1486262:TM49 RS05415
gene id: 1486262:TM49_RS05415
uniprot id: A0A0D5LM27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS11725
gene id: 1486262:TM49_RS11725
uniprot id: A0A0D5LVU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS10990
gene id: 1486262:TM49_RS10990
uniprot id: A0A0D5LVZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1486262:TM49 RS14485
gene id: 1486262:TM49_RS14485
uniprot id: A0A0D5LTB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1486262:TM49 RS06995
gene id: 1486262:TM49_RS06995
uniprot id: A0A0D5LMS3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1486262:TM49 RS10090
gene id: 1486262:TM49_RS10090
uniprot id: A0A0D5LNZ0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1486262:TM49 RS02415
gene id: 1486262:TM49_RS02415
uniprot id: A0A0D5LKQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS00970
gene id: 1486262:TM49_RS00970
uniprot id: A0A0D5LK96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS12980
gene id: 1486262:TM49_RS12980
uniprot id: A0A0D5LRL1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1486262:TM49 RS04640
gene id: 1486262:TM49_RS04640
uniprot id: A0A0D5LLR5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS04730
gene id: 1486262:TM49_RS04730
uniprot id: A0A0D5LLX5
names: Similarity
messages: Belongs to the YkuD family.

1486262:TM49 RS00670
gene id: 1486262:TM49_RS00670
uniprot id: A0A0D5LMJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS22305
gene id: 1486262:TM49_RS22305
uniprot id: A0A0D5LU78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS12855
gene id: 1486262:TM49_RS12855
uniprot id: A0A0D5LWL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1486262:TM49 RS14925
gene id: 1486262:TM49_RS14925
uniprot id: A0A0D5LRC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1486262:TM49 RS09850
gene id: 1486262:TM49_RS09850
uniprot id: A0A0D5LNW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1486262:TM49 RS09720
gene id: 1486262:TM49_RS09720
uniprot id: A0A0D5LNU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1486262:TM49 RS11475
gene id: 1486262:TM49_RS11475
uniprot id: A0A0D5LQW8
names: Similarity
messages: Belongs to the GST superfamily.

1486262:TM49 RS02505
gene id: 1486262:TM49_RS02505
uniprot id: A0A0D5LKW7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1486262:TM49 RS05920
gene id: 1486262:TM49_RS05920
uniprot id: A0A0D5LME3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS08540
gene id: 1486262:TM49_RS08540
uniprot id: A0A0D5LP39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS09390
gene id: 1486262:TM49_RS09390
uniprot id: A0A0D5LNM1
names: Similarity
messages: Belongs to the Dps family.

1486262:TM49 RS14940
gene id: 1486262:TM49_RS14940
uniprot id: A0A0D5LTH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1486262:TM49 RS04740
gene id: 1486262:TM49_RS04740
uniprot id: A0A0D5LPA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS08610
gene id: 1486262:TM49_RS08610
uniprot id: A0A0D5LP50
names: Similarity
messages: Belongs to the asparagine synthetase family.

1486262:TM49 RS15100
gene id: 1486262:TM49_RS15100
uniprot id: A0A0D5LR52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1486262:TM49 RS12270
gene id: 1486262:TM49_RS12270
uniprot id: A0A0D5LQ50
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1486262:TM49 RS19635
gene id: 1486262:TM49_RS19635
uniprot id: A0A0D5LVI6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1486262:TM49 RS21820
gene id: 1486262:TM49_RS21820
uniprot id: A0A0D5LUG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS10225
gene id: 1486262:TM49_RS10225
uniprot id: A0A0D5LQC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1486262:TM49 RS21110
gene id: 1486262:TM49_RS21110
uniprot id: A0A0D5LUE8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1486262:TM49 RS10170
gene id: 1486262:TM49_RS10170
uniprot id: A0A0D5LQB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS10695
gene id: 1486262:TM49_RS10695
uniprot id: A0A0D5LP80
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1486262:TM49 RS01845
gene id: 1486262:TM49_RS01845
uniprot id: A0A0D5LUF0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS00855
gene id: 1486262:TM49_RS00855
uniprot id: A0A0D5LLB4
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS09690
gene id: 1486262:TM49_RS09690
uniprot id: A0A0D5LRD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS14360
gene id: 1486262:TM49_RS14360
uniprot id: A0A0D5LR44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1486262:TM49 RS09245
gene id: 1486262:TM49_RS09245
uniprot id: A0A0D5LPY2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1486262:TM49 RS10430
gene id: 1486262:TM49_RS10430
uniprot id: A0A0D5LPE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1486262:TM49 RS03610
gene id: 1486262:TM49_RS03610
uniprot id: A0A0D5LVW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS22210
gene id: 1486262:TM49_RS22210
uniprot id: A0A0D5LV01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS02525
gene id: 1486262:TM49_RS02525
uniprot id: A0A0D5LKS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS14435
gene id: 1486262:TM49_RS14435
uniprot id: A0A0D5LRN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1486262:TM49 RS22100
gene id: 1486262:TM49_RS22100
uniprot id: A0A0D5LVG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1486262:TM49 RS16365
gene id: 1486262:TM49_RS16365
uniprot id: A0A0D5LT19
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS06710
gene id: 1486262:TM49_RS06710
uniprot id: A0A0D5LMN7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS05425
gene id: 1486262:TM49_RS05425
uniprot id: A0A0D5LMS8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS18390
gene id: 1486262:TM49_RS18390
uniprot id: A0A0D5LT93
names: Similarity
messages: Belongs to the GST superfamily.

1486262:TM49 RS19450
gene id: 1486262:TM49_RS19450
uniprot id: A0A0D5LVD7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1486262:TM49 RS16295
gene id: 1486262:TM49_RS16295
uniprot id: A0A0D5LU64
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS13440
gene id: 1486262:TM49_RS13440
uniprot id: A0A0D5LRA5
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

1486262:TM49 RS13995
gene id: 1486262:TM49_RS13995
uniprot id: A0A0D5LRH4
names: Similarity
messages: Belongs to the sulfatase family.

1486262:TM49 RS09780
gene id: 1486262:TM49_RS09780
uniprot id: A0A0D5LQ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS12580
gene id: 1486262:TM49_RS12580
uniprot id: A0A0D5LQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS16700
gene id: 1486262:TM49_RS16700
uniprot id: A0A0D5LRZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1486262:TM49 RS16480
gene id: 1486262:TM49_RS16480
uniprot id: A0A0D5LT34
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1486262:TM49 RS21465
gene id: 1486262:TM49_RS21465
uniprot id: A0A0D5LW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS06695
gene id: 1486262:TM49_RS06695
uniprot id: A0A0D5LNW9
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS06440
gene id: 1486262:TM49_RS06440
uniprot id: A0A0D5LNS6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1486262:TM49 RS21885
gene id: 1486262:TM49_RS21885
uniprot id: A0A0D5LUH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS17175
gene id: 1486262:TM49_RS17175
uniprot id: A0A0D5LST7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1486262:TM49 RS02270
gene id: 1486262:TM49_RS02270
uniprot id: A0A0D5LKS6
names: Similarity
messages: Belongs to the GbsR family.

1486262:TM49 RS09015
gene id: 1486262:TM49_RS09015
uniprot id: A0A0D5LNI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS10175
gene id: 1486262:TM49_RS10175
uniprot id: A0A0D5LRJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS08435
gene id: 1486262:TM49_RS08435
uniprot id: A0A0D5LNA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1486262:TM49 RS12745
gene id: 1486262:TM49_RS12745
uniprot id: A0A0D5LSI8
names: Similarity
messages: Belongs to the pyruvate kinase family.

1486262:TM49 RS18005
gene id: 1486262:TM49_RS18005
uniprot id: A0A0D5LUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1486262:TM49 RS03535
gene id: 1486262:TM49_RS03535
uniprot id: A0A0D5LM09
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS09620
gene id: 1486262:TM49_RS09620
uniprot id: A0A0D5LQ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1486262:TM49 RS20790
gene id: 1486262:TM49_RS20790
uniprot id: A0A0D5LVZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS10930
gene id: 1486262:TM49_RS10930
uniprot id: A0A0D5LQN0
names: Subunit
messages: Homodimer.

1486262:TM49 RS00820
gene id: 1486262:TM49_RS00820
uniprot id: A0A0D5LLA7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1486262:TM49 RS12660
gene id: 1486262:TM49_RS12660
uniprot id: A0A0D5LQV6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M81 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC).

1486262:TM49 RS20130
gene id: 1486262:TM49_RS20130
uniprot id: A0A0D5LU15
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS07730
gene id: 1486262:TM49_RS07730
uniprot id: A0A0D5LP98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS09715
gene id: 1486262:TM49_RS09715
uniprot id: A0A0D5LRE0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1486262:TM49 RS17660
gene id: 1486262:TM49_RS17660
uniprot id: A0A0D5LSA5
names: Similarity
messages: Belongs to the SfsA family.

1486262:TM49 RS15520
gene id: 1486262:TM49_RS15520
uniprot id: A0A0D5LRJ6
names: Similarity
messages: Belongs to the NifZ family.

1486262:TM49 RS16565
gene id: 1486262:TM49_RS16565
uniprot id: A0A0D5LT48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1486262:TM49 RS05925
gene id: 1486262:TM49_RS05925
uniprot id: A0A0D5LNH8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS21770
gene id: 1486262:TM49_RS21770
uniprot id: A0A0D5LWB0
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

1486262:TM49 RS21875
gene id: 1486262:TM49_RS21875
uniprot id: A0A0D5LUS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS00430
gene id: 1486262:TM49_RS00430
uniprot id: A0A0D5LMF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS07725
gene id: 1486262:TM49_RS07725
uniprot id: A0A0D5LN79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS17980
gene id: 1486262:TM49_RS17980
uniprot id: A0A0D5LUU2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1486262:TM49 RS00575
gene id: 1486262:TM49_RS00575
uniprot id: A0A0D5LK03
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1486262:TM49 RS05165
gene id: 1486262:TM49_RS05165
uniprot id: A0A0D5LLY6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS13920
gene id: 1486262:TM49_RS13920
uniprot id: A0A0D5LRX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1486262:TM49 RS00630
gene id: 1486262:TM49_RS00630
uniprot id: A0A0D5LMI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1486262:TM49 RS06485
gene id: 1486262:TM49_RS06485
uniprot id: A0A0D5LMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1486262:TM49 RS03180
gene id: 1486262:TM49_RS03180
uniprot id: A0A0D5LL96
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1486262:TM49 RS12925
gene id: 1486262:TM49_RS12925
uniprot id: A0A0D5LVY4
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1486262:TM49 RS00890
gene id: 1486262:TM49_RS00890
uniprot id: A0A0D5LK88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1486262:TM49 RS16000
gene id: 1486262:TM49_RS16000
uniprot id: A0A0D5LSS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1486262:TM49 RS09805
gene id: 1486262:TM49_RS09805
uniprot id: A0A0D5LP58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1486262:TM49 RS16005
gene id: 1486262:TM49_RS16005
uniprot id: A0A0D5LTY5
names: Similarity
messages: Belongs to the GcvT family.

1486262:TM49 RS07950
gene id: 1486262:TM49_RS07950
uniprot id: A0A0D5LN27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1486262:TM49 RS09205
gene id: 1486262:TM49_RS09205
uniprot id: A0A0D5LNK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

1486262:TM49 RS03065
gene id: 1486262:TM49_RS03065
uniprot id: A0A0D5LMB7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS06095
gene id: 1486262:TM49_RS06095
uniprot id: A0A0D5LN63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS08230
gene id: 1486262:TM49_RS08230
uniprot id: A0A0D5LNF9
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS03645
gene id: 1486262:TM49_RS03645
uniprot id: A0A0D5LM20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1486262:TM49 RS16965
gene id: 1486262:TM49_RS16965
uniprot id: A0A0D5LUG1
names: Similarity
messages: Belongs to the YkuD family.

1486262:TM49 RS11900
gene id: 1486262:TM49_RS11900
uniprot id: A0A0D5LQJ5
names: Similarity
messages: Belongs to the YkuD family.

1486262:TM49 RS02255
gene id: 1486262:TM49_RS02255
uniprot id: A0A0D5LN77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1486262:TM49 RS21340
gene id: 1486262:TM49_RS21340
uniprot id: A0A0D5LWP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1486262:TM49 RS20390
gene id: 1486262:TM49_RS20390
uniprot id: A0A0D5LWM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1486262:TM49 RS00090
gene id: 1486262:TM49_RS00090
uniprot id: A0A0D5LL01
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS17645
gene id: 1486262:TM49_RS17645
uniprot id: A0A0D5LSL6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1486262:TM49 RS03990
gene id: 1486262:TM49_RS03990
uniprot id: A0A0D5LLH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS02280
gene id: 1486262:TM49_RS02280
uniprot id: A0A0D5LLX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1486262:TM49 RS18070
gene id: 1486262:TM49_RS18070
uniprot id: A0A0D5LUV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1486262:TM49 RS21985
gene id: 1486262:TM49_RS21985
uniprot id: A0A0D5LUX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS01125
gene id: 1486262:TM49_RS01125
uniprot id: A0A0D5LKW3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1486262:TM49 RS07210
gene id: 1486262:TM49_RS07210
uniprot id: A0A0D5LQB7
names: Similarity
messages: Belongs to the carbamate kinase family.

1486262:TM49 RS20720
gene id: 1486262:TM49_RS20720
uniprot id: A0A0D5LU13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1486262:TM49 RS08925
gene id: 1486262:TM49_RS08925
uniprot id: A0A0D5LNQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS00505
gene id: 1486262:TM49_RS00505
uniprot id: A0A0D5LMH0
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS15140
gene id: 1486262:TM49_RS15140
uniprot id: A0A0D5LR57
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1486262:TM49 RS20905
gene id: 1486262:TM49_RS20905
uniprot id: A0A0D5LUC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1486262:TM49 RS12210
gene id: 1486262:TM49_RS12210
uniprot id: A0A0D5LSB4
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS17565
gene id: 1486262:TM49_RS17565
uniprot id: A0A0D5LSK7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1486262:TM49 RS14970
gene id: 1486262:TM49_RS14970
uniprot id: A0A0D5LTH8
names: Similarity
messages: Belongs to the citrate synthase family.

1486262:TM49 RS13245
gene id: 1486262:TM49_RS13245
uniprot id: A0A0D5LSU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS00155
gene id: 1486262:TM49_RS00155
uniprot id: A0A0D5LJT5
names: Subcellular Location Annotation
messages: Cytoplasm

1486262:TM49 RS06565
gene id: 1486262:TM49_RS06565
uniprot id: A0A0D5LND3
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1486262:TM49 RS01755
gene id: 1486262:TM49_RS01755
uniprot id: A0A0D5LWS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS08790
gene id: 1486262:TM49_RS08790
uniprot id: A0A0D5LPR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1486262:TM49 RS20635
gene id: 1486262:TM49_RS20635
uniprot id: A0A0D5LTK5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alphaproteobacteria porin family.
messages: Cell outer membrane
messages: Consists of 16-stranded beta-barrel sheets, with large surface-exposed loops, that form a transmembrane pore at the center of each barrel. The pore is partially ocluded by a peptide loop that folds into the pore lumen.
messages: Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.

1486262:TM49 RS19445
gene id: 1486262:TM49_RS19445
uniprot id: A0A0D5LUA2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1486262:TM49 RS09925
gene id: 1486262:TM49_RS09925
uniprot id: A0A0D5LP74
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1486262:TM49 RS19060
gene id: 1486262:TM49_RS19060
uniprot id: A0A0D5LPN4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1486262:TM49 RS01725
gene id: 1486262:TM49_RS01725
uniprot id: A0A0D5LL43
names: Similarity
messages: Belongs to the UPF0335 family.

1486262:TM49 RS18250
gene id: 1486262:TM49_RS18250
uniprot id: A0A0D5LSV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1486262:TM49 RS15930
gene id: 1486262:TM49_RS15930
uniprot id: A0A0D5LS84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS06040
gene id: 1486262:TM49_RS06040
uniprot id: A0A0D5LMJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS19210
gene id: 1486262:TM49_RS19210
uniprot id: A0A0D5LV96
names: Similarity
messages: Belongs to the peptidase S8 family.

1486262:TM49 RS18700
gene id: 1486262:TM49_RS18700
uniprot id: A0A0D5LY01
names: Similarity
messages: Belongs to the ros/MucR family.

1486262:TM49 RS13005
gene id: 1486262:TM49_RS13005
uniprot id: A0A0D5LQJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1486262:TM49 RS11130
gene id: 1486262:TM49_RS11130
uniprot id: A0A0D5LPP9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1486262:TM49 RS05995
gene id: 1486262:TM49_RS05995
uniprot id: A0A0D5LPT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1486262:TM49 RS22320
gene id: 1486262:TM49_RS22320
uniprot id: A0A0D5LUP7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS18485
gene id: 1486262:TM49_RS18485
uniprot id: A0A0D5LSM9
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1486262:TM49 RS17020
gene id: 1486262:TM49_RS17020
uniprot id: A0A0D5LSS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS21485
gene id: 1486262:TM49_RS21485
uniprot id: A0A0D5LV75
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS13925
gene id: 1486262:TM49_RS13925
uniprot id: A0A0D5LT35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS19440
gene id: 1486262:TM49_RS19440
uniprot id: A0A0D5LTC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1486262:TM49 RS21090
gene id: 1486262:TM49_RS21090
uniprot id: A0A0D5LV08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1486262:TM49 RS11765
gene id: 1486262:TM49_RS11765
uniprot id: A0A0D5LPY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1486262:TM49 RS18235
gene id: 1486262:TM49_RS18235
uniprot id: A0A0D5LUX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1486262:TM49 RS20355
gene id: 1486262:TM49_RS20355
uniprot id: A0A0D5LTV3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1486262:TM49 RS19880
gene id: 1486262:TM49_RS19880
uniprot id: A0A0D5LTX9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1486262:TM49 RS06635
gene id: 1486262:TM49_RS06635
uniprot id: A0A0D5LNW0
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

1486262:TM49 RS09165
gene id: 1486262:TM49_RS09165
uniprot id: A0A0D5LNJ7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1486262:TM49 RS08130
gene id: 1486262:TM49_RS08130
uniprot id: A0A0D5LPF9
names: Similarity
messages: Belongs to the universal stress protein A family.

1486262:TM49 RS05345
gene id: 1486262:TM49_RS05345
uniprot id: A0A0D5LN95
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS21525
gene id: 1486262:TM49_RS21525
uniprot id: A0A0D5LTX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1486262:TM49 RS06630
gene id: 1486262:TM49_RS06630
uniprot id: A0A0D5LMT9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS16665
gene id: 1486262:TM49_RS16665
uniprot id: A0A0D5LRZ2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1486262:TM49 RS11830
gene id: 1486262:TM49_RS11830
uniprot id: A0A0D5LR17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1486262:TM49 RS02360
gene id: 1486262:TM49_RS02360
uniprot id: A0A0D5LKQ0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1486262:TM49 RS05020
gene id: 1486262:TM49_RS05020
uniprot id: A0A0D5LMK8
names: Similarity
messages: Belongs to the TrpF family.

1486262:TM49 RS09880
gene id: 1486262:TM49_RS09880
uniprot id: A0A0D5LPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS13240
gene id: 1486262:TM49_RS13240
uniprot id: A0A0D5LRP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS14695
gene id: 1486262:TM49_RS14695
uniprot id: A0A0D5LQZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1486262:TM49 RS14665
gene id: 1486262:TM49_RS14665
uniprot id: A0A0D5LS87
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1486262:TM49 RS19935
gene id: 1486262:TM49_RS19935
uniprot id: A0A0D5LTY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1486262:TM49 RS06210
gene id: 1486262:TM49_RS06210
uniprot id: A0A0D5LMG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1486262:TM49 RS01355
gene id: 1486262:TM49_RS01355
uniprot id: A0A0D5LKF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS14420
gene id: 1486262:TM49_RS14420
uniprot id: A0A0D5LS43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1486262:TM49 RS17665
gene id: 1486262:TM49_RS17665
uniprot id: A0A0D5LSY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1486262:TM49 RS21835
gene id: 1486262:TM49_RS21835
uniprot id: A0A0D5LU14
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1486262:TM49 RS06480
gene id: 1486262:TM49_RS06480
uniprot id: A0A0D5LNB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1486262:TM49 RS08185
gene id: 1486262:TM49_RS08185
uniprot id: A0A0D5LPH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS07475
gene id: 1486262:TM49_RS07475
uniprot id: A0A0D5LNP2
names: Similarity
messages: Belongs to the UPF0047 family.

1486262:TM49 RS20260
gene id: 1486262:TM49_RS20260
uniprot id: A0A0D5LTF6
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

1486262:TM49 RS04735
gene id: 1486262:TM49_RS04735
uniprot id: A0A0D5LN09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS05845
gene id: 1486262:TM49_RS05845
uniprot id: A0A0D5LMD1
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1486262:TM49 RS18730
gene id: 1486262:TM49_RS18730
uniprot id: A0A0D5LSR7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1486262:TM49 RS14280
gene id: 1486262:TM49_RS14280
uniprot id: A0A0D5LRK8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1486262:TM49 RS00265
gene id: 1486262:TM49_RS00265
uniprot id: A0A0D5LJV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS05360
gene id: 1486262:TM49_RS05360
uniprot id: A0A0D5LMR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS20520
gene id: 1486262:TM49_RS20520
uniprot id: A0A0D5LTY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

1486262:TM49 RS15440
gene id: 1486262:TM49_RS15440
uniprot id: A0A0D5LS04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1486262:TM49 RS03515
gene id: 1486262:TM49_RS03515
uniprot id: A0A0D5LLE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS15045
gene id: 1486262:TM49_RS15045
uniprot id: A0A0D5LRV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS01310
gene id: 1486262:TM49_RS01310
uniprot id: A0A0D5LLI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS05200
gene id: 1486262:TM49_RS05200
uniprot id: A0A0D5LMN6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1486262:TM49 RS05115
gene id: 1486262:TM49_RS05115
uniprot id: A0A0D5LPF8
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS13980
gene id: 1486262:TM49_RS13980
uniprot id: A0A0D5LW08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS16695
gene id: 1486262:TM49_RS16695
uniprot id: A0A0D5LXV3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1486262:TM49 RS16570
gene id: 1486262:TM49_RS16570
uniprot id: A0A0D5LUB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1486262:TM49 RS16160
gene id: 1486262:TM49_RS16160
uniprot id: A0A0D5LVF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1486262:TM49 RS19840
gene id: 1486262:TM49_RS19840
uniprot id: A0A0D5LVL7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1486262:TM49 RS10795
gene id: 1486262:TM49_RS10795
uniprot id: A0A0D5LRS3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1486262:TM49 RS03450
gene id: 1486262:TM49_RS03450
uniprot id: A0A0D5LLD3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1486262:TM49 RS18870
gene id: 1486262:TM49_RS18870
uniprot id: A0A0D5LU20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1486262:TM49 RS15585
gene id: 1486262:TM49_RS15585
uniprot id: A0A0D5LS23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1486262:TM49 RS03400
gene id: 1486262:TM49_RS03400
uniprot id: A0A0D5LNS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS18165
gene id: 1486262:TM49_RS18165
uniprot id: A0A0D5LWY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1486262:TM49 RS05515
gene id: 1486262:TM49_RS05515
uniprot id: A0A0D5LM40
names: Similarity
messages: Belongs to the CFA/CMAS family.

1486262:TM49 RS01790
gene id: 1486262:TM49_RS01790
uniprot id: A0A0D5LKH4
names: Function
names: Subcellular Location Annotation
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS18715
gene id: 1486262:TM49_RS18715
uniprot id: A0A0D5LT25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS17695
gene id: 1486262:TM49_RS17695
uniprot id: A0A0D5LSB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS05750
gene id: 1486262:TM49_RS05750
uniprot id: A0A0D5LPQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS08355
gene id: 1486262:TM49_RS08355
uniprot id: A0A0D5LP08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS07485
gene id: 1486262:TM49_RS07485
uniprot id: A0A0D5LP72
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1486262:TM49 RS08175
gene id: 1486262:TM49_RS08175
uniprot id: A0A0D5LNY1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1486262:TM49 RS08940
gene id: 1486262:TM49_RS08940
uniprot id: A0A0D5LR13
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1486262:TM49 RS06265
gene id: 1486262:TM49_RS06265
uniprot id: A0A0D5LMN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS03485
gene id: 1486262:TM49_RS03485
uniprot id: A0A0D5LMH1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1486262:TM49 RS10830
gene id: 1486262:TM49_RS10830
uniprot id: A0A0D5LPA7
names: Similarity
messages: Belongs to the UPF0303 family.

1486262:TM49 RS17900
gene id: 1486262:TM49_RS17900
uniprot id: A0A0D5LTN2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1486262:TM49 RS07940
gene id: 1486262:TM49_RS07940
uniprot id: A0A0D5LPD0
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

1486262:TM49 RS02405
gene id: 1486262:TM49_RS02405
uniprot id: A0A0D5LLZ3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1486262:TM49 RS20235
gene id: 1486262:TM49_RS20235
uniprot id: A0A0D5LUQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS01110
gene id: 1486262:TM49_RS01110
uniprot id: A0A0D5LLE9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

1486262:TM49 RS00415
gene id: 1486262:TM49_RS00415
uniprot id: A0A0D5LKM2
names: Similarity
messages: Belongs to the peptidase S41A family.

1486262:TM49 RS09885
gene id: 1486262:TM49_RS09885
uniprot id: A0A0D5LVQ4
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1486262:TM49 RS19125
gene id: 1486262:TM49_RS19125
uniprot id: A0A0D5LT78
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1486262:TM49 RS20045
gene id: 1486262:TM49_RS20045
uniprot id: A0A0D5LTD5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1486262:TM49 RS07205
gene id: 1486262:TM49_RS07205
uniprot id: A0A0D5LP32
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS21190
gene id: 1486262:TM49_RS21190
uniprot id: A0A0D5LTS7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1486262:TM49 RS15870
gene id: 1486262:TM49_RS15870
uniprot id: A0A0D5LS73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS22235
gene id: 1486262:TM49_RS22235
uniprot id: A0A0D5LU71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1486262:TM49 RS05755
gene id: 1486262:TM49_RS05755
uniprot id: A0A0D5LM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS11455
gene id: 1486262:TM49_RS11455
uniprot id: A0A0D5LPJ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS02345
gene id: 1486262:TM49_RS02345
uniprot id: A0A0D5LKT6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1486262:TM49 RS03030
gene id: 1486262:TM49_RS03030
uniprot id: A0A0D5LVU9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1486262:TM49 RS01300
gene id: 1486262:TM49_RS01300
uniprot id: A0A0D5LKY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS00885
gene id: 1486262:TM49_RS00885
uniprot id: A0A0D5LWN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1486262:TM49 RS14165
gene id: 1486262:TM49_RS14165
uniprot id: A0A0D5LQR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1486262:TM49 RS08720
gene id: 1486262:TM49_RS08720
uniprot id: A0A0D5LP70
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1486262:TM49 RS15590
gene id: 1486262:TM49_RS15590
uniprot id: A0A0D5LVE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1486262:TM49 RS16680
gene id: 1486262:TM49_RS16680
uniprot id: A0A0D5LT70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1486262:TM49 RS03675
gene id: 1486262:TM49_RS03675
uniprot id: A0A0D5LM24
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1486262:TM49 RS19295
gene id: 1486262:TM49_RS19295
uniprot id: A0A0D5LU81
names: Subcellular Location Annotation
messages: Cell inner membrane

1486262:TM49 RS06745
gene id: 1486262:TM49_RS06745
uniprot id: A0A0D5LQ59
names: Function
names: Similarity
messages: Belongs to the amidase family.
messages: Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).

1486262:TM49 RS00470
gene id: 1486262:TM49_RS00470
uniprot id: A0A0D5LK38
names: Similarity
messages: Belongs to the Gfa family.

1486262:TM49 RS05835
gene id: 1486262:TM49_RS05835
uniprot id: A0A0D5LM79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1486262:TM49 RS17010
gene id: 1486262:TM49_RS17010
uniprot id: A0A0D5LVG7
names: Caution
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS00725
gene id: 1486262:TM49_RS00725
uniprot id: A0A0D5LL97
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1486262:TM49 RS08580
gene id: 1486262:TM49_RS08580
uniprot id: A0A0D5LPN0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1486262:TM49 RS08010
gene id: 1486262:TM49_RS08010
uniprot id: A0A0D5LN34
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1486262:TM49 RS21060
gene id: 1486262:TM49_RS21060
uniprot id: A0A0D5LV04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1486262:TM49 RS14350
gene id: 1486262:TM49_RS14350
uniprot id: A0A0D5LRL8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1486262:TM49 RS14635
gene id: 1486262:TM49_RS14635
uniprot id: A0A0D5LW26
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1486262:TM49 RS18800
gene id: 1486262:TM49_RS18800
uniprot id: A0A0D5LTF1
names: Similarity
messages: Belongs to the UPF0173 family.

1486262:TM49 RS13460
gene id: 1486262:TM49_RS13460
uniprot id: A0A0D5LQH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1486262:TM49 RS19490
gene id: 1486262:TM49_RS19490
uniprot id: A0A0D5LTS0
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

1486262:TM49 RS15855
gene id: 1486262:TM49_RS15855
uniprot id: A0A0D5LTV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS14200
gene id: 1486262:TM49_RS14200
uniprot id: A0A0D5LR19
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1486262:TM49 RS09665
gene id: 1486262:TM49_RS09665
uniprot id: A0A0D5LNT3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1486262:TM49 RS15470
gene id: 1486262:TM49_RS15470
uniprot id: A0A0D5LS08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1486262:TM49 RS02015
gene id: 1486262:TM49_RS02015
uniprot id: A0A0D5LUF9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1486262:TM49 RS10940
gene id: 1486262:TM49_RS10940
uniprot id: A0A0D5LPC5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1486262:TM49 RS02545
gene id: 1486262:TM49_RS02545
uniprot id: A0A0D5LNC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1486262:TM49 RS19435
gene id: 1486262:TM49_RS19435
uniprot id: A0A0D5LTN8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1486262:TM49 RS01225
gene id: 1486262:TM49_RS01225
uniprot id: A0A0D5LK90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1486262:TM49 RS05085
gene id: 1486262:TM49_RS05085
uniprot id: A0A0D5LPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1486262:TM49 RS00865
gene id: 1486262:TM49_RS00865
uniprot id: A0A0D5LVN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS11120
gene id: 1486262:TM49_RS11120
uniprot id: A0A0D5LPF4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1486262:TM49 RS10935
gene id: 1486262:TM49_RS10935
uniprot id: A0A0D5LRT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1486262:TM49 RS13000
gene id: 1486262:TM49_RS13000
uniprot id: A0A0D5LR40
names: Similarity
messages: Belongs to the Gfa family.

1486262:TM49 RS00965
gene id: 1486262:TM49_RS00965
uniprot id: A0A0D5LKT9
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1486262:TM49 RS04090
gene id: 1486262:TM49_RS04090
uniprot id: A0A0D5LLM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS14580
gene id: 1486262:TM49_RS14580
uniprot id: A0A0D5LS71
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1486262:TM49 RS01400
gene id: 1486262:TM49_RS01400
uniprot id: A0A0D5LLK0
names: Similarity
messages: Belongs to the glutamate synthase family.

1486262:TM49 RS11405
gene id: 1486262:TM49_RS11405
uniprot id: A0A0D5LWH0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS02470
gene id: 1486262:TM49_RS02470
uniprot id: A0A0D5LKR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS12235
gene id: 1486262:TM49_RS12235
uniprot id: A0A0D5LQ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS00995
gene id: 1486262:TM49_RS00995
uniprot id: A0A0D5LUW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS01290
gene id: 1486262:TM49_RS01290
uniprot id: A0A0D5LMT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS20320
gene id: 1486262:TM49_RS20320
uniprot id: A0A0D5LU39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1486262:TM49 RS14560
gene id: 1486262:TM49_RS14560
uniprot id: A0A0D5LQX5
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS20430
gene id: 1486262:TM49_RS20430
uniprot id: A0A0D5LVU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1486262:TM49 RS08880
gene id: 1486262:TM49_RS08880
uniprot id: A0A0D5LR05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS02135
gene id: 1486262:TM49_RS02135
uniprot id: A0A0D5LKQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1486262:TM49 RS08495
gene id: 1486262:TM49_RS08495
uniprot id: A0A0D5LNB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1486262:TM49 RS01000
gene id: 1486262:TM49_RS01000
uniprot id: A0A0D5LKU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS10095
gene id: 1486262:TM49_RS10095
uniprot id: A0A0D5LPU3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1486262:TM49 RS22290
gene id: 1486262:TM49_RS22290
uniprot id: A0A0D5LUP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS14660
gene id: 1486262:TM49_RS14660
uniprot id: A0A0D5LR88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1486262:TM49 RS13290
gene id: 1486262:TM49_RS13290
uniprot id: A0A0D5LSU9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS13765
gene id: 1486262:TM49_RS13765
uniprot id: A0A0D5LRF1
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

1486262:TM49 RS13185
gene id: 1486262:TM49_RS13185
uniprot id: A0A0D5LST9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1486262:TM49 RS19475
gene id: 1486262:TM49_RS19475
uniprot id: A0A0D5LVG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

1486262:TM49 RS01830
gene id: 1486262:TM49_RS01830
uniprot id: A0A0D5LL58
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1486262:TM49 RS08990
gene id: 1486262:TM49_RS08990
uniprot id: A0A0D5LPC1
names: Similarity
messages: Belongs to the UxaA family.

1486262:TM49 RS19990
gene id: 1486262:TM49_RS19990
uniprot id: A0A0D5LTP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1486262:TM49 RS06600
gene id: 1486262:TM49_RS06600
uniprot id: A0A0D5LX40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS07705
gene id: 1486262:TM49_RS07705
uniprot id: A0A0D5LMZ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1486262:TM49 RS01020
gene id: 1486262:TM49_RS01020
uniprot id: A0A0D5LVN7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1486262:TM49 RS04450
gene id: 1486262:TM49_RS04450
uniprot id: A0A0D5LLS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1486262:TM49 RS06815
gene id: 1486262:TM49_RS06815
uniprot id: A0A0D5LNY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS06780
gene id: 1486262:TM49_RS06780
uniprot id: A0A0D5LQ63
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS20670
gene id: 1486262:TM49_RS20670
uniprot id: A0A0D5LU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS08475
gene id: 1486262:TM49_RS08475
uniprot id: A0A0D5LP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS15425
gene id: 1486262:TM49_RS15425
uniprot id: A0A0D5LTP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1486262:TM49 RS03820
gene id: 1486262:TM49_RS03820
uniprot id: A0A0D5LNX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS10770
gene id: 1486262:TM49_RS10770
uniprot id: A0A0D5LRR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS00130
gene id: 1486262:TM49_RS00130
uniprot id: A0A0D5LKI0
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS08405
gene id: 1486262:TM49_RS08405
uniprot id: A0A0D5LN97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1486262:TM49 RS11980
gene id: 1486262:TM49_RS11980
uniprot id: A0A0D5LQ18
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS00375
gene id: 1486262:TM49_RS00375
uniprot id: A0A0D5LME9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1486262:TM49 RS11365
gene id: 1486262:TM49_RS11365
uniprot id: A0A0D5LW05
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS03800
gene id: 1486262:TM49_RS03800
uniprot id: A0A0D5LLI9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS20135
gene id: 1486262:TM49_RS20135
uniprot id: A0A0D5LTR7
names: Similarity
messages: Belongs to the peptidase S11 family.

1486262:TM49 RS08365
gene id: 1486262:TM49_RS08365
uniprot id: A0A0D5LNH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1486262:TM49 RS01220
gene id: 1486262:TM49_RS01220
uniprot id: A0A0D5LMS1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1486262:TM49 RS04815
gene id: 1486262:TM49_RS04815
uniprot id: A0A0D5LLU0
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS13425
gene id: 1486262:TM49_RS13425
uniprot id: A0A0D5LRR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1486262:TM49 RS16770
gene id: 1486262:TM49_RS16770
uniprot id: A0A0D5LSP1
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1486262:TM49 RS08810
gene id: 1486262:TM49_RS08810
uniprot id: A0A0D5LNN9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS19470
gene id: 1486262:TM49_RS19470
uniprot id: A0A0D5LUD1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS02555
gene id: 1486262:TM49_RS02555
uniprot id: A0A0D5LLH6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1486262:TM49 RS06220
gene id: 1486262:TM49_RS06220
uniprot id: A0A0D5LMM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1486262:TM49 RS19545
gene id: 1486262:TM49_RS19545
uniprot id: A0A0D5LTH4
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1486262:TM49 RS03115
gene id: 1486262:TM49_RS03115
uniprot id: A0A0D5LL86
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS03040
gene id: 1486262:TM49_RS03040
uniprot id: A0A0D5LWV5
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS20780
gene id: 1486262:TM49_RS20780
uniprot id: A0A0D5LU23
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS13265
gene id: 1486262:TM49_RS13265
uniprot id: A0A0D5LR80
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1486262:TM49 RS12605
gene id: 1486262:TM49_RS12605
uniprot id: A0A0D5LRC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS14525
gene id: 1486262:TM49_RS14525
uniprot id: A0A0D5LTC0
names: Similarity
messages: Belongs to the Gfa family.

1486262:TM49 RS21175
gene id: 1486262:TM49_RS21175
uniprot id: A0A0D5LV20
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1486262:TM49 RS06230
gene id: 1486262:TM49_RS06230
uniprot id: A0A0D5LNQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1486262:TM49 RS03480
gene id: 1486262:TM49_RS03480
uniprot id: A0A0D5LLD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS14430
gene id: 1486262:TM49_RS14430
uniprot id: A0A0D5LQV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1486262:TM49 RS05760
gene id: 1486262:TM49_RS05760
uniprot id: A0A0D5LW27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS14640
gene id: 1486262:TM49_RS14640
uniprot id: A0A0D5LS82
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1486262:TM49 RS07360
gene id: 1486262:TM49_RS07360
uniprot id: A0A0D5LMW3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1486262:TM49 RS00050
gene id: 1486262:TM49_RS00050
uniprot id: A0A0D5LKG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS03815
gene id: 1486262:TM49_RS03815
uniprot id: A0A0D5LWX8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS17295
gene id: 1486262:TM49_RS17295
uniprot id: A0A0D5LUK5
names: Similarity
messages: Belongs to the peptidase C40 family.

1486262:TM49 RS14265
gene id: 1486262:TM49_RS14265
uniprot id: A0A0D5LT81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS14590
gene id: 1486262:TM49_RS14590
uniprot id: A0A0D5LQX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1486262:TM49 RS19755
gene id: 1486262:TM49_RS19755
uniprot id: A0A0D5LT89
names: Similarity
messages: Belongs to the YciI family.

1486262:TM49 RS01030
gene id: 1486262:TM49_RS01030
uniprot id: A0A0D5LK61
names: Similarity
messages: Belongs to the YciI family.

1486262:TM49 RS05305
gene id: 1486262:TM49_RS05305
uniprot id: A0A0D5LM10
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1486262:TM49 RS16450
gene id: 1486262:TM49_RS16450
uniprot id: A0A0D5LWU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS14175
gene id: 1486262:TM49_RS14175
uniprot id: A0A0D5LR14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1486262:TM49 RS08080
gene id: 1486262:TM49_RS08080
uniprot id: A0A0D5LNW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1486262:TM49 RS21240
gene id: 1486262:TM49_RS21240
uniprot id: A0A0D5LV31
names: Similarity
messages: Belongs to the PRORSD1 family.

1486262:TM49 RS16375
gene id: 1486262:TM49_RS16375
uniprot id: A0A0D5LRV2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1486262:TM49 RS21585
gene id: 1486262:TM49_RS21585
uniprot id: A0A0D5LY98
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS05055
gene id: 1486262:TM49_RS05055
uniprot id: A0A0D5LLX2
names: Similarity
messages: Belongs to the thioredoxin family.

1486262:TM49 RS04225
gene id: 1486262:TM49_RS04225
uniprot id: A0A0D5LP35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS11750
gene id: 1486262:TM49_RS11750
uniprot id: A0A0D5LS52
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1486262:TM49 RS15290
gene id: 1486262:TM49_RS15290
uniprot id: A0A0D5LSH4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS17650
gene id: 1486262:TM49_RS17650
uniprot id: A0A0D5LTJ1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1486262:TM49 RS03555
gene id: 1486262:TM49_RS03555
uniprot id: A0A0D5LNU3
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS21225
gene id: 1486262:TM49_RS21225
uniprot id: A0A0D5LUG8
names: Similarity
messages: Belongs to the UPF0434 family.

1486262:TM49 RS21880
gene id: 1486262:TM49_RS21880
uniprot id: A0A0D5LWX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS19180
gene id: 1486262:TM49_RS19180
uniprot id: A0A0D5LSX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS16600
gene id: 1486262:TM49_RS16600
uniprot id: A0A0D5LUB7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1486262:TM49 RS05885
gene id: 1486262:TM49_RS05885
uniprot id: A0A0D5LNH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1486262:TM49 RS20025
gene id: 1486262:TM49_RS20025
uniprot id: A0A0D5LTQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1486262:TM49 RS09215
gene id: 1486262:TM49_RS09215
uniprot id: A0A0D5LNV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1486262:TM49 RS08190
gene id: 1486262:TM49_RS08190
uniprot id: A0A0D5LQP3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS12220
gene id: 1486262:TM49_RS12220
uniprot id: A0A0D5LQN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS07890
gene id: 1486262:TM49_RS07890
uniprot id: A0A0D5LQJ3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1486262:TM49 RS01065
gene id: 1486262:TM49_RS01065
uniprot id: A0A0D5LK65
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS12540
gene id: 1486262:TM49_RS12540
uniprot id: A0A0D5LQ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS17000
gene id: 1486262:TM49_RS17000
uniprot id: A0A0D5LTB5
names: Similarity
messages: Belongs to the UPF0178 family.

1486262:TM49 RS05245
gene id: 1486262:TM49_RS05245
uniprot id: A0A0D5LN75
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

1486262:TM49 RS06275
gene id: 1486262:TM49_RS06275
uniprot id: A0A0D5LQ03
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1486262:TM49 RS04515
gene id: 1486262:TM49_RS04515
uniprot id: A0A0D5LP78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS08630
gene id: 1486262:TM49_RS08630
uniprot id: A0A0D5LQW7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1486262:TM49 RS17605
gene id: 1486262:TM49_RS17605
uniprot id: A0A0D5LSL2
names: Similarity
messages: Belongs to the YkuD family.

1486262:TM49 RS08845
gene id: 1486262:TM49_RS08845
uniprot id: A0A0D5LVL9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1486262:TM49 RS09335
gene id: 1486262:TM49_RS09335
uniprot id: A0A0D5LPZ2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1486262:TM49 RS16710
gene id: 1486262:TM49_RS16710
uniprot id: A0A0D5LSN2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1486262:TM49 RS06545
gene id: 1486262:TM49_RS06545
uniprot id: A0A0D5LMS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1486262:TM49 RS02315
gene id: 1486262:TM49_RS02315
uniprot id: A0A0D5LKP6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1486262:TM49 RS10400
gene id: 1486262:TM49_RS10400
uniprot id: A0A0D5LQF3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1486262:TM49 RS07425
gene id: 1486262:TM49_RS07425
uniprot id: A0A0D5LMX1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS05645
gene id: 1486262:TM49_RS05645
uniprot id: A0A0D5LNE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1486262:TM49 RS20475
gene id: 1486262:TM49_RS20475
uniprot id: A0A0D5LTI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS11030
gene id: 1486262:TM49_RS11030
uniprot id: A0A0D5LRU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1486262:TM49 RS21715
gene id: 1486262:TM49_RS21715
uniprot id: A0A0D5LXB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1486262:TM49 RS20265
gene id: 1486262:TM49_RS20265
uniprot id: A0A0D5LU31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

1486262:TM49 RS01130
gene id: 1486262:TM49_RS01130
uniprot id: A0A0D5LKB9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1486262:TM49 RS03900
gene id: 1486262:TM49_RS03900
uniprot id: A0A0D5LLK2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS04145
gene id: 1486262:TM49_RS04145
uniprot id: A0A0D5LM84
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS16370
gene id: 1486262:TM49_RS16370
uniprot id: A0A0D5LU80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1486262:TM49 RS05045
gene id: 1486262:TM49_RS05045
uniprot id: A0A0D5LVA8
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1486262:TM49 RS18200
gene id: 1486262:TM49_RS18200
uniprot id: A0A0D5LUW9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1486262:TM49 RS04205
gene id: 1486262:TM49_RS04205
uniprot id: A0A0D5LLK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1486262:TM49 RS18660
gene id: 1486262:TM49_RS18660
uniprot id: A0A0D5LV36
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS06580
gene id: 1486262:TM49_RS06580
uniprot id: A0A0D5LNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS04715
gene id: 1486262:TM49_RS04715
uniprot id: A0A0D5LPA5
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS06525
gene id: 1486262:TM49_RS06525
uniprot id: A0A0D5LNU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS10530
gene id: 1486262:TM49_RS10530
uniprot id: A0A0D5LWF9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1486262:TM49 RS12450
gene id: 1486262:TM49_RS12450
uniprot id: A0A0D5LPZ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1486262:TM49 RS20870
gene id: 1486262:TM49_RS20870
uniprot id: A0A0D5LY86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1486262:TM49 RS20925
gene id: 1486262:TM49_RS20925
uniprot id: A0A0D5LTP4
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1486262:TM49 RS00205
gene id: 1486262:TM49_RS00205
uniprot id: A0A0D5LMC9
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1486262:TM49 RS05025
gene id: 1486262:TM49_RS05025
uniprot id: A0A0D5LVG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1486262:TM49 RS00070
gene id: 1486262:TM49_RS00070
uniprot id: A0A0D5LV29
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1486262:TM49 RS02800
gene id: 1486262:TM49_RS02800
uniprot id: A0A0D5LL10
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1486262:TM49 RS10140
gene id: 1486262:TM49_RS10140
uniprot id: A0A0D5LQB3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1486262:TM49 RS06490
gene id: 1486262:TM49_RS06490
uniprot id: A0A0D5LNT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS08670
gene id: 1486262:TM49_RS08670
uniprot id: A0A0D5LP60
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1486262:TM49 RS02695
gene id: 1486262:TM49_RS02695
uniprot id: A0A0D5LKV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1486262:TM49 RS18785
gene id: 1486262:TM49_RS18785
uniprot id: A0A0D5LWK3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.
messages: Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).

1486262:TM49 RS00835
gene id: 1486262:TM49_RS00835
uniprot id: A0A0D5LKS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1486262:TM49 RS21580
gene id: 1486262:TM49_RS21580
uniprot id: A0A0D5LW91
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1486262:TM49 RS02540
gene id: 1486262:TM49_RS02540
uniprot id: A0A0D5LM17
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS11085
gene id: 1486262:TM49_RS11085
uniprot id: A0A0D5LRV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1486262:TM49 RS10970
gene id: 1486262:TM49_RS10970
uniprot id: A0A0D5LRU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS20985
gene id: 1486262:TM49_RS20985
uniprot id: A0A0D5LTQ2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1486262:TM49 RS12565
gene id: 1486262:TM49_RS12565
uniprot id: A0A0D5LQ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS16220
gene id: 1486262:TM49_RS16220
uniprot id: A0A0D5LS24
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1486262:TM49 RS15515
gene id: 1486262:TM49_RS15515
uniprot id: A0A0D5LS13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1486262:TM49 RS14605
gene id: 1486262:TM49_RS14605
uniprot id: A0A0D5LS77
names: Similarity
messages: Belongs to the AHA1 family.

1486262:TM49 RS04970
gene id: 1486262:TM49_RS04970
uniprot id: A0A0D5LN37
names: Similarity
messages: Belongs to the Tim44 family.

1486262:TM49 RS08665
gene id: 1486262:TM49_RS08665
uniprot id: A0A0D5LND7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1486262:TM49 RS21850
gene id: 1486262:TM49_RS21850
uniprot id: A0A0D5LVC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1486262:TM49 RS05355
gene id: 1486262:TM49_RS05355
uniprot id: A0A0D5LM19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS17855
gene id: 1486262:TM49_RS17855
uniprot id: A0A0D5LWD7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1486262:TM49 RS06975
gene id: 1486262:TM49_RS06975
uniprot id: A0A0D5LNI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1486262:TM49 RS22280
gene id: 1486262:TM49_RS22280
uniprot id: A0A0D5LU75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS05330
gene id: 1486262:TM49_RS05330
uniprot id: A0A0D5LM15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS04750
gene id: 1486262:TM49_RS04750
uniprot id: A0A0D5LMG8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS10885
gene id: 1486262:TM49_RS10885
uniprot id: A0A0D5LPL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1486262:TM49 RS15525
gene id: 1486262:TM49_RS15525
uniprot id: A0A0D5LXT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

1486262:TM49 RS15155
gene id: 1486262:TM49_RS15155
uniprot id: A0A0D5LRF7
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1486262:TM49 RS06055
gene id: 1486262:TM49_RS06055
uniprot id: A0A0D5LPW8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1486262:TM49 RS10545
gene id: 1486262:TM49_RS10545
uniprot id: A0A0D5LRN6
names: Subcellular Location Annotation
messages: Cytoplasm

1486262:TM49 RS18895
gene id: 1486262:TM49_RS18895
uniprot id: A0A0D5LT46
names: Similarity
messages: Belongs to the SCO1/2 family.

1486262:TM49 RS11025
gene id: 1486262:TM49_RS11025
uniprot id: A0A0D5LQP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1486262:TM49 RS20505
gene id: 1486262:TM49_RS20505
uniprot id: A0A0D5LTI9
names: Subcellular Location Annotation
messages: Cytoplasm

1486262:TM49 RS10160
gene id: 1486262:TM49_RS10160
uniprot id: A0A0D5LPV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS11320
gene id: 1486262:TM49_RS11320
uniprot id: A0A0D5LXG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

1486262:TM49 RS08315
gene id: 1486262:TM49_RS08315
uniprot id: A0A0D5LP04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1486262:TM49 RS14840
gene id: 1486262:TM49_RS14840
uniprot id: A0A0D5LWA6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1486262:TM49 RS05185
gene id: 1486262:TM49_RS05185
uniprot id: A0A0D5LN65
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS16645
gene id: 1486262:TM49_RS16645
uniprot id: A0A0D5LSM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1486262:TM49 RS18220
gene id: 1486262:TM49_RS18220
uniprot id: A0A0D5LTS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1486262:TM49 RS05445
gene id: 1486262:TM49_RS05445
uniprot id: A0A0D5LM31
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1486262:TM49 RS06515
gene id: 1486262:TM49_RS06515
uniprot id: A0A0D5LNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS05370
gene id: 1486262:TM49_RS05370
uniprot id: A0A0D5LNA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS14800
gene id: 1486262:TM49_RS14800
uniprot id: A0A0D5LRA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1486262:TM49 RS19380
gene id: 1486262:TM49_RS19380
uniprot id: A0A0D5LT04
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS20585
gene id: 1486262:TM49_RS20585
uniprot id: A0A0D5LTZ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1486262:TM49 RS19740
gene id: 1486262:TM49_RS19740
uniprot id: A0A0D5LUG6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1486262:TM49 RS12835
gene id: 1486262:TM49_RS12835
uniprot id: A0A0D5LQ84
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1486262:TM49 RS10890
gene id: 1486262:TM49_RS10890
uniprot id: A0A0D5LQM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS06135
gene id: 1486262:TM49_RS06135
uniprot id: A0A0D5LPY6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1486262:TM49 RS11095
gene id: 1486262:TM49_RS11095
uniprot id: A0A0D5LQ78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1486262:TM49 RS04575
gene id: 1486262:TM49_RS04575
uniprot id: A0A0D5LP87
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1486262:TM49 RS15005
gene id: 1486262:TM49_RS15005
uniprot id: A0A0D5LTI3
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

1486262:TM49 RS02250
gene id: 1486262:TM49_RS02250
uniprot id: A0A0D5LLW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1486262:TM49 RS07025
gene id: 1486262:TM49_RS07025
uniprot id: A0A0D5LX53
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS09840
gene id: 1486262:TM49_RS09840
uniprot id: A0A0D5LQ75
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

1486262:TM49 RS19550
gene id: 1486262:TM49_RS19550
uniprot id: A0A0D5LVV6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1486262:TM49 RS04605
gene id: 1486262:TM49_RS04605
uniprot id: A0A0D5LLR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS08620
gene id: 1486262:TM49_RS08620
uniprot id: A0A0D5LNL1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1486262:TM49 RS15660
gene id: 1486262:TM49_RS15660
uniprot id: A0A0D5LRL3
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1486262:TM49 RS10605
gene id: 1486262:TM49_RS10605
uniprot id: A0A0D5LRP4
names: Similarity
messages: Belongs to the AHA1 family.

1486262:TM49 RS16010
gene id: 1486262:TM49_RS16010
uniprot id: A0A0D5LRH3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1486262:TM49 RS20630
gene id: 1486262:TM49_RS20630
uniprot id: A0A0D5LVW7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1486262:TM49 RS19865
gene id: 1486262:TM49_RS19865
uniprot id: A0A0D5LVM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1486262:TM49 RS09085
gene id: 1486262:TM49_RS09085
uniprot id: A0A0D5LPV6
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS11355
gene id: 1486262:TM49_RS11355
uniprot id: A0A0D5LQB5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS03110
gene id: 1486262:TM49_RS03110
uniprot id: A0A0D5LLU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1486262:TM49 RS21095
gene id: 1486262:TM49_RS21095
uniprot id: A0A0D5LW35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1486262:TM49 RS13015
gene id: 1486262:TM49_RS13015
uniprot id: A0A0D5LW63
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1486262:TM49 RS19850
gene id: 1486262:TM49_RS19850
uniprot id: A0A0D5LTX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1486262:TM49 RS15835
gene id: 1486262:TM49_RS15835
uniprot id: A0A0D5LRE8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS02350
gene id: 1486262:TM49_RS02350
uniprot id: A0A0D5LLY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1486262:TM49 RS06000
gene id: 1486262:TM49_RS06000
uniprot id: A0A0D5LMA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1486262:TM49 RS14980
gene id: 1486262:TM49_RS14980
uniprot id: A0A0D5LR33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1486262:TM49 RS22130
gene id: 1486262:TM49_RS22130
uniprot id: A0A0D5LWI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS01770
gene id: 1486262:TM49_RS01770
uniprot id: A0A0D5LKL3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS04635
gene id: 1486262:TM49_RS04635
uniprot id: A0A0D5LP95
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS21800
gene id: 1486262:TM49_RS21800
uniprot id: A0A0D5LWB5
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1486262:TM49 RS05385
gene id: 1486262:TM49_RS05385
uniprot id: A0A0D5LMS2
names: Similarity
messages: Belongs to the FGGY kinase family.

1486262:TM49 RS03370
gene id: 1486262:TM49_RS03370
uniprot id: A0A0D5LNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS11820
gene id: 1486262:TM49_RS11820
uniprot id: A0A0D5LQI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1486262:TM49 RS21205
gene id: 1486262:TM49_RS21205
uniprot id: A0A0D5LU83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS04110
gene id: 1486262:TM49_RS04110
uniprot id: A0A0D5LM81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS06310
gene id: 1486262:TM49_RS06310
uniprot id: A0A0D5LQ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1486262:TM49 RS03670
gene id: 1486262:TM49_RS03670
uniprot id: A0A0D5LLC7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS20020
gene id: 1486262:TM49_RS20020
uniprot id: A0A0D5LU03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1486262:TM49 RS14745
gene id: 1486262:TM49_RS14745
uniprot id: A0A0D5LW32
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1486262:TM49 RS11040
gene id: 1486262:TM49_RS11040
uniprot id: A0A0D5LPD9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1486262:TM49 RS14180
gene id: 1486262:TM49_RS14180
uniprot id: A0A0D5LS05
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS14385
gene id: 1486262:TM49_RS14385
uniprot id: A0A0D5LRM2
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

1486262:TM49 RS20230
gene id: 1486262:TM49_RS20230
uniprot id: A0A0D5LTT0
names: Subcellular Location Annotation
messages: Cell inner membrane

1486262:TM49 RS07945
gene id: 1486262:TM49_RS07945
uniprot id: A0A0D5LQK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1486262:TM49 RS07965
gene id: 1486262:TM49_RS07965
uniprot id: A0A0D5LPD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1486262:TM49 RS20945
gene id: 1486262:TM49_RS20945
uniprot id: A0A0D5LW15
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1486262:TM49 RS08840
gene id: 1486262:TM49_RS08840
uniprot id: A0A0D5LNP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1486262:TM49 RS03145
gene id: 1486262:TM49_RS03145
uniprot id: A0A0D5LMC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS15910
gene id: 1486262:TM49_RS15910
uniprot id: A0A0D5LRP5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1486262:TM49 RS21140
gene id: 1486262:TM49_RS21140
uniprot id: A0A0D5LU72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1486262:TM49 RS00750
gene id: 1486262:TM49_RS00750
uniprot id: A0A0D5LK75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS13340
gene id: 1486262:TM49_RS13340
uniprot id: A0A0D5LRQ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS17895
gene id: 1486262:TM49_RS17895
uniprot id: A0A0D5LSQ1
names: Cofactor
messages: Can also use Mn(2+) ion.

1486262:TM49 RS19605
gene id: 1486262:TM49_RS19605
uniprot id: A0A0D5LVI1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1486262:TM49 RS21745
gene id: 1486262:TM49_RS21745
uniprot id: A0A0D5LWA7
names: Similarity
messages: Belongs to the peptidase U62 family.

1486262:TM49 RS18115
gene id: 1486262:TM49_RS18115
uniprot id: A0A0D5LTR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1486262:TM49 RS10750
gene id: 1486262:TM49_RS10750
uniprot id: A0A0D5LP91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1486262:TM49 RS08645
gene id: 1486262:TM49_RS08645
uniprot id: A0A0D5LNL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1486262:TM49 RS08305
gene id: 1486262:TM49_RS08305
uniprot id: A0A0D5LW92
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1486262:TM49 RS08520
gene id: 1486262:TM49_RS08520
uniprot id: A0A0D5LNB5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1486262:TM49 RS19890
gene id: 1486262:TM49_RS19890
uniprot id: A0A0D5LUJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1486262:TM49 RS09350
gene id: 1486262:TM49_RS09350
uniprot id: A0A0D5LVT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS05955
gene id: 1486262:TM49_RS05955
uniprot id: A0A0D5LNI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1486262:TM49 RS20530
gene id: 1486262:TM49_RS20530
uniprot id: A0A0D5LUT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1486262:TM49 RS13210
gene id: 1486262:TM49_RS13210
uniprot id: A0A0D5LRN9
names: Similarity
messages: Belongs to the fructosamine kinase family.

1486262:TM49 RS19975
gene id: 1486262:TM49_RS19975
uniprot id: A0A0D5LVN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1486262:TM49 RS08935
gene id: 1486262:TM49_RS08935
uniprot id: A0A0D5LPU0
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

1486262:TM49 RS20050
gene id: 1486262:TM49_RS20050
uniprot id: A0A0D5LU06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1486262:TM49 RS05260
gene id: 1486262:TM49_RS05260
uniprot id: A0A0D5LMP6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS18195
gene id: 1486262:TM49_RS18195
uniprot id: A0A0D5LTS3
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

1486262:TM49 RS17880
gene id: 1486262:TM49_RS17880
uniprot id: A0A0D5LSD6
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1486262:TM49 RS00980
gene id: 1486262:TM49_RS00980
uniprot id: A0A0D5LLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS10190
gene id: 1486262:TM49_RS10190
uniprot id: A0A0D5LPB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1486262:TM49 RS08930
gene id: 1486262:TM49_RS08930
uniprot id: A0A0D5LXA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1486262:TM49 RS02900
gene id: 1486262:TM49_RS02900
uniprot id: A0A0D5LNL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS08035
gene id: 1486262:TM49_RS08035
uniprot id: A0A0D5LQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS01155
gene id: 1486262:TM49_RS01155
uniprot id: A0A0D5LKW8
names: Similarity
messages: Belongs to the GcvT family.

1486262:TM49 RS16555
gene id: 1486262:TM49_RS16555
uniprot id: A0A0D5LSL1
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1486262:TM49 RS16835
gene id: 1486262:TM49_RS16835
uniprot id: A0A0D5LS11
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1486262:TM49 RS11315
gene id: 1486262:TM49_RS11315
uniprot id: A0A0D5LRY5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS22135
gene id: 1486262:TM49_RS22135
uniprot id: A0A0D5LU56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS21235
gene id: 1486262:TM49_RS21235
uniprot id: A0A0D5LY93
names: Similarity
messages: Belongs to the thioredoxin family.

1486262:TM49 RS11445
gene id: 1486262:TM49_RS11445
uniprot id: A0A0D5LV44
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS18030
gene id: 1486262:TM49_RS18030
uniprot id: A0A0D5LUU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1486262:TM49 RS00175
gene id: 1486262:TM49_RS00175
uniprot id: A0A0D5LMC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS12440
gene id: 1486262:TM49_RS12440
uniprot id: A0A0D5LR98
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS05615
gene id: 1486262:TM49_RS05615
uniprot id: A0A0D5LPN1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1486262:TM49 RS02210
gene id: 1486262:TM49_RS02210
uniprot id: A0A0D5LVA9
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS00710
gene id: 1486262:TM49_RS00710
uniprot id: A0A0D5LK21
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1486262:TM49 RS04915
gene id: 1486262:TM49_RS04915
uniprot id: A0A0D5LMJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS21550
gene id: 1486262:TM49_RS21550
uniprot id: A0A0D5LV82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1486262:TM49 RS05915
gene id: 1486262:TM49_RS05915
uniprot id: A0A0D5LN03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1486262:TM49 RS19910
gene id: 1486262:TM49_RS19910
uniprot id: A0A0D5LTY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1486262:TM49 RS10590
gene id: 1486262:TM49_RS10590
uniprot id: A0A0D5LQ09
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS20885
gene id: 1486262:TM49_RS20885
uniprot id: A0A0D5LW06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1486262:TM49 RS00385
gene id: 1486262:TM49_RS00385
uniprot id: A0A0D5LKL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1486262:TM49 RS13485
gene id: 1486262:TM49_RS13485
uniprot id: A0A0D5LW71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1486262:TM49 RS02420
gene id: 1486262:TM49_RS02420
uniprot id: A0A0D5LLF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS11000
gene id: 1486262:TM49_RS11000
uniprot id: A0A0D5LQP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS12815
gene id: 1486262:TM49_RS12815
uniprot id: A0A0D5LR08
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1486262:TM49 RS07065
gene id: 1486262:TM49_RS07065
uniprot id: A0A0D5LNJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS15770
gene id: 1486262:TM49_RS15770
uniprot id: A0A0D5LTU6
names: Similarity
messages: Belongs to the sulfatase family.

1486262:TM49 RS07055
gene id: 1486262:TM49_RS07055
uniprot id: A0A0D5LQ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS10700
gene id: 1486262:TM49_RS10700
uniprot id: A0A0D5LQ22
names: Similarity
messages: Belongs to the GppA/Ppx family.

1486262:TM49 RS08025
gene id: 1486262:TM49_RS08025
uniprot id: A0A0D5LNC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS04335
gene id: 1486262:TM49_RS04335
uniprot id: A0A0D5LLM2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1486262:TM49 RS11210
gene id: 1486262:TM49_RS11210
uniprot id: A0A0D5LVT2
names: Similarity
messages: Belongs to the UPF0751 family.

1486262:TM49 RS05775
gene id: 1486262:TM49_RS05775
uniprot id: A0A0D5LMC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1486262:TM49 RS20250
gene id: 1486262:TM49_RS20250
uniprot id: A0A0D5LVR7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1486262:TM49 RS11795
gene id: 1486262:TM49_RS11795
uniprot id: A0A0D5LQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BA14k family.
messages: Cell membrane
messages: Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport.
messages: Membrane

1486262:TM49 RS21435
gene id: 1486262:TM49_RS21435
uniprot id: A0A0D5LWW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1486262:TM49 RS00945
gene id: 1486262:TM49_RS00945
uniprot id: A0A0D5LK91
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS16315
gene id: 1486262:TM49_RS16315
uniprot id: A0A0D5LT10
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS20225
gene id: 1486262:TM49_RS20225
uniprot id: A0A0D5LU27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS12520
gene id: 1486262:TM49_RS12520
uniprot id: A0A0D5LSF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1486262:TM49 RS19885
gene id: 1486262:TM49_RS19885
uniprot id: A0A0D5LTN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1486262:TM49 RS02685
gene id: 1486262:TM49_RS02685
uniprot id: A0A0D5LM38
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS21010
gene id: 1486262:TM49_RS21010
uniprot id: A0A0D5LV00
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1486262:TM49 RS02710
gene id: 1486262:TM49_RS02710
uniprot id: A0A0D5LM42
names: Similarity
messages: Belongs to the creatininase superfamily.

1486262:TM49 RS08480
gene id: 1486262:TM49_RS08480
uniprot id: A0A0D5LNJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS15180
gene id: 1486262:TM49_RS15180
uniprot id: A0A0D5LRX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1486262:TM49 RS16630
gene id: 1486262:TM49_RS16630
uniprot id: A0A0D5LUC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1486262:TM49 RS09725
gene id: 1486262:TM49_RS09725
uniprot id: A0A0D5LPP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1486262:TM49 RS15460
gene id: 1486262:TM49_RS15460
uniprot id: A0A0D5LR96
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS17995
gene id: 1486262:TM49_RS17995
uniprot id: A0A0D5LSR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1486262:TM49 RS18310
gene id: 1486262:TM49_RS18310
uniprot id: A0A0D5LSW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1486262:TM49 RS07035
gene id: 1486262:TM49_RS07035
uniprot id: A0A0D5LNJ4
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS14715
gene id: 1486262:TM49_RS14715
uniprot id: A0A0D5LTE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

1486262:TM49 RS19795
gene id: 1486262:TM49_RS19795
uniprot id: A0A0D5LTW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1486262:TM49 RS17710
gene id: 1486262:TM49_RS17710
uniprot id: A0A0D5LTK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1486262:TM49 RS20060
gene id: 1486262:TM49_RS20060
uniprot id: A0A0D5LVX0
names: Similarity
messages: Belongs to the GcvT family.

1486262:TM49 RS08245
gene id: 1486262:TM49_RS08245
uniprot id: A0A0D5LQQ3
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1486262:TM49 RS14425
gene id: 1486262:TM49_RS14425
uniprot id: A0A0D5LTA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1486262:TM49 RS01210
gene id: 1486262:TM49_RS01210
uniprot id: A0A0D5LKD5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS10220
gene id: 1486262:TM49_RS10220
uniprot id: A0A0D5LPB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1486262:TM49 RS02130
gene id: 1486262:TM49_RS02130
uniprot id: A0A0D5LLA3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1486262:TM49 RS07915
gene id: 1486262:TM49_RS07915
uniprot id: A0A0D5LPC3
names: Similarity
messages: Belongs to the Dps family.

1486262:TM49 RS10065
gene id: 1486262:TM49_RS10065
uniprot id: A0A0D5LP94
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1486262:TM49 RS01050
gene id: 1486262:TM49_RS01050
uniprot id: A0A0D5LLD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1486262:TM49 RS04210
gene id: 1486262:TM49_RS04210
uniprot id: A0A0D5LM93
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS12445
gene id: 1486262:TM49_RS12445
uniprot id: A0A0D5LSE5
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS10715
gene id: 1486262:TM49_RS10715
uniprot id: A0A0D5LRR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1486262:TM49 RS05580
gene id: 1486262:TM49_RS05580
uniprot id: A0A0D5LPM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1486262:TM49 RS14630
gene id: 1486262:TM49_RS14630
uniprot id: A0A0D5LR85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1486262:TM49 RS00030
gene id: 1486262:TM49_RS00030
uniprot id: A0A0D5LU92
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1486262:TM49 RS13390
gene id: 1486262:TM49_RS13390
uniprot id: A0A0D5LRR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1486262:TM49 RS00335
gene id: 1486262:TM49_RS00335
uniprot id: A0A0D5LKK9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1486262:TM49 RS20035
gene id: 1486262:TM49_RS20035
uniprot id: A0A0D5LY59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1486262:TM49 RS06980
gene id: 1486262:TM49_RS06980
uniprot id: A0A0D5LMZ1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1486262:TM49 RS14240
gene id: 1486262:TM49_RS14240
uniprot id: A0A0D5LT77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS03825
gene id: 1486262:TM49_RS03825
uniprot id: A0A0D5LLF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS16250
gene id: 1486262:TM49_RS16250
uniprot id: A0A0D5LSG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1486262:TM49 RS19640
gene id: 1486262:TM49_RS19640
uniprot id: A0A0D5LT69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1486262:TM49 RS00600
gene id: 1486262:TM49_RS00600
uniprot id: A0A0D5LMI0
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

1486262:TM49 RS18090
gene id: 1486262:TM49_RS18090
uniprot id: A0A0D5LTQ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1486262:TM49 RS04820
gene id: 1486262:TM49_RS04820
uniprot id: A0A0D5LMH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1486262:TM49 RS21510
gene id: 1486262:TM49_RS21510
uniprot id: A0A0D5LUC4
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

1486262:TM49 RS00990
gene id: 1486262:TM49_RS00990
uniprot id: A0A0D5LK57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS10450
gene id: 1486262:TM49_RS10450
uniprot id: A0A0D5LWF4
names: Subcellular Location Annotation
messages: Mitochondrion

1486262:TM49 RS03785
gene id: 1486262:TM49_RS03785
uniprot id: A0A0D5LNX6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1486262:TM49 RS11190
gene id: 1486262:TM49_RS11190
uniprot id: A0A0D5LQ91
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1486262:TM49 RS12485
gene id: 1486262:TM49_RS12485
uniprot id: A0A0D5LQ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS13315
gene id: 1486262:TM49_RS13315
uniprot id: A0A0D5LV91
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1486262:TM49 RS19620
gene id: 1486262:TM49_RS19620
uniprot id: A0A0D5LTI5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS13510
gene id: 1486262:TM49_RS13510
uniprot id: A0A0D5LSY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS04320
gene id: 1486262:TM49_RS04320
uniprot id: A0A0D5LVY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS21570
gene id: 1486262:TM49_RS21570
uniprot id: A0A0D5LUD0
names: Similarity
messages: Belongs to the YkuD family.

1486262:TM49 RS10250
gene id: 1486262:TM49_RS10250
uniprot id: A0A0D5LPW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS03790
gene id: 1486262:TM49_RS03790
uniprot id: A0A0D5LLE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS09220
gene id: 1486262:TM49_RS09220
uniprot id: A0A0D5LPX7
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1486262:TM49 RS11950
gene id: 1486262:TM49_RS11950
uniprot id: A0A0D5LQ14
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1486262:TM49 RS07480
gene id: 1486262:TM49_RS07480
uniprot id: A0A0D5LN54
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1486262:TM49 RS09050
gene id: 1486262:TM49_RS09050
uniprot id: A0A0D5LR28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS10455
gene id: 1486262:TM49_RS10455
uniprot id: A0A0D5LXE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1486262:TM49 RS10110
gene id: 1486262:TM49_RS10110
uniprot id: A0A0D5LQA9
names: Similarity
messages: Belongs to the peptidase M29 family.

1486262:TM49 RS21665
gene id: 1486262:TM49_RS21665
uniprot id: A0A0D5LUE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1486262:TM49 RS03120
gene id: 1486262:TM49_RS03120
uniprot id: A0A0D5LMC5
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS04930
gene id: 1486262:TM49_RS04930
uniprot id: A0A0D5LN35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS13465
gene id: 1486262:TM49_RS13465
uniprot id: A0A0D5LRB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1486262:TM49 RS22395
gene id: 1486262:TM49_RS22395
uniprot id: A0A0D5LV24
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1486262:TM49 RS03635
gene id: 1486262:TM49_RS03635
uniprot id: A0A0D5LNV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS16650
gene id: 1486262:TM49_RS16650
uniprot id: A0A0D5LS97
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS04375
gene id: 1486262:TM49_RS04375
uniprot id: A0A0D5LLR9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS06940
gene id: 1486262:TM49_RS06940
uniprot id: A0A0D5LNI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1486262:TM49 RS21990
gene id: 1486262:TM49_RS21990
uniprot id: A0A0D5LXB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS03795
gene id: 1486262:TM49_RS03795
uniprot id: A0A0D5LM41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS13430
gene id: 1486262:TM49_RS13430
uniprot id: A0A0D5LSX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1486262:TM49 RS16950
gene id: 1486262:TM49_RS16950
uniprot id: A0A0D5LSR3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS15000
gene id: 1486262:TM49_RS15000
uniprot id: A0A0D5LSD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1486262:TM49 RS00255
gene id: 1486262:TM49_RS00255
uniprot id: A0A0D5LL24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS10790
gene id: 1486262:TM49_RS10790
uniprot id: A0A0D5LQL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1486262:TM49 RS01255
gene id: 1486262:TM49_RS01255
uniprot id: A0A0D5LLH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1486262:TM49 RS12035
gene id: 1486262:TM49_RS12035
uniprot id: A0A0D5LPT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS00550
gene id: 1486262:TM49_RS00550
uniprot id: A0A0D5LK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS19430
gene id: 1486262:TM49_RS19430
uniprot id: A0A0D5LT09
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS21505
gene id: 1486262:TM49_RS21505
uniprot id: A0A0D5LUK9
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

1486262:TM49 RS21590
gene id: 1486262:TM49_RS21590
uniprot id: A0A0D5LTY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1486262:TM49 RS12490
gene id: 1486262:TM49_RS12490
uniprot id: A0A0D5LRA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS05190
gene id: 1486262:TM49_RS05190
uniprot id: A0A0D5LPG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS10820
gene id: 1486262:TM49_RS10820
uniprot id: A0A0D5LQL5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1486262:TM49 RS03050
gene id: 1486262:TM49_RS03050
uniprot id: A0A0D5LL37
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1486262:TM49 RS18120
gene id: 1486262:TM49_RS18120
uniprot id: A0A0D5LUV8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1486262:TM49 RS19115
gene id: 1486262:TM49_RS19115
uniprot id: A0A0D5LSW3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS16425
gene id: 1486262:TM49_RS16425
uniprot id: A0A0D5LRW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS15165
gene id: 1486262:TM49_RS15165
uniprot id: A0A0D5LSF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS08625
gene id: 1486262:TM49_RS08625
uniprot id: A0A0D5LPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1486262:TM49 RS19250
gene id: 1486262:TM49_RS19250
uniprot id: A0A0D5LTL2
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1486262:TM49 RS20825
gene id: 1486262:TM49_RS20825
uniprot id: A0A0D5LUX6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1486262:TM49 RS14520
gene id: 1486262:TM49_RS14520
uniprot id: A0A0D5LS62
names: Similarity
messages: Belongs to the Gfa family.

1486262:TM49 RS05320
gene id: 1486262:TM49_RS05320
uniprot id: A0A0D5LN90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS17705
gene id: 1486262:TM49_RS17705
uniprot id: A0A0D5LSM4
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1486262:TM49 RS14100
gene id: 1486262:TM49_RS14100
uniprot id: A0A0D5LRI7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS12185
gene id: 1486262:TM49_RS12185
uniprot id: A0A0D5LQ42
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS00190
gene id: 1486262:TM49_RS00190
uniprot id: A0A0D5LJZ6
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

1486262:TM49 RS03640
gene id: 1486262:TM49_RS03640
uniprot id: A0A0D5LLC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS05660
gene id: 1486262:TM49_RS05660
uniprot id: A0A0D5LM58
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1486262:TM49 RS00605
gene id: 1486262:TM49_RS00605
uniprot id: A0A0D5LK09
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1486262:TM49 RS02825
gene id: 1486262:TM49_RS02825
uniprot id: A0A0D5LNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS09790
gene id: 1486262:TM49_RS09790
uniprot id: A0A0D5LRF0
names: Similarity
messages: Belongs to the hyi family.

1486262:TM49 RS21565
gene id: 1486262:TM49_RS21565
uniprot id: A0A0D5LUL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS20205
gene id: 1486262:TM49_RS20205
uniprot id: A0A0D5LUP6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1486262:TM49 RS09575
gene id: 1486262:TM49_RS09575
uniprot id: A0A0D5LRC1
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1486262:TM49 RS11560
gene id: 1486262:TM49_RS11560
uniprot id: A0A0D5LS17
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1486262:TM49 RS15195
gene id: 1486262:TM49_RS15195
uniprot id: A0A0D5LTL5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1486262:TM49 RS01850
gene id: 1486262:TM49_RS01850
uniprot id: A0A0D5LLQ7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1486262:TM49 RS19915
gene id: 1486262:TM49_RS19915
uniprot id: A0A0D5LTN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1486262:TM49 RS10915
gene id: 1486262:TM49_RS10915
uniprot id: A0A0D5LWG3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1486262:TM49 RS09635
gene id: 1486262:TM49_RS09635
uniprot id: A0A0D5LPN3
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1486262:TM49 RS16990
gene id: 1486262:TM49_RS16990
uniprot id: A0A0D5LSR8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1486262:TM49 RS03425
gene id: 1486262:TM49_RS03425
uniprot id: A0A0D5LVE1
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1486262:TM49 RS05000
gene id: 1486262:TM49_RS05000
uniprot id: A0A0D5LN42
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1486262:TM49 RS02745
gene id: 1486262:TM49_RS02745
uniprot id: A0A0D5LL02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1486262:TM49 RS02005
gene id: 1486262:TM49_RS02005
uniprot id: A0A0D5LL83
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1486262:TM49 RS02375
gene id: 1486262:TM49_RS02375
uniprot id: A0A0D5LLY8
names: Similarity
messages: Belongs to the aspartokinase family.

1486262:TM49 RS15500
gene id: 1486262:TM49_RS15500
uniprot id: A0A0D5LR99
names: Similarity
messages: Belongs to the UPF0423 family.

1486262:TM49 RS02020
gene id: 1486262:TM49_RS02020
uniprot id: A0A0D5LLT3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1486262:TM49 RS18795
gene id: 1486262:TM49_RS18795
uniprot id: A0A0D5LSS7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1486262:TM49 RS17480
gene id: 1486262:TM49_RS17480
uniprot id: A0A0D5LVK8
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1486262:TM49 RS10385
gene id: 1486262:TM49_RS10385
uniprot id: A0A0D5LP36
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1486262:TM49 RS16530
gene id: 1486262:TM49_RS16530
uniprot id: A0A0D5LSK9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1486262:TM49 RS06910
gene id: 1486262:TM49_RS06910
uniprot id: A0A0D5LUT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS21450
gene id: 1486262:TM49_RS21450
uniprot id: A0A0D5LWQ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1486262:TM49 RS15645
gene id: 1486262:TM49_RS15645
uniprot id: A0A0D5LRB8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1486262:TM49 RS05805
gene id: 1486262:TM49_RS05805
uniprot id: A0A0D5LUQ4
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS18175
gene id: 1486262:TM49_RS18175
uniprot id: A0A0D5LSI1
names: Similarity
messages: Belongs to the Gfa family.

1486262:TM49 RS06840
gene id: 1486262:TM49_RS06840
uniprot id: A0A0D5LMX0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1486262:TM49 RS22200
gene id: 1486262:TM49_RS22200
uniprot id: A0A0D5LWI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS05935
gene id: 1486262:TM49_RS05935
uniprot id: A0A0D5LM96
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1486262:TM49 RS11520
gene id: 1486262:TM49_RS11520
uniprot id: A0A0D5LPK8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1486262:TM49 RS12960
gene id: 1486262:TM49_RS12960
uniprot id: A0A0D5LSQ2
names: Similarity
messages: Belongs to the threonine synthase family.

1486262:TM49 RS01090
gene id: 1486262:TM49_RS01090
uniprot id: A0A0D5LK69
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS11465
gene id: 1486262:TM49_RS11465
uniprot id: A0A0D5LQD0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1486262:TM49 RS05310
gene id: 1486262:TM49_RS05310
uniprot id: A0A0D5LMQ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1486262:TM49 RS03080
gene id: 1486262:TM49_RS03080
uniprot id: A0A0D5LLU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1486262:TM49 RS13940
gene id: 1486262:TM49_RS13940
uniprot id: A0A0D5LQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS16595
gene id: 1486262:TM49_RS16595
uniprot id: A0A0D5LT52
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1486262:TM49 RS20415
gene id: 1486262:TM49_RS20415
uniprot id: A0A0D5LU54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1486262:TM49 RS10195
gene id: 1486262:TM49_RS10195
uniprot id: A0A0D5LQC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1486262:TM49 RS07670
gene id: 1486262:TM49_RS07670
uniprot id: A0A0D5LP93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1486262:TM49 RS20895
gene id: 1486262:TM49_RS20895
uniprot id: A0A0D5LVZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS19770
gene id: 1486262:TM49_RS19770
uniprot id: A0A0D5LTL1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS20805
gene id: 1486262:TM49_RS20805
uniprot id: A0A0D5LWV0
names: Similarity
messages: Belongs to the SDHAF4 family.

1486262:TM49 RS03365
gene id: 1486262:TM49_RS03365
uniprot id: A0A0D5LMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS05780
gene id: 1486262:TM49_RS05780
uniprot id: A0A0D5LNG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1486262:TM49 RS19195
gene id: 1486262:TM49_RS19195
uniprot id: A0A0D5LT88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS05585
gene id: 1486262:TM49_RS05585
uniprot id: A0A0D5LM49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS16255
gene id: 1486262:TM49_RS16255
uniprot id: A0A0D5LS31
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1486262:TM49 RS03380
gene id: 1486262:TM49_RS03380
uniprot id: A0A0D5LUJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS21215
gene id: 1486262:TM49_RS21215
uniprot id: A0A0D5LW52
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1486262:TM49 RS21130
gene id: 1486262:TM49_RS21130
uniprot id: A0A0D5LTR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1486262:TM49 RS05120
gene id: 1486262:TM49_RS05120
uniprot id: A0A0D5LLY2
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS01085
gene id: 1486262:TM49_RS01085
uniprot id: A0A0D5LMP4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS03125
gene id: 1486262:TM49_RS03125
uniprot id: A0A0D5LNN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrF family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1486262:TM49 RS10670
gene id: 1486262:TM49_RS10670
uniprot id: A0A0D5LQ19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1486262:TM49 RS11075
gene id: 1486262:TM49_RS11075
uniprot id: A0A0D5LPN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1486262:TM49 RS21555
gene id: 1486262:TM49_RS21555
uniprot id: A0A0D5LW87
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1486262:TM49 RS07080
gene id: 1486262:TM49_RS07080
uniprot id: A0A0D5LN06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1486262:TM49 RS15490
gene id: 1486262:TM49_RS15490
uniprot id: A0A0D5LW56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1486262:TM49 RS11425
gene id: 1486262:TM49_RS11425
uniprot id: A0A0D5LQC5
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1486262:TM49 RS22025
gene id: 1486262:TM49_RS22025
uniprot id: A0A0D5LUK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS10945
gene id: 1486262:TM49_RS10945
uniprot id: A0A0D5LQ57
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1486262:TM49 RS04050
gene id: 1486262:TM49_RS04050
uniprot id: A0A0D5LM73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS16430
gene id: 1486262:TM49_RS16430
uniprot id: A0A0D5LSJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

1486262:TM49 RS06450
gene id: 1486262:TM49_RS06450
uniprot id: A0A0D5LMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS15150
gene id: 1486262:TM49_RS15150
uniprot id: A0A0D5LRW7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1486262:TM49 RS04270
gene id: 1486262:TM49_RS04270
uniprot id: A0A0D5LP40
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1486262:TM49 RS19495
gene id: 1486262:TM49_RS19495
uniprot id: A0A0D5LWS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1486262:TM49 RS10850
gene id: 1486262:TM49_RS10850
uniprot id: A0A0D5LPK7
names: Similarity
messages: Belongs to the peptidase U62 family.

1486262:TM49 RS13195
gene id: 1486262:TM49_RS13195
uniprot id: A0A0D5LR70
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1486262:TM49 RS04895
gene id: 1486262:TM49_RS04895
uniprot id: A0A0D5LM02
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1486262:TM49 RS11155
gene id: 1486262:TM49_RS11155
uniprot id: A0A0D5LQ86
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1486262:TM49 RS15665
gene id: 1486262:TM49_RS15665
uniprot id: A0A0D5LSM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1486262:TM49 RS09695
gene id: 1486262:TM49_RS09695
uniprot id: A0A0D5LNT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1486262:TM49 RS03055
gene id: 1486262:TM49_RS03055
uniprot id: A0A0D5LLT6
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1486262:TM49 RS10725
gene id: 1486262:TM49_RS10725
uniprot id: A0A0D5LQ27
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1486262:TM49 RS15705
gene id: 1486262:TM49_RS15705
uniprot id: A0A0D5LTT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1486262:TM49 RS05840
gene id: 1486262:TM49_RS05840
uniprot id: A0A0D5LMZ3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1486262:TM49 RS13970
gene id: 1486262:TM49_RS13970
uniprot id: A0A0D5LRY0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS20570
gene id: 1486262:TM49_RS20570
uniprot id: A0A0D5LVV7
names: Similarity
messages: Belongs to the peptidase C40 family.

1486262:TM49 RS16400
gene id: 1486262:TM49_RS16400
uniprot id: A0A0D5LRV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS22105
gene id: 1486262:TM49_RS22105
uniprot id: A0A0D5LWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS01960
gene id: 1486262:TM49_RS01960
uniprot id: A0A0D5LLS2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1486262:TM49 RS20755
gene id: 1486262:TM49_RS20755
uniprot id: A0A0D5LU18
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1486262:TM49 RS10685
gene id: 1486262:TM49_RS10685
uniprot id: A0A0D5LQJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1486262:TM49 RS04410
gene id: 1486262:TM49_RS04410
uniprot id: A0A0D5LLS4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS21070
gene id: 1486262:TM49_RS21070
uniprot id: A0A0D5LW30
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1486262:TM49 RS15700
gene id: 1486262:TM49_RS15700
uniprot id: A0A0D5LSM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1486262:TM49 RS08210
gene id: 1486262:TM49_RS08210
uniprot id: A0A0D5LPH5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1486262:TM49 RS11540
gene id: 1486262:TM49_RS11540
uniprot id: A0A0D5LPV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS14725
gene id: 1486262:TM49_RS14725
uniprot id: A0A0D5LQZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1486262:TM49 RS06465
gene id: 1486262:TM49_RS06465
uniprot id: A0A0D5LNT1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1486262:TM49 RS08310
gene id: 1486262:TM49_RS08310
uniprot id: A0A0D5LN81
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1486262:TM49 RS09910
gene id: 1486262:TM49_RS09910
uniprot id: A0A0D5LNX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS21080
gene id: 1486262:TM49_RS21080
uniprot id: A0A0D5LUE4
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

1486262:TM49 RS21945
gene id: 1486262:TM49_RS21945
uniprot id: A0A0D5LVE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS18480
gene id: 1486262:TM49_RS18480
uniprot id: A0A0D5LV07
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1486262:TM49 RS01815
gene id: 1486262:TM49_RS01815
uniprot id: A0A0D5LLQ3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1486262:TM49 RS16290
gene id: 1486262:TM49_RS16290
uniprot id: A0A0D5LT05
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS08725
gene id: 1486262:TM49_RS08725
uniprot id: A0A0D5LNM8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS21710
gene id: 1486262:TM49_RS21710
uniprot id: A0A0D5LVA5
names: Similarity
messages: Belongs to the YggT family.

1486262:TM49 RS06970
gene id: 1486262:TM49_RS06970
uniprot id: A0A0D5LMR9
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

1486262:TM49 RS16225
gene id: 1486262:TM49_RS16225
uniprot id: A0A0D5LSZ5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1486262:TM49 RS02080
gene id: 1486262:TM49_RS02080
uniprot id: A0A0D5LKP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1486262:TM49 RS07195
gene id: 1486262:TM49_RS07195
uniprot id: A0A0D5LVI0
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS07490
gene id: 1486262:TM49_RS07490
uniprot id: A0A0D5LQE9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1486262:TM49 RS03855
gene id: 1486262:TM49_RS03855
uniprot id: A0A0D5LLF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS10420
gene id: 1486262:TM49_RS10420
uniprot id: A0A0D5LPY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1486262:TM49 RS20545
gene id: 1486262:TM49_RS20545
uniprot id: A0A0D5LU74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1486262:TM49 RS06700
gene id: 1486262:TM49_RS06700
uniprot id: A0A0D5LQ56
names: Similarity
messages: Belongs to the DapA family.

1486262:TM49 RS07060
gene id: 1486262:TM49_RS07060
uniprot id: A0A0D5LMT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS19945
gene id: 1486262:TM49_RS19945
uniprot id: A0A0D5LUK0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1486262:TM49 RS04455
gene id: 1486262:TM49_RS04455
uniprot id: A0A0D5LMW2
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS02575
gene id: 1486262:TM49_RS02575
uniprot id: A0A0D5LKT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS10555
gene id: 1486262:TM49_RS10555
uniprot id: A0A0D5LQ02
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1486262:TM49 RS13420
gene id: 1486262:TM49_RS13420
uniprot id: A0A0D5LQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1486262:TM49 RS15715
gene id: 1486262:TM49_RS15715
uniprot id: A0A0D5LWT5
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1486262:TM49 RS10785
gene id: 1486262:TM49_RS10785
uniprot id: A0A0D5LPJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS08440
gene id: 1486262:TM49_RS08440
uniprot id: A0A0D5LP22
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS07780
gene id: 1486262:TM49_RS07780
uniprot id: A0A0D5LQ14
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1486262:TM49 RS04150
gene id: 1486262:TM49_RS04150
uniprot id: A0A0D5LLN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS08505
gene id: 1486262:TM49_RS08505
uniprot id: A0A0D5LNJ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1486262:TM49 RS14910
gene id: 1486262:TM49_RS14910
uniprot id: A0A0D5LTG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1486262:TM49 RS15085
gene id: 1486262:TM49_RS15085
uniprot id: A0A0D5LRE7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1486262:TM49 RS05625
gene id: 1486262:TM49_RS05625
uniprot id: A0A0D5LM53
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1486262:TM49 RS19580
gene id: 1486262:TM49_RS19580
uniprot id: A0A0D5LTI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1486262:TM49 RS14115
gene id: 1486262:TM49_RS14115
uniprot id: A0A0D5LR06
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1486262:TM49 RS13455
gene id: 1486262:TM49_RS13455
uniprot id: A0A0D5LSX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1486262:TM49 RS08330
gene id: 1486262:TM49_RS08330
uniprot id: A0A0D5LPJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1486262:TM49 RS16165
gene id: 1486262:TM49_RS16165
uniprot id: A0A0D5LS15
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS20030
gene id: 1486262:TM49_RS20030
uniprot id: A0A0D5LUM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1486262:TM49 RS12870
gene id: 1486262:TM49_RS12870
uniprot id: A0A0D5LR20
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1486262:TM49 RS16675
gene id: 1486262:TM49_RS16675
uniprot id: A0A0D5LSA3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1486262:TM49 RS18850
gene id: 1486262:TM49_RS18850
uniprot id: A0A0D5LY22
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1486262:TM49 RS02885
gene id: 1486262:TM49_RS02885
uniprot id: A0A0D5LL56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS19160
gene id: 1486262:TM49_RS19160
uniprot id: A0A0D5LTJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS05670
gene id: 1486262:TM49_RS05670
uniprot id: A0A0D5LMA9
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1486262:TM49 RS08065
gene id: 1486262:TM49_RS08065
uniprot id: A0A0D5LQM2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1486262:TM49 RS02780
gene id: 1486262:TM49_RS02780
uniprot id: A0A0D5LLQ0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1486262:TM49 RS16335
gene id: 1486262:TM49_RS16335
uniprot id: A0A0D5LS47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1486262:TM49 RS06660
gene id: 1486262:TM49_RS06660
uniprot id: A0A0D5LNW5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS19230
gene id: 1486262:TM49_RS19230
uniprot id: A0A0D5LT94
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS04255
gene id: 1486262:TM49_RS04255
uniprot id: A0A0D5LLP9
names: Similarity
messages: Belongs to the RelE toxin family.

1486262:TM49 RS20490
gene id: 1486262:TM49_RS20490
uniprot id: A0A0D5LTX5
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS09115
gene id: 1486262:TM49_RS09115
uniprot id: A0A0D5LPW2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1486262:TM49 RS19175
gene id: 1486262:TM49_RS19175
uniprot id: A0A0D5LV92
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1486262:TM49 RS16245
gene id: 1486262:TM49_RS16245
uniprot id: A0A0D5LRS9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1486262:TM49 RS03130
gene id: 1486262:TM49_RS03130
uniprot id: A0A0D5LL51
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1486262:TM49 RS02625
gene id: 1486262:TM49_RS02625
uniprot id: A0A0D5LM28
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS05150
gene id: 1486262:TM49_RS05150
uniprot id: A0A0D5LPG2
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS20690
gene id: 1486262:TM49_RS20690
uniprot id: A0A0D5LUA0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1486262:TM49 RS10075
gene id: 1486262:TM49_RS10075
uniprot id: A0A0D5LQA4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alphaproteobacteria porin family.
messages: Cell outer membrane
messages: Consists of 16-stranded beta-barrel sheets, with large surface-exposed loops, that form a transmembrane pore at the center of each barrel. The pore is partially ocluded by a peptide loop that folds into the pore lumen.
messages: Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.

1486262:TM49 RS02650
gene id: 1486262:TM49_RS02650
uniprot id: A0A0D5LKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS08140
gene id: 1486262:TM49_RS08140
uniprot id: A0A0D5LN53
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS11225
gene id: 1486262:TM49_RS11225
uniprot id: A0A0D5LQ96
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

1486262:TM49 RS18100
gene id: 1486262:TM49_RS18100
uniprot id: A0A0D5LSH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1486262:TM49 RS02410
gene id: 1486262:TM49_RS02410
uniprot id: A0A0D5LNA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS03770
gene id: 1486262:TM49_RS03770
uniprot id: A0A0D5LLI4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1486262:TM49 RS05990
gene id: 1486262:TM49_RS05990
uniprot id: A0A0D5LVD9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1486262:TM49 RS15760
gene id: 1486262:TM49_RS15760
uniprot id: A0A0D5LSN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS19895
gene id: 1486262:TM49_RS19895
uniprot id: A0A0D5LVM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1486262:TM49 RS01760
gene id: 1486262:TM49_RS01760
uniprot id: A0A0D5LKG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS12790
gene id: 1486262:TM49_RS12790
uniprot id: A0A0D5LQZ9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1486262:TM49 RS11185
gene id: 1486262:TM49_RS11185
uniprot id: A0A0D5LPG5
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1486262:TM49 RS09005
gene id: 1486262:TM49_RS09005
uniprot id: A0A0D5LPU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1486262:TM49 RS10330
gene id: 1486262:TM49_RS10330
uniprot id: A0A0D5LPD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1486262:TM49 RS11745
gene id: 1486262:TM49_RS11745
uniprot id: A0A0D5LR02
names: Similarity
messages: Belongs to the sulfatase family.

1486262:TM49 RS11705
gene id: 1486262:TM49_RS11705
uniprot id: A0A0D5LPX8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1486262:TM49 RS15315
gene id: 1486262:TM49_RS15315
uniprot id: A0A0D5LRH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1486262:TM49 RS09240
gene id: 1486262:TM49_RS09240
uniprot id: A0A0D5LNV7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1486262:TM49 RS21640
gene id: 1486262:TM49_RS21640
uniprot id: A0A0D5LUD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1486262:TM49 RS09750
gene id: 1486262:TM49_RS09750
uniprot id: A0A0D5LQ62
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS16395
gene id: 1486262:TM49_RS16395
uniprot id: A0A0D5LU85
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1486262:TM49 RS08295
gene id: 1486262:TM49_RS08295
uniprot id: A0A0D5LPI7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1486262:TM49 RS00260
gene id: 1486262:TM49_RS00260
uniprot id: A0A0D5LMD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS01320
gene id: 1486262:TM49_RS01320
uniprot id: A0A0D5LKA6
names: Subcellular Location Annotation
messages: Cell inner membrane

1486262:TM49 RS05210
gene id: 1486262:TM49_RS05210
uniprot id: A0A0D5LN70
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS19665
gene id: 1486262:TM49_RS19665
uniprot id: A0A0D5LT75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS22300
gene id: 1486262:TM49_RS22300
uniprot id: A0A0D5LWJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1486262:TM49 RS15095
gene id: 1486262:TM49_RS15095
uniprot id: A0A0D5LTJ9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1486262:TM49 RS21610
gene id: 1486262:TM49_RS21610
uniprot id: A0A0D5LV89
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS15850
gene id: 1486262:TM49_RS15850
uniprot id: A0A0D5LSP9
names: Similarity
messages: Belongs to the RutC family.

1486262:TM49 RS08470
gene id: 1486262:TM49_RS08470
uniprot id: A0A0D5LW96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS06555
gene id: 1486262:TM49_RS06555
uniprot id: A0A0D5LQ33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1486262:TM49 RS08680
gene id: 1486262:TM49_RS08680
uniprot id: A0A0D5LPP5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS20640
gene id: 1486262:TM49_RS20640
uniprot id: A0A0D5LU89
names: Similarity
messages: Belongs to the TPP enzyme family.

1486262:TM49 RS05860
gene id: 1486262:TM49_RS05860
uniprot id: A0A0D5LVD5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS18735
gene id: 1486262:TM49_RS18735
uniprot id: A0A0D5LTE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1486262:TM49 RS04085
gene id: 1486262:TM49_RS04085
uniprot id: A0A0D5LM76
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1486262:TM49 RS06015
gene id: 1486262:TM49_RS06015
uniprot id: A0A0D5LNL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1486262:TM49 RS15360
gene id: 1486262:TM49_RS15360
uniprot id: A0A0D5LRI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS22335
gene id: 1486262:TM49_RS22335
uniprot id: A0A0D5LWK2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1486262:TM49 RS11065
gene id: 1486262:TM49_RS11065
uniprot id: A0A0D5LPE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1486262:TM49 RS12140
gene id: 1486262:TM49_RS12140
uniprot id: A0A0D5LQM8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1486262:TM49 RS07955
gene id: 1486262:TM49_RS07955
uniprot id: A0A0D5LNU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1486262:TM49 RS07935
gene id: 1486262:TM49_RS07935
uniprot id: A0A0D5LNB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1486262:TM49 RS02720
gene id: 1486262:TM49_RS02720
uniprot id: A0A0D5LKW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS14225
gene id: 1486262:TM49_RS14225
uniprot id: A0A0D5LR24
names: Similarity
messages: Belongs to the DEAD box helicase family.

1486262:TM49 RS11740
gene id: 1486262:TM49_RS11740
uniprot id: A0A0D5LPY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS08040
gene id: 1486262:TM49_RS08040
uniprot id: A0A0D5LN39
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1486262:TM49 RS17965
gene id: 1486262:TM49_RS17965
uniprot id: A0A0D5LTP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS14600
gene id: 1486262:TM49_RS14600
uniprot id: A0A0D5LR81
names: Similarity
messages: Belongs to the TPP enzyme family.

1486262:TM49 RS02565
gene id: 1486262:TM49_RS02565
uniprot id: A0A0D5LM22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS20785
gene id: 1486262:TM49_RS20785
uniprot id: A0A0D5LUX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS22030
gene id: 1486262:TM49_RS22030
uniprot id: A0A0D5LVF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS07435
gene id: 1486262:TM49_RS07435
uniprot id: A0A0D5LNN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1486262:TM49 RS09990
gene id: 1486262:TM49_RS09990
uniprot id: A0A0D5LP84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS21145
gene id: 1486262:TM49_RS21145
uniprot id: A0A0D5LV16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1486262:TM49 RS01270
gene id: 1486262:TM49_RS01270
uniprot id: A0A0D5LKY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

1486262:TM49 RS01275
gene id: 1486262:TM49_RS01275
uniprot id: A0A0D5LKE5
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS19720
gene id: 1486262:TM49_RS19720
uniprot id: A0A0D5LT84
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS19650
gene id: 1486262:TM49_RS19650
uniprot id: A0A0D5LTJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1486262:TM49 RS15710
gene id: 1486262:TM49_RS15710
uniprot id: A0A0D5LRC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1486262:TM49 RS20120
gene id: 1486262:TM49_RS20120
uniprot id: A0A0D5LVQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS19675
gene id: 1486262:TM49_RS19675
uniprot id: A0A0D5LTJ6
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS18910
gene id: 1486262:TM49_RS18910
uniprot id: A0A0D5LSU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS10965
gene id: 1486262:TM49_RS10965
uniprot id: A0A0D5LXF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1486262:TM49 RS01995
gene id: 1486262:TM49_RS01995
uniprot id: A0A0D5LN38
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1486262:TM49 RS11800
gene id: 1486262:TM49_RS11800
uniprot id: A0A0D5LPZ4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1486262:TM49 RS09080
gene id: 1486262:TM49_RS09080
uniprot id: A0A0D5LNT0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS05880
gene id: 1486262:TM49_RS05880
uniprot id: A0A0D5LMD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS03865
gene id: 1486262:TM49_RS03865
uniprot id: A0A0D5LVE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1486262:TM49 RS06010
gene id: 1486262:TM49_RS06010
uniprot id: A0A0D5LMI1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS13470
gene id: 1486262:TM49_RS13470
uniprot id: A0A0D5LQS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1486262:TM49 RS16660
gene id: 1486262:TM49_RS16660
uniprot id: A0A0D5LUC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1486262:TM49 RS06880
gene id: 1486262:TM49_RS06880
uniprot id: A0A0D5LQ77
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1486262:TM49 RS10070
gene id: 1486262:TM49_RS10070
uniprot id: A0A0D5LWE7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1486262:TM49 RS10375
gene id: 1486262:TM49_RS10375
uniprot id: A0A0D5LQE8
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

1486262:TM49 RS19950
gene id: 1486262:TM49_RS19950
uniprot id: A0A0D5LVN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1486262:TM49 RS09235
gene id: 1486262:TM49_RS09235
uniprot id: A0A0D5LPF7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS21400
gene id: 1486262:TM49_RS21400
uniprot id: A0A0D5LW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1486262:TM49 RS16625
gene id: 1486262:TM49_RS16625
uniprot id: A0A0D5LT59
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1486262:TM49 RS18720
gene id: 1486262:TM49_RS18720
uniprot id: A0A0D5LU04
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS11020
gene id: 1486262:TM49_RS11020
uniprot id: A0A0D5LPM7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1486262:TM49 RS16205
gene id: 1486262:TM49_RS16205
uniprot id: A0A0D5LU48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1486262:TM49 RS00765
gene id: 1486262:TM49_RS00765
uniprot id: A0A0D5LLA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS18060
gene id: 1486262:TM49_RS18060
uniprot id: A0A0D5LTQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1486262:TM49 RS19855
gene id: 1486262:TM49_RS19855
uniprot id: A0A0D5LTM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1486262:TM49 RS16575
gene id: 1486262:TM49_RS16575
uniprot id: A0A0D5LW74
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1486262:TM49 RS16385
gene id: 1486262:TM49_RS16385
uniprot id: A0A0D5LS55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1486262:TM49 RS04910
gene id: 1486262:TM49_RS04910
uniprot id: A0A0D5LLV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1486262:TM49 RS09355
gene id: 1486262:TM49_RS09355
uniprot id: A0A0D5LNL7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS17805
gene id: 1486262:TM49_RS17805
uniprot id: A0A0D5LUS1
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1486262:TM49 RS21165
gene id: 1486262:TM49_RS21165
uniprot id: A0A0D5LUF8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS16460
gene id: 1486262:TM49_RS16460
uniprot id: A0A0D5LRW4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1486262:TM49 RS04925
gene id: 1486262:TM49_RS04925
uniprot id: A0A0D5LM06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1486262:TM49 RS08105
gene id: 1486262:TM49_RS08105
uniprot id: A0A0D5LN47
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1486262:TM49 RS03315
gene id: 1486262:TM49_RS03315
uniprot id: A0A0D5LLB6
names: Similarity
messages: Belongs to the DapA family.

1486262:TM49 RS21950
gene id: 1486262:TM49_RS21950
uniprot id: A0A0D5LWD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS11625
gene id: 1486262:TM49_RS11625
uniprot id: A0A0D5LPM2
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

1486262:TM49 RS06950
gene id: 1486262:TM49_RS06950
uniprot id: A0A0D5LP00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS00045
gene id: 1486262:TM49_RS00045
uniprot id: A0A0D5LJR6
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS21480
gene id: 1486262:TM49_RS21480
uniprot id: A0A0D5LUC0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1486262:TM49 RS12475
gene id: 1486262:TM49_RS12475
uniprot id: A0A0D5LPZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS14680
gene id: 1486262:TM49_RS14680
uniprot id: A0A0D5LTE1
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS12575
gene id: 1486262:TM49_RS12575
uniprot id: A0A0D5LWJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS12955
gene id: 1486262:TM49_RS12955
uniprot id: A0A0D5LRK7
names: Similarity
messages: Belongs to the peptidase M16 family.

1486262:TM49 RS19980
gene id: 1486262:TM49_RS19980
uniprot id: A0A0D5LTC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1486262:TM49 RS00485
gene id: 1486262:TM49_RS00485
uniprot id: A0A0D5LJY8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1486262:TM49 RS03160
gene id: 1486262:TM49_RS03160
uniprot id: A0A0D5LV52
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family.

1486262:TM49 RS10680
gene id: 1486262:TM49_RS10680
uniprot id: A0A0D5LVY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1486262:TM49 RS14595
gene id: 1486262:TM49_RS14595
uniprot id: A0A0D5LRQ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1486262:TM49 RS02930
gene id: 1486262:TM49_RS02930
uniprot id: A0A0D5LL61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS13250
gene id: 1486262:TM49_RS13250
uniprot id: A0A0D5LW67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS01910
gene id: 1486262:TM49_RS01910
uniprot id: A0A0D5LL68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1486262:TM49 RS11905
gene id: 1486262:TM49_RS11905
uniprot id: A0A0D5LQ10
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1486262:TM49 RS18290
gene id: 1486262:TM49_RS18290
uniprot id: A0A0D5LTT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1486262:TM49 RS04525
gene id: 1486262:TM49_RS04525
uniprot id: A0A0D5LMD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS04315
gene id: 1486262:TM49_RS04315
uniprot id: A0A0D5LLQ9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS02385
gene id: 1486262:TM49_RS02385
uniprot id: A0A0D5LKQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1486262:TM49 RS07165
gene id: 1486262:TM49_RS07165
uniprot id: A0A0D5LN16
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1486262:TM49 RS01385
gene id: 1486262:TM49_RS01385
uniprot id: A0A0D5LKB5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1486262:TM49 RS21905
gene id: 1486262:TM49_RS21905
uniprot id: A0A0D5LUT2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS17120
gene id: 1486262:TM49_RS17120
uniprot id: A0A0D5LUI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS06115
gene id: 1486262:TM49_RS06115
uniprot id: A0A0D5LMF7
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1486262:TM49 RS17750
gene id: 1486262:TM49_RS17750
uniprot id: A0A0D5LT03
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1486262:TM49 RS17070
gene id: 1486262:TM49_RS17070
uniprot id: A0A0D5LS44
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1486262:TM49 RS20580
gene id: 1486262:TM49_RS20580
uniprot id: A0A0D5LU79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS13445
gene id: 1486262:TM49_RS13445
uniprot id: A0A0D5LQS3
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1486262:TM49 RS13310
gene id: 1486262:TM49_RS13310
uniprot id: A0A0D5LRQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1486262:TM49 RS16765
gene id: 1486262:TM49_RS16765
uniprot id: A0A0D5LS03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1486262:TM49 RS14575
gene id: 1486262:TM49_RS14575
uniprot id: A0A0D5LR75
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1486262:TM49 RS19375
gene id: 1486262:TM49_RS19375
uniprot id: A0A0D5LVC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1486262:TM49 RS20535
gene id: 1486262:TM49_RS20535
uniprot id: A0A0D5LVV5
names: Similarity
messages: Belongs to the UPF0262 family.

1486262:TM49 RS12905
gene id: 1486262:TM49_RS12905
uniprot id: A0A0D5LR25
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1486262:TM49 RS21180
gene id: 1486262:TM49_RS21180
uniprot id: A0A0D5LW48
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1486262:TM49 RS05850
gene id: 1486262:TM49_RS05850
uniprot id: A0A0D5LNG9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1486262:TM49 RS11385
gene id: 1486262:TM49_RS11385
uniprot id: A0A0D5LPJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

1486262:TM49 RS02655
gene id: 1486262:TM49_RS02655
uniprot id: A0A0D5LM33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS18775
gene id: 1486262:TM49_RS18775
uniprot id: A0A0D5LU11
names: Similarity
messages: Belongs to the RelE toxin family.

1486262:TM49 RS12850
gene id: 1486262:TM49_RS12850
uniprot id: A0A0D5LRJ4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1486262:TM49 RS17640
gene id: 1486262:TM49_RS17640
uniprot id: A0A0D5LSY4
names: Similarity
messages: Belongs to the RecJ family.

1486262:TM49 RS23995
gene id: 1486262:TM49_RS23995
uniprot id: A0A0D5LSQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1486262:TM49 RS11340
gene id: 1486262:TM49_RS11340
uniprot id: A0A0D5LQU9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS11050
gene id: 1486262:TM49_RS11050
uniprot id: A0A0D5LPN2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1486262:TM49 RS11690
gene id: 1486262:TM49_RS11690
uniprot id: A0A0D5LPN4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1486262:TM49 RS08895
gene id: 1486262:TM49_RS08895
uniprot id: A0A0D5LNQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1486262:TM49 RS13140
gene id: 1486262:TM49_RS13140
uniprot id: A0A0D5LQM0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1486262:TM49 RS06665
gene id: 1486262:TM49_RS06665
uniprot id: A0A0D5LQ53
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS04880
gene id: 1486262:TM49_RS04880
uniprot id: A0A0D5LLU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1486262:TM49 RS02605
gene id: 1486262:TM49_RS02605
uniprot id: A0A0D5LLI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS10445
gene id: 1486262:TM49_RS10445
uniprot id: A0A0D5LVR3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1486262:TM49 RS06315
gene id: 1486262:TM49_RS06315
uniprot id: A0A0D5LMI2
names: Similarity
messages: Belongs to the SlyX family.

1486262:TM49 RS00895
gene id: 1486262:TM49_RS00895
uniprot id: A0A0D5LLB8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1486262:TM49 RS20495
gene id: 1486262:TM49_RS20495
uniprot id: A0A0D5LUT5
names: Similarity
messages: Belongs to the universal stress protein A family.

1486262:TM49 RS19655
gene id: 1486262:TM49_RS19655
uniprot id: A0A0D5LUF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1486262:TM49 RS11345
gene id: 1486262:TM49_RS11345
uniprot id: A0A0D5LRZ0
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

1486262:TM49 RS15905
gene id: 1486262:TM49_RS15905
uniprot id: A0A0D5LS79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1486262:TM49 RS20850
gene id: 1486262:TM49_RS20850
uniprot id: A0A0D5LTN9
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1486262:TM49 RS14410
gene id: 1486262:TM49_RS14410
uniprot id: A0A0D5LRM6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1486262:TM49 RS12680
gene id: 1486262:TM49_RS12680
uniprot id: A0A0D5LV76
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M81 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC).

1486262:TM49 RS11175
gene id: 1486262:TM49_RS11175
uniprot id: A0A0D5LQS2
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS13175
gene id: 1486262:TM49_RS13175
uniprot id: A0A0D5LXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS09095
gene id: 1486262:TM49_RS09095
uniprot id: A0A0D5LR32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1486262:TM49 RS02225
gene id: 1486262:TM49_RS02225
uniprot id: A0A0D5LKN5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1486262:TM49 RS17035
gene id: 1486262:TM49_RS17035
uniprot id: A0A0D5LUH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS19745
gene id: 1486262:TM49_RS19745
uniprot id: A0A0D5LVK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1486262:TM49 RS02045
gene id: 1486262:TM49_RS02045
uniprot id: A0A0D5LL89
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-58 and Arg-61) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1486262:TM49 RS14950
gene id: 1486262:TM49_RS14950
uniprot id: A0A0D5LRU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1486262:TM49 RS02550
gene id: 1486262:TM49_RS02550
uniprot id: A0A0D5LKT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1486262:TM49 RS21995
gene id: 1486262:TM49_RS21995
uniprot id: A0A0D5LUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS17730
gene id: 1486262:TM49_RS17730
uniprot id: A0A0D5LSM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1486262:TM49 RS08485
gene id: 1486262:TM49_RS08485
uniprot id: A0A0D5LPL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS09875
gene id: 1486262:TM49_RS09875
uniprot id: A0A0D5LVV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS18105
gene id: 1486262:TM49_RS18105
uniprot id: A0A0D5LT50
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1486262:TM49 RS00330
gene id: 1486262:TM49_RS00330
uniprot id: A0A0D5LJW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1486262:TM49 RS11760
gene id: 1486262:TM49_RS11760
uniprot id: A0A0D5LQH0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1486262:TM49 RS12545
gene id: 1486262:TM49_RS12545
uniprot id: A0A0D5LRB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS16195
gene id: 1486262:TM49_RS16195
uniprot id: A0A0D5LS20
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1486262:TM49 RS08275
gene id: 1486262:TM49_RS08275
uniprot id: A0A0D5LN76
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1486262:TM49 RS11105
gene id: 1486262:TM49_RS11105
uniprot id: A0A0D5LQR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1486262:TM49 RS19900
gene id: 1486262:TM49_RS19900
uniprot id: A0A0D5LTB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1486262:TM49 RS00200
gene id: 1486262:TM49_RS00200
uniprot id: A0A0D5LVL1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS05940
gene id: 1486262:TM49_RS05940
uniprot id: A0A0D5LVJ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS15605
gene id: 1486262:TM49_RS15605
uniprot id: A0A0D5LTR9
names: Similarity
messages: Belongs to the NifX/NifY family.

1486262:TM49 RS17675
gene id: 1486262:TM49_RS17675
uniprot id: A0A0D5LTJ7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1486262:TM49 RS16410
gene id: 1486262:TM49_RS16410
uniprot id: A0A0D5LS58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1486262:TM49 RS21520
gene id: 1486262:TM49_RS21520
uniprot id: A0A0D5LW83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1486262:TM49 RS01880
gene id: 1486262:TM49_RS01880
uniprot id: A0A0D5LLR2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1486262:TM49 RS06935
gene id: 1486262:TM49_RS06935
uniprot id: A0A0D5LMR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS08500
gene id: 1486262:TM49_RS08500
uniprot id: A0A0D5LP34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1486262:TM49 RS07110
gene id: 1486262:TM49_RS07110
uniprot id: A0A0D5LNK1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1486262:TM49 RS12975
gene id: 1486262:TM49_RS12975
uniprot id: A0A0D5LQI9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1486262:TM49 RS08385
gene id: 1486262:TM49_RS08385
uniprot id: A0A0D5LP13
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1486262:TM49 RS07050
gene id: 1486262:TM49_RS07050
uniprot id: A0A0D5LUT7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1486262:TM49 RS14390
gene id: 1486262:TM49_RS14390
uniprot id: A0A0D5LR49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1486262:TM49 RS12560
gene id: 1486262:TM49_RS12560
uniprot id: A0A0D5LSG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS19155
gene id: 1486262:TM49_RS19155
uniprot id: A0A0D5LSX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS01745
gene id: 1486262:TM49_RS01745
uniprot id: A0A0D5LN07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS21200
gene id: 1486262:TM49_RS21200
uniprot id: A0A0D5LUG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1486262:TM49 RS15690
gene id: 1486262:TM49_RS15690
uniprot id: A0A0D5LS38
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1486262:TM49 RS18635
gene id: 1486262:TM49_RS18635
uniprot id: A0A0D5LV32
names: Similarity
messages: Belongs to the UPF0260 family.

1486262:TM49 RS04565
gene id: 1486262:TM49_RS04565
uniprot id: A0A0D5LMY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS20110
gene id: 1486262:TM49_RS20110
uniprot id: A0A0D5LUN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1486262:TM49 RS05575
gene id: 1486262:TM49_RS05575
uniprot id: A0A0D5LVC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1486262:TM49 RS08400
gene id: 1486262:TM49_RS08400
uniprot id: A0A0D5LQT0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1486262:TM49 RS14005
gene id: 1486262:TM49_RS14005
uniprot id: A0A0D5LXM7
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1486262:TM49 RS08915
gene id: 1486262:TM49_RS08915
uniprot id: A0A0D5LNH4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1486262:TM49 RS12695
gene id: 1486262:TM49_RS12695
uniprot id: A0A0D5LQW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS16280
gene id: 1486262:TM49_RS16280
uniprot id: A0A0D5LSH2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1486262:TM49 RS10995
gene id: 1486262:TM49_RS10995
uniprot id: A0A0D5LPM3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1486262:TM49 RS22285
gene id: 1486262:TM49_RS22285
uniprot id: A0A0D5LV11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS13235
gene id: 1486262:TM49_RS13235
uniprot id: A0A0D5LQN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS15415
gene id: 1486262:TM49_RS15415
uniprot id: A0A0D5LXS8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1486262:TM49 RS00210
gene id: 1486262:TM49_RS00210
uniprot id: A0A0D5LJU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1486262:TM49 RS02140
gene id: 1486262:TM49_RS02140
uniprot id: A0A0D5LLV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

1486262:TM49 RS18725
gene id: 1486262:TM49_RS18725
uniprot id: A0A0D5LV41
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS14255
gene id: 1486262:TM49_RS14255
uniprot id: A0A0D5LR29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS02560
gene id: 1486262:TM49_RS02560
uniprot id: A0A0D5LKX7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS17735
gene id: 1486262:TM49_RS17735
uniprot id: A0A0D5LTK8
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1486262:TM49 RS04535
gene id: 1486262:TM49_RS04535
uniprot id: A0A0D5LMX9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS15830
gene id: 1486262:TM49_RS15830
uniprot id: A0A0D5LTV5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS01295
gene id: 1486262:TM49_RS01295
uniprot id: A0A0D5LKA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS04590
gene id: 1486262:TM49_RS04590
uniprot id: A0A0D5LLV6
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1486262:TM49 RS06585
gene id: 1486262:TM49_RS06585
uniprot id: A0A0D5LQ39
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

1486262:TM49 RS15325
gene id: 1486262:TM49_RS15325
uniprot id: A0A0D5LWS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1486262:TM49 RS04845
gene id: 1486262:TM49_RS04845
uniprot id: A0A0D5LMI3
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

1486262:TM49 RS12555
gene id: 1486262:TM49_RS12555
uniprot id: A0A0D5LVW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS13605
gene id: 1486262:TM49_RS13605
uniprot id: A0A0D5LRU1
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1486262:TM49 RS06530
gene id: 1486262:TM49_RS06530
uniprot id: A0A0D5LQ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS08030
gene id: 1486262:TM49_RS08030
uniprot id: A0A0D5LPE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS10320
gene id: 1486262:TM49_RS10320
uniprot id: A0A0D5LP26
names: Subunit
messages: Homodimer.

1486262:TM49 RS18185
gene id: 1486262:TM49_RS18185
uniprot id: A0A0D5LSU8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS15265
gene id: 1486262:TM49_RS15265
uniprot id: A0A0D5LTM6
names: Similarity
messages: Belongs to the RNase T2 family.

1486262:TM49 RS05965
gene id: 1486262:TM49_RS05965
uniprot id: A0A0D5LMA1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1486262:TM49 RS22090
gene id: 1486262:TM49_RS22090
uniprot id: A0A0D5LUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS01430
gene id: 1486262:TM49_RS01430
uniprot id: A0A0D5LLK5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1486262:TM49 RS18265
gene id: 1486262:TM49_RS18265
uniprot id: A0A0D5LSJ7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS04595
gene id: 1486262:TM49_RS04595
uniprot id: A0A0D5LMY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS20675
gene id: 1486262:TM49_RS20675
uniprot id: A0A0D5LUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS19860
gene id: 1486262:TM49_RS19860
uniprot id: A0A0D5LUI6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1486262:TM49 RS17485
gene id: 1486262:TM49_RS17485
uniprot id: A0A0D5LQ14
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1486262:TM49 RS15745
gene id: 1486262:TM49_RS15745
uniprot id: A0A0D5LS46
names: Similarity
messages: Belongs to the pirin family.

1486262:TM49 RS16350
gene id: 1486262:TM49_RS16350
uniprot id: A0A0D5LRU8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1486262:TM49 RS03730
gene id: 1486262:TM49_RS03730
uniprot id: A0A0D5LVX3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1486262:TM49 RS08775
gene id: 1486262:TM49_RS08775
uniprot id: A0A0D5LNF7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1486262:TM49 RS03575
gene id: 1486262:TM49_RS03575
uniprot id: A0A0D5LM13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YtcA family.
messages: Membrane

1486262:TM49 RS06575
gene id: 1486262:TM49_RS06575
uniprot id: A0A0D5LMS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1486262:TM49 RS04875
gene id: 1486262:TM49_RS04875
uniprot id: A0A0D5LPC8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1486262:TM49 RS20370
gene id: 1486262:TM49_RS20370
uniprot id: A0A0D5LTH2
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1486262:TM49 RS21015
gene id: 1486262:TM49_RS21015
uniprot id: A0A0D5LW25
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS14260
gene id: 1486262:TM49_RS14260
uniprot id: A0A0D5LS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS02290
gene id: 1486262:TM49_RS02290
uniprot id: A0A0D5LKP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1486262:TM49 RS05465
gene id: 1486262:TM49_RS05465
uniprot id: A0A0D5LNB4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS20160
gene id: 1486262:TM49_RS20160
uniprot id: A0A0D5LU19
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1486262:TM49 RS21730
gene id: 1486262:TM49_RS21730
uniprot id: A0A0D5LUQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1486262:TM49 RS14570
gene id: 1486262:TM49_RS14570
uniprot id: A0A0D5LVB1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1486262:TM49 RS19940
gene id: 1486262:TM49_RS19940
uniprot id: A0A0D5LTP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1486262:TM49 RS00795
gene id: 1486262:TM49_RS00795
uniprot id: A0A0D5LK32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS12665
gene id: 1486262:TM49_RS12665
uniprot id: A0A0D5LQA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1486262:TM49 RS01860
gene id: 1486262:TM49_RS01860
uniprot id: A0A0D5LKI3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1486262:TM49 RS18515
gene id: 1486262:TM49_RS18515
uniprot id: A0A0D5LTB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1486262:TM49 RS03440
gene id: 1486262:TM49_RS03440
uniprot id: A0A0D5LV62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS17065
gene id: 1486262:TM49_RS17065
uniprot id: A0A0D5LUH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1486262:TM49 RS02285
gene id: 1486262:TM49_RS02285
uniprot id: A0A0D5LN82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS02025
gene id: 1486262:TM49_RS02025
uniprot id: A0A0D5LN43
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1486262:TM49 RS09985
gene id: 1486262:TM49_RS09985
uniprot id: A0A0D5LPT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS03680
gene id: 1486262:TM49_RS03680
uniprot id: A0A0D5LLG7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1486262:TM49 RS19340
gene id: 1486262:TM49_RS19340
uniprot id: A0A0D5LU86
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1486262:TM49 RS04170
gene id: 1486262:TM49_RS04170
uniprot id: A0A0D5LVY3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1486262:TM49 RS00950
gene id: 1486262:TM49_RS00950
uniprot id: A0A0D5LLC4
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS13070
gene id: 1486262:TM49_RS13070
uniprot id: A0A0D5LVY8
names: Similarity
messages: Belongs to the peptidase M1 family.

1486262:TM49 RS00475
gene id: 1486262:TM49_RS00475
uniprot id: A0A0D5LL57
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1486262:TM49 RS18435
gene id: 1486262:TM49_RS18435
uniprot id: A0A0D5LXZ1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1486262:TM49 RS05125
gene id: 1486262:TM49_RS05125
uniprot id: A0A0D5LMM5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS02920
gene id: 1486262:TM49_RS02920
uniprot id: A0A0D5LLS1
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1486262:TM49 RS05655
gene id: 1486262:TM49_RS05655
uniprot id: A0A0D5LPN5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1486262:TM49 RS07300
gene id: 1486262:TM49_RS07300
uniprot id: A0A0D5LN32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1486262:TM49 RS13375
gene id: 1486262:TM49_RS13375
uniprot id: A0A0D5LQG4
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1486262:TM49 RS03070
gene id: 1486262:TM49_RS03070
uniprot id: A0A0D5LNM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1486262:TM49 RS00595
gene id: 1486262:TM49_RS00595
uniprot id: A0A0D5LL77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1486262:TM49 RS13865
gene id: 1486262:TM49_RS13865
uniprot id: A0A0D5LXM2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS10335
gene id: 1486262:TM49_RS10335
uniprot id: A0A0D5LQE4
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS00770
gene id: 1486262:TM49_RS00770
uniprot id: A0A0D5LMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS12970
gene id: 1486262:TM49_RS12970
uniprot id: A0A0D5LR35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1486262:TM49 RS12470
gene id: 1486262:TM49_RS12470
uniprot id: A0A0D5LSF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1486262:TM49 RS02435
gene id: 1486262:TM49_RS02435
uniprot id: A0A0D5LNA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1486262:TM49 RS08370
gene id: 1486262:TM49_RS08370
uniprot id: A0A0D5LPJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS07325
gene id: 1486262:TM49_RS07325
uniprot id: A0A0D5LMV8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS18905
gene id: 1486262:TM49_RS18905
uniprot id: A0A0D5LV66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS13990
gene id: 1486262:TM49_RS13990
uniprot id: A0A0D5LQP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS01975
gene id: 1486262:TM49_RS01975
uniprot id: A0A0D5LKJ9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1486262:TM49 RS04040
gene id: 1486262:TM49_RS04040
uniprot id: A0A0D5LP06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS19235
gene id: 1486262:TM49_RS19235
uniprot id: A0A0D5LU68
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS17885
gene id: 1486262:TM49_RS17885
uniprot id: A0A0D5LXX9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1486262:TM49 RS19370
gene id: 1486262:TM49_RS19370
uniprot id: A0A0D5LU93
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1486262:TM49 RS03010
gene id: 1486262:TM49_RS03010
uniprot id: A0A0D5LL32
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1486262:TM49 RS02060
gene id: 1486262:TM49_RS02060
uniprot id: A0A0D5LN48
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1486262:TM49 RS08490
gene id: 1486262:TM49_RS08490
uniprot id: A0A0D5LQU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS17795
gene id: 1486262:TM49_RS17795
uniprot id: A0A0D5LSN5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1486262:TM49 RS22190
gene id: 1486262:TM49_RS22190
uniprot id: A0A0D5LVH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS13475
gene id: 1486262:TM49_RS13475
uniprot id: A0A0D5LRS7
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

1486262:TM49 RS00685
gene id: 1486262:TM49_RS00685
uniprot id: A0A0D5LUV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS02475
gene id: 1486262:TM49_RS02475
uniprot id: A0A0D5LLG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS20575
gene id: 1486262:TM49_RS20575
uniprot id: A0A0D5LTJ8
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1486262:TM49 RS09930
gene id: 1486262:TM49_RS09930
uniprot id: A0A0D5LWE1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1486262:TM49 RS08445
gene id: 1486262:TM49_RS08445
uniprot id: A0A0D5LNJ0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1486262:TM49 RS00585
gene id: 1486262:TM49_RS00585
uniprot id: A0A0D5LK56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1486262:TM49 RS10775
gene id: 1486262:TM49_RS10775
uniprot id: A0A0D5LP96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS00150
gene id: 1486262:TM49_RS00150
uniprot id: A0A0D5LMC2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1486262:TM49 RS02740
gene id: 1486262:TM49_RS02740
uniprot id: A0A0D5LNI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS16590
gene id: 1486262:TM49_RS16590
uniprot id: A0A0D5LS88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1486262:TM49 RS02600
gene id: 1486262:TM49_RS02600
uniprot id: A0A0D5LKU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS00285
gene id: 1486262:TM49_RS00285
uniprot id: A0A0D5LME0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS10165
gene id: 1486262:TM49_RS10165
uniprot id: A0A0D5LPA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS16040
gene id: 1486262:TM49_RS16040
uniprot id: A0A0D5LRH8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS09900
gene id: 1486262:TM49_RS09900
uniprot id: A0A0D5LQ80
names: Similarity
messages: Belongs to the sulfatase family.

1486262:TM49 RS21425
gene id: 1486262:TM49_RS21425
uniprot id: A0A0D5LV65
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1486262:TM49 RS05505
gene id: 1486262:TM49_RS05505
uniprot id: A0A0D5LNB9
names: Similarity
messages: Belongs to the GARS family.

1486262:TM49 RS22035
gene id: 1486262:TM49_RS22035
uniprot id: A0A0D5LWG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS19985
gene id: 1486262:TM49_RS19985
uniprot id: A0A0D5LTZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1486262:TM49 RS20615
gene id: 1486262:TM49_RS20615
uniprot id: A0A0D5LU84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS22315
gene id: 1486262:TM49_RS22315
uniprot id: A0A0D5LV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS11835
gene id: 1486262:TM49_RS11835
uniprot id: A0A0D5LS65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

1486262:TM49 RS14625
gene id: 1486262:TM49_RS14625
uniprot id: A0A0D5LRQ5
names: Similarity
messages: Belongs to the fabD family.

1486262:TM49 RS04610
gene id: 1486262:TM49_RS04610
uniprot id: A0A0D5LWZ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS08860
gene id: 1486262:TM49_RS08860
uniprot id: A0A0D5LNG6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1486262:TM49 RS11585
gene id: 1486262:TM49_RS11585
uniprot id: A0A0D5LS22
names: Similarity
messages: Belongs to the TPP enzyme family.

1486262:TM49 RS02305
gene id: 1486262:TM49_RS02305
uniprot id: A0A0D5LLX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

1486262:TM49 RS08320
gene id: 1486262:TM49_RS08320
uniprot id: A0A0D5LX89
names: Similarity
messages: Belongs to the peptidase S33 family.

1486262:TM49 RS01240
gene id: 1486262:TM49_RS01240
uniprot id: A0A0D5LUX3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1486262:TM49 RS09705
gene id: 1486262:TM49_RS09705
uniprot id: A0A0D5LP43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS14505
gene id: 1486262:TM49_RS14505
uniprot id: A0A0D5LW23
names: Similarity
messages: Belongs to the LOG family.

1486262:TM49 RS12505
gene id: 1486262:TM49_RS12505
uniprot id: A0A0D5LQT5
names: Similarity
messages: Belongs to the glutamate synthase family.

1486262:TM49 RS04790
gene id: 1486262:TM49_RS04790
uniprot id: A0A0D5LMH4
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1486262:TM49 RS06825
gene id: 1486262:TM49_RS06825
uniprot id: A0A0D5LMQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1486262:TM49 RS05630
gene id: 1486262:TM49_RS05630
uniprot id: A0A0D5LMW1
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1486262:TM49 RS20770
gene id: 1486262:TM49_RS20770
uniprot id: A0A0D5LTM9
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1486262:TM49 RS06145
gene id: 1486262:TM49_RS06145
uniprot id: A0A0D5LN73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS04935
gene id: 1486262:TM49_RS04935
uniprot id: A0A0D5LVG6
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1486262:TM49 RS18645
gene id: 1486262:TM49_RS18645
uniprot id: A0A0D5LTD4
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS03280
gene id: 1486262:TM49_RS03280
uniprot id: A0A0D5LLX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS17115
gene id: 1486262:TM49_RS17115
uniprot id: A0A0D5LTC9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS15925
gene id: 1486262:TM49_RS15925
uniprot id: A0A0D5LRG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS19410
gene id: 1486262:TM49_RS19410
uniprot id: A0A0D5LTC1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1486262:TM49 RS03525
gene id: 1486262:TM49_RS03525
uniprot id: A0A0D5LNT6
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1486262:TM49 RS03305
gene id: 1486262:TM49_RS03305
uniprot id: A0A0D5LL74
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1486262:TM49 RS02570
gene id: 1486262:TM49_RS02570
uniprot id: A0A0D5LND1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS14155
gene id: 1486262:TM49_RS14155
uniprot id: A0A0D5LS02
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS04230
gene id: 1486262:TM49_RS04230
uniprot id: A0A0D5LLL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1486262:TM49 RS03630
gene id: 1486262:TM49_RS03630
uniprot id: A0A0D5LMI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS06775
gene id: 1486262:TM49_RS06775
uniprot id: A0A0D5LNX9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS18110
gene id: 1486262:TM49_RS18110
uniprot id: A0A0D5LSU0
names: Similarity
messages: Belongs to the HesB/IscA family.

1486262:TM49 RS00405
gene id: 1486262:TM49_RS00405
uniprot id: A0A0D5LMF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1486262:TM49 RS19190
gene id: 1486262:TM49_RS19190
uniprot id: A0A0D5LY36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS05450
gene id: 1486262:TM49_RS05450
uniprot id: A0A0D5LMT5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1486262:TM49 RS01405
gene id: 1486262:TM49_RS01405
uniprot id: A0A0D5LMV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

1486262:TM49 RS15780
gene id: 1486262:TM49_RS15780
uniprot id: A0A0D5LS51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS18285
gene id: 1486262:TM49_RS18285
uniprot id: A0A0D5LSW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1486262:TM49 RS08705
gene id: 1486262:TM49_RS08705
uniprot id: A0A0D5LPQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1486262:TM49 RS01925
gene id: 1486262:TM49_RS01925
uniprot id: A0A0D5LN29
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS14475
gene id: 1486262:TM49_RS14475
uniprot id: A0A0D5LR64
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1486262:TM49 RS07030
gene id: 1486262:TM49_RS07030
uniprot id: A0A0D5LMS6
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS14945
gene id: 1486262:TM49_RS14945
uniprot id: A0A0D5LR27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1486262:TM49 RS14515
gene id: 1486262:TM49_RS14515
uniprot id: A0A0D5LWQ3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1486262:TM49 RS03150
gene id: 1486262:TM49_RS03150
uniprot id: A0A0D5LNP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS19805
gene id: 1486262:TM49_RS19805
uniprot id: A0A0D5LUH6
names: PTM
messages: Binds 1 heme group per subunit.

1486262:TM49 RS02145
gene id: 1486262:TM49_RS02145
uniprot id: A0A0D5LN61
names: Similarity
messages: Belongs to the allantoicase family.

1486262:TM49 RS15725
gene id: 1486262:TM49_RS15725
uniprot id: A0A0D5LRM1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS08815
gene id: 1486262:TM49_RS08815
uniprot id: A0A0D5LPR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS01945
gene id: 1486262:TM49_RS01945
uniprot id: A0A0D5LKN4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1486262:TM49 RS16795
gene id: 1486262:TM49_RS16795
uniprot id: A0A0D5LT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1486262:TM49 RS05105
gene id: 1486262:TM49_RS05105
uniprot id: A0A0D5LM26
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1486262:TM49 RS04120
gene id: 1486262:TM49_RS04120
uniprot id: A0A0D5LV79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1486262:TM49 RS17670
gene id: 1486262:TM49_RS17670
uniprot id: A0A0D5LSL8
names: Similarity
messages: Belongs to the UPF0758 family.

1486262:TM49 RS02915
gene id: 1486262:TM49_RS02915
uniprot id: A0A0D5LL23
names: Similarity
messages: Belongs to the DapA family.

1486262:TM49 RS12985
gene id: 1486262:TM49_RS12985
uniprot id: A0A0D5LSQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1486262:TM49 RS01475
gene id: 1486262:TM49_RS01475
uniprot id: A0A0D5LLK9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1486262:TM49 RS17005
gene id: 1486262:TM49_RS17005
uniprot id: A0A0D5LUG4
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1486262:TM49 RS11150
gene id: 1486262:TM49_RS11150
uniprot id: A0A0D5LPG0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS09765
gene id: 1486262:TM49_RS09765
uniprot id: A0A0D5LUZ9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1486262:TM49 RS19585
gene id: 1486262:TM49_RS19585
uniprot id: A0A0D5LWL4
names: Similarity
messages: Belongs to the peptidase S49 family.

1486262:TM49 RS18365
gene id: 1486262:TM49_RS18365
uniprot id: A0A0D5LSX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1486262:TM49 RS14795
gene id: 1486262:TM49_RS14795
uniprot id: A0A0D5LRS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1486262:TM49 RS08020
gene id: 1486262:TM49_RS08020
uniprot id: A0A0D5LNV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1486262:TM49 RS15055
gene id: 1486262:TM49_RS15055
uniprot id: A0A0D5LRE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1486262:TM49 RS19920
gene id: 1486262:TM49_RS19920
uniprot id: A0A0D5LUJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1486262:TM49 RS20810
gene id: 1486262:TM49_RS20810
uniprot id: A0A0D5LUB8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS14540
gene id: 1486262:TM49_RS14540
uniprot id: A0A0D5LR72
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS14000
gene id: 1486262:TM49_RS14000
uniprot id: A0A0D5LQZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS10580
gene id: 1486262:TM49_RS10580
uniprot id: A0A0D5LRP0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1486262:TM49 RS22150
gene id: 1486262:TM49_RS22150
uniprot id: A0A0D5LUM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS14140
gene id: 1486262:TM49_RS14140
uniprot id: A0A0D5LRJ1
names: Similarity
messages: Belongs to the YkuD family.

1486262:TM49 RS03140
gene id: 1486262:TM49_RS03140
uniprot id: A0A0D5LL91
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS20345
gene id: 1486262:TM49_RS20345
uniprot id: A0A0D5LTG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1486262:TM49 RS18465
gene id: 1486262:TM49_RS18465
uniprot id: A0A0D5LTA2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1486262:TM49 RS21150
gene id: 1486262:TM49_RS21150
uniprot id: A0A0D5LW44
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS12765
gene id: 1486262:TM49_RS12765
uniprot id: A0A0D5LQC4
names: Similarity
messages: Belongs to the UPF0335 family.

1486262:TM49 RS00060
gene id: 1486262:TM49_RS00060
uniprot id: A0A0D5LKZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1486262:TM49 RS20910
gene id: 1486262:TM49_RS20910
uniprot id: A0A0D5LU36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS08800
gene id: 1486262:TM49_RS08800
uniprot id: A0A0D5LNG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1486262:TM49 RS07995
gene id: 1486262:TM49_RS07995
uniprot id: A0A0D5LNC1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Multidrug efflux pump.

1486262:TM49 RS19460
gene id: 1486262:TM49_RS19460
uniprot id: A0A0D5LTR1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1486262:TM49 RS01395
gene id: 1486262:TM49_RS01395
uniprot id: A0A0D5LKG3
names: Similarity
messages: Belongs to the UPF0145 family.

1486262:TM49 RS09800
gene id: 1486262:TM49_RS09800
uniprot id: A0A0D5LPQ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1486262:TM49 RS18805
gene id: 1486262:TM49_RS18805
uniprot id: A0A0D5LT37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1486262:TM49 RS12245
gene id: 1486262:TM49_RS12245
uniprot id: A0A0D5LSB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1486262:TM49 RS22065
gene id: 1486262:TM49_RS22065
uniprot id: A0A0D5LVF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS10550
gene id: 1486262:TM49_RS10550
uniprot id: A0A0D5LP57
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS14935
gene id: 1486262:TM49_RS14935
uniprot id: A0A0D5LSC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1486262:TM49 RS16620
gene id: 1486262:TM49_RS16620
uniprot id: A0A0D5LS92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

1486262:TM49 RS14740
gene id: 1486262:TM49_RS14740
uniprot id: A0A0D5LSA0
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1486262:TM49 RS21265
gene id: 1486262:TM49_RS21265
uniprot id: A0A0D5LPN4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1486262:TM49 RS16545
gene id: 1486262:TM49_RS16545
uniprot id: A0A0D5LUA8
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS13545
gene id: 1486262:TM49_RS13545
uniprot id: A0A0D5LSY7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1486262:TM49 RS04955
gene id: 1486262:TM49_RS04955
uniprot id: A0A0D5LLV8
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1486262:TM49 RS19355
gene id: 1486262:TM49_RS19355
uniprot id: A0A0D5LSZ9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1486262:TM49 RS03385
gene id: 1486262:TM49_RS03385
uniprot id: A0A0D5LLY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS06065
gene id: 1486262:TM49_RS06065
uniprot id: A0A0D5LN56
names: Function
messages: Acts on leucine, isoleucine and valine.

1486262:TM49 RS07410
gene id: 1486262:TM49_RS07410
uniprot id: A0A0D5LQE1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1486262:TM49 RS11470
gene id: 1486262:TM49_RS11470
uniprot id: A0A0D5LPU8
names: Function
names: Similarity
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

1486262:TM49 RS14790
gene id: 1486262:TM49_RS14790
uniprot id: A0A0D5LR07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS12315
gene id: 1486262:TM49_RS12315
uniprot id: A0A0D5LQQ7
names: Similarity
messages: Belongs to the GcvT family.

1486262:TM49 RS05230
gene id: 1486262:TM49_RS05230
uniprot id: A0A0D5LLZ5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1486262:TM49 RS18255
gene id: 1486262:TM49_RS18255
uniprot id: A0A0D5LTT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS08745
gene id: 1486262:TM49_RS08745
uniprot id: A0A0D5LNF2
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS22165
gene id: 1486262:TM49_RS22165
uniprot id: A0A0D5LWI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS21660
gene id: 1486262:TM49_RS21660
uniprot id: A0A0D5LUN7
names: Similarity
messages: Belongs to the YciI family.

1486262:TM49 RS04940
gene id: 1486262:TM49_RS04940
uniprot id: A0A0D5LVA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1486262:TM49 RS04585
gene id: 1486262:TM49_RS04585
uniprot id: A0A0D5LME5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS05365
gene id: 1486262:TM49_RS05365
uniprot id: A0A0D5LM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS18815
gene id: 1486262:TM49_RS18815
uniprot id: A0A0D5LV55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS21560
gene id: 1486262:TM49_RS21560
uniprot id: A0A0D5LTX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1486262:TM49 RS07875
gene id: 1486262:TM49_RS07875
uniprot id: A0A0D5LVJ8
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS03700
gene id: 1486262:TM49_RS03700
uniprot id: A0A0D5LM29
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS05325
gene id: 1486262:TM49_RS05325
uniprot id: A0A0D5LPI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS20705
gene id: 1486262:TM49_RS20705
uniprot id: A0A0D5LVY1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS12845
gene id: 1486262:TM49_RS12845
uniprot id: A0A0D5LQG9
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1486262:TM49 RS16715
gene id: 1486262:TM49_RS16715
uniprot id: A0A0D5LSA8
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS02155
gene id: 1486262:TM49_RS02155
uniprot id: A0A0D5LLA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1486262:TM49 RS15795
gene id: 1486262:TM49_RS15795
uniprot id: A0A0D5LSN9
names: Similarity
messages: Belongs to the sulfatase family.

1486262:TM49 RS10805
gene id: 1486262:TM49_RS10805
uniprot id: A0A0D5LQ40
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1486262:TM49 RS13380
gene id: 1486262:TM49_RS13380
uniprot id: A0A0D5LR95
names: Similarity
messages: Belongs to the BolA/IbaG family.

1486262:TM49 RS13890
gene id: 1486262:TM49_RS13890
uniprot id: A0A0D5LT31
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS02985
gene id: 1486262:TM49_RS02985
uniprot id: A0A0D5LLS5
names: Similarity
messages: Belongs to the peptidase S58 family.

1486262:TM49 RS02200
gene id: 1486262:TM49_RS02200
uniprot id: A0A0D5LKR8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1486262:TM49 RS07525
gene id: 1486262:TM49_RS07525
uniprot id: A0A0D5LNQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1486262:TM49 RS16380
gene id: 1486262:TM49_RS16380
uniprot id: A0A0D5LSI9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1486262:TM49 RS00315
gene id: 1486262:TM49_RS00315
uniprot id: A0A0D5LWM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS21420
gene id: 1486262:TM49_RS21420
uniprot id: A0A0D5LUB2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1486262:TM49 RS08850
gene id: 1486262:TM49_RS08850
uniprot id: A0A0D5LPS4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1486262:TM49 RS03265
gene id: 1486262:TM49_RS03265
uniprot id: A0A0D5LME1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS06550
gene id: 1486262:TM49_RS06550
uniprot id: A0A0D5LNU6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1486262:TM49 RS05545
gene id: 1486262:TM49_RS05545
uniprot id: A0A0D5LM45
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1486262:TM49 RS18215
gene id: 1486262:TM49_RS18215
uniprot id: A0A0D5LSV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1486262:TM49 RS12810
gene id: 1486262:TM49_RS12810
uniprot id: A0A0D5LQ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1486262:TM49 RS11650
gene id: 1486262:TM49_RS11650
uniprot id: A0A0D5LS32
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

1486262:TM49 RS02790
gene id: 1486262:TM49_RS02790
uniprot id: A0A0D5LM85
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS18385
gene id: 1486262:TM49_RS18385
uniprot id: A0A0D5LSL4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1486262:TM49 RS08290
gene id: 1486262:TM49_RS08290
uniprot id: A0A0D5LNG8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS13165
gene id: 1486262:TM49_RS13165
uniprot id: A0A0D5LR65
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1486262:TM49 RS06540
gene id: 1486262:TM49_RS06540
uniprot id: A0A0D5LNC8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1486262:TM49 RS00135
gene id: 1486262:TM49_RS00135
uniprot id: A0A0D5LJY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS08115
gene id: 1486262:TM49_RS08115
uniprot id: A0A0D5LNX3
names: Similarity
messages: Belongs to the peptidase S9A family.

1486262:TM49 RS05535
gene id: 1486262:TM49_RS05535
uniprot id: A0A0D5LNC4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1486262:TM49 RS12170
gene id: 1486262:TM49_RS12170
uniprot id: A0A0D5LSA9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS14555
gene id: 1486262:TM49_RS14555
uniprot id: A0A0D5LXQ0
names: Caution
names: Function
names: Similarity
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS11730
gene id: 1486262:TM49_RS11730
uniprot id: A0A0D5LQG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS15275
gene id: 1486262:TM49_RS15275
uniprot id: A0A0D5LR77
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1486262:TM49 RS18000
gene id: 1486262:TM49_RS18000
uniprot id: A0A0D5LTP5
names: Similarity
messages: Belongs to the XFP family.

1486262:TM49 RS10610
gene id: 1486262:TM49_RS10610
uniprot id: A0A0D5LP67
names: Similarity
messages: Belongs to the AHA1 family.

1486262:TM49 RS19965
gene id: 1486262:TM49_RS19965
uniprot id: A0A0D5LTP6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1486262:TM49 RS06005
gene id: 1486262:TM49_RS06005
uniprot id: A0A0D5LN40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1486262:TM49 RS17155
gene id: 1486262:TM49_RS17155
uniprot id: A0A0D5LTD2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1486262:TM49 RS13040
gene id: 1486262:TM49_RS13040
uniprot id: A0A0D5LQK3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1486262:TM49 RS13520
gene id: 1486262:TM49_RS13520
uniprot id: A0A0D5LQI7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS06900
gene id: 1486262:TM49_RS06900
uniprot id: A0A0D5LNH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS05235
gene id: 1486262:TM49_RS05235
uniprot id: A0A0D5LMP2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS03045
gene id: 1486262:TM49_RS03045
uniprot id: A0A0D5LNM5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1486262:TM49 RS19790
gene id: 1486262:TM49_RS19790
uniprot id: A0A0D5LT92
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1486262:TM49 RS19560
gene id: 1486262:TM49_RS19560
uniprot id: A0A0D5LUE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1486262:TM49 RS21725
gene id: 1486262:TM49_RS21725
uniprot id: A0A0D5LU00
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1486262:TM49 RS03945
gene id: 1486262:TM49_RS03945
uniprot id: A0A0D5LMN0
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1486262:TM49 RS11100
gene id: 1486262:TM49_RS11100
uniprot id: A0A0D5LPP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1486262:TM49 RS19700
gene id: 1486262:TM49_RS19700
uniprot id: A0A0D5LTK2
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1486262:TM49 RS10130
gene id: 1486262:TM49_RS10130
uniprot id: A0A0D5LPA4
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1486262:TM49 RS04260
gene id: 1486262:TM49_RS04260
uniprot id: A0A0D5LMT1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS12685
gene id: 1486262:TM49_RS12685
uniprot id: A0A0D5LSH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS16015
gene id: 1486262:TM49_RS16015
uniprot id: A0A0D5LS99
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1486262:TM49 RS00935
gene id: 1486262:TM49_RS00935
uniprot id: A0A0D5LK47
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS05035
gene id: 1486262:TM49_RS05035
uniprot id: A0A0D5LN46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1486262:TM49 RS09325
gene id: 1486262:TM49_RS09325
uniprot id: A0A0D5LPG9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS05050
gene id: 1486262:TM49_RS05050
uniprot id: A0A0D5LPF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1486262:TM49 RS10755
gene id: 1486262:TM49_RS10755
uniprot id: A0A0D5LQ30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1486262:TM49 RS11245
gene id: 1486262:TM49_RS11245
uniprot id: A0A0D5LPH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1486262:TM49 RS13055
gene id: 1486262:TM49_RS13055
uniprot id: A0A0D5LSR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS21750
gene id: 1486262:TM49_RS21750
uniprot id: A0A0D5LU02
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1486262:TM49 RS18025
gene id: 1486262:TM49_RS18025
uniprot id: A0A0D5LTQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1486262:TM49 RS21675
gene id: 1486262:TM49_RS21675
uniprot id: A0A0D5LWX2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1486262:TM49 RS09025
gene id: 1486262:TM49_RS09025
uniprot id: A0A0D5LPC6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS03595
gene id: 1486262:TM49_RS03595
uniprot id: A0A0D5LMI4
names: Similarity
messages: Belongs to the group II decarboxylase family.

1486262:TM49 RS11840
gene id: 1486262:TM49_RS11840
uniprot id: A0A0D5LPQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS14270
gene id: 1486262:TM49_RS14270
uniprot id: A0A0D5LVA2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS06475
gene id: 1486262:TM49_RS06475
uniprot id: A0A0D5LMK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1486262:TM49 RS10185
gene id: 1486262:TM49_RS10185
uniprot id: A0A0D5LPV5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1486262:TM49 RS11880
gene id: 1486262:TM49_RS11880
uniprot id: A0A0D5LQ06
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS14965
gene id: 1486262:TM49_RS14965
uniprot id: A0A0D5LSC8
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1486262:TM49 RS07685
gene id: 1486262:TM49_RS07685
uniprot id: A0A0D5LQG7
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1486262:TM49 RS09030
gene id: 1486262:TM49_RS09030
uniprot id: A0A0D5LNS4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1486262:TM49 RS14490
gene id: 1486262:TM49_RS14490
uniprot id: A0A0D5LQW4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1486262:TM49 RS19870
gene id: 1486262:TM49_RS19870
uniprot id: A0A0D5LWT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1486262:TM49 RS02805
gene id: 1486262:TM49_RS02805
uniprot id: A0A0D5LLQ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1486262:TM49 RS12890
gene id: 1486262:TM49_RS12890
uniprot id: A0A0D5LRJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1486262:TM49 RS11875
gene id: 1486262:TM49_RS11875
uniprot id: A0A0D5LQJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

1486262:TM49 RS10810
gene id: 1486262:TM49_RS10810
uniprot id: A0A0D5LPK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1486262:TM49 RS00440
gene id: 1486262:TM49_RS00440
uniprot id: A0A0D5LKM6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS11870
gene id: 1486262:TM49_RS11870
uniprot id: A0A0D5LPR4
names: Similarity
messages: Belongs to the BolA/IbaG family.

1486262:TM49 RS10925
gene id: 1486262:TM49_RS10925
uniprot id: A0A0D5LPL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1486262:TM49 RS06610
gene id: 1486262:TM49_RS06610
uniprot id: A0A0D5LNV5
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1486262:TM49 RS09920
gene id: 1486262:TM49_RS09920
uniprot id: A0A0D5LPS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS02705
gene id: 1486262:TM49_RS02705
uniprot id: A0A0D5LKZ6
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1486262:TM49 RS02300
gene id: 1486262:TM49_RS02300
uniprot id: A0A0D5LKT1
names: Similarity
messages: Belongs to the TPP enzyme family.

1486262:TM49 RS11910
gene id: 1486262:TM49_RS11910
uniprot id: A0A0D5LR31
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1486262:TM49 RS12770
gene id: 1486262:TM49_RS12770
uniprot id: A0A0D5LRE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS07405
gene id: 1486262:TM49_RS07405
uniprot id: A0A0D5LP61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS02880
gene id: 1486262:TM49_RS02880
uniprot id: A0A0D5LLR6
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.

1486262:TM49 RS19535
gene id: 1486262:TM49_RS19535
uniprot id: A0A0D5LT56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS01440
gene id: 1486262:TM49_RS01440
uniprot id: A0A0D5LMV9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1486262:TM49 RS00465
gene id: 1486262:TM49_RS00465
uniprot id: A0A0D5LKN1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1486262:TM49 RS03420
gene id: 1486262:TM49_RS03420
uniprot id: A0A0D5LMG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS17025
gene id: 1486262:TM49_RS17025
uniprot id: A0A0D5LSE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS15720
gene id: 1486262:TM49_RS15720
uniprot id: A0A0D5LS42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS11500
gene id: 1486262:TM49_RS11500
uniprot id: A0A0D5LQD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1486262:TM49 RS05390
gene id: 1486262:TM49_RS05390
uniprot id: A0A0D5LUP1
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

1486262:TM49 RS06890
gene id: 1486262:TM49_RS06890
uniprot id: A0A0D5LW57
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1486262:TM49 RS20620
gene id: 1486262:TM49_RS20620
uniprot id: A0A0D5LTZ7
names: Similarity
messages: Belongs to the thioester dehydratase family. FabA subfamily.

1486262:TM49 RS10120
gene id: 1486262:TM49_RS10120
uniprot id: A0A0D5LNZ4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1486262:TM49 RS17720
gene id: 1486262:TM49_RS17720
uniprot id: A0A0D5LSB6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS11815
gene id: 1486262:TM49_RS11815
uniprot id: A0A0D5LPQ2
names: Similarity
messages: Belongs to the pirin family.

1486262:TM49 RS06495
gene id: 1486262:TM49_RS06495
uniprot id: A0A0D5LVF5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS13435
gene id: 1486262:TM49_RS13435
uniprot id: A0A0D5LQH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1486262:TM49 RS21680
gene id: 1486262:TM49_RS21680
uniprot id: A0A0D5LWA1
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1486262:TM49 RS06965
gene id: 1486262:TM49_RS06965
uniprot id: A0A0D5LQ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1486262:TM49 RS05550
gene id: 1486262:TM49_RS05550
uniprot id: A0A0D5LMV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1486262:TM49 RS10405
gene id: 1486262:TM49_RS10405
uniprot id: A0A0D5LRM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1486262:TM49 RS18260
gene id: 1486262:TM49_RS18260
uniprot id: A0A0D5LUX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1486262:TM49 RS10665
gene id: 1486262:TM49_RS10665
uniprot id: A0A0D5LP75
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1486262:TM49 RS11390
gene id: 1486262:TM49_RS11390
uniprot id: A0A0D5LQB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1486262:TM49 RS05400
gene id: 1486262:TM49_RS05400
uniprot id: A0A0D5LM69
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1486262:TM49 RS06795
gene id: 1486262:TM49_RS06795
uniprot id: A0A0D5LNG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS02125
gene id: 1486262:TM49_RS02125
uniprot id: A0A0D5LVT0
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1486262:TM49 RS14380
gene id: 1486262:TM49_RS14380
uniprot id: A0A0D5LQU1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS09700
gene id: 1486262:TM49_RS09700
uniprot id: A0A0D5LPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS09585
gene id: 1486262:TM49_RS09585
uniprot id: A0A0D5LVU3
names: Similarity
messages: Belongs to the DapA family.

1486262:TM49 RS17955
gene id: 1486262:TM49_RS17955
uniprot id: A0A0D5LT33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS10410
gene id: 1486262:TM49_RS10410
uniprot id: A0A0D5LP41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1486262:TM49 RS16510
gene id: 1486262:TM49_RS16510
uniprot id: A0A0D5LT38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1486262:TM49 RS12095
gene id: 1486262:TM49_RS12095
uniprot id: A0A0D5LQ32
names: Subcellular Location Annotation
messages: Cytoplasm

1486262:TM49 RS20890
gene id: 1486262:TM49_RS20890
uniprot id: A0A0D5LTP1
names: Similarity
messages: Belongs to the UPF0102 family.

1486262:TM49 RS16080
gene id: 1486262:TM49_RS16080
uniprot id: A0A0D5LRY2
names: Similarity
messages: Belongs to the PhzF family.

1486262:TM49 RS16655
gene id: 1486262:TM49_RS16655
uniprot id: A0A0D5LT66
names: Similarity
messages: Belongs to the TrpC family.

1486262:TM49 RS01175
gene id: 1486262:TM49_RS01175
uniprot id: A0A0D5LK81
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1486262:TM49 RS11090
gene id: 1486262:TM49_RS11090
uniprot id: A0A0D5LPE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1486262:TM49 RS17685
gene id: 1486262:TM49_RS17685
uniprot id: A0A0D5LWX4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1486262:TM49 RS07145
gene id: 1486262:TM49_RS07145
uniprot id: A0A0D5LMT7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS02065
gene id: 1486262:TM49_RS02065
uniprot id: A0A0D5LKL5
names: Similarity
messages: Belongs to the YfgM family.

1486262:TM49 RS03270
gene id: 1486262:TM49_RS03270
uniprot id: A0A0D5LNQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS02370
gene id: 1486262:TM49_RS02370
uniprot id: A0A0D5LKU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1486262:TM49 RS19970
gene id: 1486262:TM49_RS19970
uniprot id: A0A0D5LUK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1486262:TM49 RS10520
gene id: 1486262:TM49_RS10520
uniprot id: A0A0D5LP52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS01045
gene id: 1486262:TM49_RS01045
uniprot id: A0A0D5LKA5
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS06460
gene id: 1486262:TM49_RS06460
uniprot id: A0A0D5LMQ8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1486262:TM49 RS19350
gene id: 1486262:TM49_RS19350
uniprot id: A0A0D5LVC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1486262:TM49 RS21815
gene id: 1486262:TM49_RS21815
uniprot id: A0A0D5LUR5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS18685
gene id: 1486262:TM49_RS18685
uniprot id: A0A0D5LWF7
names: Similarity
messages: Belongs to the SufE family.

1486262:TM49 RS16325
gene id: 1486262:TM49_RS16325
uniprot id: A0A0D5LRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecG subfamily.
messages: Cell inner membrane
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1486262:TM49 RS08640
gene id: 1486262:TM49_RS08640
uniprot id: A0A0D5LP55
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1486262:TM49 RS06830
gene id: 1486262:TM49_RS06830
uniprot id: A0A0D5LNH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS09630
gene id: 1486262:TM49_RS09630
uniprot id: A0A0D5LNS7
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family.

1486262:TM49 RS08060
gene id: 1486262:TM49_RS08060
uniprot id: A0A0D5LPF1
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1486262:TM49 RS02485
gene id: 1486262:TM49_RS02485
uniprot id: A0A0D5LM08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS06615
gene id: 1486262:TM49_RS06615
uniprot id: A0A0D5LQ43
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS09675
gene id: 1486262:TM49_RS09675
uniprot id: A0A0D5LP38
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1486262:TM49 RS08075
gene id: 1486262:TM49_RS08075
uniprot id: A0A0D5LN44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS12065
gene id: 1486262:TM49_RS12065
uniprot id: A0A0D5LR51
names: Similarity
messages: Belongs to the GST superfamily.

1486262:TM49 RS22115
gene id: 1486262:TM49_RS22115
uniprot id: A0A0D5LUY7
names: Similarity
messages: Belongs to the proline racemase family.

1486262:TM49 RS06500
gene id: 1486262:TM49_RS06500
uniprot id: A0A0D5LQ24
names: Similarity
messages: Belongs to the peptidase C56 family.

1486262:TM49 RS20565
gene id: 1486262:TM49_RS20565
uniprot id: A0A0D5LWU5
names: Similarity
messages: Belongs to the peptidase M17 family.

1486262:TM49 RS03975
gene id: 1486262:TM49_RS03975
uniprot id: A0A0D5LMN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS10365
gene id: 1486262:TM49_RS10365
uniprot id: A0A0D5LPX9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1486262:TM49 RS21940
gene id: 1486262:TM49_RS21940
uniprot id: A0A0D5LUI8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS07200
gene id: 1486262:TM49_RS07200
uniprot id: A0A0D5LN20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1486262:TM49 RS00955
gene id: 1486262:TM49_RS00955
uniprot id: A0A0D5LMM4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS01605
gene id: 1486262:TM49_RS01605
uniprot id: A0A0D5LKJ3
names: Similarity
messages: Belongs to the peptidase S14 family.

1486262:TM49 RS01345
gene id: 1486262:TM49_RS01345
uniprot id: A0A0D5LKB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS08890
gene id: 1486262:TM49_RS08890
uniprot id: A0A0D5LPA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1486262:TM49 RS10620
gene id: 1486262:TM49_RS10620
uniprot id: A0A0D5LPH3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS12280
gene id: 1486262:TM49_RS12280
uniprot id: A0A0D5LSC2
names: Similarity
messages: Belongs to the glutamate synthase family.

1486262:TM49 RS00695
gene id: 1486262:TM49_RS00695
uniprot id: A0A0D5LK67
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1486262:TM49 RS18245
gene id: 1486262:TM49_RS18245
uniprot id: A0A0D5LT65
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS13130
gene id: 1486262:TM49_RS13130
uniprot id: A0A0D5LQC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS21865
gene id: 1486262:TM49_RS21865
uniprot id: A0A0D5LW14
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1486262:TM49 RS05315
gene id: 1486262:TM49_RS05315
uniprot id: A0A0D5LM56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS20325
gene id: 1486262:TM49_RS20325
uniprot id: A0A0D5LTU7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1486262:TM49 RS14645
gene id: 1486262:TM49_RS14645
uniprot id: A0A0D5LTD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1486262:TM49 RS11810
gene id: 1486262:TM49_RS11810
uniprot id: A0A0D5LS61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1486262:TM49 RS16300
gene id: 1486262:TM49_RS16300
uniprot id: A0A0D5LRT8
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS13110
gene id: 1486262:TM49_RS13110
uniprot id: A0A0D5LQL4
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1486262:TM49 RS22170
gene id: 1486262:TM49_RS22170
uniprot id: A0A0D5LU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS02735
gene id: 1486262:TM49_RS02735
uniprot id: A0A0D5LM70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS20930
gene id: 1486262:TM49_RS20930
uniprot id: A0A0D5LUC9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1486262:TM49 RS17045
gene id: 1486262:TM49_RS17045
uniprot id: A0A0D5LSS5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS09130
gene id: 1486262:TM49_RS09130
uniprot id: A0A0D5LNJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1486262:TM49 RS06410
gene id: 1486262:TM49_RS06410
uniprot id: A0A0D5LVK8
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1486262:TM49 RS05980
gene id: 1486262:TM49_RS05980
uniprot id: A0A0D5LNI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1486262:TM49 RS01115
gene id: 1486262:TM49_RS01115
uniprot id: A0A0D5LMQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1486262:TM49 RS15580
gene id: 1486262:TM49_RS15580
uniprot id: A0A0D5LRA8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-101 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1486262:TM49 RS06625
gene id: 1486262:TM49_RS06625
uniprot id: A0A0D5LNE3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS14010
gene id: 1486262:TM49_RS14010
uniprot id: A0A0D5LRY6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS02400
gene id: 1486262:TM49_RS02400
uniprot id: A0A0D5LKU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS16830
gene id: 1486262:TM49_RS16830
uniprot id: A0A0D5LUE2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1486262:TM49 RS18170
gene id: 1486262:TM49_RS18170
uniprot id: A0A0D5LXY6
names: Similarity
messages: Belongs to the SCO1/2 family.

1486262:TM49 RS21030
gene id: 1486262:TM49_RS21030
uniprot id: A0A0D5LY90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS05785
gene id: 1486262:TM49_RS05785
uniprot id: A0A0D5LPQ6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1486262:TM49 RS20015
gene id: 1486262:TM49_RS20015
uniprot id: A0A0D5LX73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1486262:TM49 RS13320
gene id: 1486262:TM49_RS13320
uniprot id: A0A0D5LSV3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1486262:TM49 RS02230
gene id: 1486262:TM49_RS02230
uniprot id: A0A0D5LLB9
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1486262:TM49 RS04300
gene id: 1486262:TM49_RS04300
uniprot id: A0A0D5LLL8
names: Similarity
messages: Belongs to the SCO1/2 family.

1486262:TM49 RS20255
gene id: 1486262:TM49_RS20255
uniprot id: A0A0D5LY76
names: Function
messages: Acts on leucine, isoleucine and valine.

1486262:TM49 RS19630
gene id: 1486262:TM49_RS19630
uniprot id: A0A0D5LUE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1486262:TM49 RS09230
gene id: 1486262:TM49_RS09230
uniprot id: A0A0D5LNK5
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS15295
gene id: 1486262:TM49_RS15295
uniprot id: A0A0D5LW47
names: Similarity
messages: Belongs to the DinB family.

1486262:TM49 RS15480
gene id: 1486262:TM49_RS15480
uniprot id: A0A0D5LSK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1486262:TM49 RS13280
gene id: 1486262:TM49_RS13280
uniprot id: A0A0D5LRP6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS21210
gene id: 1486262:TM49_RS21210
uniprot id: A0A0D5LV27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

1486262:TM49 RS21655
gene id: 1486262:TM49_RS21655
uniprot id: A0A0D5LTZ2
names: Subcellular Location Annotation
messages: Nucleus

1486262:TM49 RS15540
gene id: 1486262:TM49_RS15540
uniprot id: A0A0D5LTR0
names: Similarity
messages: Belongs to the HesB/IscA family.

1486262:TM49 RS05300
gene id: 1486262:TM49_RS05300
uniprot id: A0A0D5LPI5
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

1486262:TM49 RS14825
gene id: 1486262:TM49_RS14825
uniprot id: A0A0D5LXQ7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1486262:TM49 RS05070
gene id: 1486262:TM49_RS05070
uniprot id: A0A0D5LW07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1486262:TM49 RS00860
gene id: 1486262:TM49_RS00860
uniprot id: A0A0D5LML3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS15330
gene id: 1486262:TM49_RS15330
uniprot id: A0A0D5LTN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1486262:TM49 RS06455
gene id: 1486262:TM49_RS06455
uniprot id: A0A0D5LNB3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS14440
gene id: 1486262:TM49_RS14440
uniprot id: A0A0D5LR59
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1486262:TM49 RS16735
gene id: 1486262:TM49_RS16735
uniprot id: A0A0D5LSN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1486262:TM49 RS14655
gene id: 1486262:TM49_RS14655
uniprot id: A0A0D5LRQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1486262:TM49 RS08265
gene id: 1486262:TM49_RS08265
uniprot id: A0A0D5LPI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1486262:TM49 RS13030
gene id: 1486262:TM49_RS13030
uniprot id: A0A0D5LQB6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1486262:TM49 RS02990
gene id: 1486262:TM49_RS02990
uniprot id: A0A0D5LL66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1486262:TM49 RS14835
gene id: 1486262:TM49_RS14835
uniprot id: A0A0D5LVB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1486262:TM49 RS15840
gene id: 1486262:TM49_RS15840
uniprot id: A0A0D5LS66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS19415
gene id: 1486262:TM49_RS19415
uniprot id: A0A0D5LU97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1486262:TM49 RS11885
gene id: 1486262:TM49_RS11885
uniprot id: A0A0D5LR26
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1486262:TM49 RS00735
gene id: 1486262:TM49_RS00735
uniprot id: A0A0D5LMJ9
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.

1486262:TM49 RS04010
gene id: 1486262:TM49_RS04010
uniprot id: A0A0D5LMP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS02660
gene id: 1486262:TM49_RS02660
uniprot id: A0A0D5LNE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS15825
gene id: 1486262:TM49_RS15825
uniprot id: A0A0D5LSP4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS07000
gene id: 1486262:TM49_RS07000
uniprot id: A0A0D5LNJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose mutarotase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the anomeric conversion of L-rhamnose.

1486262:TM49 RS17975
gene id: 1486262:TM49_RS17975
uniprot id: A0A0D5LWY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS07455
gene id: 1486262:TM49_RS07455
uniprot id: A0A0D5LW76
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1486262:TM49 RS15620
gene id: 1486262:TM49_RS15620
uniprot id: A0A0D5LWD5
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1486262:TM49 RS21455
gene id: 1486262:TM49_RS21455
uniprot id: A0A0D5LUB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1486262:TM49 RS15985
gene id: 1486262:TM49_RS15985
uniprot id: A0A0D5LRG8
names: Similarity
messages: Belongs to the peptidase C59 family.

1486262:TM49 RS04520
gene id: 1486262:TM49_RS04520
uniprot id: A0A0D5LLP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS08965
gene id: 1486262:TM49_RS08965
uniprot id: A0A0D5LR18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1486262:TM49 RS12830
gene id: 1486262:TM49_RS12830
uniprot id: A0A0D5LSN3
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS04115
gene id: 1486262:TM49_RS04115
uniprot id: A0A0D5LVF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS15655
gene id: 1486262:TM49_RS15655
uniprot id: A0A0D5LS33
names: Similarity
messages: Belongs to the ModE family.

1486262:TM49 RS15625
gene id: 1486262:TM49_RS15625
uniprot id: A0A0D5LS28
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1486262:TM49 RS17210
gene id: 1486262:TM49_RS17210
uniprot id: A0A0D5LS57
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

1486262:TM49 RS14565
gene id: 1486262:TM49_RS14565
uniprot id: A0A0D5LRP7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1486262:TM49 RS00925
gene id: 1486262:TM49_RS00925
uniprot id: A0A0D5LML8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1486262:TM49 RS22205
gene id: 1486262:TM49_RS22205
uniprot id: A0A0D5LU67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1486262:TM49 RS12480
gene id: 1486262:TM49_RS12480
uniprot id: A0A0D5LQT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS14395
gene id: 1486262:TM49_RS14395
uniprot id: A0A0D5LS39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1486262:TM49 RS07185
gene id: 1486262:TM49_RS07185
uniprot id: A0A0D5LMU2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS08375
gene id: 1486262:TM49_RS08375
uniprot id: A0A0D5LQS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS00680
gene id: 1486262:TM49_RS00680
uniprot id: A0A0D5LKQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS04960
gene id: 1486262:TM49_RS04960
uniprot id: A0A0D5LMJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1486262:TM49 RS13910
gene id: 1486262:TM49_RS13910
uniprot id: A0A0D5LRG7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1486262:TM49 RS01940
gene id: 1486262:TM49_RS01940
uniprot id: A0A0D5LL73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1486262:TM49 RS15995
gene id: 1486262:TM49_RS15995
uniprot id: A0A0D5LRQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1486262:TM49 RS06260
gene id: 1486262:TM49_RS06260
uniprot id: A0A0D5LUR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS05240
gene id: 1486262:TM49_RS05240
uniprot id: A0A0D5LM44
names: Similarity
messages: Belongs to the sulfatase family.

1486262:TM49 RS21530
gene id: 1486262:TM49_RS21530
uniprot id: A0A0D5LXB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1486262:TM49 RS21670
gene id: 1486262:TM49_RS21670
uniprot id: A0A0D5LVA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1486262:TM49 RS13285
gene id: 1486262:TM49_RS13285
uniprot id: A0A0D5LXL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS21005
gene id: 1486262:TM49_RS21005
uniprot id: A0A0D5LU51
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS14850
gene id: 1486262:TM49_RS14850
uniprot id: A0A0D5LR11
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1486262:TM49 RS18915
gene id: 1486262:TM49_RS18915
uniprot id: A0A0D5LTG6
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS06875
gene id: 1486262:TM49_RS06875
uniprot id: A0A0D5LNZ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS03600
gene id: 1486262:TM49_RS03600
uniprot id: A0A0D5LNU7
names: Similarity
messages: Belongs to the peptidase C59 family.

1486262:TM49 RS05255
gene id: 1486262:TM49_RS05255
uniprot id: A0A0D5LM01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS02590
gene id: 1486262:TM49_RS02590
uniprot id: A0A0D5LM25
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1486262:TM49 RS00100
gene id: 1486262:TM49_RS00100
uniprot id: A0A0D5LJS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1486262:TM49 RS14995
gene id: 1486262:TM49_RS14995
uniprot id: A0A0D5LRD1
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1486262:TM49 RS14530
gene id: 1486262:TM49_RS14530
uniprot id: A0A0D5LQX0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1486262:TM49 RS07175
gene id: 1486262:TM49_RS07175
uniprot id: A0A0D5LQB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS10135
gene id: 1486262:TM49_RS10135
uniprot id: A0A0D5LV10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1486262:TM49 RS14170
gene id: 1486262:TM49_RS14170
uniprot id: A0A0D5LRJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1486262:TM49 RS04905
gene id: 1486262:TM49_RS04905
uniprot id: A0A0D5LPD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1486262:TM49 RS04340
gene id: 1486262:TM49_RS04340
uniprot id: A0A0D5LMB2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS20625
gene id: 1486262:TM49_RS20625
uniprot id: A0A0D5LUU7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1486262:TM49 RS22095
gene id: 1486262:TM49_RS22095
uniprot id: A0A0D5LWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS19925
gene id: 1486262:TM49_RS19925
uniprot id: A0A0D5LVM9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1486262:TM49 RS02995
gene id: 1486262:TM49_RS02995
uniprot id: A0A0D5LMB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1486262:TM49 RS21115
gene id: 1486262:TM49_RS21115
uniprot id: A0A0D5LU66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1486262:TM49 RS16685
gene id: 1486262:TM49_RS16685
uniprot id: A0A0D5LUC8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1486262:TM49 RS18900
gene id: 1486262:TM49_RS18900
uniprot id: A0A0D5LU24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1486262:TM49 RS02935
gene id: 1486262:TM49_RS02935
uniprot id: A0A0D5LMA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS01350
gene id: 1486262:TM49_RS01350
uniprot id: A0A0D5LKZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS20900
gene id: 1486262:TM49_RS20900
uniprot id: A0A0D5LWV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS20500
gene id: 1486262:TM49_RS20500
uniprot id: A0A0D5LVV1
names: Similarity
messages: Belongs to the peptidase C59 family.

1486262:TM49 RS12625
gene id: 1486262:TM49_RS12625
uniprot id: A0A0D5LQ17
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1486262:TM49 RS06255
gene id: 1486262:TM49_RS06255
uniprot id: A0A0D5LN88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS21595
gene id: 1486262:TM49_RS21595
uniprot id: A0A0D5LUM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1486262:TM49 RS15670
gene id: 1486262:TM49_RS15670
uniprot id: A0A0D5LTS9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS18765
gene id: 1486262:TM49_RS18765
uniprot id: A0A0D5LTE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1486262:TM49 RS09775
gene id: 1486262:TM49_RS09775
uniprot id: A0A0D5LP53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS20865
gene id: 1486262:TM49_RS20865
uniprot id: A0A0D5LUC1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1486262:TM49 RS18315
gene id: 1486262:TM49_RS18315
uniprot id: A0A0D5LWZ4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1486262:TM49 RS12070
gene id: 1486262:TM49_RS12070
uniprot id: A0A0D5LVV4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS16285
gene id: 1486262:TM49_RS16285
uniprot id: A0A0D5LS36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

1486262:TM49 RS21335
gene id: 1486262:TM49_RS21335
uniprot id: A0A0D5LUI0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1486262:TM49 RS08905
gene id: 1486262:TM49_RS08905
uniprot id: A0A0D5LR09
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1486262:TM49 RS15145
gene id: 1486262:TM49_RS15145
uniprot id: A0A0D5LXR8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1486262:TM49 RS15285
gene id: 1486262:TM49_RS15285
uniprot id: A0A0D5LRH2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1486262:TM49 RS05490
gene id: 1486262:TM49_RS05490
uniprot id: A0A0D5LMU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1486262:TM49 RS22175
gene id: 1486262:TM49_RS22175
uniprot id: A0A0D5LUZ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS10200
gene id: 1486262:TM49_RS10200
uniprot id: A0A0D5LRJ7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1486262:TM49 RS13350
gene id: 1486262:TM49_RS13350
uniprot id: A0A0D5LQG0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

1486262:TM49 RS03520
gene id: 1486262:TM49_RS03520
uniprot id: A0A0D5LMH5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1486262:TM49 RS02665
gene id: 1486262:TM49_RS02665
uniprot id: A0A0D5LKV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS10145
gene id: 1486262:TM49_RS10145
uniprot id: A0A0D5LRI9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1486262:TM49 RS14495
gene id: 1486262:TM49_RS14495
uniprot id: A0A0D5LRN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1486262:TM49 RS10380
gene id: 1486262:TM49_RS10380
uniprot id: A0A0D5LRM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1486262:TM49 RS12655
gene id: 1486262:TM49_RS12655
uniprot id: A0A0D5LQ21
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS07505
gene id: 1486262:TM49_RS07505
uniprot id: A0A0D5LN59
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS08100
gene id: 1486262:TM49_RS08100
uniprot id: A0A0D5LQM7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1486262:TM49 RS00400
gene id: 1486262:TM49_RS00400
uniprot id: A0A0D5LUA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1486262:TM49 RS18230
gene id: 1486262:TM49_RS18230
uniprot id: A0A0D5LWK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1486262:TM49 RS17930
gene id: 1486262:TM49_RS17930
uniprot id: A0A0D5LUT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1486262:TM49 RS00450
gene id: 1486262:TM49_RS00450
uniprot id: A0A0D5LL52
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1486262:TM49 RS03930
gene id: 1486262:TM49_RS03930
uniprot id: A0A0D5LM57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS01325
gene id: 1486262:TM49_RS01325
uniprot id: A0A0D5LKZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1486262:TM49 RS21540
gene id: 1486262:TM49_RS21540
uniprot id: A0A0D5LUC7
names: Similarity
messages: Belongs to the UPF0174 family.

1486262:TM49 RS06295
gene id: 1486262:TM49_RS06295
uniprot id: A0A0D5LMN8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1486262:TM49 RS16345
gene id: 1486262:TM49_RS16345
uniprot id: A0A0D5LU73
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS15080
gene id: 1486262:TM49_RS15080
uniprot id: A0A0D5LRV9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1486262:TM49 RS00960
gene id: 1486262:TM49_RS00960
uniprot id: A0A0D5LK51
names: Function
names: Similarity
messages: Belongs to the amidase family.
messages: Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).

1486262:TM49 RS11195
gene id: 1486262:TM49_RS11195
uniprot id: A0A0D5LPR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1486262:TM49 RS11235
gene id: 1486262:TM49_RS11235
uniprot id: A0A0D5LQT3
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1486262:TM49 RS03435
gene id: 1486262:TM49_RS03435
uniprot id: A0A0D5LL93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS11005
gene id: 1486262:TM49_RS11005
uniprot id: A0A0D5LRU6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1486262:TM49 RS15455
gene id: 1486262:TM49_RS15455
uniprot id: A0A0D5LTQ1
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

1486262:TM49 RS19610
gene id: 1486262:TM49_RS19610
uniprot id: A0A0D5LT64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1486262:TM49 RS10125
gene id: 1486262:TM49_RS10125
uniprot id: A0A0D5LPU7
names: Similarity
messages: Belongs to the ArsC family.

1486262:TM49 RS14760
gene id: 1486262:TM49_RS14760
uniprot id: A0A0D5LR00
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1486262:TM49 RS02365
gene id: 1486262:TM49_RS02365
uniprot id: A0A0D5LLE0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1486262:TM49 RS10040
gene id: 1486262:TM49_RS10040
uniprot id: A0A0D5LQA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS06045
gene id: 1486262:TM49_RS06045
uniprot id: A0A0D5LNM7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS15935
gene id: 1486262:TM49_RS15935
uniprot id: A0A0D5LRP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS06225
gene id: 1486262:TM49_RS06225
uniprot id: A0A0D5LW40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1486262:TM49 RS17590
gene id: 1486262:TM49_RS17590
uniprot id: A0A0D5LWJ3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1486262:TM49 RS10350
gene id: 1486262:TM49_RS10350
uniprot id: A0A0D5LV14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1486262:TM49 RS14905
gene id: 1486262:TM49_RS14905
uniprot id: A0A0D5LSB9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1486262:TM49 RS21920
gene id: 1486262:TM49_RS21920
uniprot id: A0A0D5LWD4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS03215
gene id: 1486262:TM49_RS03215
uniprot id: A0A0D5LLA1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1486262:TM49 RS18395
gene id: 1486262:TM49_RS18395
uniprot id: A0A0D5LSX7
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1486262:TM49 RS09065
gene id: 1486262:TM49_RS09065
uniprot id: A0A0D5LPD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS02730
gene id: 1486262:TM49_RS02730
uniprot id: A0A0D5LL22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS10780
gene id: 1486262:TM49_RS10780
uniprot id: A0A0D5LQ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS05930
gene id: 1486262:TM49_RS05930
uniprot id: A0A0D5LPS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1486262:TM49 RS00115
gene id: 1486262:TM49_RS00115
uniprot id: A0A0D5LL05
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1486262:TM49 RS17780
gene id: 1486262:TM49_RS17780
uniprot id: A0A0D5LUR7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1486262:TM49 RS18240
gene id: 1486262:TM49_RS18240
uniprot id: A0A0D5LSJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS09810
gene id: 1486262:TM49_RS09810
uniprot id: A0A0D5LQ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1486262:TM49 RS11505
gene id: 1486262:TM49_RS11505
uniprot id: A0A0D5LPV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1486262:TM49 RS11325
gene id: 1486262:TM49_RS11325
uniprot id: A0A0D5LPI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS02755
gene id: 1486262:TM49_RS02755
uniprot id: A0A0D5LLP4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS19690
gene id: 1486262:TM49_RS19690
uniprot id: A0A0D5LT80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

1486262:TM49 RS04945
gene id: 1486262:TM49_RS04945
uniprot id: A0A0D5LPD6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS21895
gene id: 1486262:TM49_RS21895
uniprot id: A0A0D5LWC9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS16340
gene id: 1486262:TM49_RS16340
uniprot id: A0A0D5LT15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1486262:TM49 RS20185
gene id: 1486262:TM49_RS20185
uniprot id: A0A0D5LVR2
names: Similarity
messages: Belongs to the FGGY kinase family.

1486262:TM49 RS18460
gene id: 1486262:TM49_RS18460
uniprot id: A0A0D5LSM5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1486262:TM49 RS03935
gene id: 1486262:TM49_RS03935
uniprot id: A0A0D5LLK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS16435
gene id: 1486262:TM49_RS16435
uniprot id: A0A0D5LS63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1486262:TM49 RS02950
gene id: 1486262:TM49_RS02950
uniprot id: A0A0D5LL28
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS14770
gene id: 1486262:TM49_RS14770
uniprot id: A0A0D5LRA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1486262:TM49 RS18055
gene id: 1486262:TM49_RS18055
uniprot id: A0A0D5LSS8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS15060
gene id: 1486262:TM49_RS15060
uniprot id: A0A0D5LSE3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1486262:TM49 RS11715
gene id: 1486262:TM49_RS11715
uniprot id: A0A0D5LS45
names: Similarity
messages: Belongs to the sulfatase family.

1486262:TM49 RS17845
gene id: 1486262:TM49_RS17845
uniprot id: A0A0D5LT18
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1486262:TM49 RS20540
gene id: 1486262:TM49_RS20540
uniprot id: A0A0D5LTJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1486262:TM49 RS18050
gene id: 1486262:TM49_RS18050
uniprot id: A0A0D5LT43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1486262:TM49 RS14295
gene id: 1486262:TM49_RS14295
uniprot id: A0A0D5LS25
names: Similarity
messages: Belongs to the CFA/CMAS family.

1486262:TM49 RS10210
gene id: 1486262:TM49_RS10210
uniprot id: A0A0D5LP07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1486262:TM49 RS21410
gene id: 1486262:TM49_RS21410
uniprot id: A0A0D5LW04
names: Similarity
messages: Belongs to the peptidase M24B family.

1486262:TM49 RS05680
gene id: 1486262:TM49_RS05680
uniprot id: A0A0D5LPP1
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS20300
gene id: 1486262:TM49_RS20300
uniprot id: A0A0D5LUR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1486262:TM49 RS15405
gene id: 1486262:TM49_RS15405
uniprot id: A0A0D5LRI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.

1486262:TM49 RS11230
gene id: 1486262:TM49_RS11230
uniprot id: A0A0D5LPR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1486262:TM49 RS00490
gene id: 1486262:TM49_RS00490
uniprot id: A0A0D5LKN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1486262:TM49 RS00740
gene id: 1486262:TM49_RS00740
uniprot id: A0A0D5LK27
names: Similarity
messages: Belongs to the hyi family.

1486262:TM49 RS14405
gene id: 1486262:TM49_RS14405
uniprot id: A0A0D5LQU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1486262:TM49 RS02480
gene id: 1486262:TM49_RS02480
uniprot id: A0A0D5LKW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS18505
gene id: 1486262:TM49_RS18505
uniprot id: A0A0D5LV13
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1486262:TM49 RS04095
gene id: 1486262:TM49_RS04095
uniprot id: A0A0D5LMQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS18825
gene id: 1486262:TM49_RS18825
uniprot id: A0A0D5LTF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1486262:TM49 RS08820
gene id: 1486262:TM49_RS08820
uniprot id: A0A0D5LQZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS19505
gene id: 1486262:TM49_RS19505
uniprot id: A0A0D5LTG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1486262:TM49 RS08465
gene id: 1486262:TM49_RS08465
uniprot id: A0A0D5LNA6
names: Similarity
messages: Belongs to the peptidase S33 family.

1486262:TM49 RS06280
gene id: 1486262:TM49_RS06280
uniprot id: A0A0D5LMH7
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1486262:TM49 RS10355
gene id: 1486262:TM49_RS10355
uniprot id: A0A0D5LP31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1486262:TM49 RS05350
gene id: 1486262:TM49_RS05350
uniprot id: A0A0D5LPJ3
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS13385
gene id: 1486262:TM49_RS13385
uniprot id: A0A0D5LQR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1486262:TM49 RS02395
gene id: 1486262:TM49_RS02395
uniprot id: A0A0D5LLE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1486262:TM49 RS05865
gene id: 1486262:TM49_RS05865
uniprot id: A0A0D5LM86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1486262:TM49 RS19170
gene id: 1486262:TM49_RS19170
uniprot id: A0A0D5LU59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS07765
gene id: 1486262:TM49_RS07765
uniprot id: A0A0D5LQH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1486262:TM49 RS12620
gene id: 1486262:TM49_RS12620
uniprot id: A0A0D5LSG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1486262:TM49 RS06820
gene id: 1486262:TM49_RS06820
uniprot id: A0A0D5LQ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS05570
gene id: 1486262:TM49_RS05570
uniprot id: A0A0D5LVI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1486262:TM49 RS07500
gene id: 1486262:TM49_RS07500
uniprot id: A0A0D5LNP6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS18555
gene id: 1486262:TM49_RS18555
uniprot id: A0A0D5LTY3
names: Similarity
messages: Belongs to the peptidase C40 family.

1486262:TM49 RS16610
gene id: 1486262:TM49_RS16610
uniprot id: A0A0D5LSL9
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1486262:TM49 RS00380
gene id: 1486262:TM49_RS00380
uniprot id: A0A0D5LJX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS17770
gene id: 1486262:TM49_RS17770
uniprot id: A0A0D5LVJ3
names: Similarity
messages: Belongs to the HesB/IscA family.

1486262:TM49 RS20450
gene id: 1486262:TM49_RS20450
uniprot id: A0A0D5LTX1
names: Similarity
messages: Belongs to the ArsC family.

1486262:TM49 RS04600
gene id: 1486262:TM49_RS04600
uniprot id: A0A0D5LP90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS18305
gene id: 1486262:TM49_RS18305
uniprot id: A0A0D5LT76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1486262:TM49 RS20040
gene id: 1486262:TM49_RS20040
uniprot id: A0A0D5LVP9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1486262:TM49 RS16210
gene id: 1486262:TM49_RS16210
uniprot id: A0A0D5LRS5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1486262:TM49 RS00870
gene id: 1486262:TM49_RS00870
uniprot id: A0A0D5LK43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS04550
gene id: 1486262:TM49_RS04550
uniprot id: A0A0D5LV95
names: Similarity
messages: Belongs to the KduI family.

1486262:TM49 RS13480
gene id: 1486262:TM49_RS13480
uniprot id: A0A0D5LSX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1486262:TM49 RS02120
gene id: 1486262:TM49_RS02120
uniprot id: A0A0D5LKM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1486262:TM49 RS14650
gene id: 1486262:TM49_RS14650
uniprot id: A0A0D5LQY7
names: Similarity
messages: Belongs to the YicC/YloC family.

1486262:TM49 RS22155
gene id: 1486262:TM49_RS22155
uniprot id: A0A0D5LVH3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1486262:TM49 RS02725
gene id: 1486262:TM49_RS02725
uniprot id: A0A0D5LLN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS11035
gene id: 1486262:TM49_RS11035
uniprot id: A0A0D5LVS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1486262:TM49 RS17060
gene id: 1486262:TM49_RS17060
uniprot id: A0A0D5LTC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1486262:TM49 RS18650
gene id: 1486262:TM49_RS18650
uniprot id: A0A0D5LT21
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS10585
gene id: 1486262:TM49_RS10585
uniprot id: A0A0D5LP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS05540
gene id: 1486262:TM49_RS05540
uniprot id: A0A0D5LPM0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1486262:TM49 RS14845
gene id: 1486262:TM49_RS14845
uniprot id: A0A0D5LTF8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1486262:TM49 RS13325
gene id: 1486262:TM49_RS13325
uniprot id: A0A0D5LQF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1486262:TM49 RS19930
gene id: 1486262:TM49_RS19930
uniprot id: A0A0D5LTB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1486262:TM49 RS10240
gene id: 1486262:TM49_RS10240
uniprot id: A0A0D5LRK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1486262:TM49 RS15775
gene id: 1486262:TM49_RS15775
uniprot id: A0A0D5LRD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1486262:TM49 RS21440
gene id: 1486262:TM49_RS21440
uniprot id: A0A0D5LTV7
names: Similarity
messages: Belongs to the DprA/Smf family.

1486262:TM49 RS09060
gene id: 1486262:TM49_RS09060
uniprot id: A0A0D5LNI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS09905
gene id: 1486262:TM49_RS09905
uniprot id: A0A0D5LRG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS20600
gene id: 1486262:TM49_RS20600
uniprot id: A0A0D5LX87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1486262:TM49 RS18440
gene id: 1486262:TM49_RS18440
uniprot id: A0A0D5LVP2
names: Similarity
messages: Belongs to the UPF0386 family.

1486262:TM49 RS20165
gene id: 1486262:TM49_RS20165
uniprot id: A0A0D5LTS2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1486262:TM49 RS03530
gene id: 1486262:TM49_RS03530
uniprot id: A0A0D5LLA9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS16150
gene id: 1486262:TM49_RS16150
uniprot id: A0A0D5LRR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1486262:TM49 RS08760
gene id: 1486262:TM49_RS08760
uniprot id: A0A0D5LNN1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1486262:TM49 RS04030
gene id: 1486262:TM49_RS04030
uniprot id: A0A0D5LLL9
names: Subcellular Location Annotation
messages: Cell inner membrane

1486262:TM49 RS17925
gene id: 1486262:TM49_RS17925
uniprot id: A0A0D5LTN7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS20660
gene id: 1486262:TM49_RS20660
uniprot id: A0A0D5LTK9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS05520
gene id: 1486262:TM49_RS05520
uniprot id: A0A0D5LMU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1486262:TM49 RS13190
gene id: 1486262:TM49_RS13190
uniprot id: A0A0D5LQD9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1486262:TM49 RS14480
gene id: 1486262:TM49_RS14480
uniprot id: A0A0D5LS54
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1486262:TM49 RS04425
gene id: 1486262:TM49_RS04425
uniprot id: A0A0D5LMV7
names: Similarity
messages: Belongs to the RelE toxin family.

1486262:TM49 RS18345
gene id: 1486262:TM49_RS18345
uniprot id: A0A0D5LTV0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1486262:TM49 RS11290
gene id: 1486262:TM49_RS11290
uniprot id: A0A0D5LPI0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1486262:TM49 RS08570
gene id: 1486262:TM49_RS08570
uniprot id: A0A0D5LP44
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS19875
gene id: 1486262:TM49_RS19875
uniprot id: A0A0D5LTA8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1486262:TM49 RS07510
gene id: 1486262:TM49_RS07510
uniprot id: A0A0D5LP77
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1486262:TM49 RS19185
gene id: 1486262:TM49_RS19185
uniprot id: A0A0D5LTK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1486262:TM49 RS12005
gene id: 1486262:TM49_RS12005
uniprot id: A0A0D5LQL1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS16155
gene id: 1486262:TM49_RS16155
uniprot id: A0A0D5LSF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1486262:TM49 RS11895
gene id: 1486262:TM49_RS11895
uniprot id: A0A0D5LPR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1486262:TM49 RS15305
gene id: 1486262:TM49_RS15305
uniprot id: A0A0D5LR79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1486262:TM49 RS13450
gene id: 1486262:TM49_RS13450
uniprot id: A0A0D5LRS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1486262:TM49 RS14510
gene id: 1486262:TM49_RS14510
uniprot id: A0A0D5LR69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1486262:TM49 RS18335
gene id: 1486262:TM49_RS18335
uniprot id: A0A0D5LT82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1486262:TM49 RS04195
gene id: 1486262:TM49_RS04195
uniprot id: A0A0D5LP30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1486262:TM49 RS03475
gene id: 1486262:TM49_RS03475
uniprot id: A0A0D5LLZ9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS10920
gene id: 1486262:TM49_RS10920
uniprot id: A0A0D5LQ52
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1486262:TM49 RS10310
gene id: 1486262:TM49_RS10310
uniprot id: A0A0D5LQE0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1486262:TM49 RS01120
gene id: 1486262:TM49_RS01120
uniprot id: A0A0D5LK72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1486262:TM49 RS08380
gene id: 1486262:TM49_RS08380
uniprot id: A0A0D5LN91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS22120
gene id: 1486262:TM49_RS22120
uniprot id: A0A0D5LUL7
names: Similarity
messages: Belongs to the DapA family.

1486262:TM49 RS08525
gene id: 1486262:TM49_RS08525
uniprot id: A0A0D5LX93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS18510
gene id: 1486262:TM49_RS18510
uniprot id: A0A0D5LSN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1486262:TM49 RS21890
gene id: 1486262:TM49_RS21890
uniprot id: A0A0D5LVD4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS17800
gene id: 1486262:TM49_RS17800
uniprot id: A0A0D5LTL7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1486262:TM49 RS16330
gene id: 1486262:TM49_RS16330
uniprot id: A0A0D5LSI2
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1486262:TM49 RS16980
gene id: 1486262:TM49_RS16980
uniprot id: A0A0D5LS30
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1486262:TM49 RS10875
gene id: 1486262:TM49_RS10875
uniprot id: A0A0D5LPB2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1486262:TM49 RS02320
gene id: 1486262:TM49_RS02320
uniprot id: A0A0D5LLD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1486262:TM49 RS08165
gene id: 1486262:TM49_RS08165
uniprot id: A0A0D5LQN7
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1486262:TM49 RS15920
gene id: 1486262:TM49_RS15920
uniprot id: A0A0D5LTW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1486262:TM49 RS21860
gene id: 1486262:TM49_RS21860
uniprot id: A0A0D5LWC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1486262:TM49 RS01305
gene id: 1486262:TM49_RS01305
uniprot id: A0A0D5LKE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1486262:TM49 RS00590
gene id: 1486262:TM49_RS00590
uniprot id: A0A0D5LWN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1486262:TM49 RS19165
gene id: 1486262:TM49_RS19165
uniprot id: A0A0D5LT83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS16960
gene id: 1486262:TM49_RS16960
uniprot id: A0A0D5LTA9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1486262:TM49 RS08155
gene id: 1486262:TM49_RS08155
uniprot id: A0A0D5LNE5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1486262:TM49 RS11530
gene id: 1486262:TM49_RS11530
uniprot id: A0A0D5LQD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS08420
gene id: 1486262:TM49_RS08420
uniprot id: A0A0D5LNI5
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS20075
gene id: 1486262:TM49_RS20075
uniprot id: A0A0D5LUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1486262:TM49 RS10635
gene id: 1486262:TM49_RS10635
uniprot id: A0A0D5LP71
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS22060
gene id: 1486262:TM49_RS22060
uniprot id: A0A0D5LUK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1486262:TM49 RS01415
gene id: 1486262:TM49_RS01415
uniprot id: A0A0D5LKC0
names: Similarity
messages: Belongs to the UPF0276 family.

1486262:TM49 RS12700
gene id: 1486262:TM49_RS12700
uniprot id: A0A0D5LQB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS21825
gene id: 1486262:TM49_RS21825
uniprot id: A0A0D5LVC3
names: Subcellular Location Annotation
messages: Cell inner membrane

1486262:TM49 RS18150
gene id: 1486262:TM49_RS18150
uniprot id: A0A0D5LSU4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1486262:TM49 RS21705
gene id: 1486262:TM49_RS21705
uniprot id: A0A0D5LUE9
names: Subcellular Location Annotation
messages: Membrane

1486262:TM49 RS01825
gene id: 1486262:TM49_RS01825
uniprot id: A0A0D5LKH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1486262:TM49 RS12370
gene id: 1486262:TM49_RS12370
uniprot id: A0A0D5LPY0
names: Similarity
messages: Belongs to the DapA family.

1486262:TM49 RS05740
gene id: 1486262:TM49_RS05740
uniprot id: A0A0D5LNF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1486262:TM49 RS18295
gene id: 1486262:TM49_RS18295
uniprot id: A0A0D5LUY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1486262:TM49 RS18210
gene id: 1486262:TM49_RS18210
uniprot id: A0A0D5LT62
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1486262:TM49 RS06035
gene id: 1486262:TM49_RS06035
uniprot id: A0A0D5LN50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS20395
gene id: 1486262:TM49_RS20395
uniprot id: A0A0D5LTW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1486262:TM49 RS19955
gene id: 1486262:TM49_RS19955
uniprot id: A0A0D5LTC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1486262:TM49 RS11785
gene id: 1486262:TM49_RS11785
uniprot id: A0A0D5LPP7
names: Similarity
messages: Belongs to the histone deacetylase family.

1486262:TM49 RS00840
gene id: 1486262:TM49_RS00840
uniprot id: A0A0D5LK84
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1486262:TM49 RS20880
gene id: 1486262:TM49_RS20880
uniprot id: A0A0D5LUY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1486262:TM49 RS09150
gene id: 1486262:TM49_RS09150
uniprot id: A0A0D5LNU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1486262:TM49 RS06605
gene id: 1486262:TM49_RS06605
uniprot id: A0A0D5LMT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1486262:TM49 RS14550
gene id: 1486262:TM49_RS14550
uniprot id: A0A0D5LTC5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1486262:TM49 RS11630
gene id: 1486262:TM49_RS11630
uniprot id: A0A0D5LQF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1486262:TM49 RS08180
gene id: 1486262:TM49_RS08180
uniprot id: A0A0D5LNF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1486262:TM49 RS00010
gene id: 1486262:TM49_RS00010
uniprot id: A0A0D5LJR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1486262:TM49 RS07100
gene id: 1486262:TM49_RS07100
uniprot id: A0A0D5LMT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1486262:TM49 RS19845
gene id: 1486262:TM49_RS19845
uniprot id: A0A0D5LTA3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1486262:TM49 RS19600
gene id: 1486262:TM49_RS19600
uniprot id: A0A0D5LUE5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1486262:TM49 RS00105
gene id: 1486262:TM49_RS00105
uniprot id: A0A0D5LKH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1486262:TM49 RS04440
gene id: 1486262:TM49_RS04440
uniprot id: A0A0D5LMC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1486262:TM49 RS07665
gene id: 1486262:TM49_RS07665
uniprot id: A0A0D5LN74
names: Similarity
messages: Belongs to the DapA family.

1486262:TM49 RS16310
gene id: 1486262:TM49_RS16310
uniprot id: A0A0D5LS41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1486262:TM49 RS17030
gene id: 1486262:TM49_RS17030
uniprot id: A0A0D5LTB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1486262:TM49 RS19960
gene id: 1486262:TM49_RS19960
uniprot id: A0A0D5LTZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1486262:TM49 RS10825
gene id: 1486262:TM49_RS10825
uniprot id: A0A0D5LRS6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1486262:TM49 RS11510
gene id: 1486262:TM49_RS11510
uniprot id: A0A0D5LQX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1486262:TM49 RS16540
gene id: 1486262:TM49_RS16540
uniprot id: A0A0D5LT42
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1486262:TM49 RS18370
gene id: 1486262:TM49_RS18370
uniprot id: A0A0D5LTV6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1486262:TM49 RS19540
gene id: 1486262:TM49_RS19540
uniprot id: A0A0D5LTS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1486262:TM49 RS20455
gene id: 1486262:TM49_RS20455
uniprot id: A0A0D5LUT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1486262:TM49 RS12430
gene id: 1486262:TM49_RS12430
uniprot id: A0A0D5LV69
names: Similarity
messages: Belongs to the creatininase superfamily.

1486262:TM49 RS01720
gene id: 1486262:TM49_RS01720
uniprot id: A0A0D5LKG4
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1486262:TM49 RS14920
gene id: 1486262:TM49_RS14920
uniprot id: A0A0D5LRU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1486262:TM49 RS06290
gene id: 1486262:TM49_RS06290
uniprot id: A0A0D5LVK5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1486262:TM49 RS16405
gene id: 1486262:TM49_RS16405
uniprot id: A0A0D5LSJ4
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.