1543721:AAY24 RS16305
gene id: 1543721:AAY24_RS16305
uniprot id: A0A0F7JZC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS17610
gene id: 1543721:AAY24_RS17610
uniprot id: A0A0F7K4E7
names: Subcellular Location Annotation
messages: Cytoplasm

1543721:AAY24 RS09625
gene id: 1543721:AAY24_RS09625
uniprot id: A0A0F7JVL2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1543721:AAY24 RS01840
gene id: 1543721:AAY24_RS01840
uniprot id: A0A0F7JUN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1543721:AAY24 RS01295
gene id: 1543721:AAY24_RS01295
uniprot id: A0A0F7JV45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1543721:AAY24 RS14610
gene id: 1543721:AAY24_RS14610
uniprot id: A0A0F7K1D5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1543721:AAY24 RS08325
gene id: 1543721:AAY24_RS08325
uniprot id: A0A0F7JYK2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS09220
gene id: 1543721:AAY24_RS09220
uniprot id: A0A0F7JXS6
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1543721:AAY24 RS03945
gene id: 1543721:AAY24_RS03945
uniprot id: A0A0F7JXX6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1543721:AAY24 RS01075
gene id: 1543721:AAY24_RS01075
uniprot id: A0A0F7JX48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS16380
gene id: 1543721:AAY24_RS16380
uniprot id: A0A0F7K379
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS07030
gene id: 1543721:AAY24_RS07030
uniprot id: A0A0F7JZ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1543721:AAY24 RS10880
gene id: 1543721:AAY24_RS10880
uniprot id: A0A0F7JZL7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1543721:AAY24 RS14265
gene id: 1543721:AAY24_RS14265
uniprot id: A0A0F7K329
names: Similarity
messages: Belongs to the UPF0250 family.

1543721:AAY24 RS15455
gene id: 1543721:AAY24_RS15455
uniprot id: A0A0F7K3K8
names: Subcellular Location Annotation
messages: Mitochondrion

1543721:AAY24 RS14860
gene id: 1543721:AAY24_RS14860
uniprot id: A0A0F7K2I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1543721:AAY24 RS04130
gene id: 1543721:AAY24_RS04130
uniprot id: A0A0F7JXZ0
names: Subcellular Location Annotation
messages: Nucleus

1543721:AAY24 RS03120
gene id: 1543721:AAY24_RS03120
uniprot id: A0A0F7JXW0
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1543721:AAY24 RS01630
gene id: 1543721:AAY24_RS01630
uniprot id: A0A0F7K287
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
messages: Cytoplasm
messages: Homotetramer.

1543721:AAY24 RS03370
gene id: 1543721:AAY24_RS03370
uniprot id: A0A0F7JVH1
names: Similarity
messages: Belongs to the MEMO1 family.

1543721:AAY24 RS03795
gene id: 1543721:AAY24_RS03795
uniprot id: A0A0F7JVN5
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1543721:AAY24 RS15560
gene id: 1543721:AAY24_RS15560
uniprot id: A0A0F7K1V4
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1543721:AAY24 RS09355
gene id: 1543721:AAY24_RS09355
uniprot id: A0A0F7JXV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1543721:AAY24 RS10425
gene id: 1543721:AAY24_RS10425
uniprot id: A0A0F7JZE4
names: Similarity
messages: Belongs to the RutC family.

1543721:AAY24 RS09950
gene id: 1543721:AAY24_RS09950
uniprot id: A0A0F7JZA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1543721:AAY24 RS10430
gene id: 1543721:AAY24_RS10430
uniprot id: A0A0F7K0M1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1543721:AAY24 RS12395
gene id: 1543721:AAY24_RS12395
uniprot id: A0A0F7K087
names: Similarity
messages: Belongs to the peptidase C40 family.

1543721:AAY24 RS11945
gene id: 1543721:AAY24_RS11945
uniprot id: A0A0F7JWN8
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1543721:AAY24 RS16505
gene id: 1543721:AAY24_RS16505
uniprot id: A0A0F7K391
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS10825
gene id: 1543721:AAY24_RS10825
uniprot id: A0A0F7K0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1543721:AAY24 RS08170
gene id: 1543721:AAY24_RS08170
uniprot id: A0A0F7K070
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1543721:AAY24 RS05655
gene id: 1543721:AAY24_RS05655
uniprot id: A0A0F7JTQ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS10225
gene id: 1543721:AAY24_RS10225
uniprot id: A0A0F7JY97
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1543721:AAY24 RS05435
gene id: 1543721:AAY24_RS05435
uniprot id: A0A0F7JWX8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS09750
gene id: 1543721:AAY24_RS09750
uniprot id: A0A0F7JY30
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1543721:AAY24 RS02700
gene id: 1543721:AAY24_RS02700
uniprot id: A0A0F7JXB5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS05245
gene id: 1543721:AAY24_RS05245
uniprot id: A0A0F7JYB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1543721:AAY24 RS08625
gene id: 1543721:AAY24_RS08625
uniprot id: A0A0F7JZK6
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1543721:AAY24 RS14590
gene id: 1543721:AAY24_RS14590
uniprot id: A0A0F7K2E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1543721:AAY24 RS13915
gene id: 1543721:AAY24_RS13915
uniprot id: A0A0F7JXV0
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1543721:AAY24 RS04365
gene id: 1543721:AAY24_RS04365
uniprot id: A0A0F7JYJ6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1543721:AAY24 RS01625
gene id: 1543721:AAY24_RS01625
uniprot id: A0A0F7JWS9
names: Similarity
messages: Belongs to the FwdC/FmdC family.

1543721:AAY24 RS17650
gene id: 1543721:AAY24_RS17650
uniprot id: A0A0F7K3N5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS16760
gene id: 1543721:AAY24_RS16760
uniprot id: A0A0F7K5X7
names: Similarity
messages: Belongs to the ClpX chaperone family.

1543721:AAY24 RS02620
gene id: 1543721:AAY24_RS02620
uniprot id: A0A0F7JXP9
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS11910
gene id: 1543721:AAY24_RS11910
uniprot id: A0A0F7K178
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1543721:AAY24 RS02945
gene id: 1543721:AAY24_RS02945
uniprot id: A0A0F7JSP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS10400
gene id: 1543721:AAY24_RS10400
uniprot id: A0A0F7K0L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1543721:AAY24 RS16360
gene id: 1543721:AAY24_RS16360
uniprot id: A0A0F7K468
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS10675
gene id: 1543721:AAY24_RS10675
uniprot id: A0A0F7K1A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1543721:AAY24 RS08300
gene id: 1543721:AAY24_RS08300
uniprot id: A0A0F7JYJ5
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1543721:AAY24 RS03345
gene id: 1543721:AAY24_RS03345
uniprot id: A0A0F7JVG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS12700
gene id: 1543721:AAY24_RS12700
uniprot id: A0A0F7K365
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1543721:AAY24 RS09430
gene id: 1543721:AAY24_RS09430
uniprot id: A0A0F7K0J9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS02245
gene id: 1543721:AAY24_RS02245
uniprot id: A0A0F7K2A0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1543721:AAY24 RS03655
gene id: 1543721:AAY24_RS03655
uniprot id: A0A0F7JT43
names: Similarity
messages: Belongs to the UPF0434 family.

1543721:AAY24 RS03180
gene id: 1543721:AAY24_RS03180
uniprot id: A0A0F7JVV2
names: Similarity
messages: Belongs to the HupH/HyaF family.

1543721:AAY24 RS10720
gene id: 1543721:AAY24_RS10720
uniprot id: A0A0F7K0Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1543721:AAY24 RS04930
gene id: 1543721:AAY24_RS04930
uniprot id: A0A0F7JW03
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1543721:AAY24 RS08915
gene id: 1543721:AAY24_RS08915
uniprot id: A0A0F7JXQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1543721:AAY24 RS17395
gene id: 1543721:AAY24_RS17395
uniprot id: A0A0F7K1S2
names: Similarity
messages: Belongs to the peptidase M1 family.

1543721:AAY24 RS14620
gene id: 1543721:AAY24_RS14620
uniprot id: A0A0F7JYC4
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1543721:AAY24 RS08295
gene id: 1543721:AAY24_RS08295
uniprot id: A0A0F7K074
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1543721:AAY24 RS07990
gene id: 1543721:AAY24_RS07990
uniprot id: A0A0F7JUQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1543721:AAY24 RS14515
gene id: 1543721:AAY24_RS14515
uniprot id: A0A0F7K0F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1543721:AAY24 RS11725
gene id: 1543721:AAY24_RS11725
uniprot id: A0A0F7JZY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS07590
gene id: 1543721:AAY24_RS07590
uniprot id: A0A0F7JX77
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1543721:AAY24 RS16630
gene id: 1543721:AAY24_RS16630
uniprot id: A0A0F7K1E7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1543721:AAY24 RS06035
gene id: 1543721:AAY24_RS06035
uniprot id: A0A0F7JYL6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1543721:AAY24 RS10345
gene id: 1543721:AAY24_RS10345
uniprot id: A0A0F7JZD9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1543721:AAY24 RS16300
gene id: 1543721:AAY24_RS16300
uniprot id: A0A0F7K372
names: Cofactor
messages: Binds 3 [4Fe-4S] clusters.

1543721:AAY24 RS06250
gene id: 1543721:AAY24_RS06250
uniprot id: A0A0F7JYS3
names: Similarity
messages: Belongs to the universal stress protein A family.

1543721:AAY24 RS06610
gene id: 1543721:AAY24_RS06610
uniprot id: A0A0F7JU49
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1543721:AAY24 RS14210
gene id: 1543721:AAY24_RS14210
uniprot id: A0A0F7K296
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1543721:AAY24 RS03820
gene id: 1543721:AAY24_RS03820
uniprot id: A0A0F7JVN9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1543721:AAY24 RS07955
gene id: 1543721:AAY24_RS07955
uniprot id: A0A0F7JZE5
names: Similarity
messages: Belongs to the BolA/IbaG family.

1543721:AAY24 RS03735
gene id: 1543721:AAY24_RS03735
uniprot id: A0A0F7JXV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1543721:AAY24 RS09450
gene id: 1543721:AAY24_RS09450
uniprot id: A0A0F7JVF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1543721:AAY24 RS16290
gene id: 1543721:AAY24_RS16290
uniprot id: A0A0F7K3Z5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1543721:AAY24 RS11145
gene id: 1543721:AAY24_RS11145
uniprot id: A0A0F7JWD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1543721:AAY24 RS18275
gene id: 1543721:AAY24_RS18275
uniprot id: A0A0F7K583
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS00925
gene id: 1543721:AAY24_RS00925
uniprot id: A0A0F7JX33
names: Similarity
messages: Belongs to the pirin family.

1543721:AAY24 RS09020
gene id: 1543721:AAY24_RS09020
uniprot id: A0A0F7K0G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1543721:AAY24 RS12440
gene id: 1543721:AAY24_RS12440
uniprot id: A0A0F7JZ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1543721:AAY24 RS12305
gene id: 1543721:AAY24_RS12305
uniprot id: A0A0F7JZ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1543721:AAY24 RS06585
gene id: 1543721:AAY24_RS06585
uniprot id: A0A0F7JU44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1543721:AAY24 RS03900
gene id: 1543721:AAY24_RS03900
uniprot id: A0A0F7JYC1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS13460
gene id: 1543721:AAY24_RS13460
uniprot id: A0A0F7K1Z3
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1543721:AAY24 RS02070
gene id: 1543721:AAY24_RS02070
uniprot id: A0A0F7JS81
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1543721:AAY24 RS02870
gene id: 1543721:AAY24_RS02870
uniprot id: A0A0F7JXS0
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1543721:AAY24 RS04890
gene id: 1543721:AAY24_RS04890
uniprot id: A0A0F7JTG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1543721:AAY24 RS03775
gene id: 1543721:AAY24_RS03775
uniprot id: A0A0F7JY88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1543721:AAY24 RS15465
gene id: 1543721:AAY24_RS15465
uniprot id: A0A0F7K2T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS12900
gene id: 1543721:AAY24_RS12900
uniprot id: A0A0F7K1Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1543721:AAY24 RS03850
gene id: 1543721:AAY24_RS03850
uniprot id: A0A0F7JVP2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1543721:AAY24 RS07845
gene id: 1543721:AAY24_RS07845
uniprot id: A0A0F7JUP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1543721:AAY24 RS10005
gene id: 1543721:AAY24_RS10005
uniprot id: A0A0F7JZB2
names: Similarity
messages: Belongs to the arginase family.

1543721:AAY24 RS00725
gene id: 1543721:AAY24_RS00725
uniprot id: A0A0F7JRR4
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1543721:AAY24 RS08645
gene id: 1543721:AAY24_RS08645
uniprot id: A0A0F7K5A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1543721:AAY24 RS01765
gene id: 1543721:AAY24_RS01765
uniprot id: A0A0F7JVC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1543721:AAY24 RS14185
gene id: 1543721:AAY24_RS14185
uniprot id: A0A0F7K0D0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1543721:AAY24 RS10560
gene id: 1543721:AAY24_RS10560
uniprot id: A0A0F7JZF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1543721:AAY24 RS07310
gene id: 1543721:AAY24_RS07310
uniprot id: A0A0F7JX27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1543721:AAY24 RS12695
gene id: 1543721:AAY24_RS12695
uniprot id: A0A0F7K0H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1543721:AAY24 RS13030
gene id: 1543721:AAY24_RS13030
uniprot id: A0A0F7K410
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1543721:AAY24 RS07305
gene id: 1543721:AAY24_RS07305
uniprot id: A0A0F7JUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1543721:AAY24 RS14195
gene id: 1543721:AAY24_RS14195
uniprot id: A0A0F7K312
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1543721:AAY24 RS05730
gene id: 1543721:AAY24_RS05730
uniprot id: A0A0F7JWA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1543721:AAY24 RS02025
gene id: 1543721:AAY24_RS02025
uniprot id: A0A0F7JX10
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1543721:AAY24 RS02530
gene id: 1543721:AAY24_RS02530
uniprot id: A0A0F7JUW7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1543721:AAY24 RS11905
gene id: 1543721:AAY24_RS11905
uniprot id: A0A0F7K016
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1543721:AAY24 RS08430
gene id: 1543721:AAY24_RS08430
uniprot id: A0A0F7JYM0
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS06615
gene id: 1543721:AAY24_RS06615
uniprot id: A0A0F7JWU5
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1543721:AAY24 RS05845
gene id: 1543721:AAY24_RS05845
uniprot id: A0A0F7JYI6
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1543721:AAY24 RS07900
gene id: 1543721:AAY24_RS07900
uniprot id: A0A0F7JZE1
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1543721:AAY24 RS10860
gene id: 1543721:AAY24_RS10860
uniprot id: A0A0F7JWA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1543721:AAY24 RS17315
gene id: 1543721:AAY24_RS17315
uniprot id: A0A0F7K1P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1543721:AAY24 RS07805
gene id: 1543721:AAY24_RS07805
uniprot id: A0A0F7JYE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1543721:AAY24 RS07295
gene id: 1543721:AAY24_RS07295
uniprot id: A0A0F7JY53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1543721:AAY24 RS01085
gene id: 1543721:AAY24_RS01085
uniprot id: A0A0F7JWM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1543721:AAY24 RS00775
gene id: 1543721:AAY24_RS00775
uniprot id: A0A0F7JUY6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1543721:AAY24 RS11715
gene id: 1543721:AAY24_RS11715
uniprot id: A0A0F7K1T4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1543721:AAY24 RS09895
gene id: 1543721:AAY24_RS09895
uniprot id: A0A0F7JVV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1543721:AAY24 RS08975
gene id: 1543721:AAY24_RS08975
uniprot id: A0A0F7JV58
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1543721:AAY24 RS02850
gene id: 1543721:AAY24_RS02850
uniprot id: A0A0F7JVR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1543721:AAY24 RS11985
gene id: 1543721:AAY24_RS11985
uniprot id: A0A0F7K028
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1543721:AAY24 RS15660
gene id: 1543721:AAY24_RS15660
uniprot id: A0A0F7K0Y0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1543721:AAY24 RS03765
gene id: 1543721:AAY24_RS03765
uniprot id: A0A0F7JT50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1543721:AAY24 RS16225
gene id: 1543721:AAY24_RS16225
uniprot id: A0A0F7K3Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1543721:AAY24 RS00845
gene id: 1543721:AAY24_RS00845
uniprot id: A0A0F7JU27
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1543721:AAY24 RS10165
gene id: 1543721:AAY24_RS10165
uniprot id: A0A0F7K0J4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS10020
gene id: 1543721:AAY24_RS10020
uniprot id: A0A0F7JY74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS17810
gene id: 1543721:AAY24_RS17810
uniprot id: A0A0F7K2U0
names: Similarity
messages: Belongs to the UPF0234 family.

1543721:AAY24 RS09780
gene id: 1543721:AAY24_RS09780
uniprot id: A0A0F7JY34
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1543721:AAY24 RS12835
gene id: 1543721:AAY24_RS12835
uniprot id: A0A0F7JZK4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1543721:AAY24 RS05745
gene id: 1543721:AAY24_RS05745
uniprot id: A0A0F7JYH2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1543721:AAY24 RS12850
gene id: 1543721:AAY24_RS12850
uniprot id: A0A0F7K1P3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1543721:AAY24 RS04340
gene id: 1543721:AAY24_RS04340
uniprot id: A0A0F7JWF9
names: Similarity
messages: Belongs to the asparagine synthetase family.

1543721:AAY24 RS03650
gene id: 1543721:AAY24_RS03650
uniprot id: A0A0F7JXU7
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1543721:AAY24 RS04070
gene id: 1543721:AAY24_RS04070
uniprot id: A0A0F7JXY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS11455
gene id: 1543721:AAY24_RS11455
uniprot id: A0A0F7JWJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1543721:AAY24 RS00795
gene id: 1543721:AAY24_RS00795
uniprot id: A0A0F7JX03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1543721:AAY24 RS00885
gene id: 1543721:AAY24_RS00885
uniprot id: A0A0F7JWJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1543721:AAY24 RS05085
gene id: 1543721:AAY24_RS05085
uniprot id: A0A0F7JW09
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1543721:AAY24 RS10095
gene id: 1543721:AAY24_RS10095
uniprot id: A0A0F7JZB8
names: Similarity
messages: Belongs to the PhoH family.

1543721:AAY24 RS05880
gene id: 1543721:AAY24_RS05880
uniprot id: A0A0F7JYJ0
names: Similarity
messages: Belongs to the threonine synthase family.

1543721:AAY24 RS03405
gene id: 1543721:AAY24_RS03405
uniprot id: A0A0F7JVY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1543721:AAY24 RS10480
gene id: 1543721:AAY24_RS10480
uniprot id: A0A0F7JYA5
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1543721:AAY24 RS00740
gene id: 1543721:AAY24_RS00740
uniprot id: A0A0F7JUY3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1543721:AAY24 RS10950
gene id: 1543721:AAY24_RS10950
uniprot id: A0A0F7K3W5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS12155
gene id: 1543721:AAY24_RS12155
uniprot id: A0A0F7K210
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1543721:AAY24 RS06570
gene id: 1543721:AAY24_RS06570
uniprot id: A0A0F7JZR1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1543721:AAY24 RS16520
gene id: 1543721:AAY24_RS16520
uniprot id: A0A0F7K423
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS14540
gene id: 1543721:AAY24_RS14540
uniprot id: A0A0F7K0G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1543721:AAY24 RS07490
gene id: 1543721:AAY24_RS07490
uniprot id: A0A0F7JX40
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1543721:AAY24 RS04015
gene id: 1543721:AAY24_RS04015
uniprot id: A0A0F7JXY4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1543721:AAY24 RS05690
gene id: 1543721:AAY24_RS05690
uniprot id: A0A0F7JZ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1543721:AAY24 RS09980
gene id: 1543721:AAY24_RS09980
uniprot id: A0A0F7K0E8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1543721:AAY24 RS13380
gene id: 1543721:AAY24_RS13380
uniprot id: A0A0F7JXI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1543721:AAY24 RS06370
gene id: 1543721:AAY24_RS06370
uniprot id: A0A0F7JYT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1543721:AAY24 RS00045
gene id: 1543721:AAY24_RS00045
uniprot id: A0A0F7JWP7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1543721:AAY24 RS17630
gene id: 1543721:AAY24_RS17630
uniprot id: A0A0F7JZT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS14740
gene id: 1543721:AAY24_RS14740
uniprot id: A0A0F7K0J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1543721:AAY24 RS04105
gene id: 1543721:AAY24_RS04105
uniprot id: A0A0F7JXY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

1543721:AAY24 RS09495
gene id: 1543721:AAY24_RS09495
uniprot id: A0A0F7JZ13
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1543721:AAY24 RS13090
gene id: 1543721:AAY24_RS13090
uniprot id: A0A0F7JZQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1543721:AAY24 RS05055
gene id: 1543721:AAY24_RS05055
uniprot id: A0A0F7JWT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1543721:AAY24 RS12630
gene id: 1543721:AAY24_RS12630
uniprot id: A0A0F7JZ87
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1543721:AAY24 RS02230
gene id: 1543721:AAY24_RS02230
uniprot id: A0A0F7JX47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1543721:AAY24 RS14150
gene id: 1543721:AAY24_RS14150
uniprot id: A0A0F7K167
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1543721:AAY24 RS17170
gene id: 1543721:AAY24_RS17170
uniprot id: A0A0F7K2J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1543721:AAY24 RS03465
gene id: 1543721:AAY24_RS03465
uniprot id: A0A0F7JT22
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1543721:AAY24 RS04200
gene id: 1543721:AAY24_RS04200
uniprot id: A0A0F7JYH9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1543721:AAY24 RS17360
gene id: 1543721:AAY24_RS17360
uniprot id: A0A0F7K3I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1543721:AAY24 RS04700
gene id: 1543721:AAY24_RS04700
uniprot id: A0A0F7JVZ6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1543721:AAY24 RS02715
gene id: 1543721:AAY24_RS02715
uniprot id: A0A0F7JXR1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1543721:AAY24 RS07255
gene id: 1543721:AAY24_RS07255
uniprot id: A0A0F7JZX9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1543721:AAY24 RS15280
gene id: 1543721:AAY24_RS15280
uniprot id: A0A0F7K1N4
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS13325
gene id: 1543721:AAY24_RS13325
uniprot id: A0A0F7JZU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1543721:AAY24 RS17145
gene id: 1543721:AAY24_RS17145
uniprot id: A0A0F7K3G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1543721:AAY24 RS05030
gene id: 1543721:AAY24_RS05030
uniprot id: A0A0F7JY76
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1543721:AAY24 RS06520
gene id: 1543721:AAY24_RS06520
uniprot id: A0A0F7JU35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1543721:AAY24 RS07250
gene id: 1543721:AAY24_RS07250
uniprot id: A0A0F7JX25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1543721:AAY24 RS17085
gene id: 1543721:AAY24_RS17085
uniprot id: A0A0F7K3G3
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS03980
gene id: 1543721:AAY24_RS03980
uniprot id: A0A0F7JWA5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1543721:AAY24 RS13050
gene id: 1543721:AAY24_RS13050
uniprot id: A0A0F7K1T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1543721:AAY24 RS00570
gene id: 1543721:AAY24_RS00570
uniprot id: A0A0F7JTX1
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS07510
gene id: 1543721:AAY24_RS07510
uniprot id: A0A0F7JZA9
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1543721:AAY24 RS12905
gene id: 1543721:AAY24_RS12905
uniprot id: A0A0F7JX76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1543721:AAY24 RS09470
gene id: 1543721:AAY24_RS09470
uniprot id: A0A0F7JZ10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1543721:AAY24 RS16980
gene id: 1543721:AAY24_RS16980
uniprot id: A0A0F7K3F1
names: Similarity
messages: Belongs to the HupH/HyaF family.

1543721:AAY24 RS18100
gene id: 1543721:AAY24_RS18100
uniprot id: A0A0F7K1Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1543721:AAY24 RS14850
gene id: 1543721:AAY24_RS14850
uniprot id: A0A0F7K3A5
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1543721:AAY24 RS14440
gene id: 1543721:AAY24_RS14440
uniprot id: A0A0F7K356
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1543721:AAY24 RS05875
gene id: 1543721:AAY24_RS05875
uniprot id: A0A0F7JX80
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.

1543721:AAY24 RS03385
gene id: 1543721:AAY24_RS03385
uniprot id: A0A0F7JXM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1543721:AAY24 RS13205
gene id: 1543721:AAY24_RS13205
uniprot id: A0A0F7JXC2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1543721:AAY24 RS01450
gene id: 1543721:AAY24_RS01450
uniprot id: A0A0F7JRY1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1543721:AAY24 RS11395
gene id: 1543721:AAY24_RS11395
uniprot id: A0A0F7JZT5
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS12810
gene id: 1543721:AAY24_RS12810
uniprot id: A0A0F7JZK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1543721:AAY24 RS08065
gene id: 1543721:AAY24_RS08065
uniprot id: A0A0F7JZF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1543721:AAY24 RS09415
gene id: 1543721:AAY24_RS09415
uniprot id: A0A0F7K019
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1543721:AAY24 RS07300
gene id: 1543721:AAY24_RS07300
uniprot id: A0A0F7JZ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1543721:AAY24 RS13335
gene id: 1543721:AAY24_RS13335
uniprot id: A0A0F7K2M7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1543721:AAY24 RS07410
gene id: 1543721:AAY24_RS07410
uniprot id: A0A0F7JZZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1543721:AAY24 RS15535
gene id: 1543721:AAY24_RS15535
uniprot id: A0A0F7JYX0
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

1543721:AAY24 RS18765
gene id: 1543721:AAY24_RS18765
uniprot id: A0A0F7K4Q5
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS08090
gene id: 1543721:AAY24_RS08090
uniprot id: A0A0F7JYG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1543721:AAY24 RS12650
gene id: 1543721:AAY24_RS12650
uniprot id: A0A0F7JX42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1543721:AAY24 RS00460
gene id: 1543721:AAY24_RS00460
uniprot id: A0A0F7JUW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS04675
gene id: 1543721:AAY24_RS04675
uniprot id: A0A0F7JWN1
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1543721:AAY24 RS16960
gene id: 1543721:AAY24_RS16960
uniprot id: A0A0F7JZL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1543721:AAY24 RS05600
gene id: 1543721:AAY24_RS05600
uniprot id: A0A0F7JW92
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS00385
gene id: 1543721:AAY24_RS00385
uniprot id: A0A0F7JWD5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1543721:AAY24 RS03400
gene id: 1543721:AAY24_RS03400
uniprot id: A0A0F7JY10
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS02425
gene id: 1543721:AAY24_RS02425
uniprot id: A0A0F7JUU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1543721:AAY24 RS14565
gene id: 1543721:AAY24_RS14565
uniprot id: A0A0F7K2E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1543721:AAY24 RS01925
gene id: 1543721:AAY24_RS01925
uniprot id: A0A0F7JXH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1543721:AAY24 RS05835
gene id: 1543721:AAY24_RS05835
uniprot id: A0A0F7JZ22
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1543721:AAY24 RS05215
gene id: 1543721:AAY24_RS05215
uniprot id: A0A0F7JTL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1543721:AAY24 RS04080
gene id: 1543721:AAY24_RS04080
uniprot id: A0A0F7JVR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1543721:AAY24 RS09615
gene id: 1543721:AAY24_RS09615
uniprot id: A0A0F7JZ74
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS09290
gene id: 1543721:AAY24_RS09290
uniprot id: A0A0F7K000
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1543721:AAY24 RS11825
gene id: 1543721:AAY24_RS11825
uniprot id: A0A0F7K1V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1543721:AAY24 RS09970
gene id: 1543721:AAY24_RS09970
uniprot id: A0A0F7K0Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1543721:AAY24 RS10935
gene id: 1543721:AAY24_RS10935
uniprot id: A0A0F7K1F0
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1543721:AAY24 RS09850
gene id: 1543721:AAY24_RS09850
uniprot id: A0A0F7JZA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1543721:AAY24 RS16500
gene id: 1543721:AAY24_RS16500
uniprot id: A0A0F7K2B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS16155
gene id: 1543721:AAY24_RS16155
uniprot id: A0A0F7K3Y1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1543721:AAY24 RS02130
gene id: 1543721:AAY24_RS02130
uniprot id: A0A0F7JXK3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1543721:AAY24 RS15415
gene id: 1543721:AAY24_RS15415
uniprot id: A0A0F7K0T5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1543721:AAY24 RS17055
gene id: 1543721:AAY24_RS17055
uniprot id: A0A0F7K2I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1543721:AAY24 RS00855
gene id: 1543721:AAY24_RS00855
uniprot id: A0A0F7JUY9
names: Similarity
messages: Belongs to the peptidase S8 family.

1543721:AAY24 RS04590
gene id: 1543721:AAY24_RS04590
uniprot id: A0A0F7JVY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS11650
gene id: 1543721:AAY24_RS11650
uniprot id: A0A0F7JYZ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS10465
gene id: 1543721:AAY24_RS10465
uniprot id: A0A0F7K0M6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1543721:AAY24 RS03170
gene id: 1543721:AAY24_RS03170
uniprot id: A0A0F7JVD6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1543721:AAY24 RS14635
gene id: 1543721:AAY24_RS14635
uniprot id: A0A0F7K1E3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1543721:AAY24 RS11890
gene id: 1543721:AAY24_RS11890
uniprot id: A0A0F7JWN2
names: Similarity
messages: Belongs to the peptidase U62 family.

1543721:AAY24 RS12070
gene id: 1543721:AAY24_RS12070
uniprot id: A0A0F7K1Z5
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1543721:AAY24 RS00105
gene id: 1543721:AAY24_RS00105
uniprot id: A0A0F7JTN2
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1543721:AAY24 RS16720
gene id: 1543721:AAY24_RS16720
uniprot id: A0A0F7JZJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

1543721:AAY24 RS13715
gene id: 1543721:AAY24_RS13715
uniprot id: A0A0F7K237
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1543721:AAY24 RS01400
gene id: 1543721:AAY24_RS01400
uniprot id: A0A0F7JV63
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS09380
gene id: 1543721:AAY24_RS09380
uniprot id: A0A0F7K014
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1543721:AAY24 RS01290
gene id: 1543721:AAY24_RS01290
uniprot id: A0A0F7JX65
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS14500
gene id: 1543721:AAY24_RS14500
uniprot id: A0A0F7K1B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1543721:AAY24 RS08110
gene id: 1543721:AAY24_RS08110
uniprot id: A0A0F7JXE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS11765
gene id: 1543721:AAY24_RS11765
uniprot id: A0A0F7JZ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1543721:AAY24 RS12920
gene id: 1543721:AAY24_RS12920
uniprot id: A0A0F7K0K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1543721:AAY24 RS12555
gene id: 1543721:AAY24_RS12555
uniprot id: A0A0F7K274
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1543721:AAY24 RS04725
gene id: 1543721:AAY24_RS04725
uniprot id: A0A0F7JTD8
names: Similarity
messages: Belongs to the hemerythrin family.

1543721:AAY24 RS12975
gene id: 1543721:AAY24_RS12975
uniprot id: A0A0F7JZN9
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

1543721:AAY24 RS16700
gene id: 1543721:AAY24_RS16700
uniprot id: A0A0F7K443
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1543721:AAY24 RS02210
gene id: 1543721:AAY24_RS02210
uniprot id: A0A0F7JS99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS06480
gene id: 1543721:AAY24_RS06480
uniprot id: A0A0F7JYV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1543721:AAY24 RS00200
gene id: 1543721:AAY24_RS00200
uniprot id: A0A0F7JWS7
names: Similarity
messages: Belongs to the oxoprolinase family.

1543721:AAY24 RS14380
gene id: 1543721:AAY24_RS14380
uniprot id: A0A0F7JY67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1543721:AAY24 RS07965
gene id: 1543721:AAY24_RS07965
uniprot id: A0A0F7JXD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS17135
gene id: 1543721:AAY24_RS17135
uniprot id: A0A0F7K488
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1543721:AAY24 RS09720
gene id: 1543721:AAY24_RS09720
uniprot id: A0A0F7JY26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1543721:AAY24 RS10155
gene id: 1543721:AAY24_RS10155
uniprot id: A0A0F7JVY5
names: Similarity
messages: Belongs to the leucine-binding protein family.

1543721:AAY24 RS04905
gene id: 1543721:AAY24_RS04905
uniprot id: A0A0F7JYR2
names: Similarity
messages: Belongs to the UPF0166 family.

1543721:AAY24 RS19590
gene id: 1543721:AAY24_RS19590
uniprot id: A0A0F7K2A3
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1543721:AAY24 RS13300
gene id: 1543721:AAY24_RS13300
uniprot id: A0A0F7JZT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS02780
gene id: 1543721:AAY24_RS02780
uniprot id: A0A0F7JVR2
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1543721:AAY24 RS08190
gene id: 1543721:AAY24_RS08190
uniprot id: A0A0F7JUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS12365
gene id: 1543721:AAY24_RS12365
uniprot id: A0A0F7K249
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS14820
gene id: 1543721:AAY24_RS14820
uniprot id: A0A0F7K3A1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1543721:AAY24 RS06145
gene id: 1543721:AAY24_RS06145
uniprot id: A0A0F7JYN7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS16190
gene id: 1543721:AAY24_RS16190
uniprot id: A0A0F7K3Y5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

1543721:AAY24 RS07550
gene id: 1543721:AAY24_RS07550
uniprot id: A0A0F7JUJ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1543721:AAY24 RS09680
gene id: 1543721:AAY24_RS09680
uniprot id: A0A0F7K0A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1543721:AAY24 RS05815
gene id: 1543721:AAY24_RS05815
uniprot id: A0A0F7JX68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1543721:AAY24 RS01485
gene id: 1543721:AAY24_RS01485
uniprot id: A0A0F7K338
names: Similarity
messages: Belongs to the SfsA family.

1543721:AAY24 RS09660
gene id: 1543721:AAY24_RS09660
uniprot id: A0A0F7JY05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1543721:AAY24 RS02105
gene id: 1543721:AAY24_RS02105
uniprot id: A0A0F7JXJ8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1543721:AAY24 RS10060
gene id: 1543721:AAY24_RS10060
uniprot id: A0A0F7K0Z4
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1543721:AAY24 RS08945
gene id: 1543721:AAY24_RS08945
uniprot id: A0A0F7K0G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1543721:AAY24 RS02500
gene id: 1543721:AAY24_RS02500
uniprot id: A0A0F7JUW0
names: Similarity
messages: Belongs to the universal stress protein A family.

1543721:AAY24 RS09530
gene id: 1543721:AAY24_RS09530
uniprot id: A0A0F7K037
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1543721:AAY24 RS05500
gene id: 1543721:AAY24_RS05500
uniprot id: A0A0F7JYE6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1543721:AAY24 RS16400
gene id: 1543721:AAY24_RS16400
uniprot id: A0A0F7K1A8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1543721:AAY24 RS04770
gene id: 1543721:AAY24_RS04770
uniprot id: A0A0F7JWN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1543721:AAY24 RS14235
gene id: 1543721:AAY24_RS14235
uniprot id: A0A0F7K188
names: Similarity
messages: Belongs to the CutA family.

1543721:AAY24 RS07360
gene id: 1543721:AAY24_RS07360
uniprot id: A0A0F7JY66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1543721:AAY24 RS00815
gene id: 1543721:AAY24_RS00815
uniprot id: A0A0F7JWJ1
names: Similarity
messages: Belongs to the peptidase S16 family.

1543721:AAY24 RS08350
gene id: 1543721:AAY24_RS08350
uniprot id: A0A0F7JYK6
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1543721:AAY24 RS15980
gene id: 1543721:AAY24_RS15980
uniprot id: A0A0F7K3V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1543721:AAY24 RS01365
gene id: 1543721:AAY24_RS01365
uniprot id: A0A0F7JUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1543721:AAY24 RS10495
gene id: 1543721:AAY24_RS10495
uniprot id: A0A0F7K0M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1543721:AAY24 RS03250
gene id: 1543721:AAY24_RS03250
uniprot id: A0A0F7JSV6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1543721:AAY24 RS06265
gene id: 1543721:AAY24_RS06265
uniprot id: A0A0F7JWF8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1543721:AAY24 RS08270
gene id: 1543721:AAY24_RS08270
uniprot id: A0A0F7JYJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1543721:AAY24 RS05460
gene id: 1543721:AAY24_RS05460
uniprot id: A0A0F7JWY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1543721:AAY24 RS05240
gene id: 1543721:AAY24_RS05240
uniprot id: A0A0F7JWV6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS08260
gene id: 1543721:AAY24_RS08260
uniprot id: A0A0F7JXF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1543721:AAY24 RS16645
gene id: 1543721:AAY24_RS16645
uniprot id: A0A0F7K3B1
names: Similarity
messages: Belongs to the NifX/NifY family.

1543721:AAY24 RS05120
gene id: 1543721:AAY24_RS05120
uniprot id: A0A0F7JWU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1543721:AAY24 RS11130
gene id: 1543721:AAY24_RS11130
uniprot id: A0A0F7K5H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1543721:AAY24 RS03230
gene id: 1543721:AAY24_RS03230
uniprot id: A0A0F7JXX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1543721:AAY24 RS08345
gene id: 1543721:AAY24_RS08345
uniprot id: A0A0F7K081
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1543721:AAY24 RS06475
gene id: 1543721:AAY24_RS06475
uniprot id: A0A0F7JXM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1543721:AAY24 RS00380
gene id: 1543721:AAY24_RS00380
uniprot id: A0A0F7JUT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1543721:AAY24 RS12910
gene id: 1543721:AAY24_RS12910
uniprot id: A0A0F7JZN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1543721:AAY24 RS13405
gene id: 1543721:AAY24_RS13405
uniprot id: A0A0F7JXJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS07840
gene id: 1543721:AAY24_RS07840
uniprot id: A0A0F7JZD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1543721:AAY24 RS14895
gene id: 1543721:AAY24_RS14895
uniprot id: A0A0F7K3A0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1543721:AAY24 RS10690
gene id: 1543721:AAY24_RS10690
uniprot id: A0A0F7JW79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1543721:AAY24 RS06535
gene id: 1543721:AAY24_RS06535
uniprot id: A0A0F7JZQ5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1543721:AAY24 RS09345
gene id: 1543721:AAY24_RS09345
uniprot id: A0A0F7K010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1543721:AAY24 RS08220
gene id: 1543721:AAY24_RS08220
uniprot id: A0A0F7JUU3
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS04235
gene id: 1543721:AAY24_RS04235
uniprot id: A0A0F7K4X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS17330
gene id: 1543721:AAY24_RS17330
uniprot id: A0A0F7K3I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1543721:AAY24 RS07950
gene id: 1543721:AAY24_RS07950
uniprot id: A0A0F7JYF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1543721:AAY24 RS13065
gene id: 1543721:AAY24_RS13065
uniprot id: A0A0F7K2J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1543721:AAY24 RS01045
gene id: 1543721:AAY24_RS01045
uniprot id: A0A0F7JU61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS18115
gene id: 1543721:AAY24_RS18115
uniprot id: A0A0F7K3X2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

1543721:AAY24 RS15690
gene id: 1543721:AAY24_RS15690
uniprot id: A0A0F7K3Q1
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS04950
gene id: 1543721:AAY24_RS04950
uniprot id: A0A0F7JTI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1543721:AAY24 RS02985
gene id: 1543721:AAY24_RS02985
uniprot id: A0A0F7JVT7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1543721:AAY24 RS10460
gene id: 1543721:AAY24_RS10460
uniprot id: A0A0F7JZE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1543721:AAY24 RS01355
gene id: 1543721:AAY24_RS01355
uniprot id: A0A0F7JWR7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1543721:AAY24 RS10015
gene id: 1543721:AAY24_RS10015
uniprot id: A0A0F7JVX0
names: Similarity
messages: Belongs to the PrpD family.

1543721:AAY24 RS16970
gene id: 1543721:AAY24_RS16970
uniprot id: A0A0F7K469
names: Similarity
messages: Belongs to the peptidase A31 family.

1543721:AAY24 RS05410
gene id: 1543721:AAY24_RS05410
uniprot id: A0A0F7JYE0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1543721:AAY24 RS15875
gene id: 1543721:AAY24_RS15875
uniprot id: A0A0F7K319
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1543721:AAY24 RS02050
gene id: 1543721:AAY24_RS02050
uniprot id: A0A0F7JXI7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1543721:AAY24 RS08135
gene id: 1543721:AAY24_RS08135
uniprot id: A0A0F7JUT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1543721:AAY24 RS00285
gene id: 1543721:AAY24_RS00285
uniprot id: A0A0F7JRG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

1543721:AAY24 RS15430
gene id: 1543721:AAY24_RS15430
uniprot id: A0A0F7K4Z8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1543721:AAY24 RS10125
gene id: 1543721:AAY24_RS10125
uniprot id: A0A0F7K0G7
names: Similarity
messages: Belongs to the peptidase M16 family.

1543721:AAY24 RS17335
gene id: 1543721:AAY24_RS17335
uniprot id: A0A0F7JZP4
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS10140
gene id: 1543721:AAY24_RS10140
uniprot id: A0A0F7K124
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1543721:AAY24 RS15295
gene id: 1543721:AAY24_RS15295
uniprot id: A0A0F7K0Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1543721:AAY24 RS14105
gene id: 1543721:AAY24_RS14105
uniprot id: A0A0F7JY25
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1543721:AAY24 RS09760
gene id: 1543721:AAY24_RS09760
uniprot id: A0A0F7JZ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1543721:AAY24 RS07630
gene id: 1543721:AAY24_RS07630
uniprot id: A0A0F7JX82
names: Similarity
messages: Belongs to the thioredoxin family.

1543721:AAY24 RS17130
gene id: 1543721:AAY24_RS17130
uniprot id: A0A0F7K1L6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1543721:AAY24 RS07970
gene id: 1543721:AAY24_RS07970
uniprot id: A0A0F7K058
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1543721:AAY24 RS05255
gene id: 1543721:AAY24_RS05255
uniprot id: A0A0F7JTL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1543721:AAY24 RS13095
gene id: 1543721:AAY24_RS13095
uniprot id: A0A0F7K2J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS17885
gene id: 1543721:AAY24_RS17885
uniprot id: A0A0F7K1W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1543721:AAY24 RS00390
gene id: 1543721:AAY24_RS00390
uniprot id: A0A0F7JRI2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1543721:AAY24 RS02540
gene id: 1543721:AAY24_RS02540
uniprot id: A0A0F7JVN4
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1543721:AAY24 RS16950
gene id: 1543721:AAY24_RS16950
uniprot id: A0A0F7K2H4
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1543721:AAY24 RS09265
gene id: 1543721:AAY24_RS09265
uniprot id: A0A0F7JZZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1543721:AAY24 RS13100
gene id: 1543721:AAY24_RS13100
uniprot id: A0A0F7K0N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS10230
gene id: 1543721:AAY24_RS10230
uniprot id: A0A0F7K136
names: Similarity
messages: Belongs to the leucine-binding protein family.

1543721:AAY24 RS01490
gene id: 1543721:AAY24_RS01490
uniprot id: A0A0F7JXA1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1543721:AAY24 RS13855
gene id: 1543721:AAY24_RS13855
uniprot id: A0A0F7K065
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS07290
gene id: 1543721:AAY24_RS07290
uniprot id: A0A0F7K0R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1543721:AAY24 RS05205
gene id: 1543721:AAY24_RS05205
uniprot id: A0A0F7JWV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1543721:AAY24 RS08690
gene id: 1543721:AAY24_RS08690
uniprot id: A0A0F7JV20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1543721:AAY24 RS03990
gene id: 1543721:AAY24_RS03990
uniprot id: A0A0F7JXY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1543721:AAY24 RS01560
gene id: 1543721:AAY24_RS01560
uniprot id: A0A0F7JWS4
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1543721:AAY24 RS01600
gene id: 1543721:AAY24_RS01600
uniprot id: A0A0F7JRZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1543721:AAY24 RS03620
gene id: 1543721:AAY24_RS03620
uniprot id: A0A0F7JW43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1543721:AAY24 RS16725
gene id: 1543721:AAY24_RS16725
uniprot id: A0A0F7K1G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

1543721:AAY24 RS04050
gene id: 1543721:AAY24_RS04050
uniprot id: A0A0F7JVR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1543721:AAY24 RS02915
gene id: 1543721:AAY24_RS02915
uniprot id: A0A0F7JXE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS08100
gene id: 1543721:AAY24_RS08100
uniprot id: A0A0F7JUR1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS05415
gene id: 1543721:AAY24_RS05415
uniprot id: A0A0F7JTN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1543721:AAY24 RS02790
gene id: 1543721:AAY24_RS02790
uniprot id: A0A0F7JSM5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1543721:AAY24 RS15410
gene id: 1543721:AAY24_RS15410
uniprot id: A0A0F7JYU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1543721:AAY24 RS04825
gene id: 1543721:AAY24_RS04825
uniprot id: A0A0F7JWP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS08575
gene id: 1543721:AAY24_RS08575
uniprot id: A0A0F7JZJ9
names: Similarity
messages: Belongs to the YfgM family.

1543721:AAY24 RS01505
gene id: 1543721:AAY24_RS01505
uniprot id: A0A0F7JRY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1543721:AAY24 RS08695
gene id: 1543721:AAY24_RS08695
uniprot id: A0A0F7JXK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1543721:AAY24 RS04485
gene id: 1543721:AAY24_RS04485
uniprot id: A0A0F7JWK6
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1543721:AAY24 RS06065
gene id: 1543721:AAY24_RS06065
uniprot id: A0A0F7JYM1
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS11080
gene id: 1543721:AAY24_RS11080
uniprot id: A0A0F7K0W4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1543721:AAY24 RS18280
gene id: 1543721:AAY24_RS18280
uniprot id: A0A0F7K1H5
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1543721:AAY24 RS07325
gene id: 1543721:AAY24_RS07325
uniprot id: A0A0F7JZ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1543721:AAY24 RS04940
gene id: 1543721:AAY24_RS04940
uniprot id: A0A0F7JWQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1543721:AAY24 RS00720
gene id: 1543721:AAY24_RS00720
uniprot id: A0A0F7JWI8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1543721:AAY24 RS10755
gene id: 1543721:AAY24_RS10755
uniprot id: A0A0F7K0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Periplasm

1543721:AAY24 RS08085
gene id: 1543721:AAY24_RS08085
uniprot id: A0A0F7K067
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1543721:AAY24 RS03125
gene id: 1543721:AAY24_RS03125
uniprot id: A0A0F7JVU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS12540
gene id: 1543721:AAY24_RS12540
uniprot id: A0A0F7JWX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1543721:AAY24 RS11250
gene id: 1543721:AAY24_RS11250
uniprot id: A0A0F7K1K0
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1543721:AAY24 RS02560
gene id: 1543721:AAY24_RS02560
uniprot id: A0A0F7JXP3
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1543721:AAY24 RS05975
gene id: 1543721:AAY24_RS05975
uniprot id: A0A0F7JTU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS01855
gene id: 1543721:AAY24_RS01855
uniprot id: A0A0F7JWY9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1543721:AAY24 RS14855
gene id: 1543721:AAY24_RS14855
uniprot id: A0A0F7K1G7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1543721:AAY24 RS07855
gene id: 1543721:AAY24_RS07855
uniprot id: A0A0F7K041
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1543721:AAY24 RS01310
gene id: 1543721:AAY24_RS01310
uniprot id: A0A0F7JU94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1543721:AAY24 RS12715
gene id: 1543721:AAY24_RS12715
uniprot id: A0A0F7JX52
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1543721:AAY24 RS05365
gene id: 1543721:AAY24_RS05365
uniprot id: A0A0F7JW59
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1543721:AAY24 RS07785
gene id: 1543721:AAY24_RS07785
uniprot id: A0A0F7JZD2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1543721:AAY24 RS05170
gene id: 1543721:AAY24_RS05170
uniprot id: A0A0F7JYW2
names: Similarity
messages: Belongs to the elongation factor P family.

1543721:AAY24 RS14460
gene id: 1543721:AAY24_RS14460
uniprot id: A0A0F7K0F2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1543721:AAY24 RS10485
gene id: 1543721:AAY24_RS10485
uniprot id: A0A0F7K176
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1543721:AAY24 RS14385
gene id: 1543721:AAY24_RS14385
uniprot id: A0A0F7K169
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1543721:AAY24 RS13705
gene id: 1543721:AAY24_RS13705
uniprot id: A0A0F7K2T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS01010
gene id: 1543721:AAY24_RS01010
uniprot id: A0A0F7JRT3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1543721:AAY24 RS03490
gene id: 1543721:AAY24_RS03490
uniprot id: A0A0F7JW36
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1543721:AAY24 RS05015
gene id: 1543721:AAY24_RS05015
uniprot id: A0A0F7JW06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1543721:AAY24 RS17365
gene id: 1543721:AAY24_RS17365
uniprot id: A0A0F7JZP8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1543721:AAY24 RS08560
gene id: 1543721:AAY24_RS08560
uniprot id: A0A0F7K097
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1543721:AAY24 RS02745
gene id: 1543721:AAY24_RS02745
uniprot id: A0A0F7JVQ9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS16295
gene id: 1543721:AAY24_RS16295
uniprot id: A0A0F7K291
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS02910
gene id: 1543721:AAY24_RS02910
uniprot id: A0A0F7K2B8
names: Subcellular Location Annotation
messages: Cytoplasm

1543721:AAY24 RS04980
gene id: 1543721:AAY24_RS04980
uniprot id: A0A0F7K500
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1543721:AAY24 RS01900
gene id: 1543721:AAY24_RS01900
uniprot id: A0A0F7JXG9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS02925
gene id: 1543721:AAY24_RS02925
uniprot id: A0A0F7JV87
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1543721:AAY24 RS08565
gene id: 1543721:AAY24_RS08565
uniprot id: A0A0F7JYN9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1543721:AAY24 RS03380
gene id: 1543721:AAY24_RS03380
uniprot id: A0A0F7JVY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1543721:AAY24 RS16810
gene id: 1543721:AAY24_RS16810
uniprot id: A0A0F7K2F6
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS09905
gene id: 1543721:AAY24_RS09905
uniprot id: A0A0F7K0X3
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1543721:AAY24 RS06750
gene id: 1543721:AAY24_RS06750
uniprot id: A0A0F7JZT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1543721:AAY24 RS03255
gene id: 1543721:AAY24_RS03255
uniprot id: A0A0F7JVF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1543721:AAY24 RS12580
gene id: 1543721:AAY24_RS12580
uniprot id: A0A0F7JZ79
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS02525
gene id: 1543721:AAY24_RS02525
uniprot id: A0A0F7JSD6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1543721:AAY24 RS04605
gene id: 1543721:AAY24_RS04605
uniprot id: A0A0F7JWM3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS12775
gene id: 1543721:AAY24_RS12775
uniprot id: A0A0F7JZJ8
names: Similarity
messages: Belongs to the peptidase S41A family.

1543721:AAY24 RS14270
gene id: 1543721:AAY24_RS14270
uniprot id: A0A0F7K190
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1543721:AAY24 RS09295
gene id: 1543721:AAY24_RS09295
uniprot id: A0A0F7JVC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1543721:AAY24 RS10780
gene id: 1543721:AAY24_RS10780
uniprot id: A0A0F7K1C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1543721:AAY24 RS06075
gene id: 1543721:AAY24_RS06075
uniprot id: A0A0F7JWE1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1543721:AAY24 RS11470
gene id: 1543721:AAY24_RS11470
uniprot id: A0A0F7K1N5
names: Similarity
messages: Belongs to the thioredoxin family.

1543721:AAY24 RS10210
gene id: 1543721:AAY24_RS10210
uniprot id: A0A0F7K0I2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1543721:AAY24 RS10515
gene id: 1543721:AAY24_RS10515
uniprot id: A0A0F7JZF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1543721:AAY24 RS14430
gene id: 1543721:AAY24_RS14430
uniprot id: A0A0F7JY73
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1543721:AAY24 RS11280
gene id: 1543721:AAY24_RS11280
uniprot id: A0A0F7K1K5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1543721:AAY24 RS13980
gene id: 1543721:AAY24_RS13980
uniprot id: A0A0F7K129
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1543721:AAY24 RS03930
gene id: 1543721:AAY24_RS03930
uniprot id: A0A0F7JYC5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1543721:AAY24 RS02305
gene id: 1543721:AAY24_RS02305
uniprot id: A0A0F7JSA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1543721:AAY24 RS02615
gene id: 1543721:AAY24_RS02615
uniprot id: A0A0F7JV34
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1543721:AAY24 RS10900
gene id: 1543721:AAY24_RS10900
uniprot id: A0A0F7K1E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane

1543721:AAY24 RS03800
gene id: 1543721:AAY24_RS03800
uniprot id: A0A0F7JY93
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1543721:AAY24 RS17120
gene id: 1543721:AAY24_RS17120
uniprot id: A0A0F7K3G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1543721:AAY24 RS11900
gene id: 1543721:AAY24_RS11900
uniprot id: A0A0F7K1W8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1543721:AAY24 RS05405
gene id: 1543721:AAY24_RS05405
uniprot id: A0A0F7JWX3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1543721:AAY24 RS08175
gene id: 1543721:AAY24_RS08175
uniprot id: A0A0F7JYH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1543721:AAY24 RS15090
gene id: 1543721:AAY24_RS15090
uniprot id: A0A0F7K1K3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1543721:AAY24 RS06125
gene id: 1543721:AAY24_RS06125
uniprot id: A0A0F7JTX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1543721:AAY24 RS00365
gene id: 1543721:AAY24_RS00365
uniprot id: A0A0F7JTS3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1543721:AAY24 RS19080
gene id: 1543721:AAY24_RS19080
uniprot id: A0A0F7JUF8
names: Similarity
messages: Belongs to the HisA/HisF family.

1543721:AAY24 RS15650
gene id: 1543721:AAY24_RS15650
uniprot id: A0A0F7K2W9
names: Function
names: Similarity
messages: Belongs to the RuBisCO large chain family. Type II subfamily.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.

1543721:AAY24 RS14470
gene id: 1543721:AAY24_RS14470
uniprot id: A0A0F7K1B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1543721:AAY24 RS09865
gene id: 1543721:AAY24_RS09865
uniprot id: A0A0F7JVV0
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1543721:AAY24 RS01550
gene id: 1543721:AAY24_RS01550
uniprot id: A0A0F7JV89
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1543721:AAY24 RS14645
gene id: 1543721:AAY24_RS14645
uniprot id: A0A0F7JYC9
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1543721:AAY24 RS03855
gene id: 1543721:AAY24_RS03855
uniprot id: A0A0F7JYB6
names: Similarity
messages: Belongs to the nitroreductase family.

1543721:AAY24 RS17070
gene id: 1543721:AAY24_RS17070
uniprot id: A0A0F7K1K8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1543721:AAY24 RS04655
gene id: 1543721:AAY24_RS04655
uniprot id: A0A0F7JY19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS11860
gene id: 1543721:AAY24_RS11860
uniprot id: A0A0F7K170
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1543721:AAY24 RS00685
gene id: 1543721:AAY24_RS00685
uniprot id: A0A0F7JUY0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1543721:AAY24 RS15105
gene id: 1543721:AAY24_RS15105
uniprot id: A0A0F7K3A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1543721:AAY24 RS00550
gene id: 1543721:AAY24_RS00550
uniprot id: A0A0F7JWX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1543721:AAY24 RS10685
gene id: 1543721:AAY24_RS10685
uniprot id: A0A0F7K0P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS00645
gene id: 1543721:AAY24_RS00645
uniprot id: A0A0F7JWY6
names: Similarity
messages: Belongs to the MotB family.

1543721:AAY24 RS14320
gene id: 1543721:AAY24_RS14320
uniprot id: A0A0F7K0D4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1543721:AAY24 RS16495
gene id: 1543721:AAY24_RS16495
uniprot id: A0A0F7K418
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1543721:AAY24 RS04560
gene id: 1543721:AAY24_RS04560
uniprot id: A0A0F7JTC3
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1543721:AAY24 RS15310
gene id: 1543721:AAY24_RS15310
uniprot id: A0A0F7K2R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1543721:AAY24 RS13960
gene id: 1543721:AAY24_RS13960
uniprot id: A0A0F7K262
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1543721:AAY24 RS14900
gene id: 1543721:AAY24_RS14900
uniprot id: A0A0F7K1H2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1543721:AAY24 RS08905
gene id: 1543721:AAY24_RS08905
uniprot id: A0A0F7JZS0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1543721:AAY24 RS04970
gene id: 1543721:AAY24_RS04970
uniprot id: A0A0F7JY65
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1543721:AAY24 RS09215
gene id: 1543721:AAY24_RS09215
uniprot id: A0A0F7JVA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1543721:AAY24 RS01915
gene id: 1543721:AAY24_RS01915
uniprot id: A0A0F7JS66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1543721:AAY24 RS12785
gene id: 1543721:AAY24_RS12785
uniprot id: A0A0F7K2F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1543721:AAY24 RS14550
gene id: 1543721:AAY24_RS14550
uniprot id: A0A0F7K374
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1543721:AAY24 RS12340
gene id: 1543721:AAY24_RS12340
uniprot id: A0A0F7K079
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1543721:AAY24 RS14350
gene id: 1543721:AAY24_RS14350
uniprot id: A0A0F7K346
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1543721:AAY24 RS09455
gene id: 1543721:AAY24_RS09455
uniprot id: A0A0F7JXW3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS17755
gene id: 1543721:AAY24_RS17755
uniprot id: A0A0F7K4H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1543721:AAY24 RS04215
gene id: 1543721:AAY24_RS04215
uniprot id: A0A0F7JTA1
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1543721:AAY24 RS09540
gene id: 1543721:AAY24_RS09540
uniprot id: A0A0F7JXX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1543721:AAY24 RS12215
gene id: 1543721:AAY24_RS12215
uniprot id: A0A0F7JZ40
names: Similarity
messages: Belongs to the methylglyoxal synthase family.

1543721:AAY24 RS17950
gene id: 1543721:AAY24_RS17950
uniprot id: A0A0F7K3U4
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS02355
gene id: 1543721:AAY24_RS02355
uniprot id: A0A0F7JVL0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1543721:AAY24 RS03010
gene id: 1543721:AAY24_RS03010
uniprot id: A0A0F7JXU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS13110
gene id: 1543721:AAY24_RS13110
uniprot id: A0A0F7JXA8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1543721:AAY24 RS07935
gene id: 1543721:AAY24_RS07935
uniprot id: A0A0F7JUP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1543721:AAY24 RS14140
gene id: 1543721:AAY24_RS14140
uniprot id: A0A0F7K0C4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS02955
gene id: 1543721:AAY24_RS02955
uniprot id: A0A0F7JXT3
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS11445
gene id: 1543721:AAY24_RS11445
uniprot id: A0A0F7JZU4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1543721:AAY24 RS10250
gene id: 1543721:AAY24_RS10250
uniprot id: A0A0F7JY98
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1543721:AAY24 RS11935
gene id: 1543721:AAY24_RS11935
uniprot id: A0A0F7K181
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

1543721:AAY24 RS10555
gene id: 1543721:AAY24_RS10555
uniprot id: A0A0F7K182
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1543721:AAY24 RS06835
gene id: 1543721:AAY24_RS06835
uniprot id: A0A0F7JXV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS13075
gene id: 1543721:AAY24_RS13075
uniprot id: A0A0F7K1T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1543721:AAY24 RS08235
gene id: 1543721:AAY24_RS08235
uniprot id: A0A0F7K072
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1543721:AAY24 RS14520
gene id: 1543721:AAY24_RS14520
uniprot id: A0A0F7K370
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1543721:AAY24 RS11370
gene id: 1543721:AAY24_RS11370
uniprot id: A0A0F7JZS9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1543721:AAY24 RS02100
gene id: 1543721:AAY24_RS02100
uniprot id: A0A0F7JUQ5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1543721:AAY24 RS04125
gene id: 1543721:AAY24_RS04125
uniprot id: A0A0F7JWE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1543721:AAY24 RS10145
gene id: 1543721:AAY24_RS10145
uniprot id: A0A0F7JZC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1543721:AAY24 RS16745
gene id: 1543721:AAY24_RS16745
uniprot id: A0A0F7K3C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

1543721:AAY24 RS04585
gene id: 1543721:AAY24_RS04585
uniprot id: A0A0F7JTC6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1543721:AAY24 RS13055
gene id: 1543721:AAY24_RS13055
uniprot id: A0A0F7JXA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1543721:AAY24 RS09575
gene id: 1543721:AAY24_RS09575
uniprot id: A0A0F7JXZ3
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS07580
gene id: 1543721:AAY24_RS07580
uniprot id: A0A0F7JZB3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1543721:AAY24 RS04760
gene id: 1543721:AAY24_RS04760
uniprot id: A0A0F7JVZ8
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1543721:AAY24 RS07485
gene id: 1543721:AAY24_RS07485
uniprot id: A0A0F7K3N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1543721:AAY24 RS08010
gene id: 1543721:AAY24_RS08010
uniprot id: A0A0F7JYF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1543721:AAY24 RS13315
gene id: 1543721:AAY24_RS13315
uniprot id: A0A0F7K1X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

1543721:AAY24 RS03645
gene id: 1543721:AAY24_RS03645
uniprot id: A0A0F7JW44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1543721:AAY24 RS03200
gene id: 1543721:AAY24_RS03200
uniprot id: A0A0F7JXX0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1543721:AAY24 RS15780
gene id: 1543721:AAY24_RS15780
uniprot id: A0A0F7K152
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1543721:AAY24 RS06915
gene id: 1543721:AAY24_RS06915
uniprot id: A0A0F7JZW0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1543721:AAY24 RS13710
gene id: 1543721:AAY24_RS13710
uniprot id: A0A0F7K0X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS01950
gene id: 1543721:AAY24_RS01950
uniprot id: A0A0F7JUP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1543721:AAY24 RS13665
gene id: 1543721:AAY24_RS13665
uniprot id: A0A0F7JXN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS16130
gene id: 1543721:AAY24_RS16130
uniprot id: A0A0F7K3X6
names: Subcellular Location Annotation
messages: Cytoplasm

1543721:AAY24 RS13310
gene id: 1543721:AAY24_RS13310
uniprot id: A0A0F7K0S0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1543721:AAY24 RS10850
gene id: 1543721:AAY24_RS10850
uniprot id: A0A0F7JZL5
names: Subcellular Location Annotation
messages: Cytoplasm

1543721:AAY24 RS06060
gene id: 1543721:AAY24_RS06060
uniprot id: A0A0F7JXB2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS06770
gene id: 1543721:AAY24_RS06770
uniprot id: A0A0F7JWX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1543721:AAY24 RS09790
gene id: 1543721:AAY24_RS09790
uniprot id: A0A0F7K0Y5
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1543721:AAY24 RS14480
gene id: 1543721:AAY24_RS14480
uniprot id: A0A0F7JY84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1543721:AAY24 RS03390
gene id: 1543721:AAY24_RS03390
uniprot id: A0A0F7JSX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1543721:AAY24 RS12235
gene id: 1543721:AAY24_RS12235
uniprot id: A0A0F7JWT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1543721:AAY24 RS08445
gene id: 1543721:AAY24_RS08445
uniprot id: A0A0F7JUW3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

1543721:AAY24 RS11050
gene id: 1543721:AAY24_RS11050
uniprot id: A0A0F7K0V9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS03905
gene id: 1543721:AAY24_RS03905
uniprot id: A0A0F7JW98
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1543721:AAY24 RS18145
gene id: 1543721:AAY24_RS18145
uniprot id: A0A0F7K561
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26C family.
messages: Periplasm

1543721:AAY24 RS07960
gene id: 1543721:AAY24_RS07960
uniprot id: A0A0F7JUQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1543721:AAY24 RS13735
gene id: 1543721:AAY24_RS13735
uniprot id: A0A0F7K0X8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1543721:AAY24 RS10440
gene id: 1543721:AAY24_RS10440
uniprot id: A0A0F7JYA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1543721:AAY24 RS09845
gene id: 1543721:AAY24_RS09845
uniprot id: A0A0F7K0W1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1543721:AAY24 RS09350
gene id: 1543721:AAY24_RS09350
uniprot id: A0A0F7JVD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1543721:AAY24 RS09600
gene id: 1543721:AAY24_RS09600
uniprot id: A0A0F7JVK8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1543721:AAY24 RS10835
gene id: 1543721:AAY24_RS10835
uniprot id: A0A0F7JWA7
names: Cofactor
messages: Can also use Mn(2+) ion.

1543721:AAY24 RS02995
gene id: 1543721:AAY24_RS02995
uniprot id: A0A0F7JSQ6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1543721:AAY24 RS07695
gene id: 1543721:AAY24_RS07695
uniprot id: A0A0F7K3N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1543721:AAY24 RS02255
gene id: 1543721:AAY24_RS02255
uniprot id: A0A0F7K4T5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1543721:AAY24 RS13005
gene id: 1543721:AAY24_RS13005
uniprot id: A0A0F7K2I6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1543721:AAY24 RS11790
gene id: 1543721:AAY24_RS11790
uniprot id: A0A0F7JWL7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1543721:AAY24 RS08285
gene id: 1543721:AAY24_RS08285
uniprot id: A0A0F7JUU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1543721:AAY24 RS03410
gene id: 1543721:AAY24_RS03410
uniprot id: A0A0F7JXN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1543721:AAY24 RS04160
gene id: 1543721:AAY24_RS04160
uniprot id: A0A0F7JT98
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1543721:AAY24 RS09435
gene id: 1543721:AAY24_RS09435
uniprot id: A0A0F7JZ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1543721:AAY24 RS08630
gene id: 1543721:AAY24_RS08630
uniprot id: A0A0F7JV11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1543721:AAY24 RS14580
gene id: 1543721:AAY24_RS14580
uniprot id: A0A0F7K378
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1543721:AAY24 RS13295
gene id: 1543721:AAY24_RS13295
uniprot id: A0A0F7JXF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS08730
gene id: 1543721:AAY24_RS08730
uniprot id: A0A0F7K4M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS09460
gene id: 1543721:AAY24_RS09460
uniprot id: A0A0F7K0K4
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1543721:AAY24 RS02535
gene id: 1543721:AAY24_RS02535
uniprot id: A0A0F7JXP1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1543721:AAY24 RS08040
gene id: 1543721:AAY24_RS08040
uniprot id: A0A0F7JXD8
names: Similarity
messages: Belongs to the ArsC family.

1543721:AAY24 RS13120
gene id: 1543721:AAY24_RS13120
uniprot id: A0A0F7K2J8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS15330
gene id: 1543721:AAY24_RS15330
uniprot id: A0A0F7K1Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1543721:AAY24 RS16975
gene id: 1543721:AAY24_RS16975
uniprot id: A0A0F7K2H8
names: Similarity
messages: Belongs to the HupG/HyaE family.

1543721:AAY24 RS16575
gene id: 1543721:AAY24_RS16575
uniprot id: A0A0F7K431
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

1543721:AAY24 RS01110
gene id: 1543721:AAY24_RS01110
uniprot id: A0A0F7JU70
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1543721:AAY24 RS13785
gene id: 1543721:AAY24_RS13785
uniprot id: A0A0F7K245
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1543721:AAY24 RS02785
gene id: 1543721:AAY24_RS02785
uniprot id: A0A0F7JXJ8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1543721:AAY24 RS11795
gene id: 1543721:AAY24_RS11795
uniprot id: A0A0F7JZ11
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS05740
gene id: 1543721:AAY24_RS05740
uniprot id: A0A0F7JX34
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1543721:AAY24 RS07680
gene id: 1543721:AAY24_RS07680
uniprot id: A0A0F7JX92
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1543721:AAY24 RS11780
gene id: 1543721:AAY24_RS11780
uniprot id: A0A0F7K145
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1543721:AAY24 RS16515
gene id: 1543721:AAY24_RS16515
uniprot id: A0A0F7K1C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS09260
gene id: 1543721:AAY24_RS09260
uniprot id: A0A0F7JYW3
names: Similarity
messages: Belongs to the peptidase A31 family.

1543721:AAY24 RS14445
gene id: 1543721:AAY24_RS14445
uniprot id: A0A0F7K1B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1543721:AAY24 RS08115
gene id: 1543721:AAY24_RS08115
uniprot id: A0A0F7K068
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS04730
gene id: 1543721:AAY24_RS04730
uniprot id: A0A0F7JVZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS09245
gene id: 1543721:AAY24_RS09245
uniprot id: A0A0F7JVB5
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.

1543721:AAY24 RS10220
gene id: 1543721:AAY24_RS10220
uniprot id: A0A0F7K4Q7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1543721:AAY24 RS06030
gene id: 1543721:AAY24_RS06030
uniprot id: A0A0F7K4G4
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1543721:AAY24 RS15760
gene id: 1543721:AAY24_RS15760
uniprot id: A0A0F7K3T4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1543721:AAY24 RS17560
gene id: 1543721:AAY24_RS17560
uniprot id: A0A0F7JZS6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1543721:AAY24 RS03215
gene id: 1543721:AAY24_RS03215
uniprot id: A0A0F7JXJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1543721:AAY24 RS08230
gene id: 1543721:AAY24_RS08230
uniprot id: A0A0F7JXF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1543721:AAY24 RS00410
gene id: 1543721:AAY24_RS00410
uniprot id: A0A0F7JWE3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS15695
gene id: 1543721:AAY24_RS15695
uniprot id: A0A0F7K1X5
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS15710
gene id: 1543721:AAY24_RS15710
uniprot id: A0A0F7K141
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS02515
gene id: 1543721:AAY24_RS02515
uniprot id: A0A0F7JVN0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS05260
gene id: 1543721:AAY24_RS05260
uniprot id: A0A0F7JW28
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1543721:AAY24 RS07130
gene id: 1543721:AAY24_RS07130
uniprot id: A0A0F7JUD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS15275
gene id: 1543721:AAY24_RS15275
uniprot id: A0A0F7K3I2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS03415
gene id: 1543721:AAY24_RS03415
uniprot id: A0A0F7JT05
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1543721:AAY24 RS13895
gene id: 1543721:AAY24_RS13895
uniprot id: A0A0F7K077
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1543721:AAY24 RS12585
gene id: 1543721:AAY24_RS12585
uniprot id: A0A0F7K280
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1543721:AAY24 RS01990
gene id: 1543721:AAY24_RS01990
uniprot id: A0A0F7JXH6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS10410
gene id: 1543721:AAY24_RS10410
uniprot id: A0A0F7K0Z8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1543721:AAY24 RS10235
gene id: 1543721:AAY24_RS10235
uniprot id: A0A0F7JZD3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS07265
gene id: 1543721:AAY24_RS07265
uniprot id: A0A0F7JZ91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1543721:AAY24 RS05200
gene id: 1543721:AAY24_RS05200
uniprot id: A0A0F7JYW7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1543721:AAY24 RS05775
gene id: 1543721:AAY24_RS05775
uniprot id: A0A0F7JYH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1543721:AAY24 RS08245
gene id: 1543721:AAY24_RS08245
uniprot id: A0A0F7JYI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1543721:AAY24 RS03100
gene id: 1543721:AAY24_RS03100
uniprot id: A0A0F7JVU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1543721:AAY24 RS02310
gene id: 1543721:AAY24_RS02310
uniprot id: A0A0F7JUS9
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1543721:AAY24 RS01885
gene id: 1543721:AAY24_RS01885
uniprot id: A0A0F7JWZ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1543721:AAY24 RS07390
gene id: 1543721:AAY24_RS07390
uniprot id: A0A0F7JY70
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1543721:AAY24 RS10405
gene id: 1543721:AAY24_RS10405
uniprot id: A0A0F7JW21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1543721:AAY24 RS10160
gene id: 1543721:AAY24_RS10160
uniprot id: A0A0F7JZD3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS07675
gene id: 1543721:AAY24_RS07675
uniprot id: A0A0F7JUK4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1543721:AAY24 RS11570
gene id: 1543721:AAY24_RS11570
uniprot id: A0A0F7K157
names: Similarity
messages: Belongs to the transposase 8 family.

1543721:AAY24 RS04780
gene id: 1543721:AAY24_RS04780
uniprot id: A0A0F7JTE9
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1543721:AAY24 RS13430
gene id: 1543721:AAY24_RS13430
uniprot id: A0A0F7JXJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

1543721:AAY24 RS06345
gene id: 1543721:AAY24_RS06345
uniprot id: A0A0F7JU05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1543721:AAY24 RS07610
gene id: 1543721:AAY24_RS07610
uniprot id: A0A0F7JZB6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1543721:AAY24 RS16680
gene id: 1543721:AAY24_RS16680
uniprot id: A0A0F7K3B5
names: Similarity
messages: Belongs to the NifX/NifY family.

1543721:AAY24 RS11310
gene id: 1543721:AAY24_RS11310
uniprot id: A0A0F7K1L0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1543721:AAY24 RS12860
gene id: 1543721:AAY24_RS12860
uniprot id: A0A0F7JZK7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1543721:AAY24 RS13225
gene id: 1543721:AAY24_RS13225
uniprot id: A0A0F7K1W2
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS04995
gene id: 1543721:AAY24_RS04995
uniprot id: A0A0F7JYT9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1543721:AAY24 RS01605
gene id: 1543721:AAY24_RS01605
uniprot id: A0A0F7JUF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1543721:AAY24 RS17150
gene id: 1543721:AAY24_RS17150
uniprot id: A0A0F7JZM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1543721:AAY24 RS13700
gene id: 1543721:AAY24_RS13700
uniprot id: A0A0F7K013
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS16075
gene id: 1543721:AAY24_RS16075
uniprot id: A0A0F7K345
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1543721:AAY24 RS08130
gene id: 1543721:AAY24_RS08130
uniprot id: A0A0F7JZG1
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS13830
gene id: 1543721:AAY24_RS13830
uniprot id: A0A0F7K061
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1543721:AAY24 RS10505
gene id: 1543721:AAY24_RS10505
uniprot id: A0A0F7JYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1543721:AAY24 RS14495
gene id: 1543721:AAY24_RS14495
uniprot id: A0A0F7K366
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1543721:AAY24 RS18120
gene id: 1543721:AAY24_RS18120
uniprot id: A0A0F7K055
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1543721:AAY24 RS16985
gene id: 1543721:AAY24_RS16985
uniprot id: A0A0F7JZL4
names: Similarity
messages: Belongs to the rubredoxin family.

1543721:AAY24 RS09810
gene id: 1543721:AAY24_RS09810
uniprot id: A0A0F7K2Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1543721:AAY24 RS14295
gene id: 1543721:AAY24_RS14295
uniprot id: A0A0F7K334
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.

1543721:AAY24 RS17230
gene id: 1543721:AAY24_RS17230
uniprot id: A0A0F7K497
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1543721:AAY24 RS16585
gene id: 1543721:AAY24_RS16585
uniprot id: A0A0F7K3A8
names: Similarity
messages: Belongs to the ArsC family.

1543721:AAY24 RS11835
gene id: 1543721:AAY24_RS11835
uniprot id: A0A0F7K165
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1543721:AAY24 RS08210
gene id: 1543721:AAY24_RS08210
uniprot id: A0A0F7JYI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1543721:AAY24 RS11820
gene id: 1543721:AAY24_RS11820
uniprot id: A0A0F7JZ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1543721:AAY24 RS14300
gene id: 1543721:AAY24_RS14300
uniprot id: A0A0F7K1A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1543721:AAY24 RS18020
gene id: 1543721:AAY24_RS18020
uniprot id: A0A0F7K043
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1543721:AAY24 RS00055
gene id: 1543721:AAY24_RS00055
uniprot id: A0A0F7JW97
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS05000
gene id: 1543721:AAY24_RS05000
uniprot id: A0A0F7JWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS04435
gene id: 1543721:AAY24_RS04435
uniprot id: A0A0F7JWH2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1543721:AAY24 RS04120
gene id: 1543721:AAY24_RS04120
uniprot id: A0A0F7JYH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1543721:AAY24 RS16735
gene id: 1543721:AAY24_RS16735
uniprot id: A0A0F7K2E6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1543721:AAY24 RS16965
gene id: 1543721:AAY24_RS16965
uniprot id: A0A0F7K1J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1543721:AAY24 RS06920
gene id: 1543721:AAY24_RS06920
uniprot id: A0A0F7JXY6
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1543721:AAY24 RS09475
gene id: 1543721:AAY24_RS09475
uniprot id: A0A0F7K029
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1543721:AAY24 RS03065
gene id: 1543721:AAY24_RS03065
uniprot id: A0A0F7K4V4
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1543721:AAY24 RS14575
gene id: 1543721:AAY24_RS14575
uniprot id: A0A0F7K0G6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1543721:AAY24 RS03330
gene id: 1543721:AAY24_RS03330
uniprot id: A0A0F7JXL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1543721:AAY24 RS14535
gene id: 1543721:AAY24_RS14535
uniprot id: A0A0F7JYA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1543721:AAY24 RS15355
gene id: 1543721:AAY24_RS15355
uniprot id: A0A0F7K1Q6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.
messages: Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.

1543721:AAY24 RS03640
gene id: 1543721:AAY24_RS03640
uniprot id: A0A0F7JY63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1543721:AAY24 RS06120
gene id: 1543721:AAY24_RS06120
uniprot id: A0A0F7JYN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS15815
gene id: 1543721:AAY24_RS15815
uniprot id: A0A0F7K215
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1543721:AAY24 RS13385
gene id: 1543721:AAY24_RS13385
uniprot id: A0A0F7JZV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1543721:AAY24 RS07320
gene id: 1543721:AAY24_RS07320
uniprot id: A0A0F7JY61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1543721:AAY24 RS01585
gene id: 1543721:AAY24_RS01585
uniprot id: A0A0F7JV93
names: Similarity
messages: Belongs to the selenium-binding protein family.

1543721:AAY24 RS07895
gene id: 1543721:AAY24_RS07895
uniprot id: A0A0F7JYE7
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1543721:AAY24 RS02430
gene id: 1543721:AAY24_RS02430
uniprot id: A0A0F7K436
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1543721:AAY24 RS14545
gene id: 1543721:AAY24_RS14545
uniprot id: A0A0F7K5S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1543721:AAY24 RS14040
gene id: 1543721:AAY24_RS14040
uniprot id: A0A0F7K138
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS01770
gene id: 1543721:AAY24_RS01770
uniprot id: A0A0F7JWX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1543721:AAY24 RS14355
gene id: 1543721:AAY24_RS14355
uniprot id: A0A0F7K1B1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1543721:AAY24 RS17050
gene id: 1543721:AAY24_RS17050
uniprot id: A0A0F7K479
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1543721:AAY24 RS12595
gene id: 1543721:AAY24_RS12595
uniprot id: A0A0F7K1K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1543721:AAY24 RS16010
gene id: 1543721:AAY24_RS16010
uniprot id: A0A0F7K231
names: Similarity
messages: Belongs to the FPG family.

1543721:AAY24 RS10325
gene id: 1543721:AAY24_RS10325
uniprot id: A0A0F7K0L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS09445
gene id: 1543721:AAY24_RS09445
uniprot id: A0A0F7K4P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS01180
gene id: 1543721:AAY24_RS01180
uniprot id: A0A0F7JWQ6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1543721:AAY24 RS10030
gene id: 1543721:AAY24_RS10030
uniprot id: A0A0F7JZB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS04545
gene id: 1543721:AAY24_RS04545
uniprot id: A0A0F7JYM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS06870
gene id: 1543721:AAY24_RS06870
uniprot id: A0A0F7JZ15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1543721:AAY24 RS16135
gene id: 1543721:AAY24_RS16135
uniprot id: A0A0F7K272
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1543721:AAY24 RS15425
gene id: 1543721:AAY24_RS15425
uniprot id: A0A0F7K1S5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1543721:AAY24 RS01705
gene id: 1543721:AAY24_RS01705
uniprot id: A0A0F7JUH0
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

1543721:AAY24 RS13250
gene id: 1543721:AAY24_RS13250
uniprot id: A0A0F7K415
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1543721:AAY24 RS19525
gene id: 1543721:AAY24_RS19525
uniprot id: A0A0F7JZQ7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1543721:AAY24 RS16470
gene id: 1543721:AAY24_RS16470
uniprot id: A0A0F7K2A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1543721:AAY24 RS00360
gene id: 1543721:AAY24_RS00360
uniprot id: A0A0F7JRH8
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1543721:AAY24 RS12880
gene id: 1543721:AAY24_RS12880
uniprot id: A0A0F7JX71
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1543721:AAY24 RS07570
gene id: 1543721:AAY24_RS07570
uniprot id: A0A0F7K005
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1543721:AAY24 RS03700
gene id: 1543721:AAY24_RS03700
uniprot id: A0A0F7JW48
names: Similarity
messages: Belongs to the peptidase S49 family.

1543721:AAY24 RS09275
gene id: 1543721:AAY24_RS09275
uniprot id: A0A0F7JXT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1543721:AAY24 RS12525
gene id: 1543721:AAY24_RS12525
uniprot id: A0A0F7K0A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1543721:AAY24 RS09335
gene id: 1543721:AAY24_RS09335
uniprot id: A0A0F7JYY9
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1543721:AAY24 RS04575
gene id: 1543721:AAY24_RS04575
uniprot id: A0A0F7JWM0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1543721:AAY24 RS07415
gene id: 1543721:AAY24_RS07415
uniprot id: A0A0F7JY75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1543721:AAY24 RS00780
gene id: 1543721:AAY24_RS00780
uniprot id: A0A0F7JWJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1543721:AAY24 RS17700
gene id: 1543721:AAY24_RS17700
uniprot id: A0A0F7K4G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1543721:AAY24 RS03110
gene id: 1543721:AAY24_RS03110
uniprot id: A0A0F7JSS7
names: Subcellular Location Annotation
messages: Bacterial microcompartment

1543721:AAY24 RS13625
gene id: 1543721:AAY24_RS13625
uniprot id: A0A0F7K216
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1543721:AAY24 RS09085
gene id: 1543721:AAY24_RS09085
uniprot id: A0A0F7JV86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1543721:AAY24 RS00175
gene id: 1543721:AAY24_RS00175
uniprot id: A0A0F7JUR4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1543721:AAY24 RS16170
gene id: 1543721:AAY24_RS16170
uniprot id: A0A0F7JZ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1543721:AAY24 RS07370
gene id: 1543721:AAY24_RS07370
uniprot id: A0A0F7JUH9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS15445
gene id: 1543721:AAY24_RS15445
uniprot id: A0A0F7JYV2
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1543721:AAY24 RS03815
gene id: 1543721:AAY24_RS03815
uniprot id: A0A0F7JT54
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1543721:AAY24 RS07045
gene id: 1543721:AAY24_RS07045
uniprot id: A0A0F7JZW9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS17590
gene id: 1543721:AAY24_RS17590
uniprot id: A0A0F7K3M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1543721:AAY24 RS01105
gene id: 1543721:AAY24_RS01105
uniprot id: A0A0F7JRT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1543721:AAY24 RS17545
gene id: 1543721:AAY24_RS17545
uniprot id: A0A0F7K4D8
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1543721:AAY24 RS10435
gene id: 1543721:AAY24_RS10435
uniprot id: A0A0F7JW23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1543721:AAY24 RS09310
gene id: 1543721:AAY24_RS09310
uniprot id: A0A0F7JYX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1543721:AAY24 RS14395
gene id: 1543721:AAY24_RS14395
uniprot id: A0A0F7K351
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1543721:AAY24 RS05400
gene id: 1543721:AAY24_RS05400
uniprot id: A0A0F7JYY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1543721:AAY24 RS04315
gene id: 1543721:AAY24_RS04315
uniprot id: A0A0F7JWF7
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS14050
gene id: 1543721:AAY24_RS14050
uniprot id: A0A0F7JY06
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS07690
gene id: 1543721:AAY24_RS07690
uniprot id: A0A0F7JYC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1543721:AAY24 RS05350
gene id: 1543721:AAY24_RS05350
uniprot id: A0A0F7JTM7
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1543721:AAY24 RS03865
gene id: 1543721:AAY24_RS03865
uniprot id: A0A0F7JW86
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1543721:AAY24 RS17550
gene id: 1543721:AAY24_RS17550
uniprot id: A0A0F7K2P6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS07995
gene id: 1543721:AAY24_RS07995
uniprot id: A0A0F7JXD6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1543721:AAY24 RS09440
gene id: 1543721:AAY24_RS09440
uniprot id: A0A0F7K025
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1543721:AAY24 RS14655
gene id: 1543721:AAY24_RS14655
uniprot id: A0A0F7K0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS01055
gene id: 1543721:AAY24_RS01055
uniprot id: A0A0F7JV18
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1543721:AAY24 RS07740
gene id: 1543721:AAY24_RS07740
uniprot id: A0A0F7JUN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1543721:AAY24 RS07405
gene id: 1543721:AAY24_RS07405
uniprot id: A0A0F7JX32
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

1543721:AAY24 RS06595
gene id: 1543721:AAY24_RS06595
uniprot id: A0A0F7JZR5
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1543721:AAY24 RS08155
gene id: 1543721:AAY24_RS08155
uniprot id: A0A0F7JZG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1543721:AAY24 RS13720
gene id: 1543721:AAY24_RS13720
uniprot id: A0A0F7JXQ4
names: Similarity
messages: Belongs to the fructosamine kinase family.

1543721:AAY24 RS07450
gene id: 1543721:AAY24_RS07450
uniprot id: A0A0F7JZZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1543721:AAY24 RS06640
gene id: 1543721:AAY24_RS06640
uniprot id: A0A0F7JU53
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1543721:AAY24 RS13395
gene id: 1543721:AAY24_RS13395
uniprot id: A0A0F7K0S7
names: Similarity
messages: Belongs to the glutamate synthase family.

1543721:AAY24 RS13770
gene id: 1543721:AAY24_RS13770
uniprot id: A0A0F7K2U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1543721:AAY24 RS17320
gene id: 1543721:AAY24_RS17320
uniprot id: A0A0F7K4B1
names: Similarity
messages: Belongs to the DsrF/TusC family.

1543721:AAY24 RS15300
gene id: 1543721:AAY24_RS15300
uniprot id: A0A0F7K3I4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1543721:AAY24 RS00825
gene id: 1543721:AAY24_RS00825
uniprot id: A0A0F7K0B0
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1543721:AAY24 RS11065
gene id: 1543721:AAY24_RS11065
uniprot id: A0A0F7JYJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1543721:AAY24 RS07685
gene id: 1543721:AAY24_RS07685
uniprot id: A0A0F7K021
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1543721:AAY24 RS03970
gene id: 1543721:AAY24_RS03970
uniprot id: A0A0F7JVQ3
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1543721:AAY24 RS11300
gene id: 1543721:AAY24_RS11300
uniprot id: A0A0F7JWH3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1543721:AAY24 RS10040
gene id: 1543721:AAY24_RS10040
uniprot id: A0A0F7JVX2
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1543721:AAY24 RS02090
gene id: 1543721:AAY24_RS02090
uniprot id: A0A0F7JX31
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1543721:AAY24 RS10535
gene id: 1543721:AAY24_RS10535
uniprot id: A0A0F7JW52
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1543721:AAY24 RS14570
gene id: 1543721:AAY24_RS14570
uniprot id: A0A0F7JYB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1543721:AAY24 RS01930
gene id: 1543721:AAY24_RS01930
uniprot id: A0A0F7JVF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1543721:AAY24 RS06275
gene id: 1543721:AAY24_RS06275
uniprot id: A0A0F7JXI9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1543721:AAY24 RS05270
gene id: 1543721:AAY24_RS05270
uniprot id: A0A0F7JWV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1543721:AAY24 RS12550
gene id: 1543721:AAY24_RS12550
uniprot id: A0A0F7JZ76
names: Similarity
messages: Belongs to the thioredoxin family.

1543721:AAY24 RS06300
gene id: 1543721:AAY24_RS06300
uniprot id: A0A0F7JWG1
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.

1543721:AAY24 RS08605
gene id: 1543721:AAY24_RS08605
uniprot id: A0A0F7JV07
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1543721:AAY24 RS18025
gene id: 1543721:AAY24_RS18025
uniprot id: A0A0F7K1Y8
names: Similarity
messages: Belongs to the aspartokinase family.

1543721:AAY24 RS13910
gene id: 1543721:AAY24_RS13910
uniprot id: A0A0F7K256
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1543721:AAY24 RS16115
gene id: 1543721:AAY24_RS16115
uniprot id: A0A0F7K175
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS08150
gene id: 1543721:AAY24_RS08150
uniprot id: A0A0F7JYH4
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS15825
gene id: 1543721:AAY24_RS15825
uniprot id: A0A0F7K453
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1543721:AAY24 RS07540
gene id: 1543721:AAY24_RS07540
uniprot id: A0A0F7JZB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS13185
gene id: 1543721:AAY24_RS13185
uniprot id: A0A0F7K2K6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS02980
gene id: 1543721:AAY24_RS02980
uniprot id: A0A0F7JXT8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1543721:AAY24 RS10930
gene id: 1543721:AAY24_RS10930
uniprot id: A0A0F7JYH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1543721:AAY24 RS11475
gene id: 1543721:AAY24_RS11475
uniprot id: A0A0F7JZU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1543721:AAY24 RS07315
gene id: 1543721:AAY24_RS07315
uniprot id: A0A0F7JZY2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1543721:AAY24 RS15910
gene id: 1543721:AAY24_RS15910
uniprot id: A0A0F7K157
names: Similarity
messages: Belongs to the transposase 8 family.

1543721:AAY24 RS13115
gene id: 1543721:AAY24_RS13115
uniprot id: A0A0F7JZR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1543721:AAY24 RS11400
gene id: 1543721:AAY24_RS11400
uniprot id: A0A0F7K107
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

1543721:AAY24 RS15290
gene id: 1543721:AAY24_RS15290
uniprot id: A0A0F7JYT2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS07810
gene id: 1543721:AAY24_RS07810
uniprot id: A0A0F7JZD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1543721:AAY24 RS08185
gene id: 1543721:AAY24_RS08185
uniprot id: A0A0F7K3Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1543721:AAY24 RS00315
gene id: 1543721:AAY24_RS00315
uniprot id: A0A0F7JUS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS08600
gene id: 1543721:AAY24_RS08600
uniprot id: A0A0F7JZK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1543721:AAY24 RS09590
gene id: 1543721:AAY24_RS09590
uniprot id: A0A0F7JZ60
names: Similarity
messages: Belongs to the pyruvate kinase family.

1543721:AAY24 RS13970
gene id: 1543721:AAY24_RS13970
uniprot id: A0A0F7K092
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1543721:AAY24 RS16905
gene id: 1543721:AAY24_RS16905
uniprot id: A0A0F7K461
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1543721:AAY24 RS00990
gene id: 1543721:AAY24_RS00990
uniprot id: A0A0F7JU51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1543721:AAY24 RS14455
gene id: 1543721:AAY24_RS14455
uniprot id: A0A0F7JY78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1543721:AAY24 RS09395
gene id: 1543721:AAY24_RS09395
uniprot id: A0A0F7JVE4
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1543721:AAY24 RS03350
gene id: 1543721:AAY24_RS03350
uniprot id: A0A0F7JXZ9
names: Similarity
messages: Belongs to the type III secretion exporter family.

1543721:AAY24 RS10265
gene id: 1543721:AAY24_RS10265
uniprot id: A0A0F7JZD5
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1543721:AAY24 RS06235
gene id: 1543721:AAY24_RS06235
uniprot id: A0A0F7JWF5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1543721:AAY24 RS07575
gene id: 1543721:AAY24_RS07575
uniprot id: A0A0F7JY94
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1543721:AAY24 RS08800
gene id: 1543721:AAY24_RS08800
uniprot id: A0A0F7K4M9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1543721:AAY24 RS00260
gene id: 1543721:AAY24_RS00260
uniprot id: A0A0F7JTR7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1543721:AAY24 RS00255
gene id: 1543721:AAY24_RS00255
uniprot id: A0A0F7JRG1
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1543721:AAY24 RS01735
gene id: 1543721:AAY24_RS01735
uniprot id: A0A0F7JXF8
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1543721:AAY24 RS15870
gene id: 1543721:AAY24_RS15870
uniprot id: A0A0F7K226
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1543721:AAY24 RS04580
gene id: 1543721:AAY24_RS04580
uniprot id: A0A0F7JY17
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1543721:AAY24 RS10115
gene id: 1543721:AAY24_RS10115
uniprot id: A0A0F7K119
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1543721:AAY24 RS07380
gene id: 1543721:AAY24_RS07380
uniprot id: A0A0F7JX30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1543721:AAY24 RS15210
gene id: 1543721:AAY24_RS15210
uniprot id: A0A0F7JYQ5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1543721:AAY24 RS07940
gene id: 1543721:AAY24_RS07940
uniprot id: A0A0F7JXD2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS10620
gene id: 1543721:AAY24_RS10620
uniprot id: A0A0F7K1A1
names: Similarity
messages: Belongs to the GSP E family.

1543721:AAY24 RS01860
gene id: 1543721:AAY24_RS01860
uniprot id: A0A0F7JS60
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS09025
gene id: 1543721:AAY24_RS09025
uniprot id: A0A0F7JYS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS05560
gene id: 1543721:AAY24_RS05560
uniprot id: A0A0F7JTP4
names: Similarity
messages: Belongs to the universal stress protein A family.

1543721:AAY24 RS08805
gene id: 1543721:AAY24_RS08805
uniprot id: A0A0F7JXM1
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1543721:AAY24 RS14485
gene id: 1543721:AAY24_RS14485
uniprot id: A0A0F7K0F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1543721:AAY24 RS14505
gene id: 1543721:AAY24_RS14505
uniprot id: A0A0F7K2D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1543721:AAY24 RS01060
gene id: 1543721:AAY24_RS01060
uniprot id: A0A0F7JWL8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS14175
gene id: 1543721:AAY24_RS14175
uniprot id: A0A0F7K290
names: Similarity
messages: Belongs to the GARS family.

1543721:AAY24 RS02775
gene id: 1543721:AAY24_RS02775
uniprot id: A0A0F7JXR4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1543721:AAY24 RS03280
gene id: 1543721:AAY24_RS03280
uniprot id: A0A0F7JSW3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1543721:AAY24 RS12060
gene id: 1543721:AAY24_RS12060
uniprot id: A0A0F7JWP8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1543721:AAY24 RS07500
gene id: 1543721:AAY24_RS07500
uniprot id: A0A0F7JY85
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS10745
gene id: 1543721:AAY24_RS10745
uniprot id: A0A0F7K1C2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS01345
gene id: 1543721:AAY24_RS01345
uniprot id: A0A0F7JX75
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1543721:AAY24 RS10330
gene id: 1543721:AAY24_RS10330
uniprot id: A0A0F7JW10
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1543721:AAY24 RS04865
gene id: 1543721:AAY24_RS04865
uniprot id: A0A0F7JYR0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1543721:AAY24 RS14435
gene id: 1543721:AAY24_RS14435
uniprot id: A0A0F7K0E7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1543721:AAY24 RS05755
gene id: 1543721:AAY24_RS05755
uniprot id: A0A0F7JWA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1543721:AAY24 RS13320
gene id: 1543721:AAY24_RS13320
uniprot id: A0A0F7JXH5
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1543721:AAY24 RS04955
gene id: 1543721:AAY24_RS04955
uniprot id: A0A0F7JW04
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1543721:AAY24 RS15745
gene id: 1543721:AAY24_RS15745
uniprot id: A0A0F7JZ52
names: Similarity
messages: Belongs to the UPF0102 family.

1543721:AAY24 RS10135
gene id: 1543721:AAY24_RS10135
uniprot id: A0A0F7JY92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1543721:AAY24 RS11290
gene id: 1543721:AAY24_RS11290
uniprot id: A0A0F7JZR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1543721:AAY24 RS04075
gene id: 1543721:AAY24_RS04075
uniprot id: A0A0F7JT92
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1543721:AAY24 RS06590
gene id: 1543721:AAY24_RS06590
uniprot id: A0A0F7JWU4
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS08845
gene id: 1543721:AAY24_RS08845
uniprot id: A0A0F7JYR4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS06940
gene id: 1543721:AAY24_RS06940
uniprot id: A0A0F7JX16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS15615
gene id: 1543721:AAY24_RS15615
uniprot id: A0A0F7K1W1
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1543721:AAY24 RS11745
gene id: 1543721:AAY24_RS11745
uniprot id: A0A0F7JWL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1543721:AAY24 RS03265
gene id: 1543721:AAY24_RS03265
uniprot id: A0A0F7JVW6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1543721:AAY24 RS06255
gene id: 1543721:AAY24_RS06255
uniprot id: A0A0F7K560
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1543721:AAY24 RS03750
gene id: 1543721:AAY24_RS03750
uniprot id: A0A0F7JY83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1543721:AAY24 RS12360
gene id: 1543721:AAY24_RS12360
uniprot id: A0A0F7JZ54
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1543721:AAY24 RS14425
gene id: 1543721:AAY24_RS14425
uniprot id: A0A0F7K2C1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS05025
gene id: 1543721:AAY24_RS05025
uniprot id: A0A0F7JWS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1543721:AAY24 RS07790
gene id: 1543721:AAY24_RS07790
uniprot id: A0A0F7JUN8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1543721:AAY24 RS16450
gene id: 1543721:AAY24_RS16450
uniprot id: A0A0F7JZF4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS00415
gene id: 1543721:AAY24_RS00415
uniprot id: A0A0F7JRK7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS09300
gene id: 1543721:AAY24_RS09300
uniprot id: A0A0F7JXU2
names: Similarity
messages: Belongs to the P(II) protein family.

1543721:AAY24 RS14555
gene id: 1543721:AAY24_RS14555
uniprot id: A0A0F7K1C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1543721:AAY24 RS15475
gene id: 1543721:AAY24_RS15475
uniprot id: A0A0F7K0U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1543721:AAY24 RS06980
gene id: 1543721:AAY24_RS06980
uniprot id: A0A0F7JX17
names: Subcellular Location Annotation
messages: Cell inner membrane

1543721:AAY24 RS12660
gene id: 1543721:AAY24_RS12660
uniprot id: A0A0F7K2C6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS01020
gene id: 1543721:AAY24_RS01020
uniprot id: A0A0F7JX44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS15240
gene id: 1543721:AAY24_RS15240
uniprot id: A0A0F7K0Q3
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1543721:AAY24 RS13010
gene id: 1543721:AAY24_RS13010
uniprot id: A0A0F7K5L3
names: Similarity
messages: Belongs to the UPF0178 family.

1543721:AAY24 RS11195
gene id: 1543721:AAY24_RS11195
uniprot id: A0A0F7K1I8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS06155
gene id: 1543721:AAY24_RS06155
uniprot id: A0A0F7JWE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1543721:AAY24 RS16750
gene id: 1543721:AAY24_RS16750
uniprot id: A0A0F7JZK0
names: Similarity
messages: Belongs to the NifZ family.

1543721:AAY24 RS05735
gene id: 1543721:AAY24_RS05735
uniprot id: A0A0F7JZ09
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1543721:AAY24 RS03680
gene id: 1543721:AAY24_RS03680
uniprot id: A0A0F7JT45
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1543721:AAY24 RS15250
gene id: 1543721:AAY24_RS15250
uniprot id: A0A0F7K1N1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS08070
gene id: 1543721:AAY24_RS08070
uniprot id: A0A0F7JUQ6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1543721:AAY24 RS18030
gene id: 1543721:AAY24_RS18030
uniprot id: A0A0F7K4M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1543721:AAY24 RS03840
gene id: 1543721:AAY24_RS03840
uniprot id: A0A0F7JXW8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1543721:AAY24 RS05185
gene id: 1543721:AAY24_RS05185
uniprot id: A0A0F7JYA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1543721:AAY24 RS10890
gene id: 1543721:AAY24_RS10890
uniprot id: A0A0F7JWB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1543721:AAY24 RS14825
gene id: 1543721:AAY24_RS14825
uniprot id: A0A0F7K1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1543721:AAY24 RS14475
gene id: 1543721:AAY24_RS14475
uniprot id: A0A0F7K2D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1543721:AAY24 RS02725
gene id: 1543721:AAY24_RS02725
uniprot id: A0A0F7JXC0
names: Similarity
messages: Belongs to the leucine-binding protein family.

1543721:AAY24 RS15125
gene id: 1543721:AAY24_RS15125
uniprot id: A0A0F7K2M1
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1543721:AAY24 RS06115
gene id: 1543721:AAY24_RS06115
uniprot id: A0A0F7JXC4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS10335
gene id: 1543721:AAY24_RS10335
uniprot id: A0A0F7JYA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

1543721:AAY24 RS04775
gene id: 1543721:AAY24_RS04775
uniprot id: A0A0F7JY33
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1543721:AAY24 RS05480
gene id: 1543721:AAY24_RS05480
uniprot id: A0A0F7JYY3
names: Similarity
messages: Belongs to the HsdR family.

1543721:AAY24 RS03965
gene id: 1543721:AAY24_RS03965
uniprot id: A0A0F7K462
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1543721:AAY24 RS14560
gene id: 1543721:AAY24_RS14560
uniprot id: A0A0F7K437
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1543721:AAY24 RS13680
gene id: 1543721:AAY24_RS13680
uniprot id: A0A0F7K2T3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1543721:AAY24 RS11160
gene id: 1543721:AAY24_RS11160
uniprot id: A0A0F7K1I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1543721:AAY24 RS08985
gene id: 1543721:AAY24_RS08985
uniprot id: A0A0F7JXQ9
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1543721:AAY24 RS07985
gene id: 1543721:AAY24_RS07985
uniprot id: A0A0F7K4K7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS13620
gene id: 1543721:AAY24_RS13620
uniprot id: A0A0F7K0W0
names: Similarity
messages: Belongs to the TrpC family.

1543721:AAY24 RS03545
gene id: 1543721:AAY24_RS03545
uniprot id: A0A0F7JVK0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1543721:AAY24 RS14290
gene id: 1543721:AAY24_RS14290
uniprot id: A0A0F7K0D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1543721:AAY24 RS15440
gene id: 1543721:AAY24_RS15440
uniprot id: A0A0F7K191
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1543721:AAY24 RS03770
gene id: 1543721:AAY24_RS03770
uniprot id: A0A0F7JVN1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1543721:AAY24 RS07285
gene id: 1543721:AAY24_RS07285
uniprot id: A0A0F7JZY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1543721:AAY24 RS02510
gene id: 1543721:AAY24_RS02510
uniprot id: A0A0F7JXP0
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1543721:AAY24 RS07525
gene id: 1543721:AAY24_RS07525
uniprot id: A0A0F7K0S6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1543721:AAY24 RS01955
gene id: 1543721:AAY24_RS01955
uniprot id: A0A0F7JXH3
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1543721:AAY24 RS16535
gene id: 1543721:AAY24_RS16535
uniprot id: A0A0F7JZH4
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

1543721:AAY24 RS13190
gene id: 1543721:AAY24_RS13190
uniprot id: A0A0F7K0P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1543721:AAY24 RS16625
gene id: 1543721:AAY24_RS16625
uniprot id: A0A0F7JZI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1543721:AAY24 RS05440
gene id: 1543721:AAY24_RS05440
uniprot id: A0A0F7JYE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1543721:AAY24 RS04855
gene id: 1543721:AAY24_RS04855
uniprot id: A0A0F7JTG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1543721:AAY24 RS10415
gene id: 1543721:AAY24_RS10415
uniprot id: A0A0F7JYA3
names: Similarity
messages: Belongs to the UPF0045 family.

1543721:AAY24 RS08685
gene id: 1543721:AAY24_RS08685
uniprot id: A0A0F7JZN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS08450
gene id: 1543721:AAY24_RS08450
uniprot id: A0A0F7JXH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1543721:AAY24 RS00440
gene id: 1543721:AAY24_RS00440
uniprot id: A0A0F7JWH0
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS05225
gene id: 1543721:AAY24_RS05225
uniprot id: A0A0F7JW24
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1543721:AAY24 RS15975
gene id: 1543721:AAY24_RS15975
uniprot id: A0A0F7K159
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS03445
gene id: 1543721:AAY24_RS03445
uniprot id: A0A0F7JVJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1543721:AAY24 RS03720
gene id: 1543721:AAY24_RS03720
uniprot id: A0A0F7JVM2
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1543721:AAY24 RS08265
gene id: 1543721:AAY24_RS08265
uniprot id: A0A0F7K073
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1543721:AAY24 RS04135
gene id: 1543721:AAY24_RS04135
uniprot id: A0A0F7JT96
names: Similarity
messages: Belongs to the ArsC family.

1543721:AAY24 RS15775
gene id: 1543721:AAY24_RS15775
uniprot id: A0A0F7JZ53
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS07930
gene id: 1543721:AAY24_RS07930
uniprot id: A0A0F7JZE3
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1543721:AAY24 RS04595
gene id: 1543721:AAY24_RS04595
uniprot id: A0A0F7JYN0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1543721:AAY24 RS11315
gene id: 1543721:AAY24_RS11315
uniprot id: A0A0F7JZR8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1543721:AAY24 RS02485
gene id: 1543721:AAY24_RS02485
uniprot id: A0A0F7JVM6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS15770
gene id: 1543721:AAY24_RS15770
uniprot id: A0A0F7K315
names: Similarity
messages: Belongs to the asparagine synthetase family.

1543721:AAY24 RS03420
gene id: 1543721:AAY24_RS03420
uniprot id: A0A0F7JVJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1543721:AAY24 RS11175
gene id: 1543721:AAY24_RS11175
uniprot id: A0A0F7K4S6
names: Similarity
messages: Belongs to the HesB/IscA family.

1543721:AAY24 RS07165
gene id: 1543721:AAY24_RS07165
uniprot id: A0A0F7JZ66
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1543721:AAY24 RS00190
gene id: 1543721:AAY24_RS00190
uniprot id: A0A0F7JRF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS13515
gene id: 1543721:AAY24_RS13515
uniprot id: A0A0F7JXL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1543721:AAY24 RS09195
gene id: 1543721:AAY24_RS09195
uniprot id: A0A0F7JXS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS08025
gene id: 1543721:AAY24_RS08025
uniprot id: A0A0F7K598
names: Similarity
messages: Belongs to the acylphosphatase family.

1543721:AAY24 RS00995
gene id: 1543721:AAY24_RS00995
uniprot id: A0A0F7JX41
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS06110
gene id: 1543721:AAY24_RS06110
uniprot id: A0A0F7JZ89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS13825
gene id: 1543721:AAY24_RS13825
uniprot id: A0A0F7K424
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1543721:AAY24 RS11720
gene id: 1543721:AAY24_RS11720
uniprot id: A0A0F7K5J1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1543721:AAY24 RS12355
gene id: 1543721:AAY24_RS12355
uniprot id: A0A0F7JWV5
names: Similarity
messages: Belongs to the Smg family.

1543721:AAY24 RS02340
gene id: 1543721:AAY24_RS02340
uniprot id: A0A0F7JUT2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1543721:AAY24 RS00540
gene id: 1543721:AAY24_RS00540
uniprot id: A0A0F7JRM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1543721:AAY24 RS04530
gene id: 1543721:AAY24_RS04530
uniprot id: A0A0F7JTB9
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1543721:AAY24 RS14775
gene id: 1543721:AAY24_RS14775
uniprot id: A0A0F7K0K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS10705
gene id: 1543721:AAY24_RS10705
uniprot id: A0A0F7JZI0
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1543721:AAY24 RS16345
gene id: 1543721:AAY24_RS16345
uniprot id: A0A0F7K375
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS15085
gene id: 1543721:AAY24_RS15085
uniprot id: A0A0F7K3E1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1543721:AAY24 RS03635
gene id: 1543721:AAY24_RS03635
uniprot id: A0A0F7JVK9
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS14390
gene id: 1543721:AAY24_RS14390
uniprot id: A0A0F7K0E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1543721:AAY24 RS15485
gene id: 1543721:AAY24_RS15485
uniprot id: A0A0F7K1T5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

1543721:AAY24 RS01970
gene id: 1543721:AAY24_RS01970
uniprot id: A0A0F7JS72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1543721:AAY24 RS05115
gene id: 1543721:AAY24_RS05115
uniprot id: A0A0F7JYV1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1543721:AAY24 RS15790
gene id: 1543721:AAY24_RS15790
uniprot id: A0A0F7K214
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1543721:AAY24 RS01080
gene id: 1543721:AAY24_RS01080
uniprot id: A0A0F7JV22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1543721:AAY24 RS10840
gene id: 1543721:AAY24_RS10840
uniprot id: A0A0F7JYG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1543721:AAY24 RS01315
gene id: 1543721:AAY24_RS01315
uniprot id: A0A0F7K0C7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1543721:AAY24 RS16490
gene id: 1543721:AAY24_RS16490
uniprot id: A0A0F7K1C4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1543721:AAY24 RS17390
gene id: 1543721:AAY24_RS17390
uniprot id: A0A0F7JZQ2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1543721:AAY24 RS09820
gene id: 1543721:AAY24_RS09820
uniprot id: A0A0F7K0V7
names: Similarity
messages: Belongs to the UPF0235 family.

1543721:AAY24 RS05335
gene id: 1543721:AAY24_RS05335
uniprot id: A0A0F7JWW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1543721:AAY24 RS14615
gene id: 1543721:AAY24_RS14615
uniprot id: A0A0F7K2F3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1543721:AAY24 RS07865
gene id: 1543721:AAY24_RS07865
uniprot id: A0A0F7JZD8
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1543721:AAY24 RS13540
gene id: 1543721:AAY24_RS13540
uniprot id: A0A0F7JXL6
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.

1543721:AAY24 RS08885
gene id: 1543721:AAY24_RS08885
uniprot id: A0A0F7JV46
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1543721:AAY24 RS13505
gene id: 1543721:AAY24_RS13505
uniprot id: A0A0F7K0T9
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

1543721:AAY24 RS05425
gene id: 1543721:AAY24_RS05425
uniprot id: A0A0F7JW81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS02755
gene id: 1543721:AAY24_RS02755
uniprot id: A0A0F7JSI9
names: Similarity
messages: Belongs to the leucine-binding protein family.

1543721:AAY24 RS03295
gene id: 1543721:AAY24_RS03295
uniprot id: A0A0F7JVW9
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS14415
gene id: 1543721:AAY24_RS14415
uniprot id: A0A0F7K1B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1543721:AAY24 RS03455
gene id: 1543721:AAY24_RS03455
uniprot id: A0A0F7JW34
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1543721:AAY24 RS10340
gene id: 1543721:AAY24_RS10340
uniprot id: A0A0F7K148
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1543721:AAY24 RS07635
gene id: 1543721:AAY24_RS07635
uniprot id: A0A0F7K012
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1543721:AAY24 RS08275
gene id: 1543721:AAY24_RS08275
uniprot id: A0A0F7JZG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1543721:AAY24 RS07585
gene id: 1543721:AAY24_RS07585
uniprot id: A0A0F7JUJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1543721:AAY24 RS01805
gene id: 1543721:AAY24_RS01805
uniprot id: A0A0F7JS52
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1543721:AAY24 RS16035
gene id: 1543721:AAY24_RS16035
uniprot id: A0A0F7K235
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS15820
gene id: 1543721:AAY24_RS15820
uniprot id: A0A0F7K317
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1543721:AAY24 RS13040
gene id: 1543721:AAY24_RS13040
uniprot id: A0A0F7K2I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1543721:AAY24 RS00350
gene id: 1543721:AAY24_RS00350
uniprot id: A0A0F7JUT0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1543721:AAY24 RS08655
gene id: 1543721:AAY24_RS08655
uniprot id: A0A0F7JZM8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1543721:AAY24 RS07650
gene id: 1543721:AAY24_RS07650
uniprot id: A0A0F7JUK1
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1543721:AAY24 RS15320
gene id: 1543721:AAY24_RS15320
uniprot id: A0A0F7K0R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1543721:AAY24 RS07780
gene id: 1543721:AAY24_RS07780
uniprot id: A0A0F7JYD9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1543721:AAY24 RS00905
gene id: 1543721:AAY24_RS00905
uniprot id: A0A0F7JUZ6
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS01905
gene id: 1543721:AAY24_RS01905
uniprot id: A0A0F7JVF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1543721:AAY24 RS12855
gene id: 1543721:AAY24_RS12855
uniprot id: A0A0F7JX66
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS09920
gene id: 1543721:AAY24_RS09920
uniprot id: A0A0F7JVV9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1543721:AAY24 RS16675
gene id: 1543721:AAY24_RS16675
uniprot id: A0A0F7K2D7
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1543721:AAY24 RS11930
gene id: 1543721:AAY24_RS11930
uniprot id: A0A0F7K020
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1543721:AAY24 RS14760
gene id: 1543721:AAY24_RS14760
uniprot id: A0A0F7K4Y6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1543721:AAY24 RS00985
gene id: 1543721:AAY24_RS00985
uniprot id: A0A0F7JRT1
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1543721:AAY24 RS04900
gene id: 1543721:AAY24_RS04900
uniprot id: A0A0F7JW02
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS00915
gene id: 1543721:AAY24_RS00915
uniprot id: A0A0F7JRS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1543721:AAY24 RS12575
gene id: 1543721:AAY24_RS12575
uniprot id: A0A0F7JWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1543721:AAY24 RS12045
gene id: 1543721:AAY24_RS12045
uniprot id: A0A0F7K036
names: Similarity
messages: Belongs to the GSP E family.

1543721:AAY24 RS11045
gene id: 1543721:AAY24_RS11045
uniprot id: A0A0F7JZN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

1543721:AAY24 RS13195
gene id: 1543721:AAY24_RS13195
uniprot id: A0A0F7K1W0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1543721:AAY24 RS00225
gene id: 1543721:AAY24_RS00225
uniprot id: A0A0F7JRF4
names: Similarity
messages: Belongs to the HupF/HypC family.

1543721:AAY24 RS02590
gene id: 1543721:AAY24_RS02590
uniprot id: A0A0F7JXP7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1543721:AAY24 RS11695
gene id: 1543721:AAY24_RS11695
uniprot id: A0A0F7K135
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1543721:AAY24 RS13340
gene id: 1543721:AAY24_RS13340
uniprot id: A0A0F7K0S1
names: Similarity
messages: Belongs to the citrate synthase family.

1543721:AAY24 RS08715
gene id: 1543721:AAY24_RS08715
uniprot id: A0A0F7JZN7
names: Similarity
messages: Belongs to the GST superfamily.

1543721:AAY24 RS03175
gene id: 1543721:AAY24_RS03175
uniprot id: A0A0F7JXW6
names: Similarity
messages: Belongs to the peptidase A31 family.

1543721:AAY24 RS08580
gene id: 1543721:AAY24_RS08580
uniprot id: A0A0F7JV02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS10420
gene id: 1543721:AAY24_RS10420
uniprot id: A0A0F7K171
names: Similarity
messages: Belongs to the UPF0047 family.

1543721:AAY24 RS07445
gene id: 1543721:AAY24_RS07445
uniprot id: A0A0F7JX36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1543721:AAY24 RS02750
gene id: 1543721:AAY24_RS02750
uniprot id: A0A0F7JXC5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS12760
gene id: 1543721:AAY24_RS12760
uniprot id: A0A0F7K0I0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS06160
gene id: 1543721:AAY24_RS06160
uniprot id: A0A0F7JZ97
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1543721:AAY24 RS09795
gene id: 1543721:AAY24_RS09795
uniprot id: A0A0F7JZ96
names: Similarity
messages: Belongs to the GSP E family.

1543721:AAY24 RS16895
gene id: 1543721:AAY24_RS16895
uniprot id: A0A0F7JZK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1543721:AAY24 RS05190
gene id: 1543721:AAY24_RS05190
uniprot id: A0A0F7JTL1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1543721:AAY24 RS13545
gene id: 1543721:AAY24_RS13545
uniprot id: A0A0F7JZZ1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1543721:AAY24 RS01790
gene id: 1543721:AAY24_RS01790
uniprot id: A0A0F7JXG1
names: Similarity
messages: Belongs to the SCO1/2 family.

1543721:AAY24 RS14325
gene id: 1543721:AAY24_RS14325
uniprot id: A0A0F7K339
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1543721:AAY24 RS15305
gene id: 1543721:AAY24_RS15305
uniprot id: A0A0F7K1P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1543721:AAY24 RS09635
gene id: 1543721:AAY24_RS09635
uniprot id: A0A0F7JY00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS03285
gene id: 1543721:AAY24_RS03285
uniprot id: A0A0F7JVF6
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

1543721:AAY24 RS11295
gene id: 1543721:AAY24_RS11295
uniprot id: A0A0F7K0Z9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1543721:AAY24 RS18090
gene id: 1543721:AAY24_RS18090
uniprot id: A0A0F7K3W7
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS09840
gene id: 1543721:AAY24_RS09840
uniprot id: A0A0F7JY43
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS03520
gene id: 1543721:AAY24_RS03520
uniprot id: A0A0F7JW37
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1543721:AAY24 RS17180
gene id: 1543721:AAY24_RS17180
uniprot id: A0A0F7JZM6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1543721:AAY24 RS15520
gene id: 1543721:AAY24_RS15520
uniprot id: A0A0F7K3M1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1543721:AAY24 RS01890
gene id: 1543721:AAY24_RS01890
uniprot id: A0A0F7JS63
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1543721:AAY24 RS06805
gene id: 1543721:AAY24_RS06805
uniprot id: A0A0F7JZU6
names: Similarity
messages: Belongs to the PspA/IM30 family.

1543721:AAY24 RS03740
gene id: 1543721:AAY24_RS03740
uniprot id: A0A0F7JT48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1543721:AAY24 RS06605
gene id: 1543721:AAY24_RS06605
uniprot id: A0A0F7JYW6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1543721:AAY24 RS15285
gene id: 1543721:AAY24_RS15285
uniprot id: A0A0F7K2Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1543721:AAY24 RS18240
gene id: 1543721:AAY24_RS18240
uniprot id: A0A0F7K577
names: Similarity
messages: Belongs to the GSP E family.

1543721:AAY24 RS16730
gene id: 1543721:AAY24_RS16730
uniprot id: A0A0F7K446
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

1543721:AAY24 RS11085
gene id: 1543721:AAY24_RS11085
uniprot id: A0A0F7JWC9
names: Similarity
messages: Belongs to the PhoH family.

1543721:AAY24 RS11840
gene id: 1543721:AAY24_RS11840
uniprot id: A0A0F7JWM5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1543721:AAY24 RS04795
gene id: 1543721:AAY24_RS04795
uniprot id: A0A0F7JWP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

1543721:AAY24 RS04020
gene id: 1543721:AAY24_RS04020
uniprot id: A0A0F7JT84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1543721:AAY24 RS13475
gene id: 1543721:AAY24_RS13475
uniprot id: A0A0F7K2P9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1543721:AAY24 RS07980
gene id: 1543721:AAY24_RS07980
uniprot id: A0A0F7JZE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1543721:AAY24 RS08550
gene id: 1543721:AAY24_RS08550
uniprot id: A0A0F7JUZ9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1543721:AAY24 RS14630
gene id: 1543721:AAY24_RS14630
uniprot id: A0A0F7K386
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS08140
gene id: 1543721:AAY24_RS08140
uniprot id: A0A0F7JXE3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1543721:AAY24 RS17940
gene id: 1543721:AAY24_RS17940
uniprot id: A0A0F7K4K9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1543721:AAY24 RS03105
gene id: 1543721:AAY24_RS03105
uniprot id: A0A0F7JXH8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1543721:AAY24 RS01920
gene id: 1543721:AAY24_RS01920
uniprot id: A0A0F7JUP3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS13805
gene id: 1543721:AAY24_RS13805
uniprot id: A0A0F7K2V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1543721:AAY24 RS10490
gene id: 1543721:AAY24_RS10490
uniprot id: A0A0F7JZE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS00370
gene id: 1543721:AAY24_RS00370
uniprot id: A0A0F7JWU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1543721:AAY24 RS03130
gene id: 1543721:AAY24_RS03130
uniprot id: A0A0F7JXI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS04640
gene id: 1543721:AAY24_RS04640
uniprot id: A0A0F7JWM7
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1543721:AAY24 RS03760
gene id: 1543721:AAY24_RS03760
uniprot id: A0A0F7JXW1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1543721:AAY24 RS05780
gene id: 1543721:AAY24_RS05780
uniprot id: A0A0F7JTT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS12120
gene id: 1543721:AAY24_RS12120
uniprot id: A0A0F7JWQ4
names: Similarity
messages: Belongs to the HdrA family.

1543721:AAY24 RS11880
gene id: 1543721:AAY24_RS11880
uniprot id: A0A0F7K011
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1543721:AAY24 RS02185
gene id: 1543721:AAY24_RS02185
uniprot id: A0A0F7JS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1543721:AAY24 RS15035
gene id: 1543721:AAY24_RS15035
uniprot id: A0A0F7K2K9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS09035
gene id: 1543721:AAY24_RS09035
uniprot id: A0A0F7JV74
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1543721:AAY24 RS17450
gene id: 1543721:AAY24_RS17450
uniprot id: A0A0F7K3K4
names: Similarity
messages: Belongs to the transposase 8 family.

1543721:AAY24 RS04860
gene id: 1543721:AAY24_RS04860
uniprot id: A0A0F7JW01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1543721:AAY24 RS13950
gene id: 1543721:AAY24_RS13950
uniprot id: A0A0F7K2X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1543721:AAY24 RS01140
gene id: 1543721:AAY24_RS01140
uniprot id: A0A0F7JX54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1543721:AAY24 RS02320
gene id: 1543721:AAY24_RS02320
uniprot id: A0A0F7JXN0
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1543721:AAY24 RS17210
gene id: 1543721:AAY24_RS17210
uniprot id: A0A0F7K3H3
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1543721:AAY24 RS06365
gene id: 1543721:AAY24_RS06365
uniprot id: A0A0F7JXK4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1543721:AAY24 RS06470
gene id: 1543721:AAY24_RS06470
uniprot id: A0A0F7JZJ6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1543721:AAY24 RS12230
gene id: 1543721:AAY24_RS12230
uniprot id: A0A0F7K1E4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1543721:AAY24 RS16125
gene id: 1543721:AAY24_RS16125
uniprot id: A0A0F7K194
names: Similarity
messages: Belongs to the PhoH family.

1543721:AAY24 RS11190
gene id: 1543721:AAY24_RS11190
uniprot id: A0A0F7JYL2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS17205
gene id: 1543721:AAY24_RS17205
uniprot id: A0A0F7K2K1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1543721:AAY24 RS16620
gene id: 1543721:AAY24_RS16620
uniprot id: A0A0F7K3B0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-101 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1543721:AAY24 RS17285
gene id: 1543721:AAY24_RS17285
uniprot id: A0A0F7JZN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1543721:AAY24 RS11660
gene id: 1543721:AAY24_RS11660
uniprot id: A0A0F7JZY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1543721:AAY24 RS15315
gene id: 1543721:AAY24_RS15315
uniprot id: A0A0F7JYT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1543721:AAY24 RS03185
gene id: 1543721:AAY24_RS03185
uniprot id: A0A0F7JXJ1
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1543721:AAY24 RS12330
gene id: 1543721:AAY24_RS12330
uniprot id: A0A0F7JZ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1543721:AAY24 RS00865
gene id: 1543721:AAY24_RS00865
uniprot id: A0A0F7JRS4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1543721:AAY24 RS02235
gene id: 1543721:AAY24_RS02235
uniprot id: A0A0F7JSA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

1543721:AAY24 RS05235
gene id: 1543721:AAY24_RS05235
uniprot id: A0A0F7JYX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1543721:AAY24 RS12710
gene id: 1543721:AAY24_RS12710
uniprot id: A0A0F7K1N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1543721:AAY24 RS14360
gene id: 1543721:AAY24_RS14360
uniprot id: A0A0F7K2B7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1543721:AAY24 RS15855
gene id: 1543721:AAY24_RS15855
uniprot id: A0A0F7JZ59
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS04960
gene id: 1543721:AAY24_RS04960
uniprot id: A0A0F7JYT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1543721:AAY24 RS09030
gene id: 1543721:AAY24_RS09030
uniprot id: A0A0F7JZU5
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS09140
gene id: 1543721:AAY24_RS09140
uniprot id: A0A0F7JYU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1543721:AAY24 RS08455
gene id: 1543721:AAY24_RS08455
uniprot id: A0A0F7K093
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1543721:AAY24 RS15230
gene id: 1543721:AAY24_RS15230
uniprot id: A0A0F7K2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1543721:AAY24 RS15985
gene id: 1543721:AAY24_RS15985
uniprot id: A0A0F7K230
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS06175
gene id: 1543721:AAY24_RS06175
uniprot id: A0A0F7JTY0
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS15700
gene id: 1543721:AAY24_RS15700
uniprot id: A0A0F7K2Y2
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS01895
gene id: 1543721:AAY24_RS01895
uniprot id: A0A0F7JUP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1543721:AAY24 RS11705
gene id: 1543721:AAY24_RS11705
uniprot id: A0A0F7K344
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1543721:AAY24 RS15645
gene id: 1543721:AAY24_RS15645
uniprot id: A0A0F7K1W5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1543721:AAY24 RS05275
gene id: 1543721:AAY24_RS05275
uniprot id: A0A0F7JYC2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1543721:AAY24 RS09860
gene id: 1543721:AAY24_RS09860
uniprot id: A0A0F7K0C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1543721:AAY24 RS11885
gene id: 1543721:AAY24_RS11885
uniprot id: A0A0F7K174
names: Similarity
messages: Belongs to the peptidase U62 family.

1543721:AAY24 RS10120
gene id: 1543721:AAY24_RS10120
uniprot id: A0A0F7JZB9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1543721:AAY24 RS09620
gene id: 1543721:AAY24_RS09620
uniprot id: A0A0F7K089
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1543721:AAY24 RS03595
gene id: 1543721:AAY24_RS03595
uniprot id: A0A0F7JXT9
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1543721:AAY24 RS05605
gene id: 1543721:AAY24_RS05605
uniprot id: A0A0F7JYZ1
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS16405
gene id: 1543721:AAY24_RS16405
uniprot id: A0A0F7K408
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1543721:AAY24 RS07260
gene id: 1543721:AAY24_RS07260
uniprot id: A0A0F7JY48
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1543721:AAY24 RS15655
gene id: 1543721:AAY24_RS15655
uniprot id: A0A0F7JZ02
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS02940
gene id: 1543721:AAY24_RS02940
uniprot id: A0A0F7JXE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS02080
gene id: 1543721:AAY24_RS02080
uniprot id: A0A0F7JXJ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1543721:AAY24 RS10895
gene id: 1543721:AAY24_RS10895
uniprot id: A0A0F7JYH1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS16055
gene id: 1543721:AAY24_RS16055
uniprot id: A0A0F7K168
names: Similarity
messages: Belongs to the UPF0260 family.

1543721:AAY24 RS06580
gene id: 1543721:AAY24_RS06580
uniprot id: A0A0F7JYW1
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

1543721:AAY24 RS11270
gene id: 1543721:AAY24_RS11270
uniprot id: A0A0F7JYM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1543721:AAY24 RS08660
gene id: 1543721:AAY24_RS08660
uniprot id: A0A0F7JV15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS07830
gene id: 1543721:AAY24_RS07830
uniprot id: A0A0F7K038
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1543721:AAY24 RS03920
gene id: 1543721:AAY24_RS03920
uniprot id: A0A0F7JT59
names: Similarity
messages: Belongs to the YkuD family.

1543721:AAY24 RS12895
gene id: 1543721:AAY24_RS12895
uniprot id: A0A0F7K0K6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1543721:AAY24 RS11830
gene id: 1543721:AAY24_RS11830
uniprot id: A0A0F7K002
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

1543721:AAY24 RS07050
gene id: 1543721:AAY24_RS07050
uniprot id: A0A0F7JY24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS02815
gene id: 1543721:AAY24_RS02815
uniprot id: A0A0F7JXD3
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

1543721:AAY24 RS13965
gene id: 1543721:AAY24_RS13965
uniprot id: A0A0F7JXY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1543721:AAY24 RS02365
gene id: 1543721:AAY24_RS02365
uniprot id: A0A0F7JSB7
names: Similarity
messages: Belongs to the histone deacetylase family.

1543721:AAY24 RS00895
gene id: 1543721:AAY24_RS00895
uniprot id: A0A0F7JU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

1543721:AAY24 RS07015
gene id: 1543721:AAY24_RS07015
uniprot id: A0A0F7JZW8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS05700
gene id: 1543721:AAY24_RS05700
uniprot id: A0A0F7K3J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1543721:AAY24 RS14510
gene id: 1543721:AAY24_RS14510
uniprot id: A0A0F7JY90
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1543721:AAY24 RS07975
gene id: 1543721:AAY24_RS07975
uniprot id: A0A0F7JYF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1543721:AAY24 RS12875
gene id: 1543721:AAY24_RS12875
uniprot id: A0A0F7K1P8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1543721:AAY24 RS06200
gene id: 1543721:AAY24_RS06200
uniprot id: A0A0F7JTY2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1543721:AAY24 RS05450
gene id: 1543721:AAY24_RS05450
uniprot id: A0A0F7JW87
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1543721:AAY24 RS15435
gene id: 1543721:AAY24_RS15435
uniprot id: A0A0F7K2T1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1543721:AAY24 RS11915
gene id: 1543721:AAY24_RS11915
uniprot id: A0A0F7JWN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1543721:AAY24 RS08400
gene id: 1543721:AAY24_RS08400
uniprot id: A0A0F7K084
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1543721:AAY24 RS08160
gene id: 1543721:AAY24_RS08160
uniprot id: A0A0F7JUT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1543721:AAY24 RS08555
gene id: 1543721:AAY24_RS08555
uniprot id: A0A0F7JXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1543721:AAY24 RS09595
gene id: 1543721:AAY24_RS09595
uniprot id: A0A0F7K086
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1543721:AAY24 RS07850
gene id: 1543721:AAY24_RS07850
uniprot id: A0A0F7JXB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1543721:AAY24 RS11135
gene id: 1543721:AAY24_RS11135
uniprot id: A0A0F7JZP0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1543721:AAY24 RS00640
gene id: 1543721:AAY24_RS00640
uniprot id: A0A0F7K3Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1543721:AAY24 RS09665
gene id: 1543721:AAY24_RS09665
uniprot id: A0A0F7K0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1543721:AAY24 RS13060
gene id: 1543721:AAY24_RS13060
uniprot id: A0A0F7JZQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1543721:AAY24 RS08545
gene id: 1543721:AAY24_RS08545
uniprot id: A0A0F7JZJ4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1543721:AAY24 RS10565
gene id: 1543721:AAY24_RS10565
uniprot id: A0A0F7K0P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1543721:AAY24 RS08165
gene id: 1543721:AAY24_RS08165
uniprot id: A0A0F7JXE5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1543721:AAY24 RS12685
gene id: 1543721:AAY24_RS12685
uniprot id: A0A0F7JZI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS13035
gene id: 1543721:AAY24_RS13035
uniprot id: A0A0F7JZP7
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS07640
gene id: 1543721:AAY24_RS07640
uniprot id: A0A0F7JYB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1543721:AAY24 RS17500
gene id: 1543721:AAY24_RS17500
uniprot id: A0A0F7JZR7
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS04060
gene id: 1543721:AAY24_RS04060
uniprot id: A0A0F7JYG1
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1543721:AAY24 RS09870
gene id: 1543721:AAY24_RS09870
uniprot id: A0A0F7JY49
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1543721:AAY24 RS13555
gene id: 1543721:AAY24_RS13555
uniprot id: A0A0F7K0U3
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1543721:AAY24 RS02110
gene id: 1543721:AAY24_RS02110
uniprot id: A0A0F7JVH7
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1543721:AAY24 RS15215
gene id: 1543721:AAY24_RS15215
uniprot id: A0A0F7K0P7
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1543721:AAY24 RS08635
gene id: 1543721:AAY24_RS08635
uniprot id: A0A0F7JXJ5
names: Similarity
messages: Belongs to the HesB/IscA family.

1543721:AAY24 RS14130
gene id: 1543721:AAY24_RS14130
uniprot id: A0A0F7K286
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1543721:AAY24 RS12730
gene id: 1543721:AAY24_RS12730
uniprot id: A0A0F7K0H8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1543721:AAY24 RS14945
gene id: 1543721:AAY24_RS14945
uniprot id: A0A0F7JYL4
names: Similarity
messages: Belongs to the histone deacetylase family.

1543721:AAY24 RS02860
gene id: 1543721:AAY24_RS02860
uniprot id: A0A0F7JSN6
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1543721:AAY24 RS07535
gene id: 1543721:AAY24_RS07535
uniprot id: A0A0F7JY89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1543721:AAY24 RS15755
gene id: 1543721:AAY24_RS15755
uniprot id: A0A0F7K151
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1543721:AAY24 RS16375
gene id: 1543721:AAY24_RS16375
uniprot id: A0A0F7K2A1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS03485
gene id: 1543721:AAY24_RS03485
uniprot id: A0A0F7JY42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1543721:AAY24 RS17005
gene id: 1543721:AAY24_RS17005
uniprot id: A0A0F7K2I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1543721:AAY24 RS07200
gene id: 1543721:AAY24_RS07200
uniprot id: A0A0F7JZ68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1543721:AAY24 RS10500
gene id: 1543721:AAY24_RS10500
uniprot id: A0A0F7JW30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1543721:AAY24 RS15480
gene id: 1543721:AAY24_RS15480
uniprot id: A0A0F7K3L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1543721:AAY24 RS00595
gene id: 1543721:AAY24_RS00595
uniprot id: A0A0F7JRP7
names: Similarity
messages: Belongs to the UPF0229 family.

1543721:AAY24 RS00660
gene id: 1543721:AAY24_RS00660
uniprot id: A0A0F7K078
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1543721:AAY24 RS07515
gene id: 1543721:AAY24_RS07515
uniprot id: A0A0F7JUJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1543721:AAY24 RS10375
gene id: 1543721:AAY24_RS10375
uniprot id: A0A0F7K0L7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1543721:AAY24 RS15765
gene id: 1543721:AAY24_RS15765
uniprot id: A0A0F7K213
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1543721:AAY24 RS00630
gene id: 1543721:AAY24_RS00630
uniprot id: A0A0F7K306
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1543721:AAY24 RS08055
gene id: 1543721:AAY24_RS08055
uniprot id: A0A0F7K4L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1543721:AAY24 RS12430
gene id: 1543721:AAY24_RS12430
uniprot id: A0A0F7K1H8
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

1543721:AAY24 RS01880
gene id: 1543721:AAY24_RS01880
uniprot id: A0A0F7JVE6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1543721:AAY24 RS17080
gene id: 1543721:AAY24_RS17080
uniprot id: A0A0F7K2I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1543721:AAY24 RS17930
gene id: 1543721:AAY24_RS17930
uniprot id: A0A0F7K031
names: Caution
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS03835
gene id: 1543721:AAY24_RS03835
uniprot id: A0A0F7K380
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS16350
gene id: 1543721:AAY24_RS16350
uniprot id: A0A0F7JZC7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1543721:AAY24 RS14595
gene id: 1543721:AAY24_RS14595
uniprot id: A0A0F7JYB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1543721:AAY24 RS07470
gene id: 1543721:AAY24_RS07470
uniprot id: A0A0F7JUI7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS09815
gene id: 1543721:AAY24_RS09815
uniprot id: A0A0F7JY39
names: Similarity
messages: Belongs to the YggT family.

1543721:AAY24 RS18010
gene id: 1543721:AAY24_RS18010
uniprot id: A0A0F7K2X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1543721:AAY24 RS07665
gene id: 1543721:AAY24_RS07665
uniprot id: A0A0F7JYC3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1543721:AAY24 RS15190
gene id: 1543721:AAY24_RS15190
uniprot id: A0A0F7K0P5
names: Similarity
messages: Belongs to the citrate synthase family.

1543721:AAY24 RS08530
gene id: 1543721:AAY24_RS08530
uniprot id: A0A0F7JXH7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1543721:AAY24 RS05220
gene id: 1543721:AAY24_RS05220
uniprot id: A0A0F7K3D6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1543721:AAY24 RS15685
gene id: 1543721:AAY24_RS15685
uniprot id: A0A0F7K0Z0
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS11775
gene id: 1543721:AAY24_RS11775
uniprot id: A0A0F7JZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1543721:AAY24 RS06505
gene id: 1543721:AAY24_RS06505
uniprot id: A0A0F7JZP6
names: Similarity
messages: Belongs to the AOR/FOR family.

1543721:AAY24 RS12740
gene id: 1543721:AAY24_RS12740
uniprot id: A0A0F7JX55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS16555
gene id: 1543721:AAY24_RS16555
uniprot id: A0A0F7K3A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS08215
gene id: 1543721:AAY24_RS08215
uniprot id: A0A0F7JZG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1543721:AAY24 RS17805
gene id: 1543721:AAY24_RS17805
uniprot id: A0A0F7K4I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1543721:AAY24 RS12535
gene id: 1543721:AAY24_RS12535
uniprot id: A0A0F7K1J4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1543721:AAY24 RS13900
gene id: 1543721:AAY24_RS13900
uniprot id: A0A0F7K2W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1543721:AAY24 RS07820
gene id: 1543721:AAY24_RS07820
uniprot id: A0A0F7JUP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1543721:AAY24 RS06080
gene id: 1543721:AAY24_RS06080
uniprot id: A0A0F7JZ67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1543721:AAY24 RS00195
gene id: 1543721:AAY24_RS00195
uniprot id: A0A0F7JTR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS03395
gene id: 1543721:AAY24_RS03395
uniprot id: A0A0F7JVH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1543721:AAY24 RS03055
gene id: 1543721:AAY24_RS03055
uniprot id: A0A0F7JVB4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1543721:AAY24 RS05750
gene id: 1543721:AAY24_RS05750
uniprot id: A0A0F7JTS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1543721:AAY24 RS06950
gene id: 1543721:AAY24_RS06950
uniprot id: A0A0F7JZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS13685
gene id: 1543721:AAY24_RS13685
uniprot id: A0A0F7K0X0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1543721:AAY24 RS08665
gene id: 1543721:AAY24_RS08665
uniprot id: A0A0F7JXK1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1543721:AAY24 RS09400
gene id: 1543721:AAY24_RS09400
uniprot id: A0A0F7JXV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1543721:AAY24 RS01825
gene id: 1543721:AAY24_RS01825
uniprot id: A0A0F7JVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS06910
gene id: 1543721:AAY24_RS06910
uniprot id: A0A0F7JX13
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1543721:AAY24 RS05020
gene id: 1543721:AAY24_RS05020
uniprot id: A0A0F7JYU3
names: Similarity
messages: Belongs to the YciI family.

1543721:AAY24 RS03320
gene id: 1543721:AAY24_RS03320
uniprot id: A0A0F7JXY3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1543721:AAY24 RS02435
gene id: 1543721:AAY24_RS02435
uniprot id: A0A0F7JXN8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1543721:AAY24 RS02935
gene id: 1543721:AAY24_RS02935
uniprot id: A0A0F7JVS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS16880
gene id: 1543721:AAY24_RS16880
uniprot id: A0A0F7K458
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1543721:AAY24 RS14030
gene id: 1543721:AAY24_RS14030
uniprot id: A0A0F7K2Z2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1543721:AAY24 RS02325
gene id: 1543721:AAY24_RS02325
uniprot id: A0A0F7JVK6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1543721:AAY24 RS09375
gene id: 1543721:AAY24_RS09375
uniprot id: A0A0F7JYZ4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1543721:AAY24 RS10150
gene id: 1543721:AAY24_RS10150
uniprot id: A0A0F7K0H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1543721:AAY24 RS11090
gene id: 1543721:AAY24_RS11090
uniprot id: A0A0F7JYJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1543721:AAY24 RS17520
gene id: 1543721:AAY24_RS17520
uniprot id: A0A0F7K4D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS09605
gene id: 1543721:AAY24_RS09605
uniprot id: A0A0F7JXZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1543721:AAY24 RS02680
gene id: 1543721:AAY24_RS02680
uniprot id: A0A0F7JXQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1543721:AAY24 RS02705
gene id: 1543721:AAY24_RS02705
uniprot id: A0A0F7JSH8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS15990
gene id: 1543721:AAY24_RS15990
uniprot id: A0A0F7K330
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS09360
gene id: 1543721:AAY24_RS09360
uniprot id: A0A0F7K0J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1543721:AAY24 RS12140
gene id: 1543721:AAY24_RS12140
uniprot id: A0A0F7K1C8
names: Similarity
messages: Belongs to the hemerythrin family.

1543721:AAY24 RS10885
gene id: 1543721:AAY24_RS10885
uniprot id: A0A0F7K0T2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1543721:AAY24 RS13070
gene id: 1543721:AAY24_RS13070
uniprot id: A0A0F7K0M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1543721:AAY24 RS04480
gene id: 1543721:AAY24_RS04480
uniprot id: A0A0F7JYL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1543721:AAY24 RS11800
gene id: 1543721:AAY24_RS11800
uniprot id: A0A0F7K1V1
names: Similarity
messages: Belongs to the UPF0758 family.

1543721:AAY24 RS16340
gene id: 1543721:AAY24_RS16340
uniprot id: A0A0F7K297
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1543721:AAY24 RS01650
gene id: 1543721:AAY24_RS01650
uniprot id: A0A0F7JVA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

1543721:AAY24 RS16070
gene id: 1543721:AAY24_RS16070
uniprot id: A0A0F7K240
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1543721:AAY24 RS03575
gene id: 1543721:AAY24_RS03575
uniprot id: A0A0F7JVK3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1543721:AAY24 RS12335
gene id: 1543721:AAY24_RS12335
uniprot id: A0A0F7K246
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1543721:AAY24 RS08790
gene id: 1543721:AAY24_RS08790
uniprot id: A0A0F7K3R3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1543721:AAY24 RS01460
gene id: 1543721:AAY24_RS01460
uniprot id: A0A0F7JX95
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1543721:AAY24 RS11055
gene id: 1543721:AAY24_RS11055
uniprot id: A0A0F7JWC5
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1543721:AAY24 RS08675
gene id: 1543721:AAY24_RS08675
uniprot id: A0A0F7K3Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1543721:AAY24 RS10285
gene id: 1543721:AAY24_RS10285
uniprot id: A0A0F7JVZ5
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1543721:AAY24 RS03690
gene id: 1543721:AAY24_RS03690
uniprot id: A0A0F7JVL8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1543721:AAY24 RS17165
gene id: 1543721:AAY24_RS17165
uniprot id: A0A0F7K493
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1543721:AAY24 RS01335
gene id: 1543721:AAY24_RS01335
uniprot id: A0A0F7JRW1
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS18125
gene id: 1543721:AAY24_RS18125
uniprot id: A0A0F7K203
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS00310
gene id: 1543721:AAY24_RS00310
uniprot id: A0A0F7JWT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS13985
gene id: 1543721:AAY24_RS13985
uniprot id: A0A0F7K265
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1543721:AAY24 RS10240
gene id: 1543721:AAY24_RS10240
uniprot id: A0A0F7K0J4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS07765
gene id: 1543721:AAY24_RS07765
uniprot id: A0A0F7JUN5
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1543721:AAY24 RS16465
gene id: 1543721:AAY24_RS16465
uniprot id: A0A0F7K413
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1543721:AAY24 RS15670
gene id: 1543721:AAY24_RS15670
uniprot id: A0A0F7K1X1
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1543721:AAY24 RS13875
gene id: 1543721:AAY24_RS13875
uniprot id: A0A0F7K254
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1543721:AAY24 RS14950
gene id: 1543721:AAY24_RS14950
uniprot id: A0A0F7K0M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS04000
gene id: 1543721:AAY24_RS04000
uniprot id: A0A0F7JVQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1543721:AAY24 RS08005
gene id: 1543721:AAY24_RS08005
uniprot id: A0A0F7K062
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS00920
gene id: 1543721:AAY24_RS00920
uniprot id: A0A0F7JU43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS02950
gene id: 1543721:AAY24_RS02950
uniprot id: A0A0F7JV92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS01090
gene id: 1543721:AAY24_RS01090
uniprot id: A0A0F7K269
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS14090
gene id: 1543721:AAY24_RS14090
uniprot id: A0A0F7K300
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS05210
gene id: 1543721:AAY24_RS05210
uniprot id: A0A0F7JYB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1543721:AAY24 RS00520
gene id: 1543721:AAY24_RS00520
uniprot id: A0A0F7K075
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS13675
gene id: 1543721:AAY24_RS13675
uniprot id: A0A0F7K007
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1543721:AAY24 RS04565
gene id: 1543721:AAY24_RS04565
uniprot id: A0A0F7JVY4
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1543721:AAY24 RS06085
gene id: 1543721:AAY24_RS06085
uniprot id: A0A0F7JXB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1543721:AAY24 RS09585
gene id: 1543721:AAY24_RS09585
uniprot id: A0A0F7K0R2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1543721:AAY24 RS11970
gene id: 1543721:AAY24_RS11970
uniprot id: A0A0F7JWP1
names: Similarity
messages: Belongs to the P(II) protein family.

1543721:AAY24 RS11170
gene id: 1543721:AAY24_RS11170
uniprot id: A0A0F7K0X9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1543721:AAY24 RS14830
gene id: 1543721:AAY24_RS14830
uniprot id: A0A0F7K2H6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS11520
gene id: 1543721:AAY24_RS11520
uniprot id: A0A0F7K336
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS12160
gene id: 1543721:AAY24_RS12160
uniprot id: A0A0F7K050
names: Similarity
messages: Belongs to the archease family.

1543721:AAY24 RS11690
gene id: 1543721:AAY24_RS11690
uniprot id: A0A0F7JZY5
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

1543721:AAY24 RS08640
gene id: 1543721:AAY24_RS08640
uniprot id: A0A0F7K0A5
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1543721:AAY24 RS11610
gene id: 1543721:AAY24_RS11610
uniprot id: A0A0F7K1R8
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1543721:AAY24 RS00730
gene id: 1543721:AAY24_RS00730
uniprot id: A0A0F7JU14
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

1543721:AAY24 RS13520
gene id: 1543721:AAY24_RS13520
uniprot id: A0A0F7JZY7
names: Similarity
messages: Belongs to the MotB family.

1543721:AAY24 RS12270
gene id: 1543721:AAY24_RS12270
uniprot id: A0A0F7K5K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1543721:AAY24 RS17555
gene id: 1543721:AAY24_RS17555
uniprot id: A0A0F7K3L9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS01910
gene id: 1543721:AAY24_RS01910
uniprot id: A0A0F7JWZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1543721:AAY24 RS15960
gene id: 1543721:AAY24_RS15960
uniprot id: A0A0F7K326
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS11215
gene id: 1543721:AAY24_RS11215
uniprot id: A0A0F7JYL7
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS14585
gene id: 1543721:AAY24_RS14585
uniprot id: A0A0F7K1D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1543721:AAY24 RS09645
gene id: 1543721:AAY24_RS09645
uniprot id: A0A0F7JZ78
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS02405
gene id: 1543721:AAY24_RS02405
uniprot id: A0A0F7JXN7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1543721:AAY24 RS17415
gene id: 1543721:AAY24_RS17415
uniprot id: A0A0F7K3J9
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS13990
gene id: 1543721:AAY24_RS13990
uniprot id: A0A0F7JXY5
names: Similarity
messages: Belongs to the MoaD family.

1543721:AAY24 RS14465
gene id: 1543721:AAY24_RS14465
uniprot id: A0A0F7K361
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1543721:AAY24 RS09420
gene id: 1543721:AAY24_RS09420
uniprot id: A0A0F7JVE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1543721:AAY24 RS04660
gene id: 1543721:AAY24_RS04660
uniprot id: A0A0F7JTD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1543721:AAY24 RS16995
gene id: 1543721:AAY24_RS16995
uniprot id: A0A0F7K1J8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1543721:AAY24 RS09640
gene id: 1543721:AAY24_RS09640
uniprot id: A0A0F7K0T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1543721:AAY24 RS11465
gene id: 1543721:AAY24_RS11465
uniprot id: A0A0F7JYV0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS04005
gene id: 1543721:AAY24_RS04005
uniprot id: A0A0F7JYD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1543721:AAY24 RS06410
gene id: 1543721:AAY24_RS06410
uniprot id: A0A0F7JU13
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS10820
gene id: 1543721:AAY24_RS10820
uniprot id: A0A0F7JZL3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1543721:AAY24 RS15630
gene id: 1543721:AAY24_RS15630
uniprot id: A0A0F7K503
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS07600
gene id: 1543721:AAY24_RS07600
uniprot id: A0A0F7K008
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1543721:AAY24 RS00125
gene id: 1543721:AAY24_RS00125
uniprot id: A0A0F7JWA8
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1543721:AAY24 RS12030
gene id: 1543721:AAY24_RS12030
uniprot id: A0A0F7JZ34
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1543721:AAY24 RS08095
gene id: 1543721:AAY24_RS08095
uniprot id: A0A0F7JZF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS14095
gene id: 1543721:AAY24_RS14095
uniprot id: A0A0F7K147
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1543721:AAY24 RS14255
gene id: 1543721:AAY24_RS14255
uniprot id: A0A0F7K0D2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1543721:AAY24 RS14310
gene id: 1543721:AAY24_RS14310
uniprot id: A0A0F7K2A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1543721:AAY24 RS15840
gene id: 1543721:AAY24_RS15840
uniprot id: A0A0F7K3T7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1543721:AAY24 RS14605
gene id: 1543721:AAY24_RS14605
uniprot id: A0A0F7K382
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1543721:AAY24 RS01830
gene id: 1543721:AAY24_RS01830
uniprot id: A0A0F7JWY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1543721:AAY24 RS15880
gene id: 1543721:AAY24_RS15880
uniprot id: A0A0F7JZ61
names: Similarity
messages: Belongs to the DEAD box helicase family.

1543721:AAY24 RS16900
gene id: 1543721:AAY24_RS16900
uniprot id: A0A0F7K1I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1543721:AAY24 RS16565
gene id: 1543721:AAY24_RS16565
uniprot id: A0A0F7K1D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS01015
gene id: 1543721:AAY24_RS01015
uniprot id: A0A0F7JU57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS08225
gene id: 1543721:AAY24_RS08225
uniprot id: A0A0F7K4L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1543721:AAY24 RS08310
gene id: 1543721:AAY24_RS08310
uniprot id: A0A0F7JUU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1543721:AAY24 RS02930
gene id: 1543721:AAY24_RS02930
uniprot id: A0A0F7JXS7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1543721:AAY24 RS09715
gene id: 1543721:AAY24_RS09715
uniprot id: A0A0F7JVP4
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1543721:AAY24 RS17910
gene id: 1543721:AAY24_RS17910
uniprot id: A0A0F7K1X0
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

1543721:AAY24 RS14315
gene id: 1543721:AAY24_RS14315
uniprot id: A0A0F7JY57
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1543721:AAY24 RS12805
gene id: 1543721:AAY24_RS12805
uniprot id: A0A0F7JX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1543721:AAY24 RS15720
gene id: 1543721:AAY24_RS15720
uniprot id: A0A0F7K3B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1543721:AAY24 RS09405
gene id: 1543721:AAY24_RS09405
uniprot id: A0A0F7K0J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1543721:AAY24 RS02215
gene id: 1543721:AAY24_RS02215
uniprot id: A0A0F7JUS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS09765
gene id: 1543721:AAY24_RS09765
uniprot id: A0A0F7K0B1
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1543721:AAY24 RS14220
gene id: 1543721:AAY24_RS14220
uniprot id: A0A0F7JY41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1543721:AAY24 RS16320
gene id: 1543721:AAY24_RS16320
uniprot id: A0A0F7K1A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS07000
gene id: 1543721:AAY24_RS07000
uniprot id: A0A0F7JUB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1543721:AAY24 RS06135
gene id: 1543721:AAY24_RS06135
uniprot id: A0A0F7JZ93
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS17795
gene id: 1543721:AAY24_RS17795
uniprot id: A0A0F7K009
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1543721:AAY24 RS07275
gene id: 1543721:AAY24_RS07275
uniprot id: A0A0F7JUF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1543721:AAY24 RS10130
gene id: 1543721:AAY24_RS10130
uniprot id: A0A0F7JVY2
names: Similarity
messages: Belongs to the peptidase M16 family.

1543721:AAY24 RS18055
gene id: 1543721:AAY24_RS18055
uniprot id: A0A0F7K3W1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1543721:AAY24 RS00375
gene id: 1543721:AAY24_RS00375
uniprot id: A0A0F7K302
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1543721:AAY24 RS04145
gene id: 1543721:AAY24_RS04145
uniprot id: A0A0F7JYH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1543721:AAY24 RS07330
gene id: 1543721:AAY24_RS07330
uniprot id: A0A0F7JUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1543721:AAY24 RS01570
gene id: 1543721:AAY24_RS01570
uniprot id: A0A0F7JUD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1543721:AAY24 RS03040
gene id: 1543721:AAY24_RS03040
uniprot id: A0A0F7JVU1
names: Similarity
messages: Belongs to the EutP/PduV family.

1543721:AAY24 RS13870
gene id: 1543721:AAY24_RS13870
uniprot id: A0A0F7K114
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1543721:AAY24 RS15620
gene id: 1543721:AAY24_RS15620
uniprot id: A0A0F7K2W4
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1543721:AAY24 RS16525
gene id: 1543721:AAY24_RS16525
uniprot id: A0A0F7K2B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS16875
gene id: 1543721:AAY24_RS16875
uniprot id: A0A0F7K1H9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS07825
gene id: 1543721:AAY24_RS07825
uniprot id: A0A0F7JXB3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1543721:AAY24 RS08595
gene id: 1543721:AAY24_RS08595
uniprot id: A0A0F7JYP2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1543721:AAY24 RS02735
gene id: 1543721:AAY24_RS02735
uniprot id: A0A0F7JV52
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1543721:AAY24 RS15260
gene id: 1543721:AAY24_RS15260
uniprot id: A0A0F7K2P8
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1543721:AAY24 RS06090
gene id: 1543721:AAY24_RS06090
uniprot id: A0A0F7K2Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1543721:AAY24 RS11980
gene id: 1543721:AAY24_RS11980
uniprot id: A0A0F7K1Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1543721:AAY24 RS15040
gene id: 1543721:AAY24_RS15040
uniprot id: A0A0F7JYN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1543721:AAY24 RS16160
gene id: 1543721:AAY24_RS16160
uniprot id: A0A0F7K277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1543721:AAY24 RS08620
gene id: 1543721:AAY24_RS08620
uniprot id: A0A0F7JYP8
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1543721:AAY24 RS01480
gene id: 1543721:AAY24_RS01480
uniprot id: A0A0F7JUC0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1543721:AAY24 RS05345
gene id: 1543721:AAY24_RS05345
uniprot id: A0A0F7JYD2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1543721:AAY24 RS00080
gene id: 1543721:AAY24_RS00080
uniprot id: A0A0F7JUM9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1543721:AAY24 RS11440
gene id: 1543721:AAY24_RS11440
uniprot id: A0A0F7K1M9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1543721:AAY24 RS09060
gene id: 1543721:AAY24_RS09060
uniprot id: A0A0F7JV79
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1543721:AAY24 RS15000
gene id: 1543721:AAY24_RS15000
uniprot id: A0A0F7K2K3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS13655
gene id: 1543721:AAY24_RS13655
uniprot id: A0A0F7K220
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1543721:AAY24 RS04065
gene id: 1543721:AAY24_RS04065
uniprot id: A0A0F7JWE2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1543721:AAY24 RS17705
gene id: 1543721:AAY24_RS17705
uniprot id: A0A0F7K2S0
names: Similarity
messages: Belongs to the GppA/Ppx family.

1543721:AAY24 RS13275
gene id: 1543721:AAY24_RS13275
uniprot id: A0A0F7JZT4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1543721:AAY24 RS13695
gene id: 1543721:AAY24_RS13695
uniprot id: A0A0F7JXQ0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1543721:AAY24 RS03755
gene id: 1543721:AAY24_RS03755
uniprot id: A0A0F7JW56
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1543721:AAY24 RS11810
gene id: 1543721:AAY24_RS11810
uniprot id: A0A0F7K150
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1543721:AAY24 RS06600
gene id: 1543721:AAY24_RS06600
uniprot id: A0A0F7JXP8
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1543721:AAY24 RS00745
gene id: 1543721:AAY24_RS00745
uniprot id: A0A0F7JWI9
names: Similarity
messages: Belongs to the peptidase A31 family.

1543721:AAY24 RS12560
gene id: 1543721:AAY24_RS12560
uniprot id: A0A0F7K0A9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS17075
gene id: 1543721:AAY24_RS17075
uniprot id: A0A0F7K482
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1543721:AAY24 RS07875
gene id: 1543721:AAY24_RS07875
uniprot id: A0A0F7JXC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1543721:AAY24 RS09705
gene id: 1543721:AAY24_RS09705
uniprot id: A0A0F7K0A4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1543721:AAY24 RS02335
gene id: 1543721:AAY24_RS02335
uniprot id: A0A0F7JSB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1543721:AAY24 RS15635
gene id: 1543721:AAY24_RS15635
uniprot id: A0A0F7K0X5
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS04750
gene id: 1543721:AAY24_RS04750
uniprot id: A0A0F7JY31
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1543721:AAY24 RS17160
gene id: 1543721:AAY24_RS17160
uniprot id: A0A0F7K5Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1543721:AAY24 RS16800
gene id: 1543721:AAY24_RS16800
uniprot id: A0A0F7K480
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1543721:AAY24 RS08120
gene id: 1543721:AAY24_RS08120
uniprot id: A0A0F7JYG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS13835
gene id: 1543721:AAY24_RS13835
uniprot id: A0A0F7K2V8
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS06775
gene id: 1543721:AAY24_RS06775
uniprot id: A0A0F7JZU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1543721:AAY24 RS03780
gene id: 1543721:AAY24_RS03780
uniprot id: A0A0F7JW61
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1543721:AAY24 RS06095
gene id: 1543721:AAY24_RS06095
uniprot id: A0A0F7JYM6
names: Similarity
messages: Belongs to the TrpF family.

1543721:AAY24 RS08390
gene id: 1543721:AAY24_RS08390
uniprot id: A0A0F7JUV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS07120
gene id: 1543721:AAY24_RS07120
uniprot id: A0A0F7JY32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1543721:AAY24 RS03625
gene id: 1543721:AAY24_RS03625
uniprot id: A0A0F7JXU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1543721:AAY24 RS08320
gene id: 1543721:AAY24_RS08320
uniprot id: A0A0F7K080
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1543721:AAY24 RS08510
gene id: 1543721:AAY24_RS08510
uniprot id: A0A0F7JZI9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1543721:AAY24 RS10945
gene id: 1543721:AAY24_RS10945
uniprot id: A0A0F7JZM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1543721:AAY24 RS10025
gene id: 1543721:AAY24_RS10025
uniprot id: A0A0F7K0Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS07860
gene id: 1543721:AAY24_RS07860
uniprot id: A0A0F7JYE5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1543721:AAY24 RS08290
gene id: 1543721:AAY24_RS08290
uniprot id: A0A0F7JXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1543721:AAY24 RS00890
gene id: 1543721:AAY24_RS00890
uniprot id: A0A0F7JRS6
names: Subcellular Location Annotation
messages: Cell inner membrane

1543721:AAY24 RS14145
gene id: 1543721:AAY24_RS14145
uniprot id: A0A0F7K308
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1543721:AAY24 RS01425
gene id: 1543721:AAY24_RS01425
uniprot id: A0A0F7JV69
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1543721:AAY24 RS08180
gene id: 1543721:AAY24_RS08180
uniprot id: A0A0F7JZG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1543721:AAY24 RS15205
gene id: 1543721:AAY24_RS15205
uniprot id: A0A0F7K2N8
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

1543721:AAY24 RS03245
gene id: 1543721:AAY24_RS03245
uniprot id: A0A0F7JXK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1543721:AAY24 RS08330
gene id: 1543721:AAY24_RS08330
uniprot id: A0A0F7JZG8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1543721:AAY24 RS05820
gene id: 1543721:AAY24_RS05820
uniprot id: A0A0F7JYI1
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS03660
gene id: 1543721:AAY24_RS03660
uniprot id: A0A0F7JVL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1543721:AAY24 RS15740
gene id: 1543721:AAY24_RS15740
uniprot id: A0A0F7K314
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1543721:AAY24 RS08045
gene id: 1543721:AAY24_RS08045
uniprot id: A0A0F7K066
names: Similarity
messages: Belongs to the WrbA family.

1543721:AAY24 RS11965
gene id: 1543721:AAY24_RS11965
uniprot id: A0A0F7K184
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1543721:AAY24 RS01965
gene id: 1543721:AAY24_RS01965
uniprot id: A0A0F7JX01
names: Subcellular Location Annotation
messages: Cytoplasm

1543721:AAY24 RS10175
gene id: 1543721:AAY24_RS10175
uniprot id: A0A0F7K0H5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1543721:AAY24 RS09975
gene id: 1543721:AAY24_RS09975
uniprot id: A0A0F7JZB0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1543721:AAY24 RS03375
gene id: 1543721:AAY24_RS03375
uniprot id: A0A0F7JY04
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1543721:AAY24 RS15325
gene id: 1543721:AAY24_RS15325
uniprot id: A0A0F7K3J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1543721:AAY24 RS09255
gene id: 1543721:AAY24_RS09255
uniprot id: A0A0F7K0I7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1543721:AAY24 RS17765
gene id: 1543721:AAY24_RS17765
uniprot id: A0A0F7K3Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1543721:AAY24 RS14450
gene id: 1543721:AAY24_RS14450
uniprot id: A0A0F7K2C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1543721:AAY24 RS09315
gene id: 1543721:AAY24_RS09315
uniprot id: A0A0F7K004
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1543721:AAY24 RS06660
gene id: 1543721:AAY24_RS06660
uniprot id: A0A0F7JWU6
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1543721:AAY24 RS15850
gene id: 1543721:AAY24_RS15850
uniprot id: A0A0F7K318
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1543721:AAY24 RS17585
gene id: 1543721:AAY24_RS17585
uniprot id: A0A0F7K2Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS08335
gene id: 1543721:AAY24_RS08335
uniprot id: A0A0F7JUU9
names: Similarity
messages: Belongs to the thioredoxin family.

1543721:AAY24 RS02505
gene id: 1543721:AAY24_RS02505
uniprot id: A0A0F7K440
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1543721:AAY24 RS02440
gene id: 1543721:AAY24_RS02440
uniprot id: A0A0F7JVM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1543721:AAY24 RS11320
gene id: 1543721:AAY24_RS11320
uniprot id: A0A0F7K101
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1543721:AAY24 RS15005
gene id: 1543721:AAY24_RS15005
uniprot id: A0A0F7JYM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS06830
gene id: 1543721:AAY24_RS06830
uniprot id: A0A0F7JZV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1543721:AAY24 RS17800
gene id: 1543721:AAY24_RS17800
uniprot id: A0A0F7K1V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1543721:AAY24 RS07835
gene id: 1543721:AAY24_RS07835
uniprot id: A0A0F7JYE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1543721:AAY24 RS00580
gene id: 1543721:AAY24_RS00580
uniprot id: A0A0F7JWY0
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS11865
gene id: 1543721:AAY24_RS11865
uniprot id: A0A0F7JWM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1543721:AAY24 RS11205
gene id: 1543721:AAY24_RS11205
uniprot id: A0A0F7K0Y8
names: Similarity
messages: Belongs to the SCO1/2 family.

1543721:AAY24 RS02155
gene id: 1543721:AAY24_RS02155
uniprot id: A0A0F7JUR5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1543721:AAY24 RS13630
gene id: 1543721:AAY24_RS13630
uniprot id: A0A0F7JXM9
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1543721:AAY24 RS07870
gene id: 1543721:AAY24_RS07870
uniprot id: A0A0F7JUP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1543721:AAY24 RS11845
gene id: 1543721:AAY24_RS11845
uniprot id: A0A0F7JZ19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1543721:AAY24 RS10360
gene id: 1543721:AAY24_RS10360
uniprot id: A0A0F7JYA1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1543721:AAY24 RS14810
gene id: 1543721:AAY24_RS14810
uniprot id: A0A0F7JYG2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1543721:AAY24 RS15080
gene id: 1543721:AAY24_RS15080
uniprot id: A0A0F7K0N4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1543721:AAY24 RS09285
gene id: 1543721:AAY24_RS09285
uniprot id: A0A0F7JYW8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1543721:AAY24 RS12800
gene id: 1543721:AAY24_RS12800
uniprot id: A0A0F7K1P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1543721:AAY24 RS13410
gene id: 1543721:AAY24_RS13410
uniprot id: A0A0F7JZV7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1543721:AAY24 RS11920
gene id: 1543721:AAY24_RS11920
uniprot id: A0A0F7JZ30
names: Similarity
messages: Belongs to the hemerythrin family.

1543721:AAY24 RS00230
gene id: 1543721:AAY24_RS00230
uniprot id: A0A0F7JTR5
names: Similarity
messages: Belongs to the HypD family.

1543721:AAY24 RS16395
gene id: 1543721:AAY24_RS16395
uniprot id: A0A0F7K3E0
names: Similarity
messages: Belongs to the glutamate synthase family.

1543721:AAY24 RS14625
gene id: 1543721:AAY24_RS14625
uniprot id: A0A0F7K0H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1543721:AAY24 RS04715
gene id: 1543721:AAY24_RS04715
uniprot id: A0A0F7JWN4
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1543721:AAY24 RS04945
gene id: 1543721:AAY24_RS04945
uniprot id: A0A0F7JY59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1543721:AAY24 RS06715
gene id: 1543721:AAY24_RS06715
uniprot id: A0A0F7JWU9
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS12615
gene id: 1543721:AAY24_RS12615
uniprot id: A0A0F7K0B8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1543721:AAY24 RS14815
gene id: 1543721:AAY24_RS14815
uniprot id: A0A0F7K0K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1543721:AAY24 RS07775
gene id: 1543721:AAY24_RS07775
uniprot id: A0A0F7K030
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1543721:AAY24 RS05895
gene id: 1543721:AAY24_RS05895
uniprot id: A0A0F7JZ27
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1543721:AAY24 RS12885
gene id: 1543721:AAY24_RS12885
uniprot id: A0A0F7JZM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1543721:AAY24 RS16715
gene id: 1543721:AAY24_RS16715
uniprot id: A0A0F7K3B8
names: Similarity
messages: Belongs to the HesB/IscA family.

1543721:AAY24 RS11805
gene id: 1543721:AAY24_RS11805
uniprot id: A0A0F7JZZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1543721:AAY24 RS04615
gene id: 1543721:AAY24_RS04615
uniprot id: A0A0F7JTC9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1543721:AAY24 RS08680
gene id: 1543721:AAY24_RS08680
uniprot id: A0A0F7JYQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1543721:AAY24 RS09770
gene id: 1543721:AAY24_RS09770
uniprot id: A0A0F7JVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1543721:AAY24 RS11700
gene id: 1543721:AAY24_RS11700
uniprot id: A0A0F7JWK8
names: Cofactor
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1543721:AAY24 RS06185
gene id: 1543721:AAY24_RS06185
uniprot id: A0A0F7JZC2
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1543721:AAY24 RS05430
gene id: 1543721:AAY24_RS05430
uniprot id: A0A0F7JYY1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1543721:AAY24 RS14230
gene id: 1543721:AAY24_RS14230
uniprot id: A0A0F7K324
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1543721:AAY24 RS00345
gene id: 1543721:AAY24_RS00345
uniprot id: A0A0F7JWT9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

1543721:AAY24 RS12290
gene id: 1543721:AAY24_RS12290
uniprot id: A0A0F7K064
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1543721:AAY24 RS01465
gene id: 1543721:AAY24_RS01465
uniprot id: A0A0F7JV75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1543721:AAY24 RS12280
gene id: 1543721:AAY24_RS12280
uniprot id: A0A0F7K239
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1543721:AAY24 RS06875
gene id: 1543721:AAY24_RS06875
uniprot id: A0A0F7JU95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1543721:AAY24 RS12735
gene id: 1543721:AAY24_RS12735
uniprot id: A0A0F7K1N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1543721:AAY24 RS15015
gene id: 1543721:AAY24_RS15015
uniprot id: A0A0F7K3D1
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1543721:AAY24 RS06565
gene id: 1543721:AAY24_RS06565
uniprot id: A0A0F7JWU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1543721:AAY24 RS15020
gene id: 1543721:AAY24_RS15020
uniprot id: A0A0F7K1J2
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1543721:AAY24 RS05370
gene id: 1543721:AAY24_RS05370
uniprot id: A0A0F7JYX9
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1543721:AAY24 RS17030
gene id: 1543721:AAY24_RS17030
uniprot id: A0A0F7K1K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1543721:AAY24 RS14600
gene id: 1543721:AAY24_RS14600
uniprot id: A0A0F7K0H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1543721:AAY24 RS14525
gene id: 1543721:AAY24_RS14525
uniprot id: A0A0F7K1C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1543721:AAY24 RS03950
gene id: 1543721:AAY24_RS03950
uniprot id: A0A0F7JT62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1543721:AAY24 RS09425
gene id: 1543721:AAY24_RS09425
uniprot id: A0A0F7JXV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1543721:AAY24 RS17175
gene id: 1543721:AAY24_RS17175
uniprot id: A0A0F7K3H1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS01960
gene id: 1543721:AAY24_RS01960
uniprot id: A0A0F7JVG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1543721:AAY24 RS13550
gene id: 1543721:AAY24_RS13550
uniprot id: A0A0F7K2R6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1543721:AAY24 RS11405
gene id: 1543721:AAY24_RS11405
uniprot id: A0A0F7JWJ7
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS05760
gene id: 1543721:AAY24_RS05760
uniprot id: A0A0F7JZ14
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS11925
gene id: 1543721:AAY24_RS11925
uniprot id: A0A0F7K1X2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1543721:AAY24 RS07495
gene id: 1543721:AAY24_RS07495
uniprot id: A0A0F7JZZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1543721:AAY24 RS07080
gene id: 1543721:AAY24_RS07080
uniprot id: A0A0F7JZX0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS04440
gene id: 1543721:AAY24_RS04440
uniprot id: A0A0F7JY12
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1543721:AAY24 RS05555
gene id: 1543721:AAY24_RS05555
uniprot id: A0A0F7JYF0
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS07245
gene id: 1543721:AAY24_RS07245
uniprot id: A0A0F7JUF6
names: Similarity
messages: Belongs to the MotB family.

1543721:AAY24 RS03240
gene id: 1543721:AAY24_RS03240
uniprot id: A0A0F7JVW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1543721:AAY24 RS15010
gene id: 1543721:AAY24_RS15010
uniprot id: A0A0F7K0N2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1543721:AAY24 RS14530
gene id: 1543721:AAY24_RS14530
uniprot id: A0A0F7K2D8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1543721:AAY24 RS13415
gene id: 1543721:AAY24_RS13415
uniprot id: A0A0F7K2N9
names: Similarity
messages: Belongs to the UPF0751 family.

1543721:AAY24 RS02345
gene id: 1543721:AAY24_RS02345
uniprot id: A0A0F7JXN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1543721:AAY24 RS08250
gene id: 1543721:AAY24_RS08250
uniprot id: A0A0F7JZG5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1543721:AAY24 RS08375
gene id: 1543721:AAY24_RS08375
uniprot id: A0A0F7JYK9
names: Similarity
messages: Belongs to the universal stress protein A family.

1543721:AAY24 RS12815
gene id: 1543721:AAY24_RS12815
uniprot id: A0A0F7K2F5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1543721:AAY24 RS13955
gene id: 1543721:AAY24_RS13955
uniprot id: A0A0F7K125
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1543721:AAY24 RS03910
gene id: 1543721:AAY24_RS03910
uniprot id: A0A0F7JXX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1543721:AAY24 RS13000
gene id: 1543721:AAY24_RS13000
uniprot id: A0A0F7JZP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1543721:AAY24 RS04445
gene id: 1543721:AAY24_RS04445
uniprot id: A0A0F7JTB2
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1543721:AAY24 RS17010
gene id: 1543721:AAY24_RS17010
uniprot id: A0A0F7K3F5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1543721:AAY24 RS00235
gene id: 1543721:AAY24_RS00235
uniprot id: A0A0F7JWT2
names: Similarity
messages: Belongs to the HypE family.

1543721:AAY24 RS05885
gene id: 1543721:AAY24_RS05885
uniprot id: A0A0F7JTT7
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1543721:AAY24 RS14840
gene id: 1543721:AAY24_RS14840
uniprot id: A0A0F7K0L2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1543721:AAY24 RS11450
gene id: 1543721:AAY24_RS11450
uniprot id: A0A0F7K110
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1543721:AAY24 RS07770
gene id: 1543721:AAY24_RS07770
uniprot id: A0A0F7JXA4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1543721:AAY24 RS06130
gene id: 1543721:AAY24_RS06130
uniprot id: A0A0F7JWE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1543721:AAY24 RS04670
gene id: 1543721:AAY24_RS04670
uniprot id: A0A0F7JYP0
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1543721:AAY24 RS14085
gene id: 1543721:AAY24_RS14085
uniprot id: A0A0F7K0C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1543721:AAY24 RS16355
gene id: 1543721:AAY24_RS16355
uniprot id: A0A0F7K1A4
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS01835
gene id: 1543721:AAY24_RS01835
uniprot id: A0A0F7JS56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1543721:AAY24 RS05375
gene id: 1543721:AAY24_RS05375
uniprot id: A0A0F7JWW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1543721:AAY24 RS02550
gene id: 1543721:AAY24_RS02550
uniprot id: A0A0F7JSE0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1543721:AAY24 RS16215
gene id: 1543721:AAY24_RS16215
uniprot id: A0A0F7K515
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1543721:AAY24 RS09805
gene id: 1543721:AAY24_RS09805
uniprot id: A0A0F7JVS9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1543721:AAY24 RS10205
gene id: 1543721:AAY24_RS10205
uniprot id: A0A0F7JZD1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1543721:AAY24 RS17140
gene id: 1543721:AAY24_RS17140
uniprot id: A0A0F7K2J3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1543721:AAY24 RS01565
gene id: 1543721:AAY24_RS01565
uniprot id: A0A0F7JRZ3
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1543721:AAY24 RS09900
gene id: 1543721:AAY24_RS09900
uniprot id: A0A0F7JY56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1543721:AAY24 RS12655
gene id: 1543721:AAY24_RS12655
uniprot id: A0A0F7JZH5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1543721:AAY24 RS00975
gene id: 1543721:AAY24_RS00975
uniprot id: A0A0F7JV06
names: Similarity
messages: Belongs to the CFA/CMAS family.

1543721:AAY24 RS10280
gene id: 1543721:AAY24_RS10280
uniprot id: A0A0F7K0K0
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1543721:AAY24 RS13995
gene id: 1543721:AAY24_RS13995
uniprot id: A0A0F7K094
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1543721:AAY24 RS04045
gene id: 1543721:AAY24_RS04045
uniprot id: A0A0F7JT88
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1543721:AAY24 RS17385
gene id: 1543721:AAY24_RS17385
uniprot id: A0A0F7K3J3
names: Similarity
messages: Belongs to the HSP15 family.

1543721:AAY24 RS16955
gene id: 1543721:AAY24_RS16955
uniprot id: A0A0F7K3E6
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1543721:AAY24 RS13730
gene id: 1543721:AAY24_RS13730
uniprot id: A0A0F7K2U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1543721:AAY24 RS07460
gene id: 1543721:AAY24_RS07460
uniprot id: A0A0F7JZA7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1543721:AAY24 RS15235
gene id: 1543721:AAY24_RS15235
uniprot id: A0A0F7JYQ8
names: Subcellular Location Annotation
messages: Membrane

1543721:AAY24 RS17730
gene id: 1543721:AAY24_RS17730
uniprot id: A0A0F7K4G7
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1543721:AAY24 RS02970
gene id: 1543721:AAY24_RS02970
uniprot id: A0A0F7JSQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1543721:AAY24 RS07075
gene id: 1543721:AAY24_RS07075
uniprot id: A0A0F7JX20
names: Similarity
messages: Belongs to the gamma-class carbonic anhydrase family.

1543721:AAY24 RS16510
gene id: 1543721:AAY24_RS16510
uniprot id: A0A0F7JZH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1543721:AAY24 RS07400
gene id: 1543721:AAY24_RS07400
uniprot id: A0A0F7JUI2
names: Caution
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1543721:AAY24 RS14065
gene id: 1543721:AAY24_RS14065
uniprot id: A0A0F7K2Z6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1543721:AAY24 RS14725
gene id: 1543721:AAY24_RS14725
uniprot id: A0A0F7K2G4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1543721:AAY24 RS03785
gene id: 1543721:AAY24_RS03785
uniprot id: A0A0F7JXW4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1543721:AAY24 RS12720
gene id: 1543721:AAY24_RS12720
uniprot id: A0A0F7JZJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1543721:AAY24 RS09800
gene id: 1543721:AAY24_RS09800
uniprot id: A0A0F7K0B5
names: Similarity
messages: Belongs to the GSP E family.

1543721:AAY24 RS09755
gene id: 1543721:AAY24_RS09755
uniprot id: A0A0F7K0V2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.