146922:HEP81 RS05595
gene id: 146922:HEP81_RS05595
uniprot id: A0A7H1PTS9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

146922:HEP81 RS16565
gene id: 146922:HEP81_RS16565
uniprot id: A0A3R8R9J2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

146922:HEP81 RS26615
gene id: 146922:HEP81_RS26615
uniprot id: A0A1X4GN76
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

146922:HEP81 RS12535
gene id: 146922:HEP81_RS12535
uniprot id: A0A7H1PXR7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS28140
gene id: 146922:HEP81_RS28140
uniprot id: A0A7H1Q6H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

146922:HEP81 RS09105
gene id: 146922:HEP81_RS09105
uniprot id: A0A426SBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

146922:HEP81 RS28965
gene id: 146922:HEP81_RS28965
uniprot id: A0A3R8WZ02
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS32795
gene id: 146922:HEP81_RS32795
uniprot id: A0A1X4H4H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

146922:HEP81 RS26225
gene id: 146922:HEP81_RS26225
uniprot id: A0A1X4GNE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

146922:HEP81 RS31990
gene id: 146922:HEP81_RS31990
uniprot id: A0A7H1Q8N5
names: Similarity
messages: Belongs to the universal stress protein A family.

146922:HEP81 RS19345
gene id: 146922:HEP81_RS19345
uniprot id: A0A1X4GRL5
names: Similarity
messages: Belongs to the thioredoxin family.

146922:HEP81 RS22035
gene id: 146922:HEP81_RS22035
uniprot id: A0A7H1Q334
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

146922:HEP81 RS21015
gene id: 146922:HEP81_RS21015
uniprot id: A0A3R8WR56
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

146922:HEP81 RS16645
gene id: 146922:HEP81_RS16645
uniprot id: A0A7H1Q029
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS26985
gene id: 146922:HEP81_RS26985
uniprot id: A0A7H1Q5V3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

146922:HEP81 RS05250
gene id: 146922:HEP81_RS05250
uniprot id: A0A7H1PTL0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS16685
gene id: 146922:HEP81_RS16685
uniprot id: A0A7H1Q037
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

146922:HEP81 RS10945
gene id: 146922:HEP81_RS10945
uniprot id: A0A7H1PWV8
names: Similarity
messages: Belongs to the citrate synthase family.

146922:HEP81 RS36195
gene id: 146922:HEP81_RS36195
uniprot id: A0A7H1QB34
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

146922:HEP81 RS14390
gene id: 146922:HEP81_RS14390
uniprot id: A0A1X4H1E2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS16380
gene id: 146922:HEP81_RS16380
uniprot id: A0A3R8QE48
names: Similarity
messages: Belongs to the UPF0336 family.

146922:HEP81 RS15380
gene id: 146922:HEP81_RS15380
uniprot id: A0A7H1PZC9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS01690
gene id: 146922:HEP81_RS01690
uniprot id: A0A7H1PRJ2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

146922:HEP81 RS34895
gene id: 146922:HEP81_RS34895
uniprot id: A0A3R8WWX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

146922:HEP81 RS16245
gene id: 146922:HEP81_RS16245
uniprot id: A0A1X4GTR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

146922:HEP81 RS10225
gene id: 146922:HEP81_RS10225
uniprot id: A0A7H1PWG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS21595
gene id: 146922:HEP81_RS21595
uniprot id: A0A7H1Q2U4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

146922:HEP81 RS17800
gene id: 146922:HEP81_RS17800
uniprot id: A0A7H1Q0Q7
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

146922:HEP81 RS14095
gene id: 146922:HEP81_RS14095
uniprot id: A0A7H1PYM5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS32890
gene id: 146922:HEP81_RS32890
uniprot id: A0A7H1Q969
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

146922:HEP81 RS10220
gene id: 146922:HEP81_RS10220
uniprot id: A0A3R8QJP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS00600
gene id: 146922:HEP81_RS00600
uniprot id: A0A7H1PQX5
names: Subcellular Location Annotation
messages: Cytoplasm

146922:HEP81 RS12005
gene id: 146922:HEP81_RS12005
uniprot id: A0A7H1PXG5
names: Similarity
messages: Belongs to the UPF0102 family.

146922:HEP81 RS35190
gene id: 146922:HEP81_RS35190
uniprot id: A0A7H1QAI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

146922:HEP81 RS15850
gene id: 146922:HEP81_RS15850
uniprot id: A0A1X4GTC4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

146922:HEP81 RS25785
gene id: 146922:HEP81_RS25785
uniprot id: A0A1X4GNV8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

146922:HEP81 RS17390
gene id: 146922:HEP81_RS17390
uniprot id: A0A3R8REU9
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS04750
gene id: 146922:HEP81_RS04750
uniprot id: A0A7H1PTA7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

146922:HEP81 RS20850
gene id: 146922:HEP81_RS20850
uniprot id: A0A7H1Q2E6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

146922:HEP81 RS16240
gene id: 146922:HEP81_RS16240
uniprot id: A0A1X4GTB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

146922:HEP81 RS19325
gene id: 146922:HEP81_RS19325
uniprot id: A0A3R8RMU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

146922:HEP81 RS29470
gene id: 146922:HEP81_RS29470
uniprot id: A0A426SDX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

146922:HEP81 RS11820
gene id: 146922:HEP81_RS11820
uniprot id: A0A7H1PXC8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

146922:HEP81 RS29060
gene id: 146922:HEP81_RS29060
uniprot id: A0A3R8RIY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

146922:HEP81 RS09390
gene id: 146922:HEP81_RS09390
uniprot id: A0A7H1PVZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS17945
gene id: 146922:HEP81_RS17945
uniprot id: A0A7H1Q0T4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

146922:HEP81 RS33215
gene id: 146922:HEP81_RS33215
uniprot id: A0A7H1Q9D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

146922:HEP81 RS02405
gene id: 146922:HEP81_RS02405
uniprot id: A0A7H1PRY7
names: Function
names: Similarity
messages: Belongs to the LuxC family.
messages: LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.

146922:HEP81 RS34280
gene id: 146922:HEP81_RS34280
uniprot id: A0A3R8QKH8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS27115
gene id: 146922:HEP81_RS27115
uniprot id: A0A7H1Q5X8
names: Similarity
messages: Belongs to the UPF0246 family.

146922:HEP81 RS30190
gene id: 146922:HEP81_RS30190
uniprot id: A0A3R8WTG5
names: Caution
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS31200
gene id: 146922:HEP81_RS31200
uniprot id: A0A7H1Q881
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

146922:HEP81 RS09555
gene id: 146922:HEP81_RS09555
uniprot id: A0A426SBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS22165
gene id: 146922:HEP81_RS22165
uniprot id: A0A426RXU3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

146922:HEP81 RS34325
gene id: 146922:HEP81_RS34325
uniprot id: A0A7H1QA08
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

146922:HEP81 RS25790
gene id: 146922:HEP81_RS25790
uniprot id: A0A426S5X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

146922:HEP81 RS37305
gene id: 146922:HEP81_RS37305
uniprot id: A0A7H1QBQ4
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

146922:HEP81 RS11965
gene id: 146922:HEP81_RS11965
uniprot id: A0A1X4GVE1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS20825
gene id: 146922:HEP81_RS20825
uniprot id: A0A426S229
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

146922:HEP81 RS16515
gene id: 146922:HEP81_RS16515
uniprot id: A0A1X4GTA8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS31345
gene id: 146922:HEP81_RS31345
uniprot id: A0A3R8WT68
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

146922:HEP81 RS12035
gene id: 146922:HEP81_RS12035
uniprot id: A0A3R8S906
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

146922:HEP81 RS18410
gene id: 146922:HEP81_RS18410
uniprot id: A0A426SAN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

146922:HEP81 RS13275
gene id: 146922:HEP81_RS13275
uniprot id: A0A3R8QEX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

146922:HEP81 RS10690
gene id: 146922:HEP81_RS10690
uniprot id: A0A7H1PWQ6
names: Similarity
messages: Belongs to the peptidase C40 family.

146922:HEP81 RS07985
gene id: 146922:HEP81_RS07985
uniprot id: A0A7H1PV64
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

146922:HEP81 RS24975
gene id: 146922:HEP81_RS24975
uniprot id: A0A1X4GPB9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

146922:HEP81 RS27790
gene id: 146922:HEP81_RS27790
uniprot id: A0A7H1Q6A9
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

146922:HEP81 RS24855
gene id: 146922:HEP81_RS24855
uniprot id: A0A426S595
names: Similarity
messages: Belongs to the universal stress protein A family.

146922:HEP81 RS32280
gene id: 146922:HEP81_RS32280
uniprot id: A0A7H1Q8U2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS29650
gene id: 146922:HEP81_RS29650
uniprot id: A0A1X4GLR2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

146922:HEP81 RS11130
gene id: 146922:HEP81_RS11130
uniprot id: A0A1X4GW49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

146922:HEP81 RS30490
gene id: 146922:HEP81_RS30490
uniprot id: A0A1X4H3B2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

146922:HEP81 RS23775
gene id: 146922:HEP81_RS23775
uniprot id: A0A1X4GPX7
names: Similarity
messages: Belongs to the UPF0434 family.

146922:HEP81 RS18645
gene id: 146922:HEP81_RS18645
uniprot id: A0A7H1Q176
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS25150
gene id: 146922:HEP81_RS25150
uniprot id: A0A1X4GPG4
names: Caution
names: Similarity
messages: Belongs to the citrate synthase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS35775
gene id: 146922:HEP81_RS35775
uniprot id: A0A1X4H5R9
names: Similarity
messages: Belongs to the universal stress protein A family.

146922:HEP81 RS13625
gene id: 146922:HEP81_RS13625
uniprot id: A0A7H1PYD4
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

146922:HEP81 RS19370
gene id: 146922:HEP81_RS19370
uniprot id: A0A7H1Q1M0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS23995
gene id: 146922:HEP81_RS23995
uniprot id: A0A3R8SBL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

146922:HEP81 RS39590
gene id: 146922:HEP81_RS39590
uniprot id: A0A7H1QCZ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

146922:HEP81 RS15260
gene id: 146922:HEP81_RS15260
uniprot id: A0A7H1PZA6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS25595
gene id: 146922:HEP81_RS25595
uniprot id: A0A1X4GNZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

146922:HEP81 RS15640
gene id: 146922:HEP81_RS15640
uniprot id: A0A1X4GU08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

146922:HEP81 RS37750
gene id: 146922:HEP81_RS37750
uniprot id: A0A3R8S717
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

146922:HEP81 RS23600
gene id: 146922:HEP81_RS23600
uniprot id: A0A7H1Q3Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

146922:HEP81 RS01825
gene id: 146922:HEP81_RS01825
uniprot id: A0A3R8QBD9
names: Similarity
messages: Belongs to the AHA1 family.

146922:HEP81 RS40755
gene id: 146922:HEP81_RS40755
uniprot id: A0A7H1QDP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

146922:HEP81 RS16030
gene id: 146922:HEP81_RS16030
uniprot id: A0A1X4GTM1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

146922:HEP81 RS04850
gene id: 146922:HEP81_RS04850
uniprot id: A0A7H1PTC8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

146922:HEP81 RS05280
gene id: 146922:HEP81_RS05280
uniprot id: A0A7H1PTL6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS24095
gene id: 146922:HEP81_RS24095
uniprot id: A0A7H1Q492
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

146922:HEP81 RS05975
gene id: 146922:HEP81_RS05975
uniprot id: A0A7H1PU05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

146922:HEP81 RS16855
gene id: 146922:HEP81_RS16855
uniprot id: A0A3R8REQ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS38175
gene id: 146922:HEP81_RS38175
uniprot id: A0A7H1QC77
names: Similarity
messages: Belongs to the TPP enzyme family.

146922:HEP81 RS12845
gene id: 146922:HEP81_RS12845
uniprot id: A0A7H1PXX9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

146922:HEP81 RS26150
gene id: 146922:HEP81_RS26150
uniprot id: A0A7H1Q5E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS09905
gene id: 146922:HEP81_RS09905
uniprot id: A0A7H1PW99
names: Similarity
messages: Belongs to the peptidase C40 family.

146922:HEP81 RS11185
gene id: 146922:HEP81_RS11185
uniprot id: A0A426SB66
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

146922:HEP81 RS35540
gene id: 146922:HEP81_RS35540
uniprot id: A0A7H1QAQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
messages: Belongs to the glycosyl hydrolase 46 family.
messages: Secreted

146922:HEP81 RS04770
gene id: 146922:HEP81_RS04770
uniprot id: A0A7H1PTB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

146922:HEP81 RS13325
gene id: 146922:HEP81_RS13325
uniprot id: A0A1X4GUQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

146922:HEP81 RS23655
gene id: 146922:HEP81_RS23655
uniprot id: A0A426RX77
names: Caution
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS32830
gene id: 146922:HEP81_RS32830
uniprot id: A0A1X4H4D8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

146922:HEP81 RS24425
gene id: 146922:HEP81_RS24425
uniprot id: A0A7H1Q4F4
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS15725
gene id: 146922:HEP81_RS15725
uniprot id: A0A7H1PZJ7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS03495
gene id: 146922:HEP81_RS03495
uniprot id: A0A7H1PSK6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS31265
gene id: 146922:HEP81_RS31265
uniprot id: A0A426S6A1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

146922:HEP81 RS17625
gene id: 146922:HEP81_RS17625
uniprot id: A0A7H1Q0M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

146922:HEP81 RS32660
gene id: 146922:HEP81_RS32660
uniprot id: A0A1X4H705
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS31185
gene id: 146922:HEP81_RS31185
uniprot id: A0A7H1Q878
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

146922:HEP81 RS29050
gene id: 146922:HEP81_RS29050
uniprot id: A0A1X4GM17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

146922:HEP81 RS16090
gene id: 146922:HEP81_RS16090
uniprot id: A0A1X4GTB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

146922:HEP81 RS11480
gene id: 146922:HEP81_RS11480
uniprot id: A0A7H1PX61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

146922:HEP81 RS31425
gene id: 146922:HEP81_RS31425
uniprot id: A0A1X4H3I2
names: Caution
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS06385
gene id: 146922:HEP81_RS06385
uniprot id: A0A7H1PU88
names: Similarity
messages: Belongs to the peptidase M24B family.

146922:HEP81 RS05105
gene id: 146922:HEP81_RS05105
uniprot id: A0A3R8R8U4
names: Similarity
messages: Belongs to the peptidase S8 family.

146922:HEP81 RS28590
gene id: 146922:HEP81_RS28590
uniprot id: A0A7H1Q6R8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS28930
gene id: 146922:HEP81_RS28930
uniprot id: A0A7H1Q6Y6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

146922:HEP81 RS20100
gene id: 146922:HEP81_RS20100
uniprot id: A0A7H1Q206
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

146922:HEP81 RS14520
gene id: 146922:HEP81_RS14520
uniprot id: A0A7H1PYW0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

146922:HEP81 RS03095
gene id: 146922:HEP81_RS03095
uniprot id: A0A7H1PSC7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS34620
gene id: 146922:HEP81_RS34620
uniprot id: A0A7H1QA69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

146922:HEP81 RS16720
gene id: 146922:HEP81_RS16720
uniprot id: A0A3R8QAI5
names: Similarity
messages: Belongs to the peptidase A24 family.

146922:HEP81 RS24120
gene id: 146922:HEP81_RS24120
uniprot id: A0A3R8QFX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS20410
gene id: 146922:HEP81_RS20410
uniprot id: A0A7H1Q258
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

146922:HEP81 RS02960
gene id: 146922:HEP81_RS02960
uniprot id: A0A7H1PSA0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

146922:HEP81 RS24070
gene id: 146922:HEP81_RS24070
uniprot id: A0A7H1Q487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

146922:HEP81 RS12600
gene id: 146922:HEP81_RS12600
uniprot id: A0A7H1PXT0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

146922:HEP81 RS04775
gene id: 146922:HEP81_RS04775
uniprot id: A0A7H1PTB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

146922:HEP81 RS20940
gene id: 146922:HEP81_RS20940
uniprot id: A0A426S2C5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

146922:HEP81 RS16910
gene id: 146922:HEP81_RS16910
uniprot id: A0A7H1Q081
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS15835
gene id: 146922:HEP81_RS15835
uniprot id: A0A3R8RHP7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

146922:HEP81 RS37190
gene id: 146922:HEP81_RS37190
uniprot id: A0A7H1QBN0
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

146922:HEP81 RS28815
gene id: 146922:HEP81_RS28815
uniprot id: A0A7H1Q6W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

146922:HEP81 RS26230
gene id: 146922:HEP81_RS26230
uniprot id: A0A7H1Q5F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

146922:HEP81 RS07250
gene id: 146922:HEP81_RS07250
uniprot id: A0A7H1PUQ6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

146922:HEP81 RS04640
gene id: 146922:HEP81_RS04640
uniprot id: A0A7H1PT86
names: Similarity
messages: Belongs to the asparagine synthetase family.

146922:HEP81 RS14975
gene id: 146922:HEP81_RS14975
uniprot id: A0A1X4GTV1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

146922:HEP81 RS11945
gene id: 146922:HEP81_RS11945
uniprot id: A0A3R8RH00
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

146922:HEP81 RS12515
gene id: 146922:HEP81_RS12515
uniprot id: A0A7H1PXR3
names: Cofactor
messages: Binds 1 FAD per subunit.

146922:HEP81 RS26325
gene id: 146922:HEP81_RS26325
uniprot id: A0A426SFH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS11805
gene id: 146922:HEP81_RS11805
uniprot id: A0A7H1PXC5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

146922:HEP81 RS26015
gene id: 146922:HEP81_RS26015
uniprot id: A0A7H1Q5B3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

146922:HEP81 RS12655
gene id: 146922:HEP81_RS12655
uniprot id: A0A7H1PXU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS29110
gene id: 146922:HEP81_RS29110
uniprot id: A0A426SDT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

146922:HEP81 RS05475
gene id: 146922:HEP81_RS05475
uniprot id: A0A1X4GY66
names: Similarity
messages: Belongs to the Dps family.

146922:HEP81 RS11615
gene id: 146922:HEP81_RS11615
uniprot id: A0A1X4GVV6
names: Similarity
messages: Belongs to the ribF family.

146922:HEP81 RS24245
gene id: 146922:HEP81_RS24245
uniprot id: A0A3R8WSK9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS26105
gene id: 146922:HEP81_RS26105
uniprot id: A0A426SFX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

146922:HEP81 RS19935
gene id: 146922:HEP81_RS19935
uniprot id: A0A426SAU0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS12295
gene id: 146922:HEP81_RS12295
uniprot id: A0A7H1PXM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

146922:HEP81 RS35535
gene id: 146922:HEP81_RS35535
uniprot id: A0A7H1QAQ3
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

146922:HEP81 RS32685
gene id: 146922:HEP81_RS32685
uniprot id: A0A7H1Q928
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS31335
gene id: 146922:HEP81_RS31335
uniprot id: A0A3R8QGK1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS34180
gene id: 146922:HEP81_RS34180
uniprot id: A0A7H1Q9X9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS27810
gene id: 146922:HEP81_RS27810
uniprot id: A0A3R8WYG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

146922:HEP81 RS14615
gene id: 146922:HEP81_RS14615
uniprot id: A0A7H1PYY0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

146922:HEP81 RS27265
gene id: 146922:HEP81_RS27265
uniprot id: A0A7H1Q606
names: Similarity
messages: Belongs to the EfeM/EfeO family.

146922:HEP81 RS17085
gene id: 146922:HEP81_RS17085
uniprot id: A0A3R8QB31
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

146922:HEP81 RS36445
gene id: 146922:HEP81_RS36445
uniprot id: A0A7H1QB84
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

146922:HEP81 RS16465
gene id: 146922:HEP81_RS16465
uniprot id: A0A7H1PZZ3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS05245
gene id: 146922:HEP81_RS05245
uniprot id: A0A7H1PTK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

146922:HEP81 RS09465
gene id: 146922:HEP81_RS09465
uniprot id: A0A7H1PW11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

146922:HEP81 RS31325
gene id: 146922:HEP81_RS31325
uniprot id: A0A1X4H3H8
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

146922:HEP81 RS20065
gene id: 146922:HEP81_RS20065
uniprot id: A0A1X4GRA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

146922:HEP81 RS03825
gene id: 146922:HEP81_RS03825
uniprot id: A0A1X4GZ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS05285
gene id: 146922:HEP81_RS05285
uniprot id: A0A7H1PTL7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

146922:HEP81 RS24965
gene id: 146922:HEP81_RS24965
uniprot id: A0A3R8RC84
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS21095
gene id: 146922:HEP81_RS21095
uniprot id: A0A1X4GR80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

146922:HEP81 RS06240
gene id: 146922:HEP81_RS06240
uniprot id: A0A7H1PU58
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

146922:HEP81 RS18350
gene id: 146922:HEP81_RS18350
uniprot id: A0A7H1Q115
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

146922:HEP81 RS34015
gene id: 146922:HEP81_RS34015
uniprot id: A0A7H1Q9U5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

146922:HEP81 RS24910
gene id: 146922:HEP81_RS24910
uniprot id: A0A7H1Q4P6
names: Similarity
messages: Belongs to the group II decarboxylase family.

146922:HEP81 RS31680
gene id: 146922:HEP81_RS31680
uniprot id: A0A1X4H3S4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

146922:HEP81 RS20400
gene id: 146922:HEP81_RS20400
uniprot id: A0A3R8QEQ3
names: Caution
names: Similarity
messages: Belongs to the PstS family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS24715
gene id: 146922:HEP81_RS24715
uniprot id: A0A7H1Q4L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS16110
gene id: 146922:HEP81_RS16110
uniprot id: A0A1X4GTD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

146922:HEP81 RS15035
gene id: 146922:HEP81_RS15035
uniprot id: A0A7H1PZ62
names: Similarity
messages: Belongs to the ABC transporter superfamily.

146922:HEP81 RS29730
gene id: 146922:HEP81_RS29730
uniprot id: A0A1X4GLN8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS28440
gene id: 146922:HEP81_RS28440
uniprot id: A0A7H1Q6N8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS09570
gene id: 146922:HEP81_RS09570
uniprot id: A0A7H1PW31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

146922:HEP81 RS06075
gene id: 146922:HEP81_RS06075
uniprot id: A0A7H1PU25
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS31460
gene id: 146922:HEP81_RS31460
uniprot id: A0A7H1Q8D3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS16675
gene id: 146922:HEP81_RS16675
uniprot id: A0A1X4GTC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS04245
gene id: 146922:HEP81_RS04245
uniprot id: A0A426S007
names: Similarity
messages: Belongs to the thioredoxin family.

146922:HEP81 RS35810
gene id: 146922:HEP81_RS35810
uniprot id: A0A7H1QAV6
names: Similarity
messages: Belongs to the XFP family.

146922:HEP81 RS31420
gene id: 146922:HEP81_RS31420
uniprot id: A0A3R8SCC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

146922:HEP81 RS33415
gene id: 146922:HEP81_RS33415
uniprot id: A0A7H1Q9H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

146922:HEP81 RS38370
gene id: 146922:HEP81_RS38370
uniprot id: A0A7H1QCB3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

146922:HEP81 RS09185
gene id: 146922:HEP81_RS09185
uniprot id: A0A7H1PVV5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

146922:HEP81 RS08960
gene id: 146922:HEP81_RS08960
uniprot id: A0A426SBV2
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

146922:HEP81 RS11715
gene id: 146922:HEP81_RS11715
uniprot id: A0A7H1PXA7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

146922:HEP81 RS09590
gene id: 146922:HEP81_RS09590
uniprot id: A0A7H1PW35
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

146922:HEP81 RS18185
gene id: 146922:HEP81_RS18185
uniprot id: A0A426SAG5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

146922:HEP81 RS13180
gene id: 146922:HEP81_RS13180
uniprot id: A0A7H1PY46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

146922:HEP81 RS27315
gene id: 146922:HEP81_RS27315
uniprot id: A0A7H1Q616
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS06950
gene id: 146922:HEP81_RS06950
uniprot id: A0A7H1PUJ7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

146922:HEP81 RS22530
gene id: 146922:HEP81_RS22530
uniprot id: A0A7H1Q3D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

146922:HEP81 RS17770
gene id: 146922:HEP81_RS17770
uniprot id: A0A7H1Q0Q1
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

146922:HEP81 RS12045
gene id: 146922:HEP81_RS12045
uniprot id: A0A7H1PXH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

146922:HEP81 RS36225
gene id: 146922:HEP81_RS36225
uniprot id: A0A7H1QB40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

146922:HEP81 RS12770
gene id: 146922:HEP81_RS12770
uniprot id: A0A3R8R972
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

146922:HEP81 RS28605
gene id: 146922:HEP81_RS28605
uniprot id: A0A7H1Q6S1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS15430
gene id: 146922:HEP81_RS15430
uniprot id: A0A7H1PZD9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

146922:HEP81 RS18330
gene id: 146922:HEP81_RS18330
uniprot id: A0A7H1Q111
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS35900
gene id: 146922:HEP81_RS35900
uniprot id: A0A7H1QAX4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

146922:HEP81 RS16045
gene id: 146922:HEP81_RS16045
uniprot id: A0A1X4GTL8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

146922:HEP81 RS22810
gene id: 146922:HEP81_RS22810
uniprot id: A0A7H1Q3I8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

146922:HEP81 RS17590
gene id: 146922:HEP81_RS17590
uniprot id: A0A7H1Q0L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

146922:HEP81 RS27950
gene id: 146922:HEP81_RS27950
uniprot id: A0A1X4GMK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS13250
gene id: 146922:HEP81_RS13250
uniprot id: A0A1X4GUR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

146922:HEP81 RS17555
gene id: 146922:HEP81_RS17555
uniprot id: A0A7H1Q0K6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS10345
gene id: 146922:HEP81_RS10345
uniprot id: A0A3R8S3X6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

146922:HEP81 RS29355
gene id: 146922:HEP81_RS29355
uniprot id: A0A7H1Q771
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

146922:HEP81 RS14280
gene id: 146922:HEP81_RS14280
uniprot id: A0A7H1PYR2
names: Similarity
messages: Belongs to the peptidase S1C family.

146922:HEP81 RS18820
gene id: 146922:HEP81_RS18820
uniprot id: A0A3R8WVL5
names: Similarity
messages: Belongs to the pirin family.

146922:HEP81 RS31350
gene id: 146922:HEP81_RS31350
uniprot id: A0A7H1Q8B1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS17230
gene id: 146922:HEP81_RS17230
uniprot id: A0A7H1Q0E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

146922:HEP81 RS21815
gene id: 146922:HEP81_RS21815
uniprot id: A0A426S2L4
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS38095
gene id: 146922:HEP81_RS38095
uniprot id: A0A7H1QC61
names: Similarity
messages: Belongs to the thioesterase family.

146922:HEP81 RS19170
gene id: 146922:HEP81_RS19170
uniprot id: A0A426SA23
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS18365
gene id: 146922:HEP81_RS18365
uniprot id: A0A7H1Q118
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

146922:HEP81 RS29990
gene id: 146922:HEP81_RS29990
uniprot id: A0A1X4GLU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

146922:HEP81 RS30500
gene id: 146922:HEP81_RS30500
uniprot id: A0A1X4H326
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS05060
gene id: 146922:HEP81_RS05060
uniprot id: A0A7H1PTH1
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

146922:HEP81 RS27745
gene id: 146922:HEP81_RS27745
uniprot id: A0A1X4GN49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

146922:HEP81 RS38105
gene id: 146922:HEP81_RS38105
uniprot id: A0A7H1QC63
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

146922:HEP81 RS16495
gene id: 146922:HEP81_RS16495
uniprot id: A0A426S1T1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS33445
gene id: 146922:HEP81_RS33445
uniprot id: A0A3R8QET4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

146922:HEP81 RS18880
gene id: 146922:HEP81_RS18880
uniprot id: A0A3R8QDN5
names: Similarity
messages: Belongs to the peptidase S11 family.

146922:HEP81 RS21275
gene id: 146922:HEP81_RS21275
uniprot id: A0A3R8Q881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

146922:HEP81 RS37285
gene id: 146922:HEP81_RS37285
uniprot id: A0A7H1QBQ0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS35680
gene id: 146922:HEP81_RS35680
uniprot id: A0A3R8QD10
names: Similarity
messages: Belongs to the HupF/HypC family.

146922:HEP81 RS39265
gene id: 146922:HEP81_RS39265
uniprot id: A0A7H1QCT3
names: Similarity
messages: Belongs to the PqqA family.

146922:HEP81 RS16100
gene id: 146922:HEP81_RS16100
uniprot id: A0A1X4H192
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

146922:HEP81 RS03940
gene id: 146922:HEP81_RS03940
uniprot id: A0A7H1PSU5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS06180
gene id: 146922:HEP81_RS06180
uniprot id: A0A3R8QFN7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

146922:HEP81 RS16615
gene id: 146922:HEP81_RS16615
uniprot id: A0A7H1Q023
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

146922:HEP81 RS28960
gene id: 146922:HEP81_RS28960
uniprot id: A0A7H1Q6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

146922:HEP81 RS34935
gene id: 146922:HEP81_RS34935
uniprot id: A0A7H1QAD2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS27410
gene id: 146922:HEP81_RS27410
uniprot id: A0A7H1Q635
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS39250
gene id: 146922:HEP81_RS39250
uniprot id: A0A7H1QCT0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

146922:HEP81 RS24380
gene id: 146922:HEP81_RS24380
uniprot id: A0A3R8QAY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

146922:HEP81 RS03325
gene id: 146922:HEP81_RS03325
uniprot id: A0A3R8Q5Y8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS25980
gene id: 146922:HEP81_RS25980
uniprot id: A0A7H1Q5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

146922:HEP81 RS21285
gene id: 146922:HEP81_RS21285
uniprot id: A0A1X4GQN3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS23440
gene id: 146922:HEP81_RS23440
uniprot id: A0A7H1Q3W5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

146922:HEP81 RS28410
gene id: 146922:HEP81_RS28410
uniprot id: A0A3R8QG48
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS34245
gene id: 146922:HEP81_RS34245
uniprot id: A0A7H1Q9Z2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS25775
gene id: 146922:HEP81_RS25775
uniprot id: A0A7H1Q567
names: Cofactor
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS28260
gene id: 146922:HEP81_RS28260
uniprot id: A0A7H1Q6K2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS13455
gene id: 146922:HEP81_RS13455
uniprot id: A0A7H1PYA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

146922:HEP81 RS27935
gene id: 146922:HEP81_RS27935
uniprot id: A0A3R8RJ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

146922:HEP81 RS16295
gene id: 146922:HEP81_RS16295
uniprot id: A0A426S1U7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

146922:HEP81 RS12385
gene id: 146922:HEP81_RS12385
uniprot id: A0A1X4H1S0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS18475
gene id: 146922:HEP81_RS18475
uniprot id: A0A426SAG3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS28760
gene id: 146922:HEP81_RS28760
uniprot id: A0A3R8RJ08
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

146922:HEP81 RS28705
gene id: 146922:HEP81_RS28705
uniprot id: A0A7H1Q6U2
names: Similarity
messages: Belongs to the group II decarboxylase family.

146922:HEP81 RS10850
gene id: 146922:HEP81_RS10850
uniprot id: A0A7H1PWT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS28615
gene id: 146922:HEP81_RS28615
uniprot id: A0A7H1Q6S3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS22335
gene id: 146922:HEP81_RS22335
uniprot id: A0A3R8RVV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS29455
gene id: 146922:HEP81_RS29455
uniprot id: A0A7H1Q791
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS16035
gene id: 146922:HEP81_RS16035
uniprot id: A0A1X4GT88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

146922:HEP81 RS12830
gene id: 146922:HEP81_RS12830
uniprot id: A0A7H1PXX6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

146922:HEP81 RS32435
gene id: 146922:HEP81_RS32435
uniprot id: A0A7H1Q8X4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

146922:HEP81 RS18850
gene id: 146922:HEP81_RS18850
uniprot id: A0A1X4GS61
names: Similarity
messages: Belongs to the LOR family.

146922:HEP81 RS34950
gene id: 146922:HEP81_RS34950
uniprot id: A0A3R8SG42
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS25965
gene id: 146922:HEP81_RS25965
uniprot id: A0A7H1Q5A3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

146922:HEP81 RS15550
gene id: 146922:HEP81_RS15550
uniprot id: A0A7H1PZG3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

146922:HEP81 RS33250
gene id: 146922:HEP81_RS33250
uniprot id: A0A7H1Q9E1
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

146922:HEP81 RS25415
gene id: 146922:HEP81_RS25415
uniprot id: A0A7H1Q4Z6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

146922:HEP81 RS32745
gene id: 146922:HEP81_RS32745
uniprot id: A0A426RZ74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

146922:HEP81 RS20405
gene id: 146922:HEP81_RS20405
uniprot id: A0A426S202
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

146922:HEP81 RS34765
gene id: 146922:HEP81_RS34765
uniprot id: A0A7H1QA98
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

146922:HEP81 RS37550
gene id: 146922:HEP81_RS37550
uniprot id: A0A7H1QBV2
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS00855
gene id: 146922:HEP81_RS00855
uniprot id: A0A7H1PR26
names: Similarity
messages: Belongs to the AAA ATPase family.

146922:HEP81 RS22220
gene id: 146922:HEP81_RS22220
uniprot id: A0A7H1Q370
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS19270
gene id: 146922:HEP81_RS19270
uniprot id: A0A1X4H101
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS10370
gene id: 146922:HEP81_RS10370
uniprot id: A0A7H1PWJ1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS01940
gene id: 146922:HEP81_RS01940
uniprot id: A0A7H1PRP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

146922:HEP81 RS29425
gene id: 146922:HEP81_RS29425
uniprot id: A0A3R8SH28
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS30730
gene id: 146922:HEP81_RS30730
uniprot id: A0A7H1Q7Z4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

146922:HEP81 RS16095
gene id: 146922:HEP81_RS16095
uniprot id: A0A1X4GTK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

146922:HEP81 RS20210
gene id: 146922:HEP81_RS20210
uniprot id: A0A7H1Q222
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

146922:HEP81 RS15350
gene id: 146922:HEP81_RS15350
uniprot id: A0A7H1PZC3
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

146922:HEP81 RS25045
gene id: 146922:HEP81_RS25045
uniprot id: A0A7H1Q4S4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS22300
gene id: 146922:HEP81_RS22300
uniprot id: A0A7H1Q386
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS12060
gene id: 146922:HEP81_RS12060
uniprot id: A0A1X4GVI5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

146922:HEP81 RS16115
gene id: 146922:HEP81_RS16115
uniprot id: A0A1X4GTT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

146922:HEP81 RS04965
gene id: 146922:HEP81_RS04965
uniprot id: A0A7H1PTF1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

146922:HEP81 RS35105
gene id: 146922:HEP81_RS35105
uniprot id: A0A7H1QAG6
names: Similarity
messages: Belongs to the peptidase M1 family.

146922:HEP81 RS22120
gene id: 146922:HEP81_RS22120
uniprot id: A0A3R8WR44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

146922:HEP81 RS20635
gene id: 146922:HEP81_RS20635
uniprot id: A0A1X4H0W4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS23975
gene id: 146922:HEP81_RS23975
uniprot id: A0A3R8QBB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS22595
gene id: 146922:HEP81_RS22595
uniprot id: A0A7H1Q3E6
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

146922:HEP81 RS38685
gene id: 146922:HEP81_RS38685
uniprot id: A0A7H1QCG9
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

146922:HEP81 RS22070
gene id: 146922:HEP81_RS22070
uniprot id: A0A3R8QEP3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

146922:HEP81 RS21520
gene id: 146922:HEP81_RS21520
uniprot id: A0A7H1Q2S9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS07300
gene id: 146922:HEP81_RS07300
uniprot id: A0A7H1PUR7
names: Similarity
messages: Belongs to the CutA family.

146922:HEP81 RS03360
gene id: 146922:HEP81_RS03360
uniprot id: A0A7H1PSI0
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

146922:HEP81 RS03660
gene id: 146922:HEP81_RS03660
uniprot id: A0A7H1PSP0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS09325
gene id: 146922:HEP81_RS09325
uniprot id: A0A7H1PVY3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS19265
gene id: 146922:HEP81_RS19265
uniprot id: A0A3R8QIZ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

146922:HEP81 RS25345
gene id: 146922:HEP81_RS25345
uniprot id: A0A426S5Z7
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

146922:HEP81 RS08225
gene id: 146922:HEP81_RS08225
uniprot id: A0A7H1PVB3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

146922:HEP81 RS25690
gene id: 146922:HEP81_RS25690
uniprot id: A0A7H1Q549
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

146922:HEP81 RS20640
gene id: 146922:HEP81_RS20640
uniprot id: A0A3R8QEC6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS21155
gene id: 146922:HEP81_RS21155
uniprot id: A0A7H1Q2K6
names: Similarity
messages: Belongs to the CutC family.

146922:HEP81 RS08995
gene id: 146922:HEP81_RS08995
uniprot id: A0A7H1PVR8
names: Similarity
messages: Belongs to the catalase family.

146922:HEP81 RS29555
gene id: 146922:HEP81_RS29555
uniprot id: A0A7H1Q7B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

146922:HEP81 RS24365
gene id: 146922:HEP81_RS24365
uniprot id: A0A3R8QG01
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

146922:HEP81 RS15975
gene id: 146922:HEP81_RS15975
uniprot id: A0A7H1PZP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

146922:HEP81 RS24225
gene id: 146922:HEP81_RS24225
uniprot id: A0A426S524
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS39260
gene id: 146922:HEP81_RS39260
uniprot id: A0A7H1QCT2
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

146922:HEP81 RS06755
gene id: 146922:HEP81_RS06755
uniprot id: A0A7H1PUF8
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

146922:HEP81 RS20535
gene id: 146922:HEP81_RS20535
uniprot id: A0A3R8Q986
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS02025
gene id: 146922:HEP81_RS02025
uniprot id: A0A7H1PRQ9
names: Function
names: Similarity
messages: Belongs to the LuxC family.
messages: LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.

146922:HEP81 RS36180
gene id: 146922:HEP81_RS36180
uniprot id: A0A7H1QB31
names: Similarity
messages: Belongs to the universal stress protein A family.

146922:HEP81 RS14785
gene id: 146922:HEP81_RS14785
uniprot id: A0A7H1PZ15
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS25970
gene id: 146922:HEP81_RS25970
uniprot id: A0A3R8RJM6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

146922:HEP81 RS31765
gene id: 146922:HEP81_RS31765
uniprot id: A0A7H1Q8J3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS36660
gene id: 146922:HEP81_RS36660
uniprot id: A0A7H1QBC8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS27065
gene id: 146922:HEP81_RS27065
uniprot id: A0A7H1Q5W8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS08985
gene id: 146922:HEP81_RS08985
uniprot id: A0A7H1PVR6
names: Similarity
messages: Belongs to the hyi family.

146922:HEP81 RS04440
gene id: 146922:HEP81_RS04440
uniprot id: A0A1X4GZ88
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS03860
gene id: 146922:HEP81_RS03860
uniprot id: A0A7H1PST0
names: Similarity
messages: Belongs to the pirin family.

146922:HEP81 RS14985
gene id: 146922:HEP81_RS14985
uniprot id: A0A3R8QDR3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS32790
gene id: 146922:HEP81_RS32790
uniprot id: A0A3R8Q6D9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS32850
gene id: 146922:HEP81_RS32850
uniprot id: A0A7H1Q961
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

146922:HEP81 RS29590
gene id: 146922:HEP81_RS29590
uniprot id: A0A7H1Q7B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

146922:HEP81 RS10350
gene id: 146922:HEP81_RS10350
uniprot id: A0A7H1PWI7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS33170
gene id: 146922:HEP81_RS33170
uniprot id: A0A7H1Q9C5
names: Similarity
messages: Belongs to the asparagine synthetase family.

146922:HEP81 RS17760
gene id: 146922:HEP81_RS17760
uniprot id: A0A7H1Q0P9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS26630
gene id: 146922:HEP81_RS26630
uniprot id: A0A7H1Q5N4
names: Similarity
messages: Belongs to the CdaR family.

146922:HEP81 RS14050
gene id: 146922:HEP81_RS14050
uniprot id: A0A426S3I1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

146922:HEP81 RS17360
gene id: 146922:HEP81_RS17360
uniprot id: A0A7H1Q0G5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS11595
gene id: 146922:HEP81_RS11595
uniprot id: A0A7H1PX84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

146922:HEP81 RS04315
gene id: 146922:HEP81_RS04315
uniprot id: A0A3R8RBB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

146922:HEP81 RS06935
gene id: 146922:HEP81_RS06935
uniprot id: A0A1X4GXN0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS34355
gene id: 146922:HEP81_RS34355
uniprot id: A0A426SCG6
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

146922:HEP81 RS23070
gene id: 146922:HEP81_RS23070
uniprot id: A0A7H1Q3P0
names: Similarity
messages: Belongs to the ParB family.

146922:HEP81 RS06375
gene id: 146922:HEP81_RS06375
uniprot id: A0A7H1PU85
names: Similarity
messages: Belongs to the thioesterase family.

146922:HEP81 RS05855
gene id: 146922:HEP81_RS05855
uniprot id: A0A7H1PTY1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

146922:HEP81 RS32725
gene id: 146922:HEP81_RS32725
uniprot id: A0A1X4H3Z3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

146922:HEP81 RS36535
gene id: 146922:HEP81_RS36535
uniprot id: A0A7H1QBA1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

146922:HEP81 RS09155
gene id: 146922:HEP81_RS09155
uniprot id: A0A7H1PVU9
names: Similarity
messages: Belongs to the TPP enzyme family.

146922:HEP81 RS16065
gene id: 146922:HEP81_RS16065
uniprot id: A0A3R8RHR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

146922:HEP81 RS18955
gene id: 146922:HEP81_RS18955
uniprot id: A0A7H1Q1D9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

146922:HEP81 RS10760
gene id: 146922:HEP81_RS10760
uniprot id: A0A7H1PWS0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

146922:HEP81 RS17735
gene id: 146922:HEP81_RS17735
uniprot id: A0A7H1Q0P4
names: Similarity
messages: Belongs to the asparagine synthetase family.

146922:HEP81 RS29350
gene id: 146922:HEP81_RS29350
uniprot id: A0A426SDZ4
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

146922:HEP81 RS02170
gene id: 146922:HEP81_RS02170
uniprot id: A0A7H1PRT9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS36560
gene id: 146922:HEP81_RS36560
uniprot id: A0A426S8N3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Heterodimer of an alpha and a beta chain.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS39785
gene id: 146922:HEP81_RS39785
uniprot id: A0A7H1QD30
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

146922:HEP81 RS31075
gene id: 146922:HEP81_RS31075
uniprot id: A0A1X4H3B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

146922:HEP81 RS25590
gene id: 146922:HEP81_RS25590
uniprot id: A0A7H1Q531
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

146922:HEP81 RS06040
gene id: 146922:HEP81_RS06040
uniprot id: A0A7H1PU18
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

146922:HEP81 RS25880
gene id: 146922:HEP81_RS25880
uniprot id: A0A7H1Q586
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS06060
gene id: 146922:HEP81_RS06060
uniprot id: A0A7H1PU22
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

146922:HEP81 RS11625
gene id: 146922:HEP81_RS11625
uniprot id: A0A7H1PX90
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

146922:HEP81 RS26610
gene id: 146922:HEP81_RS26610
uniprot id: A0A3R8S6L9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

146922:HEP81 RS38110
gene id: 146922:HEP81_RS38110
uniprot id: A0A7H1QC64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

146922:HEP81 RS26195
gene id: 146922:HEP81_RS26195
uniprot id: A0A7H1Q5E9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

146922:HEP81 RS10415
gene id: 146922:HEP81_RS10415
uniprot id: A0A7H1PWK0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS28500
gene id: 146922:HEP81_RS28500
uniprot id: A0A426SE32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS06250
gene id: 146922:HEP81_RS06250
uniprot id: A0A7H1PU60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS00675
gene id: 146922:HEP81_RS00675
uniprot id: A0A7H1PQY9
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS17410
gene id: 146922:HEP81_RS17410
uniprot id: A0A1X4GT41
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS06775
gene id: 146922:HEP81_RS06775
uniprot id: A0A7H1PUG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

146922:HEP81 RS28270
gene id: 146922:HEP81_RS28270
uniprot id: A0A3R8S637
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS14925
gene id: 146922:HEP81_RS14925
uniprot id: A0A7H1PZ40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

146922:HEP81 RS28325
gene id: 146922:HEP81_RS28325
uniprot id: A0A7H1Q6L5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

146922:HEP81 RS01895
gene id: 146922:HEP81_RS01895
uniprot id: A0A3R8QCI4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS12270
gene id: 146922:HEP81_RS12270
uniprot id: A0A7H1PXL8
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

146922:HEP81 RS12015
gene id: 146922:HEP81_RS12015
uniprot id: A0A426S0M1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

146922:HEP81 RS04150
gene id: 146922:HEP81_RS04150
uniprot id: A0A7H1PSY6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

146922:HEP81 RS09720
gene id: 146922:HEP81_RS09720
uniprot id: A0A3R8QK82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS22635
gene id: 146922:HEP81_RS22635
uniprot id: A0A7H1Q3F4
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS32870
gene id: 146922:HEP81_RS32870
uniprot id: A0A7H1Q965
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS17215
gene id: 146922:HEP81_RS17215
uniprot id: A0A1X4GT04
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

146922:HEP81 RS13190
gene id: 146922:HEP81_RS13190
uniprot id: A0A1X4GUZ5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

146922:HEP81 RS10620
gene id: 146922:HEP81_RS10620
uniprot id: A0A7H1PWP1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS31600
gene id: 146922:HEP81_RS31600
uniprot id: A0A7H1Q8G0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS11735
gene id: 146922:HEP81_RS11735
uniprot id: A0A7H1PXB1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS04445
gene id: 146922:HEP81_RS04445
uniprot id: A0A7H1PT47
names: Similarity
messages: Belongs to the CapA family.

146922:HEP81 RS08490
gene id: 146922:HEP81_RS08490
uniprot id: A0A7H1PVG6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS13805
gene id: 146922:HEP81_RS13805
uniprot id: A0A1X4GUM7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

146922:HEP81 RS34340
gene id: 146922:HEP81_RS34340
uniprot id: A0A3R8QL05
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS30045
gene id: 146922:HEP81_RS30045
uniprot id: A0A7H1Q7K6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

146922:HEP81 RS11405
gene id: 146922:HEP81_RS11405
uniprot id: A0A7H1PX50
names: Similarity
messages: Belongs to the Dps family.

146922:HEP81 RS20070
gene id: 146922:HEP81_RS20070
uniprot id: A0A7H1Q200
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

146922:HEP81 RS08360
gene id: 146922:HEP81_RS08360
uniprot id: A0A7H1PVE0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS30405
gene id: 146922:HEP81_RS30405
uniprot id: A0A7H1Q7S8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

146922:HEP81 RS29640
gene id: 146922:HEP81_RS29640
uniprot id: A0A7H1Q7C7
names: Similarity
messages: Belongs to the peptidase U62 family.

146922:HEP81 RS11365
gene id: 146922:HEP81_RS11365
uniprot id: A0A7H1PX42
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

146922:HEP81 RS38245
gene id: 146922:HEP81_RS38245
uniprot id: A0A7H1QC88
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

146922:HEP81 RS13320
gene id: 146922:HEP81_RS13320
uniprot id: A0A3R8Q9U0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

146922:HEP81 RS32980
gene id: 146922:HEP81_RS32980
uniprot id: A0A426RZK2
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

146922:HEP81 RS33875
gene id: 146922:HEP81_RS33875
uniprot id: A0A7H1Q9R8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

146922:HEP81 RS08820
gene id: 146922:HEP81_RS08820
uniprot id: A0A7H1PVN2
names: Similarity
messages: Belongs to the asparagine synthetase family.

146922:HEP81 RS09200
gene id: 146922:HEP81_RS09200
uniprot id: A0A7H1PVV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

146922:HEP81 RS24980
gene id: 146922:HEP81_RS24980
uniprot id: A0A7H1Q4R0
names: Similarity
messages: Belongs to the TPP enzyme family.

146922:HEP81 RS27230
gene id: 146922:HEP81_RS27230
uniprot id: A0A7H1Q5Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

146922:HEP81 RS11340
gene id: 146922:HEP81_RS11340
uniprot id: A0A7H1PX37
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

146922:HEP81 RS32405
gene id: 146922:HEP81_RS32405
uniprot id: A0A426RZ39
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

146922:HEP81 RS11120
gene id: 146922:HEP81_RS11120
uniprot id: A0A7H1PWZ3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

146922:HEP81 RS36395
gene id: 146922:HEP81_RS36395
uniprot id: A0A7H1QB74
names: Similarity
messages: Belongs to the YciI family.

146922:HEP81 RS29855
gene id: 146922:HEP81_RS29855
uniprot id: A0A7H1Q7G8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS31905
gene id: 146922:HEP81_RS31905
uniprot id: A0A1X4H3R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

146922:HEP81 RS00230
gene id: 146922:HEP81_RS00230
uniprot id: A0A7H1PQP9
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS04125
gene id: 146922:HEP81_RS04125
uniprot id: A0A7H1PSY1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

146922:HEP81 RS30030
gene id: 146922:HEP81_RS30030
uniprot id: A0A426S6X4
names: Similarity
messages: Belongs to the peptidase S1 family.

146922:HEP81 RS09655
gene id: 146922:HEP81_RS09655
uniprot id: A0A7H1PW48
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

146922:HEP81 RS31375
gene id: 146922:HEP81_RS31375
uniprot id: A0A1X4H3J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

146922:HEP81 RS26045
gene id: 146922:HEP81_RS26045
uniprot id: A0A7H1Q5B9
names: Similarity
messages: Belongs to the peptidase S66 family.

146922:HEP81 RS23650
gene id: 146922:HEP81_RS23650
uniprot id: A0A7H1Q407
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

146922:HEP81 RS38160
gene id: 146922:HEP81_RS38160
uniprot id: A0A7H1QC74
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS06010
gene id: 146922:HEP81_RS06010
uniprot id: A0A7H1PU12
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

146922:HEP81 RS25000
gene id: 146922:HEP81_RS25000
uniprot id: A0A7H1Q4R5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS31570
gene id: 146922:HEP81_RS31570
uniprot id: A0A7H1Q8F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

146922:HEP81 RS36960
gene id: 146922:HEP81_RS36960
uniprot id: A0A7H1QBI8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS38520
gene id: 146922:HEP81_RS38520
uniprot id: A0A7H1QCE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS20110
gene id: 146922:HEP81_RS20110
uniprot id: A0A7H1Q208
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homodimer.

146922:HEP81 RS22520
gene id: 146922:HEP81_RS22520
uniprot id: A0A1X4GQ66
names: Similarity
messages: Belongs to the ABC transporter superfamily.

146922:HEP81 RS13335
gene id: 146922:HEP81_RS13335
uniprot id: A0A7H1PY77
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS34450
gene id: 146922:HEP81_RS34450
uniprot id: A0A7H1QA35
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

146922:HEP81 RS28320
gene id: 146922:HEP81_RS28320
uniprot id: A0A7H1Q6L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

146922:HEP81 RS14790
gene id: 146922:HEP81_RS14790
uniprot id: A0A7H1PZ16
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS09740
gene id: 146922:HEP81_RS09740
uniprot id: A0A426SBB6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

146922:HEP81 RS14700
gene id: 146922:HEP81_RS14700
uniprot id: A0A3R8RZI3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

146922:HEP81 RS11600
gene id: 146922:HEP81_RS11600
uniprot id: A0A7H1PX85
names: Similarity
messages: Belongs to the EccE family.

146922:HEP81 RS35685
gene id: 146922:HEP81_RS35685
uniprot id: A0A7H1QAT1
names: Similarity
messages: Belongs to the HypD family.

146922:HEP81 RS27415
gene id: 146922:HEP81_RS27415
uniprot id: A0A3R8RJB4
names: Similarity
messages: Belongs to the CutA family.

146922:HEP81 RS11125
gene id: 146922:HEP81_RS11125
uniprot id: A0A7H1PWZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

146922:HEP81 RS30840
gene id: 146922:HEP81_RS30840
uniprot id: A0A1X4H3R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

146922:HEP81 RS21300
gene id: 146922:HEP81_RS21300
uniprot id: A0A7H1Q2N5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

146922:HEP81 RS00635
gene id: 146922:HEP81_RS00635
uniprot id: A0A7H1PQY2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS15830
gene id: 146922:HEP81_RS15830
uniprot id: A0A1X4GTR3
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

146922:HEP81 RS13930
gene id: 146922:HEP81_RS13930
uniprot id: A0A7H1PYJ5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

146922:HEP81 RS31550
gene id: 146922:HEP81_RS31550
uniprot id: A0A7H1Q8F0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS22295
gene id: 146922:HEP81_RS22295
uniprot id: A0A7H1Q385
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS04890
gene id: 146922:HEP81_RS04890
uniprot id: A0A7H1PTD6
names: Similarity
messages: Belongs to the PrpD family.

146922:HEP81 RS16610
gene id: 146922:HEP81_RS16610
uniprot id: A0A7H1Q022
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS16320
gene id: 146922:HEP81_RS16320
uniprot id: A0A1X4GTE1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

146922:HEP81 RS32735
gene id: 146922:HEP81_RS32735
uniprot id: A0A7H1Q938
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

146922:HEP81 RS39470
gene id: 146922:HEP81_RS39470
uniprot id: A0A7H1QCW8
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

146922:HEP81 RS28300
gene id: 146922:HEP81_RS28300
uniprot id: A0A7H1Q6L0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

146922:HEP81 RS22450
gene id: 146922:HEP81_RS22450
uniprot id: A0A7H1Q3B7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS18825
gene id: 146922:HEP81_RS18825
uniprot id: A0A1X4GS27
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS24870
gene id: 146922:HEP81_RS24870
uniprot id: A0A426S5L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

146922:HEP81 RS11990
gene id: 146922:HEP81_RS11990
uniprot id: A0A1X4GVG1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

146922:HEP81 RS05500
gene id: 146922:HEP81_RS05500
uniprot id: A0A7H1PTR0
names: Similarity
messages: Belongs to the glutamine synthetase family.

146922:HEP81 RS30425
gene id: 146922:HEP81_RS30425
uniprot id: A0A426S6Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

146922:HEP81 RS35180
gene id: 146922:HEP81_RS35180
uniprot id: A0A1X4H5S6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS37585
gene id: 146922:HEP81_RS37585
uniprot id: A0A7H1QBV9
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS12700
gene id: 146922:HEP81_RS12700
uniprot id: A0A7H1PXV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS22400
gene id: 146922:HEP81_RS22400
uniprot id: A0A7H1Q3A7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

146922:HEP81 RS06120
gene id: 146922:HEP81_RS06120
uniprot id: A0A7H1PU34
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

146922:HEP81 RS27815
gene id: 146922:HEP81_RS27815
uniprot id: A0A7H1Q6B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

146922:HEP81 RS18805
gene id: 146922:HEP81_RS18805
uniprot id: A0A7H1Q1A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS08370
gene id: 146922:HEP81_RS08370
uniprot id: A0A7H1PVE2
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS16265
gene id: 146922:HEP81_RS16265
uniprot id: A0A1X4GTP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

146922:HEP81 RS32765
gene id: 146922:HEP81_RS32765
uniprot id: A0A7H1Q944
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS02885
gene id: 146922:HEP81_RS02885
uniprot id: A0A7H1PS84
names: Similarity
messages: Belongs to the AHA1 family.

146922:HEP81 RS05050
gene id: 146922:HEP81_RS05050
uniprot id: A0A7H1PTG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

146922:HEP81 RS10525
gene id: 146922:HEP81_RS10525
uniprot id: A0A7H1PWM2
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

146922:HEP81 RS28715
gene id: 146922:HEP81_RS28715
uniprot id: A0A3R8RQI9
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

146922:HEP81 RS31210
gene id: 146922:HEP81_RS31210
uniprot id: A0A3R8QAL2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

146922:HEP81 RS36495
gene id: 146922:HEP81_RS36495
uniprot id: A0A7H1QB94
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS25400
gene id: 146922:HEP81_RS25400
uniprot id: A0A7H1Q4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS26865
gene id: 146922:HEP81_RS26865
uniprot id: A0A7H1Q5S9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS29105
gene id: 146922:HEP81_RS29105
uniprot id: A0A3R8RQF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

146922:HEP81 RS21830
gene id: 146922:HEP81_RS21830
uniprot id: A0A426S2P9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS18135
gene id: 146922:HEP81_RS18135
uniprot id: A0A426SAT5
names: Similarity
messages: Belongs to the CsoR family.

146922:HEP81 RS32630
gene id: 146922:HEP81_RS32630
uniprot id: A0A3R8QCT7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS18560
gene id: 146922:HEP81_RS18560
uniprot id: A0A7H1Q159
names: Similarity
messages: Belongs to the FPG family.

146922:HEP81 RS16850
gene id: 146922:HEP81_RS16850
uniprot id: A0A1X4GT12
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS18295
gene id: 146922:HEP81_RS18295
uniprot id: A0A1X4GS57
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS34785
gene id: 146922:HEP81_RS34785
uniprot id: A0A7H1QAA2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

146922:HEP81 RS13355
gene id: 146922:HEP81_RS13355
uniprot id: A0A7H1PY81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

146922:HEP81 RS16270
gene id: 146922:HEP81_RS16270
uniprot id: A0A426S1M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

146922:HEP81 RS30240
gene id: 146922:HEP81_RS30240
uniprot id: A0A7H1Q7P6
names: Similarity
messages: Belongs to the peptidase S45 family.

146922:HEP81 RS05980
gene id: 146922:HEP81_RS05980
uniprot id: A0A7H1PU06
names: Similarity
messages: Belongs to the YciI family.

146922:HEP81 RS03820
gene id: 146922:HEP81_RS03820
uniprot id: A0A1X4GZN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS02160
gene id: 146922:HEP81_RS02160
uniprot id: A0A7H1PRT7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS37470
gene id: 146922:HEP81_RS37470
uniprot id: A0A7H1QBT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS19505
gene id: 146922:HEP81_RS19505
uniprot id: A0A7H1Q1P7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

146922:HEP81 RS16715
gene id: 146922:HEP81_RS16715
uniprot id: A0A426RW97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

146922:HEP81 RS04540
gene id: 146922:HEP81_RS04540
uniprot id: A0A3R8R8P0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

146922:HEP81 RS13210
gene id: 146922:HEP81_RS13210
uniprot id: A0A7H1PY52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS20395
gene id: 146922:HEP81_RS20395
uniprot id: A0A7H1Q255
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

146922:HEP81 RS03000
gene id: 146922:HEP81_RS03000
uniprot id: A0A3R8S7T9
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

146922:HEP81 RS13780
gene id: 146922:HEP81_RS13780
uniprot id: A0A3R8WRI4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS37105
gene id: 146922:HEP81_RS37105
uniprot id: A0A7H1QBL5
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

146922:HEP81 RS37005
gene id: 146922:HEP81_RS37005
uniprot id: A0A7H1QBJ7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

146922:HEP81 RS39595
gene id: 146922:HEP81_RS39595
uniprot id: A0A7H1QCZ2
names: Similarity
messages: Belongs to the thioesterase family.

146922:HEP81 RS22280
gene id: 146922:HEP81_RS22280
uniprot id: A0A3R8WN83
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS31480
gene id: 146922:HEP81_RS31480
uniprot id: A0A7H1Q8D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS22630
gene id: 146922:HEP81_RS22630
uniprot id: A0A7H1Q3F3
names: Similarity
messages: Belongs to the CFA/CMAS family.

146922:HEP81 RS34005
gene id: 146922:HEP81_RS34005
uniprot id: A0A7H1Q9U3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

146922:HEP81 RS13595
gene id: 146922:HEP81_RS13595
uniprot id: A0A1X4GUW7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

146922:HEP81 RS38390
gene id: 146922:HEP81_RS38390
uniprot id: A0A7H1QCB7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS36115
gene id: 146922:HEP81_RS36115
uniprot id: A0A426S8U3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS28565
gene id: 146922:HEP81_RS28565
uniprot id: A0A3R8QFQ0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

146922:HEP81 RS26685
gene id: 146922:HEP81_RS26685
uniprot id: A0A7H1Q5P5
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

146922:HEP81 RS05650
gene id: 146922:HEP81_RS05650
uniprot id: A0A7H1PTT9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

146922:HEP81 RS18965
gene id: 146922:HEP81_RS18965
uniprot id: A0A7H1Q1E1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

146922:HEP81 RS12115
gene id: 146922:HEP81_RS12115
uniprot id: A0A7H1PXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

146922:HEP81 RS37710
gene id: 146922:HEP81_RS37710
uniprot id: A0A7H1QBY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS39455
gene id: 146922:HEP81_RS39455
uniprot id: A0A7H1QCW5
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

146922:HEP81 RS19120
gene id: 146922:HEP81_RS19120
uniprot id: A0A7H1Q1H3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS18165
gene id: 146922:HEP81_RS18165
uniprot id: A0A7H1Q0X7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS06645
gene id: 146922:HEP81_RS06645
uniprot id: A0A7H1PUD6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

146922:HEP81 RS24395
gene id: 146922:HEP81_RS24395
uniprot id: A0A3R8RE47
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

146922:HEP81 RS25720
gene id: 146922:HEP81_RS25720
uniprot id: A0A3R8QGF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

146922:HEP81 RS34570
gene id: 146922:HEP81_RS34570
uniprot id: A0A7H1QA59
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS13910
gene id: 146922:HEP81_RS13910
uniprot id: A0A1X4GUK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS19565
gene id: 146922:HEP81_RS19565
uniprot id: A0A7H1Q1Q9
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

146922:HEP81 RS10530
gene id: 146922:HEP81_RS10530
uniprot id: A0A7H1PWM3
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

146922:HEP81 RS16625
gene id: 146922:HEP81_RS16625
uniprot id: A0A1X4GTD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS37120
gene id: 146922:HEP81_RS37120
uniprot id: A0A7H1QBL8
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

146922:HEP81 RS14675
gene id: 146922:HEP81_RS14675
uniprot id: A0A7H1PYZ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

146922:HEP81 RS24090
gene id: 146922:HEP81_RS24090
uniprot id: A0A7H1Q491
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

146922:HEP81 RS35670
gene id: 146922:HEP81_RS35670
uniprot id: A0A7H1QAS8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

146922:HEP81 RS31585
gene id: 146922:HEP81_RS31585
uniprot id: A0A1X4H3V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

146922:HEP81 RS34540
gene id: 146922:HEP81_RS34540
uniprot id: A0A7H1QA53
names: Similarity
messages: Belongs to the EccD/Snm4 family.

146922:HEP81 RS27445
gene id: 146922:HEP81_RS27445
uniprot id: A0A7H1Q642
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS31965
gene id: 146922:HEP81_RS31965
uniprot id: A0A7H1Q8N0
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

146922:HEP81 RS12455
gene id: 146922:HEP81_RS12455
uniprot id: A0A7H1PXQ0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS16480
gene id: 146922:HEP81_RS16480
uniprot id: A0A7H1PZZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS12480
gene id: 146922:HEP81_RS12480
uniprot id: A0A7H1PXQ5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

146922:HEP81 RS33135
gene id: 146922:HEP81_RS33135
uniprot id: A0A7H1Q9B8
names: Similarity
messages: Belongs to the thioesterase family.

146922:HEP81 RS24730
gene id: 146922:HEP81_RS24730
uniprot id: A0A7H1Q4L3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

146922:HEP81 RS01410
gene id: 146922:HEP81_RS01410
uniprot id: A0A7H1PRD6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS21350
gene id: 146922:HEP81_RS21350
uniprot id: A0A1X4GQM0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS30985
gene id: 146922:HEP81_RS30985
uniprot id: A0A7H1Q844
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

146922:HEP81 RS13340
gene id: 146922:HEP81_RS13340
uniprot id: A0A3R8QEY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

146922:HEP81 RS09285
gene id: 146922:HEP81_RS09285
uniprot id: A0A7H1PVX5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS15475
gene id: 146922:HEP81_RS15475
uniprot id: A0A426S1A9
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS00080
gene id: 146922:HEP81_RS00080
uniprot id: A0A7H1PQM4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

146922:HEP81 RS19335
gene id: 146922:HEP81_RS19335
uniprot id: A0A7H1Q1L3
names: Similarity
messages: Belongs to the ParB family.

146922:HEP81 RS35500
gene id: 146922:HEP81_RS35500
uniprot id: A0A7H1QAP6
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

146922:HEP81 RS05070
gene id: 146922:HEP81_RS05070
uniprot id: A0A7H1PTH3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

146922:HEP81 RS17755
gene id: 146922:HEP81_RS17755
uniprot id: A0A7H1Q0P8
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS15615
gene id: 146922:HEP81_RS15615
uniprot id: A0A1X4GTQ1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

146922:HEP81 RS10860
gene id: 146922:HEP81_RS10860
uniprot id: A0A7H1PWU1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

146922:HEP81 RS03245
gene id: 146922:HEP81_RS03245
uniprot id: A0A7H1PSF7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS34010
gene id: 146922:HEP81_RS34010
uniprot id: A0A7H1Q9U4
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS08510
gene id: 146922:HEP81_RS08510
uniprot id: A0A7H1PVH0
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS23790
gene id: 146922:HEP81_RS23790
uniprot id: A0A3R8Q5A7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS26135
gene id: 146922:HEP81_RS26135
uniprot id: A0A7H1Q5D7
names: Similarity
messages: Belongs to the DapA family.

146922:HEP81 RS25475
gene id: 146922:HEP81_RS25475
uniprot id: A0A7H1Q508
names: Similarity
messages: Belongs to the peptidase M1 family.

146922:HEP81 RS10560
gene id: 146922:HEP81_RS10560
uniprot id: A0A7H1PWM9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS00655
gene id: 146922:HEP81_RS00655
uniprot id: A0A7H1PQY5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS21080
gene id: 146922:HEP81_RS21080
uniprot id: A0A7H1Q2J1
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

146922:HEP81 RS35370
gene id: 146922:HEP81_RS35370
uniprot id: A0A3R8S2X9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS04075
gene id: 146922:HEP81_RS04075
uniprot id: A0A3R8RWZ5
names: Similarity
messages: Belongs to the peptidase S51 family.

146922:HEP81 RS08800
gene id: 146922:HEP81_RS08800
uniprot id: A0A7H1PVM8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

146922:HEP81 RS36150
gene id: 146922:HEP81_RS36150
uniprot id: A0A7H1QB26
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

146922:HEP81 RS16430
gene id: 146922:HEP81_RS16430
uniprot id: A0A426S1N2
names: Similarity
messages: Belongs to the UPF0234 family.

146922:HEP81 RS23680
gene id: 146922:HEP81_RS23680
uniprot id: A0A3R8R7A2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

146922:HEP81 RS18780
gene id: 146922:HEP81_RS18780
uniprot id: A0A7H1Q1A3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS04155
gene id: 146922:HEP81_RS04155
uniprot id: A0A7H1PSY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

146922:HEP81 RS04160
gene id: 146922:HEP81_RS04160
uniprot id: A0A7H1PSY8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

146922:HEP81 RS24330
gene id: 146922:HEP81_RS24330
uniprot id: A0A7H1Q4D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

146922:HEP81 RS28985
gene id: 146922:HEP81_RS28985
uniprot id: A0A7H1Q6Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS21425
gene id: 146922:HEP81_RS21425
uniprot id: A0A3R8WQY8
names: Similarity
messages: Belongs to the citrate synthase family.

146922:HEP81 RS25815
gene id: 146922:HEP81_RS25815
uniprot id: A0A426SFS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

146922:HEP81 RS06700
gene id: 146922:HEP81_RS06700
uniprot id: A0A7H1PUE7
names: Similarity
messages: Belongs to the TPP enzyme family.

146922:HEP81 RS33655
gene id: 146922:HEP81_RS33655
uniprot id: A0A7H1Q9M3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

146922:HEP81 RS29040
gene id: 146922:HEP81_RS29040
uniprot id: A0A3R8RHC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

146922:HEP81 RS10140
gene id: 146922:HEP81_RS10140
uniprot id: A0A7H1PWE5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

146922:HEP81 RS09225
gene id: 146922:HEP81_RS09225
uniprot id: A0A7H1PVW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

146922:HEP81 RS06710
gene id: 146922:HEP81_RS06710
uniprot id: A0A3R8Q9A9
names: Similarity
messages: Belongs to the peptidase C56 family.

146922:HEP81 RS17630
gene id: 146922:HEP81_RS17630
uniprot id: A0A7H1Q0M1
names: Similarity
messages: Belongs to the UPF0145 family.

146922:HEP81 RS26980
gene id: 146922:HEP81_RS26980
uniprot id: A0A7H1Q5V2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

146922:HEP81 RS28405
gene id: 146922:HEP81_RS28405
uniprot id: A0A3R8SHC0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS37825
gene id: 146922:HEP81_RS37825
uniprot id: A0A7H1QC07
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS30825
gene id: 146922:HEP81_RS30825
uniprot id: A0A7H1Q812
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

146922:HEP81 RS23780
gene id: 146922:HEP81_RS23780
uniprot id: A0A7H1Q433
names: Similarity
messages: Belongs to the PGI/PMI family.

146922:HEP81 RS25170
gene id: 146922:HEP81_RS25170
uniprot id: A0A7H1Q4U9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

146922:HEP81 RS13815
gene id: 146922:HEP81_RS13815
uniprot id: A0A7H1PYH1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS11485
gene id: 146922:HEP81_RS11485
uniprot id: A0A7H1PX62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

146922:HEP81 RS12200
gene id: 146922:HEP81_RS12200
uniprot id: A0A7H1PXK4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

146922:HEP81 RS29460
gene id: 146922:HEP81_RS29460
uniprot id: A0A7H1Q792
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

146922:HEP81 RS12785
gene id: 146922:HEP81_RS12785
uniprot id: A0A1X4GUZ8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

146922:HEP81 RS01550
gene id: 146922:HEP81_RS01550
uniprot id: A0A7H1PRG3
names: Similarity
messages: Belongs to the DapA family.

146922:HEP81 RS09270
gene id: 146922:HEP81_RS09270
uniprot id: A0A7H1PVX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

146922:HEP81 RS26840
gene id: 146922:HEP81_RS26840
uniprot id: A0A7H1Q5S4
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS26520
gene id: 146922:HEP81_RS26520
uniprot id: A0A7H1Q5L1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS13945
gene id: 146922:HEP81_RS13945
uniprot id: A0A3R8RZA0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS12145
gene id: 146922:HEP81_RS12145
uniprot id: A0A426S0H6
names: Similarity
messages: Belongs to the acylphosphatase family.

146922:HEP81 RS02325
gene id: 146922:HEP81_RS02325
uniprot id: A0A7H1PRX2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

146922:HEP81 RS13085
gene id: 146922:HEP81_RS13085
uniprot id: A0A1X4GV16
names: Similarity
messages: Belongs to the UPF0045 family.

146922:HEP81 RS18220
gene id: 146922:HEP81_RS18220
uniprot id: A0A7H1Q0Y8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

146922:HEP81 RS31685
gene id: 146922:HEP81_RS31685
uniprot id: A0A7H1Q8H7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS27575
gene id: 146922:HEP81_RS27575
uniprot id: A0A7H1Q666
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

146922:HEP81 RS18190
gene id: 146922:HEP81_RS18190
uniprot id: A0A1X4GSJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

146922:HEP81 RS24950
gene id: 146922:HEP81_RS24950
uniprot id: A0A1X4H0Z5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS18675
gene id: 146922:HEP81_RS18675
uniprot id: A0A7H1Q182
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS22355
gene id: 146922:HEP81_RS22355
uniprot id: A0A1X4GQK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

146922:HEP81 RS37045
gene id: 146922:HEP81_RS37045
uniprot id: A0A1X4H6V6
names: Subcellular Location Annotation
messages: Cytoplasm

146922:HEP81 RS19640
gene id: 146922:HEP81_RS19640
uniprot id: A0A3R8WVC9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS15245
gene id: 146922:HEP81_RS15245
uniprot id: A0A7H1PZA3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS35470
gene id: 146922:HEP81_RS35470
uniprot id: A0A7H1QAP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

146922:HEP81 RS12780
gene id: 146922:HEP81_RS12780
uniprot id: A0A1X4GVC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS07095
gene id: 146922:HEP81_RS07095
uniprot id: A0A7H1PUM5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS21065
gene id: 146922:HEP81_RS21065
uniprot id: A0A7H1Q2I8
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

146922:HEP81 RS16640
gene id: 146922:HEP81_RS16640
uniprot id: A0A7H1Q028
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

146922:HEP81 RS21280
gene id: 146922:HEP81_RS21280
uniprot id: A0A1X4GQX7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS15160
gene id: 146922:HEP81_RS15160
uniprot id: A0A7H1PZ86
names: Similarity
messages: Belongs to the phosphohexose mutase family.

146922:HEP81 RS30820
gene id: 146922:HEP81_RS30820
uniprot id: A0A7H1Q811
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

146922:HEP81 RS38770
gene id: 146922:HEP81_RS38770
uniprot id: A0A7H1QCI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

146922:HEP81 RS10335
gene id: 146922:HEP81_RS10335
uniprot id: A0A7H1PWI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

146922:HEP81 RS30420
gene id: 146922:HEP81_RS30420
uniprot id: A0A7H1Q7T1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS01890
gene id: 146922:HEP81_RS01890
uniprot id: A0A7H1PRN2
names: Similarity
messages: Belongs to the ribulokinase family.

146922:HEP81 RS21125
gene id: 146922:HEP81_RS21125
uniprot id: A0A426S279
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS04720
gene id: 146922:HEP81_RS04720
uniprot id: A0A1X4GYX3
names: Subcellular Location Annotation
messages: Cytoplasm

146922:HEP81 RS39020
gene id: 146922:HEP81_RS39020
uniprot id: A0A7H1PQP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

146922:HEP81 RS27210
gene id: 146922:HEP81_RS27210
uniprot id: A0A3R8SHN1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS11040
gene id: 146922:HEP81_RS11040
uniprot id: A0A3R8QE36
names: Similarity
messages: Belongs to the Nudix hydrolase family.

146922:HEP81 RS35785
gene id: 146922:HEP81_RS35785
uniprot id: A0A7H1QAV1
names: Similarity
messages: Belongs to the universal stress protein A family.

146922:HEP81 RS30830
gene id: 146922:HEP81_RS30830
uniprot id: A0A7H1Q813
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

146922:HEP81 RS16460
gene id: 146922:HEP81_RS16460
uniprot id: A0A7H1PZZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

146922:HEP81 RS18980
gene id: 146922:HEP81_RS18980
uniprot id: A0A3R8SEP4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS12875
gene id: 146922:HEP81_RS12875
uniprot id: A0A7H1PXY5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS34365
gene id: 146922:HEP81_RS34365
uniprot id: A0A7H1QA17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

146922:HEP81 RS12450
gene id: 146922:HEP81_RS12450
uniprot id: A0A7H1PXP9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

146922:HEP81 RS04870
gene id: 146922:HEP81_RS04870
uniprot id: A0A7H1PTD2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS15285
gene id: 146922:HEP81_RS15285
uniprot id: A0A426S145
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS12280
gene id: 146922:HEP81_RS12280
uniprot id: A0A7H1PXM0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

146922:HEP81 RS09235
gene id: 146922:HEP81_RS09235
uniprot id: A0A7H1PVW5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS31580
gene id: 146922:HEP81_RS31580
uniprot id: A0A3R8QGM7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

146922:HEP81 RS24895
gene id: 146922:HEP81_RS24895
uniprot id: A0A7H1Q4P3
names: Similarity
messages: Belongs to the IucA/IucC family.

146922:HEP81 RS39490
gene id: 146922:HEP81_RS39490
uniprot id: A0A7H1QCX1
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

146922:HEP81 RS39355
gene id: 146922:HEP81_RS39355
uniprot id: A0A7H1QCV1
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS01290
gene id: 146922:HEP81_RS01290
uniprot id: A0A7H1PRB2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

146922:HEP81 RS17570
gene id: 146922:HEP81_RS17570
uniprot id: A0A1X4GSR4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

146922:HEP81 RS20170
gene id: 146922:HEP81_RS20170
uniprot id: A0A1X4GRP6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS15635
gene id: 146922:HEP81_RS15635
uniprot id: A0A7H1PZI0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS11655
gene id: 146922:HEP81_RS11655
uniprot id: A0A7H1PX96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

146922:HEP81 RS14885
gene id: 146922:HEP81_RS14885
uniprot id: A0A7H1PZ32
names: Similarity
messages: Belongs to the DSD1 family.

146922:HEP81 RS15025
gene id: 146922:HEP81_RS15025
uniprot id: A0A7H1PZ60
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

146922:HEP81 RS21755
gene id: 146922:HEP81_RS21755
uniprot id: A0A426S2K3
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

146922:HEP81 RS17285
gene id: 146922:HEP81_RS17285
uniprot id: A0A7H1Q0F3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS09585
gene id: 146922:HEP81_RS09585
uniprot id: A0A3R8RFK6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS30480
gene id: 146922:HEP81_RS30480
uniprot id: A0A3R8S182
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

146922:HEP81 RS17540
gene id: 146922:HEP81_RS17540
uniprot id: A0A7H1Q0K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS39600
gene id: 146922:HEP81_RS39600
uniprot id: A0A7H1QCZ3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

146922:HEP81 RS15760
gene id: 146922:HEP81_RS15760
uniprot id: A0A7H1PZK5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

146922:HEP81 RS17405
gene id: 146922:HEP81_RS17405
uniprot id: A0A7H1Q0H4
names: Similarity
messages: Belongs to the Nth/MutY family.

146922:HEP81 RS12445
gene id: 146922:HEP81_RS12445
uniprot id: A0A7H1PXP8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS26355
gene id: 146922:HEP81_RS26355
uniprot id: A0A7H1Q5I1
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

146922:HEP81 RS24045
gene id: 146922:HEP81_RS24045
uniprot id: A0A7H1Q482
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

146922:HEP81 RS26800
gene id: 146922:HEP81_RS26800
uniprot id: A0A7H1Q5R6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS21810
gene id: 146922:HEP81_RS21810
uniprot id: A0A7H1Q2Y7
names: Similarity
messages: Belongs to the peptidase S11 family.

146922:HEP81 RS19430
gene id: 146922:HEP81_RS19430
uniprot id: A0A7H1Q1N2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS21505
gene id: 146922:HEP81_RS21505
uniprot id: A0A426S2F8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

146922:HEP81 RS28095
gene id: 146922:HEP81_RS28095
uniprot id: A0A7H1Q6H0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

146922:HEP81 RS02080
gene id: 146922:HEP81_RS02080
uniprot id: A0A7H1PRS0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS17510
gene id: 146922:HEP81_RS17510
uniprot id: A0A7H1Q0J6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

146922:HEP81 RS29070
gene id: 146922:HEP81_RS29070
uniprot id: A0A1X4GM48
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS35170
gene id: 146922:HEP81_RS35170
uniprot id: A0A426SC65
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

146922:HEP81 RS15250
gene id: 146922:HEP81_RS15250
uniprot id: A0A7H1PZA4
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

146922:HEP81 RS20215
gene id: 146922:HEP81_RS20215
uniprot id: A0A7H1Q223
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

146922:HEP81 RS04975
gene id: 146922:HEP81_RS04975
uniprot id: A0A7H1PTF3
names: Similarity
messages: Belongs to the thioesterase family.

146922:HEP81 RS23990
gene id: 146922:HEP81_RS23990
uniprot id: A0A1X4GPQ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS34375
gene id: 146922:HEP81_RS34375
uniprot id: A0A7H1QA20
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS05305
gene id: 146922:HEP81_RS05305
uniprot id: A0A7H1PTM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

146922:HEP81 RS24150
gene id: 146922:HEP81_RS24150
uniprot id: A0A1X4GQ13
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS27605
gene id: 146922:HEP81_RS27605
uniprot id: A0A3R8QM03
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

146922:HEP81 RS15390
gene id: 146922:HEP81_RS15390
uniprot id: A0A7H1PZD1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS19425
gene id: 146922:HEP81_RS19425
uniprot id: A0A1X4GRJ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

146922:HEP81 RS25440
gene id: 146922:HEP81_RS25440
uniprot id: A0A7H1Q501
names: Similarity
messages: Belongs to the disproportionating enzyme family.

146922:HEP81 RS28550
gene id: 146922:HEP81_RS28550
uniprot id: A0A7H1Q6R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

146922:HEP81 RS10360
gene id: 146922:HEP81_RS10360
uniprot id: A0A3R8QDI6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

146922:HEP81 RS22105
gene id: 146922:HEP81_RS22105
uniprot id: A0A7H1Q348
names: Similarity
messages: Belongs to the peptidase S58 family.

146922:HEP81 RS05825
gene id: 146922:HEP81_RS05825
uniprot id: A0A7H1PTX5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

146922:HEP81 RS20945
gene id: 146922:HEP81_RS20945
uniprot id: A0A7H1Q2G4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

146922:HEP81 RS04235
gene id: 146922:HEP81_RS04235
uniprot id: A0A7H1PT05
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

146922:HEP81 RS17500
gene id: 146922:HEP81_RS17500
uniprot id: A0A7H1Q0J4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

146922:HEP81 RS26145
gene id: 146922:HEP81_RS26145
uniprot id: A0A7H1Q5D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS21265
gene id: 146922:HEP81_RS21265
uniprot id: A0A7H1Q2M8
names: Subcellular Location Annotation
messages: Cell membrane

146922:HEP81 RS28505
gene id: 146922:HEP81_RS28505
uniprot id: A0A3R8RHH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

146922:HEP81 RS28310
gene id: 146922:HEP81_RS28310
uniprot id: A0A1X4GMD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

146922:HEP81 RS16705
gene id: 146922:HEP81_RS16705
uniprot id: A0A3R8WMD3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS28710
gene id: 146922:HEP81_RS28710
uniprot id: A0A7H1Q6U3
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

146922:HEP81 RS04310
gene id: 146922:HEP81_RS04310
uniprot id: A0A7H1PT20
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

146922:HEP81 RS25570
gene id: 146922:HEP81_RS25570
uniprot id: A0A7H1Q527
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

146922:HEP81 RS31315
gene id: 146922:HEP81_RS31315
uniprot id: A0A3R8REM1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

146922:HEP81 RS24925
gene id: 146922:HEP81_RS24925
uniprot id: A0A3R8QGH8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS29520
gene id: 146922:HEP81_RS29520
uniprot id: A0A1X4GM83
names: Similarity
messages: Belongs to the asp23 family.

146922:HEP81 RS14350
gene id: 146922:HEP81_RS14350
uniprot id: A0A1X4GU42
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

146922:HEP81 RS29745
gene id: 146922:HEP81_RS29745
uniprot id: A0A426SDX5
names: Similarity
messages: Belongs to the UPF0098 family.

146922:HEP81 RS13740
gene id: 146922:HEP81_RS13740
uniprot id: A0A7H1PYF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

146922:HEP81 RS35245
gene id: 146922:HEP81_RS35245
uniprot id: A0A7H1QAJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS37055
gene id: 146922:HEP81_RS37055
uniprot id: A0A7H1QBK6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

146922:HEP81 RS05995
gene id: 146922:HEP81_RS05995
uniprot id: A0A1X4GYA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

146922:HEP81 RS04885
gene id: 146922:HEP81_RS04885
uniprot id: A0A7H1PTD5
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

146922:HEP81 RS23720
gene id: 146922:HEP81_RS23720
uniprot id: A0A426RX61
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monovalent cation. The ion could be potassium.

146922:HEP81 RS37695
gene id: 146922:HEP81_RS37695
uniprot id: A0A7H1QBY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

146922:HEP81 RS06975
gene id: 146922:HEP81_RS06975
uniprot id: A0A7H1PUK2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

146922:HEP81 RS03250
gene id: 146922:HEP81_RS03250
uniprot id: A0A7H1PSF8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

146922:HEP81 RS13020
gene id: 146922:HEP81_RS13020
uniprot id: A0A7H1PY14
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

146922:HEP81 RS24955
gene id: 146922:HEP81_RS24955
uniprot id: A0A7H1Q4Q5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

146922:HEP81 RS14725
gene id: 146922:HEP81_RS14725
uniprot id: A0A7H1PZ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

146922:HEP81 RS12165
gene id: 146922:HEP81_RS12165
uniprot id: A0A426S0S1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

146922:HEP81 RS33870
gene id: 146922:HEP81_RS33870
uniprot id: A0A1X4H4Q7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

146922:HEP81 RS22525
gene id: 146922:HEP81_RS22525
uniprot id: A0A7H1Q3D2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS13270
gene id: 146922:HEP81_RS13270
uniprot id: A0A426S330
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

146922:HEP81 RS16860
gene id: 146922:HEP81_RS16860
uniprot id: A0A3R8WME5
names: Similarity
messages: Belongs to the UbiD family.

146922:HEP81 RS27920
gene id: 146922:HEP81_RS27920
uniprot id: A0A7H1Q6D5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

146922:HEP81 RS33775
gene id: 146922:HEP81_RS33775
uniprot id: A0A7H1Q9P7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS34035
gene id: 146922:HEP81_RS34035
uniprot id: A0A7H1Q9U9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

146922:HEP81 RS06415
gene id: 146922:HEP81_RS06415
uniprot id: A0A7H1PU94
names: Caution
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS23750
gene id: 146922:HEP81_RS23750
uniprot id: A0A426RX15
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS25680
gene id: 146922:HEP81_RS25680
uniprot id: A0A1X4GP12
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

146922:HEP81 RS30620
gene id: 146922:HEP81_RS30620
uniprot id: A0A7H1Q7X2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

146922:HEP81 RS20745
gene id: 146922:HEP81_RS20745
uniprot id: A0A7H1Q2C5
names: Similarity
messages: Belongs to the peptidase C40 family.

146922:HEP81 RS19595
gene id: 146922:HEP81_RS19595
uniprot id: A0A7H1Q1R5
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

146922:HEP81 RS02150
gene id: 146922:HEP81_RS02150
uniprot id: A0A7H1PRT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Vgb family.
messages: Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.
messages: Monomer.

146922:HEP81 RS27450
gene id: 146922:HEP81_RS27450
uniprot id: A0A1X4GN10
names: Similarity
messages: Belongs to the glutamine synthetase family.

146922:HEP81 RS02575
gene id: 146922:HEP81_RS02575
uniprot id: A0A7H1PS22
names: Similarity
messages: Belongs to the universal stress protein A family.

146922:HEP81 RS12475
gene id: 146922:HEP81_RS12475
uniprot id: A0A7H1PXQ4
names: Similarity
messages: Belongs to the agmatine deiminase family.

146922:HEP81 RS34330
gene id: 146922:HEP81_RS34330
uniprot id: A0A7H1QA09
names: Similarity
messages: Belongs to the UPF0166 family.

146922:HEP81 RS42225
gene id: 146922:HEP81_RS42225
uniprot id: A0A7H1QA50
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

146922:HEP81 RS32840
gene id: 146922:HEP81_RS32840
uniprot id: A0A7H1Q959
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

146922:HEP81 RS11285
gene id: 146922:HEP81_RS11285
uniprot id: A0A426SB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS18795
gene id: 146922:HEP81_RS18795
uniprot id: A0A3R8SER2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

146922:HEP81 RS14810
gene id: 146922:HEP81_RS14810
uniprot id: A0A7H1PZ20
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS35800
gene id: 146922:HEP81_RS35800
uniprot id: A0A7H1QAV4
names: Similarity
messages: Belongs to the universal stress protein A family.

146922:HEP81 RS07060
gene id: 146922:HEP81_RS07060
uniprot id: A0A7H1PUL8
names: Similarity
messages: Belongs to the universal stress protein A family.

146922:HEP81 RS35410
gene id: 146922:HEP81_RS35410
uniprot id: A0A7H1QAM9
names: Similarity
messages: Belongs to the fructosamine kinase family.

146922:HEP81 RS11630
gene id: 146922:HEP81_RS11630
uniprot id: A0A426S0K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

146922:HEP81 RS23700
gene id: 146922:HEP81_RS23700
uniprot id: A0A7H1Q417
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

146922:HEP81 RS21450
gene id: 146922:HEP81_RS21450
uniprot id: A0A3R8SA23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

146922:HEP81 RS11770
gene id: 146922:HEP81_RS11770
uniprot id: A0A7H1PXB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

146922:HEP81 RS24420
gene id: 146922:HEP81_RS24420
uniprot id: A0A426S5G6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS24880
gene id: 146922:HEP81_RS24880
uniprot id: A0A7H1Q4P0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

146922:HEP81 RS29620
gene id: 146922:HEP81_RS29620
uniprot id: A0A7H1Q7C4
names: Similarity
messages: Belongs to the peptidase U62 family.

146922:HEP81 RS02795
gene id: 146922:HEP81_RS02795
uniprot id: A0A7H1PS66
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

146922:HEP81 RS31755
gene id: 146922:HEP81_RS31755
uniprot id: A0A7H1Q8J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

146922:HEP81 RS11935
gene id: 146922:HEP81_RS11935
uniprot id: A0A3R8QDA2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS18290
gene id: 146922:HEP81_RS18290
uniprot id: A0A7H1Q103
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS02520
gene id: 146922:HEP81_RS02520
uniprot id: A0A7H1PS10
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

146922:HEP81 RS31540
gene id: 146922:HEP81_RS31540
uniprot id: A0A7H1Q8E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

146922:HEP81 RS31140
gene id: 146922:HEP81_RS31140
uniprot id: A0A3R8QH52
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

146922:HEP81 RS27365
gene id: 146922:HEP81_RS27365
uniprot id: A0A7H1Q626
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS29645
gene id: 146922:HEP81_RS29645
uniprot id: A0A1X4GM63
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS28025
gene id: 146922:HEP81_RS28025
uniprot id: A0A7H1Q6F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

146922:HEP81 RS12130
gene id: 146922:HEP81_RS12130
uniprot id: A0A426S0V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

146922:HEP81 RS27590
gene id: 146922:HEP81_RS27590
uniprot id: A0A3R8QFZ4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

146922:HEP81 RS27845
gene id: 146922:HEP81_RS27845
uniprot id: A0A3R8QLX5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

146922:HEP81 RS16275
gene id: 146922:HEP81_RS16275
uniprot id: A0A3R8RY72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

146922:HEP81 RS21430
gene id: 146922:HEP81_RS21430
uniprot id: A0A3R8QEA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

146922:HEP81 RS16670
gene id: 146922:HEP81_RS16670
uniprot id: A0A1X4GTI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS29415
gene id: 146922:HEP81_RS29415
uniprot id: A0A7H1Q783
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

146922:HEP81 RS14375
gene id: 146922:HEP81_RS14375
uniprot id: A0A7H1PYT1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS12205
gene id: 146922:HEP81_RS12205
uniprot id: A0A7H1PXK5
names: Similarity
messages: Belongs to the heat shock protein 90 family.

146922:HEP81 RS23675
gene id: 146922:HEP81_RS23675
uniprot id: A0A7H1Q412
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

146922:HEP81 RS38055
gene id: 146922:HEP81_RS38055
uniprot id: A0A3R8S739
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS11565
gene id: 146922:HEP81_RS11565
uniprot id: A0A1X4GVM8
names: Similarity
messages: Belongs to the WXG100 family.

146922:HEP81 RS07265
gene id: 146922:HEP81_RS07265
uniprot id: A0A7H1PUR0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

146922:HEP81 RS25855
gene id: 146922:HEP81_RS25855
uniprot id: A0A1X4GNV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

146922:HEP81 RS13285
gene id: 146922:HEP81_RS13285
uniprot id: A0A3R8Q8L7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS21590
gene id: 146922:HEP81_RS21590
uniprot id: A0A7H1Q2U3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS11895
gene id: 146922:HEP81_RS11895
uniprot id: A0A426S0K5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

146922:HEP81 RS22060
gene id: 146922:HEP81_RS22060
uniprot id: A0A7H1Q339
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

146922:HEP81 RS04700
gene id: 146922:HEP81_RS04700
uniprot id: A0A7H1PT97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

146922:HEP81 RS32315
gene id: 146922:HEP81_RS32315
uniprot id: A0A7H1Q8U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

146922:HEP81 RS22440
gene id: 146922:HEP81_RS22440
uniprot id: A0A3R8Q5G7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

146922:HEP81 RS31485
gene id: 146922:HEP81_RS31485
uniprot id: A0A7H1Q8D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS30970
gene id: 146922:HEP81_RS30970
uniprot id: A0A7H1Q841
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

146922:HEP81 RS25730
gene id: 146922:HEP81_RS25730
uniprot id: A0A426S635
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS36055
gene id: 146922:HEP81_RS36055
uniprot id: A0A426S957
names: Caution
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS15145
gene id: 146922:HEP81_RS15145
uniprot id: A0A1X4GU36
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

146922:HEP81 RS24475
gene id: 146922:HEP81_RS24475
uniprot id: A0A426S566
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

146922:HEP81 RS30145
gene id: 146922:HEP81_RS30145
uniprot id: A0A7H1Q7M7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS33355
gene id: 146922:HEP81_RS33355
uniprot id: A0A1X4H4T0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS19690
gene id: 146922:HEP81_RS19690
uniprot id: A0A426S9Z9
names: Similarity
messages: Belongs to the peptidase M24B family.

146922:HEP81 RS25925
gene id: 146922:HEP81_RS25925
uniprot id: A0A1X4GNL0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

146922:HEP81 RS28635
gene id: 146922:HEP81_RS28635
uniprot id: A0A7H1Q6S7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

146922:HEP81 RS07035
gene id: 146922:HEP81_RS07035
uniprot id: A0A7H1PUL4
names: Similarity
messages: Belongs to the CdaR family.

146922:HEP81 RS13295
gene id: 146922:HEP81_RS13295
uniprot id: A0A7H1PY69
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS22405
gene id: 146922:HEP81_RS22405
uniprot id: A0A7H1Q3A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

146922:HEP81 RS09430
gene id: 146922:HEP81_RS09430
uniprot id: A0A7H1PW04
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

146922:HEP81 RS30645
gene id: 146922:HEP81_RS30645
uniprot id: A0A7H1Q7X7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS39150
gene id: 146922:HEP81_RS39150
uniprot id: A0A7H1PQM4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

146922:HEP81 RS12585
gene id: 146922:HEP81_RS12585
uniprot id: A0A7H1PXS7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS03080
gene id: 146922:HEP81_RS03080
uniprot id: A0A7H1PSC4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

146922:HEP81 RS13300
gene id: 146922:HEP81_RS13300
uniprot id: A0A7H1PY70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS00120
gene id: 146922:HEP81_RS00120
uniprot id: A0A7H1QCQ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS29820
gene id: 146922:HEP81_RS29820
uniprot id: A0A426S750
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS24470
gene id: 146922:HEP81_RS24470
uniprot id: A0A7H1Q4G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS07090
gene id: 146922:HEP81_RS07090
uniprot id: A0A7H1PUM4
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS31890
gene id: 146922:HEP81_RS31890
uniprot id: A0A426RYL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

146922:HEP81 RS14720
gene id: 146922:HEP81_RS14720
uniprot id: A0A7H1PZ01
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

146922:HEP81 RS16290
gene id: 146922:HEP81_RS16290
uniprot id: A0A426S1U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

146922:HEP81 RS39585
gene id: 146922:HEP81_RS39585
uniprot id: A0A7H1QCZ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

146922:HEP81 RS37160
gene id: 146922:HEP81_RS37160
uniprot id: A0A7H1QBM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

146922:HEP81 RS11795
gene id: 146922:HEP81_RS11795
uniprot id: A0A3R8RXR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

146922:HEP81 RS29130
gene id: 146922:HEP81_RS29130
uniprot id: A0A7H1Q726
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS12290
gene id: 146922:HEP81_RS12290
uniprot id: A0A7H1PXM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

146922:HEP81 RS31240
gene id: 146922:HEP81_RS31240
uniprot id: A0A7H1Q889
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

146922:HEP81 RS15555
gene id: 146922:HEP81_RS15555
uniprot id: A0A7H1PZG4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

146922:HEP81 RS35690
gene id: 146922:HEP81_RS35690
uniprot id: A0A7H1QAT2
names: Similarity
messages: Belongs to the HypE family.

146922:HEP81 RS31165
gene id: 146922:HEP81_RS31165
uniprot id: A0A7H1Q874
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

146922:HEP81 RS02585
gene id: 146922:HEP81_RS02585
uniprot id: A0A7H1PS24
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

146922:HEP81 RS03785
gene id: 146922:HEP81_RS03785
uniprot id: A0A7H1PSR5
names: Similarity
messages: Belongs to the peptidase S33 family.

146922:HEP81 RS12625
gene id: 146922:HEP81_RS12625
uniprot id: A0A7H1PXT5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

146922:HEP81 RS12680
gene id: 146922:HEP81_RS12680
uniprot id: A0A7H1PXU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS25945
gene id: 146922:HEP81_RS25945
uniprot id: A0A426SFP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

146922:HEP81 RS24035
gene id: 146922:HEP81_RS24035
uniprot id: A0A7H1Q480
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

146922:HEP81 RS02640
gene id: 146922:HEP81_RS02640
uniprot id: A0A7H1PS35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS26085
gene id: 146922:HEP81_RS26085
uniprot id: A0A7H1Q5C7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS05685
gene id: 146922:HEP81_RS05685
uniprot id: A0A7H1PTU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm

146922:HEP81 RS31160
gene id: 146922:HEP81_RS31160
uniprot id: A0A3R8QGM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

146922:HEP81 RS22305
gene id: 146922:HEP81_RS22305
uniprot id: A0A3R8RFG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

146922:HEP81 RS34335
gene id: 146922:HEP81_RS34335
uniprot id: A0A3R8QF12
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

146922:HEP81 RS30555
gene id: 146922:HEP81_RS30555
uniprot id: A0A3R8QBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

146922:HEP81 RS02730
gene id: 146922:HEP81_RS02730
uniprot id: A0A7H1PS53
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS17245
gene id: 146922:HEP81_RS17245
uniprot id: A0A1X4GT64
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS19415
gene id: 146922:HEP81_RS19415
uniprot id: A0A3R8QIX0
names: Similarity
messages: Belongs to the FemABX family.

146922:HEP81 RS21790
gene id: 146922:HEP81_RS21790
uniprot id: A0A7H1Q2Y3
names: Similarity
messages: Belongs to the peptidase S33 family.

146922:HEP81 RS35650
gene id: 146922:HEP81_RS35650
uniprot id: A0A426S935
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

146922:HEP81 RS15165
gene id: 146922:HEP81_RS15165
uniprot id: A0A3R8QDV6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS28170
gene id: 146922:HEP81_RS28170
uniprot id: A0A426SEK5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS11065
gene id: 146922:HEP81_RS11065
uniprot id: A0A7H1PWY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

146922:HEP81 RS19315
gene id: 146922:HEP81_RS19315
uniprot id: A0A426SA68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

146922:HEP81 RS13330
gene id: 146922:HEP81_RS13330
uniprot id: A0A7H1PY76
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

146922:HEP81 RS11910
gene id: 146922:HEP81_RS11910
uniprot id: A0A3R8R908
names: Similarity
messages: Belongs to the ABC transporter superfamily.

146922:HEP81 RS13900
gene id: 146922:HEP81_RS13900
uniprot id: A0A7H1PYI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

146922:HEP81 RS03345
gene id: 146922:HEP81_RS03345
uniprot id: A0A7H1PSH7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS19165
gene id: 146922:HEP81_RS19165
uniprot id: A0A426SAB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

146922:HEP81 RS12530
gene id: 146922:HEP81_RS12530
uniprot id: A0A426S0M7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

146922:HEP81 RS09260
gene id: 146922:HEP81_RS09260
uniprot id: A0A7H1PVX0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

146922:HEP81 RS20095
gene id: 146922:HEP81_RS20095
uniprot id: A0A3R8WV86
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

146922:HEP81 RS18615
gene id: 146922:HEP81_RS18615
uniprot id: A0A7H1Q170
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

146922:HEP81 RS12990
gene id: 146922:HEP81_RS12990
uniprot id: A0A7H1PY08
names: Subcellular Location Annotation
messages: Cytoplasm

146922:HEP81 RS27095
gene id: 146922:HEP81_RS27095
uniprot id: A0A3R8QM40
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

146922:HEP81 RS29735
gene id: 146922:HEP81_RS29735
uniprot id: A0A1X4GLR1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

146922:HEP81 RS19225
gene id: 146922:HEP81_RS19225
uniprot id: A0A1X4GRU6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

146922:HEP81 RS04785
gene id: 146922:HEP81_RS04785
uniprot id: A0A7H1PTB5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS29145
gene id: 146922:HEP81_RS29145
uniprot id: A0A7H1Q729
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

146922:HEP81 RS28975
gene id: 146922:HEP81_RS28975
uniprot id: A0A7H1Q6Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

146922:HEP81 RS12740
gene id: 146922:HEP81_RS12740
uniprot id: A0A1X4GVJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS17535
gene id: 146922:HEP81_RS17535
uniprot id: A0A7H1Q0K2
names: Subcellular Location Annotation
messages: Mitochondrion

146922:HEP81 RS30900
gene id: 146922:HEP81_RS30900
uniprot id: A0A7H1Q827
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS31960
gene id: 146922:HEP81_RS31960
uniprot id: A0A7H1Q8M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

146922:HEP81 RS03060
gene id: 146922:HEP81_RS03060
uniprot id: A0A7H1PSC0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS15365
gene id: 146922:HEP81_RS15365
uniprot id: A0A7H1PZC6
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

146922:HEP81 RS07405
gene id: 146922:HEP81_RS07405
uniprot id: A0A7H1PUT9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

146922:HEP81 RS33510
gene id: 146922:HEP81_RS33510
uniprot id: A0A7H1Q9J4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

146922:HEP81 RS30665
gene id: 146922:HEP81_RS30665
uniprot id: A0A7H1Q7Y1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

146922:HEP81 RS26175
gene id: 146922:HEP81_RS26175
uniprot id: A0A7H1Q5E5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

146922:HEP81 RS21445
gene id: 146922:HEP81_RS21445
uniprot id: A0A426S2M0
names: Similarity
messages: Belongs to the UPF0309 family.

146922:HEP81 RS12000
gene id: 146922:HEP81_RS12000
uniprot id: A0A7H1PXG4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

146922:HEP81 RS06825
gene id: 146922:HEP81_RS06825
uniprot id: A0A7H1PUH2
names: Similarity
messages: Belongs to the peptidase S66 family.

146922:HEP81 RS37950
gene id: 146922:HEP81_RS37950
uniprot id: A0A7H1QC33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

146922:HEP81 RS01560
gene id: 146922:HEP81_RS01560
uniprot id: A0A7H1PRG5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

146922:HEP81 RS03615
gene id: 146922:HEP81_RS03615
uniprot id: A0A7H1PSN1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

146922:HEP81 RS03920
gene id: 146922:HEP81_RS03920
uniprot id: A0A7H1PSU1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

146922:HEP81 RS40280
gene id: 146922:HEP81_RS40280
uniprot id: A0A7H1QDE1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

146922:HEP81 RS30005
gene id: 146922:HEP81_RS30005
uniprot id: A0A7H1Q7J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS24685
gene id: 146922:HEP81_RS24685
uniprot id: A0A7H1Q4K5
names: Similarity
messages: Belongs to the peptidase C40 family.

146922:HEP81 RS13425
gene id: 146922:HEP81_RS13425
uniprot id: A0A7H1PY94
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

146922:HEP81 RS34840
gene id: 146922:HEP81_RS34840
uniprot id: A0A1X4H5H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

146922:HEP81 RS24285
gene id: 146922:HEP81_RS24285
uniprot id: A0A426S5A8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS27770
gene id: 146922:HEP81_RS27770
uniprot id: A0A7H1Q6A5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS03040
gene id: 146922:HEP81_RS03040
uniprot id: A0A7H1PSB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EfeM/EfeO family.
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

146922:HEP81 RS20885
gene id: 146922:HEP81_RS20885
uniprot id: A0A7H1Q2F3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

146922:HEP81 RS12795
gene id: 146922:HEP81_RS12795
uniprot id: A0A7H1PXW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

146922:HEP81 RS21685
gene id: 146922:HEP81_RS21685
uniprot id: A0A3R8QEM4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS19440
gene id: 146922:HEP81_RS19440
uniprot id: A0A1X4GRQ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

146922:HEP81 RS27345
gene id: 146922:HEP81_RS27345
uniprot id: A0A426SF42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

146922:HEP81 RS04685
gene id: 146922:HEP81_RS04685
uniprot id: A0A3R8RGQ8
names: Similarity
messages: Belongs to the catalase family.

146922:HEP81 RS12260
gene id: 146922:HEP81_RS12260
uniprot id: A0A3R8QDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

146922:HEP81 RS29445
gene id: 146922:HEP81_RS29445
uniprot id: A0A7H1Q789
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

146922:HEP81 RS21360
gene id: 146922:HEP81_RS21360
uniprot id: A0A426S2D2
names: Similarity
messages: Belongs to the FemABX family.

146922:HEP81 RS08180
gene id: 146922:HEP81_RS08180
uniprot id: A0A7H1PVA4
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS13880
gene id: 146922:HEP81_RS13880
uniprot id: A0A3R8SAN6
names: Caution
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS10310
gene id: 146922:HEP81_RS10310
uniprot id: A0A3R8QE86
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS14480
gene id: 146922:HEP81_RS14480
uniprot id: A0A3R8SAU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS15695
gene id: 146922:HEP81_RS15695
uniprot id: A0A7H1PZJ1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

146922:HEP81 RS29940
gene id: 146922:HEP81_RS29940
uniprot id: A0A1X4GLV4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

146922:HEP81 RS07210
gene id: 146922:HEP81_RS07210
uniprot id: A0A7H1PUP8
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

146922:HEP81 RS20795
gene id: 146922:HEP81_RS20795
uniprot id: A0A3R8Q9B3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS32170
gene id: 146922:HEP81_RS32170
uniprot id: A0A426RYR1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

146922:HEP81 RS12560
gene id: 146922:HEP81_RS12560
uniprot id: A0A3R8Q8I2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS06900
gene id: 146922:HEP81_RS06900
uniprot id: A0A3R8SB07
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS26455
gene id: 146922:HEP81_RS26455
uniprot id: A0A7H1Q5J8
names: Similarity
messages: Belongs to the peptidase S8 family.

146922:HEP81 RS25605
gene id: 146922:HEP81_RS25605
uniprot id: A0A426S601
names: Similarity
messages: Belongs to the LacAB/RpiB family.

146922:HEP81 RS12365
gene id: 146922:HEP81_RS12365
uniprot id: A0A1X4GVQ7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS29870
gene id: 146922:HEP81_RS29870
uniprot id: A0A1X4GLQ2
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

146922:HEP81 RS30530
gene id: 146922:HEP81_RS30530
uniprot id: A0A426S6W1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

146922:HEP81 RS32740
gene id: 146922:HEP81_RS32740
uniprot id: A0A426RZ69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

146922:HEP81 RS34345
gene id: 146922:HEP81_RS34345
uniprot id: A0A426SCY1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS27830
gene id: 146922:HEP81_RS27830
uniprot id: A0A7H1Q6B7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS13395
gene id: 146922:HEP81_RS13395
uniprot id: A0A3R8RAL7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

146922:HEP81 RS11605
gene id: 146922:HEP81_RS11605
uniprot id: A0A3R8QDR5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS16905
gene id: 146922:HEP81_RS16905
uniprot id: A0A1X4GSW7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS13240
gene id: 146922:HEP81_RS13240
uniprot id: A0A426S322
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

146922:HEP81 RS11420
gene id: 146922:HEP81_RS11420
uniprot id: A0A3R8RNC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

146922:HEP81 RS13065
gene id: 146922:HEP81_RS13065
uniprot id: A0A426S2Z5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

146922:HEP81 RS25330
gene id: 146922:HEP81_RS25330
uniprot id: A0A3R8REB0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

146922:HEP81 RS14420
gene id: 146922:HEP81_RS14420
uniprot id: A0A7H1PYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS05340
gene id: 146922:HEP81_RS05340
uniprot id: A0A3R8RJQ5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS16635
gene id: 146922:HEP81_RS16635
uniprot id: A0A7H1Q027
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS10985
gene id: 146922:HEP81_RS10985
uniprot id: A0A7H1PWW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

146922:HEP81 RS18570
gene id: 146922:HEP81_RS18570
uniprot id: A0A1X4GS00
names: Subcellular Location Annotation
messages: Cytoplasm

146922:HEP81 RS00260
gene id: 146922:HEP81_RS00260
uniprot id: A0A7H1QCN1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS02855
gene id: 146922:HEP81_RS02855
uniprot id: A0A7H1PS78
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

146922:HEP81 RS03010
gene id: 146922:HEP81_RS03010
uniprot id: A0A7H1PSB0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS08755
gene id: 146922:HEP81_RS08755
uniprot id: A0A7H1PVL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

146922:HEP81 RS16620
gene id: 146922:HEP81_RS16620
uniprot id: A0A3R8QAH7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS21170
gene id: 146922:HEP81_RS21170
uniprot id: A0A426S2G2
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

146922:HEP81 RS32705
gene id: 146922:HEP81_RS32705
uniprot id: A0A3R8Q7T7
names: Similarity
messages: Belongs to the peptidase C40 family.

146922:HEP81 RS08515
gene id: 146922:HEP81_RS08515
uniprot id: A0A3R8RAG5
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

146922:HEP81 RS24170
gene id: 146922:HEP81_RS24170
uniprot id: A0A1X4GPU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

146922:HEP81 RS04595
gene id: 146922:HEP81_RS04595
uniprot id: A0A7H1PT77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS30710
gene id: 146922:HEP81_RS30710
uniprot id: A0A1X4H328
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

146922:HEP81 RS09750
gene id: 146922:HEP81_RS09750
uniprot id: A0A426SBM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS32680
gene id: 146922:HEP81_RS32680
uniprot id: A0A7H1Q927
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

146922:HEP81 RS02510
gene id: 146922:HEP81_RS02510
uniprot id: A0A7H1PS08
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS07315
gene id: 146922:HEP81_RS07315
uniprot id: A0A7H1PUS1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

146922:HEP81 RS08555
gene id: 146922:HEP81_RS08555
uniprot id: A0A7H1PVH9
names: Subunit
messages: Homodimer.

146922:HEP81 RS37700
gene id: 146922:HEP81_RS37700
uniprot id: A0A7H1QBY1
names: Subcellular Location Annotation
messages: cytosol

146922:HEP81 RS37795
gene id: 146922:HEP81_RS37795
uniprot id: A0A7H1QC01
names: Similarity
messages: Belongs to the CFA/CMAS family.

146922:HEP81 RS36720
gene id: 146922:HEP81_RS36720
uniprot id: A0A7H1QBE0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS15565
gene id: 146922:HEP81_RS15565
uniprot id: A0A7H1PZG6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS04305
gene id: 146922:HEP81_RS04305
uniprot id: A0A7H1PT19
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

146922:HEP81 RS14795
gene id: 146922:HEP81_RS14795
uniprot id: A0A7H1PZ17
names: Similarity
messages: Belongs to the GSP E family.

146922:HEP81 RS15520
gene id: 146922:HEP81_RS15520
uniprot id: A0A7H1PZF7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS09900
gene id: 146922:HEP81_RS09900
uniprot id: A0A7H1PW98
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

146922:HEP81 RS36340
gene id: 146922:HEP81_RS36340
uniprot id: A0A7H1QB63
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

146922:HEP81 RS39245
gene id: 146922:HEP81_RS39245
uniprot id: A0A7H1QCS9
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

146922:HEP81 RS25480
gene id: 146922:HEP81_RS25480
uniprot id: A0A7H1Q509
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS28540
gene id: 146922:HEP81_RS28540
uniprot id: A0A7H1Q6Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

146922:HEP81 RS20040
gene id: 146922:HEP81_RS20040
uniprot id: A0A7H1Q1Z6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS14670
gene id: 146922:HEP81_RS14670
uniprot id: A0A3R8RB07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

146922:HEP81 RS17620
gene id: 146922:HEP81_RS17620
uniprot id: A0A7H1Q0L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

146922:HEP81 RS06160
gene id: 146922:HEP81_RS06160
uniprot id: A0A426S4E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

146922:HEP81 RS26050
gene id: 146922:HEP81_RS26050
uniprot id: A0A3R8QGC8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS32720
gene id: 146922:HEP81_RS32720
uniprot id: A0A3R8RB46
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

146922:HEP81 RS19435
gene id: 146922:HEP81_RS19435
uniprot id: A0A1X4GRJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

146922:HEP81 RS24060
gene id: 146922:HEP81_RS24060
uniprot id: A0A426S4X6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

146922:HEP81 RS29200
gene id: 146922:HEP81_RS29200
uniprot id: A0A1X4GM79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

146922:HEP81 RS13120
gene id: 146922:HEP81_RS13120
uniprot id: A0A7H1PY34
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

146922:HEP81 RS33600
gene id: 146922:HEP81_RS33600
uniprot id: A0A7H1Q9L2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS18000
gene id: 146922:HEP81_RS18000
uniprot id: A0A7H1Q0U5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

146922:HEP81 RS27255
gene id: 146922:HEP81_RS27255
uniprot id: A0A7H1Q604
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

146922:HEP81 RS01455
gene id: 146922:HEP81_RS01455
uniprot id: A0A7H1PRE3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

146922:HEP81 RS15875
gene id: 146922:HEP81_RS15875
uniprot id: A0A3R8Q8X3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

146922:HEP81 RS12240
gene id: 146922:HEP81_RS12240
uniprot id: A0A7H1PXL2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

146922:HEP81 RS18855
gene id: 146922:HEP81_RS18855
uniprot id: A0A7H1Q1B8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

146922:HEP81 RS30180
gene id: 146922:HEP81_RS30180
uniprot id: A0A7H1Q7N4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

146922:HEP81 RS13620
gene id: 146922:HEP81_RS13620
uniprot id: A0A1X4GUS3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS17220
gene id: 146922:HEP81_RS17220
uniprot id: A0A426RVW1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

146922:HEP81 RS33645
gene id: 146922:HEP81_RS33645
uniprot id: A0A7H1Q9M1
names: Similarity
messages: Belongs to the UPF0047 family.

146922:HEP81 RS29265
gene id: 146922:HEP81_RS29265
uniprot id: A0A7H1Q753
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

146922:HEP81 RS23615
gene id: 146922:HEP81_RS23615
uniprot id: A0A426RX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

146922:HEP81 RS12020
gene id: 146922:HEP81_RS12020
uniprot id: A0A7H1PXG8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

146922:HEP81 RS20480
gene id: 146922:HEP81_RS20480
uniprot id: A0A7H1Q272
names: Similarity
messages: Belongs to the Nudix hydrolase family.

146922:HEP81 RS17650
gene id: 146922:HEP81_RS17650
uniprot id: A0A7H1Q0M5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

146922:HEP81 RS06505
gene id: 146922:HEP81_RS06505
uniprot id: A0A7H1PUB2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS26590
gene id: 146922:HEP81_RS26590
uniprot id: A0A7H1Q5M6
names: Similarity
messages: Belongs to the aldose epimerase family.

146922:HEP81 RS24595
gene id: 146922:HEP81_RS24595
uniprot id: A0A7H1Q4I8
names: Similarity
messages: Belongs to the UPF0303 family.

146922:HEP81 RS32800
gene id: 146922:HEP81_RS32800
uniprot id: A0A7H1Q951
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

146922:HEP81 RS17585
gene id: 146922:HEP81_RS17585
uniprot id: A0A3R8RV52
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

146922:HEP81 RS29275
gene id: 146922:HEP81_RS29275
uniprot id: A0A7H1Q755
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS32355
gene id: 146922:HEP81_RS32355
uniprot id: A0A3R8QD05
names: Caution
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS22150
gene id: 146922:HEP81_RS22150
uniprot id: A0A7H1Q357
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

146922:HEP81 RS19240
gene id: 146922:HEP81_RS19240
uniprot id: A0A7H1Q1J6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS16735
gene id: 146922:HEP81_RS16735
uniprot id: A0A7H1Q047
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

146922:HEP81 RS31820
gene id: 146922:HEP81_RS31820
uniprot id: A0A7H1Q8K4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

146922:HEP81 RS20780
gene id: 146922:HEP81_RS20780
uniprot id: A0A7H1Q2D2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS28925
gene id: 146922:HEP81_RS28925
uniprot id: A0A7H1Q6Y5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

146922:HEP81 RS26270
gene id: 146922:HEP81_RS26270
uniprot id: A0A426SFL0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

146922:HEP81 RS27665
gene id: 146922:HEP81_RS27665
uniprot id: A0A3R8QFY4
names: Caution
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS19770
gene id: 146922:HEP81_RS19770
uniprot id: A0A7H1Q1U8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS20645
gene id: 146922:HEP81_RS20645
uniprot id: A0A7H1Q2A6
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

146922:HEP81 RS09725
gene id: 146922:HEP81_RS09725
uniprot id: A0A3R8WWB3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS31355
gene id: 146922:HEP81_RS31355
uniprot id: A0A7H1Q8B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

146922:HEP81 RS13005
gene id: 146922:HEP81_RS13005
uniprot id: A0A7H1PY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS09715
gene id: 146922:HEP81_RS09715
uniprot id: A0A7H1PW60
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS11720
gene id: 146922:HEP81_RS11720
uniprot id: A0A7H1PXA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

146922:HEP81 RS24645
gene id: 146922:HEP81_RS24645
uniprot id: A0A7H1Q4J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS21565
gene id: 146922:HEP81_RS21565
uniprot id: A0A7H1Q2T8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS01620
gene id: 146922:HEP81_RS01620
uniprot id: A0A7H1PRH7
names: Similarity
messages: Belongs to the peptidase M1 family.

146922:HEP81 RS25780
gene id: 146922:HEP81_RS25780
uniprot id: A0A1X4GNM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

146922:HEP81 RS13015
gene id: 146922:HEP81_RS13015
uniprot id: A0A7H1PY13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS21965
gene id: 146922:HEP81_RS21965
uniprot id: A0A7H1Q320
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

146922:HEP81 RS15940
gene id: 146922:HEP81_RS15940
uniprot id: A0A3R8Q932
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS25600
gene id: 146922:HEP81_RS25600
uniprot id: A0A7H1Q533
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

146922:HEP81 RS24840
gene id: 146922:HEP81_RS24840
uniprot id: A0A7H1Q4N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS13130
gene id: 146922:HEP81_RS13130
uniprot id: A0A1X4GV67
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

146922:HEP81 RS08545
gene id: 146922:HEP81_RS08545
uniprot id: A0A7H1PVH7
names: Subunit
messages: Homotetramer.

146922:HEP81 RS00495
gene id: 146922:HEP81_RS00495
uniprot id: A0A7H1PQV4
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

146922:HEP81 RS13060
gene id: 146922:HEP81_RS13060
uniprot id: A0A7H1PY22
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

146922:HEP81 RS02215
gene id: 146922:HEP81_RS02215
uniprot id: A0A7H1PRU9
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

146922:HEP81 RS18235
gene id: 146922:HEP81_RS18235
uniprot id: A0A7H1Q0Z1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS31175
gene id: 146922:HEP81_RS31175
uniprot id: A0A7H1Q876
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

146922:HEP81 RS29915
gene id: 146922:HEP81_RS29915
uniprot id: A0A7H1Q7I1
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

146922:HEP81 RS04380
gene id: 146922:HEP81_RS04380
uniprot id: A0A7H1PT34
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS07540
gene id: 146922:HEP81_RS07540
uniprot id: A0A7H1PUX0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

146922:HEP81 RS26380
gene id: 146922:HEP81_RS26380
uniprot id: A0A7H1Q5I6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS08895
gene id: 146922:HEP81_RS08895
uniprot id: A0A7H1PVP7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS25100
gene id: 146922:HEP81_RS25100
uniprot id: A0A7H1Q4T5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

146922:HEP81 RS31230
gene id: 146922:HEP81_RS31230
uniprot id: A0A7H1Q887
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

146922:HEP81 RS12050
gene id: 146922:HEP81_RS12050
uniprot id: A0A7H1PXH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

146922:HEP81 RS08695
gene id: 146922:HEP81_RS08695
uniprot id: A0A7H1PVK7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS30465
gene id: 146922:HEP81_RS30465
uniprot id: A0A3R8WTE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

146922:HEP81 RS21115
gene id: 146922:HEP81_RS21115
uniprot id: A0A7H1Q2J8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

146922:HEP81 RS32815
gene id: 146922:HEP81_RS32815
uniprot id: A0A3R8QCF0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS29955
gene id: 146922:HEP81_RS29955
uniprot id: A0A7H1Q7I9
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

146922:HEP81 RS34930
gene id: 146922:HEP81_RS34930
uniprot id: A0A3R8QKB1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

146922:HEP81 RS22640
gene id: 146922:HEP81_RS22640
uniprot id: A0A1X4GQ46
names: Similarity
messages: Belongs to the ABC transporter superfamily.

146922:HEP81 RS13215
gene id: 146922:HEP81_RS13215
uniprot id: A0A3R8WRC4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

146922:HEP81 RS22825
gene id: 146922:HEP81_RS22825
uniprot id: A0A7H1Q3J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS08380
gene id: 146922:HEP81_RS08380
uniprot id: A0A7H1PVE4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

146922:HEP81 RS29985
gene id: 146922:HEP81_RS29985
uniprot id: A0A3R8RCT0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS25285
gene id: 146922:HEP81_RS25285
uniprot id: A0A426S5M7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

146922:HEP81 RS29475
gene id: 146922:HEP81_RS29475
uniprot id: A0A7H1Q795
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

146922:HEP81 RS03600
gene id: 146922:HEP81_RS03600
uniprot id: A0A426RYH2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

146922:HEP81 RS26205
gene id: 146922:HEP81_RS26205
uniprot id: A0A1X4GNR6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS34940
gene id: 146922:HEP81_RS34940
uniprot id: A0A7H1QAD3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS06985
gene id: 146922:HEP81_RS06985
uniprot id: A0A1X4GXP3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

146922:HEP81 RS29175
gene id: 146922:HEP81_RS29175
uniprot id: A0A7H1Q735
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

146922:HEP81 RS30920
gene id: 146922:HEP81_RS30920
uniprot id: A0A7H1Q831
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS26340
gene id: 146922:HEP81_RS26340
uniprot id: A0A7H1Q5H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

146922:HEP81 RS26505
gene id: 146922:HEP81_RS26505
uniprot id: A0A7H1Q5K8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

146922:HEP81 RS24435
gene id: 146922:HEP81_RS24435
uniprot id: A0A3R8Q9Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

146922:HEP81 RS05930
gene id: 146922:HEP81_RS05930
uniprot id: A0A7H1PTZ6
names: Similarity
messages: Belongs to the peptidase M1 family.

146922:HEP81 RS04645
gene id: 146922:HEP81_RS04645
uniprot id: A0A7H1PT87
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

146922:HEP81 RS16470
gene id: 146922:HEP81_RS16470
uniprot id: A0A1X4GTL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS11685
gene id: 146922:HEP81_RS11685
uniprot id: A0A7H1PXA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

146922:HEP81 RS12080
gene id: 146922:HEP81_RS12080
uniprot id: A0A3R8R917
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS31330
gene id: 146922:HEP81_RS31330
uniprot id: A0A7H1Q8A7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

146922:HEP81 RS25830
gene id: 146922:HEP81_RS25830
uniprot id: A0A426SFB1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS14660
gene id: 146922:HEP81_RS14660
uniprot id: A0A426S3W0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

146922:HEP81 RS12970
gene id: 146922:HEP81_RS12970
uniprot id: A0A7H1PY04
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS26375
gene id: 146922:HEP81_RS26375
uniprot id: A0A7H1Q5I5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS15865
gene id: 146922:HEP81_RS15865
uniprot id: A0A7H1PZM5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS08540
gene id: 146922:HEP81_RS08540
uniprot id: A0A7H1PVH6
names: Similarity
messages: Belongs to the allantoicase family.

146922:HEP81 RS20075
gene id: 146922:HEP81_RS20075
uniprot id: A0A7H1Q201
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

146922:HEP81 RS16165
gene id: 146922:HEP81_RS16165
uniprot id: A0A1X4GTC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

146922:HEP81 RS20185
gene id: 146922:HEP81_RS20185
uniprot id: A0A3R8RGE8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS16060
gene id: 146922:HEP81_RS16060
uniprot id: A0A426S1Q2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

146922:HEP81 RS23725
gene id: 146922:HEP81_RS23725
uniprot id: A0A1X4GQA0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS36565
gene id: 146922:HEP81_RS36565
uniprot id: A0A7H1QBA7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS22395
gene id: 146922:HEP81_RS22395
uniprot id: A0A7H1Q3A6
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS33485
gene id: 146922:HEP81_RS33485
uniprot id: A0A1X4H4J3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

146922:HEP81 RS24720
gene id: 146922:HEP81_RS24720
uniprot id: A0A7H1Q4L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS33230
gene id: 146922:HEP81_RS33230
uniprot id: A0A3R8S569
names: Similarity
messages: Belongs to the ectoine synthase family.

146922:HEP81 RS37810
gene id: 146922:HEP81_RS37810
uniprot id: A0A7H1QC04
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS06600
gene id: 146922:HEP81_RS06600
uniprot id: A0A7H1PUC7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS21040
gene id: 146922:HEP81_RS21040
uniprot id: A0A7H1Q2I3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

146922:HEP81 RS33085
gene id: 146922:HEP81_RS33085
uniprot id: A0A7H1Q9A8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS05410
gene id: 146922:HEP81_RS05410
uniprot id: A0A7H1PTP3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

146922:HEP81 RS31245
gene id: 146922:HEP81_RS31245
uniprot id: A0A1X4H3Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

146922:HEP81 RS12055
gene id: 146922:HEP81_RS12055
uniprot id: A0A1X4GVC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

146922:HEP81 RS13940
gene id: 146922:HEP81_RS13940
uniprot id: A0A7H1PYJ7
names: Similarity
messages: Belongs to the catalase family.

146922:HEP81 RS23505
gene id: 146922:HEP81_RS23505
uniprot id: A0A7H1Q3X8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS31415
gene id: 146922:HEP81_RS31415
uniprot id: A0A426S6K3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

146922:HEP81 RS19160
gene id: 146922:HEP81_RS19160
uniprot id: A0A426SA90
names: Caution
names: Similarity
messages: Belongs to the UPF0749 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS16595
gene id: 146922:HEP81_RS16595
uniprot id: A0A426RVT2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS38880
gene id: 146922:HEP81_RS38880
uniprot id: A0A7H1QCL0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS32730
gene id: 146922:HEP81_RS32730
uniprot id: A0A7H1Q937
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

146922:HEP81 RS32210
gene id: 146922:HEP81_RS32210
uniprot id: A0A7H1Q8S8
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

146922:HEP81 RS18445
gene id: 146922:HEP81_RS18445
uniprot id: A0A7H1Q134
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS37370
gene id: 146922:HEP81_RS37370
uniprot id: A0A7H1QBR7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS11395
gene id: 146922:HEP81_RS11395
uniprot id: A0A7H1PX48
names: Similarity
messages: Belongs to the FPG family.

146922:HEP81 RS10135
gene id: 146922:HEP81_RS10135
uniprot id: A0A7H1PWE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

146922:HEP81 RS34095
gene id: 146922:HEP81_RS34095
uniprot id: A0A7H1Q9W1
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

146922:HEP81 RS12590
gene id: 146922:HEP81_RS12590
uniprot id: A0A7H1PXS8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

146922:HEP81 RS18205
gene id: 146922:HEP81_RS18205
uniprot id: A0A7H1Q0Y5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS25020
gene id: 146922:HEP81_RS25020
uniprot id: A0A7H1Q4R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

146922:HEP81 RS04475
gene id: 146922:HEP81_RS04475
uniprot id: A0A7H1PT53
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

146922:HEP81 RS19045
gene id: 146922:HEP81_RS19045
uniprot id: A0A7H1Q1F8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS40465
gene id: 146922:HEP81_RS40465
uniprot id: A0A7H1QDI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS27930
gene id: 146922:HEP81_RS27930
uniprot id: A0A426SER8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

146922:HEP81 RS10795
gene id: 146922:HEP81_RS10795
uniprot id: A0A7H1PWS8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS19510
gene id: 146922:HEP81_RS19510
uniprot id: A0A7H1Q1P8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

146922:HEP81 RS28445
gene id: 146922:HEP81_RS28445
uniprot id: A0A7H1Q6N9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

146922:HEP81 RS31700
gene id: 146922:HEP81_RS31700
uniprot id: A0A7H1Q8I0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS01585
gene id: 146922:HEP81_RS01585
uniprot id: A0A7H1PRH0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS15935
gene id: 146922:HEP81_RS15935
uniprot id: A0A7H1PZN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

146922:HEP81 RS30485
gene id: 146922:HEP81_RS30485
uniprot id: A0A1X4H2Y4
names: Caution
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS15280
gene id: 146922:HEP81_RS15280
uniprot id: A0A7H1PZB0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS31310
gene id: 146922:HEP81_RS31310
uniprot id: A0A426S6M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

146922:HEP81 RS19275
gene id: 146922:HEP81_RS19275
uniprot id: A0A7H1Q1K2
names: Similarity
messages: Belongs to the UPF0232 family.

146922:HEP81 RS35125
gene id: 146922:HEP81_RS35125
uniprot id: A0A7H1QAH0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

146922:HEP81 RS18695
gene id: 146922:HEP81_RS18695
uniprot id: A0A7H1Q186
names: Similarity
messages: Belongs to the CdaR family.

146922:HEP81 RS28420
gene id: 146922:HEP81_RS28420
uniprot id: A0A7H1Q6N4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

146922:HEP81 RS26210
gene id: 146922:HEP81_RS26210
uniprot id: A0A3R8RJL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS16475
gene id: 146922:HEP81_RS16475
uniprot id: A0A7H1PZZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS17880
gene id: 146922:HEP81_RS17880
uniprot id: A0A426RVN9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS17690
gene id: 146922:HEP81_RS17690
uniprot id: A0A7H1Q0N3
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

146922:HEP81 RS17765
gene id: 146922:HEP81_RS17765
uniprot id: A0A7H1Q0Q0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

146922:HEP81 RS19300
gene id: 146922:HEP81_RS19300
uniprot id: A0A1X4GS34
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

146922:HEP81 RS33570
gene id: 146922:HEP81_RS33570
uniprot id: A0A7H1Q9K6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

146922:HEP81 RS02190
gene id: 146922:HEP81_RS02190
uniprot id: A0A7H1PRU3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS20625
gene id: 146922:HEP81_RS20625
uniprot id: A0A1X4GR73
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS33755
gene id: 146922:HEP81_RS33755
uniprot id: A0A7H1Q9P3
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

146922:HEP81 RS04510
gene id: 146922:HEP81_RS04510
uniprot id: A0A7H1PT60
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

146922:HEP81 RS21680
gene id: 146922:HEP81_RS21680
uniprot id: A0A426S2H7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS35675
gene id: 146922:HEP81_RS35675
uniprot id: A0A7H1QAS9
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

146922:HEP81 RS34730
gene id: 146922:HEP81_RS34730
uniprot id: A0A7H1QA91
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS24905
gene id: 146922:HEP81_RS24905
uniprot id: A0A7H1Q4P5
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

146922:HEP81 RS04365
gene id: 146922:HEP81_RS04365
uniprot id: A0A7H1PT31
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

146922:HEP81 RS17475
gene id: 146922:HEP81_RS17475
uniprot id: A0A1X4GSW4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS30685
gene id: 146922:HEP81_RS30685
uniprot id: A0A7H1Q7Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS08170
gene id: 146922:HEP81_RS08170
uniprot id: A0A7H1PVA2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS25155
gene id: 146922:HEP81_RS25155
uniprot id: A0A7H1Q4U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS16040
gene id: 146922:HEP81_RS16040
uniprot id: A0A1X4GTC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

146922:HEP81 RS03680
gene id: 146922:HEP81_RS03680
uniprot id: A0A3R8Q7E9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

146922:HEP81 RS39530
gene id: 146922:HEP81_RS39530
uniprot id: A0A7H1QCX9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

146922:HEP81 RS15820
gene id: 146922:HEP81_RS15820
uniprot id: A0A7H1PZL6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

146922:HEP81 RS42165
gene id: 146922:HEP81_RS42165
uniprot id: A0A1X4GQW5
names: Subcellular Location Annotation
messages: Cytoplasm

146922:HEP81 RS27595
gene id: 146922:HEP81_RS27595
uniprot id: A0A7H1Q670
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS04425
gene id: 146922:HEP81_RS04425
uniprot id: A0A1X4GZ29
names: Similarity
messages: Belongs to the universal stress protein A family.

146922:HEP81 RS30415
gene id: 146922:HEP81_RS30415
uniprot id: A0A7H1Q7T0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

146922:HEP81 RS17640
gene id: 146922:HEP81_RS17640
uniprot id: A0A426RW47
names: Similarity
messages: Belongs to the group II decarboxylase family.

146922:HEP81 RS04300
gene id: 146922:HEP81_RS04300
uniprot id: A0A7H1PT18
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

146922:HEP81 RS06090
gene id: 146922:HEP81_RS06090
uniprot id: A0A7H1PU28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

146922:HEP81 RS29045
gene id: 146922:HEP81_RS29045
uniprot id: A0A7H1Q709
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

146922:HEP81 RS40730
gene id: 146922:HEP81_RS40730
uniprot id: A0A7H1QDP0
names: Similarity
messages: Belongs to the ParB family.

146922:HEP81 RS14145
gene id: 146922:HEP81_RS14145
uniprot id: A0A7H1PYN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS22130
gene id: 146922:HEP81_RS22130
uniprot id: A0A3R8QEE6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

146922:HEP81 RS11160
gene id: 146922:HEP81_RS11160
uniprot id: A0A1X4GVT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

146922:HEP81 RS13500
gene id: 146922:HEP81_RS13500
uniprot id: A0A7H1PYA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

146922:HEP81 RS16145
gene id: 146922:HEP81_RS16145
uniprot id: A0A1X4GT68
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

146922:HEP81 RS12890
gene id: 146922:HEP81_RS12890
uniprot id: A0A7H1PXY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS33515
gene id: 146922:HEP81_RS33515
uniprot id: A0A7H1Q9J5
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

146922:HEP81 RS11380
gene id: 146922:HEP81_RS11380
uniprot id: A0A7H1PX45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

146922:HEP81 RS16300
gene id: 146922:HEP81_RS16300
uniprot id: A0A7H1PZW3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

146922:HEP81 RS14980
gene id: 146922:HEP81_RS14980
uniprot id: A0A3R8RHG8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

146922:HEP81 RS16105
gene id: 146922:HEP81_RS16105
uniprot id: A0A1X4GTB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

146922:HEP81 RS32145
gene id: 146922:HEP81_RS32145
uniprot id: A0A7H1Q8R6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

146922:HEP81 RS08445
gene id: 146922:HEP81_RS08445
uniprot id: A0A7H1PVF7
names: Similarity
messages: Belongs to the glutamate synthase family.

146922:HEP81 RS06565
gene id: 146922:HEP81_RS06565
uniprot id: A0A7H1PUC0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

146922:HEP81 RS07430
gene id: 146922:HEP81_RS07430
uniprot id: A0A7H1PUU4
names: Similarity
messages: Belongs to the AdoMet synthetase 2 family.

146922:HEP81 RS15880
gene id: 146922:HEP81_RS15880
uniprot id: A0A1X4GTF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

146922:HEP81 RS16055
gene id: 146922:HEP81_RS16055
uniprot id: A0A426S203
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

146922:HEP81 RS31900
gene id: 146922:HEP81_RS31900
uniprot id: A0A7H1Q8L7
names: Similarity
messages: Belongs to the UPF0749 family.

146922:HEP81 RS12220
gene id: 146922:HEP81_RS12220
uniprot id: A0A1X4GVT3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

146922:HEP81 RS37590
gene id: 146922:HEP81_RS37590
uniprot id: A0A7H1QBW0
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS31270
gene id: 146922:HEP81_RS31270
uniprot id: A0A3R8S116
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

146922:HEP81 RS29190
gene id: 146922:HEP81_RS29190
uniprot id: A0A3R8S5S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS13125
gene id: 146922:HEP81_RS13125
uniprot id: A0A1X4GUW6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

146922:HEP81 RS30335
gene id: 146922:HEP81_RS30335
uniprot id: A0A7H1Q7R5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

146922:HEP81 RS19285
gene id: 146922:HEP81_RS19285
uniprot id: A0A426SA16
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

146922:HEP81 RS13795
gene id: 146922:HEP81_RS13795
uniprot id: A0A426S3W8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS05785
gene id: 146922:HEP81_RS05785
uniprot id: A0A7H1PTW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

146922:HEP81 RS02595
gene id: 146922:HEP81_RS02595
uniprot id: A0A7H1PS26
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS35725
gene id: 146922:HEP81_RS35725
uniprot id: A0A7H1QAT9
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

146922:HEP81 RS25350
gene id: 146922:HEP81_RS25350
uniprot id: A0A7H1Q4Y3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

146922:HEP81 RS09695
gene id: 146922:HEP81_RS09695
uniprot id: A0A426SBN6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

146922:HEP81 RS06740
gene id: 146922:HEP81_RS06740
uniprot id: A0A7H1PUF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

146922:HEP81 RS18725
gene id: 146922:HEP81_RS18725
uniprot id: A0A7H1Q192
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

146922:HEP81 RS01480
gene id: 146922:HEP81_RS01480
uniprot id: A0A7H1PRE8
names: Subcellular Location Annotation
messages: Secreted

146922:HEP81 RS21225
gene id: 146922:HEP81_RS21225
uniprot id: A0A3R8QE80
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

146922:HEP81 RS04835
gene id: 146922:HEP81_RS04835
uniprot id: A0A7H1PTC5
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS15410
gene id: 146922:HEP81_RS15410
uniprot id: A0A7H1PZD5
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

146922:HEP81 RS10465
gene id: 146922:HEP81_RS10465
uniprot id: A0A3R8RNJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

146922:HEP81 RS35640
gene id: 146922:HEP81_RS35640
uniprot id: A0A7H1QAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

146922:HEP81 RS20685
gene id: 146922:HEP81_RS20685
uniprot id: A0A7H1Q2B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

146922:HEP81 RS30585
gene id: 146922:HEP81_RS30585
uniprot id: A0A7H1Q7W4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

146922:HEP81 RS11170
gene id: 146922:HEP81_RS11170
uniprot id: A0A426SB84
names: Similarity
messages: Belongs to the RelA/SpoT family.

146922:HEP81 RS24085
gene id: 146922:HEP81_RS24085
uniprot id: A0A426S4Y6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

146922:HEP81 RS26260
gene id: 146922:HEP81_RS26260
uniprot id: A0A7H1Q5G2
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS38485
gene id: 146922:HEP81_RS38485
uniprot id: A0A7H1QCD4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS29580
gene id: 146922:HEP81_RS29580
uniprot id: A0A7H1Q7B6
names: Similarity
messages: Belongs to the peptidase S8 family.

146922:HEP81 RS30990
gene id: 146922:HEP81_RS30990
uniprot id: A0A3R8REP6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

146922:HEP81 RS29925
gene id: 146922:HEP81_RS29925
uniprot id: A0A7H1Q7I3
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

146922:HEP81 RS25715
gene id: 146922:HEP81_RS25715
uniprot id: A0A426S652
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

146922:HEP81 RS04165
gene id: 146922:HEP81_RS04165
uniprot id: A0A7H1PSY9
names: Similarity
messages: Belongs to the UPF0166 family.

146922:HEP81 RS11725
gene id: 146922:HEP81_RS11725
uniprot id: A0A3R8Q6Y9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS35115
gene id: 146922:HEP81_RS35115
uniprot id: A0A3R8RHX3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS20990
gene id: 146922:HEP81_RS20990
uniprot id: A0A7H1Q2H3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS39620
gene id: 146922:HEP81_RS39620
uniprot id: A0A7H1QCZ7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

146922:HEP81 RS27110
gene id: 146922:HEP81_RS27110
uniprot id: A0A3R8SHP0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

146922:HEP81 RS30175
gene id: 146922:HEP81_RS30175
uniprot id: A0A7H1Q7N3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

146922:HEP81 RS33140
gene id: 146922:HEP81_RS33140
uniprot id: A0A3R8WXJ6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS30640
gene id: 146922:HEP81_RS30640
uniprot id: A0A7H1Q7X6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS17810
gene id: 146922:HEP81_RS17810
uniprot id: A0A7H1Q0Q9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

146922:HEP81 RS05710
gene id: 146922:HEP81_RS05710
uniprot id: A0A7H1PTV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS20490
gene id: 146922:HEP81_RS20490
uniprot id: A0A7H1Q274
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

146922:HEP81 RS08480
gene id: 146922:HEP81_RS08480
uniprot id: A0A7H1PVG4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

146922:HEP81 RS33940
gene id: 146922:HEP81_RS33940
uniprot id: A0A7H1Q9T1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

146922:HEP81 RS04015
gene id: 146922:HEP81_RS04015
uniprot id: A0A7H1PSV9
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

146922:HEP81 RS13260
gene id: 146922:HEP81_RS13260
uniprot id: A0A3R8RD01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

146922:HEP81 RS11970
gene id: 146922:HEP81_RS11970
uniprot id: A0A426S0H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

146922:HEP81 RS16250
gene id: 146922:HEP81_RS16250
uniprot id: A0A1X4GT60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

146922:HEP81 RS33150
gene id: 146922:HEP81_RS33150
uniprot id: A0A7H1Q9C1
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS29610
gene id: 146922:HEP81_RS29610
uniprot id: A0A1X4GLZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

146922:HEP81 RS14705
gene id: 146922:HEP81_RS14705
uniprot id: A0A7H1PYZ8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS23735
gene id: 146922:HEP81_RS23735
uniprot id: A0A1X4GQ06
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

146922:HEP81 RS03375
gene id: 146922:HEP81_RS03375
uniprot id: A0A7H1PSI3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS30625
gene id: 146922:HEP81_RS30625
uniprot id: A0A7H1Q7X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

146922:HEP81 RS19390
gene id: 146922:HEP81_RS19390
uniprot id: A0A1X4GS29
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

146922:HEP81 RS14265
gene id: 146922:HEP81_RS14265
uniprot id: A0A426S3M6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS09675
gene id: 146922:HEP81_RS09675
uniprot id: A0A7H1PW52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS35860
gene id: 146922:HEP81_RS35860
uniprot id: A0A7H1QAW6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS17395
gene id: 146922:HEP81_RS17395
uniprot id: A0A1X4GT45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

146922:HEP81 RS19175
gene id: 146922:HEP81_RS19175
uniprot id: A0A7H1Q1I4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

146922:HEP81 RS36865
gene id: 146922:HEP81_RS36865
uniprot id: A0A7H1QBH0
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

146922:HEP81 RS14635
gene id: 146922:HEP81_RS14635
uniprot id: A0A7H1PYY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

146922:HEP81 RS13680
gene id: 146922:HEP81_RS13680
uniprot id: A0A3R8Q9Y2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

146922:HEP81 RS07360
gene id: 146922:HEP81_RS07360
uniprot id: A0A7H1PUT0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS19580
gene id: 146922:HEP81_RS19580
uniprot id: A0A7H1Q1R2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS00885
gene id: 146922:HEP81_RS00885
uniprot id: A0A7H1PR32
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS27080
gene id: 146922:HEP81_RS27080
uniprot id: A0A7H1Q5X1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

146922:HEP81 RS27870
gene id: 146922:HEP81_RS27870
uniprot id: A0A426SES6
names: Caution
names: Similarity
messages: Belongs to the PspA/IM30 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS32805
gene id: 146922:HEP81_RS32805
uniprot id: A0A7H1Q952
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

146922:HEP81 RS22210
gene id: 146922:HEP81_RS22210
uniprot id: A0A3R8RFH2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

146922:HEP81 RS10385
gene id: 146922:HEP81_RS10385
uniprot id: A0A1X4GWJ6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS12040
gene id: 146922:HEP81_RS12040
uniprot id: A0A1X4GVB3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

146922:HEP81 RS02710
gene id: 146922:HEP81_RS02710
uniprot id: A0A7H1PS49
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS16655
gene id: 146922:HEP81_RS16655
uniprot id: A0A7H1Q031
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

146922:HEP81 RS05870
gene id: 146922:HEP81_RS05870
uniprot id: A0A7H1PTY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

146922:HEP81 RS28945
gene id: 146922:HEP81_RS28945
uniprot id: A0A1X4GM35
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

146922:HEP81 RS02615
gene id: 146922:HEP81_RS02615
uniprot id: A0A7H1PS30
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS17890
gene id: 146922:HEP81_RS17890
uniprot id: A0A7H1Q0S3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

146922:HEP81 RS37290
gene id: 146922:HEP81_RS37290
uniprot id: A0A7H1QBQ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS01210
gene id: 146922:HEP81_RS01210
uniprot id: A0A7H1PR98
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the UbiD family. YclC subfamily.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS35695
gene id: 146922:HEP81_RS35695
uniprot id: A0A426S9C2
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

146922:HEP81 RS15840
gene id: 146922:HEP81_RS15840
uniprot id: A0A7H1PZM0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS31045
gene id: 146922:HEP81_RS31045
uniprot id: A0A7H1Q852
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

146922:HEP81 RS31380
gene id: 146922:HEP81_RS31380
uniprot id: A0A7H1Q8B7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS28525
gene id: 146922:HEP81_RS28525
uniprot id: A0A7H1Q6Q5
names: Similarity
messages: Belongs to the TrpC family.

146922:HEP81 RS29615
gene id: 146922:HEP81_RS29615
uniprot id: A0A3R8QLX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

146922:HEP81 RS31235
gene id: 146922:HEP81_RS31235
uniprot id: A0A7H1Q888
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

146922:HEP81 RS13760
gene id: 146922:HEP81_RS13760
uniprot id: A0A7H1PYG1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

146922:HEP81 RS11540
gene id: 146922:HEP81_RS11540
uniprot id: A0A3R8RXD4
names: Similarity
messages: Belongs to the EccD/Snm4 family.

146922:HEP81 RS36320
gene id: 146922:HEP81_RS36320
uniprot id: A0A7H1QB59
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS12030
gene id: 146922:HEP81_RS12030
uniprot id: A0A7H1PXH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

146922:HEP81 RS16330
gene id: 146922:HEP81_RS16330
uniprot id: A0A7H1PZW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

146922:HEP81 RS09365
gene id: 146922:HEP81_RS09365
uniprot id: A0A426SBU6
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

146922:HEP81 RS16575
gene id: 146922:HEP81_RS16575
uniprot id: A0A426RW06
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS33070
gene id: 146922:HEP81_RS33070
uniprot id: A0A1X4H470
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

146922:HEP81 RS17505
gene id: 146922:HEP81_RS17505
uniprot id: A0A7H1Q0J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

146922:HEP81 RS16125
gene id: 146922:HEP81_RS16125
uniprot id: A0A1X4H1J5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

146922:HEP81 RS03605
gene id: 146922:HEP81_RS03605
uniprot id: A0A7H1PSM9
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS03350
gene id: 146922:HEP81_RS03350
uniprot id: A0A7H1PSH8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS16840
gene id: 146922:HEP81_RS16840
uniprot id: A0A3R8REP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

146922:HEP81 RS14495
gene id: 146922:HEP81_RS14495
uniprot id: A0A426S3T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

146922:HEP81 RS18225
gene id: 146922:HEP81_RS18225
uniprot id: A0A1X4GSF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

146922:HEP81 RS17990
gene id: 146922:HEP81_RS17990
uniprot id: A0A7H1Q0U3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS33960
gene id: 146922:HEP81_RS33960
uniprot id: A0A7H1Q9T5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

146922:HEP81 RS29155
gene id: 146922:HEP81_RS29155
uniprot id: A0A1X4GM75
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

146922:HEP81 RS25710
gene id: 146922:HEP81_RS25710
uniprot id: A0A1X4GNR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

146922:HEP81 RS32330
gene id: 146922:HEP81_RS32330
uniprot id: A0A3R8R8A2
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS31865
gene id: 146922:HEP81_RS31865
uniprot id: A0A7H1Q8L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

146922:HEP81 RS29795
gene id: 146922:HEP81_RS29795
uniprot id: A0A3R8RCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

146922:HEP81 RS19625
gene id: 146922:HEP81_RS19625
uniprot id: A0A1X4GRW8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS13690
gene id: 146922:HEP81_RS13690
uniprot id: A0A426S3C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS13830
gene id: 146922:HEP81_RS13830
uniprot id: A0A426S3F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

146922:HEP81 RS33260
gene id: 146922:HEP81_RS33260
uniprot id: A0A7H1Q9E3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS24100
gene id: 146922:HEP81_RS24100
uniprot id: A0A7H1Q493
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

146922:HEP81 RS32865
gene id: 146922:HEP81_RS32865
uniprot id: A0A7H1Q964
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS25395
gene id: 146922:HEP81_RS25395
uniprot id: A0A7H1Q4Z2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

146922:HEP81 RS29845
gene id: 146922:HEP81_RS29845
uniprot id: A0A7H1Q7G6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

146922:HEP81 RS22425
gene id: 146922:HEP81_RS22425
uniprot id: A0A7H1Q3B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

146922:HEP81 RS01795
gene id: 146922:HEP81_RS01795
uniprot id: A0A7H1PRL3
names: Similarity
messages: Belongs to the IucA/IucC family.

146922:HEP81 RS24235
gene id: 146922:HEP81_RS24235
uniprot id: A0A1X4H0Q8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS35910
gene id: 146922:HEP81_RS35910
uniprot id: A0A7H1QAX7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS11960
gene id: 146922:HEP81_RS11960
uniprot id: A0A1X4H1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

146922:HEP81 RS06005
gene id: 146922:HEP81_RS06005
uniprot id: A0A3R8QFJ8
names: Similarity
messages: Belongs to the DDAH family.

146922:HEP81 RS23560
gene id: 146922:HEP81_RS23560
uniprot id: A0A7H1Q3Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

146922:HEP81 RS19070
gene id: 146922:HEP81_RS19070
uniprot id: A0A7H1Q1G3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS11525
gene id: 146922:HEP81_RS11525
uniprot id: A0A1X4GVL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

146922:HEP81 RS27835
gene id: 146922:HEP81_RS27835
uniprot id: A0A7H1Q6B8
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

146922:HEP81 RS16070
gene id: 146922:HEP81_RS16070
uniprot id: A0A1X4GTH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

146922:HEP81 RS14630
gene id: 146922:HEP81_RS14630
uniprot id: A0A7H1PYY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

146922:HEP81 RS29135
gene id: 146922:HEP81_RS29135
uniprot id: A0A7H1Q727
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS29345
gene id: 146922:HEP81_RS29345
uniprot id: A0A3R8WY15
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

146922:HEP81 RS12955
gene id: 146922:HEP81_RS12955
uniprot id: A0A7H1PY01
names: Similarity
messages: Belongs to the thioredoxin family.

146922:HEP81 RS15490
gene id: 146922:HEP81_RS15490
uniprot id: A0A7H1PZF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS19500
gene id: 146922:HEP81_RS19500
uniprot id: A0A7H1Q1P6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS31645
gene id: 146922:HEP81_RS31645
uniprot id: A0A7H1Q8G9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS29090
gene id: 146922:HEP81_RS29090
uniprot id: A0A7H1Q718
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

146922:HEP81 RS33225
gene id: 146922:HEP81_RS33225
uniprot id: A0A7H1Q9D6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS33125
gene id: 146922:HEP81_RS33125
uniprot id: A0A7H1Q9B6
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

146922:HEP81 RS24580
gene id: 146922:HEP81_RS24580
uniprot id: A0A7H1Q4I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

146922:HEP81 RS32390
gene id: 146922:HEP81_RS32390
uniprot id: A0A7H1Q8W5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

146922:HEP81 RS28350
gene id: 146922:HEP81_RS28350
uniprot id: A0A7H1Q6M0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

146922:HEP81 RS25930
gene id: 146922:HEP81_RS25930
uniprot id: A0A426SEZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

146922:HEP81 RS19455
gene id: 146922:HEP81_RS19455
uniprot id: A0A7H1Q1N7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

146922:HEP81 RS31285
gene id: 146922:HEP81_RS31285
uniprot id: A0A7H1Q898
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

146922:HEP81 RS28390
gene id: 146922:HEP81_RS28390
uniprot id: A0A3R8QLQ9
names: Subcellular Location Annotation
messages: Cytoplasm

146922:HEP81 RS29780
gene id: 146922:HEP81_RS29780
uniprot id: A0A3R8RL59
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS04635
gene id: 146922:HEP81_RS04635
uniprot id: A0A7H1PT85
names: Similarity
messages: Belongs to the peptidase S9C family.

146922:HEP81 RS08645
gene id: 146922:HEP81_RS08645
uniprot id: A0A7H1PVJ7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

146922:HEP81 RS15220
gene id: 146922:HEP81_RS15220
uniprot id: A0A1X4GTY6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS10970
gene id: 146922:HEP81_RS10970
uniprot id: A0A7H1PWW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS21090
gene id: 146922:HEP81_RS21090
uniprot id: A0A1X4GQW8
names: Subcellular Location Annotation
messages: Cytoplasm

146922:HEP81 RS12905
gene id: 146922:HEP81_RS12905
uniprot id: A0A7H1PXZ1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS30905
gene id: 146922:HEP81_RS30905
uniprot id: A0A7H1Q828
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

146922:HEP81 RS18310
gene id: 146922:HEP81_RS18310
uniprot id: A0A3R8QDS5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

146922:HEP81 RS17225
gene id: 146922:HEP81_RS17225
uniprot id: A0A7H1Q0E1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

146922:HEP81 RS31895
gene id: 146922:HEP81_RS31895
uniprot id: A0A7H1Q8L6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

146922:HEP81 RS21835
gene id: 146922:HEP81_RS21835
uniprot id: A0A7H1Q2Z2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

146922:HEP81 RS01470
gene id: 146922:HEP81_RS01470
uniprot id: A0A7H1PRE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS32905
gene id: 146922:HEP81_RS32905
uniprot id: A0A7H1Q972
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS12945
gene id: 146922:HEP81_RS12945
uniprot id: A0A7H1PXZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

146922:HEP81 RS31290
gene id: 146922:HEP81_RS31290
uniprot id: A0A7H1Q899
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

146922:HEP81 RS14685
gene id: 146922:HEP81_RS14685
uniprot id: A0A426S3X4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS05045
gene id: 146922:HEP81_RS05045
uniprot id: A0A7H1PTG7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS14640
gene id: 146922:HEP81_RS14640
uniprot id: A0A7H1PYY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

146922:HEP81 RS03440
gene id: 146922:HEP81_RS03440
uniprot id: A0A7H1PSJ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS28175
gene id: 146922:HEP81_RS28175
uniprot id: A0A426SES0
names: Caution
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS26010
gene id: 146922:HEP81_RS26010
uniprot id: A0A7H1Q5B2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

146922:HEP81 RS28870
gene id: 146922:HEP81_RS28870
uniprot id: A0A3R8QN09
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS03405
gene id: 146922:HEP81_RS03405
uniprot id: A0A426RY91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted
messages: Strong inhibitor of bacterial serine proteases such as subtilisin.

146922:HEP81 RS19545
gene id: 146922:HEP81_RS19545
uniprot id: A0A7H1Q1Q5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

146922:HEP81 RS33145
gene id: 146922:HEP81_RS33145
uniprot id: A0A7H1Q9C0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS31455
gene id: 146922:HEP81_RS31455
uniprot id: A0A7H1Q8D2
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

146922:HEP81 RS15360
gene id: 146922:HEP81_RS15360
uniprot id: A0A426S1N1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS37790
gene id: 146922:HEP81_RS37790
uniprot id: A0A7H1QC00
names: Similarity
messages: Belongs to the CFA/CMAS family.

146922:HEP81 RS06715
gene id: 146922:HEP81_RS06715
uniprot id: A0A3R8RB85
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS09345
gene id: 146922:HEP81_RS09345
uniprot id: A0A7H1PVY7
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

146922:HEP81 RS03840
gene id: 146922:HEP81_RS03840
uniprot id: A0A7H1PSS6
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

146922:HEP81 RS20455
gene id: 146922:HEP81_RS20455
uniprot id: A0A1X4GR31
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

146922:HEP81 RS12605
gene id: 146922:HEP81_RS12605
uniprot id: A0A1X4GV20
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

146922:HEP81 RS12170
gene id: 146922:HEP81_RS12170
uniprot id: A0A7H1PXJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

146922:HEP81 RS06920
gene id: 146922:HEP81_RS06920
uniprot id: A0A426S444
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

146922:HEP81 RS05640
gene id: 146922:HEP81_RS05640
uniprot id: A0A7H1PTT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

146922:HEP81 RS05830
gene id: 146922:HEP81_RS05830
uniprot id: A0A1X4GXW5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

146922:HEP81 RS04535
gene id: 146922:HEP81_RS04535
uniprot id: A0A7H1PT65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

146922:HEP81 RS33130
gene id: 146922:HEP81_RS33130
uniprot id: A0A7H1Q9B7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS04470
gene id: 146922:HEP81_RS04470
uniprot id: A0A7H1PT52
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

146922:HEP81 RS17805
gene id: 146922:HEP81_RS17805
uniprot id: A0A426RVI3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

146922:HEP81 RS27420
gene id: 146922:HEP81_RS27420
uniprot id: A0A7H1Q637
names: Similarity
messages: Belongs to the peptidase S33 family.

146922:HEP81 RS37405
gene id: 146922:HEP81_RS37405
uniprot id: A0A7H1QBS3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS24785
gene id: 146922:HEP81_RS24785
uniprot id: A0A7H1Q4M2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS04180
gene id: 146922:HEP81_RS04180
uniprot id: A0A7H1PSZ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS17900
gene id: 146922:HEP81_RS17900
uniprot id: A0A1X4GSP7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

146922:HEP81 RS38375
gene id: 146922:HEP81_RS38375
uniprot id: A0A7H1QCB4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

146922:HEP81 RS08860
gene id: 146922:HEP81_RS08860
uniprot id: A0A426SBR1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS26825
gene id: 146922:HEP81_RS26825
uniprot id: A0A1X4GN35
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

146922:HEP81 RS12880
gene id: 146922:HEP81_RS12880
uniprot id: A0A7H1PXY6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS02685
gene id: 146922:HEP81_RS02685
uniprot id: A0A7H1PS44
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS30980
gene id: 146922:HEP81_RS30980
uniprot id: A0A7H1Q843
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

146922:HEP81 RS31205
gene id: 146922:HEP81_RS31205
uniprot id: A0A3R8RKM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

146922:HEP81 RS14240
gene id: 146922:HEP81_RS14240
uniprot id: A0A3R8WRN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

146922:HEP81 RS35050
gene id: 146922:HEP81_RS35050
uniprot id: A0A7H1QAF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

146922:HEP81 RS16020
gene id: 146922:HEP81_RS16020
uniprot id: A0A7H1PZQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS19480
gene id: 146922:HEP81_RS19480
uniprot id: A0A426S9X3
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS17715
gene id: 146922:HEP81_RS17715
uniprot id: A0A1X4H115
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

146922:HEP81 RS31995
gene id: 146922:HEP81_RS31995
uniprot id: A0A3R8RWI5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS16000
gene id: 146922:HEP81_RS16000
uniprot id: A0A7H1PZQ3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

146922:HEP81 RS15270
gene id: 146922:HEP81_RS15270
uniprot id: A0A7H1PZA8
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

146922:HEP81 RS33470
gene id: 146922:HEP81_RS33470
uniprot id: A0A7H1Q9I7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

146922:HEP81 RS29595
gene id: 146922:HEP81_RS29595
uniprot id: A0A7H1Q7B9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

146922:HEP81 RS24370
gene id: 146922:HEP81_RS24370
uniprot id: A0A1X4GPX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

146922:HEP81 RS06945
gene id: 146922:HEP81_RS06945
uniprot id: A0A426S405
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS25560
gene id: 146922:HEP81_RS25560
uniprot id: A0A3R8REC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

146922:HEP81 RS14325
gene id: 146922:HEP81_RS14325
uniprot id: A0A3R8QA45
names: Similarity
messages: Belongs to the LOG family.

146922:HEP81 RS16135
gene id: 146922:HEP81_RS16135
uniprot id: A0A1X4GTS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

146922:HEP81 RS23730
gene id: 146922:HEP81_RS23730
uniprot id: A0A7H1Q423
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

146922:HEP81 RS41570
gene id: 146922:HEP81_RS41570
uniprot id: A0A7H1Q2Z5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS01215
gene id: 146922:HEP81_RS01215
uniprot id: A0A7H1PR99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UbiX/PAD1 family. YclB subfamily.
messages: Homododecamer.
messages: Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase.

146922:HEP81 RS14275
gene id: 146922:HEP81_RS14275
uniprot id: A0A7H1PYR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

146922:HEP81 RS13985
gene id: 146922:HEP81_RS13985
uniprot id: A0A3R8SAP5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS11760
gene id: 146922:HEP81_RS11760
uniprot id: A0A7H1PXB6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS18315
gene id: 146922:HEP81_RS18315
uniprot id: A0A1X4GSM9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS05465
gene id: 146922:HEP81_RS05465
uniprot id: A0A3R8QAS1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

146922:HEP81 RS16150
gene id: 146922:HEP81_RS16150
uniprot id: A0A1X4GTA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

146922:HEP81 RS02320
gene id: 146922:HEP81_RS02320
uniprot id: A0A7H1PRX1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS07235
gene id: 146922:HEP81_RS07235
uniprot id: A0A3R8S7K0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS27035
gene id: 146922:HEP81_RS27035
uniprot id: A0A7H1Q5W3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS26080
gene id: 146922:HEP81_RS26080
uniprot id: A0A1X4GNN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS03070
gene id: 146922:HEP81_RS03070
uniprot id: A0A7H1PSC2
names: Similarity
messages: Belongs to the UPF0098 family.

146922:HEP81 RS13835
gene id: 146922:HEP81_RS13835
uniprot id: A0A7H1PYH5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

146922:HEP81 RS28340
gene id: 146922:HEP81_RS28340
uniprot id: A0A3R8WYA1
names: Caution
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS14215
gene id: 146922:HEP81_RS14215
uniprot id: A0A3R8Q8X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS26900
gene id: 146922:HEP81_RS26900
uniprot id: A0A7H1Q5T6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

146922:HEP81 RS29210
gene id: 146922:HEP81_RS29210
uniprot id: A0A7H1Q742
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

146922:HEP81 RS16155
gene id: 146922:HEP81_RS16155
uniprot id: A0A1X4GTK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

146922:HEP81 RS15495
gene id: 146922:HEP81_RS15495
uniprot id: A0A7H1PZF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS13775
gene id: 146922:HEP81_RS13775
uniprot id: A0A3R8RZ83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

146922:HEP81 RS29020
gene id: 146922:HEP81_RS29020
uniprot id: A0A3R8S6U7
names: Caution
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS12540
gene id: 146922:HEP81_RS12540
uniprot id: A0A1X4GVG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

146922:HEP81 RS18635
gene id: 146922:HEP81_RS18635
uniprot id: A0A7H1Q174
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

146922:HEP81 RS27225
gene id: 146922:HEP81_RS27225
uniprot id: A0A7H1Q5Z8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS19310
gene id: 146922:HEP81_RS19310
uniprot id: A0A1X4GRM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

146922:HEP81 RS39560
gene id: 146922:HEP81_RS39560
uniprot id: A0A7H1QCY5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS02970
gene id: 146922:HEP81_RS02970
uniprot id: A0A426RY54
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS15965
gene id: 146922:HEP81_RS15965
uniprot id: A0A7H1PZP6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

146922:HEP81 RS17495
gene id: 146922:HEP81_RS17495
uniprot id: A0A426RWD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS03290
gene id: 146922:HEP81_RS03290
uniprot id: A0A7H1PSG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS02940
gene id: 146922:HEP81_RS02940
uniprot id: A0A7H1PS96
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

146922:HEP81 RS02525
gene id: 146922:HEP81_RS02525
uniprot id: A0A7H1PS11
names: Similarity
messages: Belongs to the CdaR family.

146922:HEP81 RS15125
gene id: 146922:HEP81_RS15125
uniprot id: A0A426S1I8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

146922:HEP81 RS03735
gene id: 146922:HEP81_RS03735
uniprot id: A0A7H1PSQ5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

146922:HEP81 RS15585
gene id: 146922:HEP81_RS15585
uniprot id: A0A7H1PZH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

146922:HEP81 RS20460
gene id: 146922:HEP81_RS20460
uniprot id: A0A426S1V8
names: Similarity
messages: Belongs to the CsoR family.

146922:HEP81 RS09455
gene id: 146922:HEP81_RS09455
uniprot id: A0A7H1PW09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted

146922:HEP81 RS06865
gene id: 146922:HEP81_RS06865
uniprot id: A0A7H1PUI0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS30705
gene id: 146922:HEP81_RS30705
uniprot id: A0A1X4H3J8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

146922:HEP81 RS27895
gene id: 146922:HEP81_RS27895
uniprot id: A0A3R8WYF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

146922:HEP81 RS25800
gene id: 146922:HEP81_RS25800
uniprot id: A0A7H1Q572
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

146922:HEP81 RS31815
gene id: 146922:HEP81_RS31815
uniprot id: A0A7H1Q8K3
names: Similarity
messages: Belongs to the oxoprolinase family.

146922:HEP81 RS16450
gene id: 146922:HEP81_RS16450
uniprot id: A0A7H1PZZ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS31180
gene id: 146922:HEP81_RS31180
uniprot id: A0A7H1Q877
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

146922:HEP81 RS22390
gene id: 146922:HEP81_RS22390
uniprot id: A0A426RXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

146922:HEP81 RS16080
gene id: 146922:HEP81_RS16080
uniprot id: A0A1X4GTL1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

146922:HEP81 RS36370
gene id: 146922:HEP81_RS36370
uniprot id: A0A7H1QB69
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

146922:HEP81 RS03810
gene id: 146922:HEP81_RS03810
uniprot id: A0A7H1PSS0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

146922:HEP81 RS11510
gene id: 146922:HEP81_RS11510
uniprot id: A0A7H1PX67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

146922:HEP81 RS10275
gene id: 146922:HEP81_RS10275
uniprot id: A0A3R8RP14
names: Caution
names: Similarity
messages: Belongs to the thioesterase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS37320
gene id: 146922:HEP81_RS37320
uniprot id: A0A3R8SE66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

146922:HEP81 RS15670
gene id: 146922:HEP81_RS15670
uniprot id: A0A426S1J3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS36120
gene id: 146922:HEP81_RS36120
uniprot id: A0A7H1QB20
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS28335
gene id: 146922:HEP81_RS28335
uniprot id: A0A7H1Q6L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

146922:HEP81 RS16010
gene id: 146922:HEP81_RS16010
uniprot id: A0A1X4GTV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

146922:HEP81 RS11080
gene id: 146922:HEP81_RS11080
uniprot id: A0A7H1PWY5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS18405
gene id: 146922:HEP81_RS18405
uniprot id: A0A426SAM7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

146922:HEP81 RS12175
gene id: 146922:HEP81_RS12175
uniprot id: A0A1X4GVM9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

146922:HEP81 RS12750
gene id: 146922:HEP81_RS12750
uniprot id: A0A1X4GVA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS05630
gene id: 146922:HEP81_RS05630
uniprot id: A0A1X4GYD8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS31170
gene id: 146922:HEP81_RS31170
uniprot id: A0A1X4H3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

146922:HEP81 RS11880
gene id: 146922:HEP81_RS11880
uniprot id: A0A7H1PXE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS03850
gene id: 146922:HEP81_RS03850
uniprot id: A0A7H1PSS8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS05635
gene id: 146922:HEP81_RS05635
uniprot id: A0A7H1PTT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

146922:HEP81 RS27750
gene id: 146922:HEP81_RS27750
uniprot id: A0A1X4GMN3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS19360
gene id: 146922:HEP81_RS19360
uniprot id: A0A7H1Q1L8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS37800
gene id: 146922:HEP81_RS37800
uniprot id: A0A7H1QC02
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS35025
gene id: 146922:HEP81_RS35025
uniprot id: A0A426SC34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

146922:HEP81 RS21465
gene id: 146922:HEP81_RS21465
uniprot id: A0A7H1Q2R8
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

146922:HEP81 RS36995
gene id: 146922:HEP81_RS36995
uniprot id: A0A7H1QBJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

146922:HEP81 RS31610
gene id: 146922:HEP81_RS31610
uniprot id: A0A1X4H3R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

146922:HEP81 RS12065
gene id: 146922:HEP81_RS12065
uniprot id: A0A1X4GVW1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS21515
gene id: 146922:HEP81_RS21515
uniprot id: A0A426S2G5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

146922:HEP81 RS08780
gene id: 146922:HEP81_RS08780
uniprot id: A0A7H1PVM4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

146922:HEP81 RS05210
gene id: 146922:HEP81_RS05210
uniprot id: A0A3R8RGU1
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

146922:HEP81 RS14305
gene id: 146922:HEP81_RS14305
uniprot id: A0A426S3P7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

146922:HEP81 RS02275
gene id: 146922:HEP81_RS02275
uniprot id: A0A7H1PRW1
names: Similarity
messages: Belongs to the terpene synthase family. 2-methylisoborneol synthase subfamily.

146922:HEP81 RS25550
gene id: 146922:HEP81_RS25550
uniprot id: A0A1X4GNU2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

146922:HEP81 RS08235
gene id: 146922:HEP81_RS08235
uniprot id: A0A7H1PVB5
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

146922:HEP81 RS05215
gene id: 146922:HEP81_RS05215
uniprot id: A0A7H1PTK1
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

146922:HEP81 RS31435
gene id: 146922:HEP81_RS31435
uniprot id: A0A7H1Q8C8
names: Similarity
messages: Belongs to the barstar family.

146922:HEP81 RS34125
gene id: 146922:HEP81_RS34125
uniprot id: A0A7H1Q9W8
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

146922:HEP81 RS15855
gene id: 146922:HEP81_RS15855
uniprot id: A0A7H1PZM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS29510
gene id: 146922:HEP81_RS29510
uniprot id: A0A426SDY0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

146922:HEP81 RS17320
gene id: 146922:HEP81_RS17320
uniprot id: A0A7H1Q0F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

146922:HEP81 RS29930
gene id: 146922:HEP81_RS29930
uniprot id: A0A1X4GLL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

146922:HEP81 RS35865
gene id: 146922:HEP81_RS35865
uniprot id: A0A7H1QAW7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

146922:HEP81 RS16140
gene id: 146922:HEP81_RS16140
uniprot id: A0A1X4GTJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

146922:HEP81 RS24740
gene id: 146922:HEP81_RS24740
uniprot id: A0A7H1Q4L5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

146922:HEP81 RS25705
gene id: 146922:HEP81_RS25705
uniprot id: A0A426S5U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

146922:HEP81 RS19350
gene id: 146922:HEP81_RS19350
uniprot id: A0A1X4GRT5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

146922:HEP81 RS28910
gene id: 146922:HEP81_RS28910
uniprot id: A0A426SE82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

146922:HEP81 RS19965
gene id: 146922:HEP81_RS19965
uniprot id: A0A7H1Q1Y4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

146922:HEP81 RS12720
gene id: 146922:HEP81_RS12720
uniprot id: A0A7H1PXV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

146922:HEP81 RS20785
gene id: 146922:HEP81_RS20785
uniprot id: A0A7H1Q2D3
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

146922:HEP81 RS32835
gene id: 146922:HEP81_RS32835
uniprot id: A0A1X4H418
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS10980
gene id: 146922:HEP81_RS10980
uniprot id: A0A3R8RNF5
names: Subcellular Location Annotation
messages: Cytoplasm

146922:HEP81 RS04830
gene id: 146922:HEP81_RS04830
uniprot id: A0A7H1PTC4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

146922:HEP81 RS13840
gene id: 146922:HEP81_RS13840
uniprot id: A0A3R8RIS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

146922:HEP81 RS34845
gene id: 146922:HEP81_RS34845
uniprot id: A0A7H1QAB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

146922:HEP81 RS31190
gene id: 146922:HEP81_RS31190
uniprot id: A0A3R8S123
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

146922:HEP81 RS32250
gene id: 146922:HEP81_RS32250
uniprot id: A0A426RZC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS04855
gene id: 146922:HEP81_RS04855
uniprot id: A0A7H1PTC9
names: Cofactor
messages: Can also use Mn(2+) ion.

146922:HEP81 RS11520
gene id: 146922:HEP81_RS11520
uniprot id: A0A3R8R8X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

146922:HEP81 RS37610
gene id: 146922:HEP81_RS37610
uniprot id: A0A3R8RF03
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS10365
gene id: 146922:HEP81_RS10365
uniprot id: A0A1X4GW58
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

146922:HEP81 RS33705
gene id: 146922:HEP81_RS33705
uniprot id: A0A7H1Q9N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

146922:HEP81 RS17870
gene id: 146922:HEP81_RS17870
uniprot id: A0A7H1Q0R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

146922:HEP81 RS29005
gene id: 146922:HEP81_RS29005
uniprot id: A0A7H1Q701
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

146922:HEP81 RS05585
gene id: 146922:HEP81_RS05585
uniprot id: A0A7H1PTS7
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS19650
gene id: 146922:HEP81_RS19650
uniprot id: A0A7H1Q1S6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

146922:HEP81 RS09660
gene id: 146922:HEP81_RS09660
uniprot id: A0A7H1PW49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

146922:HEP81 RS39515
gene id: 146922:HEP81_RS39515
uniprot id: A0A7H1QCX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

146922:HEP81 RS39345
gene id: 146922:HEP81_RS39345
uniprot id: A0A7H1QCU9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

146922:HEP81 RS33595
gene id: 146922:HEP81_RS33595
uniprot id: A0A7H1Q9L1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS11785
gene id: 146922:HEP81_RS11785
uniprot id: A0A1X4GVU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS22455
gene id: 146922:HEP81_RS22455
uniprot id: A0A7H1Q3B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

146922:HEP81 RS36375
gene id: 146922:HEP81_RS36375
uniprot id: A0A7H1QB70
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

146922:HEP81 RS24040
gene id: 146922:HEP81_RS24040
uniprot id: A0A3R8SC50
names: Caution
names: Similarity
messages: Belongs to the ABC transporter superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS28295
gene id: 146922:HEP81_RS28295
uniprot id: A0A1X4GME9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

146922:HEP81 RS26620
gene id: 146922:HEP81_RS26620
uniprot id: A0A3R8QG88
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

146922:HEP81 RS08155
gene id: 146922:HEP81_RS08155
uniprot id: A0A7H1PV99
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS14965
gene id: 146922:HEP81_RS14965
uniprot id: A0A426S159
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

146922:HEP81 RS16535
gene id: 146922:HEP81_RS16535
uniprot id: A0A7H1Q007
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

146922:HEP81 RS22470
gene id: 146922:HEP81_RS22470
uniprot id: A0A7H1Q3C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

146922:HEP81 RS18175
gene id: 146922:HEP81_RS18175
uniprot id: A0A426SAQ3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

146922:HEP81 RS22600
gene id: 146922:HEP81_RS22600
uniprot id: A0A7H1Q3E7
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

146922:HEP81 RS24335
gene id: 146922:HEP81_RS24335
uniprot id: A0A7H1Q4D6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS01190
gene id: 146922:HEP81_RS01190
uniprot id: A0A7H1PR94
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS13630
gene id: 146922:HEP81_RS13630
uniprot id: A0A7H1PYD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S16 family.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

146922:HEP81 RS34360
gene id: 146922:HEP81_RS34360
uniprot id: A0A7H1QA15
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

146922:HEP81 RS37485
gene id: 146922:HEP81_RS37485
uniprot id: A0A7H1QBT9
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS39320
gene id: 146922:HEP81_RS39320
uniprot id: A0A7H1QCU4
names: Subcellular Location Annotation
messages: Peroxisome

146922:HEP81 RS28265
gene id: 146922:HEP81_RS28265
uniprot id: A0A7H1Q6K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

146922:HEP81 RS26895
gene id: 146922:HEP81_RS26895
uniprot id: A0A7H1Q5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

146922:HEP81 RS27330
gene id: 146922:HEP81_RS27330
uniprot id: A0A7H1Q619
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS04895
gene id: 146922:HEP81_RS04895
uniprot id: A0A7H1PTD7
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

146922:HEP81 RS25105
gene id: 146922:HEP81_RS25105
uniprot id: A0A7H1Q4T6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS32110
gene id: 146922:HEP81_RS32110
uniprot id: A0A7H1Q8Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

146922:HEP81 RS16050
gene id: 146922:HEP81_RS16050
uniprot id: A0A1X4GTC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

146922:HEP81 RS32760
gene id: 146922:HEP81_RS32760
uniprot id: A0A7H1Q943
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS32625
gene id: 146922:HEP81_RS32625
uniprot id: A0A7H1Q917
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS03380
gene id: 146922:HEP81_RS03380
uniprot id: A0A7H1PSI4
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS29815
gene id: 146922:HEP81_RS29815
uniprot id: A0A3R8SCS2
names: Similarity
messages: Belongs to the TlyA family.

146922:HEP81 RS22820
gene id: 146922:HEP81_RS22820
uniprot id: A0A7H1Q3J0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

146922:HEP81 RS04790
gene id: 146922:HEP81_RS04790
uniprot id: A0A7H1PTB6
names: Similarity
messages: Belongs to the CdaR family.

146922:HEP81 RS39350
gene id: 146922:HEP81_RS39350
uniprot id: A0A7H1QCV0
names: Similarity
messages: Belongs to the thioesterase family.

146922:HEP81 RS13865
gene id: 146922:HEP81_RS13865
uniprot id: A0A426S3E7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

146922:HEP81 RS34615
gene id: 146922:HEP81_RS34615
uniprot id: A0A7H1QA68
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

146922:HEP81 RS35930
gene id: 146922:HEP81_RS35930
uniprot id: A0A3R8WUV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

146922:HEP81 RS05860
gene id: 146922:HEP81_RS05860
uniprot id: A0A7H1PTY2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

146922:HEP81 RS16130
gene id: 146922:HEP81_RS16130
uniprot id: A0A1X4GTG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

146922:HEP81 RS30310
gene id: 146922:HEP81_RS30310
uniprot id: A0A7H1Q7R0
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

146922:HEP81 RS20805
gene id: 146922:HEP81_RS20805
uniprot id: A0A7H1Q2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS26805
gene id: 146922:HEP81_RS26805
uniprot id: A0A7H1Q5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS13255
gene id: 146922:HEP81_RS13255
uniprot id: A0A426S323
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

146922:HEP81 RS12725
gene id: 146922:HEP81_RS12725
uniprot id: A0A7H1PXV5
names: Similarity
messages: Belongs to the peptidase M1 family.

146922:HEP81 RS16435
gene id: 146922:HEP81_RS16435
uniprot id: A0A1X4GT84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

146922:HEP81 RS10460
gene id: 146922:HEP81_RS10460
uniprot id: A0A7H1PWK9
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS37715
gene id: 146922:HEP81_RS37715
uniprot id: A0A7H1QBY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS33065
gene id: 146922:HEP81_RS33065
uniprot id: A0A7H1Q9A4
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS05940
gene id: 146922:HEP81_RS05940
uniprot id: A0A3R8RDS8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS18935
gene id: 146922:HEP81_RS18935
uniprot id: A0A426SA58
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS18870
gene id: 146922:HEP81_RS18870
uniprot id: A0A7H1Q1C1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS26365
gene id: 146922:HEP81_RS26365
uniprot id: A0A7H1Q5I3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

146922:HEP81 RS35485
gene id: 146922:HEP81_RS35485
uniprot id: A0A7H1QAP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

146922:HEP81 RS05100
gene id: 146922:HEP81_RS05100
uniprot id: A0A1X4GYA8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS24900
gene id: 146922:HEP81_RS24900
uniprot id: A0A7H1Q4P4
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

146922:HEP81 RS16895
gene id: 146922:HEP81_RS16895
uniprot id: A0A7H1Q078
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS28060
gene id: 146922:HEP81_RS28060
uniprot id: A0A1X4GMS1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

146922:HEP81 RS00800
gene id: 146922:HEP81_RS00800
uniprot id: A0A7H1PR14
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS25405
gene id: 146922:HEP81_RS25405
uniprot id: A0A7H1Q4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS35075
gene id: 146922:HEP81_RS35075
uniprot id: A0A7H1QAG0
names: Similarity
messages: Belongs to the universal stress protein A family.

146922:HEP81 RS09355
gene id: 146922:HEP81_RS09355
uniprot id: A0A7H1PVY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

146922:HEP81 RS09085
gene id: 146922:HEP81_RS09085
uniprot id: A0A426SC17
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS13150
gene id: 146922:HEP81_RS13150
uniprot id: A0A7H1PY40
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS38595
gene id: 146922:HEP81_RS38595
uniprot id: A0A7H1QCF4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

146922:HEP81 RS10535
gene id: 146922:HEP81_RS10535
uniprot id: A0A3R8QK41
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

146922:HEP81 RS35665
gene id: 146922:HEP81_RS35665
uniprot id: A0A7H1QAS7
names: Similarity
messages: Belongs to the peptidase A31 family.

146922:HEP81 RS29375
gene id: 146922:HEP81_RS29375
uniprot id: A0A3R8QFC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS33385
gene id: 146922:HEP81_RS33385
uniprot id: A0A3R8SGL7
names: Subcellular Location Annotation
messages: Cytoplasm

146922:HEP81 RS34260
gene id: 146922:HEP81_RS34260
uniprot id: A0A1X4H4Z8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

146922:HEP81 RS26290
gene id: 146922:HEP81_RS26290
uniprot id: A0A3R8RJK2
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

146922:HEP81 RS11305
gene id: 146922:HEP81_RS11305
uniprot id: A0A7H1PX30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

146922:HEP81 RS05310
gene id: 146922:HEP81_RS05310
uniprot id: A0A7H1PTM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

146922:HEP81 RS33585
gene id: 146922:HEP81_RS33585
uniprot id: A0A1X4H4V2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

146922:HEP81 RS06275
gene id: 146922:HEP81_RS06275
uniprot id: A0A7H1PU65
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS26485
gene id: 146922:HEP81_RS26485
uniprot id: A0A7H1Q5K4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. Carboxylic acid reductase subfamily.
messages: Binds 1 phosphopantetheine covalently.
messages: Catalyzes the ATP- and NADPH-dependent reduction of carboxylic acids to the corresponding aldehydes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain likely catalyzes substrate activation by formation of an initial acyl-AMP intermediate, the central region contains the phosphopantetheine attachment site, and the C-terminal domain catalyzes the reduction by NADPH of the intermediate thioester formed from the attack of the phosphopantetheine thiol at the carbonyl carbon of acyl-AMP.

146922:HEP81 RS16665
gene id: 146922:HEP81_RS16665
uniprot id: A0A3R8R6M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS12490
gene id: 146922:HEP81_RS12490
uniprot id: A0A7H1PXQ7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS05955
gene id: 146922:HEP81_RS05955
uniprot id: A0A7H1PU01
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

146922:HEP81 RS27325
gene id: 146922:HEP81_RS27325
uniprot id: A0A7H1Q618
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

146922:HEP81 RS14150
gene id: 146922:HEP81_RS14150
uniprot id: A0A7H1PYN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS22475
gene id: 146922:HEP81_RS22475
uniprot id: A0A1X4GQ02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

146922:HEP81 RS16005
gene id: 146922:HEP81_RS16005
uniprot id: A0A1X4GTG0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

146922:HEP81 RS10935
gene id: 146922:HEP81_RS10935
uniprot id: A0A426SB75
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

146922:HEP81 RS25380
gene id: 146922:HEP81_RS25380
uniprot id: A0A7H1Q4Y9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

146922:HEP81 RS12110
gene id: 146922:HEP81_RS12110
uniprot id: A0A3R8WPV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

146922:HEP81 RS12925
gene id: 146922:HEP81_RS12925
uniprot id: A0A7H1PXZ5
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

146922:HEP81 RS15155
gene id: 146922:HEP81_RS15155
uniprot id: A0A1X4GTY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

146922:HEP81 RS31910
gene id: 146922:HEP81_RS31910
uniprot id: A0A7H1Q8L9
names: Similarity
messages: Belongs to the UPF0749 family.

146922:HEP81 RS26200
gene id: 146922:HEP81_RS26200
uniprot id: A0A7H1Q5F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

146922:HEP81 RS12085
gene id: 146922:HEP81_RS12085
uniprot id: A0A3R8Q721
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

146922:HEP81 RS33440
gene id: 146922:HEP81_RS33440
uniprot id: A0A7H1Q9I0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS14395
gene id: 146922:HEP81_RS14395
uniprot id: A0A7H1PYT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

146922:HEP81 RS19450
gene id: 146922:HEP81_RS19450
uniprot id: A0A7H1Q1N6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

146922:HEP81 RS18905
gene id: 146922:HEP81_RS18905
uniprot id: A0A7H1Q1C8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

146922:HEP81 RS19575
gene id: 146922:HEP81_RS19575
uniprot id: A0A7H1Q1R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

146922:HEP81 RS37400
gene id: 146922:HEP81_RS37400
uniprot id: A0A7H1QBS2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS36965
gene id: 146922:HEP81_RS36965
uniprot id: A0A7H1QBI9
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS16280
gene id: 146922:HEP81_RS16280
uniprot id: A0A3R8WQH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

146922:HEP81 RS14655
gene id: 146922:HEP81_RS14655
uniprot id: A0A1X4GTZ8
names: Similarity
messages: Belongs to the FBPase class 2 family.

146922:HEP81 RS07240
gene id: 146922:HEP81_RS07240
uniprot id: A0A7H1PUQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

146922:HEP81 RS11310
gene id: 146922:HEP81_RS11310
uniprot id: A0A7H1PX31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

146922:HEP81 RS10845
gene id: 146922:HEP81_RS10845
uniprot id: A0A3R8S3U6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

146922:HEP81 RS01555
gene id: 146922:HEP81_RS01555
uniprot id: A0A3R8QBF9
names: Similarity
messages: Belongs to the proline racemase family.

146922:HEP81 RS20450
gene id: 146922:HEP81_RS20450
uniprot id: A0A3R8S9T5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS16025
gene id: 146922:HEP81_RS16025
uniprot id: A0A426S1M8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

146922:HEP81 RS32070
gene id: 146922:HEP81_RS32070
uniprot id: A0A7H1Q8Q1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS19010
gene id: 146922:HEP81_RS19010
uniprot id: A0A7H1Q1F1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS14540
gene id: 146922:HEP81_RS14540
uniprot id: A0A3R8RZH0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS33505
gene id: 146922:HEP81_RS33505
uniprot id: A0A7H1Q9J3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS25195
gene id: 146922:HEP81_RS25195
uniprot id: A0A7H1Q4V4
names: Similarity
messages: Belongs to the TPP enzyme family.

146922:HEP81 RS05780
gene id: 146922:HEP81_RS05780
uniprot id: A0A7H1PTW5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

146922:HEP81 RS21645
gene id: 146922:HEP81_RS21645
uniprot id: A0A7H1Q2V4
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

146922:HEP81 RS33520
gene id: 146922:HEP81_RS33520
uniprot id: A0A7H1Q9J6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS27340
gene id: 146922:HEP81_RS27340
uniprot id: A0A7H1Q621
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

146922:HEP81 RS17615
gene id: 146922:HEP81_RS17615
uniprot id: A0A1X4H170
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

146922:HEP81 RS28675
gene id: 146922:HEP81_RS28675
uniprot id: A0A7H1Q6T6
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

146922:HEP81 RS38870
gene id: 146922:HEP81_RS38870
uniprot id: A0A7H1QCK8
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

146922:HEP81 RS03225
gene id: 146922:HEP81_RS03225
uniprot id: A0A426RY59
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

146922:HEP81 RS36190
gene id: 146922:HEP81_RS36190
uniprot id: A0A7H1QB33
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS30270
gene id: 146922:HEP81_RS30270
uniprot id: A0A7H1Q7Q2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS08785
gene id: 146922:HEP81_RS08785
uniprot id: A0A7H1PVM5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS20005
gene id: 146922:HEP81_RS20005
uniprot id: A0A7H1Q1Z0
names: Similarity
messages: Belongs to the GARS family.

146922:HEP81 RS20245
gene id: 146922:HEP81_RS20245
uniprot id: A0A426S9Q3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS16805
gene id: 146922:HEP81_RS16805
uniprot id: A0A7H1Q061
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

146922:HEP81 RS07245
gene id: 146922:HEP81_RS07245
uniprot id: A0A426RXZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

146922:HEP81 RS27955
gene id: 146922:HEP81_RS27955
uniprot id: A0A3R8QG92
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

146922:HEP81 RS08720
gene id: 146922:HEP81_RS08720
uniprot id: A0A7H1PVL2
names: Similarity
messages: Belongs to the IucA/IucC family.

146922:HEP81 RS17440
gene id: 146922:HEP81_RS17440
uniprot id: A0A3R8QBC2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS24215
gene id: 146922:HEP81_RS24215
uniprot id: A0A1X4GPF9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

146922:HEP81 RS14320
gene id: 146922:HEP81_RS14320
uniprot id: A0A7H1PYS0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

146922:HEP81 RS13280
gene id: 146922:HEP81_RS13280
uniprot id: A0A3R8RAG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

146922:HEP81 RS12545
gene id: 146922:HEP81_RS12545
uniprot id: A0A7H1PXR9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

146922:HEP81 RS18515
gene id: 146922:HEP81_RS18515
uniprot id: A0A7H1Q150
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS27290
gene id: 146922:HEP81_RS27290
uniprot id: A0A1X4GN42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

146922:HEP81 RS13265
gene id: 146922:HEP81_RS13265
uniprot id: A0A7H1PY63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

146922:HEP81 RS13345
gene id: 146922:HEP81_RS13345
uniprot id: A0A3R8RAH6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

146922:HEP81 RS28000
gene id: 146922:HEP81_RS28000
uniprot id: A0A3R8QLU9
names: Similarity
messages: Belongs to the peptidase C40 family.

146922:HEP81 RS28485
gene id: 146922:HEP81_RS28485
uniprot id: A0A7H1Q6P7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS22730
gene id: 146922:HEP81_RS22730
uniprot id: A0A7H1Q3H2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

146922:HEP81 RS29705
gene id: 146922:HEP81_RS29705
uniprot id: A0A7H1Q7E1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

146922:HEP81 RS30725
gene id: 146922:HEP81_RS30725
uniprot id: A0A7H1Q7Z3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

146922:HEP81 RS22360
gene id: 146922:HEP81_RS22360
uniprot id: A0A7H1Q399
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

146922:HEP81 RS12775
gene id: 146922:HEP81_RS12775
uniprot id: A0A1X4GV28
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

146922:HEP81 RS14740
gene id: 146922:HEP81_RS14740
uniprot id: A0A7H1PZ05
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS01225
gene id: 146922:HEP81_RS01225
uniprot id: A0A7H1PRA1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS39000
gene id: 146922:HEP81_RS39000
uniprot id: A0A7H1PQP9
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS09745
gene id: 146922:HEP81_RS09745
uniprot id: A0A426SBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS32785
gene id: 146922:HEP81_RS32785
uniprot id: A0A3R8RGJ2
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS05865
gene id: 146922:HEP81_RS05865
uniprot id: A0A3R8RDT7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS21420
gene id: 146922:HEP81_RS21420
uniprot id: A0A7H1Q2Q9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

146922:HEP81 RS16170
gene id: 146922:HEP81_RS16170
uniprot id: A0A1X4GTS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

146922:HEP81 RS27805
gene id: 146922:HEP81_RS27805
uniprot id: A0A1X4GMM4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

146922:HEP81 RS36105
gene id: 146922:HEP81_RS36105
uniprot id: A0A426S944
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS36620
gene id: 146922:HEP81_RS36620
uniprot id: A0A7H1QBB8
names: Similarity
messages: Belongs to the AHA1 family.

146922:HEP81 RS17330
gene id: 146922:HEP81_RS17330
uniprot id: A0A7H1Q0F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS03100
gene id: 146922:HEP81_RS03100
uniprot id: A0A7H1PSC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

146922:HEP81 RS20275
gene id: 146922:HEP81_RS20275
uniprot id: A0A7H1Q234
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

146922:HEP81 RS39665
gene id: 146922:HEP81_RS39665
uniprot id: A0A7H1QD06
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS33010
gene id: 146922:HEP81_RS33010
uniprot id: A0A3R8RWW2
names: Subunit
messages: Homodimer.

146922:HEP81 RS31575
gene id: 146922:HEP81_RS31575
uniprot id: A0A7H1Q8F5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

146922:HEP81 RS23770
gene id: 146922:HEP81_RS23770
uniprot id: A0A7H1Q431
names: Similarity
messages: Belongs to the phosphohexose mutase family.

146922:HEP81 RS21410
gene id: 146922:HEP81_RS21410
uniprot id: A0A7H1Q2Q7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

146922:HEP81 RS14445
gene id: 146922:HEP81_RS14445
uniprot id: A0A3R8RZG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS19655
gene id: 146922:HEP81_RS19655
uniprot id: A0A7H1Q1S7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS11650
gene id: 146922:HEP81_RS11650
uniprot id: A0A1X4GVJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

146922:HEP81 RS13025
gene id: 146922:HEP81_RS13025
uniprot id: A0A7H1PY15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

146922:HEP81 RS31360
gene id: 146922:HEP81_RS31360
uniprot id: A0A7H1Q8B3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

146922:HEP81 RS31370
gene id: 146922:HEP81_RS31370
uniprot id: A0A1X4H3G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

146922:HEP81 RS25675
gene id: 146922:HEP81_RS25675
uniprot id: A0A1X4GNS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

146922:HEP81 RS22170
gene id: 146922:HEP81_RS22170
uniprot id: A0A7H1Q361
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

146922:HEP81 RS16075
gene id: 146922:HEP81_RS16075
uniprot id: A0A1X4GTS9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

146922:HEP81 RS24605
gene id: 146922:HEP81_RS24605
uniprot id: A0A7H1Q4J0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

146922:HEP81 RS28120
gene id: 146922:HEP81_RS28120
uniprot id: A0A3R8RHK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

146922:HEP81 RS30475
gene id: 146922:HEP81_RS30475
uniprot id: A0A1X4H3G6
names: Caution
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS11975
gene id: 146922:HEP81_RS11975
uniprot id: A0A3R8WPU6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

146922:HEP81 RS16630
gene id: 146922:HEP81_RS16630
uniprot id: A0A7H1Q026
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS39735
gene id: 146922:HEP81_RS39735
uniprot id: A0A7H1QD20
names: Similarity
messages: Belongs to the ParB family.

146922:HEP81 RS23695
gene id: 146922:HEP81_RS23695
uniprot id: A0A7H1Q416
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

146922:HEP81 RS12910
gene id: 146922:HEP81_RS12910
uniprot id: A0A7H1PXZ2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS29405
gene id: 146922:HEP81_RS29405
uniprot id: A0A426SDY2
names: Similarity
messages: Belongs to the CobH/CbiC family.

146922:HEP81 RS10855
gene id: 146922:HEP81_RS10855
uniprot id: A0A7H1PWU0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS23785
gene id: 146922:HEP81_RS23785
uniprot id: A0A7H1Q434
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS15295
gene id: 146922:HEP81_RS15295
uniprot id: A0A7H1PZB3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

146922:HEP81 RS19290
gene id: 146922:HEP81_RS19290
uniprot id: A0A3R8SEL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

146922:HEP81 RS05885
gene id: 146922:HEP81_RS05885
uniprot id: A0A7H1PTY7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

146922:HEP81 RS11175
gene id: 146922:HEP81_RS11175
uniprot id: A0A7H1PX05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS17695
gene id: 146922:HEP81_RS17695
uniprot id: A0A7H1Q0N4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

146922:HEP81 RS16660
gene id: 146922:HEP81_RS16660
uniprot id: A0A7H1Q032
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

146922:HEP81 RS20855
gene id: 146922:HEP81_RS20855
uniprot id: A0A7H1Q2E7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS28535
gene id: 146922:HEP81_RS28535
uniprot id: A0A3R8SHB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

146922:HEP81 RS29700
gene id: 146922:HEP81_RS29700
uniprot id: A0A426SDK8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS14230
gene id: 146922:HEP81_RS14230
uniprot id: A0A7H1PYQ2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS28315
gene id: 146922:HEP81_RS28315
uniprot id: A0A1X4GMM1
names: Similarity
messages: Belongs to the YggT family.

146922:HEP81 RS18140
gene id: 146922:HEP81_RS18140
uniprot id: A0A7H1Q0X2
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

146922:HEP81 RS27800
gene id: 146922:HEP81_RS27800
uniprot id: A0A7H1Q6B1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

146922:HEP81 RS36290
gene id: 146922:HEP81_RS36290
uniprot id: A0A7H1QB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS15000
gene id: 146922:HEP81_RS15000
uniprot id: A0A7H1PZ55
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

146922:HEP81 RS32190
gene id: 146922:HEP81_RS32190
uniprot id: A0A7H1Q8S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

146922:HEP81 RS19445
gene id: 146922:HEP81_RS19445
uniprot id: A0A7H1Q1N5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS17060
gene id: 146922:HEP81_RS17060
uniprot id: A0A426RW11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

146922:HEP81 RS03650
gene id: 146922:HEP81_RS03650
uniprot id: A0A7H1PSN8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

146922:HEP81 RS33725
gene id: 146922:HEP81_RS33725
uniprot id: A0A7H1Q9N7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS15995
gene id: 146922:HEP81_RS15995
uniprot id: A0A7H1PZQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

146922:HEP81 RS30660
gene id: 146922:HEP81_RS30660
uniprot id: A0A7H1Q7Y0
names: Similarity
messages: Belongs to the glutamine synthetase family.

146922:HEP81 RS35130
gene id: 146922:HEP81_RS35130
uniprot id: A0A7H1QAH1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS19665
gene id: 146922:HEP81_RS19665
uniprot id: A0A7H1Q1S9
names: Similarity
messages: Belongs to the SCO1/2 family.

146922:HEP81 RS36540
gene id: 146922:HEP81_RS36540
uniprot id: A0A7H1QBA2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS13905
gene id: 146922:HEP81_RS13905
uniprot id: A0A7H1PYI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

146922:HEP81 RS15195
gene id: 146922:HEP81_RS15195
uniprot id: A0A426S1B0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS07800
gene id: 146922:HEP81_RS07800
uniprot id: A0A7H1PV26
names: Similarity
messages: Belongs to the peptidase C40 family.

146922:HEP81 RS35805
gene id: 146922:HEP81_RS35805
uniprot id: A0A7H1QAV5
names: Similarity
messages: Belongs to the universal stress protein A family.

146922:HEP81 RS20755
gene id: 146922:HEP81_RS20755
uniprot id: A0A7H1Q2C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

146922:HEP81 RS14825
gene id: 146922:HEP81_RS14825
uniprot id: A0A7H1PZ23
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

146922:HEP81 RS34580
gene id: 146922:HEP81_RS34580
uniprot id: A0A7H1QA61
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

146922:HEP81 RS16235
gene id: 146922:HEP81_RS16235
uniprot id: A0A1X4GT90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

146922:HEP81 RS36875
gene id: 146922:HEP81_RS36875
uniprot id: A0A7H1QBH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

146922:HEP81 RS38170
gene id: 146922:HEP81_RS38170
uniprot id: A0A426RWR9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS24180
gene id: 146922:HEP81_RS24180
uniprot id: A0A1X4GPI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS06265
gene id: 146922:HEP81_RS06265
uniprot id: A0A426S4A5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

146922:HEP81 RS37010
gene id: 146922:HEP81_RS37010
uniprot id: A0A7H1QBJ8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS11275
gene id: 146922:HEP81_RS11275
uniprot id: A0A7H1PX24
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

146922:HEP81 RS28280
gene id: 146922:HEP81_RS28280
uniprot id: A0A3R8QFS2
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS23545
gene id: 146922:HEP81_RS23545
uniprot id: A0A7H1Q3Y6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS07070
gene id: 146922:HEP81_RS07070
uniprot id: A0A3R8Q701
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

146922:HEP81 RS38580
gene id: 146922:HEP81_RS38580
uniprot id: A0A7H1QCF1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

146922:HEP81 RS30965
gene id: 146922:HEP81_RS30965
uniprot id: A0A7H1Q840
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS07050
gene id: 146922:HEP81_RS07050
uniprot id: A0A7H1PUL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

146922:HEP81 RS09490
gene id: 146922:HEP81_RS09490
uniprot id: A0A7H1PW16
names: Similarity
messages: Belongs to the terpene synthase family.

146922:HEP81 RS39110
gene id: 146922:HEP81_RS39110
uniprot id: A0A7H1QCQ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS10265
gene id: 146922:HEP81_RS10265
uniprot id: A0A7H1PWH0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS31405
gene id: 146922:HEP81_RS31405
uniprot id: A0A3R8REL4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

146922:HEP81 RS25610
gene id: 146922:HEP81_RS25610
uniprot id: A0A7H1Q535
names: Similarity
messages: Belongs to the FPG family.

146922:HEP81 RS30520
gene id: 146922:HEP81_RS30520
uniprot id: A0A426S6M6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

146922:HEP81 RS24015
gene id: 146922:HEP81_RS24015
uniprot id: A0A3R8RE24
names: Similarity
messages: Belongs to the peptidase C56 family.

146922:HEP81 RS33265
gene id: 146922:HEP81_RS33265
uniprot id: A0A7H1Q9E4
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS25545
gene id: 146922:HEP81_RS25545
uniprot id: A0A7H1Q522
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

146922:HEP81 RS32675
gene id: 146922:HEP81_RS32675
uniprot id: A0A7H1Q926
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

146922:HEP81 RS23605
gene id: 146922:HEP81_RS23605
uniprot id: A0A1X4H0N8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS15435
gene id: 146922:HEP81_RS15435
uniprot id: A0A7H1PZE0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

146922:HEP81 RS25850
gene id: 146922:HEP81_RS25850
uniprot id: A0A7H1Q582
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

146922:HEP81 RS27970
gene id: 146922:HEP81_RS27970
uniprot id: A0A3R8WYE1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS37235
gene id: 146922:HEP81_RS37235
uniprot id: A0A7H1QBN9
names: Similarity
messages: Belongs to the darcynin family.

146922:HEP81 RS25665
gene id: 146922:HEP81_RS25665
uniprot id: A0A7H1Q544
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

146922:HEP81 RS29340
gene id: 146922:HEP81_RS29340
uniprot id: A0A7H1Q768
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

146922:HEP81 RS01790
gene id: 146922:HEP81_RS01790
uniprot id: A0A7H1PRL2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

146922:HEP81 RS36415
gene id: 146922:HEP81_RS36415
uniprot id: A0A7H1QB78
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

146922:HEP81 RS04860
gene id: 146922:HEP81_RS04860
uniprot id: A0A7H1PTD0
names: Similarity
messages: Belongs to the malate synthase family.

146922:HEP81 RS39445
gene id: 146922:HEP81_RS39445
uniprot id: A0A7H1QCW3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

146922:HEP81 RS27960
gene id: 146922:HEP81_RS27960
uniprot id: A0A1X4GN06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

146922:HEP81 RS16160
gene id: 146922:HEP81_RS16160
uniprot id: A0A1X4GTA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

146922:HEP81 RS09550
gene id: 146922:HEP81_RS09550
uniprot id: A0A7H1PW27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS08775
gene id: 146922:HEP81_RS08775
uniprot id: A0A1X4GXC8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

146922:HEP81 RS38060
gene id: 146922:HEP81_RS38060
uniprot id: A0A7H1QC54
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

146922:HEP81 RS08570
gene id: 146922:HEP81_RS08570
uniprot id: A0A7H1PVI2
names: Similarity
messages: Belongs to the malate synthase family.

146922:HEP81 RS15545
gene id: 146922:HEP81_RS15545
uniprot id: A0A7H1PZG2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

146922:HEP81 RS11145
gene id: 146922:HEP81_RS11145
uniprot id: A0A7H1PWZ8
names: Similarity
messages: Belongs to the IucA/IucC family.

146922:HEP81 RS13315
gene id: 146922:HEP81_RS13315
uniprot id: A0A1X4GV88
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

146922:HEP81 RS36285
gene id: 146922:HEP81_RS36285
uniprot id: A0A7H1QB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS19970
gene id: 146922:HEP81_RS19970
uniprot id: A0A7H1Q1Y5
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

146922:HEP81 RS18170
gene id: 146922:HEP81_RS18170
uniprot id: A0A7H1Q0X8
names: Subunit
messages: Homodimer.

146922:HEP81 RS02735
gene id: 146922:HEP81_RS02735
uniprot id: A0A7H1PS54
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

146922:HEP81 RS12495
gene id: 146922:HEP81_RS12495
uniprot id: A0A3R8RH87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

146922:HEP81 RS06750
gene id: 146922:HEP81_RS06750
uniprot id: A0A7H1PUF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

146922:HEP81 RS21400
gene id: 146922:HEP81_RS21400
uniprot id: A0A7H1Q2Q5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS31590
gene id: 146922:HEP81_RS31590
uniprot id: A0A1X4H3K3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

146922:HEP81 RS03550
gene id: 146922:HEP81_RS03550
uniprot id: A0A7H1PSL8
names: Similarity
messages: Belongs to the thioesterase family.

146922:HEP81 RS05375
gene id: 146922:HEP81_RS05375
uniprot id: A0A7H1PTN5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS25535
gene id: 146922:HEP81_RS25535
uniprot id: A0A7H1Q520
names: Similarity
messages: Belongs to the peptidase M1 family.

146922:HEP81 RS28765
gene id: 146922:HEP81_RS28765
uniprot id: A0A7H1Q6V3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

146922:HEP81 RS26890
gene id: 146922:HEP81_RS26890
uniprot id: A0A7H1Q5T4
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS10450
gene id: 146922:HEP81_RS10450
uniprot id: A0A7H1PWK7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

146922:HEP81 RS03045
gene id: 146922:HEP81_RS03045
uniprot id: A0A3R8Q5X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS02695
gene id: 146922:HEP81_RS02695
uniprot id: A0A7H1PS46
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS31945
gene id: 146922:HEP81_RS31945
uniprot id: A0A7H1Q8M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

146922:HEP81 RS13030
gene id: 146922:HEP81_RS13030
uniprot id: A0A3R8WRA2
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

146922:HEP81 RS19280
gene id: 146922:HEP81_RS19280
uniprot id: A0A7H1Q1K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

146922:HEP81 RS24890
gene id: 146922:HEP81_RS24890
uniprot id: A0A7H1Q4P2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

146922:HEP81 RS10940
gene id: 146922:HEP81_RS10940
uniprot id: A0A7H1PWV7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

146922:HEP81 RS06410
gene id: 146922:HEP81_RS06410
uniprot id: A0A7H1PU93
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS25580
gene id: 146922:HEP81_RS25580
uniprot id: A0A7H1Q529
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS12850
gene id: 146922:HEP81_RS12850
uniprot id: A0A426S0W2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

146922:HEP81 RS12980
gene id: 146922:HEP81_RS12980
uniprot id: A0A7H1PY06
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS27085
gene id: 146922:HEP81_RS27085
uniprot id: A0A7H1Q5X2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS07080
gene id: 146922:HEP81_RS07080
uniprot id: A0A7H1PUM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

146922:HEP81 RS28475
gene id: 146922:HEP81_RS28475
uniprot id: A0A3R8QFQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

146922:HEP81 RS15320
gene id: 146922:HEP81_RS15320
uniprot id: A0A7H1PZB8
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

146922:HEP81 RS29945
gene id: 146922:HEP81_RS29945
uniprot id: A0A1X4GM02
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS15645
gene id: 146922:HEP81_RS15645
uniprot id: A0A3R8QDJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

146922:HEP81 RS36785
gene id: 146922:HEP81_RS36785
uniprot id: A0A7H1QBF4
names: Similarity
messages: Belongs to the universal stress protein A family.

146922:HEP81 RS28305
gene id: 146922:HEP81_RS28305
uniprot id: A0A7H1Q6L1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

146922:HEP81 RS39440
gene id: 146922:HEP81_RS39440
uniprot id: A0A7H1QCW2
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS35185
gene id: 146922:HEP81_RS35185
uniprot id: A0A7H1QAI2
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

146922:HEP81 RS27725
gene id: 146922:HEP81_RS27725
uniprot id: A0A1X4GMP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

146922:HEP81 RS29075
gene id: 146922:HEP81_RS29075
uniprot id: A0A7H1Q715
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS25670
gene id: 146922:HEP81_RS25670
uniprot id: A0A3R8RKC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS17015
gene id: 146922:HEP81_RS17015
uniprot id: A0A7H1Q0A0
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

146922:HEP81 RS20020
gene id: 146922:HEP81_RS20020
uniprot id: A0A7H1Q1Z3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

146922:HEP81 RS32825
gene id: 146922:HEP81_RS32825
uniprot id: A0A7H1Q956
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS08455
gene id: 146922:HEP81_RS08455
uniprot id: A0A7H1PVF9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

146922:HEP81 RS14360
gene id: 146922:HEP81_RS14360
uniprot id: A0A7H1PYS8
names: Similarity
messages: Belongs to the UPF0162 family.

146922:HEP81 RS30875
gene id: 146922:HEP81_RS30875
uniprot id: A0A7H1Q822
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS28665
gene id: 146922:HEP81_RS28665
uniprot id: A0A7H1Q6T4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS18710
gene id: 146922:HEP81_RS18710
uniprot id: A0A7H1Q189
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

146922:HEP81 RS15775
gene id: 146922:HEP81_RS15775
uniprot id: A0A7H1PZK8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

146922:HEP81 RS35445
gene id: 146922:HEP81_RS35445
uniprot id: A0A1X4H5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

146922:HEP81 RS30385
gene id: 146922:HEP81_RS30385
uniprot id: A0A7H1Q7S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

146922:HEP81 RS13115
gene id: 146922:HEP81_RS13115
uniprot id: A0A7H1PY33
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS06015
gene id: 146922:HEP81_RS06015
uniprot id: A0A1X4H227
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

146922:HEP81 RS26320
gene id: 146922:HEP81_RS26320
uniprot id: A0A7H1Q5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS18215
gene id: 146922:HEP81_RS18215
uniprot id: A0A426SAM9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS21110
gene id: 146922:HEP81_RS21110
uniprot id: A0A7H1Q2J7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS22140
gene id: 146922:HEP81_RS22140
uniprot id: A0A7H1Q355
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS06625
gene id: 146922:HEP81_RS06625
uniprot id: A0A7H1PUD2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

146922:HEP81 RS17970
gene id: 146922:HEP81_RS17970
uniprot id: A0A7H1Q0T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

146922:HEP81 RS03670
gene id: 146922:HEP81_RS03670
uniprot id: A0A3R8RAS9
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS34635
gene id: 146922:HEP81_RS34635
uniprot id: A0A7H1QA72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

146922:HEP81 RS27600
gene id: 146922:HEP81_RS27600
uniprot id: A0A3R8RHQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS25080
gene id: 146922:HEP81_RS25080
uniprot id: A0A3R8RK15
names: Similarity
messages: Belongs to the YciI family.

146922:HEP81 RS38970
gene id: 146922:HEP81_RS38970
uniprot id: A0A7H1QCN1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS08965
gene id: 146922:HEP81_RS08965
uniprot id: A0A7H1PVR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

146922:HEP81 RS37465
gene id: 146922:HEP81_RS37465
uniprot id: A0A7H1QBT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS11280
gene id: 146922:HEP81_RS11280
uniprot id: A0A1X4GW92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS12435
gene id: 146922:HEP81_RS12435
uniprot id: A0A7H1PXP6
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

146922:HEP81 RS26250
gene id: 146922:HEP81_RS26250
uniprot id: A0A7H1Q5G0
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS37110
gene id: 146922:HEP81_RS37110
uniprot id: A0A7H1QBL6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

146922:HEP81 RS35555
gene id: 146922:HEP81_RS35555
uniprot id: A0A7H1QAQ6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

146922:HEP81 RS09405
gene id: 146922:HEP81_RS09405
uniprot id: A0A7H1PVZ9
names: Similarity
messages: Belongs to the ketopantoate reductase family.

146922:HEP81 RS04950
gene id: 146922:HEP81_RS04950
uniprot id: A0A7H1PTE8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

146922:HEP81 RS28465
gene id: 146922:HEP81_RS28465
uniprot id: A0A3R8RQL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

146922:HEP81 RS22240
gene id: 146922:HEP81_RS22240
uniprot id: A0A7H1Q374
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS15075
gene id: 146922:HEP81_RS15075
uniprot id: A0A7H1PZ70
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

146922:HEP81 RS24665
gene id: 146922:HEP81_RS24665
uniprot id: A0A426S5K2
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

146922:HEP81 RS03285
gene id: 146922:HEP81_RS03285
uniprot id: A0A7H1PSG5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

146922:HEP81 RS27260
gene id: 146922:HEP81_RS27260
uniprot id: A0A7H1Q605
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

146922:HEP81 RS28745
gene id: 146922:HEP81_RS28745
uniprot id: A0A1X4GM67
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS18305
gene id: 146922:HEP81_RS18305
uniprot id: A0A7H1Q106
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS29790
gene id: 146922:HEP81_RS29790
uniprot id: A0A7H1Q7F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

146922:HEP81 RS25145
gene id: 146922:HEP81_RS25145
uniprot id: A0A7H1Q4U4
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

146922:HEP81 RS24830
gene id: 146922:HEP81_RS24830
uniprot id: A0A7H1Q4N1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

146922:HEP81 RS16385
gene id: 146922:HEP81_RS16385
uniprot id: A0A1X4GTP6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

146922:HEP81 RS29055
gene id: 146922:HEP81_RS29055
uniprot id: A0A7H1Q711
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

146922:HEP81 RS24165
gene id: 146922:HEP81_RS24165
uniprot id: A0A1X4GPZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

146922:HEP81 RS15570
gene id: 146922:HEP81_RS15570
uniprot id: A0A7H1PZG7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

146922:HEP81 RS29680
gene id: 146922:HEP81_RS29680
uniprot id: A0A3R8QL92
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

146922:HEP81 RS37895
gene id: 146922:HEP81_RS37895
uniprot id: A0A7H1QC21
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

146922:HEP81 RS32340
gene id: 146922:HEP81_RS32340
uniprot id: A0A1X4H4J1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

146922:HEP81 RS02370
gene id: 146922:HEP81_RS02370
uniprot id: A0A7H1PRY1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

146922:HEP81 RS32310
gene id: 146922:HEP81_RS32310
uniprot id: A0A7H1Q8U8
names: Similarity
messages: Belongs to the IMPACT family.

146922:HEP81 RS28050
gene id: 146922:HEP81_RS28050
uniprot id: A0A7H1Q6G1
names: Similarity
messages: Belongs to the arsA ATPase family.

146922:HEP81 RS04880
gene id: 146922:HEP81_RS04880
uniprot id: A0A7H1PTD4
names: Similarity
messages: Belongs to the citrate synthase family.

146922:HEP81 RS06780
gene id: 146922:HEP81_RS06780
uniprot id: A0A426S479
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

146922:HEP81 RS31120
gene id: 146922:HEP81_RS31120
uniprot id: A0A7H1Q865
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS05255
gene id: 146922:HEP81_RS05255
uniprot id: A0A7H1PTL1
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

146922:HEP81 RS31605
gene id: 146922:HEP81_RS31605
uniprot id: A0A7H1Q8G1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS23805
gene id: 146922:HEP81_RS23805
uniprot id: A0A7H1Q438
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS04110
gene id: 146922:HEP81_RS04110
uniprot id: A0A7H1PSX8
names: Similarity
messages: Belongs to the cytochrome P450 family.

146922:HEP81 RS37830
gene id: 146922:HEP81_RS37830
uniprot id: A0A7H1QC08
names: Similarity
messages: Belongs to the peptidase S1 family.

146922:HEP81 RS31295
gene id: 146922:HEP81_RS31295
uniprot id: A0A1X4H3V9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS25095
gene id: 146922:HEP81_RS25095
uniprot id: A0A7H1Q4T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

146922:HEP81 RS32020
gene id: 146922:HEP81_RS32020
uniprot id: A0A7H1Q8P1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

146922:HEP81 RS15620
gene id: 146922:HEP81_RS15620
uniprot id: A0A1X4GU21
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

146922:HEP81 RS12860
gene id: 146922:HEP81_RS12860
uniprot id: A0A7H1PXY2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

146922:HEP81 RS10885
gene id: 146922:HEP81_RS10885
uniprot id: A0A7H1PWU6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS32715
gene id: 146922:HEP81_RS32715
uniprot id: A0A7H1Q934
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS13530
gene id: 146922:HEP81_RS13530
uniprot id: A0A7H1PYB5
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS20510
gene id: 146922:HEP81_RS20510
uniprot id: A0A1X4GR76
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

146922:HEP81 RS05775
gene id: 146922:HEP81_RS05775
uniprot id: A0A7H1PTW4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS37615
gene id: 146922:HEP81_RS37615
uniprot id: A0A7H1QBW5
names: Similarity
messages: Belongs to the thioesterase family.

146922:HEP81 RS15720
gene id: 146922:HEP81_RS15720
uniprot id: A0A7H1PZJ6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS09805
gene id: 146922:HEP81_RS09805
uniprot id: A0A426SB97
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

146922:HEP81 RS04455
gene id: 146922:HEP81_RS04455
uniprot id: A0A7H1PT49
names: Similarity
messages: Belongs to the FPG family.

146922:HEP81 RS10390
gene id: 146922:HEP81_RS10390
uniprot id: A0A7H1PWJ5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

146922:HEP81 RS30855
gene id: 146922:HEP81_RS30855
uniprot id: A0A7H1Q818
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS29170
gene id: 146922:HEP81_RS29170
uniprot id: A0A1X4GM10
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

146922:HEP81 RS08620
gene id: 146922:HEP81_RS08620
uniprot id: A0A7H1PVJ2
names: Similarity
messages: Belongs to the glutamate synthase family.

146922:HEP81 RS34290
gene id: 146922:HEP81_RS34290
uniprot id: A0A7H1QA01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS24010
gene id: 146922:HEP81_RS24010
uniprot id: A0A426S4W3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS26110
gene id: 146922:HEP81_RS26110
uniprot id: A0A1X4GNJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

146922:HEP81 RS03930
gene id: 146922:HEP81_RS03930
uniprot id: A0A7H1PSU3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

146922:HEP81 RS20620
gene id: 146922:HEP81_RS20620
uniprot id: A0A1X4GQZ1
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

146922:HEP81 RS28840
gene id: 146922:HEP81_RS28840
uniprot id: A0A1X4GMD8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

146922:HEP81 RS24505
gene id: 146922:HEP81_RS24505
uniprot id: A0A7H1Q4G9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

146922:HEP81 RS31520
gene id: 146922:HEP81_RS31520
uniprot id: A0A7H1Q8E5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

146922:HEP81 RS18830
gene id: 146922:HEP81_RS18830
uniprot id: A0A426SA97
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

146922:HEP81 RS26030
gene id: 146922:HEP81_RS26030
uniprot id: A0A7H1Q5B6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

146922:HEP81 RS11025
gene id: 146922:HEP81_RS11025
uniprot id: A0A7H1PWX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

146922:HEP81 RS16740
gene id: 146922:HEP81_RS16740
uniprot id: A0A1X4GSX0
names: Subcellular Location Annotation
messages: Cytoplasm

146922:HEP81 RS30505
gene id: 146922:HEP81_RS30505
uniprot id: A0A426S6N3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

146922:HEP81 RS26680
gene id: 146922:HEP81_RS26680
uniprot id: A0A7H1Q5P4
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS38300
gene id: 146922:HEP81_RS38300
uniprot id: A0A7H1QC99
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

146922:HEP81 RS16315
gene id: 146922:HEP81_RS16315
uniprot id: A0A7H1PZW5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

146922:HEP81 RS03665
gene id: 146922:HEP81_RS03665
uniprot id: A0A7H1PSP1
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS11790
gene id: 146922:HEP81_RS11790
uniprot id: A0A7H1PXC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS23430
gene id: 146922:HEP81_RS23430
uniprot id: A0A3R8QB72
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

146922:HEP81 RS22050
gene id: 146922:HEP81_RS22050
uniprot id: A0A7H1Q337
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS27925
gene id: 146922:HEP81_RS27925
uniprot id: A0A426SEP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

146922:HEP81 RS39500
gene id: 146922:HEP81_RS39500
uniprot id: A0A7H1QCX3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

146922:HEP81 RS29270
gene id: 146922:HEP81_RS29270
uniprot id: A0A7H1Q754
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

146922:HEP81 RS25205
gene id: 146922:HEP81_RS25205
uniprot id: A0A7H1Q4V6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS03685
gene id: 146922:HEP81_RS03685
uniprot id: A0A7H1PSP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS03675
gene id: 146922:HEP81_RS03675
uniprot id: A0A7H1PSP3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

146922:HEP81 RS28740
gene id: 146922:HEP81_RS28740
uniprot id: A0A7H1Q6U8
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS16085
gene id: 146922:HEP81_RS16085
uniprot id: A0A426S1I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

146922:HEP81 RS29895
gene id: 146922:HEP81_RS29895
uniprot id: A0A3R8QH37
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

146922:HEP81 RS16485
gene id: 146922:HEP81_RS16485
uniprot id: A0A426S1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

146922:HEP81 RS34300
gene id: 146922:HEP81_RS34300
uniprot id: A0A7H1QA03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

146922:HEP81 RS16760
gene id: 146922:HEP81_RS16760
uniprot id: A0A7H1Q052
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

146922:HEP81 RS23395
gene id: 146922:HEP81_RS23395
uniprot id: A0A7H1Q3V6
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

146922:HEP81 RS01880
gene id: 146922:HEP81_RS01880
uniprot id: A0A7H1PRN0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

146922:HEP81 RS26635
gene id: 146922:HEP81_RS26635
uniprot id: A0A7H1Q5N5
names: Similarity
messages: Belongs to the pirin family.

146922:HEP81 RS28450
gene id: 146922:HEP81_RS28450
uniprot id: A0A426SE94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

146922:HEP81 RS16120
gene id: 146922:HEP81_RS16120
uniprot id: A0A1X4GT74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

146922:HEP81 RS13090
gene id: 146922:HEP81_RS13090
uniprot id: A0A7H1PY28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

146922:HEP81 RS14425
gene id: 146922:HEP81_RS14425
uniprot id: A0A1X4GU58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS14080
gene id: 146922:HEP81_RS14080
uniprot id: A0A7H1PYM2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

146922:HEP81 RS19570
gene id: 146922:HEP81_RS19570
uniprot id: A0A7H1Q1R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

146922:HEP81 RS32290
gene id: 146922:HEP81_RS32290
uniprot id: A0A7H1Q8U4
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS34860
gene id: 146922:HEP81_RS34860
uniprot id: A0A7H1QAB7
names: Similarity
messages: Belongs to the asparagine synthetase family.

146922:HEP81 RS32670
gene id: 146922:HEP81_RS32670
uniprot id: A0A426RZE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS30280
gene id: 146922:HEP81_RS30280
uniprot id: A0A7H1Q7Q4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

146922:HEP81 RS05845
gene id: 146922:HEP81_RS05845
uniprot id: A0A7H1PTX9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

146922:HEP81 RS28285
gene id: 146922:HEP81_RS28285
uniprot id: A0A1X4GMF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS29410
gene id: 146922:HEP81_RS29410
uniprot id: A0A7H1Q782
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

146922:HEP81 RS31385
gene id: 146922:HEP81_RS31385
uniprot id: A0A1X4H3R5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

146922:HEP81 RS17600
gene id: 146922:HEP81_RS17600
uniprot id: A0A3R8RER9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

146922:HEP81 RS19535
gene id: 146922:HEP81_RS19535
uniprot id: A0A1X4GRH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

146922:HEP81 RS26430
gene id: 146922:HEP81_RS26430
uniprot id: A0A7H1Q5J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

146922:HEP81 RS37215
gene id: 146922:HEP81_RS37215
uniprot id: A0A7H1QBN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

146922:HEP81 RS35140
gene id: 146922:HEP81_RS35140
uniprot id: A0A7H1QAH3
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS12640
gene id: 146922:HEP81_RS12640
uniprot id: A0A7H1PXT8
names: Similarity
messages: Belongs to the LOG family.

146922:HEP81 RS34810
gene id: 146922:HEP81_RS34810
uniprot id: A0A7H1QAA7
names: Similarity
messages: Belongs to the universal stress protein A family.

146922:HEP81 RS26035
gene id: 146922:HEP81_RS26035
uniprot id: A0A7H1Q5B7
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS35195
gene id: 146922:HEP81_RS35195
uniprot id: A0A7H1QAI4
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

146922:HEP81 RS24220
gene id: 146922:HEP81_RS24220
uniprot id: A0A1X4GPR0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

146922:HEP81 RS09670
gene id: 146922:HEP81_RS09670
uniprot id: A0A7H1PW51
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS12985
gene id: 146922:HEP81_RS12985
uniprot id: A0A426S2Y6
names: Subcellular Location Annotation
messages: Membrane

146922:HEP81 RS00210
gene id: 146922:HEP81_RS00210
uniprot id: A0A7H1PQP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

146922:HEP81 RS24315
gene id: 146922:HEP81_RS24315
uniprot id: A0A7H1Q4D2
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

146922:HEP81 RS34955
gene id: 146922:HEP81_RS34955
uniprot id: A0A426SCA5
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

146922:HEP81 RS06155
gene id: 146922:HEP81_RS06155
uniprot id: A0A7H1PU41
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

146922:HEP81 RS39380
gene id: 146922:HEP81_RS39380
uniprot id: A0A7H1QCV6
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.