1538553:JT25 RS14280
gene id: 1538553:JT25_RS14280
uniprot id: A0A126T6B9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1538553:JT25 RS17385
gene id: 1538553:JT25_RS17385
uniprot id: A0A126T818
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS14625
gene id: 1538553:JT25_RS14625
uniprot id: A0A126T6K1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1538553:JT25 RS09350
gene id: 1538553:JT25_RS09350
uniprot id: A0A126T3M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS15330
gene id: 1538553:JT25_RS15330
uniprot id: A0A126T721
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1538553:JT25 RS08060
gene id: 1538553:JT25_RS08060
uniprot id: A0A126T2Z4
names: Similarity
messages: Belongs to the citrate synthase family.

1538553:JT25 RS14790
gene id: 1538553:JT25_RS14790
uniprot id: A0A126T6L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1538553:JT25 RS02370
gene id: 1538553:JT25_RS02370
uniprot id: A0A140E4L9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1538553:JT25 RS06585
gene id: 1538553:JT25_RS06585
uniprot id: A0A126T250
names: Similarity
messages: Belongs to the HupF/HypC family.

1538553:JT25 RS17875
gene id: 1538553:JT25_RS17875
uniprot id: A0A126T8B5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1538553:JT25 RS17815
gene id: 1538553:JT25_RS17815
uniprot id: A0A126T8C7
names: Similarity
messages: Belongs to the hemerythrin family.

1538553:JT25 RS20720
gene id: 1538553:JT25_RS20720
uniprot id: A0A140E654
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1538553:JT25 RS11005
gene id: 1538553:JT25_RS11005
uniprot id: A0A126T4I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1538553:JT25 RS02770
gene id: 1538553:JT25_RS02770
uniprot id: A0A140E4U7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS03550
gene id: 1538553:JT25_RS03550
uniprot id: A0A140E595
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1538553:JT25 RS17595
gene id: 1538553:JT25_RS17595
uniprot id: A0A126T869
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1538553:JT25 RS13930
gene id: 1538553:JT25_RS13930
uniprot id: A0A126T682
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1538553:JT25 RS18070
gene id: 1538553:JT25_RS18070
uniprot id: A0A126T8I5
names: Similarity
messages: Belongs to the asparagine synthetase family.

1538553:JT25 RS04815
gene id: 1538553:JT25_RS04815
uniprot id: A0A126T155
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

1538553:JT25 RS16905
gene id: 1538553:JT25_RS16905
uniprot id: A0A126T7U1
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1538553:JT25 RS13915
gene id: 1538553:JT25_RS13915
uniprot id: A0A126T666
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1538553:JT25 RS15220
gene id: 1538553:JT25_RS15220
uniprot id: A0A126T6V8
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS12970
gene id: 1538553:JT25_RS12970
uniprot id: A0A126T5P4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1538553:JT25 RS09160
gene id: 1538553:JT25_RS09160
uniprot id: A0A126T3J6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1538553:JT25 RS14275
gene id: 1538553:JT25_RS14275
uniprot id: A0A126T6G5
names: Similarity
messages: Belongs to the PhoH family.

1538553:JT25 RS19780
gene id: 1538553:JT25_RS19780
uniprot id: A0A140E5M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS01300
gene id: 1538553:JT25_RS01300
uniprot id: A0A140E407
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1538553:JT25 RS19250
gene id: 1538553:JT25_RS19250
uniprot id: A0A126T926
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1538553:JT25 RS10060
gene id: 1538553:JT25_RS10060
uniprot id: A0A126T421
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1538553:JT25 RS07520
gene id: 1538553:JT25_RS07520
uniprot id: A0A126T2N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1538553:JT25 RS07970
gene id: 1538553:JT25_RS07970
uniprot id: A0A126T2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1538553:JT25 RS22165
gene id: 1538553:JT25_RS22165
uniprot id: A0A140E6Y0
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1538553:JT25 RS16780
gene id: 1538553:JT25_RS16780
uniprot id: A0A126T7R8
names: Similarity
messages: Belongs to the YoeB family.

1538553:JT25 RS11545
gene id: 1538553:JT25_RS11545
uniprot id: A0A126T4U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1538553:JT25 RS11265
gene id: 1538553:JT25_RS11265
uniprot id: A0A126T4S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1538553:JT25 RS12975
gene id: 1538553:JT25_RS12975
uniprot id: A0A126T5L3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1538553:JT25 RS14705
gene id: 1538553:JT25_RS14705
uniprot id: A0A126T6N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1538553:JT25 RS06185
gene id: 1538553:JT25_RS06185
uniprot id: A0A126T1X5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1538553:JT25 RS03180
gene id: 1538553:JT25_RS03180
uniprot id: A0A140E526
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1538553:JT25 RS12325
gene id: 1538553:JT25_RS12325
uniprot id: A0A126T5A7
names: Similarity
messages: Belongs to the peptidase S41A family.

1538553:JT25 RS04145
gene id: 1538553:JT25_RS04145
uniprot id: A0A126T0P0
names: Similarity
messages: Belongs to the CutA family.

1538553:JT25 RS23490
gene id: 1538553:JT25_RS23490
uniprot id: A0A140E7N9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1538553:JT25 RS00285
gene id: 1538553:JT25_RS00285
uniprot id: A0A140E3G2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1538553:JT25 RS06755
gene id: 1538553:JT25_RS06755
uniprot id: A0A126T278
names: Subcellular Location Annotation
messages: Cytoplasm

1538553:JT25 RS13785
gene id: 1538553:JT25_RS13785
uniprot id: A0A126T629
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1538553:JT25 RS13895
gene id: 1538553:JT25_RS13895
uniprot id: A0A126T649
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1538553:JT25 RS01625
gene id: 1538553:JT25_RS01625
uniprot id: A0A140E471
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1538553:JT25 RS15955
gene id: 1538553:JT25_RS15955
uniprot id: A0A126T863
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1538553:JT25 RS22310
gene id: 1538553:JT25_RS22310
uniprot id: A0A140E708
names: Similarity
messages: Belongs to the PhzF family.

1538553:JT25 RS10350
gene id: 1538553:JT25_RS10350
uniprot id: A0A126T574
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1538553:JT25 RS07630
gene id: 1538553:JT25_RS07630
uniprot id: A0A126T2S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1538553:JT25 RS21560
gene id: 1538553:JT25_RS21560
uniprot id: A0A140E6L4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1538553:JT25 RS00270
gene id: 1538553:JT25_RS00270
uniprot id: A0A140E3F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1538553:JT25 RS12220
gene id: 1538553:JT25_RS12220
uniprot id: A0A126T588
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1538553:JT25 RS01380
gene id: 1538553:JT25_RS01380
uniprot id: A0A140E422
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS14235
gene id: 1538553:JT25_RS14235
uniprot id: A0A126T6B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1538553:JT25 RS11475
gene id: 1538553:JT25_RS11475
uniprot id: A0A126T4U8
names: Similarity
messages: Belongs to the NifX/NifY family.

1538553:JT25 RS04980
gene id: 1538553:JT25_RS04980
uniprot id: A0A126T185
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1538553:JT25 RS18710
gene id: 1538553:JT25_RS18710
uniprot id: A0A126T8U2
names: Similarity
messages: Belongs to the hemerythrin family.

1538553:JT25 RS13380
gene id: 1538553:JT25_RS13380
uniprot id: A0A126T5X0
names: Similarity
messages: Belongs to the ArsC family.

1538553:JT25 RS18715
gene id: 1538553:JT25_RS18715
uniprot id: A0A126T8Y8
names: Similarity
messages: Belongs to the hemerythrin family.

1538553:JT25 RS09545
gene id: 1538553:JT25_RS09545
uniprot id: A0A126T3U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1538553:JT25 RS17360
gene id: 1538553:JT25_RS17360
uniprot id: A0A126T858
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1538553:JT25 RS15935
gene id: 1538553:JT25_RS15935
uniprot id: A0A126T7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1538553:JT25 RS06775
gene id: 1538553:JT25_RS06775
uniprot id: A0A126T2A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS14750
gene id: 1538553:JT25_RS14750
uniprot id: A0A126T6J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1538553:JT25 RS13925
gene id: 1538553:JT25_RS13925
uniprot id: A0A126T660
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1538553:JT25 RS13355
gene id: 1538553:JT25_RS13355
uniprot id: A0A126T5V6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1538553:JT25 RS17585
gene id: 1538553:JT25_RS17585
uniprot id: A0A126T857
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS02320
gene id: 1538553:JT25_RS02320
uniprot id: A0A140E4K9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1538553:JT25 RS06690
gene id: 1538553:JT25_RS06690
uniprot id: A0A126T268
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.

1538553:JT25 RS18645
gene id: 1538553:JT25_RS18645
uniprot id: A0A126T9K8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1538553:JT25 RS22420
gene id: 1538553:JT25_RS22420
uniprot id: A0A140E730
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1538553:JT25 RS18465
gene id: 1538553:JT25_RS18465
uniprot id: A0A126T8R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS12550
gene id: 1538553:JT25_RS12550
uniprot id: A0A126T5E8
names: Similarity
messages: Belongs to the VgrG protein family.

1538553:JT25 RS14820
gene id: 1538553:JT25_RS14820
uniprot id: A0A126T6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1538553:JT25 RS10445
gene id: 1538553:JT25_RS10445
uniprot id: A0A126T4B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1538553:JT25 RS03315
gene id: 1538553:JT25_RS03315
uniprot id: A0A140E553
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS10200
gene id: 1538553:JT25_RS10200
uniprot id: A0A126T448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
messages: Membrane

1538553:JT25 RS08150
gene id: 1538553:JT25_RS08150
uniprot id: A0A126T2Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1538553:JT25 RS05070
gene id: 1538553:JT25_RS05070
uniprot id: A0A126T1A6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1538553:JT25 RS07295
gene id: 1538553:JT25_RS07295
uniprot id: A0A126T2K0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1538553:JT25 RS17555
gene id: 1538553:JT25_RS17555
uniprot id: A0A126T851
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1538553:JT25 RS04115
gene id: 1538553:JT25_RS04115
uniprot id: A0A126T1V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1538553:JT25 RS16340
gene id: 1538553:JT25_RS16340
uniprot id: A0A126T7J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

1538553:JT25 RS18140
gene id: 1538553:JT25_RS18140
uniprot id: A0A126T8I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1538553:JT25 RS16400
gene id: 1538553:JT25_RS16400
uniprot id: A0A126T7N1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1538553:JT25 RS01915
gene id: 1538553:JT25_RS01915
uniprot id: A0A140E4C8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1538553:JT25 RS03655
gene id: 1538553:JT25_RS03655
uniprot id: A0A140E5B6
names: Similarity
messages: Belongs to the peptidase A31 family.

1538553:JT25 RS20740
gene id: 1538553:JT25_RS20740
uniprot id: A0A140E658
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS06000
gene id: 1538553:JT25_RS06000
uniprot id: A0A126T1U7
names: Similarity
messages: Belongs to the ArsC family.

1538553:JT25 RS15155
gene id: 1538553:JT25_RS15155
uniprot id: A0A126T6W9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1538553:JT25 RS14830
gene id: 1538553:JT25_RS14830
uniprot id: A0A126T6M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1538553:JT25 RS12630
gene id: 1538553:JT25_RS12630
uniprot id: A0A126T5G4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS12725
gene id: 1538553:JT25_RS12725
uniprot id: A0A126T5G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1538553:JT25 RS15215
gene id: 1538553:JT25_RS15215
uniprot id: A0A126T702
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS21545
gene id: 1538553:JT25_RS21545
uniprot id: A0A140E6L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1538553:JT25 RS08030
gene id: 1538553:JT25_RS08030
uniprot id: A0A126T2Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1538553:JT25 RS17885
gene id: 1538553:JT25_RS17885
uniprot id: A0A126T8B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS12265
gene id: 1538553:JT25_RS12265
uniprot id: A0A126T593
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS05910
gene id: 1538553:JT25_RS05910
uniprot id: A0A126T1S0
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1538553:JT25 RS04030
gene id: 1538553:JT25_RS04030
uniprot id: A0A140E5I8
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1538553:JT25 RS09155
gene id: 1538553:JT25_RS09155
uniprot id: A0A126T4J6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1538553:JT25 RS15360
gene id: 1538553:JT25_RS15360
uniprot id: A0A126T6Z0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1538553:JT25 RS05915
gene id: 1538553:JT25_RS05915
uniprot id: A0A126T1S8
names: Similarity
messages: Belongs to the RNase T2 family.

1538553:JT25 RS04775
gene id: 1538553:JT25_RS04775
uniprot id: A0A126T142
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1538553:JT25 RS02860
gene id: 1538553:JT25_RS02860
uniprot id: A0A140E4W5
names: Function
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.

1538553:JT25 RS01725
gene id: 1538553:JT25_RS01725
uniprot id: A0A140E491
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1538553:JT25 RS15945
gene id: 1538553:JT25_RS15945
uniprot id: A0A126T7A6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1538553:JT25 RS11690
gene id: 1538553:JT25_RS11690
uniprot id: A0A126T4Y9
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS14785
gene id: 1538553:JT25_RS14785
uniprot id: A0A126T7J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1538553:JT25 RS00830
gene id: 1538553:JT25_RS00830
uniprot id: A0A140E3R6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1538553:JT25 RS00255
gene id: 1538553:JT25_RS00255
uniprot id: A0A140E3F6
names: Similarity
messages: Belongs to the DsrF/TusC family.

1538553:JT25 RS00510
gene id: 1538553:JT25_RS00510
uniprot id: A0A140E3K7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1538553:JT25 RS02220
gene id: 1538553:JT25_RS02220
uniprot id: A0A140E4I9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1538553:JT25 RS18800
gene id: 1538553:JT25_RS18800
uniprot id: A0A126T8U5
names: Subcellular Location Annotation
messages: Cytoplasm

1538553:JT25 RS08175
gene id: 1538553:JT25_RS08175
uniprot id: A0A126T330
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS17890
gene id: 1538553:JT25_RS17890
uniprot id: A0A126T8D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1538553:JT25 RS14305
gene id: 1538553:JT25_RS14305
uniprot id: A0A126T6E1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1538553:JT25 RS12000
gene id: 1538553:JT25_RS12000
uniprot id: A0A126T545
names: Similarity
messages: Belongs to the transposase 8 family.

1538553:JT25 RS06015
gene id: 1538553:JT25_RS06015
uniprot id: A0A126T1U8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS18240
gene id: 1538553:JT25_RS18240
uniprot id: A0A126T8K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1538553:JT25 RS08220
gene id: 1538553:JT25_RS08220
uniprot id: A0A126T328
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS16710
gene id: 1538553:JT25_RS16710
uniprot id: A0A126T7Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS14060
gene id: 1538553:JT25_RS14060
uniprot id: A0A126T689
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1538553:JT25 RS09175
gene id: 1538553:JT25_RS09175
uniprot id: A0A126T3K5
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1538553:JT25 RS22670
gene id: 1538553:JT25_RS22670
uniprot id: A0A140E780
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1538553:JT25 RS04095
gene id: 1538553:JT25_RS04095
uniprot id: A0A140E5J6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1538553:JT25 RS04415
gene id: 1538553:JT25_RS04415
uniprot id: A0A126T211
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1538553:JT25 RS15795
gene id: 1538553:JT25_RS15795
uniprot id: A0A126T772
names: Similarity
messages: Belongs to the peptidase S8 family.

1538553:JT25 RS01890
gene id: 1538553:JT25_RS01890
uniprot id: A0A140E4C3
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1538553:JT25 RS12780
gene id: 1538553:JT25_RS12780
uniprot id: A0A126T5J7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1538553:JT25 RS06085
gene id: 1538553:JT25_RS06085
uniprot id: A0A126T1V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1538553:JT25 RS14745
gene id: 1538553:JT25_RS14745
uniprot id: A0A126T6M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1538553:JT25 RS21315
gene id: 1538553:JT25_RS21315
uniprot id: A0A140E6G9
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1538553:JT25 RS22640
gene id: 1538553:JT25_RS22640
uniprot id: A0A140E774
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS13020
gene id: 1538553:JT25_RS13020
uniprot id: A0A126T5M8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1538553:JT25 RS13045
gene id: 1538553:JT25_RS13045
uniprot id: A0A126T6J6
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.

1538553:JT25 RS00475
gene id: 1538553:JT25_RS00475
uniprot id: A0A140E3K0
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1538553:JT25 RS01990
gene id: 1538553:JT25_RS01990
uniprot id: A0A140E4E3
names: Similarity
messages: Belongs to the P(II) protein family.

1538553:JT25 RS16815
gene id: 1538553:JT25_RS16815
uniprot id: A0A126T7Q1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS00280
gene id: 1538553:JT25_RS00280
uniprot id: A0A140E3G1
names: Similarity
messages: Belongs to the RutC family.

1538553:JT25 RS03030
gene id: 1538553:JT25_RS03030
uniprot id: A0A140E4Z8
names: Similarity
messages: Belongs to the PhzF family.

1538553:JT25 RS03055
gene id: 1538553:JT25_RS03055
uniprot id: A0A140E502
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1538553:JT25 RS02705
gene id: 1538553:JT25_RS02705
uniprot id: A0A140E4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS11510
gene id: 1538553:JT25_RS11510
uniprot id: A0A126T4V9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1538553:JT25 RS06805
gene id: 1538553:JT25_RS06805
uniprot id: A0A126T2A0
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

1538553:JT25 RS04350
gene id: 1538553:JT25_RS04350
uniprot id: A0A126T0V4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1538553:JT25 RS04170
gene id: 1538553:JT25_RS04170
uniprot id: A0A126T0S5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1538553:JT25 RS13005
gene id: 1538553:JT25_RS13005
uniprot id: A0A126T5N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1538553:JT25 RS12525
gene id: 1538553:JT25_RS12525
uniprot id: A0A126T5E5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1538553:JT25 RS15405
gene id: 1538553:JT25_RS15405
uniprot id: A0A126T6X9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1538553:JT25 RS12730
gene id: 1538553:JT25_RS12730
uniprot id: A0A126T5I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1538553:JT25 RS10850
gene id: 1538553:JT25_RS10850
uniprot id: A0A126T4J8
names: Similarity
messages: Belongs to the YciI family.

1538553:JT25 RS09320
gene id: 1538553:JT25_RS09320
uniprot id: A0A126T3P7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1538553:JT25 RS05275
gene id: 1538553:JT25_RS05275
uniprot id: A0A126T2G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1538553:JT25 RS14665
gene id: 1538553:JT25_RS14665
uniprot id: A0A126T6P0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS10015
gene id: 1538553:JT25_RS10015
uniprot id: A0A126T435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS17325
gene id: 1538553:JT25_RS17325
uniprot id: A0A126T809
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

1538553:JT25 RS17155
gene id: 1538553:JT25_RS17155
uniprot id: A0A126T7Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1538553:JT25 RS08215
gene id: 1538553:JT25_RS08215
uniprot id: A0A126T315
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1538553:JT25 RS07745
gene id: 1538553:JT25_RS07745
uniprot id: A0A126T2T6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1538553:JT25 RS15970
gene id: 1538553:JT25_RS15970
uniprot id: A0A126T799
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1538553:JT25 RS16045
gene id: 1538553:JT25_RS16045
uniprot id: A0A126T7C4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS06305
gene id: 1538553:JT25_RS06305
uniprot id: A0A126T3Y9
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1538553:JT25 RS09855
gene id: 1538553:JT25_RS09855
uniprot id: A0A126T403
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1538553:JT25 RS17225
gene id: 1538553:JT25_RS17225
uniprot id: A0A126T7Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1538553:JT25 RS12720
gene id: 1538553:JT25_RS12720
uniprot id: A0A126T5J5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1538553:JT25 RS19635
gene id: 1538553:JT25_RS19635
uniprot id: A0A140E5J9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1538553:JT25 RS00490
gene id: 1538553:JT25_RS00490
uniprot id: A0A140E6H2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1538553:JT25 RS09485
gene id: 1538553:JT25_RS09485
uniprot id: A0A126T3S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS21305
gene id: 1538553:JT25_RS21305
uniprot id: A0A140E6G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS19785
gene id: 1538553:JT25_RS19785
uniprot id: A0A140E5M9
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1538553:JT25 RS07125
gene id: 1538553:JT25_RS07125
uniprot id: A0A126T2G5
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS19975
gene id: 1538553:JT25_RS19975
uniprot id: A0A140E5R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1538553:JT25 RS07615
gene id: 1538553:JT25_RS07615
uniprot id: A0A126T2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1538553:JT25 RS10965
gene id: 1538553:JT25_RS10965
uniprot id: A0A126T4I7
names: Similarity
messages: Belongs to the peptidase S16 family.

1538553:JT25 RS12045
gene id: 1538553:JT25_RS12045
uniprot id: A0A126T553
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1538553:JT25 RS15385
gene id: 1538553:JT25_RS15385
uniprot id: A0A126T6Y6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1538553:JT25 RS06615
gene id: 1538553:JT25_RS06615
uniprot id: A0A126T255
names: Similarity
messages: Belongs to the HupH/HyaF family.

1538553:JT25 RS01920
gene id: 1538553:JT25_RS01920
uniprot id: A0A140E4C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1538553:JT25 RS06460
gene id: 1538553:JT25_RS06460
uniprot id: A0A126T224
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1538553:JT25 RS06385
gene id: 1538553:JT25_RS06385
uniprot id: A0A126T215
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1538553:JT25 RS09845
gene id: 1538553:JT25_RS09845
uniprot id: A0A126T3Z2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1538553:JT25 RS05540
gene id: 1538553:JT25_RS05540
uniprot id: A0A126T1K1
names: Subcellular Location Annotation
messages: Cell inner membrane

1538553:JT25 RS03420
gene id: 1538553:JT25_RS03420
uniprot id: A0A140E569
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1538553:JT25 RS04705
gene id: 1538553:JT25_RS04705
uniprot id: A0A126T134
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1538553:JT25 RS20075
gene id: 1538553:JT25_RS20075
uniprot id: A0A140E5T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS23120
gene id: 1538553:JT25_RS23120
uniprot id: A0A140E7G8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1538553:JT25 RS22740
gene id: 1538553:JT25_RS22740
uniprot id: A0A140E794
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1538553:JT25 RS06500
gene id: 1538553:JT25_RS06500
uniprot id: A0A126T237
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1538553:JT25 RS20770
gene id: 1538553:JT25_RS20770
uniprot id: A0A140E664
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1538553:JT25 RS21285
gene id: 1538553:JT25_RS21285
uniprot id: A0A140E6G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1538553:JT25 RS09925
gene id: 1538553:JT25_RS09925
uniprot id: A0A126T419
names: Similarity
messages: Belongs to the TrpC family.

1538553:JT25 RS07290
gene id: 1538553:JT25_RS07290
uniprot id: A0A126T2H5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1538553:JT25 RS06930
gene id: 1538553:JT25_RS06930
uniprot id: A0A126T2B3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1538553:JT25 RS23170
gene id: 1538553:JT25_RS23170
uniprot id: A0A140E7H7
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS04085
gene id: 1538553:JT25_RS04085
uniprot id: A0A140E5J4
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1538553:JT25 RS02115
gene id: 1538553:JT25_RS02115
uniprot id: A0A140E4G8
names: Subcellular Location Annotation
messages: Cell inner membrane

1538553:JT25 RS00390
gene id: 1538553:JT25_RS00390
uniprot id: A0A140E3I3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1538553:JT25 RS15025
gene id: 1538553:JT25_RS15025
uniprot id: A0A126T6R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1538553:JT25 RS11790
gene id: 1538553:JT25_RS11790
uniprot id: A0A126T508
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1538553:JT25 RS00985
gene id: 1538553:JT25_RS00985
uniprot id: A0A140E3U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1538553:JT25 RS16235
gene id: 1538553:JT25_RS16235
uniprot id: A0A126T7E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

1538553:JT25 RS02335
gene id: 1538553:JT25_RS02335
uniprot id: A0A140E4L2
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS18610
gene id: 1538553:JT25_RS18610
uniprot id: A0A126T8R7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1538553:JT25 RS17160
gene id: 1538553:JT25_RS17160
uniprot id: A0A126T7Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1538553:JT25 RS06150
gene id: 1538553:JT25_RS06150
uniprot id: A0A126T1X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1538553:JT25 RS18840
gene id: 1538553:JT25_RS18840
uniprot id: A0A126T8Y2
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1538553:JT25 RS08615
gene id: 1538553:JT25_RS08615
uniprot id: A0A126T3A1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1538553:JT25 RS00150
gene id: 1538553:JT25_RS00150
uniprot id: A0A140E3D5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1538553:JT25 RS05065
gene id: 1538553:JT25_RS05065
uniprot id: A0A126T1A0
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1538553:JT25 RS18975
gene id: 1538553:JT25_RS18975
uniprot id: A0A126T946
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS09625
gene id: 1538553:JT25_RS09625
uniprot id: A0A126T3V7
names: Similarity
messages: Belongs to the nitroreductase family.

1538553:JT25 RS08790
gene id: 1538553:JT25_RS08790
uniprot id: A0A126T4B1
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1538553:JT25 RS15505
gene id: 1538553:JT25_RS15505
uniprot id: A0A126T6Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1538553:JT25 RS08920
gene id: 1538553:JT25_RS08920
uniprot id: A0A140E7P8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS18960
gene id: 1538553:JT25_RS18960
uniprot id: A0A126T8Y3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

1538553:JT25 RS03500
gene id: 1538553:JT25_RS03500
uniprot id: A0A140E585
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS15485
gene id: 1538553:JT25_RS15485
uniprot id: A0A126T706
names: Similarity
messages: Belongs to the MlaA family.

1538553:JT25 RS04235
gene id: 1538553:JT25_RS04235
uniprot id: A0A126T0T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS01590
gene id: 1538553:JT25_RS01590
uniprot id: A0A140E464
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1538553:JT25 RS19710
gene id: 1538553:JT25_RS19710
uniprot id: A0A140E5L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1538553:JT25 RS12825
gene id: 1538553:JT25_RS12825
uniprot id: A0A126T5I2
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS21070
gene id: 1538553:JT25_RS21070
uniprot id: A0A140E6C2
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1538553:JT25 RS16460
gene id: 1538553:JT25_RS16460
uniprot id: A0A126T7K4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1538553:JT25 RS06610
gene id: 1538553:JT25_RS06610
uniprot id: A0A126T364
names: Similarity
messages: Belongs to the rubredoxin family.

1538553:JT25 RS22695
gene id: 1538553:JT25_RS22695
uniprot id: A0A140E785
names: PTM
messages: Binds 1 heme group per subunit.

1538553:JT25 RS18640
gene id: 1538553:JT25_RS18640
uniprot id: A0A126T8R5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS12655
gene id: 1538553:JT25_RS12655
uniprot id: A0A126T5G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

1538553:JT25 RS04950
gene id: 1538553:JT25_RS04950
uniprot id: A0A126T173
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1538553:JT25 RS20585
gene id: 1538553:JT25_RS20585
uniprot id: A0A140E627
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1538553:JT25 RS07075
gene id: 1538553:JT25_RS07075
uniprot id: A0A126T2F8
names: Subcellular Location Annotation
messages: Cell inner membrane

1538553:JT25 RS16885
gene id: 1538553:JT25_RS16885
uniprot id: A0A126T7S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1538553:JT25 RS21290
gene id: 1538553:JT25_RS21290
uniprot id: A0A140E6G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1538553:JT25 RS03545
gene id: 1538553:JT25_RS03545
uniprot id: A0A140E594
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1538553:JT25 RS05280
gene id: 1538553:JT25_RS05280
uniprot id: A0A126T1E8
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS18665
gene id: 1538553:JT25_RS18665
uniprot id: A0A126T8X8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1538553:JT25 RS02700
gene id: 1538553:JT25_RS02700
uniprot id: A0A140E4T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1538553:JT25 RS03475
gene id: 1538553:JT25_RS03475
uniprot id: A0A140E580
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS12845
gene id: 1538553:JT25_RS12845
uniprot id: A0A126T5J6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1538553:JT25 RS09500
gene id: 1538553:JT25_RS09500
uniprot id: A0A126T3R3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1538553:JT25 RS07155
gene id: 1538553:JT25_RS07155
uniprot id: A0A126T2F5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1538553:JT25 RS11655
gene id: 1538553:JT25_RS11655
uniprot id: A0A126T4W4
names: Similarity
messages: Belongs to the LOG family.

1538553:JT25 RS07845
gene id: 1538553:JT25_RS07845
uniprot id: A0A126T3S7
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS08225
gene id: 1538553:JT25_RS08225
uniprot id: A0A126T336
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS17015
gene id: 1538553:JT25_RS17015
uniprot id: A0A126T7U4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1538553:JT25 RS05935
gene id: 1538553:JT25_RS05935
uniprot id: A0A126T1S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1538553:JT25 RS06900
gene id: 1538553:JT25_RS06900
uniprot id: A0A126T2B4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1538553:JT25 RS14600
gene id: 1538553:JT25_RS14600
uniprot id: A0A126T6I5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1538553:JT25 RS04360
gene id: 1538553:JT25_RS04360
uniprot id: A0A126T0W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1538553:JT25 RS03960
gene id: 1538553:JT25_RS03960
uniprot id: A0A140E5H4
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1538553:JT25 RS02080
gene id: 1538553:JT25_RS02080
uniprot id: A0A140E4G1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1538553:JT25 RS05315
gene id: 1538553:JT25_RS05315
uniprot id: A0A126T1E6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1538553:JT25 RS04385
gene id: 1538553:JT25_RS04385
uniprot id: A0A126T0W7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1538553:JT25 RS00405
gene id: 1538553:JT25_RS00405
uniprot id: A0A140E3I6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1538553:JT25 RS02270
gene id: 1538553:JT25_RS02270
uniprot id: A0A140E4J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1538553:JT25 RS07815
gene id: 1538553:JT25_RS07815
uniprot id: A0A126T2T3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1538553:JT25 RS18245
gene id: 1538553:JT25_RS18245
uniprot id: A0A126T8K0
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1538553:JT25 RS12860
gene id: 1538553:JT25_RS12860
uniprot id: A0A126T5L0
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1538553:JT25 RS16330
gene id: 1538553:JT25_RS16330
uniprot id: A0A126T7H6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1538553:JT25 RS12610
gene id: 1538553:JT25_RS12610
uniprot id: A0A126T5G1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1538553:JT25 RS07230
gene id: 1538553:JT25_RS07230
uniprot id: A0A126T2H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1538553:JT25 RS19450
gene id: 1538553:JT25_RS19450
uniprot id: A0A126T977
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1538553:JT25 RS12215
gene id: 1538553:JT25_RS12215
uniprot id: A0A126T583
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1538553:JT25 RS05325
gene id: 1538553:JT25_RS05325
uniprot id: A0A126T2H0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1538553:JT25 RS05460
gene id: 1538553:JT25_RS05460
uniprot id: A0A126T1H9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1538553:JT25 RS15420
gene id: 1538553:JT25_RS15420
uniprot id: A0A126T720
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1538553:JT25 RS04680
gene id: 1538553:JT25_RS04680
uniprot id: A0A126T133
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS22350
gene id: 1538553:JT25_RS22350
uniprot id: A0A140E716
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS13710
gene id: 1538553:JT25_RS13710
uniprot id: A0A126T638
names: Similarity
messages: Belongs to the UPF0234 family.

1538553:JT25 RS02215
gene id: 1538553:JT25_RS02215
uniprot id: A0A140E4I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1538553:JT25 RS03150
gene id: 1538553:JT25_RS03150
uniprot id: A0A140E521
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1538553:JT25 RS17995
gene id: 1538553:JT25_RS17995
uniprot id: A0A126T8F1
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1538553:JT25 RS12865
gene id: 1538553:JT25_RS12865
uniprot id: A0A126T5J9
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1538553:JT25 RS21945
gene id: 1538553:JT25_RS21945
uniprot id: A0A140E6T7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1538553:JT25 RS16795
gene id: 1538553:JT25_RS16795
uniprot id: A0A126T7Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1538553:JT25 RS08600
gene id: 1538553:JT25_RS08600
uniprot id: A0A126T395
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS01240
gene id: 1538553:JT25_RS01240
uniprot id: A0A140E3Z5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1538553:JT25 RS15555
gene id: 1538553:JT25_RS15555
uniprot id: A0A126T708
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1538553:JT25 RS12245
gene id: 1538553:JT25_RS12245
uniprot id: A0A126T595
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1538553:JT25 RS08405
gene id: 1538553:JT25_RS08405
uniprot id: A0A126T356
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1538553:JT25 RS20810
gene id: 1538553:JT25_RS20810
uniprot id: A0A140E672
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1538553:JT25 RS17400
gene id: 1538553:JT25_RS17400
uniprot id: A0A126T861
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1538553:JT25 RS17445
gene id: 1538553:JT25_RS17445
uniprot id: A0A126T839
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1538553:JT25 RS17510
gene id: 1538553:JT25_RS17510
uniprot id: A0A126T887
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1538553:JT25 RS18650
gene id: 1538553:JT25_RS18650
uniprot id: A0A126T8S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1538553:JT25 RS16910
gene id: 1538553:JT25_RS16910
uniprot id: A0A126T7U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1538553:JT25 RS22070
gene id: 1538553:JT25_RS22070
uniprot id: A0A140E6W1
names: Similarity
messages: Belongs to the transposase 7 family.

1538553:JT25 RS08200
gene id: 1538553:JT25_RS08200
uniprot id: A0A126T308
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1538553:JT25 RS20765
gene id: 1538553:JT25_RS20765
uniprot id: A0A140E663
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

1538553:JT25 RS13195
gene id: 1538553:JT25_RS13195
uniprot id: A0A126T6M6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS07410
gene id: 1538553:JT25_RS07410
uniprot id: A0A126T2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1538553:JT25 RS04265
gene id: 1538553:JT25_RS04265
uniprot id: A0A126T1Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1538553:JT25 RS09410
gene id: 1538553:JT25_RS09410
uniprot id: A0A126T3N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1538553:JT25 RS22275
gene id: 1538553:JT25_RS22275
uniprot id: A0A140E701
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1538553:JT25 RS06160
gene id: 1538553:JT25_RS06160
uniprot id: A0A126T1W9
names: Similarity
messages: Belongs to the elongation factor P family.

1538553:JT25 RS12010
gene id: 1538553:JT25_RS12010
uniprot id: A0A126T571
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1538553:JT25 RS06555
gene id: 1538553:JT25_RS06555
uniprot id: A0A126T247
names: Similarity
messages: Belongs to the YoeB family.

1538553:JT25 RS12785
gene id: 1538553:JT25_RS12785
uniprot id: A0A126T5I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1538553:JT25 RS03210
gene id: 1538553:JT25_RS03210
uniprot id: A0A140E532
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS09960
gene id: 1538553:JT25_RS09960
uniprot id: A0A126T404
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1538553:JT25 RS13610
gene id: 1538553:JT25_RS13610
uniprot id: A0A126T616
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1538553:JT25 RS18170
gene id: 1538553:JT25_RS18170
uniprot id: A0A126T8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS17390
gene id: 1538553:JT25_RS17390
uniprot id: A0A126T832
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1538553:JT25 RS00360
gene id: 1538553:JT25_RS00360
uniprot id: A0A140E3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS20705
gene id: 1538553:JT25_RS20705
uniprot id: A0A140E651
names: Similarity
messages: Belongs to the TrpF family.

1538553:JT25 RS05790
gene id: 1538553:JT25_RS05790
uniprot id: A0A126T1P4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS22395
gene id: 1538553:JT25_RS22395
uniprot id: A0A140E725
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1538553:JT25 RS02415
gene id: 1538553:JT25_RS02415
uniprot id: A0A140E4M8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1538553:JT25 RS10970
gene id: 1538553:JT25_RS10970
uniprot id: A0A126T5I5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1538553:JT25 RS12935
gene id: 1538553:JT25_RS12935
uniprot id: A0A126T5L2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1538553:JT25 RS14590
gene id: 1538553:JT25_RS14590
uniprot id: A0A126T6N3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1538553:JT25 RS17450
gene id: 1538553:JT25_RS17450
uniprot id: A0A126T874
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1538553:JT25 RS21215
gene id: 1538553:JT25_RS21215
uniprot id: A0A140E6E9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1538553:JT25 RS23355
gene id: 1538553:JT25_RS23355
uniprot id: A0A140E7L3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1538553:JT25 RS22360
gene id: 1538553:JT25_RS22360
uniprot id: A0A140E718
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS15045
gene id: 1538553:JT25_RS15045
uniprot id: A0A126T6S9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1538553:JT25 RS09360
gene id: 1538553:JT25_RS09360
uniprot id: A0A126T3N1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1538553:JT25 RS20495
gene id: 1538553:JT25_RS20495
uniprot id: A0A140E615
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS17145
gene id: 1538553:JT25_RS17145
uniprot id: A0A126T7X0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1538553:JT25 RS16175
gene id: 1538553:JT25_RS16175
uniprot id: A0A126T7G8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1538553:JT25 RS02380
gene id: 1538553:JT25_RS02380
uniprot id: A0A140E4M1
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1538553:JT25 RS21110
gene id: 1538553:JT25_RS21110
uniprot id: A0A140E6C9
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

1538553:JT25 RS13530
gene id: 1538553:JT25_RS13530
uniprot id: A0A126T5Z9
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS22415
gene id: 1538553:JT25_RS22415
uniprot id: A0A140E729
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1538553:JT25 RS03520
gene id: 1538553:JT25_RS03520
uniprot id: A0A140E589
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1538553:JT25 RS02160
gene id: 1538553:JT25_RS02160
uniprot id: A0A140E4H7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1538553:JT25 RS17730
gene id: 1538553:JT25_RS17730
uniprot id: A0A126T943
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS15870
gene id: 1538553:JT25_RS15870
uniprot id: A0A126T777
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1538553:JT25 RS18060
gene id: 1538553:JT25_RS18060
uniprot id: A0A126T8I7
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1538553:JT25 RS09510
gene id: 1538553:JT25_RS09510
uniprot id: A0A126T3Q6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1538553:JT25 RS18040
gene id: 1538553:JT25_RS18040
uniprot id: A0A126T8G4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS15620
gene id: 1538553:JT25_RS15620
uniprot id: A0A126T760
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1538553:JT25 RS23200
gene id: 1538553:JT25_RS23200
uniprot id: A0A140E7I3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1538553:JT25 RS11735
gene id: 1538553:JT25_RS11735
uniprot id: A0A126T4Z6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS17185
gene id: 1538553:JT25_RS17185
uniprot id: A0A126T7Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1538553:JT25 RS05875
gene id: 1538553:JT25_RS05875
uniprot id: A0A126T1R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1538553:JT25 RS12640
gene id: 1538553:JT25_RS12640
uniprot id: A0A126T6B8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1538553:JT25 RS10130
gene id: 1538553:JT25_RS10130
uniprot id: A0A126T430
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1538553:JT25 RS05810
gene id: 1538553:JT25_RS05810
uniprot id: A0A126T1Q0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1538553:JT25 RS08275
gene id: 1538553:JT25_RS08275
uniprot id: A0A126T345
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance.
messages: Periplasm

1538553:JT25 RS14420
gene id: 1538553:JT25_RS14420
uniprot id: A0A126T6H7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1538553:JT25 RS16890
gene id: 1538553:JT25_RS16890
uniprot id: A0A126T7W0
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1538553:JT25 RS08720
gene id: 1538553:JT25_RS08720
uniprot id: A0A126T3C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS14775
gene id: 1538553:JT25_RS14775
uniprot id: A0A126T6L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1538553:JT25 RS15010
gene id: 1538553:JT25_RS15010
uniprot id: A0A126T6Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1538553:JT25 RS14840
gene id: 1538553:JT25_RS14840
uniprot id: A0A126T6M2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1538553:JT25 RS07430
gene id: 1538553:JT25_RS07430
uniprot id: A0A126T3K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1538553:JT25 RS00825
gene id: 1538553:JT25_RS00825
uniprot id: A0A140E3R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1538553:JT25 RS21220
gene id: 1538553:JT25_RS21220
uniprot id: A0A140E6F0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1538553:JT25 RS01860
gene id: 1538553:JT25_RS01860
uniprot id: A0A140E4B7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS20450
gene id: 1538553:JT25_RS20450
uniprot id: A0A140E606
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1538553:JT25 RS14245
gene id: 1538553:JT25_RS14245
uniprot id: A0A126T781
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1538553:JT25 RS14250
gene id: 1538553:JT25_RS14250
uniprot id: A0A126T6C3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS02195
gene id: 1538553:JT25_RS02195
uniprot id: A0A140E4I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1538553:JT25 RS25745
gene id: 1538553:JT25_RS25745
uniprot id: A0A126T439
names: Subcellular Location Annotation
messages: Secreted

1538553:JT25 RS22260
gene id: 1538553:JT25_RS22260
uniprot id: A0A140E6Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1538553:JT25 RS13400
gene id: 1538553:JT25_RS13400
uniprot id: A0A126T6R6
names: Similarity
messages: Belongs to the UPF0758 family.

1538553:JT25 RS18470
gene id: 1538553:JT25_RS18470
uniprot id: A0A126T8Q7
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS21310
gene id: 1538553:JT25_RS21310
uniprot id: A0A140E6G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1538553:JT25 RS19590
gene id: 1538553:JT25_RS19590
uniprot id: A0A126TA46
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS17345
gene id: 1538553:JT25_RS17345
uniprot id: A0A126T819
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1538553:JT25 RS13900
gene id: 1538553:JT25_RS13900
uniprot id: A0A126T662
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1538553:JT25 RS07635
gene id: 1538553:JT25_RS07635
uniprot id: A0A126T2Q8
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1538553:JT25 RS10740
gene id: 1538553:JT25_RS10740
uniprot id: A0A126T4G2
names: Similarity
messages: Belongs to the YoeB family.

1538553:JT25 RS12875
gene id: 1538553:JT25_RS12875
uniprot id: A0A126T5J3
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1538553:JT25 RS17630
gene id: 1538553:JT25_RS17630
uniprot id: A0A126T931
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS12060
gene id: 1538553:JT25_RS12060
uniprot id: A0A126T544
names: Similarity
messages: Belongs to the YkuD family.

1538553:JT25 RS20390
gene id: 1538553:JT25_RS20390
uniprot id: A0A140E5Z5
names: Similarity
messages: Belongs to the peptidase C1 family.

1538553:JT25 RS08795
gene id: 1538553:JT25_RS08795
uniprot id: A0A126T3C8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1538553:JT25 RS17755
gene id: 1538553:JT25_RS17755
uniprot id: A0A126T891
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1538553:JT25 RS06095
gene id: 1538553:JT25_RS06095
uniprot id: A0A126T1W4
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1538553:JT25 RS17170
gene id: 1538553:JT25_RS17170
uniprot id: A0A126T8U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS17175
gene id: 1538553:JT25_RS17175
uniprot id: A0A126T7X9
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

1538553:JT25 RS13965
gene id: 1538553:JT25_RS13965
uniprot id: A0A126T674
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1538553:JT25 RS17700
gene id: 1538553:JT25_RS17700
uniprot id: A0A126T8D0
names: Similarity
messages: Belongs to the PhoH family.

1538553:JT25 RS10670
gene id: 1538553:JT25_RS10670
uniprot id: A0A126T5D1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1538553:JT25 RS06565
gene id: 1538553:JT25_RS06565
uniprot id: A0A126T243
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

1538553:JT25 RS05320
gene id: 1538553:JT25_RS05320
uniprot id: A0A126T1F4
names: Similarity
messages: Belongs to the UPF0250 family.

1538553:JT25 RS02750
gene id: 1538553:JT25_RS02750
uniprot id: A0A140E4U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1538553:JT25 RS08630
gene id: 1538553:JT25_RS08630
uniprot id: A0A126T396
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1538553:JT25 RS16320
gene id: 1538553:JT25_RS16320
uniprot id: A0A126T8C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1538553:JT25 RS13960
gene id: 1538553:JT25_RS13960
uniprot id: A0A126T732
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1538553:JT25 RS03540
gene id: 1538553:JT25_RS03540
uniprot id: A0A140E593
names: Similarity
messages: Belongs to the pyruvate kinase family.

1538553:JT25 RS00145
gene id: 1538553:JT25_RS00145
uniprot id: A0A140E3D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1538553:JT25 RS07640
gene id: 1538553:JT25_RS07640
uniprot id: A0A126T3P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1538553:JT25 RS14855
gene id: 1538553:JT25_RS14855
uniprot id: A0A126T6R0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1538553:JT25 RS14500
gene id: 1538553:JT25_RS14500
uniprot id: A0A126T6G1
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS04310
gene id: 1538553:JT25_RS04310
uniprot id: A0A126T0V1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1538553:JT25 RS05650
gene id: 1538553:JT25_RS05650
uniprot id: A0A126T1M6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-66 and Arg-69) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1538553:JT25 RS01755
gene id: 1538553:JT25_RS01755
uniprot id: A0A140E497
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1538553:JT25 RS15980
gene id: 1538553:JT25_RS15980
uniprot id: A0A126T795
names: Similarity
messages: Belongs to the BolA/IbaG family.

1538553:JT25 RS14430
gene id: 1538553:JT25_RS14430
uniprot id: A0A126T6J0
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1538553:JT25 RS23100
gene id: 1538553:JT25_RS23100
uniprot id: A0A140E7G4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1538553:JT25 RS19950
gene id: 1538553:JT25_RS19950
uniprot id: A0A140E5R2
names: Similarity
messages: Belongs to the glutamate synthase family.

1538553:JT25 RS22545
gene id: 1538553:JT25_RS22545
uniprot id: A0A140E755
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1538553:JT25 RS20635
gene id: 1538553:JT25_RS20635
uniprot id: A0A140E637
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1538553:JT25 RS16725
gene id: 1538553:JT25_RS16725
uniprot id: A0A126T7N6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

1538553:JT25 RS17045
gene id: 1538553:JT25_RS17045
uniprot id: A0A126T7V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS00385
gene id: 1538553:JT25_RS00385
uniprot id: A0A140E3I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS16745
gene id: 1538553:JT25_RS16745
uniprot id: A0A126T7P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1538553:JT25 RS18210
gene id: 1538553:JT25_RS18210
uniprot id: A0A126T8L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS03620
gene id: 1538553:JT25_RS03620
uniprot id: A0A140E5A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS15520
gene id: 1538553:JT25_RS15520
uniprot id: A0A126T740
names: Similarity
messages: Belongs to the CvfB family.

1538553:JT25 RS21105
gene id: 1538553:JT25_RS21105
uniprot id: A0A140E6C8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1538553:JT25 RS09965
gene id: 1538553:JT25_RS09965
uniprot id: A0A126T425
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1538553:JT25 RS10710
gene id: 1538553:JT25_RS10710
uniprot id: A0A126T4G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1538553:JT25 RS08230
gene id: 1538553:JT25_RS08230
uniprot id: A0A126T327
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS18135
gene id: 1538553:JT25_RS18135
uniprot id: A0A126T8G6
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1538553:JT25 RS06935
gene id: 1538553:JT25_RS06935
uniprot id: A0A126T2C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1538553:JT25 RS14240
gene id: 1538553:JT25_RS14240
uniprot id: A0A126T6A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1538553:JT25 RS19970
gene id: 1538553:JT25_RS19970
uniprot id: A0A140E5R6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1538553:JT25 RS17100
gene id: 1538553:JT25_RS17100
uniprot id: A0A126T815
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1538553:JT25 RS11775
gene id: 1538553:JT25_RS11775
uniprot id: A0A126T4Y5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1538553:JT25 RS23225
gene id: 1538553:JT25_RS23225
uniprot id: A0A140E7I8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS16705
gene id: 1538553:JT25_RS16705
uniprot id: A0A126T7P9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1538553:JT25 RS19910
gene id: 1538553:JT25_RS19910
uniprot id: A0A140E5Q4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS17075
gene id: 1538553:JT25_RS17075
uniprot id: A0A126T7V6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1538553:JT25 RS10735
gene id: 1538553:JT25_RS10735
uniprot id: A0A126T4G6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1538553:JT25 RS13825
gene id: 1538553:JT25_RS13825
uniprot id: A0A126T643
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1538553:JT25 RS09400
gene id: 1538553:JT25_RS09400
uniprot id: A0A126T3N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1538553:JT25 RS09525
gene id: 1538553:JT25_RS09525
uniprot id: A0A126T3T9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS08595
gene id: 1538553:JT25_RS08595
uniprot id: A0A126T377
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1538553:JT25 RS16145
gene id: 1538553:JT25_RS16145
uniprot id: A0A126T7E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1538553:JT25 RS06255
gene id: 1538553:JT25_RS06255
uniprot id: A0A126T1Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1538553:JT25 RS15085
gene id: 1538553:JT25_RS15085
uniprot id: A0A126T7Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS17090
gene id: 1538553:JT25_RS17090
uniprot id: A0A126T800
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1538553:JT25 RS17165
gene id: 1538553:JT25_RS17165
uniprot id: A0A126T7X2
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.

1538553:JT25 RS22755
gene id: 1538553:JT25_RS22755
uniprot id: A0A140E797
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1538553:JT25 RS09440
gene id: 1538553:JT25_RS09440
uniprot id: A0A126T3P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1538553:JT25 RS11975
gene id: 1538553:JT25_RS11975
uniprot id: A0A126T532
names: Similarity
messages: Belongs to the GSP E family.

1538553:JT25 RS04285
gene id: 1538553:JT25_RS04285
uniprot id: A0A126T0U6
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS14215
gene id: 1538553:JT25_RS14215
uniprot id: A0A126T6E3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1538553:JT25 RS23165
gene id: 1538553:JT25_RS23165
uniprot id: A0A140E7H6
names: Similarity
messages: Belongs to the IucA/IucC family.

1538553:JT25 RS10695
gene id: 1538553:JT25_RS10695
uniprot id: A0A126T4D2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1538553:JT25 RS17475
gene id: 1538553:JT25_RS17475
uniprot id: A0A126T836
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1538553:JT25 RS16435
gene id: 1538553:JT25_RS16435
uniprot id: A0A126T7I8
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1538553:JT25 RS10805
gene id: 1538553:JT25_RS10805
uniprot id: A0A126T4F0
names: Similarity
messages: Belongs to the WrbA family.

1538553:JT25 RS15850
gene id: 1538553:JT25_RS15850
uniprot id: A0A126T764
names: Similarity
messages: Belongs to the NifX/NifY family.

1538553:JT25 RS18010
gene id: 1538553:JT25_RS18010
uniprot id: A0A126T8H7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS13435
gene id: 1538553:JT25_RS13435
uniprot id: A0A126T5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1538553:JT25 RS20250
gene id: 1538553:JT25_RS20250
uniprot id: A0A140E5W8
names: Similarity
messages: Belongs to the Gfa family.

1538553:JT25 RS12930
gene id: 1538553:JT25_RS12930
uniprot id: A0A126T5M5
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.

1538553:JT25 RS02440
gene id: 1538553:JT25_RS02440
uniprot id: A0A140E4N3
names: Similarity
messages: Belongs to the YkuD family.

1538553:JT25 RS13635
gene id: 1538553:JT25_RS13635
uniprot id: A0A126T5Z8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1538553:JT25 RS00375
gene id: 1538553:JT25_RS00375
uniprot id: A0A140E3I0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1538553:JT25 RS03165
gene id: 1538553:JT25_RS03165
uniprot id: A0A140E523
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1538553:JT25 RS15930
gene id: 1538553:JT25_RS15930
uniprot id: A0A126T788
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS08835
gene id: 1538553:JT25_RS08835
uniprot id: A0A126T3D6
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1538553:JT25 RS16995
gene id: 1538553:JT25_RS16995
uniprot id: A0A126T7T9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1538553:JT25 RS04055
gene id: 1538553:JT25_RS04055
uniprot id: A0A140E5J3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1538553:JT25 RS13525
gene id: 1538553:JT25_RS13525
uniprot id: A0A126T5Y0
names: Similarity
messages: Belongs to the UPF0111 family.

1538553:JT25 RS05660
gene id: 1538553:JT25_RS05660
uniprot id: A0A126T1M5
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS16360
gene id: 1538553:JT25_RS16360
uniprot id: A0A126T7I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1538553:JT25 RS04420
gene id: 1538553:JT25_RS04420
uniprot id: A0A126T0X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1538553:JT25 RS06640
gene id: 1538553:JT25_RS06640
uniprot id: A0A126T251
names: Similarity
messages: Belongs to the HupF/HypC family.

1538553:JT25 RS20755
gene id: 1538553:JT25_RS20755
uniprot id: A0A140E661
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1538553:JT25 RS09790
gene id: 1538553:JT25_RS09790
uniprot id: A0A126T3Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1538553:JT25 RS10985
gene id: 1538553:JT25_RS10985
uniprot id: A0A126T4L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1538553:JT25 RS20825
gene id: 1538553:JT25_RS20825
uniprot id: A0A140E674
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS13030
gene id: 1538553:JT25_RS13030
uniprot id: A0A126T5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1538553:JT25 RS11525
gene id: 1538553:JT25_RS11525
uniprot id: A0A126T4T5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1538553:JT25 RS09615
gene id: 1538553:JT25_RS09615
uniprot id: A0A126T3S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1538553:JT25 RS04920
gene id: 1538553:JT25_RS04920
uniprot id: A0A126T2A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1538553:JT25 RS14630
gene id: 1538553:JT25_RS14630
uniprot id: A0A126T6H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1538553:JT25 RS14670
gene id: 1538553:JT25_RS14670
uniprot id: A0A126T6J9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1538553:JT25 RS15860
gene id: 1538553:JT25_RS15860
uniprot id: A0A126T767
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1538553:JT25 RS04175
gene id: 1538553:JT25_RS04175
uniprot id: A0A126T0R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1538553:JT25 RS00950
gene id: 1538553:JT25_RS00950
uniprot id: A0A140E3T7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1538553:JT25 RS07800
gene id: 1538553:JT25_RS07800
uniprot id: A0A126T2U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1538553:JT25 RS07750
gene id: 1538553:JT25_RS07750
uniprot id: A0A126T2T1
names: Similarity
messages: Belongs to the peptidase M16 family.

1538553:JT25 RS12675
gene id: 1538553:JT25_RS12675
uniprot id: A0A126T5F3
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.

1538553:JT25 RS07690
gene id: 1538553:JT25_RS07690
uniprot id: A0A126T3P6
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS10005
gene id: 1538553:JT25_RS10005
uniprot id: A0A126T423
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1538553:JT25 RS17490
gene id: 1538553:JT25_RS17490
uniprot id: A0A126T854
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1538553:JT25 RS01550
gene id: 1538553:JT25_RS01550
uniprot id: A0A140E456
names: Similarity
messages: Belongs to the YkuD family.

1538553:JT25 RS10565
gene id: 1538553:JT25_RS10565
uniprot id: A0A126T5B2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1538553:JT25 RS21970
gene id: 1538553:JT25_RS21970
uniprot id: A0A140E6U1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1538553:JT25 RS13085
gene id: 1538553:JT25_RS13085
uniprot id: A0A126T5Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1538553:JT25 RS21235
gene id: 1538553:JT25_RS21235
uniprot id: A0A140E6F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1538553:JT25 RS12375
gene id: 1538553:JT25_RS12375
uniprot id: A0A126T5B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS07260
gene id: 1538553:JT25_RS07260
uniprot id: A0A126T2I8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS11025
gene id: 1538553:JT25_RS11025
uniprot id: A0A126T4K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1538553:JT25 RS14870
gene id: 1538553:JT25_RS14870
uniprot id: A0A126T6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1538553:JT25 RS17590
gene id: 1538553:JT25_RS17590
uniprot id: A0A126T873
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1538553:JT25 RS22250
gene id: 1538553:JT25_RS22250
uniprot id: A0A140E6Z6
names: Similarity
messages: Belongs to the UPF0434 family.

1538553:JT25 RS17850
gene id: 1538553:JT25_RS17850
uniprot id: A0A126T8G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS10235
gene id: 1538553:JT25_RS10235
uniprot id: A0A126T475
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1538553:JT25 RS16500
gene id: 1538553:JT25_RS16500
uniprot id: A0A126T7P8
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1538553:JT25 RS12380
gene id: 1538553:JT25_RS12380
uniprot id: A0A126T5A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1538553:JT25 RS15440
gene id: 1538553:JT25_RS15440
uniprot id: A0A126T703
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1538553:JT25 RS07190
gene id: 1538553:JT25_RS07190
uniprot id: A0A126T2G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1538553:JT25 RS13845
gene id: 1538553:JT25_RS13845
uniprot id: A0A126T639
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1538553:JT25 RS15745
gene id: 1538553:JT25_RS15745
uniprot id: A0A126T763
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS09785
gene id: 1538553:JT25_RS09785
uniprot id: A0A126T3Y2
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS11725
gene id: 1538553:JT25_RS11725
uniprot id: A0A126T4X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1538553:JT25 RS20905
gene id: 1538553:JT25_RS20905
uniprot id: A0A140E5C5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1538553:JT25 RS06860
gene id: 1538553:JT25_RS06860
uniprot id: A0A126T292
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1538553:JT25 RS06710
gene id: 1538553:JT25_RS06710
uniprot id: A0A126T383
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1538553:JT25 RS20005
gene id: 1538553:JT25_RS20005
uniprot id: A0A140E5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1538553:JT25 RS17570
gene id: 1538553:JT25_RS17570
uniprot id: A0A126T882
names: Similarity
messages: Belongs to the citrate synthase family.

1538553:JT25 RS16740
gene id: 1538553:JT25_RS16740
uniprot id: A0A126T7S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1538553:JT25 RS18965
gene id: 1538553:JT25_RS18965
uniprot id: A0A126T8Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS16555
gene id: 1538553:JT25_RS16555
uniprot id: A0A126T7L9
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS01235
gene id: 1538553:JT25_RS01235
uniprot id: A0A140E3Z4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1538553:JT25 RS14580
gene id: 1538553:JT25_RS14580
uniprot id: A0A126T6L4
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS09840
gene id: 1538553:JT25_RS09840
uniprot id: A0A126T3Z3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1538553:JT25 RS09295
gene id: 1538553:JT25_RS09295
uniprot id: A0A126T3P4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS17455
gene id: 1538553:JT25_RS17455
uniprot id: A0A126T831
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1538553:JT25 RS18215
gene id: 1538553:JT25_RS18215
uniprot id: A0A126T8K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1538553:JT25 RS20425
gene id: 1538553:JT25_RS20425
uniprot id: A0A140E601
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1538553:JT25 RS14435
gene id: 1538553:JT25_RS14435
uniprot id: A0A126T6G0
names: Similarity
messages: Belongs to the peptidase S16 family.

1538553:JT25 RS13550
gene id: 1538553:JT25_RS13550
uniprot id: A0A126T6V3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1538553:JT25 RS15225
gene id: 1538553:JT25_RS15225
uniprot id: A0A126T6V5
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS00910
gene id: 1538553:JT25_RS00910
uniprot id: A0A140E3T2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1538553:JT25 RS03120
gene id: 1538553:JT25_RS03120
uniprot id: A0A140E515
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1538553:JT25 RS02325
gene id: 1538553:JT25_RS02325
uniprot id: A0A140E4L0
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS03295
gene id: 1538553:JT25_RS03295
uniprot id: A0A140E549
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS04130
gene id: 1538553:JT25_RS04130
uniprot id: A0A126T0N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1538553:JT25 RS22890
gene id: 1538553:JT25_RS22890
uniprot id: A0A140E7C4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS07395
gene id: 1538553:JT25_RS07395
uniprot id: A0A126T2N6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1538553:JT25 RS22655
gene id: 1538553:JT25_RS22655
uniprot id: A0A140E777
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1538553:JT25 RS19550
gene id: 1538553:JT25_RS19550
uniprot id: A0A126T996
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1538553:JT25 RS17355
gene id: 1538553:JT25_RS17355
uniprot id: A0A126T812
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1538553:JT25 RS20590
gene id: 1538553:JT25_RS20590
uniprot id: A0A140E628
names: Similarity
messages: Belongs to the GSP E family.

1538553:JT25 RS18725
gene id: 1538553:JT25_RS18725
uniprot id: A0A126T8W4
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1538553:JT25 RS19965
gene id: 1538553:JT25_RS19965
uniprot id: A0A140E5R5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1538553:JT25 RS10065
gene id: 1538553:JT25_RS10065
uniprot id: A0A126T446
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS20255
gene id: 1538553:JT25_RS20255
uniprot id: A0A140E5W9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

1538553:JT25 RS13835
gene id: 1538553:JT25_RS13835
uniprot id: A0A126T644
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1538553:JT25 RS10690
gene id: 1538553:JT25_RS10690
uniprot id: A0A126T4F1
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

1538553:JT25 RS13320
gene id: 1538553:JT25_RS13320
uniprot id: A0A126T5U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS22200
gene id: 1538553:JT25_RS22200
uniprot id: A0A140E6Y6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1538553:JT25 RS14425
gene id: 1538553:JT25_RS14425
uniprot id: A0A126T6F4
names: Similarity
messages: Belongs to the pirin family.

1538553:JT25 RS02490
gene id: 1538553:JT25_RS02490
uniprot id: A0A140E4P1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1538553:JT25 RS21325
gene id: 1538553:JT25_RS21325
uniprot id: A0A140E6H1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1538553:JT25 RS22725
gene id: 1538553:JT25_RS22725
uniprot id: A0A140E791
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1538553:JT25 RS03470
gene id: 1538553:JT25_RS03470
uniprot id: A0A140E579
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1538553:JT25 RS04945
gene id: 1538553:JT25_RS04945
uniprot id: A0A126T180
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1538553:JT25 RS21640
gene id: 1538553:JT25_RS21640
uniprot id: A0A140E6N0
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS13570
gene id: 1538553:JT25_RS13570
uniprot id: A0A126T603
names: Similarity
messages: Belongs to the NifZ family.

1538553:JT25 RS14680
gene id: 1538553:JT25_RS14680
uniprot id: A0A126T6J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1538553:JT25 RS22680
gene id: 1538553:JT25_RS22680
uniprot id: A0A140E782
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1538553:JT25 RS11940
gene id: 1538553:JT25_RS11940
uniprot id: A0A126T535
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS03650
gene id: 1538553:JT25_RS03650
uniprot id: A0A140E5B5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1538553:JT25 RS01220
gene id: 1538553:JT25_RS01220
uniprot id: A0A140E3Z1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1538553:JT25 RS11700
gene id: 1538553:JT25_RS11700
uniprot id: A0A126T512
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1538553:JT25 RS04345
gene id: 1538553:JT25_RS04345
uniprot id: A0A126T0V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1538553:JT25 RS01030
gene id: 1538553:JT25_RS01030
uniprot id: A0A140E3V3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1538553:JT25 RS22380
gene id: 1538553:JT25_RS22380
uniprot id: A0A140E722
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1538553:JT25 RS10420
gene id: 1538553:JT25_RS10420
uniprot id: A0A126T4A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1538553:JT25 RS00365
gene id: 1538553:JT25_RS00365
uniprot id: A0A140E3H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1538553:JT25 RS21425
gene id: 1538553:JT25_RS21425
uniprot id: A0A140E6I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1538553:JT25 RS10155
gene id: 1538553:JT25_RS10155
uniprot id: A0A126T452
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1538553:JT25 RS18905
gene id: 1538553:JT25_RS18905
uniprot id: A0A126T9R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS17600
gene id: 1538553:JT25_RS17600
uniprot id: A0A126T8A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1538553:JT25 RS06920
gene id: 1538553:JT25_RS06920
uniprot id: A0A126T3C4
names: Similarity
messages: Belongs to the peptidase S49 family.

1538553:JT25 RS22330
gene id: 1538553:JT25_RS22330
uniprot id: A0A140E712
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS14685
gene id: 1538553:JT25_RS14685
uniprot id: A0A126T7H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1538553:JT25 RS08695
gene id: 1538553:JT25_RS08695
uniprot id: A0A126T3A9
names: Similarity
messages: Belongs to the UPF0276 family.

1538553:JT25 RS06780
gene id: 1538553:JT25_RS06780
uniprot id: A0A126T293
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

1538553:JT25 RS00605
gene id: 1538553:JT25_RS00605
uniprot id: A0A140E3M4
names: Similarity
messages: Belongs to the FUN14 family.

1538553:JT25 RS14690
gene id: 1538553:JT25_RS14690
uniprot id: A0A126T6J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1538553:JT25 RS21635
gene id: 1538553:JT25_RS21635
uniprot id: A0A140E6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1538553:JT25 RS06635
gene id: 1538553:JT25_RS06635
uniprot id: A0A126T265
names: Similarity
messages: Belongs to the HupG/HyaE family.

1538553:JT25 RS06220
gene id: 1538553:JT25_RS06220
uniprot id: A0A126T1Y0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS01315
gene id: 1538553:JT25_RS01315
uniprot id: A0A140E410
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1538553:JT25 RS13465
gene id: 1538553:JT25_RS13465
uniprot id: A0A126T5X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1538553:JT25 RS18145
gene id: 1538553:JT25_RS18145
uniprot id: A0A126T8H9
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS10070
gene id: 1538553:JT25_RS10070
uniprot id: A0A126T417
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1538553:JT25 RS02125
gene id: 1538553:JT25_RS02125
uniprot id: A0A140E4H0
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS04770
gene id: 1538553:JT25_RS04770
uniprot id: A0A126T279
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS15395
gene id: 1538553:JT25_RS15395
uniprot id: A0A126T6X7
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1538553:JT25 RS06260
gene id: 1538553:JT25_RS06260
uniprot id: A0A126T1Y3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1538553:JT25 RS19300
gene id: 1538553:JT25_RS19300
uniprot id: A0A126T999
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1538553:JT25 RS19690
gene id: 1538553:JT25_RS19690
uniprot id: A0A140E5L0
names: Subcellular Location Annotation
messages: Cytoplasm

1538553:JT25 RS11935
gene id: 1538553:JT25_RS11935
uniprot id: A0A126T540
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1538553:JT25 RS04120
gene id: 1538553:JT25_RS04120
uniprot id: A0A126T0Q2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1538553:JT25 RS15000
gene id: 1538553:JT25_RS15000
uniprot id: A0A126T6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1538553:JT25 RS06685
gene id: 1538553:JT25_RS06685
uniprot id: A0A126T283
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1538553:JT25 RS23210
gene id: 1538553:JT25_RS23210
uniprot id: A0A140E7I5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1538553:JT25 RS11635
gene id: 1538553:JT25_RS11635
uniprot id: A0A126T4X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1538553:JT25 RS07460
gene id: 1538553:JT25_RS07460
uniprot id: A0A126T2L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1538553:JT25 RS17375
gene id: 1538553:JT25_RS17375
uniprot id: A0A126T813
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1538553:JT25 RS17925
gene id: 1538553:JT25_RS17925
uniprot id: A0A126T8C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1538553:JT25 RS08910
gene id: 1538553:JT25_RS08910
uniprot id: A0A126T999
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1538553:JT25 RS18920
gene id: 1538553:JT25_RS18920
uniprot id: A0A126T8X9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.

1538553:JT25 RS17465
gene id: 1538553:JT25_RS17465
uniprot id: A0A126T856
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1538553:JT25 RS07905
gene id: 1538553:JT25_RS07905
uniprot id: A0A126T2W7
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

1538553:JT25 RS06420
gene id: 1538553:JT25_RS06420
uniprot id: A0A126T214
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

1538553:JT25 RS12275
gene id: 1538553:JT25_RS12275
uniprot id: A0A126T594
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS20030
gene id: 1538553:JT25_RS20030
uniprot id: A0A140E5S8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1538553:JT25 RS14730
gene id: 1538553:JT25_RS14730
uniprot id: A0A126T6K7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1538553:JT25 RS22470
gene id: 1538553:JT25_RS22470
uniprot id: A0A140E740
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1538553:JT25 RS01420
gene id: 1538553:JT25_RS01420
uniprot id: A0A140E430
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS09405
gene id: 1538553:JT25_RS09405
uniprot id: A0A126T4R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1538553:JT25 RS01700
gene id: 1538553:JT25_RS01700
uniprot id: A0A140E486
names: Similarity
messages: Belongs to the GSP E family.

1538553:JT25 RS09180
gene id: 1538553:JT25_RS09180
uniprot id: A0A126T3K1
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1538553:JT25 RS14765
gene id: 1538553:JT25_RS14765
uniprot id: A0A126T6R2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1538553:JT25 RS17485
gene id: 1538553:JT25_RS17485
uniprot id: A0A126T838
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1538553:JT25 RS11795
gene id: 1538553:JT25_RS11795
uniprot id: A0A126T4Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1538553:JT25 RS01535
gene id: 1538553:JT25_RS01535
uniprot id: A0A140E453
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.
messages: Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.

1538553:JT25 RS11015
gene id: 1538553:JT25_RS11015
uniprot id: A0A126T4J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1538553:JT25 RS11755
gene id: 1538553:JT25_RS11755
uniprot id: A0A126T4Y6
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1538553:JT25 RS09930
gene id: 1538553:JT25_RS09930
uniprot id: A0A126T3Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS20490
gene id: 1538553:JT25_RS20490
uniprot id: A0A140E614
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS10715
gene id: 1538553:JT25_RS10715
uniprot id: A0A126T4D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1538553:JT25 RS10095
gene id: 1538553:JT25_RS10095
uniprot id: A0A126T428
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1538553:JT25 RS21600
gene id: 1538553:JT25_RS21600
uniprot id: A0A140E6M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS24410
gene id: 1538553:JT25_RS24410
uniprot id: A0A140E3T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1538553:JT25 RS03930
gene id: 1538553:JT25_RS03930
uniprot id: A0A140E5G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1538553:JT25 RS16370
gene id: 1538553:JT25_RS16370
uniprot id: A0A126T8D5
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS23445
gene id: 1538553:JT25_RS23445
uniprot id: A0A140E7N0
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS14825
gene id: 1538553:JT25_RS14825
uniprot id: A0A126T6M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1538553:JT25 RS07135
gene id: 1538553:JT25_RS07135
uniprot id: A0A126T2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1538553:JT25 RS16065
gene id: 1538553:JT25_RS16065
uniprot id: A0A126T7C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1538553:JT25 RS21455
gene id: 1538553:JT25_RS21455
uniprot id: A0A140E6J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1538553:JT25 RS05035
gene id: 1538553:JT25_RS05035
uniprot id: A0A126T195
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1538553:JT25 RS11345
gene id: 1538553:JT25_RS11345
uniprot id: A0A126T4Q7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1538553:JT25 RS00260
gene id: 1538553:JT25_RS00260
uniprot id: A0A140E3F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1538553:JT25 RS20695
gene id: 1538553:JT25_RS20695
uniprot id: A0A140E649
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1538553:JT25 RS23420
gene id: 1538553:JT25_RS23420
uniprot id: A0A140E7M5
names: Similarity
messages: Belongs to the peptidase S8 family.

1538553:JT25 RS05890
gene id: 1538553:JT25_RS05890
uniprot id: A0A126T1R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1538553:JT25 RS02305
gene id: 1538553:JT25_RS02305
uniprot id: A0A140E4K6
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS21040
gene id: 1538553:JT25_RS21040
uniprot id: A0A140E6B6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1538553:JT25 RS08665
gene id: 1538553:JT25_RS08665
uniprot id: A0A126T3B2
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1538553:JT25 RS03320
gene id: 1538553:JT25_RS03320
uniprot id: A0A140E554
names: Similarity
messages: Belongs to the universal stress protein A family.

1538553:JT25 RS06065
gene id: 1538553:JT25_RS06065
uniprot id: A0A126T1V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1538553:JT25 RS23035
gene id: 1538553:JT25_RS23035
uniprot id: A0A140E7F1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS00725
gene id: 1538553:JT25_RS00725
uniprot id: A0A140E3P6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS12285
gene id: 1538553:JT25_RS12285
uniprot id: A0A126T5C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1538553:JT25 RS14100
gene id: 1538553:JT25_RS14100
uniprot id: A0A126T6D0
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1538553:JT25 RS07885
gene id: 1538553:JT25_RS07885
uniprot id: A0A126T2W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1538553:JT25 RS13765
gene id: 1538553:JT25_RS13765
uniprot id: A0A126T634
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1538553:JT25 RS02960
gene id: 1538553:JT25_RS02960
uniprot id: A0A140E4Y5
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

1538553:JT25 RS09355
gene id: 1538553:JT25_RS09355
uniprot id: A0A126T4P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1538553:JT25 RS16960
gene id: 1538553:JT25_RS16960
uniprot id: A0A126T7V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1538553:JT25 RS15990
gene id: 1538553:JT25_RS15990
uniprot id: A0A126T7B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1538553:JT25 RS10140
gene id: 1538553:JT25_RS10140
uniprot id: A0A126T429
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS04735
gene id: 1538553:JT25_RS04735
uniprot id: A0A126T141
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1538553:JT25 RS11080
gene id: 1538553:JT25_RS11080
uniprot id: A0A126T4M1
names: Subcellular Location Annotation
messages: Cytoplasm

1538553:JT25 RS05465
gene id: 1538553:JT25_RS05465
uniprot id: A0A126T1I3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1538553:JT25 RS01035
gene id: 1538553:JT25_RS01035
uniprot id: A0A140E3V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1538553:JT25 RS22460
gene id: 1538553:JT25_RS22460
uniprot id: A0A140E738
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1538553:JT25 RS04665
gene id: 1538553:JT25_RS04665
uniprot id: A0A126T261
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1538553:JT25 RS08745
gene id: 1538553:JT25_RS08745
uniprot id: A0A126T3B9
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

1538553:JT25 RS12925
gene id: 1538553:JT25_RS12925
uniprot id: A0A126T5K3
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS04905
gene id: 1538553:JT25_RS04905
uniprot id: A0A126T161
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1538553:JT25 RS14835
gene id: 1538553:JT25_RS14835
uniprot id: A0A126T7K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1538553:JT25 RS10800
gene id: 1538553:JT25_RS10800
uniprot id: A0A126T4I8
names: Similarity
messages: Belongs to the ArsC family.

1538553:JT25 RS16775
gene id: 1538553:JT25_RS16775
uniprot id: A0A126T7P6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1538553:JT25 RS11825
gene id: 1538553:JT25_RS11825
uniprot id: A0A126T4Z8
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS20545
gene id: 1538553:JT25_RS20545
uniprot id: A0A140E619
names: Similarity
messages: Belongs to the transposase 8 family.

1538553:JT25 RS18455
gene id: 1538553:JT25_RS18455
uniprot id: A0A126T8M7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS14400
gene id: 1538553:JT25_RS14400
uniprot id: A0A126T7B1
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS16895
gene id: 1538553:JT25_RS16895
uniprot id: A0A126T7S1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1538553:JT25 RS04425
gene id: 1538553:JT25_RS04425
uniprot id: A0A126T0X8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1538553:JT25 RS13495
gene id: 1538553:JT25_RS13495
uniprot id: A0A126T5W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
messages: Cytoplasm
messages: Homotetramer.

1538553:JT25 RS20710
gene id: 1538553:JT25_RS20710
uniprot id: A0A140E652
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1538553:JT25 RS22280
gene id: 1538553:JT25_RS22280
uniprot id: A0A140E702
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1538553:JT25 RS22555
gene id: 1538553:JT25_RS22555
uniprot id: A0A140E757
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS08325
gene id: 1538553:JT25_RS08325
uniprot id: A0A126T353
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1538553:JT25 RS18670
gene id: 1538553:JT25_RS18670
uniprot id: A0A126T8S1
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1538553:JT25 RS16245
gene id: 1538553:JT25_RS16245
uniprot id: A0A126T7E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS17080
gene id: 1538553:JT25_RS17080
uniprot id: A0A126T7X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1538553:JT25 RS13585
gene id: 1538553:JT25_RS13585
uniprot id: A0A126T5Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

1538553:JT25 RS21450
gene id: 1538553:JT25_RS21450
uniprot id: A0A140E6J4
names: Similarity
messages: Belongs to the hemerythrin family.

1538553:JT25 RS10785
gene id: 1538553:JT25_RS10785
uniprot id: A0A126T4H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1538553:JT25 RS21300
gene id: 1538553:JT25_RS21300
uniprot id: A0A140E6G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1538553:JT25 RS11225
gene id: 1538553:JT25_RS11225
uniprot id: A0A126T4Q8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS16210
gene id: 1538553:JT25_RS16210
uniprot id: A0A126T8A8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1538553:JT25 RS15510
gene id: 1538553:JT25_RS15510
uniprot id: A0A126T719
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1538553:JT25 RS17825
gene id: 1538553:JT25_RS17825
uniprot id: A0A126T8A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1538553:JT25 RS11010
gene id: 1538553:JT25_RS11010
uniprot id: A0A126T4L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1538553:JT25 RS01965
gene id: 1538553:JT25_RS01965
uniprot id: A0A140E4D8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1538553:JT25 RS10405
gene id: 1538553:JT25_RS10405
uniprot id: A0A126T582
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1538553:JT25 RS00790
gene id: 1538553:JT25_RS00790
uniprot id: A0A140E3Q9
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1538553:JT25 RS18105
gene id: 1538553:JT25_RS18105
uniprot id: A0A126T8F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS14715
gene id: 1538553:JT25_RS14715
uniprot id: A0A126T6Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1538553:JT25 RS07435
gene id: 1538553:JT25_RS07435
uniprot id: A0A126T2M0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1538553:JT25 RS05820
gene id: 1538553:JT25_RS05820
uniprot id: A0A126T1Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS09370
gene id: 1538553:JT25_RS09370
uniprot id: A0A126T3R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1538553:JT25 RS11760
gene id: 1538553:JT25_RS11760
uniprot id: A0A126T511
names: Similarity
messages: Belongs to the MoaD family.

1538553:JT25 RS24415
gene id: 1538553:JT25_RS24415
uniprot id: A0A140E3T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1538553:JT25 RS15985
gene id: 1538553:JT25_RS15985
uniprot id: A0A126T7F0
names: Similarity
messages: Belongs to the YciI family.

1538553:JT25 RS13940
gene id: 1538553:JT25_RS13940
uniprot id: A0A126T671
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1538553:JT25 RS08845
gene id: 1538553:JT25_RS08845
uniprot id: A0A126T3D8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1538553:JT25 RS09275
gene id: 1538553:JT25_RS09275
uniprot id: A0A126T3N0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1538553:JT25 RS13510
gene id: 1538553:JT25_RS13510
uniprot id: A0A126T5Z4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1538553:JT25 RS14415
gene id: 1538553:JT25_RS14415
uniprot id: A0A126T6D7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS01905
gene id: 1538553:JT25_RS01905
uniprot id: A0A140E4C6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS06650
gene id: 1538553:JT25_RS06650
uniprot id: A0A126T269
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1538553:JT25 RS09720
gene id: 1538553:JT25_RS09720
uniprot id: A0A126T4W3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1538553:JT25 RS13015
gene id: 1538553:JT25_RS13015
uniprot id: A0A126T5P1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS00265
gene id: 1538553:JT25_RS00265
uniprot id: A0A140E3F8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1538553:JT25 RS12990
gene id: 1538553:JT25_RS12990
uniprot id: A0A126T6I4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1538553:JT25 RS19485
gene id: 1538553:JT25_RS19485
uniprot id: A0A126T978
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1538553:JT25 RS05900
gene id: 1538553:JT25_RS05900
uniprot id: A0A126T1S9
names: Similarity
messages: Belongs to the alphaproteobacteria porin family.

1538553:JT25 RS11030
gene id: 1538553:JT25_RS11030
uniprot id: A0A126T4L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1538553:JT25 RS21420
gene id: 1538553:JT25_RS21420
uniprot id: A0A140E6I8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1538553:JT25 RS14050
gene id: 1538553:JT25_RS14050
uniprot id: A0A126T694
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1538553:JT25 RS02315
gene id: 1538553:JT25_RS02315
uniprot id: A0A140E4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1538553:JT25 RS17195
gene id: 1538553:JT25_RS17195
uniprot id: A0A126T7Y1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1538553:JT25 RS09315
gene id: 1538553:JT25_RS09315
uniprot id: A0A126T3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1538553:JT25 RS13750
gene id: 1538553:JT25_RS13750
uniprot id: A0A126T6Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1538553:JT25 RS13065
gene id: 1538553:JT25_RS13065
uniprot id: A0A126T5P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1538553:JT25 RS12670
gene id: 1538553:JT25_RS12670
uniprot id: A0A126T5I4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1538553:JT25 RS21060
gene id: 1538553:JT25_RS21060
uniprot id: A0A140E6C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1538553:JT25 RS03350
gene id: 1538553:JT25_RS03350
uniprot id: A0A140E558
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1538553:JT25 RS00335
gene id: 1538553:JT25_RS00335
uniprot id: A0A140E3H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1538553:JT25 RS00060
gene id: 1538553:JT25_RS00060
uniprot id: A0A140E3B8
names: Subcellular Location Annotation
messages: Cell inner membrane

1538553:JT25 RS15580
gene id: 1538553:JT25_RS15580
uniprot id: A0A126T773
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1538553:JT25 RS14395
gene id: 1538553:JT25_RS14395
uniprot id: A0A126T6E8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1538553:JT25 RS06735
gene id: 1538553:JT25_RS06735
uniprot id: A0A126T291
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1538553:JT25 RS04645
gene id: 1538553:JT25_RS04645
uniprot id: A0A126T116
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1538553:JT25 RS06155
gene id: 1538553:JT25_RS06155
uniprot id: A0A126T1X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1538553:JT25 RS11835
gene id: 1538553:JT25_RS11835
uniprot id: A0A126T519
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1538553:JT25 RS00275
gene id: 1538553:JT25_RS00275
uniprot id: A0A140E3G0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1538553:JT25 RS02110
gene id: 1538553:JT25_RS02110
uniprot id: A0A140E4G7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1538553:JT25 RS22195
gene id: 1538553:JT25_RS22195
uniprot id: A0A140E6Y5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1538553:JT25 RS17035
gene id: 1538553:JT25_RS17035
uniprot id: A0A126T7V5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1538553:JT25 RS22450
gene id: 1538553:JT25_RS22450
uniprot id: A0A140E736
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1538553:JT25 RS10260
gene id: 1538553:JT25_RS10260
uniprot id: A0A126T470
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1538553:JT25 RS02045
gene id: 1538553:JT25_RS02045
uniprot id: A0A140E4F4
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1538553:JT25 RS12895
gene id: 1538553:JT25_RS12895
uniprot id: A0A126T5K8
names: Similarity
messages: Belongs to the peptidase U62 family.

1538553:JT25 RS16965
gene id: 1538553:JT25_RS16965
uniprot id: A0A126T7T2
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1538553:JT25 RS09250
gene id: 1538553:JT25_RS09250
uniprot id: A0A126T3L2
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1538553:JT25 RS19955
gene id: 1538553:JT25_RS19955
uniprot id: A0A140E5R3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1538553:JT25 RS00290
gene id: 1538553:JT25_RS00290
uniprot id: A0A140E3G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1538553:JT25 RS04165
gene id: 1538553:JT25_RS04165
uniprot id: A0A126T1W6
names: Similarity
messages: Belongs to the pyruvate kinase family.

1538553:JT25 RS15550
gene id: 1538553:JT25_RS15550
uniprot id: A0A126T7Y6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1538553:JT25 RS13920
gene id: 1538553:JT25_RS13920
uniprot id: A0A126T678
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1538553:JT25 RS03375
gene id: 1538553:JT25_RS03375
uniprot id: A0A140E563
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS20940
gene id: 1538553:JT25_RS20940
uniprot id: A0A140E696
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS11425
gene id: 1538553:JT25_RS11425
uniprot id: A0A126T4T8
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS15070
gene id: 1538553:JT25_RS15070
uniprot id: A0A126T6S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1538553:JT25 RS12790
gene id: 1538553:JT25_RS12790
uniprot id: A0A126T6E9
names: Similarity
messages: Belongs to the MotB family.

1538553:JT25 RS13660
gene id: 1538553:JT25_RS13660
uniprot id: A0A126T628
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1538553:JT25 RS09995
gene id: 1538553:JT25_RS09995
uniprot id: A0A126T407
names: Similarity
messages: Belongs to the asparaginase 1 family.

1538553:JT25 RS21335
gene id: 1538553:JT25_RS21335
uniprot id: A0A140E6H2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1538553:JT25 RS07415
gene id: 1538553:JT25_RS07415
uniprot id: A0A126T2L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1538553:JT25 RS14270
gene id: 1538553:JT25_RS14270
uniprot id: A0A126T6C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1538553:JT25 RS21700
gene id: 1538553:JT25_RS21700
uniprot id: A0A140E6P1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1538553:JT25 RS19335
gene id: 1538553:JT25_RS19335
uniprot id: A0A126T949
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

1538553:JT25 RS19055
gene id: 1538553:JT25_RS19055
uniprot id: A0A126T9U2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1538553:JT25 RS11185
gene id: 1538553:JT25_RS11185
uniprot id: A0A126T5N0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1538553:JT25 RS16560
gene id: 1538553:JT25_RS16560
uniprot id: A0A126T7M4
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1538553:JT25 RS12300
gene id: 1538553:JT25_RS12300
uniprot id: A0A126T591
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS05885
gene id: 1538553:JT25_RS05885
uniprot id: A0A126T1R7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1538553:JT25 RS13415
gene id: 1538553:JT25_RS13415
uniprot id: A0A126T5W5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1538553:JT25 RS16125
gene id: 1538553:JT25_RS16125
uniprot id: A0A126T7F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1538553:JT25 RS11155
gene id: 1538553:JT25_RS11155
uniprot id: A0A126T4P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1538553:JT25 RS19445
gene id: 1538553:JT25_RS19445
uniprot id: A0A126T979
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1538553:JT25 RS12885
gene id: 1538553:JT25_RS12885
uniprot id: A0A126T5K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1538553:JT25 RS22035
gene id: 1538553:JT25_RS22035
uniprot id: A0A140E6V4
names: Similarity
messages: Belongs to the pirin family.

1538553:JT25 RS09825
gene id: 1538553:JT25_RS09825
uniprot id: A0A126T3W9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS03580
gene id: 1538553:JT25_RS03580
uniprot id: A0A140E5A1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1538553:JT25 RS18265
gene id: 1538553:JT25_RS18265
uniprot id: A0A126T8L8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.

1538553:JT25 RS03665
gene id: 1538553:JT25_RS03665
uniprot id: A0A140E5B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1538553:JT25 RS08650
gene id: 1538553:JT25_RS08650
uniprot id: A0A126T3A5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1538553:JT25 RS23365
gene id: 1538553:JT25_RS23365
uniprot id: A0A140E7L5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1538553:JT25 RS08210
gene id: 1538553:JT25_RS08210
uniprot id: A0A126T319
names: Similarity
messages: Belongs to the MotB family.

1538553:JT25 RS07165
gene id: 1538553:JT25_RS07165
uniprot id: A0A126T2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS09685
gene id: 1538553:JT25_RS09685
uniprot id: A0A126T3W2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1538553:JT25 RS06740
gene id: 1538553:JT25_RS06740
uniprot id: A0A126T272
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1538553:JT25 RS10810
gene id: 1538553:JT25_RS10810
uniprot id: A0A126T4I0
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

1538553:JT25 RS09265
gene id: 1538553:JT25_RS09265
uniprot id: A0A126T3L3
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS11550
gene id: 1538553:JT25_RS11550
uniprot id: A0A126T4X9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1538553:JT25 RS01935
gene id: 1538553:JT25_RS01935
uniprot id: A0A140E4D2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1538553:JT25 RS02090
gene id: 1538553:JT25_RS02090
uniprot id: A0A140E4G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1538553:JT25 RS12870
gene id: 1538553:JT25_RS12870
uniprot id: A0A126T5M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS17650
gene id: 1538553:JT25_RS17650
uniprot id: A0A126T8C0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1538553:JT25 RS12840
gene id: 1538553:JT25_RS12840
uniprot id: A0A126T6F9
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS00820
gene id: 1538553:JT25_RS00820
uniprot id: A0A140E3R4
names: Similarity
messages: Belongs to the UPF0225 family.

1538553:JT25 RS11810
gene id: 1538553:JT25_RS11810
uniprot id: A0A126T518
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1538553:JT25 RS07220
gene id: 1538553:JT25_RS07220
uniprot id: A0A126T3I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1538553:JT25 RS13545
gene id: 1538553:JT25_RS13545
uniprot id: A0A126T5X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1538553:JT25 RS07420
gene id: 1538553:JT25_RS07420
uniprot id: A0A126T2M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1538553:JT25 RS04045
gene id: 1538553:JT25_RS04045
uniprot id: A0A140E5J1
names: Similarity
messages: Belongs to the MlaA family.

1538553:JT25 RS08180
gene id: 1538553:JT25_RS08180
uniprot id: A0A126T320
names: Similarity
messages: Belongs to the UPF0047 family.

1538553:JT25 RS03480
gene id: 1538553:JT25_RS03480
uniprot id: A0A140E581
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1538553:JT25 RS19025
gene id: 1538553:JT25_RS19025
uniprot id: A0A126T950
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1538553:JT25 RS09980
gene id: 1538553:JT25_RS09980
uniprot id: A0A126T400
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1538553:JT25 RS08195
gene id: 1538553:JT25_RS08195
uniprot id: A0A126T329
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS15135
gene id: 1538553:JT25_RS15135
uniprot id: A0A126T7R1
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1538553:JT25 RS12160
gene id: 1538553:JT25_RS12160
uniprot id: A0A126T999
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1538553:JT25 RS13260
gene id: 1538553:JT25_RS13260
uniprot id: A0A126T5U3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS01845
gene id: 1538553:JT25_RS01845
uniprot id: A0A140E4B4
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1538553:JT25 RS14320
gene id: 1538553:JT25_RS14320
uniprot id: A0A126T6F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1538553:JT25 RS03700
gene id: 1538553:JT25_RS03700
uniprot id: A0A140E5C5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1538553:JT25 RS12770
gene id: 1538553:JT25_RS12770
uniprot id: A0A126T5K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1538553:JT25 RS12920
gene id: 1538553:JT25_RS12920
uniprot id: A0A126T5N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1538553:JT25 RS06520
gene id: 1538553:JT25_RS06520
uniprot id: A0A126T232
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1538553:JT25 RS07235
gene id: 1538553:JT25_RS07235
uniprot id: A0A126T2K3
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1538553:JT25 RS07185
gene id: 1538553:JT25_RS07185
uniprot id: A0A126T2J5
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1538553:JT25 RS22245
gene id: 1538553:JT25_RS22245
uniprot id: A0A140E6Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1538553:JT25 RS07875
gene id: 1538553:JT25_RS07875
uniprot id: A0A126T2V4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1538553:JT25 RS03975
gene id: 1538553:JT25_RS03975
uniprot id: A0A140E5H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1538553:JT25 RS06010
gene id: 1538553:JT25_RS06010
uniprot id: A0A126T1T9
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

1538553:JT25 RS17805
gene id: 1538553:JT25_RS17805
uniprot id: A0A126T8A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1538553:JT25 RS17530
gene id: 1538553:JT25_RS17530
uniprot id: A0A126T917
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS11260
gene id: 1538553:JT25_RS11260
uniprot id: A0A126T4P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS13855
gene id: 1538553:JT25_RS13855
uniprot id: A0A126T633
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1538553:JT25 RS17095
gene id: 1538553:JT25_RS17095
uniprot id: A0A126T7W1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1538553:JT25 RS12050
gene id: 1538553:JT25_RS12050
uniprot id: A0A126T561
names: Similarity
messages: Belongs to the YkuD family.

1538553:JT25 RS04230
gene id: 1538553:JT25_RS04230
uniprot id: A0A126T0T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1538553:JT25 RS08145
gene id: 1538553:JT25_RS08145
uniprot id: A0A126T324
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1538553:JT25 RS03140
gene id: 1538553:JT25_RS03140
uniprot id: A0A140E519
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1538553:JT25 RS14810
gene id: 1538553:JT25_RS14810
uniprot id: A0A126T6L8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1538553:JT25 RS12745
gene id: 1538553:JT25_RS12745
uniprot id: A0A126T5H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1538553:JT25 RS20205
gene id: 1538553:JT25_RS20205
uniprot id: A0A140E5W0
names: Similarity
messages: Belongs to the CTP synthase family.

1538553:JT25 RS18510
gene id: 1538553:JT25_RS18510
uniprot id: A0A126T8S4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS00970
gene id: 1538553:JT25_RS00970
uniprot id: A0A140E3U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1538553:JT25 RS07070
gene id: 1538553:JT25_RS07070
uniprot id: A0A126T3F1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1538553:JT25 RS11865
gene id: 1538553:JT25_RS11865
uniprot id: A0A126T506
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1538553:JT25 RS18700
gene id: 1538553:JT25_RS18700
uniprot id: A0A126T8T3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1538553:JT25 RS13300
gene id: 1538553:JT25_RS13300
uniprot id: A0A126T6P6
names: Similarity
messages: Belongs to the SCO1/2 family.

1538553:JT25 RS00380
gene id: 1538553:JT25_RS00380
uniprot id: A0A140E3I1
names: Similarity
messages: Belongs to the hemerythrin family.

1538553:JT25 RS22945
gene id: 1538553:JT25_RS22945
uniprot id: A0A140E7D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS06835
gene id: 1538553:JT25_RS06835
uniprot id: A0A126T2A3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1538553:JT25 RS01895
gene id: 1538553:JT25_RS01895
uniprot id: A0A140E4C4
names: Similarity
messages: Belongs to the MEMO1 family.

1538553:JT25 RS16415
gene id: 1538553:JT25_RS16415
uniprot id: A0A126T7H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS17680
gene id: 1538553:JT25_RS17680
uniprot id: A0A126T934
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1538553:JT25 RS12695
gene id: 1538553:JT25_RS12695
uniprot id: A0A126T5G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1538553:JT25 RS18380
gene id: 1538553:JT25_RS18380
uniprot id: A0A126T9F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Cytoplasm

1538553:JT25 RS22560
gene id: 1538553:JT25_RS22560
uniprot id: A0A140E758
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1538553:JT25 RS18730
gene id: 1538553:JT25_RS18730
uniprot id: A0A126T8W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1538553:JT25 RS01205
gene id: 1538553:JT25_RS01205
uniprot id: A0A140E3Y8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1538553:JT25 RS07890
gene id: 1538553:JT25_RS07890
uniprot id: A0A126T2W4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1538553:JT25 RS16540
gene id: 1538553:JT25_RS16540
uniprot id: A0A126T7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1538553:JT25 RS09235
gene id: 1538553:JT25_RS09235
uniprot id: A0A126T3M6
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS08975
gene id: 1538553:JT25_RS08975
uniprot id: A0A126T3G6
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1538553:JT25 RS01140
gene id: 1538553:JT25_RS01140
uniprot id: A0A140E3X5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1538553:JT25 RS15925
gene id: 1538553:JT25_RS15925
uniprot id: A0A126T7B9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1538553:JT25 RS01480
gene id: 1538553:JT25_RS01480
uniprot id: A0A140E442
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS19990
gene id: 1538553:JT25_RS19990
uniprot id: A0A140E5S0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1538553:JT25 RS18385
gene id: 1538553:JT25_RS18385
uniprot id: A0A126T8M1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

1538553:JT25 RS15435
gene id: 1538553:JT25_RS15435
uniprot id: A0A126T6Z6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1538553:JT25 RS14540
gene id: 1538553:JT25_RS14540
uniprot id: A0A126T6L9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1538553:JT25 RS04940
gene id: 1538553:JT25_RS04940
uniprot id: A0A126T179
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1538553:JT25 RS04290
gene id: 1538553:JT25_RS04290
uniprot id: A0A126T0U3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1538553:JT25 RS14780
gene id: 1538553:JT25_RS14780
uniprot id: A0A126T6L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1538553:JT25 RS09230
gene id: 1538553:JT25_RS09230
uniprot id: A0A126T3K9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1538553:JT25 RS02785
gene id: 1538553:JT25_RS02785
uniprot id: A0A140E4V0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1538553:JT25 RS18745
gene id: 1538553:JT25_RS18745
uniprot id: A0A126T9N3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1538553:JT25 RS01850
gene id: 1538553:JT25_RS01850
uniprot id: A0A140E4B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS12985
gene id: 1538553:JT25_RS12985
uniprot id: A0A126T5M2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1538553:JT25 RS05960
gene id: 1538553:JT25_RS05960
uniprot id: A0A126T1T1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1538553:JT25 RS12775
gene id: 1538553:JT25_RS12775
uniprot id: A0A126T5H3
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1538553:JT25 RS04300
gene id: 1538553:JT25_RS04300
uniprot id: A0A126T0U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS04355
gene id: 1538553:JT25_RS04355
uniprot id: A0A126T0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1538553:JT25 RS18020
gene id: 1538553:JT25_RS18020
uniprot id: A0A126T8H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1538553:JT25 RS04375
gene id: 1538553:JT25_RS04375
uniprot id: A0A126T0W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1538553:JT25 RS15650
gene id: 1538553:JT25_RS15650
uniprot id: A0A126T803
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1538553:JT25 RS06525
gene id: 1538553:JT25_RS06525
uniprot id: A0A126T245
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1538553:JT25 RS15055
gene id: 1538553:JT25_RS15055
uniprot id: A0A126T6V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1538553:JT25 RS20190
gene id: 1538553:JT25_RS20190
uniprot id: A0A140E5V7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1538553:JT25 RS15040
gene id: 1538553:JT25_RS15040
uniprot id: A0A126T6R1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1538553:JT25 RS14310
gene id: 1538553:JT25_RS14310
uniprot id: A0A126T6C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1538553:JT25 RS18260
gene id: 1538553:JT25_RS18260
uniprot id: A0A126T8M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1538553:JT25 RS07730
gene id: 1538553:JT25_RS07730
uniprot id: A0A126T2U5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1538553:JT25 RS08290
gene id: 1538553:JT25_RS08290
uniprot id: A0A126T326
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS23500
gene id: 1538553:JT25_RS23500
uniprot id: A0A140E7P1
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS16030
gene id: 1538553:JT25_RS16030
uniprot id: A0A126T7A3
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1538553:JT25 RS25230
gene id: 1538553:JT25_RS25230
uniprot id: A0A126T0T8
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS00325
gene id: 1538553:JT25_RS00325
uniprot id: A0A140E3H0
names: Similarity
messages: Belongs to the UPF0260 family.

1538553:JT25 RS14535
gene id: 1538553:JT25_RS14535
uniprot id: A0A126T6H6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS18740
gene id: 1538553:JT25_RS18740
uniprot id: A0A126T8T5
names: Similarity
messages: Belongs to the fructosamine kinase family.

1538553:JT25 RS19985
gene id: 1538553:JT25_RS19985
uniprot id: A0A140E5R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1538553:JT25 RS14975
gene id: 1538553:JT25_RS14975
uniprot id: A0A126T6Q4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1538553:JT25 RS15780
gene id: 1538553:JT25_RS15780
uniprot id: A0A126T755
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1538553:JT25 RS15390
gene id: 1538553:JT25_RS15390
uniprot id: A0A126T6Z4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1538553:JT25 RS02510
gene id: 1538553:JT25_RS02510
uniprot id: A0A140E4P5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1538553:JT25 RS07595
gene id: 1538553:JT25_RS07595
uniprot id: A0A126T2Q6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS04745
gene id: 1538553:JT25_RS04745
uniprot id: A0A126T138
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1538553:JT25 RS00735
gene id: 1538553:JT25_RS00735
uniprot id: A0A140E3P8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1538553:JT25 RS11370
gene id: 1538553:JT25_RS11370
uniprot id: A0A126T4T2
names: Similarity
messages: Belongs to the UPF0276 family.

1538553:JT25 RS11350
gene id: 1538553:JT25_RS11350
uniprot id: A0A126T5Q8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.

1538553:JT25 RS07180
gene id: 1538553:JT25_RS07180
uniprot id: A0A126T2G4
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1538553:JT25 RS18200
gene id: 1538553:JT25_RS18200
uniprot id: A0A126T8P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS04935
gene id: 1538553:JT25_RS04935
uniprot id: A0A126T178
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1538553:JT25 RS17785
gene id: 1538553:JT25_RS17785
uniprot id: A0A126T895
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

1538553:JT25 RS20200
gene id: 1538553:JT25_RS20200
uniprot id: A0A140E5V9
names: Subcellular Location Annotation
messages: Lipid droplet

1538553:JT25 RS23375
gene id: 1538553:JT25_RS23375
uniprot id: A0A140E7L7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS02095
gene id: 1538553:JT25_RS02095
uniprot id: A0A140E4G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS13470
gene id: 1538553:JT25_RS13470
uniprot id: A0A126T5Y3
names: Subcellular Location Annotation
messages: Cytoplasm

1538553:JT25 RS05995
gene id: 1538553:JT25_RS05995
uniprot id: A0A126T1U5
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1538553:JT25 RS13410
gene id: 1538553:JT25_RS13410
uniprot id: A0A126T5W9
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1538553:JT25 RS04880
gene id: 1538553:JT25_RS04880
uniprot id: A0A126T163
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1538553:JT25 RS17275
gene id: 1538553:JT25_RS17275
uniprot id: A0A126T7Z9
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1538553:JT25 RS21205
gene id: 1538553:JT25_RS21205
uniprot id: A0A140E6E7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1538553:JT25 RS22665
gene id: 1538553:JT25_RS22665
uniprot id: A0A140E779
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS13340
gene id: 1538553:JT25_RS13340
uniprot id: A0A126T5V0
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS07465
gene id: 1538553:JT25_RS07465
uniprot id: A0A126T2M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS09050
gene id: 1538553:JT25_RS09050
uniprot id: A0A126T4G8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1538553:JT25 RS03510
gene id: 1538553:JT25_RS03510
uniprot id: A0A140E587
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

1538553:JT25 RS17230
gene id: 1538553:JT25_RS17230
uniprot id: A0A126T806
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1538553:JT25 RS18950
gene id: 1538553:JT25_RS18950
uniprot id: A0A126T8X6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1538553:JT25 RS21075
gene id: 1538553:JT25_RS21075
uniprot id: A0A140E6C3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS12075
gene id: 1538553:JT25_RS12075
uniprot id: A0A126T567
names: Subcellular Location Annotation
messages: Cytoplasm

1538553:JT25 RS05470
gene id: 1538553:JT25_RS05470
uniprot id: A0A126T1I6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1538553:JT25 RS20405
gene id: 1538553:JT25_RS20405
uniprot id: A0A140E5Z7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS21400
gene id: 1538553:JT25_RS21400
uniprot id: A0A140E6I4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1538553:JT25 RS04650
gene id: 1538553:JT25_RS04650
uniprot id: A0A126T112
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1538553:JT25 RS09955
gene id: 1538553:JT25_RS09955
uniprot id: A0A126T414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1538553:JT25 RS13815
gene id: 1538553:JT25_RS13815
uniprot id: A0A126T647
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1538553:JT25 RS17795
gene id: 1538553:JT25_RS17795
uniprot id: A0A126T8B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS05730
gene id: 1538553:JT25_RS05730
uniprot id: A0A126T2P4
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1538553:JT25 RS22020
gene id: 1538553:JT25_RS22020
uniprot id: A0A140E6V1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS14725
gene id: 1538553:JT25_RS14725
uniprot id: A0A126T6K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1538553:JT25 RS05760
gene id: 1538553:JT25_RS05760
uniprot id: A0A126T1N7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1538553:JT25 RS13955
gene id: 1538553:JT25_RS13955
uniprot id: A0A126T654
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1538553:JT25 RS09970
gene id: 1538553:JT25_RS09970
uniprot id: A0A126T3Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1538553:JT25 RS00815
gene id: 1538553:JT25_RS00815
uniprot id: A0A140E3R3
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS12280
gene id: 1538553:JT25_RS12280
uniprot id: A0A126T589
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1538553:JT25 RS06765
gene id: 1538553:JT25_RS06765
uniprot id: A0A126T298
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1538553:JT25 RS15905
gene id: 1538553:JT25_RS15905
uniprot id: A0A126T853
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1538553:JT25 RS19925
gene id: 1538553:JT25_RS19925
uniprot id: A0A140E5Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1538553:JT25 RS16290
gene id: 1538553:JT25_RS16290
uniprot id: A0A126T7I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Membrane

1538553:JT25 RS16380
gene id: 1538553:JT25_RS16380
uniprot id: A0A126T7I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1538553:JT25 RS15630
gene id: 1538553:JT25_RS15630
uniprot id: A0A126T782
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1538553:JT25 RS13385
gene id: 1538553:JT25_RS13385
uniprot id: A0A126T5U4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1538553:JT25 RS14700
gene id: 1538553:JT25_RS14700
uniprot id: A0A126T6I9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1538553:JT25 RS22055
gene id: 1538553:JT25_RS22055
uniprot id: A0A140E6V8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS23030
gene id: 1538553:JT25_RS23030
uniprot id: A0A140E7F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1538553:JT25 RS15960
gene id: 1538553:JT25_RS15960
uniprot id: A0A126T784
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1538553:JT25 RS06760
gene id: 1538553:JT25_RS06760
uniprot id: A0A126T393
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1538553:JT25 RS10705
gene id: 1538553:JT25_RS10705
uniprot id: A0A126T4D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1538553:JT25 RS04000
gene id: 1538553:JT25_RS04000
uniprot id: A0A140E5I2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1538553:JT25 RS10630
gene id: 1538553:JT25_RS10630
uniprot id: A0A126T4E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS06175
gene id: 1538553:JT25_RS06175
uniprot id: A0A126T1X2
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS07380
gene id: 1538553:JT25_RS07380
uniprot id: A0A126T3K3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1538553:JT25 RS09270
gene id: 1538553:JT25_RS09270
uniprot id: A0A126T3P2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1538553:JT25 RS09850
gene id: 1538553:JT25_RS09850
uniprot id: A0A126T3Y6
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1538553:JT25 RS15740
gene id: 1538553:JT25_RS15740
uniprot id: A0A126T759
names: Similarity
messages: Belongs to the AHA1 family.

1538553:JT25 RS16735
gene id: 1538553:JT25_RS16735
uniprot id: A0A126T7P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1538553:JT25 RS10920
gene id: 1538553:JT25_RS10920
uniprot id: A0A126T5H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS16170
gene id: 1538553:JT25_RS16170
uniprot id: A0A126T7D9
names: Similarity
messages: Belongs to the Smg family.

1538553:JT25 RS16075
gene id: 1538553:JT25_RS16075
uniprot id: A0A126T7E8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS19980
gene id: 1538553:JT25_RS19980
uniprot id: A0A140E5R8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS07370
gene id: 1538553:JT25_RS07370
uniprot id: A0A126T2L1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1538553:JT25 RS14220
gene id: 1538553:JT25_RS14220
uniprot id: A0A126T6B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1538553:JT25 RS13645
gene id: 1538553:JT25_RS13645
uniprot id: A0A126T5Z7
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1538553:JT25 RS11820
gene id: 1538553:JT25_RS11820
uniprot id: A0A126T5Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

1538553:JT25 RS12240
gene id: 1538553:JT25_RS12240
uniprot id: A0A126T578
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1538553:JT25 RS00460
gene id: 1538553:JT25_RS00460
uniprot id: A0A140E3J7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1538553:JT25 RS22265
gene id: 1538553:JT25_RS22265
uniprot id: A0A140E6Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1538553:JT25 RS09030
gene id: 1538553:JT25_RS09030
uniprot id: A0A126T3J1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1538553:JT25 RS07045
gene id: 1538553:JT25_RS07045
uniprot id: A0A126T2F1
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1538553:JT25 RS22775
gene id: 1538553:JT25_RS22775
uniprot id: A0A140E7A1
names: Function
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.

1538553:JT25 RS15635
gene id: 1538553:JT25_RS15635
uniprot id: A0A126T736
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1538553:JT25 RS00780
gene id: 1538553:JT25_RS00780
uniprot id: A0A140E3Q7
names: Similarity
messages: Belongs to the YciI family.

1538553:JT25 RS06865
gene id: 1538553:JT25_RS06865
uniprot id: A0A126T3B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1538553:JT25 RS22130
gene id: 1538553:JT25_RS22130
uniprot id: A0A140E6X3
names: Similarity
messages: Belongs to the XFP family.

1538553:JT25 RS20725
gene id: 1538553:JT25_RS20725
uniprot id: A0A140E655
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1538553:JT25 RS14340
gene id: 1538553:JT25_RS14340
uniprot id: A0A126T6D2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1538553:JT25 RS06605
gene id: 1538553:JT25_RS06605
uniprot id: A0A126T257
names: Similarity
messages: Belongs to the HupJ family.

1538553:JT25 RS01980
gene id: 1538553:JT25_RS01980
uniprot id: A0A140E4E1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1538553:JT25 RS09775
gene id: 1538553:JT25_RS09775
uniprot id: A0A126T3V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1538553:JT25 RS04810
gene id: 1538553:JT25_RS04810
uniprot id: A0A126T150
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1538553:JT25 RS02155
gene id: 1538553:JT25_RS02155
uniprot id: A0A140E4H6
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1538553:JT25 RS04020
gene id: 1538553:JT25_RS04020
uniprot id: A0A140E5I6
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1538553:JT25 RS18005
gene id: 1538553:JT25_RS18005
uniprot id: A0A126T8D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1538553:JT25 RS03300
gene id: 1538553:JT25_RS03300
uniprot id: A0A140E550
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1538553:JT25 RS21355
gene id: 1538553:JT25_RS21355
uniprot id: A0A140E6H5
names: Similarity
messages: Belongs to the histone deacetylase family.

1538553:JT25 RS01695
gene id: 1538553:JT25_RS01695
uniprot id: A0A140E485
names: Similarity
messages: Belongs to the MlaA family.

1538553:JT25 RS00350
gene id: 1538553:JT25_RS00350
uniprot id: A0A140E3H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1538553:JT25 RS21170
gene id: 1538553:JT25_RS21170
uniprot id: A0A140E6E1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1538553:JT25 RS07740
gene id: 1538553:JT25_RS07740
uniprot id: A0A126T3Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1538553:JT25 RS10685
gene id: 1538553:JT25_RS10685
uniprot id: A0A126T4F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS22190
gene id: 1538553:JT25_RS22190
uniprot id: A0A140E6Y4
names: Similarity
messages: Belongs to the YkuD family.

1538553:JT25 RS03950
gene id: 1538553:JT25_RS03950
uniprot id: A0A140E5H2
names: Similarity
messages: Belongs to the aspartokinase family.

1538553:JT25 RS15825
gene id: 1538553:JT25_RS15825
uniprot id: A0A126T798
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1538553:JT25 RS16920
gene id: 1538553:JT25_RS16920
uniprot id: A0A126T8P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1538553:JT25 RS21265
gene id: 1538553:JT25_RS21265
uniprot id: A0A140E6F9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS04395
gene id: 1538553:JT25_RS04395
uniprot id: A0A126T0W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1538553:JT25 RS16025
gene id: 1538553:JT25_RS16025
uniprot id: A0A126T7D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS02765
gene id: 1538553:JT25_RS02765
uniprot id: A0A140E4U6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1538553:JT25 RS13305
gene id: 1538553:JT25_RS13305
uniprot id: A0A126T5U6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1538553:JT25 RS19490
gene id: 1538553:JT25_RS19490
uniprot id: A0A126TA22
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1538553:JT25 RS15570
gene id: 1538553:JT25_RS15570
uniprot id: A0A126T750
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1538553:JT25 RS10290
gene id: 1538553:JT25_RS10290
uniprot id: A0A126T465
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1538553:JT25 RS11670
gene id: 1538553:JT25_RS11670
uniprot id: A0A126T5W7
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS12900
gene id: 1538553:JT25_RS12900
uniprot id: A0A126T5L6
names: Similarity
messages: Belongs to the peptidase U62 family.

1538553:JT25 RS00835
gene id: 1538553:JT25_RS00835
uniprot id: A0A140E3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1538553:JT25 RS11270
gene id: 1538553:JT25_RS11270
uniprot id: A0A126T4P2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS23370
gene id: 1538553:JT25_RS23370
uniprot id: A0A140E7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1538553:JT25 RS09975
gene id: 1538553:JT25_RS09975
uniprot id: A0A126T427
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1538553:JT25 RS05855
gene id: 1538553:JT25_RS05855
uniprot id: A0A126T1R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1538553:JT25 RS10000
gene id: 1538553:JT25_RS10000
uniprot id: A0A126T426
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1538553:JT25 RS04845
gene id: 1538553:JT25_RS04845
uniprot id: A0A126T162
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1538553:JT25 RS15190
gene id: 1538553:JT25_RS15190
uniprot id: A0A126T6U0
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1538553:JT25 RS21850
gene id: 1538553:JT25_RS21850
uniprot id: A0A140E6R8
names: Similarity
messages: Belongs to the transposase 8 family.

1538553:JT25 RS01750
gene id: 1538553:JT25_RS01750
uniprot id: A0A140E496
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1538553:JT25 RS00505
gene id: 1538553:JT25_RS00505
uniprot id: A0A140E3K6
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS15615
gene id: 1538553:JT25_RS15615
uniprot id: A0A126T722
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS02185
gene id: 1538553:JT25_RS02185
uniprot id: A0A140E4I2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1538553:JT25 RS06840
gene id: 1538553:JT25_RS06840
uniprot id: A0A126T2A9
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

1538553:JT25 RS05510
gene id: 1538553:JT25_RS05510
uniprot id: A0A126T1J1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1538553:JT25 RS13640
gene id: 1538553:JT25_RS13640
uniprot id: A0A126T618
names: Similarity
messages: Belongs to the BolA/IbaG family.

1538553:JT25 RS10010
gene id: 1538553:JT25_RS10010
uniprot id: A0A126T412
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1538553:JT25 RS17180
gene id: 1538553:JT25_RS17180
uniprot id: A0A126T7Z7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1538553:JT25 RS16250
gene id: 1538553:JT25_RS16250
uniprot id: A0A126T7J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1538553:JT25 RS18055
gene id: 1538553:JT25_RS18055
uniprot id: A0A126T8F0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1538553:JT25 RS12850
gene id: 1538553:JT25_RS12850
uniprot id: A0A126T5K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

1538553:JT25 RS04550
gene id: 1538553:JT25_RS04550
uniprot id: A0A126T0Z6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS07265
gene id: 1538553:JT25_RS07265
uniprot id: A0A126T2J3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1538553:JT25 RS17640
gene id: 1538553:JT25_RS17640
uniprot id: A0A126T883
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1538553:JT25 RS14070
gene id: 1538553:JT25_RS14070
uniprot id: A0A126T751
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1538553:JT25 RS06105
gene id: 1538553:JT25_RS06105
uniprot id: A0A126T1W3
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1538553:JT25 RS02690
gene id: 1538553:JT25_RS02690
uniprot id: A0A140E4T1
names: Similarity
messages: Belongs to the YciI family.

1538553:JT25 RS17720
gene id: 1538553:JT25_RS17720
uniprot id: A0A126T8B2
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1538553:JT25 RS12700
gene id: 1538553:JT25_RS12700
uniprot id: A0A126T5H9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1538553:JT25 RS17880
gene id: 1538553:JT25_RS17880
uniprot id: A0A126T964
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS17860
gene id: 1538553:JT25_RS17860
uniprot id: A0A126T8F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1538553:JT25 RS05055
gene id: 1538553:JT25_RS05055
uniprot id: A0A126T192
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1538553:JT25 RS21270
gene id: 1538553:JT25_RS21270
uniprot id: A0A140E6G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1538553:JT25 RS12255
gene id: 1538553:JT25_RS12255
uniprot id: A0A126T670
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1538553:JT25 RS20980
gene id: 1538553:JT25_RS20980
uniprot id: A0A140E6A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methanol dehydrogenase subunit 2 family.
messages: Catalyzes the oxidation of primary alcohols including methanol.
messages: Heterotetramer composed of 2 alpha and 2 beta subunits.

1538553:JT25 RS17370
gene id: 1538553:JT25_RS17370
uniprot id: A0A126T837
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1538553:JT25 RS23535
gene id: 1538553:JT25_RS23535
uniprot id: A0A126T999
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1538553:JT25 RS20965
gene id: 1538553:JT25_RS20965
uniprot id: A0A140E6A1
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

1538553:JT25 RS13420
gene id: 1538553:JT25_RS13420
uniprot id: A0A126T5X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1538553:JT25 RS07610
gene id: 1538553:JT25_RS07610
uniprot id: A0A126T2N8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1538553:JT25 RS14045
gene id: 1538553:JT25_RS14045
uniprot id: A0A126T686
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS10760
gene id: 1538553:JT25_RS10760
uniprot id: A0A126T4H1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS12065
gene id: 1538553:JT25_RS12065
uniprot id: A0A126T581
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1538553:JT25 RS15895
gene id: 1538553:JT25_RS15895
uniprot id: A0A126T797
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1538553:JT25 RS21210
gene id: 1538553:JT25_RS21210
uniprot id: A0A140E6E8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS02000
gene id: 1538553:JT25_RS02000
uniprot id: A0A140E4E5
names: Similarity
messages: Belongs to the P(II) protein family.

1538553:JT25 RS06275
gene id: 1538553:JT25_RS06275
uniprot id: A0A126T1Z5
names: Similarity
messages: Belongs to the NifX/NifY family.

1538553:JT25 RS06350
gene id: 1538553:JT25_RS06350
uniprot id: A0A126T202
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1538553:JT25 RS16055
gene id: 1538553:JT25_RS16055
uniprot id: A0A126T880
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1538553:JT25 RS14195
gene id: 1538553:JT25_RS14195
uniprot id: A0A126T771
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1538553:JT25 RS18015
gene id: 1538553:JT25_RS18015
uniprot id: A0A126T8G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1538553:JT25 RS13605
gene id: 1538553:JT25_RS13605
uniprot id: A0A126T608
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

1538553:JT25 RS19790
gene id: 1538553:JT25_RS19790
uniprot id: A0A140E5N0
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1538553:JT25 RS16445
gene id: 1538553:JT25_RS16445
uniprot id: A0A126T7I4
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS12735
gene id: 1538553:JT25_RS12735
uniprot id: A0A126T5H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1538553:JT25 RS13935
gene id: 1538553:JT25_RS13935
uniprot id: A0A126T667
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1538553:JT25 RS17760
gene id: 1538553:JT25_RS17760
uniprot id: A0A126T8D3
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1538553:JT25 RS15560
gene id: 1538553:JT25_RS15560
uniprot id: A0A126T729
names: Similarity
messages: Belongs to the CcdB toxin family.

1538553:JT25 RS00785
gene id: 1538553:JT25_RS00785
uniprot id: A0A140E3Q8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1538553:JT25 RS09340
gene id: 1538553:JT25_RS09340
uniprot id: A0A126T3N2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1538553:JT25 RS15765
gene id: 1538553:JT25_RS15765
uniprot id: A0A126T768
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1538553:JT25 RS17300
gene id: 1538553:JT25_RS17300
uniprot id: A0A126T849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1538553:JT25 RS09475
gene id: 1538553:JT25_RS09475
uniprot id: A0A126T3S9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1538553:JT25 RS21295
gene id: 1538553:JT25_RS21295
uniprot id: A0A140E6G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1538553:JT25 RS04405
gene id: 1538553:JT25_RS04405
uniprot id: A0A126T0X0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1538553:JT25 RS10980
gene id: 1538553:JT25_RS10980
uniprot id: A0A126T4K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1538553:JT25 RS10475
gene id: 1538553:JT25_RS10475
uniprot id: A0A126T999
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1538553:JT25 RS05715
gene id: 1538553:JT25_RS05715
uniprot id: A0A126T1N6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1538553:JT25 RS06090
gene id: 1538553:JT25_RS06090
uniprot id: A0A126T1V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1538553:JT25 RS00400
gene id: 1538553:JT25_RS00400
uniprot id: A0A140E3I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1538553:JT25 RS15965
gene id: 1538553:JT25_RS15965
uniprot id: A0A126T7A4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1538553:JT25 RS12760
gene id: 1538553:JT25_RS12760
uniprot id: A0A126T5J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1538553:JT25 RS05385
gene id: 1538553:JT25_RS05385
uniprot id: A0A126T1G3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1538553:JT25 RS20680
gene id: 1538553:JT25_RS20680
uniprot id: A0A140E646
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1538553:JT25 RS12205
gene id: 1538553:JT25_RS12205
uniprot id: A0A126T663
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1538553:JT25 RS01705
gene id: 1538553:JT25_RS01705
uniprot id: A0A140E487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1538553:JT25 RS15835
gene id: 1538553:JT25_RS15835
uniprot id: A0A126T7C5
names: Similarity
messages: Belongs to the ModE family.

1538553:JT25 RS21255
gene id: 1538553:JT25_RS21255
uniprot id: A0A140E6F7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS17750
gene id: 1538553:JT25_RS17750
uniprot id: A0A126T8D8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1538553:JT25 RS11730
gene id: 1538553:JT25_RS11730
uniprot id: A0A126T4Z4
names: Similarity
messages: Belongs to the thioredoxin family.

1538553:JT25 RS17565
gene id: 1538553:JT25_RS17565
uniprot id: A0A126T875
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1538553:JT25 RS05940
gene id: 1538553:JT25_RS05940
uniprot id: A0A126T1S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1538553:JT25 RS04975
gene id: 1538553:JT25_RS04975
uniprot id: A0A126T189
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1538553:JT25 RS05830
gene id: 1538553:JT25_RS05830
uniprot id: A0A126T2Q5
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS22675
gene id: 1538553:JT25_RS22675
uniprot id: A0A140E781
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1538553:JT25 RS16880
gene id: 1538553:JT25_RS16880
uniprot id: A0A126T7T8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1538553:JT25 RS09740
gene id: 1538553:JT25_RS09740
uniprot id: A0A126T3X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1538553:JT25 RS21625
gene id: 1538553:JT25_RS21625
uniprot id: A0A140E6M7
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS21160
gene id: 1538553:JT25_RS21160
uniprot id: A0A140E6D9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1538553:JT25 RS06560
gene id: 1538553:JT25_RS06560
uniprot id: A0A126T354
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1538553:JT25 RS03445
gene id: 1538553:JT25_RS03445
uniprot id: A0A140E574
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1538553:JT25 RS07105
gene id: 1538553:JT25_RS07105
uniprot id: A0A126T2E3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1538553:JT25 RS04160
gene id: 1538553:JT25_RS04160
uniprot id: A0A126T0S3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1538553:JT25 RS08165
gene id: 1538553:JT25_RS08165
uniprot id: A0A126T306
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS14735
gene id: 1538553:JT25_RS14735
uniprot id: A0A126T7I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1538553:JT25 RS12350
gene id: 1538553:JT25_RS12350
uniprot id: A0A126T5A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1538553:JT25 RS02365
gene id: 1538553:JT25_RS02365
uniprot id: A0A140E4L8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1538553:JT25 RS11745
gene id: 1538553:JT25_RS11745
uniprot id: A0A126T4X8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1538553:JT25 RS13345
gene id: 1538553:JT25_RS13345
uniprot id: A0A126T5U1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1538553:JT25 RS12270
gene id: 1538553:JT25_RS12270
uniprot id: A0A126T598
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1538553:JT25 RS02975
gene id: 1538553:JT25_RS02975
uniprot id: A0A140E4Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1538553:JT25 RS20435
gene id: 1538553:JT25_RS20435
uniprot id: A0A140E603
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1538553:JT25 RS13445
gene id: 1538553:JT25_RS13445
uniprot id: A0A126T5V8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1538553:JT25 RS05590
gene id: 1538553:JT25_RS05590
uniprot id: A0A126T1L7
names: Similarity
messages: Belongs to the hemerythrin family.

1538553:JT25 RS13625
gene id: 1538553:JT25_RS13625
uniprot id: A0A126T604
names: Similarity
messages: Belongs to the NifZ family.

1538553:JT25 RS00520
gene id: 1538553:JT25_RS00520
uniprot id: A0A140E3K9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1538553:JT25 RS14770
gene id: 1538553:JT25_RS14770
uniprot id: A0A126T6M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1538553:JT25 RS01925
gene id: 1538553:JT25_RS01925
uniprot id: A0A140E4D0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1538553:JT25 RS16870
gene id: 1538553:JT25_RS16870
uniprot id: A0A126T8N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1538553:JT25 RS01425
gene id: 1538553:JT25_RS01425
uniprot id: A0A140E431
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS13325
gene id: 1538553:JT25_RS13325
uniprot id: A0A126T5T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1538553:JT25 RS14845
gene id: 1538553:JT25_RS14845
uniprot id: A0A126T6P2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1538553:JT25 RS04600
gene id: 1538553:JT25_RS04600
uniprot id: A0A126T104
names: Similarity
messages: Belongs to the hemerythrin family.

1538553:JT25 RS17495
gene id: 1538553:JT25_RS17495
uniprot id: A0A126T850
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS06845
gene id: 1538553:JT25_RS06845
uniprot id: A0A126T297
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS14675
gene id: 1538553:JT25_RS14675
uniprot id: A0A126T6J4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1538553:JT25 RS05080
gene id: 1538553:JT25_RS05080
uniprot id: A0A126T1B0
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1538553:JT25 RS16665
gene id: 1538553:JT25_RS16665
uniprot id: A0A126T7M0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS21130
gene id: 1538553:JT25_RS21130
uniprot id: A0A140E6D3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1538553:JT25 RS18255
gene id: 1538553:JT25_RS18255
uniprot id: A0A126T8I6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1538553:JT25 RS05455
gene id: 1538553:JT25_RS05455
uniprot id: A0A126T1H7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1538553:JT25 RS16375
gene id: 1538553:JT25_RS16375
uniprot id: A0A126T7G5
names: Similarity
messages: Belongs to the YjdM family.

1538553:JT25 RS02105
gene id: 1538553:JT25_RS02105
uniprot id: A0A140E4G6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1538553:JT25 RS16155
gene id: 1538553:JT25_RS16155
uniprot id: A0A126T899
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1538553:JT25 RS22065
gene id: 1538553:JT25_RS22065
uniprot id: A0A140E6W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1538553:JT25 RS07805
gene id: 1538553:JT25_RS07805
uniprot id: A0A126T2U2
names: Similarity
messages: Belongs to the acylphosphatase family.

1538553:JT25 RS13115
gene id: 1538553:JT25_RS13115
uniprot id: A0A126T5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS07695
gene id: 1538553:JT25_RS07695
uniprot id: A0A126T2S6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1538553:JT25 RS10725
gene id: 1538553:JT25_RS10725
uniprot id: A0A126T4E4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS22425
gene id: 1538553:JT25_RS22425
uniprot id: A0A140E731
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS07710
gene id: 1538553:JT25_RS07710
uniprot id: A0A126T2R0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1538553:JT25 RS14255
gene id: 1538553:JT25_RS14255
uniprot id: A0A126T6C9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1538553:JT25 RS13190
gene id: 1538553:JT25_RS13190
uniprot id: A0A126T5R2
names: Similarity
messages: Belongs to the catalase family.

1538553:JT25 RS23025
gene id: 1538553:JT25_RS23025
uniprot id: A0A140E7E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1538553:JT25 RS09150
gene id: 1538553:JT25_RS09150
uniprot id: A0A126T3I5
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1538553:JT25 RS10230
gene id: 1538553:JT25_RS10230
uniprot id: A0A126T442
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1538553:JT25 RS12305
gene id: 1538553:JT25_RS12305
uniprot id: A0A126T675
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1538553:JT25 RS19130
gene id: 1538553:JT25_RS19130
uniprot id: A0A126T906
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1538553:JT25 RS06875
gene id: 1538553:JT25_RS06875
uniprot id: A0A126T296
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1538553:JT25 RS03455
gene id: 1538553:JT25_RS03455
uniprot id: A0A140E576
names: Similarity
messages: Belongs to the HesB/IscA family.

1538553:JT25 RS03725
gene id: 1538553:JT25_RS03725
uniprot id: A0A140E5C9
names: Similarity
messages: Belongs to the HsdR family.

1538553:JT25 RS16420
gene id: 1538553:JT25_RS16420
uniprot id: A0A126T8E5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1538553:JT25 RS11840
gene id: 1538553:JT25_RS11840
uniprot id: A0A126T515
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1538553:JT25 RS21135
gene id: 1538553:JT25_RS21135
uniprot id: A0A140E6D4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1538553:JT25 RS12740
gene id: 1538553:JT25_RS12740
uniprot id: A0A126T6E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1538553:JT25 RS16135
gene id: 1538553:JT25_RS16135
uniprot id: A0A126T7H9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1538553:JT25 RS22455
gene id: 1538553:JT25_RS22455
uniprot id: A0A140E737
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1538553:JT25 RS15100
gene id: 1538553:JT25_RS15100
uniprot id: A0A126T6R7
names: Similarity
messages: Belongs to the peptidase M18 family.

1538553:JT25 RS07450
gene id: 1538553:JT25_RS07450
uniprot id: A0A126T2K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1538553:JT25 RS09885
gene id: 1538553:JT25_RS09885
uniprot id: A0A126T3X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1538553:JT25 RS13910
gene id: 1538553:JT25_RS13910
uniprot id: A0A126T724
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1538553:JT25 RS19195
gene id: 1538553:JT25_RS19195
uniprot id: A0A126T959
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS15445
gene id: 1538553:JT25_RS15445
uniprot id: A0A126T6Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1538553:JT25 RS06020
gene id: 1538553:JT25_RS06020
uniprot id: A0A126T1U0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS20775
gene id: 1538553:JT25_RS20775
uniprot id: A0A140E665
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1538553:JT25 RS20445
gene id: 1538553:JT25_RS20445
uniprot id: A0A140E605
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1538553:JT25 RS21900
gene id: 1538553:JT25_RS21900
uniprot id: A0A140E6S8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1538553:JT25 RS07810
gene id: 1538553:JT25_RS07810
uniprot id: A0A126T2U7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1538553:JT25 RS15710
gene id: 1538553:JT25_RS15710
uniprot id: A0A126T758
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS22270
gene id: 1538553:JT25_RS22270
uniprot id: A0A140E700
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS00945
gene id: 1538553:JT25_RS00945
uniprot id: A0A140E3T6
names: Subcellular Location Annotation
messages: Cytoplasm

1538553:JT25 RS04015
gene id: 1538553:JT25_RS04015
uniprot id: A0A140E5I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1538553:JT25 RS22745
gene id: 1538553:JT25_RS22745
uniprot id: A0A140E795
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1538553:JT25 RS08730
gene id: 1538553:JT25_RS08730
uniprot id: A0A126T3D2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1538553:JT25 RS10700
gene id: 1538553:JT25_RS10700
uniprot id: A0A126T4H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1538553:JT25 RS12125
gene id: 1538553:JT25_RS12125
uniprot id: A0A126T577
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1538553:JT25 RS07145
gene id: 1538553:JT25_RS07145
uniprot id: A0A126T2H1
names: Similarity
messages: Belongs to the IMPACT family.

1538553:JT25 RS04010
gene id: 1538553:JT25_RS04010
uniprot id: A0A140E5I4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1538553:JT25 RS07425
gene id: 1538553:JT25_RS07425
uniprot id: A0A126T2L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS04495
gene id: 1538553:JT25_RS04495
uniprot id: A0A126T0Y1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1538553:JT25 RS15915
gene id: 1538553:JT25_RS15915
uniprot id: A0A126T796
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1538553:JT25 RS00240
gene id: 1538553:JT25_RS00240
uniprot id: A0A140E3F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS17290
gene id: 1538553:JT25_RS17290
uniprot id: A0A126T844
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS14335
gene id: 1538553:JT25_RS14335
uniprot id: A0A126T6E2
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

1538553:JT25 RS18100
gene id: 1538553:JT25_RS18100
uniprot id: A0A126T8L6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1538553:JT25 RS21430
gene id: 1538553:JT25_RS21430
uniprot id: A0A140E6J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1538553:JT25 RS05075
gene id: 1538553:JT25_RS05075
uniprot id: A0A126T2C6
names: Similarity
messages: Belongs to the GARS family.

1538553:JT25 RS13575
gene id: 1538553:JT25_RS13575
uniprot id: A0A126T5Z1
names: Similarity
messages: Belongs to the HesB/IscA family.

1538553:JT25 RS12650
gene id: 1538553:JT25_RS12650
uniprot id: A0A126T5G8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS16765
gene id: 1538553:JT25_RS16765
uniprot id: A0A126T7N8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1538553:JT25 RS16200
gene id: 1538553:JT25_RS16200
uniprot id: A0A126T7F3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1538553:JT25 RS19600
gene id: 1538553:JT25_RS19600
uniprot id: A0A126T9A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1538553:JT25 RS12425
gene id: 1538553:JT25_RS12425
uniprot id: A0A140E5J3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1538553:JT25 RS08450
gene id: 1538553:JT25_RS08450
uniprot id: A0A126T349
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1538553:JT25 RS22445
gene id: 1538553:JT25_RS22445
uniprot id: A0A140E735
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1538553:JT25 RS16760
gene id: 1538553:JT25_RS16760
uniprot id: A0A126T7R3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1538553:JT25 RS14805
gene id: 1538553:JT25_RS14805
uniprot id: A0A126T6Q2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1538553:JT25 RS21360
gene id: 1538553:JT25_RS21360
uniprot id: A0A140E6H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1538553:JT25 RS17580
gene id: 1538553:JT25_RS17580
uniprot id: A0A126T927
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1538553:JT25 RS02985
gene id: 1538553:JT25_RS02985
uniprot id: A0A140E4Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS03640
gene id: 1538553:JT25_RS03640
uniprot id: A0A140E5B3
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.

1538553:JT25 RS16240
gene id: 1538553:JT25_RS16240
uniprot id: A0A126T7H8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1538553:JT25 RS12685
gene id: 1538553:JT25_RS12685
uniprot id: A0A126T5F9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1538553:JT25 RS03090
gene id: 1538553:JT25_RS03090
uniprot id: A0A140E509
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1538553:JT25 RS12110
gene id: 1538553:JT25_RS12110
uniprot id: A0A126T554
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS20110
gene id: 1538553:JT25_RS20110
uniprot id: A0A140E5U1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1538553:JT25 RS04195
gene id: 1538553:JT25_RS04195
uniprot id: A0A126T0S6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1538553:JT25 RS20935
gene id: 1538553:JT25_RS20935
uniprot id: A0A140E695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1538553:JT25 RS04380
gene id: 1538553:JT25_RS04380
uniprot id: A0A126T0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

1538553:JT25 RS13850
gene id: 1538553:JT25_RS13850
uniprot id: A0A126T655
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1538553:JT25 RS06330
gene id: 1538553:JT25_RS06330
uniprot id: A0A126T200
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1538553:JT25 RS10295
gene id: 1538553:JT25_RS10295
uniprot id: A0A126T564
names: Similarity
messages: Belongs to the LOG family.

1538553:JT25 RS01760
gene id: 1538553:JT25_RS01760
uniprot id: A0A140E498
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS11020
gene id: 1538553:JT25_RS11020
uniprot id: A0A126T5K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1538553:JT25 RS08005
gene id: 1538553:JT25_RS08005
uniprot id: A0A126T3W1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1538553:JT25 RS07300
gene id: 1538553:JT25_RS07300
uniprot id: A0A126T2I5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1538553:JT25 RS18810
gene id: 1538553:JT25_RS18810
uniprot id: A0A126T8V3
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS18625
gene id: 1538553:JT25_RS18625
uniprot id: A0A126T8U4
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS01255
gene id: 1538553:JT25_RS01255
uniprot id: A0A140E3Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1538553:JT25 RS14545
gene id: 1538553:JT25_RS14545
uniprot id: A0A126T6I1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1538553:JT25 RS15910
gene id: 1538553:JT25_RS15910
uniprot id: A0A126T774
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1538553:JT25 RS22220
gene id: 1538553:JT25_RS22220
uniprot id: A0A140E6Z0
names: Subcellular Location Annotation
messages: Nucleus

1538553:JT25 RS21275
gene id: 1538553:JT25_RS21275
uniprot id: A0A140E6G1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1538553:JT25 RS11035
gene id: 1538553:JT25_RS11035
uniprot id: A0A126T4M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1538553:JT25 RS05870
gene id: 1538553:JT25_RS05870
uniprot id: A0A126T1R1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1538553:JT25 RS01995
gene id: 1538553:JT25_RS01995
uniprot id: A0A140E4E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS11610
gene id: 1538553:JT25_RS11610
uniprot id: A0A126T4Y2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1538553:JT25 RS06370
gene id: 1538553:JT25_RS06370
uniprot id: A0A126T204
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS19240
gene id: 1538553:JT25_RS19240
uniprot id: A0A126T947
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1538553:JT25 RS09455
gene id: 1538553:JT25_RS09455
uniprot id: A0A126T4S0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1538553:JT25 RS20010
gene id: 1538553:JT25_RS20010
uniprot id: A0A140E5S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1538553:JT25 RS11175
gene id: 1538553:JT25_RS11175
uniprot id: A0A126T4P8
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS07215
gene id: 1538553:JT25_RS07215
uniprot id: A0A126T2I2
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1538553:JT25 RS04140
gene id: 1538553:JT25_RS04140
uniprot id: A0A126T0P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1538553:JT25 RS10795
gene id: 1538553:JT25_RS10795
uniprot id: A0A126T4E9
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1538553:JT25 RS09610
gene id: 1538553:JT25_RS09610
uniprot id: A0A126T4U4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1538553:JT25 RS11870
gene id: 1538553:JT25_RS11870
uniprot id: A0A126T601
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1538553:JT25 RS17120
gene id: 1538553:JT25_RS17120
uniprot id: A0A126T8T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1538553:JT25 RS02865
gene id: 1538553:JT25_RS02865
uniprot id: A0A140E4W6
names: Similarity
messages: Belongs to the UPF0175 family.
messages: Belongs to the phD/YefM antitoxin family.

1538553:JT25 RS19835
gene id: 1538553:JT25_RS19835
uniprot id: A0A140E5N9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1538553:JT25 RS01230
gene id: 1538553:JT25_RS01230
uniprot id: A0A140E3Z3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1538553:JT25 RS21415
gene id: 1538553:JT25_RS21415
uniprot id: A0A140E6I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1538553:JT25 RS09515
gene id: 1538553:JT25_RS09515
uniprot id: A0A126T3R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS12905
gene id: 1538553:JT25_RS12905
uniprot id: A0A126T5L4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1538553:JT25 RS20745
gene id: 1538553:JT25_RS20745
uniprot id: A0A140E659
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1538553:JT25 RS16050
gene id: 1538553:JT25_RS16050
uniprot id: A0A126T7A2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1538553:JT25 RS07720
gene id: 1538553:JT25_RS07720
uniprot id: A0A126T2R7
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

1538553:JT25 RS11615
gene id: 1538553:JT25_RS11615
uniprot id: A0A126T4W0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1538553:JT25 RS22140
gene id: 1538553:JT25_RS22140
uniprot id: A0A140E6X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1538553:JT25 RS22705
gene id: 1538553:JT25_RS22705
uniprot id: A0A126T7N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1538553:JT25 RS04005
gene id: 1538553:JT25_RS04005
uniprot id: A0A140E5I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1538553:JT25 RS12235
gene id: 1538553:JT25_RS12235
uniprot id: A0A126T5B0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1538553:JT25 RS11125
gene id: 1538553:JT25_RS11125
uniprot id: A0A126T4L8
names: Similarity
messages: Belongs to the hemerythrin family.

1538553:JT25 RS07405
gene id: 1538553:JT25_RS07405
uniprot id: A0A126T2M3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1538553:JT25 RS18695
gene id: 1538553:JT25_RS18695
uniprot id: A0A126T9M0
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1538553:JT25 RS01440
gene id: 1538553:JT25_RS01440
uniprot id: A0A140E434
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1538553:JT25 RS23545
gene id: 1538553:JT25_RS23545
uniprot id: A0A140E7P8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS08865
gene id: 1538553:JT25_RS08865
uniprot id: A0A126T3F0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS14390
gene id: 1538553:JT25_RS14390
uniprot id: A0A126T6D6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1538553:JT25 RS07500
gene id: 1538553:JT25_RS07500
uniprot id: A0A126T2L7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1538553:JT25 RS13225
gene id: 1538553:JT25_RS13225
uniprot id: A0A126T5T9
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1538553:JT25 RS13090
gene id: 1538553:JT25_RS13090
uniprot id: A0A126T5P2
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1538553:JT25 RS02295
gene id: 1538553:JT25_RS02295
uniprot id: A0A140E4K4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1538553:JT25 RS22720
gene id: 1538553:JT25_RS22720
uniprot id: A0A140E790
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1538553:JT25 RS17260
gene id: 1538553:JT25_RS17260
uniprot id: A0A126T817
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1538553:JT25 RS04215
gene id: 1538553:JT25_RS04215
uniprot id: A0A126T1X7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1538553:JT25 RS00130
gene id: 1538553:JT25_RS00130
uniprot id: A0A140E3D1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1538553:JT25 RS05930
gene id: 1538553:JT25_RS05930
uniprot id: A0A126T2S5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS15130
gene id: 1538553:JT25_RS15130
uniprot id: A0A126T6T4
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1538553:JT25 RS14110
gene id: 1538553:JT25_RS14110
uniprot id: A0A126T697
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1538553:JT25 RS01375
gene id: 1538553:JT25_RS01375
uniprot id: A0A140E421
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1538553:JT25 RS10820
gene id: 1538553:JT25_RS10820
uniprot id: A0A126T5F4
names: Similarity
messages: Belongs to the AHA1 family.

1538553:JT25 RS07400
gene id: 1538553:JT25_RS07400
uniprot id: A0A126T2J6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1538553:JT25 RS07840
gene id: 1538553:JT25_RS07840
uniprot id: A0A126T2V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1538553:JT25 RS14815
gene id: 1538553:JT25_RS14815
uniprot id: A0A126T6S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1538553:JT25 RS19020
gene id: 1538553:JT25_RS19020
uniprot id: A0A126T900
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

1538553:JT25 RS10435
gene id: 1538553:JT25_RS10435
uniprot id: A0A126T4B8
names: Similarity
messages: Belongs to the UPF0102 family.

1538553:JT25 RS06580
gene id: 1538553:JT25_RS06580
uniprot id: A0A126T259
names: Similarity
messages: Belongs to the HypD family.

1538553:JT25 RS13865
gene id: 1538553:JT25_RS13865
uniprot id: A0A126T658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS20805
gene id: 1538553:JT25_RS20805
uniprot id: A0A140E671
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1538553:JT25 RS10375
gene id: 1538553:JT25_RS10375
uniprot id: A0A126T494
names: Similarity
messages: Belongs to the hemerythrin family.

1538553:JT25 RS07605
gene id: 1538553:JT25_RS07605
uniprot id: A0A126T2R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1538553:JT25 RS16150
gene id: 1538553:JT25_RS16150
uniprot id: A0A126T7C3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1538553:JT25 RS04970
gene id: 1538553:JT25_RS04970
uniprot id: A0A126T2A6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1538553:JT25 RS01020
gene id: 1538553:JT25_RS01020
uniprot id: A0A140E3V1
names: Similarity
messages: Belongs to the HSP15 family.

1538553:JT25 RS04450
gene id: 1538553:JT25_RS04450
uniprot id: A0A126T0X4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1538553:JT25 RS15890
gene id: 1538553:JT25_RS15890
uniprot id: A0A126T790
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS04315
gene id: 1538553:JT25_RS04315
uniprot id: A0A126T1Z2
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1538553:JT25 RS07270
gene id: 1538553:JT25_RS07270
uniprot id: A0A126T3I7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1538553:JT25 RS13280
gene id: 1538553:JT25_RS13280
uniprot id: A0A126T5V3
names: Similarity
messages: Belongs to the selenium-binding protein family.

1538553:JT25 RS04370
gene id: 1538553:JT25_RS04370
uniprot id: A0A126T0W6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1538553:JT25 RS19940
gene id: 1538553:JT25_RS19940
uniprot id: A0A140E5R0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1538553:JT25 RS02725
gene id: 1538553:JT25_RS02725
uniprot id: A0A140E4T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS18805
gene id: 1538553:JT25_RS18805
uniprot id: A0A126T9P4
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS08985
gene id: 1538553:JT25_RS08985
uniprot id: A0A126T3E9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1538553:JT25 RS08495
gene id: 1538553:JT25_RS08495
uniprot id: A0A126T381
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1538553:JT25 RS01090
gene id: 1538553:JT25_RS01090
uniprot id: A0A140E3W5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1538553:JT25 RS15495
gene id: 1538553:JT25_RS15495
uniprot id: A0A126T6Z5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1538553:JT25 RS17245
gene id: 1538553:JT25_RS17245
uniprot id: A0A126T7Z1
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1538553:JT25 RS11240
gene id: 1538553:JT25_RS11240
uniprot id: A0A126T4N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1538553:JT25 RS14065
gene id: 1538553:JT25_RS14065
uniprot id: A0A126T680
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1538553:JT25 RS18300
gene id: 1538553:JT25_RS18300
uniprot id: A0A126T8R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1538553:JT25 RS11050
gene id: 1538553:JT25_RS11050
uniprot id: A0A126T4N6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS04440
gene id: 1538553:JT25_RS04440
uniprot id: A0A126T0X1
names: Similarity
messages: Belongs to the YfgM family.

1538553:JT25 RS07150
gene id: 1538553:JT25_RS07150
uniprot id: A0A126T2G3
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1538553:JT25 RS17770
gene id: 1538553:JT25_RS17770
uniprot id: A0A126T8C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1538553:JT25 RS11585
gene id: 1538553:JT25_RS11585
uniprot id: A0A126T4W7
names: Similarity
messages: Belongs to the YciI family.

1538553:JT25 RS18295
gene id: 1538553:JT25_RS18295
uniprot id: A0A126T8L0
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1538553:JT25 RS21825
gene id: 1538553:JT25_RS21825
uniprot id: A0A140E6R3
names: Similarity
messages: Belongs to the transposase 8 family.

1538553:JT25 RS17350
gene id: 1538553:JT25_RS17350
uniprot id: A0A126T852
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1538553:JT25 RS06170
gene id: 1538553:JT25_RS06170
uniprot id: A0A126T1X0
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS12230
gene id: 1538553:JT25_RS12230
uniprot id: A0A126T576
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1538553:JT25 RS17250
gene id: 1538553:JT25_RS17250
uniprot id: A0A126T840
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1538553:JT25 RS11620
gene id: 1538553:JT25_RS11620
uniprot id: A0A126T5V7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1538553:JT25 RS17305
gene id: 1538553:JT25_RS17305
uniprot id: A0A126T820
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1538553:JT25 RS20630
gene id: 1538553:JT25_RS20630
uniprot id: A0A140E636
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

1538553:JT25 RS06645
gene id: 1538553:JT25_RS06645
uniprot id: A0A126T263
names: Similarity
messages: Belongs to the peptidase A31 family.

1538553:JT25 RS19215
gene id: 1538553:JT25_RS19215
uniprot id: A0A126T922
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS17085
gene id: 1538553:JT25_RS17085
uniprot id: A0A126T7W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1538553:JT25 RS14135
gene id: 1538553:JT25_RS14135
uniprot id: A0A126T693
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1538553:JT25 RS06660
gene id: 1538553:JT25_RS06660
uniprot id: A0A126T373
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1538553:JT25 RS22485
gene id: 1538553:JT25_RS22485
uniprot id: A0A140E743
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1538553:JT25 RS18205
gene id: 1538553:JT25_RS18205
uniprot id: A0A126T8H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS14300
gene id: 1538553:JT25_RS14300
uniprot id: A0A126T6D1
names: Similarity
messages: Belongs to the bacterial secretin family.

1538553:JT25 RS01225
gene id: 1538553:JT25_RS01225
uniprot id: A0A140E3Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1538553:JT25 RS22410
gene id: 1538553:JT25_RS22410
uniprot id: A0A140E728
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1538553:JT25 RS02695
gene id: 1538553:JT25_RS02695
uniprot id: A0A140E4T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1538553:JT25 RS07455
gene id: 1538553:JT25_RS07455
uniprot id: A0A126T2N4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1538553:JT25 RS08605
gene id: 1538553:JT25_RS08605
uniprot id: A0A126T3A2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1538553:JT25 RS16615
gene id: 1538553:JT25_RS16615
uniprot id: A0A126T7L1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1538553:JT25 RS02015
gene id: 1538553:JT25_RS02015
uniprot id: A0A140E4E8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1538553:JT25 RS10085
gene id: 1538553:JT25_RS10085
uniprot id: A0A126T526
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1538553:JT25 RS09860
gene id: 1538553:JT25_RS09860
uniprot id: A0A126T3X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1538553:JT25 RS13580
gene id: 1538553:JT25_RS13580
uniprot id: A0A126T605
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

1538553:JT25 RS19165
gene id: 1538553:JT25_RS19165
uniprot id: A0A126T920
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1538553:JT25 RS10280
gene id: 1538553:JT25_RS10280
uniprot id: A0A126T453
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS14115
gene id: 1538553:JT25_RS14115
uniprot id: A0A126T688
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1538553:JT25 RS08110
gene id: 1538553:JT25_RS08110
uniprot id: A0A126T303
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS23350
gene id: 1538553:JT25_RS23350
uniprot id: A0A140E7L2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1538553:JT25 RS07550
gene id: 1538553:JT25_RS07550
uniprot id: A0A126T2Q4
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1538553:JT25 RS15375
gene id: 1538553:JT25_RS15375
uniprot id: A0A126T6X8
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS22205
gene id: 1538553:JT25_RS22205
uniprot id: A0A140E6Y7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1538553:JT25 RS18225
gene id: 1538553:JT25_RS18225
uniprot id: A0A126T8J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1538553:JT25 RS07725
gene id: 1538553:JT25_RS07725
uniprot id: A0A126T2R4
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS22060
gene id: 1538553:JT25_RS22060
uniprot id: A0A140E6V9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS12260
gene id: 1538553:JT25_RS12260
uniprot id: A0A126T587
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1538553:JT25 RS23390
gene id: 1538553:JT25_RS23390
uniprot id: A0A140E7L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1538553:JT25 RS09770
gene id: 1538553:JT25_RS09770
uniprot id: A0A126T4X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1538553:JT25 RS05165
gene id: 1538553:JT25_RS05165
uniprot id: A0A126T1B8
names: Similarity
messages: Belongs to the FemABX family.

1538553:JT25 RS19775
gene id: 1538553:JT25_RS19775
uniprot id: A0A140E5M7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1538553:JT25 RS18675
gene id: 1538553:JT25_RS18675
uniprot id: A0A126T8V4
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1538553:JT25 RS15885
gene id: 1538553:JT25_RS15885
uniprot id: A0A126T7D1
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS18190
gene id: 1538553:JT25_RS18190
uniprot id: A0A126T8J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS22885
gene id: 1538553:JT25_RS22885
uniprot id: A0A140E7C3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1538553:JT25 RS17540
gene id: 1538553:JT25_RS17540
uniprot id: A0A126T864
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS04915
gene id: 1538553:JT25_RS04915
uniprot id: A0A126T176
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1538553:JT25 RS16085
gene id: 1538553:JT25_RS16085
uniprot id: A0A126T7G9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1538553:JT25 RS13980
gene id: 1538553:JT25_RS13980
uniprot id: A0A126T673
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1538553:JT25 RS15700
gene id: 1538553:JT25_RS15700
uniprot id: A0A126T816
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1538553:JT25 RS14200
gene id: 1538553:JT25_RS14200
uniprot id: A0A126T6B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1538553:JT25 RS11945
gene id: 1538553:JT25_RS11945
uniprot id: A0A126T524
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1538553:JT25 RS12705
gene id: 1538553:JT25_RS12705
uniprot id: A0A126T5H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1538553:JT25 RS14145
gene id: 1538553:JT25_RS14145
uniprot id: A0A126T6A4
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS14755
gene id: 1538553:JT25_RS14755
uniprot id: A0A126T6P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1538553:JT25 RS00340
gene id: 1538553:JT25_RS00340
uniprot id: A0A140E3H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1538553:JT25 RS18750
gene id: 1538553:JT25_RS18750
uniprot id: A0A126T8U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1538553:JT25 RS06070
gene id: 1538553:JT25_RS06070
uniprot id: A0A126T1V0
names: Similarity
messages: Belongs to the GcvT family.

1538553:JT25 RS04025
gene id: 1538553:JT25_RS04025
uniprot id: A0A140E5I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1538553:JT25 RS15205
gene id: 1538553:JT25_RS15205
uniprot id: A0A126T6Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1538553:JT25 RS05405
gene id: 1538553:JT25_RS05405
uniprot id: A0A126T1G8
names: Similarity
messages: Belongs to the RelE toxin family.

1538553:JT25 RS02375
gene id: 1538553:JT25_RS02375
uniprot id: A0A140E4M0
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1538553:JT25 RS07475
gene id: 1538553:JT25_RS07475
uniprot id: A0A126T2M8
names: Similarity
messages: Belongs to the YkuD family.

1538553:JT25 RS04485
gene id: 1538553:JT25_RS04485
uniprot id: A0A126T0Y7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS04210
gene id: 1538553:JT25_RS04210
uniprot id: A0A126T0T3
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS09365
gene id: 1538553:JT25_RS09365
uniprot id: A0A126T3N5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1538553:JT25 RS16205
gene id: 1538553:JT25_RS16205
uniprot id: A0A126T7D3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1538553:JT25 RS14370
gene id: 1538553:JT25_RS14370
uniprot id: A0A126T6G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

1538553:JT25 RS01295
gene id: 1538553:JT25_RS01295
uniprot id: A0A140E406
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS17410
gene id: 1538553:JT25_RS17410
uniprot id: A0A126T868
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1538553:JT25 RS15680
gene id: 1538553:JT25_RS15680
uniprot id: A0A126T794
names: Subcellular Location Annotation
messages: Cell inner membrane

1538553:JT25 RS15425
gene id: 1538553:JT25_RS15425
uniprot id: A0A126T6Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

1538553:JT25 RS09220
gene id: 1538553:JT25_RS09220
uniprot id: A0A126T3M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1538553:JT25 RS10430
gene id: 1538553:JT25_RS10430
uniprot id: A0A126T487
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1538553:JT25 RS12980
gene id: 1538553:JT25_RS12980
uniprot id: A0A126T5N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1538553:JT25 RS21410
gene id: 1538553:JT25_RS21410
uniprot id: A0A140E6I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1538553:JT25 RS10205
gene id: 1538553:JT25_RS10205
uniprot id: A0A126T462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1538553:JT25 RS15060
gene id: 1538553:JT25_RS15060
uniprot id: A0A126T6R9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1538553:JT25 RS12225
gene id: 1538553:JT25_RS12225
uniprot id: A0A126T584
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1538553:JT25 RS05300
gene id: 1538553:JT25_RS05300
uniprot id: A0A126T1F3
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

1538553:JT25 RS05550
gene id: 1538553:JT25_RS05550
uniprot id: A0A126T1K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1538553:JT25 RS14760
gene id: 1538553:JT25_RS14760
uniprot id: A0A126T6K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1538553:JT25 RS04435
gene id: 1538553:JT25_RS04435
uniprot id: A0A126T0X7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS01745
gene id: 1538553:JT25_RS01745
uniprot id: A0A140E495
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1538553:JT25 RS05360
gene id: 1538553:JT25_RS05360
uniprot id: A0A126T3K2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1538553:JT25 RS16875
gene id: 1538553:JT25_RS16875
uniprot id: A0A126T7R6
names: Similarity
messages: Belongs to the fabD family.

1538553:JT25 RS16695
gene id: 1538553:JT25_RS16695
uniprot id: A0A126T7N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1538553:JT25 RS10315
gene id: 1538553:JT25_RS10315
uniprot id: A0A126T484
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1538553:JT25 RS09950
gene id: 1538553:JT25_RS09950
uniprot id: A0A126T411
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS16080
gene id: 1538553:JT25_RS16080
uniprot id: A0A126T7B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1538553:JT25 RS03635
gene id: 1538553:JT25_RS03635
uniprot id: A0A140E5B2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1538553:JT25 RS17270
gene id: 1538553:JT25_RS17270
uniprot id: A0A126T8W5
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1538553:JT25 RS06850
gene id: 1538553:JT25_RS06850
uniprot id: A0A126T295
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1538553:JT25 RS06855
gene id: 1538553:JT25_RS06855
uniprot id: A0A126T2A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1538553:JT25 RS21345
gene id: 1538553:JT25_RS21345
uniprot id: A0A140E6H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1538553:JT25 RS19135
gene id: 1538553:JT25_RS19135
uniprot id: A0A126T935
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS13890
gene id: 1538553:JT25_RS13890
uniprot id: A0A126T661
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1538553:JT25 RS04625
gene id: 1538553:JT25_RS04625
uniprot id: A0A126T117
names: Similarity
messages: Belongs to the DEAD box helicase family.

1538553:JT25 RS13490
gene id: 1538553:JT25_RS13490
uniprot id: A0A126T5Y4
names: Similarity
messages: Belongs to the FwdC/FmdC family.

1538553:JT25 RS01485
gene id: 1538553:JT25_RS01485
uniprot id: A0A140E443
names: Subcellular Location Annotation
messages: Cell inner membrane

1538553:JT25 RS04250
gene id: 1538553:JT25_RS04250
uniprot id: A0A126T0T5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1538553:JT25 RS14795
gene id: 1538553:JT25_RS14795
uniprot id: A0A126T6N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1538553:JT25 RS11845
gene id: 1538553:JT25_RS11845
uniprot id: A0A126T502
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS16925
gene id: 1538553:JT25_RS16925
uniprot id: A0A126T7S6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1538553:JT25 RS02025
gene id: 1538553:JT25_RS02025
uniprot id: A0A140E4F0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1538553:JT25 RS16365
gene id: 1538553:JT25_RS16365
uniprot id: A0A126T7G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

1538553:JT25 RS07195
gene id: 1538553:JT25_RS07195
uniprot id: A0A126T2I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1538553:JT25 RS09375
gene id: 1538553:JT25_RS09375
uniprot id: A0A126T3Q5
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1538553:JT25 RS21670
gene id: 1538553:JT25_RS21670
uniprot id: A0A140E6N6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1538553:JT25 RS17870
gene id: 1538553:JT25_RS17870
uniprot id: A0A126T8E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS11630
gene id: 1538553:JT25_RS11630
uniprot id: A0A126T4X4
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1538553:JT25 RS15015
gene id: 1538553:JT25_RS15015
uniprot id: A0A126T6V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1538553:JT25 RS01570
gene id: 1538553:JT25_RS01570
uniprot id: A0A140E460
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1538553:JT25 RS07210
gene id: 1538553:JT25_RS07210
uniprot id: A0A126T2I3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1538553:JT25 RS14595
gene id: 1538553:JT25_RS14595
uniprot id: A0A126T6J3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1538553:JT25 RS15675
gene id: 1538553:JT25_RS15675
uniprot id: A0A126T737
names: Similarity
messages: Belongs to the cytochrome P450 family.

1538553:JT25 RS01370
gene id: 1538553:JT25_RS01370
uniprot id: A0A140E420
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1538553:JT25 RS17575
gene id: 1538553:JT25_RS17575
uniprot id: A0A126T855
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1538553:JT25 RS08970
gene id: 1538553:JT25_RS08970
uniprot id: A0A126T3H1
names: Similarity
messages: Belongs to the CobH/CbiC family.

1538553:JT25 RS16120
gene id: 1538553:JT25_RS16120
uniprot id: A0A126T7D0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1538553:JT25 RS19355
gene id: 1538553:JT25_RS19355
uniprot id: A0A126T966
names: Similarity
messages: Belongs to the HisA/HisF family.

1538553:JT25 RS06870
gene id: 1538553:JT25_RS06870
uniprot id: A0A126T2B8
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1538553:JT25 RS10835
gene id: 1538553:JT25_RS10835
uniprot id: A0A126T4I1
names: Similarity
messages: Belongs to the YciI family.

1538553:JT25 RS20800
gene id: 1538553:JT25_RS20800
uniprot id: A0A140E670
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1538553:JT25 RS16570
gene id: 1538553:JT25_RS16570
uniprot id: A0A126T8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1538553:JT25 RS19545
gene id: 1538553:JT25_RS19545
uniprot id: A0A126T9A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1538553:JT25 RS16770
gene id: 1538553:JT25_RS16770
uniprot id: A0A126T8L5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1538553:JT25 RS05895
gene id: 1538553:JT25_RS05895
uniprot id: A0A126T1S5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS04690
gene id: 1538553:JT25_RS04690
uniprot id: A0A126T126
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1538553:JT25 RS18540
gene id: 1538553:JT25_RS18540
uniprot id: A0A126T8Q3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1538553:JT25 RS14185
gene id: 1538553:JT25_RS14185
uniprot id: A0A126T6A5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1538553:JT25 RS11765
gene id: 1538553:JT25_RS11765
uniprot id: A0A126T4Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1538553:JT25 RS20715
gene id: 1538553:JT25_RS20715
uniprot id: A0A140E653
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1538553:JT25 RS11230
gene id: 1538553:JT25_RS11230
uniprot id: A0A126T4N9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS12250
gene id: 1538553:JT25_RS12250
uniprot id: A0A126T579
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS17215
gene id: 1538553:JT25_RS17215
uniprot id: A0A126T7Y2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1538553:JT25 RS22735
gene id: 1538553:JT25_RS22735
uniprot id: A0A140E793
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS13540
gene id: 1538553:JT25_RS13540
uniprot id: A0A126T5Z2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1538553:JT25 RS14635
gene id: 1538553:JT25_RS14635
uniprot id: A0A126T6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1538553:JT25 RS00175
gene id: 1538553:JT25_RS00175
uniprot id: A0A140E3E0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1538553:JT25 RS07755
gene id: 1538553:JT25_RS07755
uniprot id: A0A126T2T8
names: Similarity
messages: Belongs to the peptidase M16 family.

1538553:JT25 RS04090
gene id: 1538553:JT25_RS04090
uniprot id: A0A140E5J5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS17365
gene id: 1538553:JT25_RS17365
uniprot id: A0A126T833
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1538553:JT25 RS07780
gene id: 1538553:JT25_RS07780
uniprot id: A0A126T2V2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1538553:JT25 RS09705
gene id: 1538553:JT25_RS09705
uniprot id: A0A126T3U8
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS07600
gene id: 1538553:JT25_RS07600
uniprot id: A0A126T2N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1538553:JT25 RS22895
gene id: 1538553:JT25_RS22895
uniprot id: A0A140E7C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1538553:JT25 RS13430
gene id: 1538553:JT25_RS13430
uniprot id: A0A126T5X9
names: Similarity
messages: Belongs to the YggT family.

1538553:JT25 RS14205
gene id: 1538553:JT25_RS14205
uniprot id: A0A126T6C1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1538553:JT25 RS04960
gene id: 1538553:JT25_RS04960
uniprot id: A0A126T181
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

1538553:JT25 RS22185
gene id: 1538553:JT25_RS22185
uniprot id: A0A140E6Y3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS14655
gene id: 1538553:JT25_RS14655
uniprot id: A0A126T6L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1538553:JT25 RS20685
gene id: 1538553:JT25_RS20685
uniprot id: A0A140E647
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1538553:JT25 RS11045
gene id: 1538553:JT25_RS11045
uniprot id: A0A126T4K3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1538553:JT25 RS18165
gene id: 1538553:JT25_RS18165
uniprot id: A0A126T8J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS03720
gene id: 1538553:JT25_RS03720
uniprot id: A0A140E5C8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1538553:JT25 RS14040
gene id: 1538553:JT25_RS14040
uniprot id: A0A126T6A3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS07825
gene id: 1538553:JT25_RS07825
uniprot id: A0A126T2T7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1538553:JT25 RS10995
gene id: 1538553:JT25_RS10995
uniprot id: A0A126T4J4
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1538553:JT25 RS13000
gene id: 1538553:JT25_RS13000
uniprot id: A0A126T5N8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1538553:JT25 RS07335
gene id: 1538553:JT25_RS07335
uniprot id: A0A126T2I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1538553:JT25 RS15600
gene id: 1538553:JT25_RS15600
uniprot id: A0A126T7Z4
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS12395
gene id: 1538553:JT25_RS12395
uniprot id: A0A126T5C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1538553:JT25 RS11625
gene id: 1538553:JT25_RS11625
uniprot id: A0A126T4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1538553:JT25 RS17340
gene id: 1538553:JT25_RS17340
uniprot id: A0A126T822
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1538553:JT25 RS17105
gene id: 1538553:JT25_RS17105
uniprot id: A0A126T7Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1538553:JT25 RS04050
gene id: 1538553:JT25_RS04050
uniprot id: A0A140E5J2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1538553:JT25 RS19765
gene id: 1538553:JT25_RS19765
uniprot id: A0A140E5M5
names: Similarity
messages: Belongs to the glycosyltransferase 6 family.

1538553:JT25 RS17920
gene id: 1538553:JT25_RS17920
uniprot id: A0A126T8F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1538553:JT25 RS15335
gene id: 1538553:JT25_RS15335
uniprot id: A0A126T6X6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS11415
gene id: 1538553:JT25_RS11415
uniprot id: A0A126T4R5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1538553:JT25 RS08590
gene id: 1538553:JT25_RS08590
uniprot id: A0A126T390
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1538553:JT25 RS11830
gene id: 1538553:JT25_RS11830
uniprot id: A0A126T513
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1538553:JT25 RS00720
gene id: 1538553:JT25_RS00720
uniprot id: A0A140E3P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1538553:JT25 RS06785
gene id: 1538553:JT25_RS06785
uniprot id: A0A126T2A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1538553:JT25 RS21125
gene id: 1538553:JT25_RS21125
uniprot id: A0A140E6D2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1538553:JT25 RS09920
gene id: 1538553:JT25_RS09920
uniprot id: A0A126T3Y9
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1538553:JT25 RS16650
gene id: 1538553:JT25_RS16650
uniprot id: A0A126T7S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YtcA family.
messages: Membrane

1538553:JT25 RS04765
gene id: 1538553:JT25_RS04765
uniprot id: A0A126T143
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1538553:JT25 RS16345
gene id: 1538553:JT25_RS16345
uniprot id: A0A126T7G3
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1538553:JT25 RS04990
gene id: 1538553:JT25_RS04990
uniprot id: A0A126T187
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1538553:JT25 RS04320
gene id: 1538553:JT25_RS04320
uniprot id: A0A126T0V6
names: Subcellular Location Annotation
messages: Cell inner membrane

1538553:JT25 RS12710
gene id: 1538553:JT25_RS12710
uniprot id: A0A126T5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1538553:JT25 RS11595
gene id: 1538553:JT25_RS11595
uniprot id: A0A126T4U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1538553:JT25 RS18660
gene id: 1538553:JT25_RS18660
uniprot id: A0A126T8T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1538553:JT25 RS03045
gene id: 1538553:JT25_RS03045
uniprot id: A0A140E501
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS13050
gene id: 1538553:JT25_RS13050
uniprot id: A0A126T5P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1538553:JT25 RS00990
gene id: 1538553:JT25_RS00990
uniprot id: A0A140E3U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1538553:JT25 RS09225
gene id: 1538553:JT25_RS09225
uniprot id: A0A126T3L4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1538553:JT25 RS13250
gene id: 1538553:JT25_RS13250
uniprot id: A0A126T6N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1538553:JT25 RS22325
gene id: 1538553:JT25_RS22325
uniprot id: A0A140E711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1538553:JT25 RS08160
gene id: 1538553:JT25_RS08160
uniprot id: A0A126T317
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1538553:JT25 RS22370
gene id: 1538553:JT25_RS22370
uniprot id: A0A140E720
names: Similarity
messages: Belongs to the GppA/Ppx family.

1538553:JT25 RS19995
gene id: 1538553:JT25_RS19995
uniprot id: A0A140E5S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1538553:JT25 RS21705
gene id: 1538553:JT25_RS21705
uniprot id: A0A140E6P2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1538553:JT25 RS04930
gene id: 1538553:JT25_RS04930
uniprot id: A0A126T175
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1538553:JT25 RS23250
gene id: 1538553:JT25_RS23250
uniprot id: A0A140E7J3
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1538553:JT25 RS22170
gene id: 1538553:JT25_RS22170
uniprot id: A0A140E6Y1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1538553:JT25 RS20350
gene id: 1538553:JT25_RS20350
uniprot id: A0A140E5Y7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS02255
gene id: 1538553:JT25_RS02255
uniprot id: A0A140E4J6
names: Subcellular Location Annotation
messages: Cytoplasm

1538553:JT25 RS03740
gene id: 1538553:JT25_RS03740
uniprot id: A0A140E5D1
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

1538553:JT25 RS09900
gene id: 1538553:JT25_RS09900
uniprot id: A0A126T402
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS17265
gene id: 1538553:JT25_RS17265
uniprot id: A0A126T7Z3
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1538553:JT25 RS15105
gene id: 1538553:JT25_RS15105
uniprot id: A0A126T6W4
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1538553:JT25 RS15760
gene id: 1538553:JT25_RS15760
uniprot id: A0A126T748
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1538553:JT25 RS15455
gene id: 1538553:JT25_RS15455
uniprot id: A0A126T6Y8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1538553:JT25 RS13315
gene id: 1538553:JT25_RS13315
uniprot id: A0A126T5U5
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS10120
gene id: 1538553:JT25_RS10120
uniprot id: A0A126T424
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1538553:JT25 RS03980
gene id: 1538553:JT25_RS03980
uniprot id: A0A140E5H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1538553:JT25 RS05150
gene id: 1538553:JT25_RS05150
uniprot id: A0A126T1C1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1538553:JT25 RS14720
gene id: 1538553:JT25_RS14720
uniprot id: A0A126T6L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1538553:JT25 RS15490
gene id: 1538553:JT25_RS15490
uniprot id: A0A126T713
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS21240
gene id: 1538553:JT25_RS21240
uniprot id: A0A140E6F4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1538553:JT25 RS07245
gene id: 1538553:JT25_RS07245
uniprot id: A0A126T2J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1538553:JT25 RS01595
gene id: 1538553:JT25_RS01595
uniprot id: A0A140E465
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1538553:JT25 RS21435
gene id: 1538553:JT25_RS21435
uniprot id: A0A140E6J1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1538553:JT25 RS03610
gene id: 1538553:JT25_RS03610
uniprot id: A0A140E5A7
names: Function
names: Similarity
messages: Anion-transporting ATPase.
messages: Belongs to the arsA ATPase family.

1538553:JT25 RS09135
gene id: 1538553:JT25_RS09135
uniprot id: A0A126T3L0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1538553:JT25 RS06375
gene id: 1538553:JT25_RS06375
uniprot id: A0A126T218
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS01175
gene id: 1538553:JT25_RS01175
uniprot id: A0A140E3Y2
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS21460
gene id: 1538553:JT25_RS21460
uniprot id: A0A140E6J6
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS10895
gene id: 1538553:JT25_RS10895
uniprot id: A0A126T4H2
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1538553:JT25 RS07445
gene id: 1538553:JT25_RS07445
uniprot id: A0A126T2P3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1538553:JT25 RS05800
gene id: 1538553:JT25_RS05800
uniprot id: A0A126T1Q7
names: Similarity
messages: Belongs to the hemerythrin family.

1538553:JT25 RS17200
gene id: 1538553:JT25_RS17200
uniprot id: A0A126T830
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1538553:JT25 RS14950
gene id: 1538553:JT25_RS14950
uniprot id: A0A126T6N7
names: Similarity
messages: Belongs to the NodU/CmcH family.

1538553:JT25 RS01210
gene id: 1538553:JT25_RS01210
uniprot id: A0A140E3Y9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1538553:JT25 RS02150
gene id: 1538553:JT25_RS02150
uniprot id: A0A140E4H5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1538553:JT25 RS11530
gene id: 1538553:JT25_RS11530
uniprot id: A0A126T4V7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS13620
gene id: 1538553:JT25_RS13620
uniprot id: A0A126T613
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

1538553:JT25 RS21230
gene id: 1538553:JT25_RS21230
uniprot id: A0A140E6F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1538553:JT25 RS20790
gene id: 1538553:JT25_RS20790
uniprot id: A0A140E668
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1538553:JT25 RS14710
gene id: 1538553:JT25_RS14710
uniprot id: A0A126T6K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1538553:JT25 RS19960
gene id: 1538553:JT25_RS19960
uniprot id: A0A140E5R4
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1538553:JT25 RS20945
gene id: 1538553:JT25_RS20945
uniprot id: A0A140E697
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1538553:JT25 RS18130
gene id: 1538553:JT25_RS18130
uniprot id: A0A126T9B1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1538553:JT25 RS23180
gene id: 1538553:JT25_RS23180
uniprot id: A0A140E7H9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1538553:JT25 RS09645
gene id: 1538553:JT25_RS09645
uniprot id: A0A126T3W5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1538553:JT25 RS19700
gene id: 1538553:JT25_RS19700
uniprot id: A0A140E5L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1538553:JT25 RS13780
gene id: 1538553:JT25_RS13780
uniprot id: A0A126T642
names: Similarity
messages: Belongs to the thioredoxin family.

1538553:JT25 RS10125
gene id: 1538553:JT25_RS10125
uniprot id: A0A126T454
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1538553:JT25 RS09065
gene id: 1538553:JT25_RS09065
uniprot id: A0A126T3K2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1538553:JT25 RS04635
gene id: 1538553:JT25_RS04635
uniprot id: A0A126T118
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1538553:JT25 RS18290
gene id: 1538553:JT25_RS18290
uniprot id: A0A126T8L3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS07760
gene id: 1538553:JT25_RS07760
uniprot id: A0A126T2S0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1538553:JT25 RS17695
gene id: 1538553:JT25_RS17695
uniprot id: A0A126T889
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1538553:JT25 RS04530
gene id: 1538553:JT25_RS04530
uniprot id: A0A126T105
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS13905
gene id: 1538553:JT25_RS13905
uniprot id: A0A126T641
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1538553:JT25 RS02495
gene id: 1538553:JT25_RS02495
uniprot id: A0A140E4P2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1538553:JT25 RS07345
gene id: 1538553:JT25_RS07345
uniprot id: A0A126T2I7
names: Similarity
messages: Belongs to the GSP E family.

1538553:JT25 RS12680
gene id: 1538553:JT25_RS12680
uniprot id: A0A126T5H4
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1538553:JT25 RS14325
gene id: 1538553:JT25_RS14325
uniprot id: A0A126T6D3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1538553:JT25 RS13060
gene id: 1538553:JT25_RS13060
uniprot id: A0A126T5P7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1538553:JT25 RS20000
gene id: 1538553:JT25_RS20000
uniprot id: A0A140E5S2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS22970
gene id: 1538553:JT25_RS22970
uniprot id: A0A140E7D9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS00370
gene id: 1538553:JT25_RS00370
uniprot id: A0A140E3H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1538553:JT25 RS09390
gene id: 1538553:JT25_RS09390
uniprot id: A0A126T3N9
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS23595
gene id: 1538553:JT25_RS23595
uniprot id: A0A126T3H1
names: Similarity
messages: Belongs to the CobH/CbiC family.

1538553:JT25 RS20925
gene id: 1538553:JT25_RS20925
uniprot id: A0A140E693
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1538553:JT25 RS01215
gene id: 1538553:JT25_RS01215
uniprot id: A0A140E3Z0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1538553:JT25 RS07470
gene id: 1538553:JT25_RS07470
uniprot id: A0A126T2N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1538553:JT25 RS02745
gene id: 1538553:JT25_RS02745
uniprot id: A0A140E4U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS00770
gene id: 1538553:JT25_RS00770
uniprot id: A0A140E3Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1538553:JT25 RS13555
gene id: 1538553:JT25_RS13555
uniprot id: A0A126T5Z6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS06345
gene id: 1538553:JT25_RS06345
uniprot id: A0A126T201
names: Similarity
messages: Belongs to the peptidase M24B family.

1538553:JT25 RS17030
gene id: 1538553:JT25_RS17030
uniprot id: A0A126T7W8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1538553:JT25 RS15590
gene id: 1538553:JT25_RS15590
uniprot id: A0A126T734
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1538553:JT25 RS15865
gene id: 1538553:JT25_RS15865
uniprot id: A0A126T786
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1538553:JT25 RS11645
gene id: 1538553:JT25_RS11645
uniprot id: A0A126T4V5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1538553:JT25 RS03235
gene id: 1538553:JT25_RS03235
uniprot id: A0A140E537
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1538553:JT25 RS06910
gene id: 1538553:JT25_RS06910
uniprot id: A0A126T2B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1538553:JT25 RS23360
gene id: 1538553:JT25_RS23360
uniprot id: A0A140E7L4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1538553:JT25 RS04660
gene id: 1538553:JT25_RS04660
uniprot id: A0A126T119
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1538553:JT25 RS15900
gene id: 1538553:JT25_RS15900
uniprot id: A0A126T775
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1538553:JT25 RS05310
gene id: 1538553:JT25_RS05310
uniprot id: A0A126T1F0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1538553:JT25 RS12750
gene id: 1538553:JT25_RS12750
uniprot id: A0A126T5I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1538553:JT25 RS07620
gene id: 1538553:JT25_RS07620
uniprot id: A0A126T2Q0
names: Similarity
messages: Belongs to the peptidase M1 family.

1538553:JT25 RS02720
gene id: 1538553:JT25_RS02720
uniprot id: A0A140E4T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS13830
gene id: 1538553:JT25_RS13830
uniprot id: A0A126T652
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1538553:JT25 RS04455
gene id: 1538553:JT25_RS04455
uniprot id: A0A126T0Y2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1538553:JT25 RS06595
gene id: 1538553:JT25_RS06595
uniprot id: A0A126T253
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1538553:JT25 RS14695
gene id: 1538553:JT25_RS14695
uniprot id: A0A126T6L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1538553:JT25 RS13070
gene id: 1538553:JT25_RS13070
uniprot id: A0A126T5N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1538553:JT25 RS19945
gene id: 1538553:JT25_RS19945
uniprot id: A0A140E5R1
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

1538553:JT25 RS14055
gene id: 1538553:JT25_RS14055
uniprot id: A0A126T676
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1538553:JT25 RS14105
gene id: 1538553:JT25_RS14105
uniprot id: A0A126T692
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1538553:JT25 RS18845
gene id: 1538553:JT25_RS18845
uniprot id: A0A126T8Y0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1538553:JT25 RS23040
gene id: 1538553:JT25_RS23040
uniprot id: A0A140E7F2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1538553:JT25 RS17865
gene id: 1538553:JT25_RS17865
uniprot id: A0A126T8D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1538553:JT25 RS17775
gene id: 1538553:JT25_RS17775
uniprot id: A0A126T896
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS08300
gene id: 1538553:JT25_RS08300
uniprot id: A0A126T333
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1538553:JT25 RS04655
gene id: 1538553:JT25_RS04655
uniprot id: A0A126T123
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1538553:JT25 RS06590
gene id: 1538553:JT25_RS06590
uniprot id: A0A126T246
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1538553:JT25 RS10025
gene id: 1538553:JT25_RS10025
uniprot id: A0A126T436
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1538553:JT25 RS00330
gene id: 1538553:JT25_RS00330
uniprot id: A0A140E3H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1538553:JT25 RS15500
gene id: 1538553:JT25_RS15500
uniprot id: A0A126T7X6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1538553:JT25 RS03590
gene id: 1538553:JT25_RS03590
uniprot id: A0A140E5A3
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1538553:JT25 RS07085
gene id: 1538553:JT25_RS07085
uniprot id: A0A126T2H7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1538553:JT25 RS08015
gene id: 1538553:JT25_RS08015
uniprot id: A0A126T2X6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1538553:JT25 RS08880
gene id: 1538553:JT25_RS08880
uniprot id: A0A126T3G5
names: Subcellular Location Annotation
messages: Membrane

1538553:JT25 RS17020
gene id: 1538553:JT25_RS17020
uniprot id: A0A126T8R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1538553:JT25 RS02250
gene id: 1538553:JT25_RS02250
uniprot id: A0A140E4J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1538553:JT25 RS09035
gene id: 1538553:JT25_RS09035
uniprot id: A0A126T3F7
names: Similarity
messages: Belongs to the PhzF family.

1538553:JT25 RS09240
gene id: 1538553:JT25_RS09240
uniprot id: A0A126T3K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1538553:JT25 RS19510
gene id: 1538553:JT25_RS19510
uniprot id: A0A126T9D4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1538553:JT25 RS14865
gene id: 1538553:JT25_RS14865
uniprot id: A0A126T6T3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1538553:JT25 RS05740
gene id: 1538553:JT25_RS05740
uniprot id: A0A126T1N5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1538553:JT25 RS13740
gene id: 1538553:JT25_RS13740
uniprot id: A0A126T637
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1538553:JT25 RS17040
gene id: 1538553:JT25_RS17040
uniprot id: A0A126T7Z0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1538553:JT25 RS17395
gene id: 1538553:JT25_RS17395
uniprot id: A0A126T829
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1538553:JT25 RS17675
gene id: 1538553:JT25_RS17675
uniprot id: A0A126T878
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1538553:JT25 RS05060
gene id: 1538553:JT25_RS05060
uniprot id: A0A126T194
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1538553:JT25 RS08785
gene id: 1538553:JT25_RS08785
uniprot id: A0A126T3C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1538553:JT25 RS10090
gene id: 1538553:JT25_RS10090
uniprot id: A0A126T418
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1538553:JT25 RS01910
gene id: 1538553:JT25_RS01910
uniprot id: A0A140E4C7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1538553:JT25 RS14610
gene id: 1538553:JT25_RS14610
uniprot id: A0A126T7G2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1538553:JT25 RS11040
gene id: 1538553:JT25_RS11040
uniprot id: A0A126T4M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1538553:JT25 RS20795
gene id: 1538553:JT25_RS20795
uniprot id: A0A140E669
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1538553:JT25 RS04125
gene id: 1538553:JT25_RS04125
uniprot id: A0A126T0Q0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1538553:JT25 RS23175
gene id: 1538553:JT25_RS23175
uniprot id: A0A140E7H8
names: Similarity
messages: Belongs to the IucA/IucC family.

1538553:JT25 RS04740
gene id: 1538553:JT25_RS04740
uniprot id: A0A126T137
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1538553:JT25 RS08710
gene id: 1538553:JT25_RS08710
uniprot id: A0A126T3C0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1538553:JT25 RS06715
gene id: 1538553:JT25_RS06715
uniprot id: A0A126T274
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1538553:JT25 RS20440
gene id: 1538553:JT25_RS20440
uniprot id: A0A140E604
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1538553:JT25 RS02070
gene id: 1538553:JT25_RS02070
uniprot id: A0A140E4F9
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

1538553:JT25 RS19460
gene id: 1538553:JT25_RS19460
uniprot id: A0A126T9C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1538553:JT25 RS19500
gene id: 1538553:JT25_RS19500
uniprot id: A0A126T987
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1538553:JT25 RS00930
gene id: 1538553:JT25_RS00930
uniprot id: A0A140E3T3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1538553:JT25 RS01365
gene id: 1538553:JT25_RS01365
uniprot id: A0A140E419
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.