 1547283:A9C19_RS05395
uniprot id: A0A1L3MPD3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1547283:A9C19 RS18275
gene id: 1547283:A9C19_RS18275
uniprot id: A0A1L3MW06
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1547283:A9C19 RS11475
gene id: 1547283:A9C19_RS11475
uniprot id: A0A1L3MXQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1547283:A9C19 RS16980
gene id: 1547283:A9C19_RS16980
uniprot id: A0A1L3MV49
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1547283:A9C19 RS05080
gene id: 1547283:A9C19_RS05080
uniprot id: A0A1L3MPC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1547283:A9C19 RS10820
gene id: 1547283:A9C19_RS10820
uniprot id: A0A1L3MS24
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1547283:A9C19 RS18360
gene id: 1547283:A9C19_RS18360
uniprot id: A0A1L3MVW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07490
gene id: 1547283:A9C19_RS07490
uniprot id: A0A1L3MQG3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.
messages: Homodimer.
messages: The N-terminal domain has binding sites for ComK and probably for unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1547283:A9C19 RS02950
gene id: 1547283:A9C19_RS02950
uniprot id: A0A1L3MNE1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1547283:A9C19 RS20000
gene id: 1547283:A9C19_RS20000
uniprot id: A0A1L3MWJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1547283:A9C19 RS08135
gene id: 1547283:A9C19_RS08135
uniprot id: A0A1L3MQR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS10405
gene id: 1547283:A9C19_RS10405
uniprot id: A0A1L3MRZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07600
gene id: 1547283:A9C19_RS07600
uniprot id: A0A1L3MQL9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1547283:A9C19 RS22520
gene id: 1547283:A9C19_RS22520
uniprot id: A0A1L3MMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1547283:A9C19 RS12950
gene id: 1547283:A9C19_RS12950
uniprot id: A0A1L3MT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1547283:A9C19 RS09690
gene id: 1547283:A9C19_RS09690
uniprot id: A0A1L3MXH9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1547283:A9C19 RS00510
gene id: 1547283:A9C19_RS00510
uniprot id: A0A1L3MLX0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS14545
gene id: 1547283:A9C19_RS14545
uniprot id: A0A1L3MTY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1547283:A9C19 RS06195
gene id: 1547283:A9C19_RS06195
uniprot id: A0A1L3MQ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1547283:A9C19 RS11865
gene id: 1547283:A9C19_RS11865
uniprot id: A0A1L3MXL2
names: Similarity
messages: Belongs to the transpeptidase family.

1547283:A9C19 RS19665
gene id: 1547283:A9C19_RS19665
uniprot id: A0A1L3MWF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1547283:A9C19 RS18390
gene id: 1547283:A9C19_RS18390
uniprot id: A0A1L3MVX5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

1547283:A9C19 RS18950
gene id: 1547283:A9C19_RS18950
uniprot id: A0A1L3MXW4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

1547283:A9C19 RS03220
gene id: 1547283:A9C19_RS03220
uniprot id: A0A1L3MNC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1547283:A9C19 RS05010
gene id: 1547283:A9C19_RS05010
uniprot id: A0A1L3MP64
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1547283:A9C19 RS08770
gene id: 1547283:A9C19_RS08770
uniprot id: A0A1L3MR53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1547283:A9C19 RS12185
gene id: 1547283:A9C19_RS12185
uniprot id: A0A1L3MSS6
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS03095
gene id: 1547283:A9C19_RS03095
uniprot id: A0A1L3MN84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS02540
gene id: 1547283:A9C19_RS02540
uniprot id: A0A1L3MMZ9
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

1547283:A9C19 RS00215
gene id: 1547283:A9C19_RS00215
uniprot id: A0A1L3MLS8
names: Subcellular Location Annotation
messages: Cell membrane

1547283:A9C19 RS00095
gene id: 1547283:A9C19_RS00095
uniprot id: A0A1L3MX10
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1547283:A9C19 RS04450
gene id: 1547283:A9C19_RS04450
uniprot id: A0A1L3MNZ6
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS11315
gene id: 1547283:A9C19_RS11315
uniprot id: A0A1L3MSF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS18635
gene id: 1547283:A9C19_RS18635
uniprot id: A0A1L3MW07
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS15105
gene id: 1547283:A9C19_RS15105
uniprot id: A0A1L3MXQ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1547283:A9C19 RS06295
gene id: 1547283:A9C19_RS06295
uniprot id: A0A1L3MPU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS06980
gene id: 1547283:A9C19_RS06980
uniprot id: A0A1L3MQ70
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1547283:A9C19 RS18470
gene id: 1547283:A9C19_RS18470
uniprot id: A0A1L3MVY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1547283:A9C19 RS13840
gene id: 1547283:A9C19_RS13840
uniprot id: A0A1L3MTN8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS15510
gene id: 1547283:A9C19_RS15510
uniprot id: A0A1L3MUH8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1547283:A9C19 RS20890
gene id: 1547283:A9C19_RS20890
uniprot id: A0A1L3MWZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1547283:A9C19 RS05925
gene id: 1547283:A9C19_RS05925
uniprot id: A0A1L3MPQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1547283:A9C19 RS20185
gene id: 1547283:A9C19_RS20185
uniprot id: A0A1L3MWP0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1547283:A9C19 RS11505
gene id: 1547283:A9C19_RS11505
uniprot id: A0A1L3MSG3
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1547283:A9C19 RS07270
gene id: 1547283:A9C19_RS07270
uniprot id: A0A1L3MQB6
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

1547283:A9C19 RS05320
gene id: 1547283:A9C19_RS05320
uniprot id: A0A1L3MPA8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1547283:A9C19 RS03090
gene id: 1547283:A9C19_RS03090
uniprot id: A0A1L3MX58
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1547283:A9C19 RS10815
gene id: 1547283:A9C19_RS10815
uniprot id: A0A1L3MS38
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1547283:A9C19 RS09875
gene id: 1547283:A9C19_RS09875
uniprot id: A0A1L3MRV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS08865
gene id: 1547283:A9C19_RS08865
uniprot id: A0A1L3MR61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1547283:A9C19 RS11650
gene id: 1547283:A9C19_RS11650
uniprot id: A0A1L3MSN7
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1547283:A9C19 RS05525
gene id: 1547283:A9C19_RS05525
uniprot id: A0A1L3MPE3
names: Similarity
messages: Belongs to the GSP E family.

1547283:A9C19 RS18860
gene id: 1547283:A9C19_RS18860
uniprot id: A0A1L3MW44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1547283:A9C19 RS12035
gene id: 1547283:A9C19_RS12035
uniprot id: A0A1L3MSQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

1547283:A9C19 RS07640
gene id: 1547283:A9C19_RS07640
uniprot id: A0A1L3MQH5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1547283:A9C19 RS09290
gene id: 1547283:A9C19_RS09290
uniprot id: A0A1L3MRK6
names: Similarity
messages: Belongs to the IucA/IucC family.

1547283:A9C19 RS19860
gene id: 1547283:A9C19_RS19860
uniprot id: A0A1L3MWI9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1547283:A9C19 RS00365
gene id: 1547283:A9C19_RS00365
uniprot id: A0A1L3MM42
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

1547283:A9C19 RS19545
gene id: 1547283:A9C19_RS19545
uniprot id: A0A1L3MWE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1547283:A9C19 RS09650
gene id: 1547283:A9C19_RS09650
uniprot id: A0A1L3MRH6
names: Similarity
names: Subcellular Location Annotation
messages: In the N-terminal section; belongs to the LXG family.
messages: Secreted

1547283:A9C19 RS05735
gene id: 1547283:A9C19_RS05735
uniprot id: A0A1L3MPI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS00740
gene id: 1547283:A9C19_RS00740
uniprot id: A0A1L3MM19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1547283:A9C19 RS08645
gene id: 1547283:A9C19_RS08645
uniprot id: A0A1L3MR21
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1547283:A9C19 RS05065
gene id: 1547283:A9C19_RS05065
uniprot id: A0A1L3MP90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1547283:A9C19 RS18420
gene id: 1547283:A9C19_RS18420
uniprot id: A0A1L3MVY1
names: Similarity
messages: Belongs to the GARS family.

1547283:A9C19 RS08845
gene id: 1547283:A9C19_RS08845
uniprot id: A0A1L3MR78
names: Similarity
messages: Belongs to the peptidase S13 family.

1547283:A9C19 RS02095
gene id: 1547283:A9C19_RS02095
uniprot id: A0A1L3MX74
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1547283:A9C19 RS17615
gene id: 1547283:A9C19_RS17615
uniprot id: A0A1L3MVG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Membrane

1547283:A9C19 RS11830
gene id: 1547283:A9C19_RS11830
uniprot id: A0A1L3MSP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1547283:A9C19 RS17255
gene id: 1547283:A9C19_RS17255
uniprot id: A0A1L3MVB8
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS19470
gene id: 1547283:A9C19_RS19470
uniprot id: A0A1L3MWC4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1547283:A9C19 RS00850
gene id: 1547283:A9C19_RS00850
uniprot id: A0A1L3MM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1547283:A9C19 RS12720
gene id: 1547283:A9C19_RS12720
uniprot id: A0A1L3MXL9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1547283:A9C19 RS01670
gene id: 1547283:A9C19_RS01670
uniprot id: A0A1L3MMI0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1547283:A9C19 RS02225
gene id: 1547283:A9C19_RS02225
uniprot id: A0A1L3MMV0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1547283:A9C19 RS07795
gene id: 1547283:A9C19_RS07795
uniprot id: A0A1L3MQL6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1547283:A9C19 RS11180
gene id: 1547283:A9C19_RS11180
uniprot id: A0A1L3MS95
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1547283:A9C19 RS13365
gene id: 1547283:A9C19_RS13365
uniprot id: A0A1L3MTF3
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1547283:A9C19 RS04925
gene id: 1547283:A9C19_RS04925
uniprot id: A0A1L3MP32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1547283:A9C19 RS20495
gene id: 1547283:A9C19_RS20495
uniprot id: A0A1L3MXX9
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS00585
gene id: 1547283:A9C19_RS00585
uniprot id: A0A1L3MLZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1547283:A9C19 RS18435
gene id: 1547283:A9C19_RS18435
uniprot id: A0A1L3MVX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1547283:A9C19 RS11710
gene id: 1547283:A9C19_RS11710
uniprot id: A0A1L3MSK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1547283:A9C19 RS15015
gene id: 1547283:A9C19_RS15015
uniprot id: A0A1L3MU95
names: Similarity
messages: Belongs to the ThiD family.

1547283:A9C19 RS18305
gene id: 1547283:A9C19_RS18305
uniprot id: A0A1L3MVU1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1547283:A9C19 RS15500
gene id: 1547283:A9C19_RS15500
uniprot id: A0A1L3MUG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1547283:A9C19 RS13575
gene id: 1547283:A9C19_RS13575
uniprot id: A0A1L3MTM5
names: Similarity
messages: Belongs to the transpeptidase family.

1547283:A9C19 RS06845
gene id: 1547283:A9C19_RS06845
uniprot id: A0A1L3MQ82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1547283:A9C19 RS18430
gene id: 1547283:A9C19_RS18430
uniprot id: A0A1L3MW30
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1547283:A9C19 RS12045
gene id: 1547283:A9C19_RS12045
uniprot id: A0A1L3MSW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1547283:A9C19 RS10350
gene id: 1547283:A9C19_RS10350
uniprot id: A0A1L3MRY1
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS13025
gene id: 1547283:A9C19_RS13025
uniprot id: A0A1L3MTE2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type IV subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
messages: Has no RuBP-carboxylation activity.
messages: Homodimer.

1547283:A9C19 RS01330
gene id: 1547283:A9C19_RS01330
uniprot id: A0A1L3MMB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS04060
gene id: 1547283:A9C19_RS04060
uniprot id: A0A1L3MX72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1547283:A9C19 RS08630
gene id: 1547283:A9C19_RS08630
uniprot id: A0A1L3MQX7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1547283:A9C19 RS11605
gene id: 1547283:A9C19_RS11605
uniprot id: A0A1L3MSK4
names: Similarity
messages: Belongs to the RemA family.

1547283:A9C19 RS09430
gene id: 1547283:A9C19_RS09430
uniprot id: A0A1L3MRD0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1547283:A9C19 RS05115
gene id: 1547283:A9C19_RS05115
uniprot id: A0A1L3MP98
names: Similarity
messages: Belongs to the thioredoxin family.

1547283:A9C19 RS03405
gene id: 1547283:A9C19_RS03405
uniprot id: A0A1L3MNQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS07870
gene id: 1547283:A9C19_RS07870
uniprot id: A0A1L3MQX4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS05855
gene id: 1547283:A9C19_RS05855
uniprot id: A0A1L3MPM7
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1547283:A9C19 RS18070
gene id: 1547283:A9C19_RS18070
uniprot id: A0A1L3MVQ2
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1547283:A9C19 RS09850
gene id: 1547283:A9C19_RS09850
uniprot id: A0A1L3MRM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1547283:A9C19 RS06435
gene id: 1547283:A9C19_RS06435
uniprot id: A0A1L3MPX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1547283:A9C19 RS03430
gene id: 1547283:A9C19_RS03430
uniprot id: A0A1L3MNE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS20615
gene id: 1547283:A9C19_RS20615
uniprot id: A0A1L3MWV6
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS02800
gene id: 1547283:A9C19_RS02800
uniprot id: A0A1L3MN34
names: Similarity
messages: Belongs to the EamA transporter family.

1547283:A9C19 RS09175
gene id: 1547283:A9C19_RS09175
uniprot id: A0A1L3MRA2
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

1547283:A9C19 RS03810
gene id: 1547283:A9C19_RS03810
uniprot id: A0A1L3MNL2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS06500
gene id: 1547283:A9C19_RS06500
uniprot id: A0A1L3MPY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1547283:A9C19 RS20330
gene id: 1547283:A9C19_RS20330
uniprot id: A0A1L3MWP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1547283:A9C19 RS10015
gene id: 1547283:A9C19_RS10015
uniprot id: A0A1L3MRN6
names: Subcellular Location Annotation
messages: Cytoplasm

1547283:A9C19 RS10940
gene id: 1547283:A9C19_RS10940
uniprot id: A0A1L3MSB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1547283:A9C19 RS12540
gene id: 1547283:A9C19_RS12540
uniprot id: A0A1L3MT09
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
messages: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.

1547283:A9C19 RS09425
gene id: 1547283:A9C19_RS09425
uniprot id: A0A1L3MXF5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1547283:A9C19 RS06925
gene id: 1547283:A9C19_RS06925
uniprot id: A0A1L3MQE5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1547283:A9C19 RS11805
gene id: 1547283:A9C19_RS11805
uniprot id: A0A1L3MSN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1547283:A9C19 RS04210
gene id: 1547283:A9C19_RS04210
uniprot id: A0A1L3MNQ6
names: Similarity
messages: Belongs to the Dps family.

1547283:A9C19 RS07405
gene id: 1547283:A9C19_RS07405
uniprot id: A0A1L3MQD6
names: Subcellular Location Annotation
messages: Membrane

1547283:A9C19 RS09555
gene id: 1547283:A9C19_RS09555
uniprot id: A0A1L3MNI1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1547283:A9C19 RS17420
gene id: 1547283:A9C19_RS17420
uniprot id: A0A1L3MVE5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1547283:A9C19 RS11945
gene id: 1547283:A9C19_RS11945
uniprot id: A0A1L3MSQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1547283:A9C19 RS07445
gene id: 1547283:A9C19_RS07445
uniprot id: A0A1L3MQN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1547283:A9C19 RS07495
gene id: 1547283:A9C19_RS07495
uniprot id: A0A1L3MQJ4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1547283:A9C19 RS15200
gene id: 1547283:A9C19_RS15200
uniprot id: A0A1L3MUB4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1547283:A9C19 RS19495
gene id: 1547283:A9C19_RS19495
uniprot id: A0A1L3MWD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1547283:A9C19 RS09260
gene id: 1547283:A9C19_RS09260
uniprot id: A0A1L3MRD8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1547283:A9C19 RS15070
gene id: 1547283:A9C19_RS15070
uniprot id: A0A1L3MU98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1547283:A9C19 RS20905
gene id: 1547283:A9C19_RS20905
uniprot id: A0A1L3MX14
names: Subcellular Location Annotation
messages: Membrane