1497:CLFO RS17615
gene id: 1497:CLFO_RS17615
uniprot id: A0A1D9FHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1497:CLFO RS12550
gene id: 1497:CLFO_RS12550
uniprot id: A0A1D9FQD2
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS20875
gene id: 1497:CLFO_RS20875
uniprot id: A0A1D9FIV5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1497:CLFO RS01750
gene id: 1497:CLFO_RS01750
uniprot id: A0A1D9FKI2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1497:CLFO RS20720
gene id: 1497:CLFO_RS20720
uniprot id: A0A1D9FIP3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1497:CLFO RS07590
gene id: 1497:CLFO_RS07590
uniprot id: A0A1D9FNE3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1497:CLFO RS07245
gene id: 1497:CLFO_RS07245
uniprot id: A0A1D9FMX0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS11505
gene id: 1497:CLFO_RS11505
uniprot id: A0A1D9FPS6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1497:CLFO RS04550
gene id: 1497:CLFO_RS04550
uniprot id: A0A1D9FLD2
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1497:CLFO RS17735
gene id: 1497:CLFO_RS17735
uniprot id: A0A1D9FI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1497:CLFO RS05325
gene id: 1497:CLFO_RS05325
uniprot id: A0A1D9FLY6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1497:CLFO RS05430
gene id: 1497:CLFO_RS05430
uniprot id: A0A1D9FMF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1497:CLFO RS19300
gene id: 1497:CLFO_RS19300
uniprot id: A0A1D9FI06
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1497:CLFO RS15335
gene id: 1497:CLFO_RS15335
uniprot id: A0A1D9FRR7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS05560
gene id: 1497:CLFO_RS05560
uniprot id: A0A1D9FM98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1497:CLFO RS19530
gene id: 1497:CLFO_RS19530
uniprot id: A0A1D9FIV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1497:CLFO RS04225
gene id: 1497:CLFO_RS04225
uniprot id: A0A1D9FL93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1497:CLFO RS01780
gene id: 1497:CLFO_RS01780
uniprot id: A0A1D9FKN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1497:CLFO RS11025
gene id: 1497:CLFO_RS11025
uniprot id: A0A1D9FQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1497:CLFO RS10295
gene id: 1497:CLFO_RS10295
uniprot id: A0A1D9FP60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1497:CLFO RS11135
gene id: 1497:CLFO_RS11135
uniprot id: A0A1D9FPL9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1497:CLFO RS12535
gene id: 1497:CLFO_RS12535
uniprot id: A0A1D9FQL7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

1497:CLFO RS03310
gene id: 1497:CLFO_RS03310
uniprot id: A0A1D9FL18
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1497:CLFO RS15845
gene id: 1497:CLFO_RS15845
uniprot id: A0A1D9FS35
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS13805
gene id: 1497:CLFO_RS13805
uniprot id: A0A1D9FSX6
names: Similarity
messages: Belongs to the NadC/ModD family.

1497:CLFO RS01360
gene id: 1497:CLFO_RS01360
uniprot id: A0A1D9FJY0
names: Similarity
messages: Belongs to the bacterial flagellin family.

1497:CLFO RS07145
gene id: 1497:CLFO_RS07145
uniprot id: A0A1D9FMR7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1497:CLFO RS18075
gene id: 1497:CLFO_RS18075
uniprot id: A0A1D9FHJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1497:CLFO RS01190
gene id: 1497:CLFO_RS01190
uniprot id: A0A1D9FJY2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1497:CLFO RS01575
gene id: 1497:CLFO_RS01575
uniprot id: A0A1D9FK53
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1497:CLFO RS19975
gene id: 1497:CLFO_RS19975
uniprot id: A0A1D9FII8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1497:CLFO RS10150
gene id: 1497:CLFO_RS10150
uniprot id: A0A1D9FP63
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS16000
gene id: 1497:CLFO_RS16000
uniprot id: A0A1D9FGJ3
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS09035
gene id: 1497:CLFO_RS09035
uniprot id: A0A1D9FNI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1497:CLFO RS06365
gene id: 1497:CLFO_RS06365
uniprot id: A0A1D9FMR0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1497:CLFO RS15290
gene id: 1497:CLFO_RS15290
uniprot id: A0A1D9FSC4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1497:CLFO RS09510
gene id: 1497:CLFO_RS09510
uniprot id: A0A1D9FP79
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS05785
gene id: 1497:CLFO_RS05785
uniprot id: A0A1D9FM06
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS11210
gene id: 1497:CLFO_RS11210
uniprot id: A0A1D9FPR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1497:CLFO RS10670
gene id: 1497:CLFO_RS10670
uniprot id: A0A1D9FPD5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1497:CLFO RS10410
gene id: 1497:CLFO_RS10410
uniprot id: A0A1D9FP74
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1497:CLFO RS03890
gene id: 1497:CLFO_RS03890
uniprot id: A0A1D9FL25
names: Function
messages: Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.

1497:CLFO RS18355
gene id: 1497:CLFO_RS18355
uniprot id: A0A1D9FHW7
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1497:CLFO RS20640
gene id: 1497:CLFO_RS20640
uniprot id: A0A1D9FIR2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1497:CLFO RS01370
gene id: 1497:CLFO_RS01370
uniprot id: A0A1D9FKC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1497:CLFO RS04025
gene id: 1497:CLFO_RS04025
uniprot id: A0A1D9FLF5
names: Similarity
messages: Belongs to the glutamate synthase family.

1497:CLFO RS05620
gene id: 1497:CLFO_RS05620
uniprot id: A0A1D9FLX5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1497:CLFO RS15830
gene id: 1497:CLFO_RS15830
uniprot id: A0A1D9FS90
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1497:CLFO RS04315
gene id: 1497:CLFO_RS04315
uniprot id: A0A1D9FLA5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1497:CLFO RS05295
gene id: 1497:CLFO_RS05295
uniprot id: A0A1D9FLR6
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

1497:CLFO RS01940
gene id: 1497:CLFO_RS01940
uniprot id: A0A1D9FKR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1497:CLFO RS02185
gene id: 1497:CLFO_RS02185
uniprot id: A0A1D9FKR4
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1497:CLFO RS19830
gene id: 1497:CLFO_RS19830
uniprot id: A0A1D9FI87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1497:CLFO RS18600
gene id: 1497:CLFO_RS18600
uniprot id: A0A1D9FHS2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS08430
gene id: 1497:CLFO_RS08430
uniprot id: A0A1D9FSV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1497:CLFO RS13650
gene id: 1497:CLFO_RS13650
uniprot id: A0A1D9FR57
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

1497:CLFO RS01220
gene id: 1497:CLFO_RS01220
uniprot id: A0A1D9FJN1
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

1497:CLFO RS08630
gene id: 1497:CLFO_RS08630
uniprot id: A0A1D9FNI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1497:CLFO RS05485
gene id: 1497:CLFO_RS05485
uniprot id: A0A1D9FLU0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS18450
gene id: 1497:CLFO_RS18450
uniprot id: A0A1D9FHR4
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

1497:CLFO RS16870
gene id: 1497:CLFO_RS16870
uniprot id: A0A1D9FH01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1497:CLFO RS15910
gene id: 1497:CLFO_RS15910
uniprot id: A0A1D9FGE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS08605
gene id: 1497:CLFO_RS08605
uniprot id: A0A1D9FNC0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1497:CLFO RS06960
gene id: 1497:CLFO_RS06960
uniprot id: A0A1D9FMH4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1497:CLFO RS22600
gene id: 1497:CLFO_RS22600
uniprot id: A0A1D9FP11
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1497:CLFO RS18445
gene id: 1497:CLFO_RS18445
uniprot id: A0A1D9FIH2
names: Similarity
messages: Belongs to the class-I fumarase family.

1497:CLFO RS20070
gene id: 1497:CLFO_RS20070
uniprot id: A0A1D9FIC6
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1497:CLFO RS20975
gene id: 1497:CLFO_RS20975
uniprot id: A0A1D9FJL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS19880
gene id: 1497:CLFO_RS19880
uniprot id: A0A1D9FIB8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1497:CLFO RS16510
gene id: 1497:CLFO_RS16510
uniprot id: A0A1D9FHC1
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1497:CLFO RS13580
gene id: 1497:CLFO_RS13580
uniprot id: A0A1D9FQU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1497:CLFO RS06595
gene id: 1497:CLFO_RS06595
uniprot id: A0A1D9FMH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1497:CLFO RS13705
gene id: 1497:CLFO_RS13705
uniprot id: A0A1D9FR68
names: Similarity
messages: Belongs to the EamA transporter family.

1497:CLFO RS16600
gene id: 1497:CLFO_RS16600
uniprot id: A0A1D9FH43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS18035
gene id: 1497:CLFO_RS18035
uniprot id: A0A1D9FI47
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1497:CLFO RS02810
gene id: 1497:CLFO_RS02810
uniprot id: A0A1D9FKI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1497:CLFO RS19580
gene id: 1497:CLFO_RS19580
uniprot id: A0A1D9FIW5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1497:CLFO RS03790
gene id: 1497:CLFO_RS03790
uniprot id: A0A1D9FKZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS19885
gene id: 1497:CLFO_RS19885
uniprot id: A0A1D9FI94
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

1497:CLFO RS11285
gene id: 1497:CLFO_RS11285
uniprot id: A0A1D9FPQ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1497:CLFO RS16180
gene id: 1497:CLFO_RS16180
uniprot id: A0A1D9FGY8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1497:CLFO RS21435
gene id: 1497:CLFO_RS21435
uniprot id: A0A1D9FJP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1497:CLFO RS16025
gene id: 1497:CLFO_RS16025
uniprot id: A0A1D9FH38
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1497:CLFO RS12235
gene id: 1497:CLFO_RS12235
uniprot id: A0A1D9FQB8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1497:CLFO RS18350
gene id: 1497:CLFO_RS18350
uniprot id: A0A1D9FI05
names: Similarity
messages: Belongs to the PRORSD1 family.

1497:CLFO RS01315
gene id: 1497:CLFO_RS01315
uniprot id: A0A1D9FKB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1497:CLFO RS19525
gene id: 1497:CLFO_RS19525
uniprot id: A0A1D9FI26
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1497:CLFO RS00505
gene id: 1497:CLFO_RS00505
uniprot id: A0A1D9FJA8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1497:CLFO RS03935
gene id: 1497:CLFO_RS03935
uniprot id: A0A1D9FL36
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1497:CLFO RS00575
gene id: 1497:CLFO_RS00575
uniprot id: A0A1D9FJB6
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS20120
gene id: 1497:CLFO_RS20120
uniprot id: A0A1D9FID6
names: Similarity
messages: Belongs to the GerABKA family.

1497:CLFO RS20080
gene id: 1497:CLFO_RS20080
uniprot id: A0A1D9FIK8
names: Similarity
messages: Belongs to the peptidase S58 family.

1497:CLFO RS02000
gene id: 1497:CLFO_RS02000
uniprot id: A0A1D9FK16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tonsoku family.
messages: Chromosome

1497:CLFO RS13975
gene id: 1497:CLFO_RS13975
uniprot id: A0A1D9FRA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS13205
gene id: 1497:CLFO_RS13205
uniprot id: A0A1D9FQT4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1497:CLFO RS07930
gene id: 1497:CLFO_RS07930
uniprot id: A0A1D9FNE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1497:CLFO RS00875
gene id: 1497:CLFO_RS00875
uniprot id: A0A1D9FJJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1497:CLFO RS09700
gene id: 1497:CLFO_RS09700
uniprot id: A0A1D9FNU3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1497:CLFO RS00695
gene id: 1497:CLFO_RS00695
uniprot id: A0A1D9FK66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1497:CLFO RS16035
gene id: 1497:CLFO_RS16035
uniprot id: A0A1D9FGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS05225
gene id: 1497:CLFO_RS05225
uniprot id: A0A1D9FLW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1497:CLFO RS19805
gene id: 1497:CLFO_RS19805
uniprot id: A0A1D9FIW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1497:CLFO RS19960
gene id: 1497:CLFO_RS19960
uniprot id: A0A1D9FJ38
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS06455
gene id: 1497:CLFO_RS06455
uniprot id: A0A1D9FM82
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1497:CLFO RS16475
gene id: 1497:CLFO_RS16475
uniprot id: A0A1D9FGS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS20860
gene id: 1497:CLFO_RS20860
uniprot id: A0A1D9FJ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1497:CLFO RS10685
gene id: 1497:CLFO_RS10685
uniprot id: A0A1D9FPG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1497:CLFO RS08985
gene id: 1497:CLFO_RS08985
uniprot id: A0A1D9FP05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS18405
gene id: 1497:CLFO_RS18405
uniprot id: A0A1D9FHX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

1497:CLFO RS11945
gene id: 1497:CLFO_RS11945
uniprot id: A0A1D9FQJ6
names: Similarity
messages: Belongs to the cytochrome c-552 family.

1497:CLFO RS07560
gene id: 1497:CLFO_RS07560
uniprot id: A0A1D9FNA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1497:CLFO RS03355
gene id: 1497:CLFO_RS03355
uniprot id: A0A1D9FLH0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS21425
gene id: 1497:CLFO_RS21425
uniprot id: A0A1D9FJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1497:CLFO RS08325
gene id: 1497:CLFO_RS08325
uniprot id: A0A1D9FSM3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS03635
gene id: 1497:CLFO_RS03635
uniprot id: A0A1D9FKX2
names: Similarity
messages: Belongs to the peptidase S8 family.

1497:CLFO RS13195
gene id: 1497:CLFO_RS13195
uniprot id: A0A1D9FQY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1497:CLFO RS18420
gene id: 1497:CLFO_RS18420
uniprot id: A0A1D9FI41
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

1497:CLFO RS05495
gene id: 1497:CLFO_RS05495
uniprot id: A0A1D9FM15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1497:CLFO RS06920
gene id: 1497:CLFO_RS06920
uniprot id: A0A1D9FMQ8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1497:CLFO RS03675
gene id: 1497:CLFO_RS03675
uniprot id: A0A1D9FKZ5
names: Similarity
messages: Belongs to the P(II) protein family.

1497:CLFO RS14470
gene id: 1497:CLFO_RS14470
uniprot id: A0A1D9FRE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1497:CLFO RS09465
gene id: 1497:CLFO_RS09465
uniprot id: A0A1D9FNQ6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS00890
gene id: 1497:CLFO_RS00890
uniprot id: A0A1D9FJH2
names: Similarity
messages: Belongs to the FBPase class 2 family.

1497:CLFO RS11495
gene id: 1497:CLFO_RS11495
uniprot id: A0A1D9FPT8
names: Similarity
messages: Belongs to the YggT family.

1497:CLFO RS04585
gene id: 1497:CLFO_RS04585
uniprot id: A0A1D9FLK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS03765
gene id: 1497:CLFO_RS03765
uniprot id: A0A1D9FL03
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1497:CLFO RS02020
gene id: 1497:CLFO_RS02020
uniprot id: A0A1D9FSL0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1497:CLFO RS08600
gene id: 1497:CLFO_RS08600
uniprot id: A0A1D9FNA8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1497:CLFO RS05565
gene id: 1497:CLFO_RS05565
uniprot id: A0A1D9FLX7
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1497:CLFO RS17610
gene id: 1497:CLFO_RS17610
uniprot id: A0A1D9FH89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1497:CLFO RS12970
gene id: 1497:CLFO_RS12970
uniprot id: A0A1D9FQT5
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1497:CLFO RS14780
gene id: 1497:CLFO_RS14780
uniprot id: A0A1D9FRR2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS11960
gene id: 1497:CLFO_RS11960
uniprot id: A0A1D9FQ92
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1497:CLFO RS14895
gene id: 1497:CLFO_RS14895
uniprot id: A0A1D9FRJ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1497:CLFO RS03850
gene id: 1497:CLFO_RS03850
uniprot id: A0A1D9FL68
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1497:CLFO RS16420
gene id: 1497:CLFO_RS16420
uniprot id: A0A1D9FSA3
names: Similarity
messages: Belongs to the threonine synthase family.

1497:CLFO RS20940
gene id: 1497:CLFO_RS20940
uniprot id: A0A1D9FIW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1497:CLFO RS05755
gene id: 1497:CLFO_RS05755
uniprot id: A0A1D9FMA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1497:CLFO RS21405
gene id: 1497:CLFO_RS21405
uniprot id: A0A1D9FJ40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1497:CLFO RS11605
gene id: 1497:CLFO_RS11605
uniprot id: A0A1D9FPV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1497:CLFO RS19560
gene id: 1497:CLFO_RS19560
uniprot id: A0A1D9FI68
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1497:CLFO RS14505
gene id: 1497:CLFO_RS14505
uniprot id: A0A1D9FRC6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS11330
gene id: 1497:CLFO_RS11330
uniprot id: A0A1D9FPQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1497:CLFO RS14120
gene id: 1497:CLFO_RS14120
uniprot id: A0A1D9FR50
names: Similarity
messages: Belongs to the AOR/FOR family.

1497:CLFO RS19760
gene id: 1497:CLFO_RS19760
uniprot id: A0A1D9FIL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1497:CLFO RS11075
gene id: 1497:CLFO_RS11075
uniprot id: A0A1D9FQ34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1497:CLFO RS05715
gene id: 1497:CLFO_RS05715
uniprot id: A0A1D9FMC5
names: Function
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1497:CLFO RS07935
gene id: 1497:CLFO_RS07935
uniprot id: A0A1D9FSV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS12310
gene id: 1497:CLFO_RS12310
uniprot id: A0A1D9FQI5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS11460
gene id: 1497:CLFO_RS11460
uniprot id: A0A1D9FQA5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1497:CLFO RS07260
gene id: 1497:CLFO_RS07260
uniprot id: A0A1D9FN26
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS00435
gene id: 1497:CLFO_RS00435
uniprot id: A0A1D9FJL8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS01935
gene id: 1497:CLFO_RS01935
uniprot id: A0A1D9FK20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1497:CLFO RS19790
gene id: 1497:CLFO_RS19790
uniprot id: A0A1D9FI76
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

1497:CLFO RS10950
gene id: 1497:CLFO_RS10950
uniprot id: A0A1D9FPI3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS14700
gene id: 1497:CLFO_RS14700
uniprot id: A0A1D9FRG6
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1497:CLFO RS10665
gene id: 1497:CLFO_RS10665
uniprot id: A0A1D9FPD9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1497:CLFO RS15115
gene id: 1497:CLFO_RS15115
uniprot id: A0A1D9FRN2
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS06075
gene id: 1497:CLFO_RS06075
uniprot id: A0A1D9FMD2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS07045
gene id: 1497:CLFO_RS07045
uniprot id: A0A1D9FMJ3
names: Similarity
messages: Belongs to the PRORSD1 family.

1497:CLFO RS11165
gene id: 1497:CLFO_RS11165
uniprot id: A0A1D9FPM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1497:CLFO RS01840
gene id: 1497:CLFO_RS01840
uniprot id: A0A1D9FKA3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1497:CLFO RS01330
gene id: 1497:CLFO_RS01330
uniprot id: A0A1D9FJP9
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1497:CLFO RS11315
gene id: 1497:CLFO_RS11315
uniprot id: A0A1D9FPR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

1497:CLFO RS16700
gene id: 1497:CLFO_RS16700
uniprot id: A0A1D9FHK1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1497:CLFO RS14910
gene id: 1497:CLFO_RS14910
uniprot id: A0A1D9FRT0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1497:CLFO RS18265
gene id: 1497:CLFO_RS18265
uniprot id: A0A1D9FI12
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1497:CLFO RS00750
gene id: 1497:CLFO_RS00750
uniprot id: A0A1D9FSA7
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1497:CLFO RS05395
gene id: 1497:CLFO_RS05395
uniprot id: A0A1D9FLT6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1497:CLFO RS15935
gene id: 1497:CLFO_RS15935
uniprot id: A0A1D9FGT5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1497:CLFO RS17820
gene id: 1497:CLFO_RS17820
uniprot id: A0A1D9FI01
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1497:CLFO RS02805
gene id: 1497:CLFO_RS02805
uniprot id: A0A1D9FL69
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS15170
gene id: 1497:CLFO_RS15170
uniprot id: A0A1D9FS98
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1497:CLFO RS08480
gene id: 1497:CLFO_RS08480
uniprot id: A0A1D9FNS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1497:CLFO RS07035
gene id: 1497:CLFO_RS07035
uniprot id: A0A1D9FN33
names: Subcellular Location Annotation
messages: Cytoplasm

1497:CLFO RS19645
gene id: 1497:CLFO_RS19645
uniprot id: A0A1D9FID0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1497:CLFO RS09185
gene id: 1497:CLFO_RS09185
uniprot id: A0A1D9FP38
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

1497:CLFO RS17930
gene id: 1497:CLFO_RS17930
uniprot id: A0A1D9FHU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

1497:CLFO RS14745
gene id: 1497:CLFO_RS14745
uniprot id: A0A1D9FRJ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1497:CLFO RS04215
gene id: 1497:CLFO_RS04215
uniprot id: A0A1D9FL85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1497:CLFO RS03875
gene id: 1497:CLFO_RS03875
uniprot id: A0A1D9FL11
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS19770
gene id: 1497:CLFO_RS19770
uniprot id: A0A1D9FI74
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1497:CLFO RS17705
gene id: 1497:CLFO_RS17705
uniprot id: A0A1D9FHF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1497:CLFO RS14730
gene id: 1497:CLFO_RS14730
uniprot id: A0A1D9FRQ3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1497:CLFO RS11435
gene id: 1497:CLFO_RS11435
uniprot id: A0A1D9FPV9
names: Similarity
messages: Belongs to the RemA family.

1497:CLFO RS05120
gene id: 1497:CLFO_RS05120
uniprot id: A0A1D9FM99
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1497:CLFO RS13725
gene id: 1497:CLFO_RS13725
uniprot id: A0A1D9FQX2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1497:CLFO RS04525
gene id: 1497:CLFO_RS04525
uniprot id: A0A1D9FLN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS00105
gene id: 1497:CLFO_RS00105
uniprot id: A0A1D9FJ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1497:CLFO RS07565
gene id: 1497:CLFO_RS07565
uniprot id: A0A1D9FMT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1497:CLFO RS05220
gene id: 1497:CLFO_RS05220
uniprot id: A0A1D9FM03
names: Similarity
messages: Belongs to the peptidase S16 family.

1497:CLFO RS21010
gene id: 1497:CLFO_RS21010
uniprot id: A0A1D9FIU9
names: Similarity
messages: Belongs to the peptidase S8 family.

1497:CLFO RS20295
gene id: 1497:CLFO_RS20295
uniprot id: A0A1D9FIG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1497:CLFO RS12170
gene id: 1497:CLFO_RS12170
uniprot id: A0A1D9FNE3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1497:CLFO RS09585
gene id: 1497:CLFO_RS09585
uniprot id: A0A1D9FSX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1497:CLFO RS02865
gene id: 1497:CLFO_RS02865
uniprot id: A0A1D9FKI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1497:CLFO RS05020
gene id: 1497:CLFO_RS05020
uniprot id: A0A1D9FLM3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS07900
gene id: 1497:CLFO_RS07900
uniprot id: A0A1D9FNB0
names: Similarity
messages: Belongs to the asparaginase 1 family.

1497:CLFO RS19550
gene id: 1497:CLFO_RS19550
uniprot id: A0A1D9FIR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1497:CLFO RS14295
gene id: 1497:CLFO_RS14295
uniprot id: A0A1D9FRT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1497:CLFO RS20065
gene id: 1497:CLFO_RS20065
uniprot id: A0A1D9FJ59
names: Similarity
messages: Belongs to the GerABKA family.

1497:CLFO RS11980
gene id: 1497:CLFO_RS11980
uniprot id: A0A1D9FQ22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1497:CLFO RS12910
gene id: 1497:CLFO_RS12910
uniprot id: A0A1D9FQN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS18610
gene id: 1497:CLFO_RS18610
uniprot id: A0A1D9FHT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1497:CLFO RS12985
gene id: 1497:CLFO_RS12985
uniprot id: A0A1D9FQP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS05140
gene id: 1497:CLFO_RS05140
uniprot id: A0A1D9FLR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS03905
gene id: 1497:CLFO_RS03905
uniprot id: A0A1D9FSQ8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1497:CLFO RS14900
gene id: 1497:CLFO_RS14900
uniprot id: A0A1D9FRM5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1497:CLFO RS15570
gene id: 1497:CLFO_RS15570
uniprot id: A0A1D9FRY5
names: Similarity
messages: Belongs to the UPF0229 family.

1497:CLFO RS13855
gene id: 1497:CLFO_RS13855
uniprot id: A0A1D9FRK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1497:CLFO RS02840
gene id: 1497:CLFO_RS02840
uniprot id: A0A1D9FKI3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1497:CLFO RS10050
gene id: 1497:CLFO_RS10050
uniprot id: A0A1D9FP03
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1497:CLFO RS18245
gene id: 1497:CLFO_RS18245
uniprot id: A0A1D9FHY7
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1497:CLFO RS00585
gene id: 1497:CLFO_RS00585
uniprot id: A0A1D9FK44
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1497:CLFO RS13425
gene id: 1497:CLFO_RS13425
uniprot id: A0A1D9FQR1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS05230
gene id: 1497:CLFO_RS05230
uniprot id: A0A1D9FMB3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1497:CLFO RS11455
gene id: 1497:CLFO_RS11455
uniprot id: A0A1D9FPR9
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1497:CLFO RS09310
gene id: 1497:CLFO_RS09310
uniprot id: A0A1D9FSQ4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1497:CLFO RS08235
gene id: 1497:CLFO_RS08235
uniprot id: A0A1D9FNB4
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1497:CLFO RS04830
gene id: 1497:CLFO_RS04830
uniprot id: A0A1D9FLG6
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

1497:CLFO RS18240
gene id: 1497:CLFO_RS18240
uniprot id: A0A1D9FHM6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1497:CLFO RS03565
gene id: 1497:CLFO_RS03565
uniprot id: A0A1D9FKX1
names: Similarity
messages: Belongs to the CinA family.

1497:CLFO RS20270
gene id: 1497:CLFO_RS20270
uniprot id: A0A1D9FIJ7
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

1497:CLFO RS11700
gene id: 1497:CLFO_RS11700
uniprot id: A0A1D9FQ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1497:CLFO RS11665
gene id: 1497:CLFO_RS11665
uniprot id: A0A1D9FQ03
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1497:CLFO RS16370
gene id: 1497:CLFO_RS16370
uniprot id: A0A1D9FSA4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1497:CLFO RS18645
gene id: 1497:CLFO_RS18645
uniprot id: A0A1D9FHX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS12070
gene id: 1497:CLFO_RS12070
uniprot id: A0A1D9FQ89
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1497:CLFO RS20405
gene id: 1497:CLFO_RS20405
uniprot id: A0A1D9FIW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1497:CLFO RS07550
gene id: 1497:CLFO_RS07550
uniprot id: A0A1D9FMT3
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1497:CLFO RS11735
gene id: 1497:CLFO_RS11735
uniprot id: A0A1D9FQF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1497:CLFO RS07020
gene id: 1497:CLFO_RS07020
uniprot id: A0A1D9FMI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1497:CLFO RS06605
gene id: 1497:CLFO_RS06605
uniprot id: A0A1D9FSJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS06975
gene id: 1497:CLFO_RS06975
uniprot id: A0A1D9FMR9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1497:CLFO RS06545
gene id: 1497:CLFO_RS06545
uniprot id: A0A1D9FMG3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1497:CLFO RS05505
gene id: 1497:CLFO_RS05505
uniprot id: A0A1D9FM89
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1497:CLFO RS10710
gene id: 1497:CLFO_RS10710
uniprot id: A0A1D9FPH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1497:CLFO RS20155
gene id: 1497:CLFO_RS20155
uniprot id: A0A1D9FIG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1497:CLFO RS06500
gene id: 1497:CLFO_RS06500
uniprot id: A0A1D9FMT5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1497:CLFO RS06820
gene id: 1497:CLFO_RS06820
uniprot id: A0A1D9FMN3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1497:CLFO RS20725
gene id: 1497:CLFO_RS20725
uniprot id: A0A1D9FJH4
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1497:CLFO RS17585
gene id: 1497:CLFO_RS17585
uniprot id: A0A1D9FHK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1497:CLFO RS11600
gene id: 1497:CLFO_RS11600
uniprot id: A0A1D9FPZ2
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

1497:CLFO RS11190
gene id: 1497:CLFO_RS11190
uniprot id: A0A1D9FPR8
names: Similarity
messages: Belongs to the UPF0102 family.

1497:CLFO RS15530
gene id: 1497:CLFO_RS15530
uniprot id: A0A1D9FRV7
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS08280
gene id: 1497:CLFO_RS08280
uniprot id: A0A1D9FND7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS20715
gene id: 1497:CLFO_RS20715
uniprot id: A0A1D9FIR9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1497:CLFO RS09265
gene id: 1497:CLFO_RS09265
uniprot id: A0A1D9FNP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1497:CLFO RS14220
gene id: 1497:CLFO_RS14220
uniprot id: A0A1D9FR84
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1497:CLFO RS09765
gene id: 1497:CLFO_RS09765
uniprot id: A0A1D9FNV2
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS03750
gene id: 1497:CLFO_RS03750
uniprot id: A0A1D9FL49
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS19840
gene id: 1497:CLFO_RS19840
uniprot id: A0A1D9FI85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS00115
gene id: 1497:CLFO_RS00115
uniprot id: A0A1D9FJ45
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS08420
gene id: 1497:CLFO_RS08420
uniprot id: A0A1D9FNR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1497:CLFO RS00805
gene id: 1497:CLFO_RS00805
uniprot id: A0A1D9FJF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1497:CLFO RS13095
gene id: 1497:CLFO_RS13095
uniprot id: A0A1D9FQW2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1497:CLFO RS18635
gene id: 1497:CLFO_RS18635
uniprot id: A0A1D9FIG5
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS19725
gene id: 1497:CLFO_RS19725
uniprot id: A0A1D9FI86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1497:CLFO RS11365
gene id: 1497:CLFO_RS11365
uniprot id: A0A1D9FQ01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1497:CLFO RS10110
gene id: 1497:CLFO_RS10110
uniprot id: A0A1D9FP30
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS14095
gene id: 1497:CLFO_RS14095
uniprot id: A0A1D9FRD3
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1497:CLFO RS03800
gene id: 1497:CLFO_RS03800
uniprot id: A0A1D9FL59
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1497:CLFO RS14355
gene id: 1497:CLFO_RS14355
uniprot id: A0A1D9FRI7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1497:CLFO RS09165
gene id: 1497:CLFO_RS09165
uniprot id: A0A1D9FNM7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1497:CLFO RS02175
gene id: 1497:CLFO_RS02175
uniprot id: A0A1D9FKF2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1497:CLFO RS12890
gene id: 1497:CLFO_RS12890
uniprot id: A0A1D9FQG7
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS06995
gene id: 1497:CLFO_RS06995
uniprot id: A0A1D9FMI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1497:CLFO RS15510
gene id: 1497:CLFO_RS15510
uniprot id: A0A1D9FS31
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS19980
gene id: 1497:CLFO_RS19980
uniprot id: A0A1D9FIZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS18285
gene id: 1497:CLFO_RS18285
uniprot id: A0A1D9FHN0
names: Similarity
messages: Belongs to the EamA transporter family.

1497:CLFO RS19785
gene id: 1497:CLFO_RS19785
uniprot id: A0A1D9FI95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1497:CLFO RS16860
gene id: 1497:CLFO_RS16860
uniprot id: A0A1D9FHI0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS06760
gene id: 1497:CLFO_RS06760
uniprot id: A0A1D9FMX5
names: Similarity
messages: Belongs to the peptidase M20A family.

1497:CLFO RS15120
gene id: 1497:CLFO_RS15120
uniprot id: A0A1D9FS89
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS13675
gene id: 1497:CLFO_RS13675
uniprot id: A0A1D9FQY2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1497:CLFO RS12380
gene id: 1497:CLFO_RS12380
uniprot id: A0A1D9FQ87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS17715
gene id: 1497:CLFO_RS17715
uniprot id: A0A1D9FHA9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS21395
gene id: 1497:CLFO_RS21395
uniprot id: A0A1D9FJ44
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1497:CLFO RS18290
gene id: 1497:CLFO_RS18290
uniprot id: A0A1D9FIE5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS02600
gene id: 1497:CLFO_RS02600
uniprot id: A0A1D9FKI5
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1497:CLFO RS14550
gene id: 1497:CLFO_RS14550
uniprot id: A0A1D9FRD4
names: Similarity
messages: Belongs to the UxaA family.

1497:CLFO RS03920
gene id: 1497:CLFO_RS03920
uniprot id: A0A1D9FL78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1497:CLFO RS07950
gene id: 1497:CLFO_RS07950
uniprot id: A0A1D9FN79
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1497:CLFO RS08635
gene id: 1497:CLFO_RS08635
uniprot id: A0A1D9FNW1
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1497:CLFO RS07195
gene id: 1497:CLFO_RS07195
uniprot id: A0A1D9FMS9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS19600
gene id: 1497:CLFO_RS19600
uniprot id: A0A1D9FIS0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1497:CLFO RS09715
gene id: 1497:CLFO_RS09715
uniprot id: A0A1D9FPF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1497:CLFO RS14300
gene id: 1497:CLFO_RS14300
uniprot id: A0A1D9FRA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1497:CLFO RS12190
gene id: 1497:CLFO_RS12190
uniprot id: A0A1D9FQF8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1497:CLFO RS11915
gene id: 1497:CLFO_RS11915
uniprot id: A0A1D9FQA7
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS20440
gene id: 1497:CLFO_RS20440
uniprot id: A0A1D9FIJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1497:CLFO RS12765
gene id: 1497:CLFO_RS12765
uniprot id: A0A1D9FQE7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1497:CLFO RS09045
gene id: 1497:CLFO_RS09045
uniprot id: A0A1D9FNK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS18070
gene id: 1497:CLFO_RS18070
uniprot id: A0A1D9FI93
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1497:CLFO RS02060
gene id: 1497:CLFO_RS02060
uniprot id: A0A1D9FK26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1497:CLFO RS08585
gene id: 1497:CLFO_RS08585
uniprot id: A0A1D9FNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1497:CLFO RS15160
gene id: 1497:CLFO_RS15160
uniprot id: A0A1D9FRN8
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

1497:CLFO RS15050
gene id: 1497:CLFO_RS15050
uniprot id: A0A1D9FRP0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS19875
gene id: 1497:CLFO_RS19875
uniprot id: A0A1D9FI96
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.

1497:CLFO RS20835
gene id: 1497:CLFO_RS20835
uniprot id: A0A1D9FIR6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1497:CLFO RS18380
gene id: 1497:CLFO_RS18380
uniprot id: A0A1D9FHQ7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1497:CLFO RS17960
gene id: 1497:CLFO_RS17960
uniprot id: A0A1D9FHH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS13945
gene id: 1497:CLFO_RS13945
uniprot id: A0A1D9FR21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS02620
gene id: 1497:CLFO_RS02620
uniprot id: A0A1D9FHT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1497:CLFO RS20515
gene id: 1497:CLFO_RS20515
uniprot id: A0A1D9FIT1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS12490
gene id: 1497:CLFO_RS12490
uniprot id: A0A1D9FQF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1497:CLFO RS13715
gene id: 1497:CLFO_RS13715
uniprot id: A0A1D9FR59
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS11850
gene id: 1497:CLFO_RS11850
uniprot id: A0A1D9FQ70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1497:CLFO RS09270
gene id: 1497:CLFO_RS09270
uniprot id: A0A1D9FNM8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1497:CLFO RS11685
gene id: 1497:CLFO_RS11685
uniprot id: A0A1D9FQE6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1497:CLFO RS01020
gene id: 1497:CLFO_RS01020
uniprot id: A0A1D9FJV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1497:CLFO RS14370
gene id: 1497:CLFO_RS14370
uniprot id: A0A1D9FRC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS03385
gene id: 1497:CLFO_RS03385
uniprot id: A0A1D9FL62
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1497:CLFO RS08490
gene id: 1497:CLFO_RS08490
uniprot id: A0A1D9FNK5
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1497:CLFO RS20645
gene id: 1497:CLFO_RS20645
uniprot id: A0A1D9FIN4
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS06740
gene id: 1497:CLFO_RS06740
uniprot id: A0A1D9FMD7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1497:CLFO RS15735
gene id: 1497:CLFO_RS15735
uniprot id: A0A1D9FS15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS05435
gene id: 1497:CLFO_RS05435
uniprot id: A0A1D9FLT1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1497:CLFO RS11920
gene id: 1497:CLFO_RS11920
uniprot id: A0A1D9FQ50
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS08475
gene id: 1497:CLFO_RS08475
uniprot id: A0A1D9FNF3
names: Similarity
messages: Belongs to the transpeptidase family.

1497:CLFO RS11680
gene id: 1497:CLFO_RS11680
uniprot id: A0A1D9FPW5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1497:CLFO RS17475
gene id: 1497:CLFO_RS17475
uniprot id: A0A1D9FH83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS05385
gene id: 1497:CLFO_RS05385
uniprot id: A0A1D9FM65
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1497:CLFO RS02315
gene id: 1497:CLFO_RS02315
uniprot id: A0A1D9FK87
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1497:CLFO RS11050
gene id: 1497:CLFO_RS11050
uniprot id: A0A1D9FPS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1497:CLFO RS12815
gene id: 1497:CLFO_RS12815
uniprot id: A0A1D9FQH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1497:CLFO RS19820
gene id: 1497:CLFO_RS19820
uniprot id: A0A1D9FI84
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1497:CLFO RS19745
gene id: 1497:CLFO_RS19745
uniprot id: A0A1D9FIJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1497:CLFO RS16330
gene id: 1497:CLFO_RS16330
uniprot id: A0A1D9FH94
names: Similarity
messages: Belongs to the UPF0251 family.

1497:CLFO RS10900
gene id: 1497:CLFO_RS10900
uniprot id: A0A1D9FPJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1497:CLFO RS19455
gene id: 1497:CLFO_RS19455
uniprot id: A0A1D9FI50
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS20760
gene id: 1497:CLFO_RS20760
uniprot id: A0A1D9FIT5
names: Similarity
messages: Belongs to the KdgT transporter family.

1497:CLFO RS13265
gene id: 1497:CLFO_RS13265
uniprot id: A0A1D9FL65
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1497:CLFO RS20810
gene id: 1497:CLFO_RS20810
uniprot id: A0A1D9FJD9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1497:CLFO RS19825
gene id: 1497:CLFO_RS19825
uniprot id: A0A1D9FIA8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1497:CLFO RS04860
gene id: 1497:CLFO_RS04860
uniprot id: A0A1D9FLJ1
names: Similarity
messages: Belongs to the UPF0145 family.

1497:CLFO RS19575
gene id: 1497:CLFO_RS19575
uniprot id: A0A1D9FI37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1497:CLFO RS00655
gene id: 1497:CLFO_RS00655
uniprot id: A0A1D9FJP6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS04695
gene id: 1497:CLFO_RS04695
uniprot id: A0A1D9FM33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1497:CLFO RS00845
gene id: 1497:CLFO_RS00845
uniprot id: A0A1D9FSJ1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1497:CLFO RS17120
gene id: 1497:CLFO_RS17120
uniprot id: A0A1D9FH28
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1497:CLFO RS02715
gene id: 1497:CLFO_RS02715
uniprot id: A0A1D9FL21
names: Similarity
messages: Belongs to the UPF0234 family.

1497:CLFO RS05745
gene id: 1497:CLFO_RS05745
uniprot id: A0A1D9FMK8
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1497:CLFO RS12575
gene id: 1497:CLFO_RS12575
uniprot id: A0A1D9FQL0
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS12920
gene id: 1497:CLFO_RS12920
uniprot id: A0A1D9FQS6
names: Similarity
messages: Belongs to the EamA transporter family.

1497:CLFO RS09890
gene id: 1497:CLFO_RS09890
uniprot id: A0A1D9FPH7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1497:CLFO RS11160
gene id: 1497:CLFO_RS11160
uniprot id: A0A1D9FPQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

1497:CLFO RS17650
gene id: 1497:CLFO_RS17650
uniprot id: A0A1D9FHE3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1497:CLFO RS14705
gene id: 1497:CLFO_RS14705
uniprot id: A0A1D9FRG0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1497:CLFO RS17950
gene id: 1497:CLFO_RS17950
uniprot id: A0A1D9FHG0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS14440
gene id: 1497:CLFO_RS14440
uniprot id: A0A1D9FRC9
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1497:CLFO RS02155
gene id: 1497:CLFO_RS02155
uniprot id: A0A1D9FK60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1497:CLFO RS16735
gene id: 1497:CLFO_RS16735
uniprot id: A0A1D9FGX8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1497:CLFO RS02080
gene id: 1497:CLFO_RS02080
uniprot id: A0A1D9FKG9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1497:CLFO RS04400
gene id: 1497:CLFO_RS04400
uniprot id: A0A1D9FSJ6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1497:CLFO RS21345
gene id: 1497:CLFO_RS21345
uniprot id: A0A1D9FJ07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1497:CLFO RS05455
gene id: 1497:CLFO_RS05455
uniprot id: A0A1D9FM76
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1497:CLFO RS00830
gene id: 1497:CLFO_RS00830
uniprot id: A0A1D9FJG1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1497:CLFO RS06965
gene id: 1497:CLFO_RS06965
uniprot id: A0A1D9FN09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1497:CLFO RS17140
gene id: 1497:CLFO_RS17140
uniprot id: A0A1D9FHD5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1497:CLFO RS05365
gene id: 1497:CLFO_RS05365
uniprot id: A0A1D9FLS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1497:CLFO RS07620
gene id: 1497:CLFO_RS07620
uniprot id: A0A1D9FMW0
names: Similarity
messages: Belongs to the UPF0047 family.

1497:CLFO RS01615
gene id: 1497:CLFO_RS01615
uniprot id: A0A1D9FSC6
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS01850
gene id: 1497:CLFO_RS01850
uniprot id: A0A1D9FKK1
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS18465
gene id: 1497:CLFO_RS18465
uniprot id: A0A1D9FID7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

1497:CLFO RS02800
gene id: 1497:CLFO_RS02800
uniprot id: A0A1D9FKI4
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS12560
gene id: 1497:CLFO_RS12560
uniprot id: A0A1D9FQW1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS11830
gene id: 1497:CLFO_RS11830
uniprot id: A0A1D9FPY9
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS18625
gene id: 1497:CLFO_RS18625
uniprot id: A0A1D9FI52
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS04625
gene id: 1497:CLFO_RS04625
uniprot id: A0A1D9FLD6
names: Similarity
messages: Belongs to the hemerythrin family.

1497:CLFO RS18510
gene id: 1497:CLFO_RS18510
uniprot id: A0A1D9FHZ4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS19845
gene id: 1497:CLFO_RS19845
uniprot id: A0A1D9FIL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1497:CLFO RS01710
gene id: 1497:CLFO_RS01710
uniprot id: A0A1D9FK00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1497:CLFO RS02040
gene id: 1497:CLFO_RS02040
uniprot id: A0A1D9FK31
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1497:CLFO RS02365
gene id: 1497:CLFO_RS02365
uniprot id: A0A1D9FKA1
names: Similarity
messages: Belongs to the HypE family.

1497:CLFO RS15715
gene id: 1497:CLFO_RS15715
uniprot id: A0A1D9FS71
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1497:CLFO RS02540
gene id: 1497:CLFO_RS02540
uniprot id: A0A1D9FKH5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1497:CLFO RS14630
gene id: 1497:CLFO_RS14630
uniprot id: A0A1D9FRP7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1497:CLFO RS14310
gene id: 1497:CLFO_RS14310
uniprot id: A0A1D9FRH7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1497:CLFO RS04295
gene id: 1497:CLFO_RS04295
uniprot id: A0A1D9FT30
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS05310
gene id: 1497:CLFO_RS05310
uniprot id: A0A1D9FME7
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1497:CLFO RS17230
gene id: 1497:CLFO_RS17230
uniprot id: A0A1D9FH59
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1497:CLFO RS13200
gene id: 1497:CLFO_RS13200
uniprot id: A0A1D9FQY5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS03600
gene id: 1497:CLFO_RS03600
uniprot id: A0A1D9FKX3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1497:CLFO RS10850
gene id: 1497:CLFO_RS10850
uniprot id: A0A1D9FPG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1497:CLFO RS19540
gene id: 1497:CLFO_RS19540
uniprot id: A0A1D9FIF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1497:CLFO RS09960
gene id: 1497:CLFO_RS09960
uniprot id: A0A1D9FP61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

1497:CLFO RS02550
gene id: 1497:CLFO_RS02550
uniprot id: A0A1D9FSN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1497:CLFO RS00540
gene id: 1497:CLFO_RS00540
uniprot id: A0A1D9FSH7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS05040
gene id: 1497:CLFO_RS05040
uniprot id: A0A1D9FMB2
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1497:CLFO RS09560
gene id: 1497:CLFO_RS09560
uniprot id: A0A1D9FP85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS05695
gene id: 1497:CLFO_RS05695
uniprot id: A0A1D9FLY1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1497:CLFO RS05530
gene id: 1497:CLFO_RS05530
uniprot id: A0A1D9FLW0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1497:CLFO RS04150
gene id: 1497:CLFO_RS04150
uniprot id: A0A1D9FL76
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1497:CLFO RS08940
gene id: 1497:CLFO_RS08940
uniprot id: A0A1D9FNP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1497:CLFO RS12415
gene id: 1497:CLFO_RS12415
uniprot id: A0A1D9FQH6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1497:CLFO RS10960
gene id: 1497:CLFO_RS10960
uniprot id: A0A1D9FPI4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1497:CLFO RS03730
gene id: 1497:CLFO_RS03730
uniprot id: A0A1D9FL00
names: Similarity
messages: Belongs to the mannitol dehydrogenase family. UxaB subfamily.

1497:CLFO RS09780
gene id: 1497:CLFO_RS09780
uniprot id: A0A1D9FPF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1497:CLFO RS01680
gene id: 1497:CLFO_RS01680
uniprot id: A0A1D9FKL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1497:CLFO RS00110
gene id: 1497:CLFO_RS00110
uniprot id: A0A1D9FJW5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1497:CLFO RS11420
gene id: 1497:CLFO_RS11420
uniprot id: A0A1D9FPZ6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS20460
gene id: 1497:CLFO_RS20460
uniprot id: A0A1D9FIX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1497:CLFO RS14410
gene id: 1497:CLFO_RS14410
uniprot id: A0A1D9FRJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1497:CLFO RS12520
gene id: 1497:CLFO_RS12520
uniprot id: A0A1D9FQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1497:CLFO RS13090
gene id: 1497:CLFO_RS13090
uniprot id: A0A1D9FQV4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1497:CLFO RS13050
gene id: 1497:CLFO_RS13050
uniprot id: A0A1D9FT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS04995
gene id: 1497:CLFO_RS04995
uniprot id: A0A1D9FLJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1497:CLFO RS18905
gene id: 1497:CLFO_RS18905
uniprot id: A0A1D9FHY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Probably a homodimer.

1497:CLFO RS12540
gene id: 1497:CLFO_RS12540
uniprot id: A0A1D9FQG3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1497:CLFO RS19780
gene id: 1497:CLFO_RS19780
uniprot id: A0A1D9FI77
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1497:CLFO RS00290
gene id: 1497:CLFO_RS00290
uniprot id: A0A1D9FJ93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS02325
gene id: 1497:CLFO_RS02325
uniprot id: A0A1D9FK74
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1497:CLFO RS05035
gene id: 1497:CLFO_RS05035
uniprot id: A0A1D9FLL6
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1497:CLFO RS21385
gene id: 1497:CLFO_RS21385
uniprot id: A0A1D9FJN7
names: Similarity
messages: Belongs to the ParB family.

1497:CLFO RS20470
gene id: 1497:CLFO_RS20470
uniprot id: A0A1D9FJ80
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS20015
gene id: 1497:CLFO_RS20015
uniprot id: A0A1D9FJ48
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS09360
gene id: 1497:CLFO_RS09360
uniprot id: A0A1D9FP65
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1497:CLFO RS04050
gene id: 1497:CLFO_RS04050
uniprot id: A0A1D9FL40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS17860
gene id: 1497:CLFO_RS17860
uniprot id: A0A1D9FHE8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1497:CLFO RS07985
gene id: 1497:CLFO_RS07985
uniprot id: A0A1D9FMZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1497:CLFO RS16555
gene id: 1497:CLFO_RS16555
uniprot id: A0A1D9FH00
names: Function
names: PTM
names: Similarity
messages: Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
messages: Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.
messages: Requires the activating protein CutD to generate the key active site glycyl radical on Gly-821 that is involved in catalysis.

1497:CLFO RS01645
gene id: 1497:CLFO_RS01645
uniprot id: A0A1D9FKF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS15705
gene id: 1497:CLFO_RS15705
uniprot id: A0A1D9FS16
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1497:CLFO RS03405
gene id: 1497:CLFO_RS03405
uniprot id: A0A1D9FLH9
names: Similarity
messages: Belongs to the peptidase S8 family.

1497:CLFO RS02160
gene id: 1497:CLFO_RS02160
uniprot id: A0A1D9FKU8
names: Subcellular Location Annotation
messages: Bacterial microcompartment

1497:CLFO RS00280
gene id: 1497:CLFO_RS00280
uniprot id: A0A1D9FJT4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1497:CLFO RS14585
gene id: 1497:CLFO_RS14585
uniprot id: A0A1D9FRM3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS00560
gene id: 1497:CLFO_RS00560
uniprot id: A0A1D9FJF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1497:CLFO RS03670
gene id: 1497:CLFO_RS03670
uniprot id: A0A1D9FKX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS01745
gene id: 1497:CLFO_RS01745
uniprot id: A0A1D9FK48
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS14915
gene id: 1497:CLFO_RS14915
uniprot id: A0A1D9FRU2
names: Similarity
messages: Belongs to the pirin family.

1497:CLFO RS15550
gene id: 1497:CLFO_RS15550
uniprot id: A0A1D9FS38
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1497:CLFO RS04425
gene id: 1497:CLFO_RS04425
uniprot id: A0A1D9FLC5
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS18690
gene id: 1497:CLFO_RS18690
uniprot id: A0A1D9FIH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1497:CLFO RS01165
gene id: 1497:CLFO_RS01165
uniprot id: A0A1D9FJM3
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS02135
gene id: 1497:CLFO_RS02135
uniprot id: A0A1D9FKI1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS13870
gene id: 1497:CLFO_RS13870
uniprot id: A0A1D9FR87
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1497:CLFO RS00705
gene id: 1497:CLFO_RS00705
uniprot id: A0A1D9FJQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS18455
gene id: 1497:CLFO_RS18455
uniprot id: A0A1D9FI25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

1497:CLFO RS01080
gene id: 1497:CLFO_RS01080
uniprot id: A0A1D9FK81
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1497:CLFO RS12700
gene id: 1497:CLFO_RS12700
uniprot id: A0A1D9FQF1
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS14045
gene id: 1497:CLFO_RS14045
uniprot id: A0A1D9FR43
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1497:CLFO RS08425
gene id: 1497:CLFO_RS08425
uniprot id: A0A1D9FNJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1497:CLFO RS12775
gene id: 1497:CLFO_RS12775
uniprot id: A0A1D9FQE9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1497:CLFO RS02470
gene id: 1497:CLFO_RS02470
uniprot id: A0A1D9FK94
names: Similarity
messages: Belongs to the HupF/HypC family.

1497:CLFO RS09865
gene id: 1497:CLFO_RS09865
uniprot id: A0A1D9FSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1497:CLFO RS15385
gene id: 1497:CLFO_RS15385
uniprot id: A0A1D9FT14
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS05005
gene id: 1497:CLFO_RS05005
uniprot id: A0A1D9FLS5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1497:CLFO RS13960
gene id: 1497:CLFO_RS13960
uniprot id: A0A1D9FSV1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1497:CLFO RS20900
gene id: 1497:CLFO_RS20900
uniprot id: A0A1D9FNE3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1497:CLFO RS14285
gene id: 1497:CLFO_RS14285
uniprot id: A0A1D9FR93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1497:CLFO RS05420
gene id: 1497:CLFO_RS05420
uniprot id: A0A1D9FLW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1497:CLFO RS03305
gene id: 1497:CLFO_RS03305
uniprot id: A0A1D9FSN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS00245
gene id: 1497:CLFO_RS00245
uniprot id: A0A1D9FJ58
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1497:CLFO RS16225
gene id: 1497:CLFO_RS16225
uniprot id: A0A1D9FH75
names: Similarity
messages: Belongs to the peptidase S8 family.

1497:CLFO RS11695
gene id: 1497:CLFO_RS11695
uniprot id: A0A1D9FQ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1497:CLFO RS15040
gene id: 1497:CLFO_RS15040
uniprot id: A0A1D9FRV1
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS18385
gene id: 1497:CLFO_RS18385
uniprot id: A0A1D9FHP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1497:CLFO RS14000
gene id: 1497:CLFO_RS14000
uniprot id: A0A1D9FR28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS11530
gene id: 1497:CLFO_RS11530
uniprot id: A0A1D9FQ38
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1497:CLFO RS03820
gene id: 1497:CLFO_RS03820
uniprot id: A0A1D9FL01
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1497:CLFO RS11370
gene id: 1497:CLFO_RS11370
uniprot id: A0A1D9FPU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1497:CLFO RS13215
gene id: 1497:CLFO_RS13215
uniprot id: A0A1D9FQR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1497:CLFO RS19615
gene id: 1497:CLFO_RS19615
uniprot id: A0A1D9FI49
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1497:CLFO RS09800
gene id: 1497:CLFO_RS09800
uniprot id: A0A1D9FP49
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS12030
gene id: 1497:CLFO_RS12030
uniprot id: A0A1D9FQ32
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS11740
gene id: 1497:CLFO_RS11740
uniprot id: A0A1D9FPX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1497:CLFO RS19920
gene id: 1497:CLFO_RS19920
uniprot id: A0A1D9FIP9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS04365
gene id: 1497:CLFO_RS04365
uniprot id: A0A1D9FLB5
names: Similarity
messages: Belongs to the SleB family.

1497:CLFO RS06935
gene id: 1497:CLFO_RS06935
uniprot id: A0A1D9FMW7
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS19935
gene id: 1497:CLFO_RS19935
uniprot id: A0A1D9FIC7
names: Similarity
messages: Belongs to the class II ribonucleoside-triphosphate reductase family.

1497:CLFO RS18570
gene id: 1497:CLFO_RS18570
uniprot id: A0A1D9FHT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1497:CLFO RS10840
gene id: 1497:CLFO_RS10840
uniprot id: A0A1D9FPG1
names: Similarity
messages: Belongs to the peptidase M16 family.

1497:CLFO RS19905
gene id: 1497:CLFO_RS19905
uniprot id: A0A1D9FIH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1497:CLFO RS20535
gene id: 1497:CLFO_RS20535
uniprot id: A0A1D9FIP7
names: Similarity
messages: Belongs to the UxaA family.

1497:CLFO RS09930
gene id: 1497:CLFO_RS09930
uniprot id: A0A1D9FNY5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS18915
gene id: 1497:CLFO_RS18915
uniprot id: A0A1D9FI63
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS20310
gene id: 1497:CLFO_RS20310
uniprot id: A0A1D9FIP8
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS09490
gene id: 1497:CLFO_RS09490
uniprot id: A0A1D9FPA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS18550
gene id: 1497:CLFO_RS18550
uniprot id: A0A1D9FS57
names: Similarity
messages: Belongs to the thioredoxin family.

1497:CLFO RS15745
gene id: 1497:CLFO_RS15745
uniprot id: A0A1D9FRY6
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1497:CLFO RS18440
gene id: 1497:CLFO_RS18440
uniprot id: A0A1D9FHQ8
names: Similarity
messages: Belongs to the class-I fumarase family.

1497:CLFO RS03615
gene id: 1497:CLFO_RS03615
uniprot id: A0A1D9FKY8
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1497:CLFO RS15075
gene id: 1497:CLFO_RS15075
uniprot id: A0A1D9FRN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS19390
gene id: 1497:CLFO_RS19390
uniprot id: A0A1D9FIE9
names: Similarity
messages: Belongs to the peptidase S66 family.

1497:CLFO RS11230
gene id: 1497:CLFO_RS11230
uniprot id: A0A1D9FQ64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1497:CLFO RS05380
gene id: 1497:CLFO_RS05380
uniprot id: A0A1D9FME2
names: Subcellular Location Annotation
messages: Cell membrane

1497:CLFO RS06905
gene id: 1497:CLFO_RS06905
uniprot id: A0A1D9FMG4
names: Similarity
messages: Belongs to the hemerythrin family.

1497:CLFO RS01375
gene id: 1497:CLFO_RS01375
uniprot id: A0A1D9FK32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1497:CLFO RS01550
gene id: 1497:CLFO_RS01550
uniprot id: A0A1D9FJW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1497:CLFO RS00455
gene id: 1497:CLFO_RS00455
uniprot id: A0A1D9FJ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1497:CLFO RS00690
gene id: 1497:CLFO_RS00690
uniprot id: A0A1D9FJE1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1497:CLFO RS08570
gene id: 1497:CLFO_RS08570
uniprot id: A0A1D9FN97
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1497:CLFO RS03045
gene id: 1497:CLFO_RS03045
uniprot id: A0A1D9FKS1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1497:CLFO RS12785
gene id: 1497:CLFO_RS12785
uniprot id: A0A1D9FQP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS06950
gene id: 1497:CLFO_RS06950
uniprot id: A0A1D9FMI4
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS20500
gene id: 1497:CLFO_RS20500
uniprot id: A0A1D9FJD6
names: Similarity
messages: Belongs to the UPF0237 family.

1497:CLFO RS14490
gene id: 1497:CLFO_RS14490
uniprot id: A0A1D9FRE4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1497:CLFO RS18605
gene id: 1497:CLFO_RS18605
uniprot id: A0A1D9FHV0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS13100
gene id: 1497:CLFO_RS13100
uniprot id: A0A1D9FQX5
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1497:CLFO RS02790
gene id: 1497:CLFO_RS02790
uniprot id: A0A1D9FKH8
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1497:CLFO RS04680
gene id: 1497:CLFO_RS04680
uniprot id: A0A1D9FLE6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1497:CLFO RS08995
gene id: 1497:CLFO_RS08995
uniprot id: A0A1D9FNJ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS19855
gene id: 1497:CLFO_RS19855
uniprot id: A0A1D9FIH0
names: Similarity
messages: Belongs to the ycf81 family.

1497:CLFO RS00685
gene id: 1497:CLFO_RS00685
uniprot id: A0A1D9FJG7
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS00895
gene id: 1497:CLFO_RS00895
uniprot id: A0A1D9FJT2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS02520
gene id: 1497:CLFO_RS02520
uniprot id: A0A1D9FL12
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1497:CLFO RS02015
gene id: 1497:CLFO_RS02015
uniprot id: A0A1D9FKN0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1497:CLFO RS12795
gene id: 1497:CLFO_RS12795
uniprot id: A0A1D9FQS1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1497:CLFO RS17885
gene id: 1497:CLFO_RS17885
uniprot id: A0A1D9FHI3
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1497:CLFO RS06705
gene id: 1497:CLFO_RS06705
uniprot id: A0A1D9FMW8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1497:CLFO RS12935
gene id: 1497:CLFO_RS12935
uniprot id: A0A1D9FQN6
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS00960
gene id: 1497:CLFO_RS00960
uniprot id: A0A1D9FJI0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1497:CLFO RS03805
gene id: 1497:CLFO_RS03805
uniprot id: A0A1D9FLL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1497:CLFO RS13140
gene id: 1497:CLFO_RS13140
uniprot id: A0A1D9FQW5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1497:CLFO RS09550
gene id: 1497:CLFO_RS09550
uniprot id: A0A1D9FNZ7
names: Similarity
messages: Belongs to the GSP E family.

1497:CLFO RS08265
gene id: 1497:CLFO_RS08265
uniprot id: A0A1D9FN47
names: Similarity
messages: Belongs to the IMPACT family.

1497:CLFO RS11270
gene id: 1497:CLFO_RS11270
uniprot id: A0A1D9FPQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1497:CLFO RS19610
gene id: 1497:CLFO_RS19610
uniprot id: A0A1D9FI78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1497:CLFO RS09245
gene id: 1497:CLFO_RS09245
uniprot id: A0A1D9FNZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1497:CLFO RS11040
gene id: 1497:CLFO_RS11040
uniprot id: A0A1D9FPQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1497:CLFO RS04970
gene id: 1497:CLFO_RS04970
uniprot id: A0A1D9FLL3
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1497:CLFO RS13645
gene id: 1497:CLFO_RS13645
uniprot id: A0A1D9FR13
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS08495
gene id: 1497:CLFO_RS08495
uniprot id: A0A1D9FNE2
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1497:CLFO RS10855
gene id: 1497:CLFO_RS10855
uniprot id: A0A1D9FPY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1497:CLFO RS16170
gene id: 1497:CLFO_RS16170
uniprot id: A0A1D9FGT8
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS05165
gene id: 1497:CLFO_RS05165
uniprot id: A0A1D9FLZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS12485
gene id: 1497:CLFO_RS12485
uniprot id: A0A1D9FQK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1497:CLFO RS11145
gene id: 1497:CLFO_RS11145
uniprot id: A0A1D9FPS9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1497:CLFO RS05825
gene id: 1497:CLFO_RS05825
uniprot id: A0A1D9FMG7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1497:CLFO RS21400
gene id: 1497:CLFO_RS21400
uniprot id: A0A1D9FJ19
names: Similarity
messages: Belongs to the ParB family.

1497:CLFO RS03710
gene id: 1497:CLFO_RS03710
uniprot id: A0A1D9FLC4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1497:CLFO RS15425
gene id: 1497:CLFO_RS15425
uniprot id: A0A1D9FL65
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1497:CLFO RS00820
gene id: 1497:CLFO_RS00820
uniprot id: A0A1D9FK86
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS11245
gene id: 1497:CLFO_RS11245
uniprot id: A0A1D9FPW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1497:CLFO RS12510
gene id: 1497:CLFO_RS12510
uniprot id: A0A1D9FQV1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1497:CLFO RS06410
gene id: 1497:CLFO_RS06410
uniprot id: A0A1D9FM93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1497:CLFO RS18230
gene id: 1497:CLFO_RS18230
uniprot id: A0A1D9FHM1
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1497:CLFO RS19715
gene id: 1497:CLFO_RS19715
uniprot id: A0A1D9FI95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1497:CLFO RS12695
gene id: 1497:CLFO_RS12695
uniprot id: A0A1D9FQJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1497:CLFO RS10930
gene id: 1497:CLFO_RS10930
uniprot id: A0A1D9FPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1497:CLFO RS13105
gene id: 1497:CLFO_RS13105
uniprot id: A0A1D9FQR6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1497:CLFO RS02820
gene id: 1497:CLFO_RS02820
uniprot id: A0A1D9FKS6
names: Similarity
messages: Belongs to the UPF0751 family.

1497:CLFO RS02045
gene id: 1497:CLFO_RS02045
uniprot id: A0A1D9FK55
names: Similarity
messages: Belongs to the GARS family.

1497:CLFO RS05765
gene id: 1497:CLFO_RS05765
uniprot id: A0A1D9FMK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1497:CLFO RS17700
gene id: 1497:CLFO_RS17700
uniprot id: A0A1D9FHQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1497:CLFO RS01880
gene id: 1497:CLFO_RS01880
uniprot id: A0A1D9FKP9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1497:CLFO RS02385
gene id: 1497:CLFO_RS02385
uniprot id: A0A1D9FKF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1497:CLFO RS05245
gene id: 1497:CLFO_RS05245
uniprot id: A0A1D9FLQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS01515
gene id: 1497:CLFO_RS01515
uniprot id: A0A1D9FJT0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1497:CLFO RS18095
gene id: 1497:CLFO_RS18095
uniprot id: A0A1D9FHY3
names: Similarity
messages: Belongs to the Ahb/Nir family.

1497:CLFO RS19345
gene id: 1497:CLFO_RS19345
uniprot id: A0A1D9FHZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1497:CLFO RS10125
gene id: 1497:CLFO_RS10125
uniprot id: A0A1D9FP31
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS08595
gene id: 1497:CLFO_RS08595
uniprot id: A0A1D9FNF9
names: Similarity
messages: Belongs to the RutC family.

1497:CLFO RS12470
gene id: 1497:CLFO_RS12470
uniprot id: A0A1D9FQF7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1497:CLFO RS14620
gene id: 1497:CLFO_RS14620
uniprot id: A0A1D9FRH4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS10690
gene id: 1497:CLFO_RS10690
uniprot id: A0A1D9FPJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1497:CLFO RS14765
gene id: 1497:CLFO_RS14765
uniprot id: A0A1D9FS29
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1497:CLFO RS05605
gene id: 1497:CLFO_RS05605
uniprot id: A0A1D9FMI2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS10660
gene id: 1497:CLFO_RS10660
uniprot id: A0A1D9FSS9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1497:CLFO RS00730
gene id: 1497:CLFO_RS00730
uniprot id: A0A1D9FJE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS15605
gene id: 1497:CLFO_RS15605
uniprot id: A0A1D9FS50
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1497:CLFO RS10825
gene id: 1497:CLFO_RS10825
uniprot id: A0A1D9FTD2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1497:CLFO RS04690
gene id: 1497:CLFO_RS04690
uniprot id: A0A1D9FLM2
names: Similarity
messages: Belongs to the YciI family.

1497:CLFO RS02900
gene id: 1497:CLFO_RS02900
uniprot id: A0A1D9FKL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1497:CLFO RS11265
gene id: 1497:CLFO_RS11265
uniprot id: A0A1D9FPP1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1497:CLFO RS15980
gene id: 1497:CLFO_RS15980
uniprot id: A0A1D9FGH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

1497:CLFO RS01640
gene id: 1497:CLFO_RS01640
uniprot id: A0A1D9FK25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS03620
gene id: 1497:CLFO_RS03620
uniprot id: A0A1D9FKX8
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1497:CLFO RS03255
gene id: 1497:CLFO_RS03255
uniprot id: A0A1D9FL45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1497:CLFO RS14545
gene id: 1497:CLFO_RS14545
uniprot id: A0A1D9FRF0
names: Similarity
messages: Belongs to the DapA family.

1497:CLFO RS06300
gene id: 1497:CLFO_RS06300
uniprot id: A0A1D9FST8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1497:CLFO RS05440
gene id: 1497:CLFO_RS05440
uniprot id: A0A1D9FM41
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1497:CLFO RS04485
gene id: 1497:CLFO_RS04485
uniprot id: A0A1D9FLQ6
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1497:CLFO RS14845
gene id: 1497:CLFO_RS14845
uniprot id: A0A1D9FRS3
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS20140
gene id: 1497:CLFO_RS20140
uniprot id: A0A1D9FIT6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1497:CLFO RS01975
gene id: 1497:CLFO_RS01975
uniprot id: A0A1D9FK47
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1497:CLFO RS05025
gene id: 1497:CLFO_RS05025
uniprot id: A0A1D9FLL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1497:CLFO RS15495
gene id: 1497:CLFO_RS15495
uniprot id: A0A1D9FRX6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1497:CLFO RS13290
gene id: 1497:CLFO_RS13290
uniprot id: A0A1D9FRA1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1497:CLFO RS11300
gene id: 1497:CLFO_RS11300
uniprot id: A0A1D9FPZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1497:CLFO RS09555
gene id: 1497:CLFO_RS09555
uniprot id: A0A1D9FP14
names: Similarity
messages: Belongs to the GSP E family.

1497:CLFO RS05925
gene id: 1497:CLFO_RS05925
uniprot id: A0A1D9FMC9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1497:CLFO RS11705
gene id: 1497:CLFO_RS11705
uniprot id: A0A1D9FQ76
names: Similarity
messages: Belongs to the UPF0749 family.

1497:CLFO RS21350
gene id: 1497:CLFO_RS21350
uniprot id: A0A1D9FJ31
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS03720
gene id: 1497:CLFO_RS03720
uniprot id: A0A1D9FKY3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1497:CLFO RS18160
gene id: 1497:CLFO_RS18160
uniprot id: A0A1D9FHP2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1497:CLFO RS16595
gene id: 1497:CLFO_RS16595
uniprot id: A0A1D9FGU3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS16165
gene id: 1497:CLFO_RS16165
uniprot id: A0A1D9FGW6
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS01620
gene id: 1497:CLFO_RS01620
uniprot id: A0A1D9FKK5
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS01435
gene id: 1497:CLFO_RS01435
uniprot id: A0A1D9FJU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1497:CLFO RS19870
gene id: 1497:CLFO_RS19870
uniprot id: A0A1D9FIC4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

1497:CLFO RS14890
gene id: 1497:CLFO_RS14890
uniprot id: A0A1D9FS48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1497:CLFO RS10080
gene id: 1497:CLFO_RS10080
uniprot id: A0A1D9FP93
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS01465
gene id: 1497:CLFO_RS01465
uniprot id: A0A1D9FK33
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1497:CLFO RS00860
gene id: 1497:CLFO_RS00860
uniprot id: A0A1D9FJU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1497:CLFO RS16875
gene id: 1497:CLFO_RS16875
uniprot id: A0A1D9FGV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1497:CLFO RS03985
gene id: 1497:CLFO_RS03985
uniprot id: A0A1D9FLQ0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1497:CLFO RS01835
gene id: 1497:CLFO_RS01835
uniprot id: A0A1D9FJZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1497:CLFO RS15175
gene id: 1497:CLFO_RS15175
uniprot id: A0A1D9FRQ1
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1497:CLFO RS16675
gene id: 1497:CLFO_RS16675
uniprot id: A0A1D9FGW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1497:CLFO RS20890
gene id: 1497:CLFO_RS20890
uniprot id: A0A1D9FIS9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS14570
gene id: 1497:CLFO_RS14570
uniprot id: A0A1D9FRG2
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS19420
gene id: 1497:CLFO_RS19420
uniprot id: A0A1D9FI11
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1497:CLFO RS05865
gene id: 1497:CLFO_RS05865
uniprot id: A0A1D9FM95
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1497:CLFO RS18580
gene id: 1497:CLFO_RS18580
uniprot id: A0A1D9FI04
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS13115
gene id: 1497:CLFO_RS13115
uniprot id: A0A1D9FQP4
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS06570
gene id: 1497:CLFO_RS06570
uniprot id: A0A1D9FMC1
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

1497:CLFO RS14995
gene id: 1497:CLFO_RS14995
uniprot id: A0A1D9FRM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1497:CLFO RS07060
gene id: 1497:CLFO_RS07060
uniprot id: A0A1D9FMM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1497:CLFO RS15080
gene id: 1497:CLFO_RS15080
uniprot id: A0A1D9FRQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS04415
gene id: 1497:CLFO_RS04415
uniprot id: A0A1D9FLY0
names: Similarity
messages: Belongs to the UPF0045 family.

1497:CLFO RS09965
gene id: 1497:CLFO_RS09965
uniprot id: A0A1D9FP81
names: Similarity
messages: Belongs to the UxaA family.

1497:CLFO RS11205
gene id: 1497:CLFO_RS11205
uniprot id: A0A1D9FPX1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1497:CLFO RS20710
gene id: 1497:CLFO_RS20710
uniprot id: A0A1D9FIP6
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1497:CLFO RS17965
gene id: 1497:CLFO_RS17965
uniprot id: A0A1D9FHS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS15145
gene id: 1497:CLFO_RS15145
uniprot id: A0A1D9FRX2
names: Subcellular Location Annotation
messages: Cytoplasm

1497:CLFO RS01125
gene id: 1497:CLFO_RS01125
uniprot id: A0A1D9FKC3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1497:CLFO RS12255
gene id: 1497:CLFO_RS12255
uniprot id: A0A1D9FQG8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1497:CLFO RS19655
gene id: 1497:CLFO_RS19655
uniprot id: A0A1D9FIJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1497:CLFO RS04065
gene id: 1497:CLFO_RS04065
uniprot id: A0A1D9FLU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1497:CLFO RS10935
gene id: 1497:CLFO_RS10935
uniprot id: A0A1D9FPU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1497:CLFO RS12185
gene id: 1497:CLFO_RS12185
uniprot id: A0A1D9FTE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS15165
gene id: 1497:CLFO_RS15165
uniprot id: A0A1D9FRP1
names: Similarity
messages: Belongs to the GerABKA family.

1497:CLFO RS02880
gene id: 1497:CLFO_RS02880
uniprot id: A0A1D9FL50
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1497:CLFO RS16685
gene id: 1497:CLFO_RS16685
uniprot id: A0A1D9FGT1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1497:CLFO RS07115
gene id: 1497:CLFO_RS07115
uniprot id: A0A1D9FMJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1497:CLFO RS10750
gene id: 1497:CLFO_RS10750
uniprot id: A0A1D9FSR7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS17665
gene id: 1497:CLFO_RS17665
uniprot id: A0A1D9FHA6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1497:CLFO RS19895
gene id: 1497:CLFO_RS19895
uniprot id: A0A1D9FI97
names: Similarity
messages: Belongs to the CtsR family.

1497:CLFO RS20290
gene id: 1497:CLFO_RS20290
uniprot id: A0A1D9FJ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1497:CLFO RS12500
gene id: 1497:CLFO_RS12500
uniprot id: A0A1D9FQC2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1497:CLFO RS21430
gene id: 1497:CLFO_RS21430
uniprot id: A0A1D9FJ92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1497:CLFO RS12290
gene id: 1497:CLFO_RS12290
uniprot id: A0A1D9FQC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1497:CLFO RS10770
gene id: 1497:CLFO_RS10770
uniprot id: A0A1D9FPI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1497:CLFO RS15005
gene id: 1497:CLFO_RS15005
uniprot id: A0A1D9FT57
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS03590
gene id: 1497:CLFO_RS03590
uniprot id: A0A1D9FLI0
names: Similarity
messages: Belongs to the asp23 family.

1497:CLFO RS11350
gene id: 1497:CLFO_RS11350
uniprot id: A0A1D9FPU8
names: Similarity
messages: Belongs to the asp23 family.

1497:CLFO RS06835
gene id: 1497:CLFO_RS06835
uniprot id: A0A1D9FMU8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS11990
gene id: 1497:CLFO_RS11990
uniprot id: A0A1D9FQ23
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1497:CLFO RS02765
gene id: 1497:CLFO_RS02765
uniprot id: A0A1D9FKR7
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1497:CLFO RS19620
gene id: 1497:CLFO_RS19620
uniprot id: A0A1D9FI64
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1497:CLFO RS00415
gene id: 1497:CLFO_RS00415
uniprot id: A0A1D9FJ95
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1497:CLFO RS05370
gene id: 1497:CLFO_RS05370
uniprot id: A0A1D9FM28
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1497:CLFO RS03685
gene id: 1497:CLFO_RS03685
uniprot id: A0A1D9FLN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1497:CLFO RS12075
gene id: 1497:CLFO_RS12075
uniprot id: A0A1D9FQB6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1497:CLFO RS20415
gene id: 1497:CLFO_RS20415
uniprot id: A0A1D9FJ70
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1497:CLFO RS05000
gene id: 1497:CLFO_RS05000
uniprot id: A0A1D9FLW7
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1497:CLFO RS18560
gene id: 1497:CLFO_RS18560
uniprot id: A0A1D9FHS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1497:CLFO RS04235
gene id: 1497:CLFO_RS04235
uniprot id: A0A1D9FLX8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1497:CLFO RS18200
gene id: 1497:CLFO_RS18200
uniprot id: A0A1D9FI89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1497:CLFO RS03030
gene id: 1497:CLFO_RS03030
uniprot id: A0A1D9FLB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1497:CLFO RS01580
gene id: 1497:CLFO_RS01580
uniprot id: A0A1D9FK15
names: Similarity
messages: Belongs to the GppA/Ppx family.

1497:CLFO RS03025
gene id: 1497:CLFO_RS03025
uniprot id: A0A1D9FKM1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1497:CLFO RS00340
gene id: 1497:CLFO_RS00340
uniprot id: A0A1D9FJA3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1497:CLFO RS09545
gene id: 1497:CLFO_RS09545
uniprot id: A0A1D9FNT6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS07825
gene id: 1497:CLFO_RS07825
uniprot id: A0A1D9FMW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1497:CLFO RS00320
gene id: 1497:CLFO_RS00320
uniprot id: A0A1D9FJI6
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1497:CLFO RS06320
gene id: 1497:CLFO_RS06320
uniprot id: A0A1D9FMQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1497:CLFO RS13125
gene id: 1497:CLFO_RS13125
uniprot id: A0A1D9FR76
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS02445
gene id: 1497:CLFO_RS02445
uniprot id: A0A1D9FSD1
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1497:CLFO RS03020
gene id: 1497:CLFO_RS03020
uniprot id: A0A1D9FKN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1497:CLFO RS12405
gene id: 1497:CLFO_RS12405
uniprot id: A0A1D9FQ82
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1497:CLFO RS12495
gene id: 1497:CLFO_RS12495
uniprot id: A0A1D9FQA8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1497:CLFO RS11995
gene id: 1497:CLFO_RS11995
uniprot id: A0A1D9FQK1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1497:CLFO RS05055
gene id: 1497:CLFO_RS05055
uniprot id: A0A1D9FLX4
names: Similarity
messages: Belongs to the UPF0251 family.

1497:CLFO RS05445
gene id: 1497:CLFO_RS05445
uniprot id: A0A1D9FM07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1497:CLFO RS16780
gene id: 1497:CLFO_RS16780
uniprot id: A0A1D9FH72
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS10650
gene id: 1497:CLFO_RS10650
uniprot id: A0A1D9FPH0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS15640
gene id: 1497:CLFO_RS15640
uniprot id: A0A1D9FSH9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS06675
gene id: 1497:CLFO_RS06675
uniprot id: A0A1D9FMC0
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

1497:CLFO RS01970
gene id: 1497:CLFO_RS01970
uniprot id: A0A1D9FKF3
names: Similarity
messages: Belongs to the YoeB family.

1497:CLFO RS04890
gene id: 1497:CLFO_RS04890
uniprot id: A0A1D9FLU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1497:CLFO RS03050
gene id: 1497:CLFO_RS03050
uniprot id: A0A1D9FL84
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1497:CLFO RS15970
gene id: 1497:CLFO_RS15970
uniprot id: A0A1D9FGG1
names: Similarity
messages: Belongs to the UPF0749 family.

1497:CLFO RS11775
gene id: 1497:CLFO_RS11775
uniprot id: A0A1D9FPY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1497:CLFO RS00030
gene id: 1497:CLFO_RS00030
uniprot id: A0A1D9FJ34
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1497:CLFO RS17410
gene id: 1497:CLFO_RS17410
uniprot id: A0A1D9FHW6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1497:CLFO RS05545
gene id: 1497:CLFO_RS05545
uniprot id: A0A1D9FM60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS19995
gene id: 1497:CLFO_RS19995
uniprot id: A0A1D9FIB4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS15615
gene id: 1497:CLFO_RS15615
uniprot id: A0A1D9FS52
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS18025
gene id: 1497:CLFO_RS18025
uniprot id: A0A1D9FHT3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS19690
gene id: 1497:CLFO_RS19690
uniprot id: A0A1D9FI55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1497:CLFO RS00975
gene id: 1497:CLFO_RS00975
uniprot id: A0A1D9FK59
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS04075
gene id: 1497:CLFO_RS04075
uniprot id: A0A1D9FLG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1497:CLFO RS01520
gene id: 1497:CLFO_RS01520
uniprot id: A0A1D9FK43
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1497:CLFO RS21440
gene id: 1497:CLFO_RS21440
uniprot id: A0A1D9FJF3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1497:CLFO RS21420
gene id: 1497:CLFO_RS21420
uniprot id: A0A1D9FJ25
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

1497:CLFO RS19585
gene id: 1497:CLFO_RS19585
uniprot id: A0A1D9FI35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1497:CLFO RS07685
gene id: 1497:CLFO_RS07685
uniprot id: A0A1D9FN52
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1497:CLFO RS01730
gene id: 1497:CLFO_RS01730
uniprot id: A0A1D9FKM4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS10525
gene id: 1497:CLFO_RS10525
uniprot id: A0A1D9FPG7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1497:CLFO RS13680
gene id: 1497:CLFO_RS13680
uniprot id: A0A1D9FQW8
names: Similarity
messages: Belongs to the peptidase S8 family.

1497:CLFO RS03845
gene id: 1497:CLFO_RS03845
uniprot id: A0A1D9FLB7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1497:CLFO RS00850
gene id: 1497:CLFO_RS00850
uniprot id: A0A1D9FJP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1497:CLFO RS09635
gene id: 1497:CLFO_RS09635
uniprot id: A0A1D9FNU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1497:CLFO RS17630
gene id: 1497:CLFO_RS17630
uniprot id: A0A1D9FHL6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1497:CLFO RS08935
gene id: 1497:CLFO_RS08935
uniprot id: A0A1D9FNJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1497:CLFO RS02265
gene id: 1497:CLFO_RS02265
uniprot id: A0A1D9FKW7
names: Similarity
messages: Belongs to the TrpF family.

1497:CLFO RS20435
gene id: 1497:CLFO_RS20435
uniprot id: A0A1D9FIL6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1497:CLFO RS02390
gene id: 1497:CLFO_RS02390
uniprot id: A0A1D9FKV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1497:CLFO RS20335
gene id: 1497:CLFO_RS20335
uniprot id: A0A1D9FIJ6
names: Similarity
messages: Belongs to the AOR/FOR family.

1497:CLFO RS08990
gene id: 1497:CLFO_RS08990
uniprot id: A0A1D9FT92
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1497:CLFO RS12455
gene id: 1497:CLFO_RS12455
uniprot id: A0A1D9FQ90
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS15660
gene id: 1497:CLFO_RS15660
uniprot id: A0A1D9FS69
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS00295
gene id: 1497:CLFO_RS00295
uniprot id: A0A1D9FJ69
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1497:CLFO RS09755
gene id: 1497:CLFO_RS09755
uniprot id: A0A1D9FNZ2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1497:CLFO RS08415
gene id: 1497:CLFO_RS08415
uniprot id: A0A1D9FNE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1497:CLFO RS21335
gene id: 1497:CLFO_RS21335
uniprot id: A0A1D9FJD3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1497:CLFO RS12945
gene id: 1497:CLFO_RS12945
uniprot id: A0A1D9FQK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1497:CLFO RS15595
gene id: 1497:CLFO_RS15595
uniprot id: A0A1D9FRW8
names: Similarity
messages: Belongs to the CvfB family.

1497:CLFO RS01120
gene id: 1497:CLFO_RS01120
uniprot id: A0A1D9FSC7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1497:CLFO RS15205
gene id: 1497:CLFO_RS15205
uniprot id: A0A1D9FRS4
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS02525
gene id: 1497:CLFO_RS02525
uniprot id: A0A1D9FKB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS19765
gene id: 1497:CLFO_RS19765
uniprot id: A0A1D9FIA6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1497:CLFO RS06515
gene id: 1497:CLFO_RS06515
uniprot id: A0A1D9FM83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1497:CLFO RS20110
gene id: 1497:CLFO_RS20110
uniprot id: A0A1D9FID1
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1497:CLFO RS02005
gene id: 1497:CLFO_RS02005
uniprot id: A0A1D9FKC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1497:CLFO RS10310
gene id: 1497:CLFO_RS10310
uniprot id: A0A1D9FPD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1497:CLFO RS06670
gene id: 1497:CLFO_RS06670
uniprot id: A0A1D9FMS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1497:CLFO RS08535
gene id: 1497:CLFO_RS08535
uniprot id: A0A1D9FNT3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1497:CLFO RS18080
gene id: 1497:CLFO_RS18080
uniprot id: A0A1D9FHU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1497:CLFO RS20685
gene id: 1497:CLFO_RS20685
uniprot id: A0A1D9FJ08
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS08980
gene id: 1497:CLFO_RS08980
uniprot id: A0A1D9FSM9
names: Similarity
messages: Belongs to the RecJ family.

1497:CLFO RS20555
gene id: 1497:CLFO_RS20555
uniprot id: A0A1D9FS77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1497:CLFO RS09820
gene id: 1497:CLFO_RS09820
uniprot id: A0A1D9FNW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1497:CLFO RS06480
gene id: 1497:CLFO_RS06480
uniprot id: A0A1D9FM70
names: Similarity
messages: Belongs to the RutC family.

1497:CLFO RS00980
gene id: 1497:CLFO_RS00980
uniprot id: A0A1D9FJW7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1497:CLFO RS00155
gene id: 1497:CLFO_RS00155
uniprot id: A0A1D9FJR4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1497:CLFO RS10985
gene id: 1497:CLFO_RS10985
uniprot id: A0A1D9FPP5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1497:CLFO RS06865
gene id: 1497:CLFO_RS06865
uniprot id: A0A1D9FMF8
names: Similarity
messages: Belongs to the glutamate synthase family.

1497:CLFO RS02300
gene id: 1497:CLFO_RS02300
uniprot id: A0A1D9FK76
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS20240
gene id: 1497:CLFO_RS20240
uniprot id: A0A1D9FJ87
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

1497:CLFO RS10925
gene id: 1497:CLFO_RS10925
uniprot id: A0A1D9FPK7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS19730
gene id: 1497:CLFO_RS19730
uniprot id: A0A1D9FI66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1497:CLFO RS02285
gene id: 1497:CLFO_RS02285
uniprot id: A0A1D9FKT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1497:CLFO RS18880
gene id: 1497:CLFO_RS18880
uniprot id: A0A1D9FSD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1497:CLFO RS06825
gene id: 1497:CLFO_RS06825
uniprot id: A0A1D9FMK5
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1497:CLFO RS02030
gene id: 1497:CLFO_RS02030
uniprot id: A0A1D9FSM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1497:CLFO RS01560
gene id: 1497:CLFO_RS01560
uniprot id: A0A1D9FKJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS15960
gene id: 1497:CLFO_RS15960
uniprot id: A0A1D9FGV1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1497:CLFO RS05425
gene id: 1497:CLFO_RS05425
uniprot id: A0A1D9FLT8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS13845
gene id: 1497:CLFO_RS13845
uniprot id: A0A1D9FQZ6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1497:CLFO RS20410
gene id: 1497:CLFO_RS20410
uniprot id: A0A1D9FIR1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS14280
gene id: 1497:CLFO_RS14280
uniprot id: A0A1D9FRA2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1497:CLFO RS20855
gene id: 1497:CLFO_RS20855
uniprot id: A0A1D9FIS5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS09995
gene id: 1497:CLFO_RS09995
uniprot id: A0A1D9FP08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1497:CLFO RS14615
gene id: 1497:CLFO_RS14615
uniprot id: A0A1D9FRF4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS02990
gene id: 1497:CLFO_RS02990
uniprot id: A0A1D9FKR2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS04975
gene id: 1497:CLFO_RS04975
uniprot id: A0A1D9FLK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxA family. PdxA2 subfamily.
messages: Catalyzes the NAD-dependent oxidation and subsequent decarboxylation of D-threonate 4-phosphate to produce dihydroxyacetone phosphate (DHAP).
messages: Homodimer.

1497:CLFO RS16500
gene id: 1497:CLFO_RS16500
uniprot id: A0A1D9FH29
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1497:CLFO RS05525
gene id: 1497:CLFO_RS05525
uniprot id: A0A1D9FLY3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1497:CLFO RS07255
gene id: 1497:CLFO_RS07255
uniprot id: A0A1D9FN63
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1497:CLFO RS09255
gene id: 1497:CLFO_RS09255
uniprot id: A0A1D9FNR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS00710
gene id: 1497:CLFO_RS00710
uniprot id: A0A1D9FJM1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1497:CLFO RS08540
gene id: 1497:CLFO_RS08540
uniprot id: A0A1D9FNL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1497:CLFO RS08625
gene id: 1497:CLFO_RS08625
uniprot id: A0A1D9FNJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS14955
gene id: 1497:CLFO_RS14955
uniprot id: A0A1D9FS59
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS06430
gene id: 1497:CLFO_RS06430
uniprot id: A0A1D9FMG2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS11255
gene id: 1497:CLFO_RS11255
uniprot id: A0A1D9FPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1497:CLFO RS20770
gene id: 1497:CLFO_RS20770
uniprot id: A0A1D9FIS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxA family. PdxA2 subfamily.
messages: Catalyzes the NAD-dependent oxidation and subsequent decarboxylation of D-threonate 4-phosphate to produce dihydroxyacetone phosphate (DHAP).
messages: Homodimer.

1497:CLFO RS05870
gene id: 1497:CLFO_RS05870
uniprot id: A0A1D9FSI5
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1497:CLFO RS01285
gene id: 1497:CLFO_RS01285
uniprot id: A0A1D9FJP1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1497:CLFO RS07920
gene id: 1497:CLFO_RS07920
uniprot id: A0A1D9FMY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1497:CLFO RS18425
gene id: 1497:CLFO_RS18425
uniprot id: A0A1D9FHT6
names: Subcellular Location Annotation
messages: Cytoplasm

1497:CLFO RS18585
gene id: 1497:CLFO_RS18585
uniprot id: A0A1D9FIF5
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS04090
gene id: 1497:CLFO_RS04090
uniprot id: A0A1D9FLI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1497:CLFO RS04510
gene id: 1497:CLFO_RS04510
uniprot id: A0A1D9FLD1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1497:CLFO RS11900
gene id: 1497:CLFO_RS11900
uniprot id: A0A1D9FQ63
names: Similarity
messages: Belongs to the manganese catalase family.

1497:CLFO RS19675
gene id: 1497:CLFO_RS19675
uniprot id: A0A1D9FI75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1497:CLFO RS00940
gene id: 1497:CLFO_RS00940
uniprot id: A0A1D9FJI2
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS12960
gene id: 1497:CLFO_RS12960
uniprot id: A0A1D9FQI0
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1497:CLFO RS18370
gene id: 1497:CLFO_RS18370
uniprot id: A0A1D9FHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS13445
gene id: 1497:CLFO_RS13445
uniprot id: A0A1D9FR29
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1497:CLFO RS06535
gene id: 1497:CLFO_RS06535
uniprot id: A0A1D9FM81
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1497:CLFO RS18050
gene id: 1497:CLFO_RS18050
uniprot id: A0A1D9FHH2
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1497:CLFO RS11450
gene id: 1497:CLFO_RS11450
uniprot id: A0A1D9FPT5
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1497:CLFO RS10070
gene id: 1497:CLFO_RS10070
uniprot id: A0A1D9FP21
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1497:CLFO RS12505
gene id: 1497:CLFO_RS12505
uniprot id: A0A1D9FQA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1497:CLFO RS16185
gene id: 1497:CLFO_RS16185
uniprot id: A0A1D9FGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS03065
gene id: 1497:CLFO_RS03065
uniprot id: A0A1D9FKM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1497:CLFO RS01930
gene id: 1497:CLFO_RS01930
uniprot id: A0A1D9FK38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1497:CLFO RS08915
gene id: 1497:CLFO_RS08915
uniprot id: A0A1D9FNG6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1497:CLFO RS08455
gene id: 1497:CLFO_RS08455
uniprot id: A0A1D9FSN6
names: Similarity
messages: Belongs to the UPF0758 family.

1497:CLFO RS03695
gene id: 1497:CLFO_RS03695
uniprot id: A0A1D9FL87
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS03085
gene id: 1497:CLFO_RS03085
uniprot id: A0A1D9FKM8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1497:CLFO RS19355
gene id: 1497:CLFO_RS19355
uniprot id: A0A1D9FI00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Spore core

1497:CLFO RS04265
gene id: 1497:CLFO_RS04265
uniprot id: A0A1D9FL96
names: Similarity
messages: Belongs to the thioredoxin family.

1497:CLFO RS12250
gene id: 1497:CLFO_RS12250
uniprot id: A0A1D9FQH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1497:CLFO RS18615
gene id: 1497:CLFO_RS18615
uniprot id: A0A1D9FIK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1497:CLFO RS04190
gene id: 1497:CLFO_RS04190
uniprot id: A0A1D9FLI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1497:CLFO RS00375
gene id: 1497:CLFO_RS00375
uniprot id: A0A1D9FJF9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1497:CLFO RS11355
gene id: 1497:CLFO_RS11355
uniprot id: A0A1D9FPY4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1497:CLFO RS01030
gene id: 1497:CLFO_RS01030
uniprot id: A0A1D9FK69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1497:CLFO RS14680
gene id: 1497:CLFO_RS14680
uniprot id: A0A1D9FRQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1497:CLFO RS11200
gene id: 1497:CLFO_RS11200
uniprot id: A0A1D9FPY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1497:CLFO RS09720
gene id: 1497:CLFO_RS09720
uniprot id: A0A1D9FNW3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1497:CLFO RS18055
gene id: 1497:CLFO_RS18055
uniprot id: A0A1D9FHJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1497:CLFO RS11185
gene id: 1497:CLFO_RS11185
uniprot id: A0A1D9FPN9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1497:CLFO RS19545
gene id: 1497:CLFO_RS19545
uniprot id: A0A1D9FIB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1497:CLFO RS00885
gene id: 1497:CLFO_RS00885
uniprot id: A0A1D9FK95
names: Similarity
messages: Belongs to the FBPase class 2 family.

1497:CLFO RS21995
gene id: 1497:CLFO_RS21995
uniprot id: A0A1D9FMI3
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

1497:CLFO RS11060
gene id: 1497:CLFO_RS11060
uniprot id: A0A1D9FPK3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS06435
gene id: 1497:CLFO_RS06435
uniprot id: A0A1D9FMD3
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS04765
gene id: 1497:CLFO_RS04765
uniprot id: A0A1D9FM43
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

1497:CLFO RS13495
gene id: 1497:CLFO_RS13495
uniprot id: A0A1D9FR30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1497:CLFO RS00865
gene id: 1497:CLFO_RS00865
uniprot id: A0A1D9FJK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1497:CLFO RS01670
gene id: 1497:CLFO_RS01670
uniprot id: A0A1D9FJY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1497:CLFO RS04640
gene id: 1497:CLFO_RS04640
uniprot id: A0A1D9FM23
names: Similarity
messages: Belongs to the glutamine synthetase family.

1497:CLFO RS05510
gene id: 1497:CLFO_RS05510
uniprot id: A0A1D9FSR1
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS18330
gene id: 1497:CLFO_RS18330
uniprot id: A0A1D9FHP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS03940
gene id: 1497:CLFO_RS03940
uniprot id: A0A1D9FL20
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1497:CLFO RS19755
gene id: 1497:CLFO_RS19755
uniprot id: A0A1D9FIU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1497:CLFO RS11955
gene id: 1497:CLFO_RS11955
uniprot id: A0A1D9FQ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

1497:CLFO RS05280
gene id: 1497:CLFO_RS05280
uniprot id: A0A1D9FMB6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1497:CLFO RS08320
gene id: 1497:CLFO_RS08320
uniprot id: A0A1D9FN60
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS07175
gene id: 1497:CLFO_RS07175
uniprot id: A0A1D9FMN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1497:CLFO RS18235
gene id: 1497:CLFO_RS18235
uniprot id: A0A1D9FID5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1497:CLFO RS19670
gene id: 1497:CLFO_RS19670
uniprot id: A0A1D9FI58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1497:CLFO RS10895
gene id: 1497:CLFO_RS10895
uniprot id: A0A1D9FPH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1497:CLFO RS01115
gene id: 1497:CLFO_RS01115
uniprot id: A0A1D9FJL1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1497:CLFO RS00840
gene id: 1497:CLFO_RS00840
uniprot id: A0A1D9FJS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1497:CLFO RS18065
gene id: 1497:CLFO_RS18065
uniprot id: A0A1D9FHI2
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1497:CLFO RS09450
gene id: 1497:CLFO_RS09450
uniprot id: A0A1D9FP23
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1497:CLFO RS07185
gene id: 1497:CLFO_RS07185
uniprot id: A0A1D9FML3
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS11080
gene id: 1497:CLFO_RS11080
uniprot id: A0A1D9FPL1
names: Similarity
messages: Belongs to the MotB family.

1497:CLFO RS19360
gene id: 1497:CLFO_RS19360
uniprot id: A0A1D9FIS2
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1497:CLFO RS01860
gene id: 1497:CLFO_RS01860
uniprot id: A0A1D9FK27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1497:CLFO RS18275
gene id: 1497:CLFO_RS18275
uniprot id: A0A1D9FHL3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1497:CLFO RS15915
gene id: 1497:CLFO_RS15915
uniprot id: A0A1D9FGI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS15430
gene id: 1497:CLFO_RS15430
uniprot id: A0A1D9FRW5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1497:CLFO RS12580
gene id: 1497:CLFO_RS12580
uniprot id: A0A1D9FQN4
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS12005
gene id: 1497:CLFO_RS12005
uniprot id: A0A1D9FQ79
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1497:CLFO RS20605
gene id: 1497:CLFO_RS20605
uniprot id: A0A1D9FIM2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1497:CLFO RS00275
gene id: 1497:CLFO_RS00275
uniprot id: A0A1D9FJD8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1497:CLFO RS17685
gene id: 1497:CLFO_RS17685
uniprot id: A0A1D9FHJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1497:CLFO RS01025
gene id: 1497:CLFO_RS01025
uniprot id: A0A1D9FJS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1497:CLFO RS05830
gene id: 1497:CLFO_RS05830
uniprot id: A0A1D9FM24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1497:CLFO RS05750
gene id: 1497:CLFO_RS05750
uniprot id: A0A1D9FLZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1497:CLFO RS02995
gene id: 1497:CLFO_RS02995
uniprot id: A0A1D9FL74
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1497:CLFO RS20740
gene id: 1497:CLFO_RS20740
uniprot id: A0A1D9FIW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1497:CLFO RS17810
gene id: 1497:CLFO_RS17810
uniprot id: A0A1D9FHK9
names: Similarity
messages: Belongs to the peptidase S16 family.

1497:CLFO RS05800
gene id: 1497:CLFO_RS05800
uniprot id: A0A1D9FML5
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS07065
gene id: 1497:CLFO_RS07065
uniprot id: A0A1D9FN30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS13695
gene id: 1497:CLFO_RS13695
uniprot id: A0A1D9FR19
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS11390
gene id: 1497:CLFO_RS11390
uniprot id: A0A1D9FPQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1497:CLFO RS20180
gene id: 1497:CLFO_RS20180
uniprot id: A0A1D9FSE9
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS04205
gene id: 1497:CLFO_RS04205
uniprot id: A0A1D9FLT9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS01095
gene id: 1497:CLFO_RS01095
uniprot id: A0A1D9FJN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1497:CLFO RS18220
gene id: 1497:CLFO_RS18220
uniprot id: A0A1D9FHK4
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1497:CLFO RS04360
gene id: 1497:CLFO_RS04360
uniprot id: A0A1D9FLN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1497:CLFO RS01870
gene id: 1497:CLFO_RS01870
uniprot id: A0A1D9FK28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1497:CLFO RS10290
gene id: 1497:CLFO_RS10290
uniprot id: A0A1D9FPQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1497:CLFO RS20300
gene id: 1497:CLFO_RS20300
uniprot id: A0A1D9FIU6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1497:CLFO RS10810
gene id: 1497:CLFO_RS10810
uniprot id: A0A1D9FPM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1497:CLFO RS16705
gene id: 1497:CLFO_RS16705
uniprot id: A0A1D9FGW3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1497:CLFO RS16485
gene id: 1497:CLFO_RS16485
uniprot id: A0A1D9FGQ0
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1497:CLFO RS05460
gene id: 1497:CLFO_RS05460
uniprot id: A0A1D9FLV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1497:CLFO RS12720
gene id: 1497:CLFO_RS12720
uniprot id: A0A1D9FQD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS11085
gene id: 1497:CLFO_RS11085
uniprot id: A0A1D9FPP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1497:CLFO RS04355
gene id: 1497:CLFO_RS04355
uniprot id: A0A1D9FLX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1497:CLFO RS18885
gene id: 1497:CLFO_RS18885
uniprot id: A0A1D9FHX6
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1497:CLFO RS04115
gene id: 1497:CLFO_RS04115
uniprot id: A0A1D9FLV8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS12780
gene id: 1497:CLFO_RS12780
uniprot id: A0A1D9FQL4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1497:CLFO RS03325
gene id: 1497:CLFO_RS03325
uniprot id: A0A1D9FL54
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1497:CLFO RS06615
gene id: 1497:CLFO_RS06615
uniprot id: A0A1D9FMB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1497:CLFO RS03865
gene id: 1497:CLFO_RS03865
uniprot id: A0A1D9FLE9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1497:CLFO RS20115
gene id: 1497:CLFO_RS20115
uniprot id: A0A1D9FJ67
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1497:CLFO RS11835
gene id: 1497:CLFO_RS11835
uniprot id: A0A1D9FQH5
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS20245
gene id: 1497:CLFO_RS20245
uniprot id: A0A1D9FIF9
names: Similarity
messages: Belongs to the UPF0173 family.

1497:CLFO RS03015
gene id: 1497:CLFO_RS03015
uniprot id: A0A1D9FKL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1497:CLFO RS16470
gene id: 1497:CLFO_RS16470
uniprot id: A0A1D9FGP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS04395
gene id: 1497:CLFO_RS04395
uniprot id: A0A1D9FLL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS11795
gene id: 1497:CLFO_RS11795
uniprot id: A0A1D9FQ45
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1497:CLFO RS10015
gene id: 1497:CLFO_RS10015
uniprot id: A0A1D9FP12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS09860
gene id: 1497:CLFO_RS09860
uniprot id: A0A1D9FP78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1497:CLFO RS09515
gene id: 1497:CLFO_RS09515
uniprot id: A0A1D9FP27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

1497:CLFO RS09850
gene id: 1497:CLFO_RS09850
uniprot id: A0A1D9FP59
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1497:CLFO RS12270
gene id: 1497:CLFO_RS12270
uniprot id: A0A1D9FQ84
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1497:CLFO RS22135
gene id: 1497:CLFO_RS22135
uniprot id: A0A1D9FK98
names: Similarity
messages: Belongs to the 'phage' integrase family.

1497:CLFO RS01140
gene id: 1497:CLFO_RS01140
uniprot id: A0A1D9FJX2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1497:CLFO RS00990
gene id: 1497:CLFO_RS00990
uniprot id: A0A1D9FJI8
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS04605
gene id: 1497:CLFO_RS04605
uniprot id: A0A1D9FLE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1497:CLFO RS15195
gene id: 1497:CLFO_RS15195
uniprot id: A0A1D9FRY2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS02615
gene id: 1497:CLFO_RS02615
uniprot id: A0A1D9FKR1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS04950
gene id: 1497:CLFO_RS04950
uniprot id: A0A1D9FLV7
names: Similarity
messages: Belongs to the DtxR/MntR family.

1497:CLFO RS19375
gene id: 1497:CLFO_RS19375
uniprot id: A0A1D9FI83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS11670
gene id: 1497:CLFO_RS11670
uniprot id: A0A1D9FPW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1497:CLFO RS02750
gene id: 1497:CLFO_RS02750
uniprot id: A0A1D9FKH4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1497:CLFO RS04840
gene id: 1497:CLFO_RS04840
uniprot id: A0A1D9FLP1
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

1497:CLFO RS12850
gene id: 1497:CLFO_RS12850
uniprot id: A0A1D9FQM4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1497:CLFO RS10130
gene id: 1497:CLFO_RS10130
uniprot id: A0A1D9FP80
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1497:CLFO RS14260
gene id: 1497:CLFO_RS14260
uniprot id: A0A1D9FRG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1497:CLFO RS13130
gene id: 1497:CLFO_RS13130
uniprot id: A0A1D9FQL2
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS02480
gene id: 1497:CLFO_RS02480
uniprot id: A0A1D9FKK3
names: Similarity
messages: Belongs to the HypE family.

1497:CLFO RS13995
gene id: 1497:CLFO_RS13995
uniprot id: A0A1D9FR33
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS19900
gene id: 1497:CLFO_RS19900
uniprot id: A0A1D9FIM3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1497:CLFO RS12930
gene id: 1497:CLFO_RS12930
uniprot id: A0A1D9FQU3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1497:CLFO RS21105
gene id: 1497:CLFO_RS21105
uniprot id: A0A1D9FJ33
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1497:CLFO RS00545
gene id: 1497:CLFO_RS00545
uniprot id: A0A1D9FJI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1497:CLFO RS04060
gene id: 1497:CLFO_RS04060
uniprot id: A0A1D9FL51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1497:CLFO RS07050
gene id: 1497:CLFO_RS07050
uniprot id: A0A1D9FML0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS18680
gene id: 1497:CLFO_RS18680
uniprot id: A0A1D9FI61
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS00315
gene id: 1497:CLFO_RS00315
uniprot id: A0A1D9FJ75
names: Similarity
messages: Belongs to the CobH/CbiC family.

1497:CLFO RS02270
gene id: 1497:CLFO_RS02270
uniprot id: A0A1D9FK64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1497:CLFO RS01395
gene id: 1497:CLFO_RS01395
uniprot id: A0A1D9FJR5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1497:CLFO RS03760
gene id: 1497:CLFO_RS03760
uniprot id: A0A1D9FLD3
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS15610
gene id: 1497:CLFO_RS15610
uniprot id: A0A1D9FS58
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS00790
gene id: 1497:CLFO_RS00790
uniprot id: A0A1D9FK30
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1497:CLFO RS13490
gene id: 1497:CLFO_RS13490
uniprot id: A0A1D9FR20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1497:CLFO RS16290
gene id: 1497:CLFO_RS16290
uniprot id: A0A1D9FGQ6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1497:CLFO RS11045
gene id: 1497:CLFO_RS11045
uniprot id: A0A1D9FPV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1497:CLFO RS12080
gene id: 1497:CLFO_RS12080
uniprot id: A0A1D9FQE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS02205
gene id: 1497:CLFO_RS02205
uniprot id: A0A1D9FK85
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1497:CLFO RS12655
gene id: 1497:CLFO_RS12655
uniprot id: A0A1D9FQF3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1497:CLFO RS11095
gene id: 1497:CLFO_RS11095
uniprot id: A0A1D9FPW7
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1497:CLFO RS13545
gene id: 1497:CLFO_RS13545
uniprot id: A0A1D9FR27
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS01600
gene id: 1497:CLFO_RS01600
uniprot id: A0A1D9FJV1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS02120
gene id: 1497:CLFO_RS02120
uniprot id: A0A1D9FKA9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1497:CLFO RS01290
gene id: 1497:CLFO_RS01290
uniprot id: A0A1D9FKE2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS15150
gene id: 1497:CLFO_RS15150
uniprot id: A0A1D9FRR8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1497:CLFO RS17670
gene id: 1497:CLFO_RS17670
uniprot id: A0A1D9FI21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1497:CLFO RS00870
gene id: 1497:CLFO_RS00870
uniprot id: A0A1D9FJG8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1497:CLFO RS08330
gene id: 1497:CLFO_RS08330
uniprot id: A0A1D9FN57
names: Similarity
messages: Belongs to the CdaR family.

1497:CLFO RS14945
gene id: 1497:CLFO_RS14945
uniprot id: A0A1D9FRK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS04015
gene id: 1497:CLFO_RS04015
uniprot id: A0A1D9FLU1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS12200
gene id: 1497:CLFO_RS12200
uniprot id: A0A1D9FQ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS06580
gene id: 1497:CLFO_RS06580
uniprot id: A0A1D9FMU9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS02010
gene id: 1497:CLFO_RS02010
uniprot id: A0A1D9FK96
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS10735
gene id: 1497:CLFO_RS10735
uniprot id: A0A1D9FPE7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1497:CLFO RS08410
gene id: 1497:CLFO_RS08410
uniprot id: A0A1D9FNF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1497:CLFO RS13750
gene id: 1497:CLFO_RS13750
uniprot id: A0A1D9FR73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1497:CLFO RS01845
gene id: 1497:CLFO_RS01845
uniprot id: A0A1D9FK67
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS15590
gene id: 1497:CLFO_RS15590
uniprot id: A0A1D9FSH1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1497:CLFO RS21100
gene id: 1497:CLFO_RS21100
uniprot id: A0A1D9FJ79
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1497:CLFO RS14435
gene id: 1497:CLFO_RS14435
uniprot id: A0A1D9FRD5
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1497:CLFO RS19705
gene id: 1497:CLFO_RS19705
uniprot id: A0A1D9FIT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1497:CLFO RS02580
gene id: 1497:CLFO_RS02580
uniprot id: A0A1D9FKD4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1497:CLFO RS17935
gene id: 1497:CLFO_RS17935
uniprot id: A0A1D9FHJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1497:CLFO RS01005
gene id: 1497:CLFO_RS01005
uniprot id: A0A1D9FJJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1497:CLFO RS01180
gene id: 1497:CLFO_RS01180
uniprot id: A0A1D9FKD1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1497:CLFO RS18190
gene id: 1497:CLFO_RS18190
uniprot id: A0A1D9FHX9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1497:CLFO RS14800
gene id: 1497:CLFO_RS14800
uniprot id: A0A1D9FRQ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS19630
gene id: 1497:CLFO_RS19630
uniprot id: A0A1D9FIX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1497:CLFO RS14385
gene id: 1497:CLFO_RS14385
uniprot id: A0A1D9FRA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS02515
gene id: 1497:CLFO_RS02515
uniprot id: A0A1D9FKC2
names: Similarity
messages: Belongs to the peptidase M29 family.

1497:CLFO RS13950
gene id: 1497:CLFO_RS13950
uniprot id: A0A1D9FR24
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS16545
gene id: 1497:CLFO_RS16545
uniprot id: A0A1D9FNE3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1497:CLFO RS08485
gene id: 1497:CLFO_RS08485
uniprot id: A0A1D9FSP3
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1497:CLFO RS08285
gene id: 1497:CLFO_RS08285
uniprot id: A0A1D9FNC2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1497:CLFO RS11150
gene id: 1497:CLFO_RS11150
uniprot id: A0A1D9FPX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1497:CLFO RS20020
gene id: 1497:CLFO_RS20020
uniprot id: A0A1D9FIB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1497:CLFO RS18375
gene id: 1497:CLFO_RS18375
uniprot id: A0A1D9FHN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS18205
gene id: 1497:CLFO_RS18205
uniprot id: A0A1D9FI03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1497:CLFO RS20485
gene id: 1497:CLFO_RS20485
uniprot id: A0A1D9FIK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1497:CLFO RS05500
gene id: 1497:CLFO_RS05500
uniprot id: A0A1D9FMG1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1497:CLFO RS20395
gene id: 1497:CLFO_RS20395
uniprot id: A0A1D9FJB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1497:CLFO RS18045
gene id: 1497:CLFO_RS18045
uniprot id: A0A1D9FHL1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1497:CLFO RS18335
gene id: 1497:CLFO_RS18335
uniprot id: A0A1D9FHP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS15655
gene id: 1497:CLFO_RS15655
uniprot id: A0A1D9FS66
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1497:CLFO RS11120
gene id: 1497:CLFO_RS11120
uniprot id: A0A1D9FPN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS00670
gene id: 1497:CLFO_RS00670
uniprot id: A0A1D9FJR6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1497:CLFO RS18520
gene id: 1497:CLFO_RS18520
uniprot id: A0A1D9FI60
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1497:CLFO RS15535
gene id: 1497:CLFO_RS15535
uniprot id: A0A1D9FSG1
names: Similarity
messages: Belongs to the EamA transporter family.

1497:CLFO RS11660
gene id: 1497:CLFO_RS11660
uniprot id: A0A1D9FQ61
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS13640
gene id: 1497:CLFO_RS13640
uniprot id: A0A1D9FQV6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS13155
gene id: 1497:CLFO_RS13155
uniprot id: A0A1D9FQS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1497:CLFO RS04100
gene id: 1497:CLFO_RS04100
uniprot id: A0A1D9FL48
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1497:CLFO RS05595
gene id: 1497:CLFO_RS05595
uniprot id: A0A1D9FM79
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1497:CLFO RS20505
gene id: 1497:CLFO_RS20505
uniprot id: A0A1D9FIL0
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1497:CLFO RS00005
gene id: 1497:CLFO_RS00005
uniprot id: A0A1D9FJ53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1497:CLFO RS18530
gene id: 1497:CLFO_RS18530
uniprot id: A0A1D9FHV6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1497:CLFO RS00900
gene id: 1497:CLFO_RS00900
uniprot id: A0A1D9FJQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1497:CLFO RS04900
gene id: 1497:CLFO_RS04900
uniprot id: A0A1D9FT38
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS01655
gene id: 1497:CLFO_RS01655
uniprot id: A0A1D9FK83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1497:CLFO RS03735
gene id: 1497:CLFO_RS03735
uniprot id: A0A1D9FLP4
names: Similarity
messages: Belongs to the UxaA family.

1497:CLFO RS12420
gene id: 1497:CLFO_RS12420
uniprot id: A0A1D9FQK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1497:CLFO RS06985
gene id: 1497:CLFO_RS06985
uniprot id: A0A1D9FN24
names: Similarity
messages: Belongs to the P(II) protein family.

1497:CLFO RS00530
gene id: 1497:CLFO_RS00530
uniprot id: A0A1D9FJB2
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1497:CLFO RS10990
gene id: 1497:CLFO_RS10990
uniprot id: A0A1D9FPV3
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1497:CLFO RS14350
gene id: 1497:CLFO_RS14350
uniprot id: A0A1D9FRD0
names: Similarity
messages: Belongs to the thioredoxin family.

1497:CLFO RS13010
gene id: 1497:CLFO_RS13010
uniprot id: A0A1D9FQI3
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS08930
gene id: 1497:CLFO_RS08930
uniprot id: A0A1D9FP01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1497:CLFO RS11500
gene id: 1497:CLFO_RS11500
uniprot id: A0A1D9FPU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1497:CLFO RS02280
gene id: 1497:CLFO_RS02280
uniprot id: A0A1D9FKE1
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1497:CLFO RS20885
gene id: 1497:CLFO_RS20885
uniprot id: A0A1D9FIV1
names: Similarity
messages: Belongs to the EamA transporter family.

1497:CLFO RS19570
gene id: 1497:CLFO_RS19570
uniprot id: A0A1D9FI57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1497:CLFO RS03075
gene id: 1497:CLFO_RS03075
uniprot id: A0A1D9FKN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1497:CLFO RS20235
gene id: 1497:CLFO_RS20235
uniprot id: A0A1D9FIF4
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1497:CLFO RS06990
gene id: 1497:CLFO_RS06990
uniprot id: A0A1D9FMY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1497:CLFO RS00515
gene id: 1497:CLFO_RS00515
uniprot id: A0A1D9FJA7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1497:CLFO RS11030
gene id: 1497:CLFO_RS11030
uniprot id: A0A1D9FPK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1497:CLFO RS00835
gene id: 1497:CLFO_RS00835
uniprot id: A0A1D9FSC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1497:CLFO RS18675
gene id: 1497:CLFO_RS18675
uniprot id: A0A1D9FHV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1497:CLFO RS18155
gene id: 1497:CLFO_RS18155
uniprot id: A0A1D9FHZ3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS02795
gene id: 1497:CLFO_RS02795
uniprot id: A0A1D9FKJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1497:CLFO RS11815
gene id: 1497:CLFO_RS11815
uniprot id: A0A1D9FQ29
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1497:CLFO RS10740
gene id: 1497:CLFO_RS10740
uniprot id: A0A1D9FPH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS09120
gene id: 1497:CLFO_RS09120
uniprot id: A0A1D9FNS9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1497:CLFO RS09645
gene id: 1497:CLFO_RS09645
uniprot id: A0A1D9FPD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1497:CLFO RS11725
gene id: 1497:CLFO_RS11725
uniprot id: A0A1D9FPX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS01715
gene id: 1497:CLFO_RS01715
uniprot id: A0A1D9FJW9
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS04160
gene id: 1497:CLFO_RS04160
uniprot id: A0A1D9FL83
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1497:CLFO RS14135
gene id: 1497:CLFO_RS14135
uniprot id: A0A1D9FR81
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1497:CLFO RS04165
gene id: 1497:CLFO_RS04165
uniprot id: A0A1D9FL77
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1497:CLFO RS20700
gene id: 1497:CLFO_RS20700
uniprot id: A0A1D9FJ32
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1497:CLFO RS18165
gene id: 1497:CLFO_RS18165
uniprot id: A0A1D9FHJ7
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS18435
gene id: 1497:CLFO_RS18435
uniprot id: A0A1D9FHS0
names: Subcellular Location Annotation
messages: Cytoplasm

1497:CLFO RS10180
gene id: 1497:CLFO_RS10180
uniprot id: A0A1D9FP36
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1497:CLFO RS20850
gene id: 1497:CLFO_RS20850
uniprot id: A0A1D9FJJ4
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

1497:CLFO RS20370
gene id: 1497:CLFO_RS20370
uniprot id: A0A1D9FIX3
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS08525
gene id: 1497:CLFO_RS08525
uniprot id: A0A1D9FNH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1497:CLFO RS11430
gene id: 1497:CLFO_RS11430
uniprot id: A0A1D9FQ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1497:CLFO RS05030
gene id: 1497:CLFO_RS05030
uniprot id: A0A1D9FLP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1497:CLFO RS11560
gene id: 1497:CLFO_RS11560
uniprot id: A0A1D9FQC6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1497:CLFO RS20255
gene id: 1497:CLFO_RS20255
uniprot id: A0A1D9FIN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1497:CLFO RS06755
gene id: 1497:CLFO_RS06755
uniprot id: A0A1D9FMD6
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS11035
gene id: 1497:CLFO_RS11035
uniprot id: A0A1D9FPN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1497:CLFO RS13150
gene id: 1497:CLFO_RS13150
uniprot id: A0A1D9FQY0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1497:CLFO RS10880
gene id: 1497:CLFO_RS10880
uniprot id: A0A1D9FPT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1497:CLFO RS17595
gene id: 1497:CLFO_RS17595
uniprot id: A0A1D9FHV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1497:CLFO RS11710
gene id: 1497:CLFO_RS11710
uniprot id: A0A1D9FQ69
names: Similarity
messages: Belongs to the UPF0749 family.

1497:CLFO RS07135
gene id: 1497:CLFO_RS07135
uniprot id: A0A1D9FMK6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

1497:CLFO RS02275
gene id: 1497:CLFO_RS02275
uniprot id: A0A1D9FKG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1497:CLFO RS03245
gene id: 1497:CLFO_RS03245
uniprot id: A0A1D9FKW1
names: Similarity
messages: Belongs to the UPF0045 family.

1497:CLFO RS00020
gene id: 1497:CLFO_RS00020
uniprot id: A0A1D9FJ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1497:CLFO RS00335
gene id: 1497:CLFO_RS00335
uniprot id: A0A1D9FJK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.

1497:CLFO RS18310
gene id: 1497:CLFO_RS18310
uniprot id: A0A1D9FIA7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1497:CLFO RS09830
gene id: 1497:CLFO_RS09830
uniprot id: A0A1D9FNW7
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1497:CLFO RS16830
gene id: 1497:CLFO_RS16830
uniprot id: A0A1D9FGV7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS04865
gene id: 1497:CLFO_RS04865
uniprot id: A0A1D9FLI5
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS11765
gene id: 1497:CLFO_RS11765
uniprot id: A0A1D9FQ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1497:CLFO RS10620
gene id: 1497:CLFO_RS10620
uniprot id: A0A1D9FPV6
names: Similarity
messages: Belongs to the peptidase S24 family.

1497:CLFO RS20570
gene id: 1497:CLFO_RS20570
uniprot id: A0A1D9FIZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1497:CLFO RS00460
gene id: 1497:CLFO_RS00460
uniprot id: A0A1D9FK24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1497:CLFO RS04240
gene id: 1497:CLFO_RS04240
uniprot id: A0A1D9FL71
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1497:CLFO RS05110
gene id: 1497:CLFO_RS05110
uniprot id: A0A1D9FLU5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1497:CLFO RS14925
gene id: 1497:CLFO_RS14925
uniprot id: A0A1D9FRT1
names: Similarity
messages: Belongs to the IlvD/Edd family.

1497:CLFO RS11755
gene id: 1497:CLFO_RS11755
uniprot id: A0A1D9FQ86
names: Similarity
messages: Belongs to the transpeptidase family.

1497:CLFO RS12875
gene id: 1497:CLFO_RS12875
uniprot id: A0A1D9FQI1
names: Similarity
messages: Belongs to the UPF0371 family.

1497:CLFO RS01355
gene id: 1497:CLFO_RS01355
uniprot id: A0A1D9FK12
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1497:CLFO RS06735
gene id: 1497:CLFO_RS06735
uniprot id: A0A1D9FMT2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1497:CLFO RS12800
gene id: 1497:CLFO_RS12800
uniprot id: A0A1D9FQS7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1497:CLFO RS16565
gene id: 1497:CLFO_RS16565
uniprot id: A0A1D9FH54
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1497:CLFO RS20375
gene id: 1497:CLFO_RS20375
uniprot id: A0A1D9FIL8
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1497:CLFO RS03585
gene id: 1497:CLFO_RS03585
uniprot id: A0A1D9FL16
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1497:CLFO RS09845
gene id: 1497:CLFO_RS09845
uniprot id: A0A1D9FP42
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1497:CLFO RS17895
gene id: 1497:CLFO_RS17895
uniprot id: A0A1D9FHG7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1497:CLFO RS15250
gene id: 1497:CLFO_RS15250
uniprot id: A0A1D9FRZ2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

1497:CLFO RS01895
gene id: 1497:CLFO_RS01895
uniprot id: A0A1D9FK79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

1497:CLFO RS21035
gene id: 1497:CLFO_RS21035
uniprot id: A0A1D9FJ68
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS00510
gene id: 1497:CLFO_RS00510
uniprot id: A0A1D9FJD7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1497:CLFO RS14320
gene id: 1497:CLFO_RS14320
uniprot id: A0A1D9FRI2
names: Similarity
messages: Belongs to the sigma-54 factor family.

1497:CLFO RS13765
gene id: 1497:CLFO_RS13765
uniprot id: A0A1D9FR25
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1497:CLFO RS18030
gene id: 1497:CLFO_RS18030
uniprot id: A0A1D9FHP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1497:CLFO RS15295
gene id: 1497:CLFO_RS15295
uniprot id: A0A1D9FRR9
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS03205
gene id: 1497:CLFO_RS03205
uniprot id: A0A1D9FL35
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1497:CLFO RS18040
gene id: 1497:CLFO_RS18040
uniprot id: A0A1D9FHW5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS02895
gene id: 1497:CLFO_RS02895
uniprot id: A0A1D9FKJ4
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

1497:CLFO RS09745
gene id: 1497:CLFO_RS09745
uniprot id: A0A1D9FPA4
names: Similarity
messages: Belongs to the TlyA family.

1497:CLFO RS16220
gene id: 1497:CLFO_RS16220
uniprot id: A0A1D9FGU6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1497:CLFO RS02585
gene id: 1497:CLFO_RS02585
uniprot id: A0A1D9FL22
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1497:CLFO RS12515
gene id: 1497:CLFO_RS12515
uniprot id: A0A1D9FQA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1497:CLFO RS19990
gene id: 1497:CLFO_RS19990
uniprot id: A0A1D9FIE2
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

1497:CLFO RS05360
gene id: 1497:CLFO_RS05360
uniprot id: A0A1D9FMF3
names: Similarity
messages: Belongs to the EamA transporter family.

1497:CLFO RS05390
gene id: 1497:CLFO_RS05390
uniprot id: A0A1D9FLU4
names: Subcellular Location Annotation
messages: Cytoplasm

1497:CLFO RS18890
gene id: 1497:CLFO_RS18890
uniprot id: A0A1D9FHZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1497:CLFO RS13835
gene id: 1497:CLFO_RS13835
uniprot id: A0A1D9FQZ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1497:CLFO RS17690
gene id: 1497:CLFO_RS17690
uniprot id: A0A1D9FHY0
names: Similarity
messages: Belongs to the peptidase S41A family.

1497:CLFO RS05795
gene id: 1497:CLFO_RS05795
uniprot id: A0A1D9FM13
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS11215
gene id: 1497:CLFO_RS11215
uniprot id: A0A1D9FPN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1497:CLFO RS01475
gene id: 1497:CLFO_RS01475
uniprot id: A0A1D9FKD7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1497:CLFO RS13665
gene id: 1497:CLFO_RS13665
uniprot id: A0A1D9FR12
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1497:CLFO RS10010
gene id: 1497:CLFO_RS10010
uniprot id: A0A1D9FPJ7
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS11410
gene id: 1497:CLFO_RS11410
uniprot id: A0A1D9FPV4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1497:CLFO RS04155
gene id: 1497:CLFO_RS04155
uniprot id: A0A1D9FL58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS20775
gene id: 1497:CLFO_RS20775
uniprot id: A0A1D9FIQ2
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1497:CLFO RS14240
gene id: 1497:CLFO_RS14240
uniprot id: A0A1D9FRT2
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1497:CLFO RS20400
gene id: 1497:CLFO_RS20400
uniprot id: A0A1D9FIJ0
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1497:CLFO RS01055
gene id: 1497:CLFO_RS01055
uniprot id: A0A1D9FJK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS06710
gene id: 1497:CLFO_RS06710
uniprot id: A0A1D9FMC8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS16155
gene id: 1497:CLFO_RS16155
uniprot id: A0A1D9FHA1
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1497:CLFO RS00370
gene id: 1497:CLFO_RS00370
uniprot id: A0A1D9FJJ7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1497:CLFO RS02450
gene id: 1497:CLFO_RS02450
uniprot id: A0A1D9FKA8
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1497:CLFO RS17435
gene id: 1497:CLFO_RS17435
uniprot id: A0A1D9FHS9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS09855
gene id: 1497:CLFO_RS09855
uniprot id: A0A1D9FPC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS10955
gene id: 1497:CLFO_RS10955
uniprot id: A0A1D9FPK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1497:CLFO RS22150
gene id: 1497:CLFO_RS22150
uniprot id: A0A1D9FM75
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

1497:CLFO RS00035
gene id: 1497:CLFO_RS00035
uniprot id: A0A1D9FJE9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1497:CLFO RS04990
gene id: 1497:CLFO_RS04990
uniprot id: A0A1D9FMA1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1497:CLFO RS08560
gene id: 1497:CLFO_RS08560
uniprot id: A0A1D9FNA4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1497:CLFO RS07830
gene id: 1497:CLFO_RS07830
uniprot id: A0A1D9FN71
names: Similarity
messages: Belongs to the UPF0178 family.

1497:CLFO RS03095
gene id: 1497:CLFO_RS03095
uniprot id: A0A1D9FKT1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS21235
gene id: 1497:CLFO_RS21235
uniprot id: A0A1D9FJC0
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1497:CLFO RS12400
gene id: 1497:CLFO_RS12400
uniprot id: A0A1D9FQS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1497:CLFO RS04230
gene id: 1497:CLFO_RS04230
uniprot id: A0A1D9FL86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1497:CLFO RS18270
gene id: 1497:CLFO_RS18270
uniprot id: A0A1D9FHQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1497:CLFO RS11720
gene id: 1497:CLFO_RS11720
uniprot id: A0A1D9FPX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS01110
gene id: 1497:CLFO_RS01110
uniprot id: A0A1D9FJN5
names: Similarity
messages: Belongs to the CpsD/CapB family.

1497:CLFO RS11745
gene id: 1497:CLFO_RS11745
uniprot id: A0A1D9FQ30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1497:CLFO RS20260
gene id: 1497:CLFO_RS20260
uniprot id: A0A1D9FJ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS11260
gene id: 1497:CLFO_RS11260
uniprot id: A0A1D9FPS8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1497:CLFO RS02065
gene id: 1497:CLFO_RS02065
uniprot id: A0A1D9FKC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS00080
gene id: 1497:CLFO_RS00080
uniprot id: A0A1D9FJG3
names: Similarity
messages: Belongs to the class-I fumarase family.

1497:CLFO RS15675
gene id: 1497:CLFO_RS15675
uniprot id: A0A1D9FRZ8
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS17660
gene id: 1497:CLFO_RS17660
uniprot id: A0A1D9FHX1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1497:CLFO RS01010
gene id: 1497:CLFO_RS01010
uniprot id: A0A1D9FKB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1497:CLFO RS19685
gene id: 1497:CLFO_RS19685
uniprot id: A0A1D9FIY5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1497:CLFO RS17940
gene id: 1497:CLFO_RS17940
uniprot id: A0A1D9FHF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS16540
gene id: 1497:CLFO_RS16540
uniprot id: A0A1D9FHH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).

1497:CLFO RS12285
gene id: 1497:CLFO_RS12285
uniprot id: A0A1D9FQ57
names: Similarity
messages: Belongs to the EamA transporter family.

1497:CLFO RS07170
gene id: 1497:CLFO_RS07170
uniprot id: A0A1D9FMK7
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1497:CLFO RS09835
gene id: 1497:CLFO_RS09835
uniprot id: A0A1D9FPG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1497:CLFO RS05760
gene id: 1497:CLFO_RS05760
uniprot id: A0A1D9FM66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1497:CLFO RS07215
gene id: 1497:CLFO_RS07215
uniprot id: A0A1D9FMN2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1497:CLFO RS20565
gene id: 1497:CLFO_RS20565
uniprot id: A0A1D9FIM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1497:CLFO RS12585
gene id: 1497:CLFO_RS12585
uniprot id: A0A1D9FQM5
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS03240
gene id: 1497:CLFO_RS03240
uniprot id: A0A1D9FL08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS14600
gene id: 1497:CLFO_RS14600
uniprot id: A0A1D9FRE5
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS00205
gene id: 1497:CLFO_RS00205
uniprot id: A0A1D9FJG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1497:CLFO RS02855
gene id: 1497:CLFO_RS02855
uniprot id: A0A1D9FKJ3
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

1497:CLFO RS22530
gene id: 1497:CLFO_RS22530
uniprot id: A0A1D9FK91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1497:CLFO RS11690
gene id: 1497:CLFO_RS11690
uniprot id: A0A1D9FPW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

1497:CLFO RS07150
gene id: 1497:CLFO_RS07150
uniprot id: A0A1D9FN48
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS21410
gene id: 1497:CLFO_RS21410
uniprot id: A0A1D9FJ16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1497:CLFO RS05045
gene id: 1497:CLFO_RS05045
uniprot id: A0A1D9FLK7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS08580
gene id: 1497:CLFO_RS08580
uniprot id: A0A1D9FNH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1497:CLFO RS03930
gene id: 1497:CLFO_RS03930
uniprot id: A0A1D9FLG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1497:CLFO RS05290
gene id: 1497:CLFO_RS05290
uniprot id: A0A1D9FLS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1497:CLFO RS05305
gene id: 1497:CLFO_RS05305
uniprot id: A0A1D9FLR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

1497:CLFO RS17550
gene id: 1497:CLFO_RS17550
uniprot id: A0A1D9FHC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1497:CLFO RS00880
gene id: 1497:CLFO_RS00880
uniprot id: A0A1D9FJH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1497:CLFO RS08450
gene id: 1497:CLFO_RS08450
uniprot id: A0A1D9FN81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1497:CLFO RS18515
gene id: 1497:CLFO_RS18515
uniprot id: A0A1D9FIE4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS00180
gene id: 1497:CLFO_RS00180
uniprot id: A0A1D9FJ49
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS11155
gene id: 1497:CLFO_RS11155
uniprot id: A0A1D9FPW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1497:CLFO RS00040
gene id: 1497:CLFO_RS00040
uniprot id: A0A1D9FJA2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1497:CLFO RS16405
gene id: 1497:CLFO_RS16405
uniprot id: A0A1D9FGN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1497:CLFO RS09195
gene id: 1497:CLFO_RS09195
uniprot id: A0A1D9FNQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1497:CLFO RS02035
gene id: 1497:CLFO_RS02035
uniprot id: A0A1D9FK58
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS00420
gene id: 1497:CLFO_RS00420
uniprot id: A0A1D9FJK5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1497:CLFO RS18195
gene id: 1497:CLFO_RS18195
uniprot id: A0A1D9FHT5
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1497:CLFO RS06810
gene id: 1497:CLFO_RS06810
uniprot id: A0A1D9FMY1
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1497:CLFO RS06400
gene id: 1497:CLFO_RS06400
uniprot id: A0A1D9FM72
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1497:CLFO RS19710
gene id: 1497:CLFO_RS19710
uniprot id: A0A1D9FIK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1497:CLFO RS06750
gene id: 1497:CLFO_RS06750
uniprot id: A0A1D9FME0
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS12390
gene id: 1497:CLFO_RS12390
uniprot id: A0A1D9FQ80
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1497:CLFO RS21340
gene id: 1497:CLFO_RS21340
uniprot id: A0A1D9FJ35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1497:CLFO RS14560
gene id: 1497:CLFO_RS14560
uniprot id: A0A1D9FRY9
names: Similarity
messages: Belongs to the KdgT transporter family.

1497:CLFO RS17560
gene id: 1497:CLFO_RS17560
uniprot id: A0A1D9FHA4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS17920
gene id: 1497:CLFO_RS17920
uniprot id: A0A1D9FHM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1497:CLFO RS05105
gene id: 1497:CLFO_RS05105
uniprot id: A0A1D9FLY2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS06590
gene id: 1497:CLFO_RS06590
uniprot id: A0A1D9FMK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BioW family.
messages: Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
messages: Homodimer.

1497:CLFO RS02545
gene id: 1497:CLFO_RS02545
uniprot id: A0A1D9FKX5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1497:CLFO RS18835
gene id: 1497:CLFO_RS18835
uniprot id: A0A1D9FIP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1497:CLFO RS09750
gene id: 1497:CLFO_RS09750
uniprot id: A0A1D9FP64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1497:CLFO RS19450
gene id: 1497:CLFO_RS19450
uniprot id: A0A1D9FIF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

1497:CLFO RS19635
gene id: 1497:CLFO_RS19635
uniprot id: A0A1D9FI45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1497:CLFO RS04070
gene id: 1497:CLFO_RS04070
uniprot id: A0A1D9FL43
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS02830
gene id: 1497:CLFO_RS02830
uniprot id: A0A1D9FL41
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1497:CLFO RS17570
gene id: 1497:CLFO_RS17570
uniprot id: A0A1D9FH86
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1497:CLFO RS03060
gene id: 1497:CLFO_RS03060
uniprot id: A0A1D9FKM2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1497:CLFO RS15190
gene id: 1497:CLFO_RS15190
uniprot id: A0A1D9FRY8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1497:CLFO RS05210
gene id: 1497:CLFO_RS05210
uniprot id: A0A1D9FMD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS09440
gene id: 1497:CLFO_RS09440
uniprot id: A0A1D9FSP4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1497:CLFO RS09190
gene id: 1497:CLFO_RS09190
uniprot id: A0A1D9FNY4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1497:CLFO RS16310
gene id: 1497:CLFO_RS16310
uniprot id: A0A1D9FHD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1497:CLFO RS00995
gene id: 1497:CLFO_RS00995
uniprot id: A0A1D9FJL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1497:CLFO RS05815
gene id: 1497:CLFO_RS05815
uniprot id: A0A1D9FM78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1497:CLFO RS01635
gene id: 1497:CLFO_RS01635
uniprot id: A0A1D9FSY4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS00735
gene id: 1497:CLFO_RS00735
uniprot id: A0A1D9FJH6
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1497:CLFO RS11180
gene id: 1497:CLFO_RS11180
uniprot id: A0A1D9FQ47
names: Similarity
messages: Belongs to the DprA/Smf family.

1497:CLFO RS10025
gene id: 1497:CLFO_RS10025
uniprot id: A0A1D9FSP2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1497:CLFO RS09695
gene id: 1497:CLFO_RS09695
uniprot id: A0A1D9FNY2
names: Similarity
messages: Belongs to the asp23 family.

1497:CLFO RS07200
gene id: 1497:CLFO_RS07200
uniprot id: A0A1D9FN53
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1497:CLFO RS10945
gene id: 1497:CLFO_RS10945
uniprot id: A0A1D9FPL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1497:CLFO RS11065
gene id: 1497:CLFO_RS11065
uniprot id: A0A1D9FPM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1497:CLFO RS21380
gene id: 1497:CLFO_RS21380
uniprot id: A0A1D9FJ82
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1497:CLFO RS00700
gene id: 1497:CLFO_RS00700
uniprot id: A0A1D9FJE0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1497:CLFO RS13525
gene id: 1497:CLFO_RS13525
uniprot id: A0A1D9FQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1497:CLFO RS11275
gene id: 1497:CLFO_RS11275
uniprot id: A0A1D9FPP2
names: Similarity
messages: Belongs to the fabD family.

1497:CLFO RS15620
gene id: 1497:CLFO_RS15620
uniprot id: A0A1D9FRZ6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS11440
gene id: 1497:CLFO_RS11440
uniprot id: A0A1D9FPS7
names: Similarity
messages: Belongs to the YicC/YloC family.

1497:CLFO RS11750
gene id: 1497:CLFO_RS11750
uniprot id: A0A1D9FQ52
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS15520
gene id: 1497:CLFO_RS15520
uniprot id: A0A1D9FRX3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1497:CLFO RS12625
gene id: 1497:CLFO_RS12625
uniprot id: A0A1D9FQM0
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS02245
gene id: 1497:CLFO_RS02245
uniprot id: A0A1D9FKA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1497:CLFO RS20625
gene id: 1497:CLFO_RS20625
uniprot id: A0A1D9FIV0
names: Similarity
messages: Belongs to the AOR/FOR family.

1497:CLFO RS04655
gene id: 1497:CLFO_RS04655
uniprot id: A0A1D9FLF3
names: Similarity
messages: Belongs to the peptidase C40 family.

1497:CLFO RS11485
gene id: 1497:CLFO_RS11485
uniprot id: A0A1D9FQ25
names: Subcellular Location Annotation
messages: Cytoplasm

1497:CLFO RS00795
gene id: 1497:CLFO_RS00795
uniprot id: A0A1D9FJT3
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS04350
gene id: 1497:CLFO_RS04350
uniprot id: A0A1D9FLG3
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1497:CLFO RS08255
gene id: 1497:CLFO_RS08255
uniprot id: A0A1D9FN46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1497:CLFO RS00285
gene id: 1497:CLFO_RS00285
uniprot id: A0A1D9FJJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1497:CLFO RS19425
gene id: 1497:CLFO_RS19425
uniprot id: A0A1D9FID2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1497:CLFO RS09340
gene id: 1497:CLFO_RS09340
uniprot id: A0A1D9FNQ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS00265
gene id: 1497:CLFO_RS00265
uniprot id: A0A1D9FJ65
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1497:CLFO RS02295
gene id: 1497:CLFO_RS02295
uniprot id: A0A1D9FKB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1497:CLFO RS04675
gene id: 1497:CLFO_RS04675
uniprot id: A0A1D9FM61
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS19565
gene id: 1497:CLFO_RS19565
uniprot id: A0A1D9FI38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1497:CLFO RS01345
gene id: 1497:CLFO_RS01345
uniprot id: A0A1D9FKF5
names: Similarity
messages: Belongs to the FlgM family.

1497:CLFO RS06830
gene id: 1497:CLFO_RS06830
uniprot id: A0A1D9FMZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1497:CLFO RS01885
gene id: 1497:CLFO_RS01885
uniprot id: A0A1D9FJZ6
names: Similarity
messages: Belongs to the asp23 family.

1497:CLFO RS09470
gene id: 1497:CLFO_RS09470
uniprot id: A0A1D9FNR8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS09290
gene id: 1497:CLFO_RS09290
uniprot id: A0A1D9FNV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1497:CLFO RS04780
gene id: 1497:CLFO_RS04780
uniprot id: A0A1D9FNE3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1497:CLFO RS05450
gene id: 1497:CLFO_RS05450
uniprot id: A0A1D9FMF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS00965
gene id: 1497:CLFO_RS00965
uniprot id: A0A1D9FJU2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1497:CLFO RS14125
gene id: 1497:CLFO_RS14125
uniprot id: A0A1D9FRQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS12975
gene id: 1497:CLFO_RS12975
uniprot id: A0A1D9FQU2
names: Similarity
messages: Belongs to the TelA family.

1497:CLFO RS11195
gene id: 1497:CLFO_RS11195
uniprot id: A0A1D9FPT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1497:CLFO RS11220
gene id: 1497:CLFO_RS11220
uniprot id: A0A1D9FPQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1497:CLFO RS09295
gene id: 1497:CLFO_RS09295
uniprot id: A0A1D9FP58
names: Similarity
messages: Belongs to the UPF0473 family.

1497:CLFO RS04615
gene id: 1497:CLFO_RS04615
uniprot id: A0A1D9FLF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Cytoplasm

1497:CLFO RS12085
gene id: 1497:CLFO_RS12085
uniprot id: A0A1D9FQE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1497:CLFO RS11405
gene id: 1497:CLFO_RS11405
uniprot id: A0A1D9FST2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1497:CLFO RS07945
gene id: 1497:CLFO_RS07945
uniprot id: A0A1D9FSU1
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

1497:CLFO RS02975
gene id: 1497:CLFO_RS02975
uniprot id: A0A1D9FKK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1497:CLFO RS13635
gene id: 1497:CLFO_RS13635
uniprot id: A0A1D9FRF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

1497:CLFO RS02910
gene id: 1497:CLFO_RS02910
uniprot id: A0A1D9FL89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS15450
gene id: 1497:CLFO_RS15450
uniprot id: A0A1D9FS22
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1497:CLFO RS05145
gene id: 1497:CLFO_RS05145
uniprot id: A0A1D9FLN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS01960
gene id: 1497:CLFO_RS01960
uniprot id: A0A1D9FK88
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1497:CLFO RS18400
gene id: 1497:CLFO_RS18400
uniprot id: A0A1D9FI15
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS19815
gene id: 1497:CLFO_RS19815
uniprot id: A0A1D9FIB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1497:CLFO RS12370
gene id: 1497:CLFO_RS12370
uniprot id: A0A1D9FQJ1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1497:CLFO RS18140
gene id: 1497:CLFO_RS18140
uniprot id: A0A1D9FHW8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS20475
gene id: 1497:CLFO_RS20475
uniprot id: A0A1D9FIZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1497:CLFO RS00075
gene id: 1497:CLFO_RS00075
uniprot id: A0A1D9FJQ6
names: Similarity
messages: Belongs to the class-I fumarase family.

1497:CLFO RS09910
gene id: 1497:CLFO_RS09910
uniprot id: A0A1D9FPD4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1497:CLFO RS00200
gene id: 1497:CLFO_RS00200
uniprot id: A0A1D9FJ54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1497:CLFO RS20780
gene id: 1497:CLFO_RS20780
uniprot id: A0A1D9FSH8
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS07180
gene id: 1497:CLFO_RS07180
uniprot id: A0A1D9FN49
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS05490
gene id: 1497:CLFO_RS05490
uniprot id: A0A1D9FM49
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS03125
gene id: 1497:CLFO_RS03125
uniprot id: A0A1D9FKP7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS09315
gene id: 1497:CLFO_RS09315
uniprot id: A0A1D9FSM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1497:CLFO RS16415
gene id: 1497:CLFO_RS16415
uniprot id: A0A1D9FGR6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS02770
gene id: 1497:CLFO_RS02770
uniprot id: A0A1D9FKM7
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS11010
gene id: 1497:CLFO_RS11010
uniprot id: A0A1D9FPJ3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1497:CLFO RS06370
gene id: 1497:CLFO_RS06370
uniprot id: A0A1D9FM50
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1497:CLFO RS22080
gene id: 1497:CLFO_RS22080
uniprot id: A0A1D9FGP7
names: Similarity
messages: Belongs to the peptidase S8 family.

1497:CLFO RS20690
gene id: 1497:CLFO_RS20690
uniprot id: A0A1D9FIV8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS12450
gene id: 1497:CLFO_RS12450
uniprot id: A0A1D9FQB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.

1497:CLFO RS02500
gene id: 1497:CLFO_RS02500
uniprot id: A0A1D9FKD0
names: Similarity
messages: Belongs to the GerABKA family.

1497:CLFO RS19965
gene id: 1497:CLFO_RS19965
uniprot id: A0A1D9FIA5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1497:CLFO RS12865
gene id: 1497:CLFO_RS12865
uniprot id: A0A1D9FQT3
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1497:CLFO RS01585
gene id: 1497:CLFO_RS01585
uniprot id: A0A1D9FKF1
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1497:CLFO RS20675
gene id: 1497:CLFO_RS20675
uniprot id: A0A1D9FIP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS11860
gene id: 1497:CLFO_RS11860
uniprot id: A0A1D9FQ97
names: Similarity
messages: Belongs to the ThiD family.

1497:CLFO RS20060
gene id: 1497:CLFO_RS20060
uniprot id: A0A1D9FIC2
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1497:CLFO RS06475
gene id: 1497:CLFO_RS06475
uniprot id: A0A1D9FMT0
names: Similarity
messages: Belongs to the UPF0597 family.

1497:CLFO RS13860
gene id: 1497:CLFO_RS13860
uniprot id: A0A1D9FQZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1497:CLFO RS11175
gene id: 1497:CLFO_RS11175
uniprot id: A0A1D9FPM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1497:CLFO RS18830
gene id: 1497:CLFO_RS18830
uniprot id: A0A1D9FHX0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1497:CLFO RS11985
gene id: 1497:CLFO_RS11985
uniprot id: A0A1D9FQ21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1497:CLFO RS05700
gene id: 1497:CLFO_RS05700
uniprot id: A0A1D9FM97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1497:CLFO RS11790
gene id: 1497:CLFO_RS11790
uniprot id: A0A1D9FPY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1497:CLFO RS02320
gene id: 1497:CLFO_RS02320
uniprot id: A0A1D9FKY2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1497:CLFO RS19700
gene id: 1497:CLFO_RS19700
uniprot id: A0A1D9FIE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1497:CLFO RS06600
gene id: 1497:CLFO_RS06600
uniprot id: A0A1D9FMV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS19650
gene id: 1497:CLFO_RS19650
uniprot id: A0A1D9FIT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1497:CLFO RS16365
gene id: 1497:CLFO_RS16365
uniprot id: A0A1D9FGQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1497:CLFO RS15185
gene id: 1497:CLFO_RS15185
uniprot id: A0A1D9FRX9
names: Similarity
messages: Belongs to the GcvT family.

1497:CLFO RS04600
gene id: 1497:CLFO_RS04600
uniprot id: A0A1D9FLF2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS18295
gene id: 1497:CLFO_RS18295
uniprot id: A0A1D9FHN6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1497:CLFO RS04960
gene id: 1497:CLFO_RS04960
uniprot id: A0A1D9FM71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1497:CLFO RS19605
gene id: 1497:CLFO_RS19605
uniprot id: A0A1D9FII9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1497:CLFO RS03945
gene id: 1497:CLFO_RS03945
uniprot id: A0A1D9FL46
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1497:CLFO RS15235
gene id: 1497:CLFO_RS15235
uniprot id: A0A1D9FSZ5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1497:CLFO RS14130
gene id: 1497:CLFO_RS14130
uniprot id: A0A1D9FR66
names: Function
names: Similarity
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

1497:CLFO RS17430
gene id: 1497:CLFO_RS17430
uniprot id: A0A1D9FHE5
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1497:CLFO RS19625
gene id: 1497:CLFO_RS19625
uniprot id: A0A1D9FI46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1497:CLFO RS01035
gene id: 1497:CLFO_RS01035
uniprot id: A0A1D9FJX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1497:CLFO RS19640
gene id: 1497:CLFO_RS19640
uniprot id: A0A1D9FIH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1497:CLFO RS05650
gene id: 1497:CLFO_RS05650
uniprot id: A0A1D9FM88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1497:CLFO RS19775
gene id: 1497:CLFO_RS19775
uniprot id: A0A1D9FI99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1497:CLFO RS10260
gene id: 1497:CLFO_RS10260
uniprot id: A0A1D9FPE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1497:CLFO RS08370
gene id: 1497:CLFO_RS08370
uniprot id: A0A1D9FNB3
names: Similarity
messages: Belongs to the peptidase C40 family.

1497:CLFO RS02255
gene id: 1497:CLFO_RS02255
uniprot id: A0A1D9FK97
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS03525
gene id: 1497:CLFO_RS03525
uniprot id: A0A1D9FKV0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1497:CLFO RS12965
gene id: 1497:CLFO_RS12965
uniprot id: A0A1D9FQP2
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1497:CLFO RS01015
gene id: 1497:CLFO_RS01015
uniprot id: A0A1D9FJJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1497:CLFO RS19720
gene id: 1497:CLFO_RS19720
uniprot id: A0A1D9FI65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1497:CLFO RS14715
gene id: 1497:CLFO_RS14715
uniprot id: A0A1D9FRG8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1497:CLFO RS08965
gene id: 1497:CLFO_RS08965
uniprot id: A0A1D9FNH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1497:CLFO RS11140
gene id: 1497:CLFO_RS11140
uniprot id: A0A1D9FPQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1497:CLFO RS11290
gene id: 1497:CLFO_RS11290
uniprot id: A0A1D9FPU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1497:CLFO RS00970
gene id: 1497:CLFO_RS00970
uniprot id: A0A1D9FJR0
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1497:CLFO RS15645
gene id: 1497:CLFO_RS15645
uniprot id: A0A1D9FRY3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS16130
gene id: 1497:CLFO_RS16130
uniprot id: A0A1D9FGX9
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS17905
gene id: 1497:CLFO_RS17905
uniprot id: A0A1D9FI62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1497:CLFO RS17995
gene id: 1497:CLFO_RS17995
uniprot id: A0A1D9FHG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1497:CLFO RS00130
gene id: 1497:CLFO_RS00130
uniprot id: A0A1D9FJB3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS20095
gene id: 1497:CLFO_RS20095
uniprot id: A0A1D9FIG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1497:CLFO RS11170
gene id: 1497:CLFO_RS11170
uniprot id: A0A1D9FPP4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1497:CLFO RS16975
gene id: 1497:CLFO_RS16975
uniprot id: A0A1D9FNE3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1497:CLFO RS14565
gene id: 1497:CLFO_RS14565
uniprot id: A0A1D9FRE7
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1497:CLFO RS00010
gene id: 1497:CLFO_RS00010
uniprot id: A0A1D9FJ28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1497:CLFO RS15515
gene id: 1497:CLFO_RS15515
uniprot id: A0A1D9FRX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1497:CLFO RS11225
gene id: 1497:CLFO_RS11225
uniprot id: A0A1D9FPN5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1497:CLFO RS03840
gene id: 1497:CLFO_RS03840
uniprot id: A0A1D9FL06
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS11950
gene id: 1497:CLFO_RS11950
uniprot id: A0A1D9FQ12
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS11810
gene id: 1497:CLFO_RS11810
uniprot id: A0A1D9FQ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1497:CLFO RS21085
gene id: 1497:CLFO_RS21085
uniprot id: A0A1D9FJN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1497:CLFO RS07130
gene id: 1497:CLFO_RS07130
uniprot id: A0A1D9FN40
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

1497:CLFO RS15870
gene id: 1497:CLFO_RS15870
uniprot id: A0A1D9FGH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS07570
gene id: 1497:CLFO_RS07570
uniprot id: A0A1D9FSM4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1497:CLFO RS14635
gene id: 1497:CLFO_RS14635
uniprot id: A0A1D9FRN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1497:CLFO RS04895
gene id: 1497:CLFO_RS04895
uniprot id: A0A1D9FLQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1497:CLFO RS07070
gene id: 1497:CLFO_RS07070
uniprot id: A0A1D9FMJ6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1497:CLFO RS07915
gene id: 1497:CLFO_RS07915
uniprot id: A0A1D9FMZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1497:CLFO RS09160
gene id: 1497:CLFO_RS09160
uniprot id: A0A1D9FP26
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1497:CLFO RS10860
gene id: 1497:CLFO_RS10860
uniprot id: A0A1D9FPH1
names: Similarity
messages: Belongs to the ribF family.

1497:CLFO RS16715
gene id: 1497:CLFO_RS16715
uniprot id: A0A1D9FH67
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS03740
gene id: 1497:CLFO_RS03740
uniprot id: A0A1D9FKY6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1497:CLFO RS20350
gene id: 1497:CLFO_RS20350
uniprot id: A0A1D9FIH8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1497:CLFO RS17640
gene id: 1497:CLFO_RS17640
uniprot id: A0A1D9FHX1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1497:CLFO RS09825
gene id: 1497:CLFO_RS09825
uniprot id: A0A1D9FNX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1497:CLFO RS08715
gene id: 1497:CLFO_RS08715
uniprot id: A0A1D9FNE3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1497:CLFO RS02260
gene id: 1497:CLFO_RS02260
uniprot id: A0A1D9FK78
names: Similarity
messages: Belongs to the TrpC family.

1497:CLFO RS02025
gene id: 1497:CLFO_RS02025
uniprot id: A0A1D9FKG1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1497:CLFO RS11760
gene id: 1497:CLFO_RS11760
uniprot id: A0A1D9FQ78
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS00925
gene id: 1497:CLFO_RS00925
uniprot id: A0A1D9FJH8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1497:CLFO RS19310
gene id: 1497:CLFO_RS19310
uniprot id: A0A1D9FIR3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1497:CLFO RS20365
gene id: 1497:CLFO_RS20365
uniprot id: A0A1D9FJ61
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS17925
gene id: 1497:CLFO_RS17925
uniprot id: A0A1D9FI23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1497:CLFO RS17115
gene id: 1497:CLFO_RS17115
uniprot id: A0A1D9FGZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1497:CLFO RS04595
gene id: 1497:CLFO_RS04595
uniprot id: A0A1D9FLS3
names: Similarity
messages: Belongs to the AOR/FOR family.

1497:CLFO RS16490
gene id: 1497:CLFO_RS16490
uniprot id: A0A1D9FHG2
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1497:CLFO RS00745
gene id: 1497:CLFO_RS00745
uniprot id: A0A1D9FK82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1497:CLFO RS08970
gene id: 1497:CLFO_RS08970
uniprot id: A0A1D9FNJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1497:CLFO RS17805
gene id: 1497:CLFO_RS17805
uniprot id: A0A1D9FHP4
names: Similarity
messages: Belongs to the leucine-binding protein family.

1497:CLFO RS03530
gene id: 1497:CLFO_RS03530
uniprot id: A0A1D9FL57
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1497:CLFO RS06450
gene id: 1497:CLFO_RS06450
uniprot id: A0A1D9FM73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1497:CLFO RS11615
gene id: 1497:CLFO_RS11615
uniprot id: A0A1D9FPV7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1497:CLFO RS18685
gene id: 1497:CLFO_RS18685
uniprot id: A0A1D9FI24
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS15695
gene id: 1497:CLFO_RS15695
uniprot id: A0A1D9FSI7
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

1497:CLFO RS11535
gene id: 1497:CLFO_RS11535
uniprot id: A0A1D9FQ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1497:CLFO RS08610
gene id: 1497:CLFO_RS08610
uniprot id: A0A1D9FNB8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1497:CLFO RS08470
gene id: 1497:CLFO_RS08470
uniprot id: A0A1D9FNG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1497:CLFO RS09710
gene id: 1497:CLFO_RS09710
uniprot id: A0A1D9FNU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1497:CLFO RS21000
gene id: 1497:CLFO_RS21000
uniprot id: A0A1D9FJ81
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS09485
gene id: 1497:CLFO_RS09485
uniprot id: A0A1D9FNR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS19555
gene id: 1497:CLFO_RS19555
uniprot id: A0A1D9FII0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1497:CLFO RS15485
gene id: 1497:CLFO_RS15485
uniprot id: A0A1D9FSF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1497:CLFO RS09305
gene id: 1497:CLFO_RS09305
uniprot id: A0A1D9FNS2
names: Similarity
messages: Belongs to the SfsA family.

1497:CLFO RS14305
gene id: 1497:CLFO_RS14305
uniprot id: A0A1D9FRC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1497:CLFO RS15315
gene id: 1497:CLFO_RS15315
uniprot id: A0A1D9FS09
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1497:CLFO RS12115
gene id: 1497:CLFO_RS12115
uniprot id: A0A1D9FQ36
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1497:CLFO RS05180
gene id: 1497:CLFO_RS05180
uniprot id: A0A1D9FM21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS03395
gene id: 1497:CLFO_RS03395
uniprot id: A0A1D9FKS4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1497:CLFO RS11840
gene id: 1497:CLFO_RS11840
uniprot id: A0A1D9FPZ5
names: Similarity
messages: Belongs to the cytochrome c-552 family.

1497:CLFO RS03610
gene id: 1497:CLFO_RS03610
uniprot id: A0A1D9FKW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS19930
gene id: 1497:CLFO_RS19930
uniprot id: A0A1D9FIA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1497:CLFO RS19665
gene id: 1497:CLFO_RS19665
uniprot id: A0A1D9FI88
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1497:CLFO RS06610
gene id: 1497:CLFO_RS06610
uniprot id: A0A1D9FMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1497:CLFO RS10240
gene id: 1497:CLFO_RS10240
uniprot id: A0A1D9FP51
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1497:CLFO RS20825
gene id: 1497:CLFO_RS20825
uniprot id: A0A1D9FSA2
names: Similarity
messages: Belongs to the IlvD/Edd family.

1497:CLFO RS10300
gene id: 1497:CLFO_RS10300
uniprot id: A0A1D9FPA2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1497:CLFO RS02920
gene id: 1497:CLFO_RS02920
uniprot id: A0A1D9FSF2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS01965
gene id: 1497:CLFO_RS01965
uniprot id: A0A1D9FKM5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1497:CLFO RS14400
gene id: 1497:CLFO_RS14400
uniprot id: A0A1D9FRC0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1497:CLFO RS15090
gene id: 1497:CLFO_RS15090
uniprot id: A0A1D9FRX1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1497:CLFO RS08575
gene id: 1497:CLFO_RS08575
uniprot id: A0A1D9FNI0
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS15210
gene id: 1497:CLFO_RS15210
uniprot id: A0A1D9FRP8
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS05315
gene id: 1497:CLFO_RS05315
uniprot id: A0A1D9FLQ8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1497:CLFO RS11070
gene id: 1497:CLFO_RS11070
uniprot id: A0A1D9FPK0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1497:CLFO RS12770
gene id: 1497:CLFO_RS12770
uniprot id: A0A1D9FR09
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1497:CLFO RS19595
gene id: 1497:CLFO_RS19595
uniprot id: A0A1D9FIC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1497:CLFO RS21040
gene id: 1497:CLFO_RS21040
uniprot id: A0A1D9FJ23
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS05060
gene id: 1497:CLFO_RS05060
uniprot id: A0A1D9FLT5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1497:CLFO RS13880
gene id: 1497:CLFO_RS13880
uniprot id: A0A1D9FR86
names: Similarity
messages: Belongs to the class-D beta-lactamase family.
messages: Belongs to the peptidase M56 family.

1497:CLFO RS08880
gene id: 1497:CLFO_RS08880
uniprot id: A0A1D9FNH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1497:CLFO RS18700
gene id: 1497:CLFO_RS18700
uniprot id: A0A1D9FHY1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1497:CLFO RS07000
gene id: 1497:CLFO_RS07000
uniprot id: A0A1D9FMK4
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1497:CLFO RS13885
gene id: 1497:CLFO_RS13885
uniprot id: A0A1D9FR38
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1497:CLFO RS19535
gene id: 1497:CLFO_RS19535
uniprot id: A0A1D9FI27
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS08295
gene id: 1497:CLFO_RS08295
uniprot id: A0A1D9FNN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1497:CLFO RS14035
gene id: 1497:CLFO_RS14035
uniprot id: A0A1D9FRB6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1497:CLFO RS13005
gene id: 1497:CLFO_RS13005
uniprot id: A0A1D9FR61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1497:CLFO RS13360
gene id: 1497:CLFO_RS13360
uniprot id: A0A1D9FQP9
names: Similarity
messages: Belongs to the creatininase superfamily.

1497:CLFO RS21055
gene id: 1497:CLFO_RS21055
uniprot id: A0A1D9FIY4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS04095
gene id: 1497:CLFO_RS04095
uniprot id: A0A1D9FL65
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1497:CLFO RS20105
gene id: 1497:CLFO_RS20105
uniprot id: A0A1D9FIF7
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

1497:CLFO RS17825
gene id: 1497:CLFO_RS17825
uniprot id: A0A1D9FHS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS16530
gene id: 1497:CLFO_RS16530
uniprot id: A0A1D9FGT6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1497:CLFO RS16195
gene id: 1497:CLFO_RS16195
uniprot id: A0A1D9FGM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS01660
gene id: 1497:CLFO_RS01660
uniprot id: A0A1D9FJY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1497:CLFO RS18100
gene id: 1497:CLFO_RS18100
uniprot id: A0A1D9FHN1
names: Similarity
messages: Belongs to the Ahb/Nir family.

1497:CLFO RS00535
gene id: 1497:CLFO_RS00535
uniprot id: A0A1D9FJM7
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1497:CLFO RS00550
gene id: 1497:CLFO_RS00550
uniprot id: A0A1D9FJY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1497:CLFO RS18630
gene id: 1497:CLFO_RS18630
uniprot id: A0A1D9FI14
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1497:CLFO RS12035
gene id: 1497:CLFO_RS12035
uniprot id: A0A1D9FQ46
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1497:CLFO RS04465
gene id: 1497:CLFO_RS04465
uniprot id: A0A1D9FLI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1497:CLFO RS20600
gene id: 1497:CLFO_RS20600
uniprot id: A0A1D9FIP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1497:CLFO RS10055
gene id: 1497:CLFO_RS10055
uniprot id: A0A1D9FP22
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1497:CLFO RS06505
gene id: 1497:CLFO_RS06505
uniprot id: A0A1D9FMP8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1497:CLFO RS16560
gene id: 1497:CLFO_RS16560
uniprot id: A0A1D9FHC9
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1497:CLFO RS11965
gene id: 1497:CLFO_RS11965
uniprot id: A0A1D9FQC4
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1497:CLFO RS20210
gene id: 1497:CLFO_RS20210
uniprot id: A0A1D9FII6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1497:CLFO RS00255
gene id: 1497:CLFO_RS00255
uniprot id: A0A1D9FJ56
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1497:CLFO RS08460
gene id: 1497:CLFO_RS08460
uniprot id: A0A1D9FNN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1497:CLFO RS05160
gene id: 1497:CLFO_RS05160
uniprot id: A0A1D9FLM9
names: Similarity
messages: Belongs to the manganese catalase family.

1497:CLFO RS20190
gene id: 1497:CLFO_RS20190
uniprot id: A0A1D9FIM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1497:CLFO RS05300
gene id: 1497:CLFO_RS05300
uniprot id: A0A1D9FLU3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1497:CLFO RS19750
gene id: 1497:CLFO_RS19750
uniprot id: A0A1D9FIF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1497:CLFO RS07940
gene id: 1497:CLFO_RS07940
uniprot id: A0A1D9FMY5
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

1497:CLFO RS17990
gene id: 1497:CLFO_RS17990
uniprot id: A0A1D9FHK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS09275
gene id: 1497:CLFO_RS09275
uniprot id: A0A1D9FP46
names: Similarity
messages: Belongs to the UPF0297 family.

1497:CLFO RS08275
gene id: 1497:CLFO_RS08275
uniprot id: A0A1D9FN39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS00185
gene id: 1497:CLFO_RS00185
uniprot id: A0A1D9FJ72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1497:CLFO RS14290
gene id: 1497:CLFO_RS14290
uniprot id: A0A1D9FR91
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1497:CLFO RS09530
gene id: 1497:CLFO_RS09530
uniprot id: A0A1D9FNS7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1497:CLFO RS20035
gene id: 1497:CLFO_RS20035
uniprot id: A0A1D9FJ04
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1497:CLFO RS13905
gene id: 1497:CLFO_RS13905
uniprot id: A0A1D9FRL2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1497:CLFO RS07040
gene id: 1497:CLFO_RS07040
uniprot id: A0A1D9FMZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1497:CLFO RS15300
gene id: 1497:CLFO_RS15300
uniprot id: A0A1D9FRU0
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS03885
gene id: 1497:CLFO_RS03885
uniprot id: A0A1D9FL34
names: Similarity
messages: Belongs to the IlvD/Edd family.

1497:CLFO RS03070
gene id: 1497:CLFO_RS03070
uniprot id: A0A1D9FKP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1497:CLFO RS08905
gene id: 1497:CLFO_RS08905
uniprot id: A0A1D9FNT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1497:CLFO RS04450
gene id: 1497:CLFO_RS04450
uniprot id: A0A1D9FLA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1497:CLFO RS02355
gene id: 1497:CLFO_RS02355
uniprot id: A0A1D9FK90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1497:CLFO RS18135
gene id: 1497:CLFO_RS18135
uniprot id: A0A1D9FHK8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS05615
gene id: 1497:CLFO_RS05615
uniprot id: A0A1D9FLY7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1497:CLFO RS04410
gene id: 1497:CLFO_RS04410
uniprot id: A0A1D9FLH2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1497:CLFO RS14315
gene id: 1497:CLFO_RS14315
uniprot id: A0A1D9FSZ3
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1497:CLFO RS08435
gene id: 1497:CLFO_RS08435
uniprot id: A0A1D9FNC3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1497:CLFO RS18185
gene id: 1497:CLFO_RS18185
uniprot id: A0A1D9FHL7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1497:CLFO RS13990
gene id: 1497:CLFO_RS13990
uniprot id: A0A1D9FR52
names: Subcellular Location Annotation
messages: Cytoplasm

1497:CLFO RS10815
gene id: 1497:CLFO_RS10815
uniprot id: A0A1D9FPS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1497:CLFO RS11770
gene id: 1497:CLFO_RS11770
uniprot id: A0A1D9FPX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1497:CLFO RS00175
gene id: 1497:CLFO_RS00175
uniprot id: A0A1D9FJ73
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1497:CLFO RS04650
gene id: 1497:CLFO_RS04650
uniprot id: A0A1D9FLF8
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS18485
gene id: 1497:CLFO_RS18485
uniprot id: A0A1D9FHT0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1497:CLFO RS18845
gene id: 1497:CLFO_RS18845
uniprot id: A0A1D9FI91
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1497:CLFO RS02220
gene id: 1497:CLFO_RS02220
uniprot id: A0A1D9FK56
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1497:CLFO RS17335
gene id: 1497:CLFO_RS17335
uniprot id: A0A1D9FH80
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1497:CLFO RS03035
gene id: 1497:CLFO_RS03035
uniprot id: A0A1D9FKL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1497:CLFO RS01075
gene id: 1497:CLFO_RS01075
uniprot id: A0A1D9FJT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1497:CLFO RS17955
gene id: 1497:CLFO_RS17955
uniprot id: A0A1D9FI72
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

1497:CLFO RS09990
gene id: 1497:CLFO_RS09990
uniprot id: A0A1D9FNZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1497:CLFO RS11730
gene id: 1497:CLFO_RS11730
uniprot id: A0A1D9FPX5
names: Subcellular Location Annotation
messages: Membrane

1497:CLFO RS09840
gene id: 1497:CLFO_RS09840
uniprot id: A0A1D9FNX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1497:CLFO RS18825
gene id: 1497:CLFO_RS18825
uniprot id: A0A1D9FHY4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1497:CLFO RS09330
gene id: 1497:CLFO_RS09330
uniprot id: A0A1D9FNP0
names: Similarity
messages: Belongs to the UPF0342 family.

1497:CLFO RS01890
gene id: 1497:CLFO_RS01890
uniprot id: A0A1D9FKA5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1497:CLFO RS02090
gene id: 1497:CLFO_RS02090
uniprot id: A0A1D9FK41
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1497:CLFO RS02150
gene id: 1497:CLFO_RS02150
uniprot id: A0A1D9FK75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1497:CLFO RS02375
gene id: 1497:CLFO_RS02375
uniprot id: A0A1D9FK84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1497:CLFO RS11465
gene id: 1497:CLFO_RS11465
uniprot id: A0A1D9FPT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1497:CLFO RS01770
gene id: 1497:CLFO_RS01770
uniprot id: A0A1D9FK10
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1497:CLFO RS19680
gene id: 1497:CLFO_RS19680
uniprot id: A0A1D9FI56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1497:CLFO RS03315
gene id: 1497:CLFO_RS03315
uniprot id: A0A1D9FKX0
names: Similarity
messages: Belongs to the UPF0749 family.

1497:CLFO RS10865
gene id: 1497:CLFO_RS10865
uniprot id: A0A1D9FPJ6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1497:CLFO RS17680
gene id: 1497:CLFO_RS17680
uniprot id: A0A1D9FHM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1497:CLFO RS21415
gene id: 1497:CLFO_RS21415
uniprot id: A0A1D9FJU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.