1458426:SMCB RS02200
gene id: 1458426:SMCB_RS02200
uniprot id: A0A060NSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1458426:SMCB RS01285
gene id: 1458426:SMCB_RS01285
uniprot id: A0A060NL57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1458426:SMCB RS06815
gene id: 1458426:SMCB_RS06815
uniprot id: A0A060NXH2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1458426:SMCB RS00170
gene id: 1458426:SMCB_RS00170
uniprot id: A0A060NRV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1458426:SMCB RS06460
gene id: 1458426:SMCB_RS06460
uniprot id: A0A060NP32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1458426:SMCB RS10305
gene id: 1458426:SMCB_RS10305
uniprot id: A0A060NXP2
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS09485
gene id: 1458426:SMCB_RS09485
uniprot id: A0A060NX54
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1458426:SMCB RS09065
gene id: 1458426:SMCB_RS09065
uniprot id: A0A060NWX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraY family.
messages: Cytoplasm

1458426:SMCB RS04330
gene id: 1458426:SMCB_RS04330
uniprot id: A0A060NP05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1458426:SMCB RS04440
gene id: 1458426:SMCB_RS04440
uniprot id: A0A060NKU1
names: Similarity
messages: Belongs to the LOG family.

1458426:SMCB RS00905
gene id: 1458426:SMCB_RS00905
uniprot id: A0A060NU52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1458426:SMCB RS02015
gene id: 1458426:SMCB_RS02015
uniprot id: A0A060NSW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1458426:SMCB RS07775
gene id: 1458426:SMCB_RS07775
uniprot id: A0A060NW78
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS02825
gene id: 1458426:SMCB_RS02825
uniprot id: A0A060NTE5
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1458426:SMCB RS00240
gene id: 1458426:SMCB_RS00240
uniprot id: A0A060NKN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1458426:SMCB RS10510
gene id: 1458426:SMCB_RS10510
uniprot id: A0A060NSP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1458426:SMCB RS00380
gene id: 1458426:SMCB_RS00380
uniprot id: A0A060NLP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1458426:SMCB RS05480
gene id: 1458426:SMCB_RS05480
uniprot id: A0A060NUZ5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1458426:SMCB RS04525
gene id: 1458426:SMCB_RS04525
uniprot id: A0A060NMW9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1458426:SMCB RS04370
gene id: 1458426:SMCB_RS04370
uniprot id: A0A060NMU2
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.

1458426:SMCB RS05850
gene id: 1458426:SMCB_RS05850
uniprot id: A0A060NLK0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1458426:SMCB RS04060
gene id: 1458426:SMCB_RS04060
uniprot id: A0A060NNV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS06190
gene id: 1458426:SMCB_RS06190
uniprot id: A0A060NVA4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1458426:SMCB RS02605
gene id: 1458426:SMCB_RS02605
uniprot id: A0A060NV19
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1458426:SMCB RS06080
gene id: 1458426:SMCB_RS06080
uniprot id: A0A060NLN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS09745
gene id: 1458426:SMCB_RS09745
uniprot id: A0A060NXB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1458426:SMCB RS10555
gene id: 1458426:SMCB_RS10555
uniprot id: A0A060NZS0
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS00670
gene id: 1458426:SMCB_RS00670
uniprot id: A0A060NS81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1458426:SMCB RS02205
gene id: 1458426:SMCB_RS02205
uniprot id: A0A060NUT7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1458426:SMCB RS06520
gene id: 1458426:SMCB_RS06520
uniprot id: A0A060NVF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1458426:SMCB RS10860
gene id: 1458426:SMCB_RS10860
uniprot id: A0A060NSU9
names: Similarity
messages: Belongs to the sigma-54 factor family.

1458426:SMCB RS00955
gene id: 1458426:SMCB_RS00955
uniprot id: A0A060NU57
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1458426:SMCB RS08645
gene id: 1458426:SMCB_RS08645
uniprot id: A0A060NYK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1458426:SMCB RS05185
gene id: 1458426:SMCB_RS05185
uniprot id: A0A060NUQ9
names: Similarity
messages: Belongs to the GST superfamily.

1458426:SMCB RS07590
gene id: 1458426:SMCB_RS07590
uniprot id: A0A060NPQ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1458426:SMCB RS08700
gene id: 1458426:SMCB_RS08700
uniprot id: A0A060NRJ1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1458426:SMCB RS10610
gene id: 1458426:SMCB_RS10610
uniprot id: A0A060NSR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1458426:SMCB RS05760
gene id: 1458426:SMCB_RS05760
uniprot id: A0A060NWY5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1458426:SMCB RS08790
gene id: 1458426:SMCB_RS08790
uniprot id: A0A060NYN3
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS10450
gene id: 1458426:SMCB_RS10450
uniprot id: A0A060NXV5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1458426:SMCB RS05800
gene id: 1458426:SMCB_RS05800
uniprot id: A0A060NNS4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1458426:SMCB RS01205
gene id: 1458426:SMCB_RS01205
uniprot id: A0A060NJI9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1458426:SMCB RS06615
gene id: 1458426:SMCB_RS06615
uniprot id: A0A060NVH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1458426:SMCB RS08635
gene id: 1458426:SMCB_RS08635
uniprot id: A0A060NQD4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1458426:SMCB RS06040
gene id: 1458426:SMCB_RS06040
uniprot id: A0A060NV80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1458426:SMCB RS11910
gene id: 1458426:SMCB_RS11910
uniprot id: A0A060P0E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1458426:SMCB RS10095
gene id: 1458426:SMCB_RS10095
uniprot id: A0A060NXJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1458426:SMCB RS09870
gene id: 1458426:SMCB_RS09870
uniprot id: A0A060NXE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1458426:SMCB RS02270
gene id: 1458426:SMCB_RS02270
uniprot id: A0A060NT14
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458426:SMCB RS10580
gene id: 1458426:SMCB_RS10580
uniprot id: A0A060NZS4
names: PTM
messages: Binds 1 heme group per subunit.

1458426:SMCB RS00395
gene id: 1458426:SMCB_RS00395
uniprot id: A0A060NS06
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1458426:SMCB RS05750
gene id: 1458426:SMCB_RS05750
uniprot id: A0A060NNR7
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

1458426:SMCB RS02435
gene id: 1458426:SMCB_RS02435
uniprot id: A0A060NMU7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1458426:SMCB RS01510
gene id: 1458426:SMCB_RS01510
uniprot id: A0A060NL93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS11735
gene id: 1458426:SMCB_RS11735
uniprot id: A0A060NS26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1458426:SMCB RS08850
gene id: 1458426:SMCB_RS08850
uniprot id: A0A060NN74
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458426:SMCB RS01865
gene id: 1458426:SMCB_RS01865
uniprot id: A0A060NST2
names: Similarity
messages: Belongs to the MotB family.

1458426:SMCB RS01890
gene id: 1458426:SMCB_RS01890
uniprot id: A0A060NST7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1458426:SMCB RS00065
gene id: 1458426:SMCB_RS00065
uniprot id: A0A060NKK3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1458426:SMCB RS07240
gene id: 1458426:SMCB_RS07240
uniprot id: A0A060NPH6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1458426:SMCB RS03840
gene id: 1458426:SMCB_RS03840
uniprot id: A0A060NNR1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1458426:SMCB RS11660
gene id: 1458426:SMCB_RS11660
uniprot id: A0A060NS14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1458426:SMCB RS06935
gene id: 1458426:SMCB_RS06935
uniprot id: A0A060NVN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1458426:SMCB RS10495
gene id: 1458426:SMCB_RS10495
uniprot id: A0A060NRI4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1458426:SMCB RS03790
gene id: 1458426:SMCB_RS03790
uniprot id: A0A060NVQ9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458426:SMCB RS09040
gene id: 1458426:SMCB_RS09040
uniprot id: A0A060NWW8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1458426:SMCB RS07810
gene id: 1458426:SMCB_RS07810
uniprot id: A0A060NR08
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

1458426:SMCB RS10445
gene id: 1458426:SMCB_RS10445
uniprot id: A0A060NRH6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1458426:SMCB RS04390
gene id: 1458426:SMCB_RS04390
uniprot id: A0A060NKT4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1458426:SMCB RS08510
gene id: 1458426:SMCB_RS08510
uniprot id: A0A060NQB3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS00115
gene id: 1458426:SMCB_RS00115
uniprot id: A0A060NKL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1458426:SMCB RS11520
gene id: 1458426:SMCB_RS11520
uniprot id: A0A060P076
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1458426:SMCB RS10795
gene id: 1458426:SMCB_RS10795
uniprot id: A0A060NRM6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1458426:SMCB RS01940
gene id: 1458426:SMCB_RS01940
uniprot id: A0A060NSU5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1458426:SMCB RS07085
gene id: 1458426:SMCB_RS07085
uniprot id: A0A060NXM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1458426:SMCB RS03650
gene id: 1458426:SMCB_RS03650
uniprot id: A0A060NKH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1458426:SMCB RS07010
gene id: 1458426:SMCB_RS07010
uniprot id: A0A060NXL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1458426:SMCB RS11890
gene id: 1458426:SMCB_RS11890
uniprot id: A0A060NTC9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1458426:SMCB RS05630
gene id: 1458426:SMCB_RS05630
uniprot id: A0A060NNP8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS05070
gene id: 1458426:SMCB_RS05070
uniprot id: A0A060NWG6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS01135
gene id: 1458426:SMCB_RS01135
uniprot id: A0A060NSF2
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1458426:SMCB RS01995
gene id: 1458426:SMCB_RS01995
uniprot id: A0A060NUP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1458426:SMCB RS09500
gene id: 1458426:SMCB_RS09500
uniprot id: A0A060NNJ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1458426:SMCB RS09110
gene id: 1458426:SMCB_RS09110
uniprot id: A0A060NWY4
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1458426:SMCB RS04030
gene id: 1458426:SMCB_RS04030
uniprot id: A0A060NVV6
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS06415
gene id: 1458426:SMCB_RS06415
uniprot id: A0A060NVD5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1458426:SMCB RS09600
gene id: 1458426:SMCB_RS09600
uniprot id: A0A060NNM1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1458426:SMCB RS10985
gene id: 1458426:SMCB_RS10985
uniprot id: A0A060NNF9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1458426:SMCB RS05675
gene id: 1458426:SMCB_RS05675
uniprot id: A0A060NLH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1458426:SMCB RS09255
gene id: 1458426:SMCB_RS09255
uniprot id: A0A060NQN5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1458426:SMCB RS10240
gene id: 1458426:SMCB_RS10240
uniprot id: A0A060NXM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1458426:SMCB RS06465
gene id: 1458426:SMCB_RS06465
uniprot id: A0A060NVE4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1458426:SMCB RS04445
gene id: 1458426:SMCB_RS04445
uniprot id: A0A060NMV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1458426:SMCB RS03755
gene id: 1458426:SMCB_RS03755
uniprot id: A0A060NMJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS00090
gene id: 1458426:SMCB_RS00090
uniprot id: A0A060NKK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1458426:SMCB RS11295
gene id: 1458426:SMCB_RS11295
uniprot id: A0A060NRV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS08400
gene id: 1458426:SMCB_RS08400
uniprot id: A0A060NYG6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1458426:SMCB RS04430
gene id: 1458426:SMCB_RS04430
uniprot id: A0A060NW38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS05580
gene id: 1458426:SMCB_RS05580
uniprot id: A0A060NNP0
names: Similarity
messages: Belongs to the PstS family.

1458426:SMCB RS05815
gene id: 1458426:SMCB_RS05815
uniprot id: A0A060NWZ1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1458426:SMCB RS04755
gene id: 1458426:SMCB_RS04755
uniprot id: A0A060NUF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458426:SMCB RS10340
gene id: 1458426:SMCB_RS10340
uniprot id: A0A060NSI1
names: Similarity
messages: Belongs to the MotB family.

1458426:SMCB RS00875
gene id: 1458426:SMCB_RS00875
uniprot id: A0A060NSB5
names: Similarity
messages: Belongs to the glutamine synthetase family.

1458426:SMCB RS01040
gene id: 1458426:SMCB_RS01040
uniprot id: A0A060NM41
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1458426:SMCB RS09150
gene id: 1458426:SMCB_RS09150
uniprot id: A0A060NNC6
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1458426:SMCB RS00580
gene id: 1458426:SMCB_RS00580
uniprot id: A0A060NJD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1458426:SMCB RS02500
gene id: 1458426:SMCB_RS02500
uniprot id: A0A060NT66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1458426:SMCB RS01845
gene id: 1458426:SMCB_RS01845
uniprot id: A0A060NUL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1458426:SMCB RS02890
gene id: 1458426:SMCB_RS02890
uniprot id: A0A060NK72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1458426:SMCB RS05700
gene id: 1458426:SMCB_RS05700
uniprot id: A0A060NLH8
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS01965
gene id: 1458426:SMCB_RS01965
uniprot id: A0A060NSV0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1458426:SMCB RS01410
gene id: 1458426:SMCB_RS01410
uniprot id: A0A060NSJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1458426:SMCB RS01785
gene id: 1458426:SMCB_RS01785
uniprot id: A0A060NLD3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1458426:SMCB RS01375
gene id: 1458426:SMCB_RS01375
uniprot id: A0A060NJK3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1458426:SMCB RS06105
gene id: 1458426:SMCB_RS06105
uniprot id: A0A060NLN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1458426:SMCB RS06560
gene id: 1458426:SMCB_RS06560
uniprot id: A0A060NP50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1458426:SMCB RS08750
gene id: 1458426:SMCB_RS08750
uniprot id: A0A060NN60
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458426:SMCB RS05260
gene id: 1458426:SMCB_RS05260
uniprot id: A0A060NUS5
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1458426:SMCB RS08335
gene id: 1458426:SMCB_RS08335
uniprot id: A0A060NMZ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1458426:SMCB RS06855
gene id: 1458426:SMCB_RS06855
uniprot id: A0A060NP96
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458426:SMCB RS05985
gene id: 1458426:SMCB_RS05985
uniprot id: A0A060NNV4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1458426:SMCB RS10135
gene id: 1458426:SMCB_RS10135
uniprot id: A0A060NNZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1458426:SMCB RS07545
gene id: 1458426:SMCB_RS07545
uniprot id: A0A060NW23
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1458426:SMCB RS00585
gene id: 1458426:SMCB_RS00585
uniprot id: A0A060NKX2
names: Similarity
messages: Belongs to the UPF0102 family.

1458426:SMCB RS11120
gene id: 1458426:SMCB_RS11120
uniprot id: A0A060NRS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1458426:SMCB RS11880
gene id: 1458426:SMCB_RS11880
uniprot id: A0A060NYH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1458426:SMCB RS10220
gene id: 1458426:SMCB_RS10220
uniprot id: A0A060NZH5
names: Similarity
messages: Belongs to the TrpC family.

1458426:SMCB RS03120
gene id: 1458426:SMCB_RS03120
uniprot id: A0A060NVG5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1458426:SMCB RS09855
gene id: 1458426:SMCB_RS09855
uniprot id: A0A060NS64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1458426:SMCB RS02585
gene id: 1458426:SMCB_RS02585
uniprot id: A0A060NV13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1458426:SMCB RS08810
gene id: 1458426:SMCB_RS08810
uniprot id: A0A060NWT0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1458426:SMCB RS10665
gene id: 1458426:SMCB_RS10665
uniprot id: A0A060NPA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1458426:SMCB RS02620
gene id: 1458426:SMCB_RS02620
uniprot id: A0A060NLT6
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS02045
gene id: 1458426:SMCB_RS02045
uniprot id: A0A060NUQ8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1458426:SMCB RS06990
gene id: 1458426:SMCB_RS06990
uniprot id: A0A060NQI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1458426:SMCB RS02855
gene id: 1458426:SMCB_RS02855
uniprot id: A0A060NV88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1458426:SMCB RS08415
gene id: 1458426:SMCB_RS08415
uniprot id: A0A060NQ99
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1458426:SMCB RS01525
gene id: 1458426:SMCB_RS01525
uniprot id: A0A060NMC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS13090
gene id: 1458426:SMCB_RS13090
uniprot id: A0A060NVK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1458426:SMCB RS07655
gene id: 1458426:SMCB_RS07655
uniprot id: A0A060NY00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1458426:SMCB RS00250
gene id: 1458426:SMCB_RS00250
uniprot id: A0A060NTQ8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1458426:SMCB RS10110
gene id: 1458426:SMCB_RS10110
uniprot id: A0A060NNZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1458426:SMCB RS01625
gene id: 1458426:SMCB_RS01625
uniprot id: A0A060NME6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1458426:SMCB RS11430
gene id: 1458426:SMCB_RS11430
uniprot id: A0A060NT49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1458426:SMCB RS06625
gene id: 1458426:SMCB_RS06625
uniprot id: A0A060NQB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS06010
gene id: 1458426:SMCB_RS06010
uniprot id: A0A060NNV9
names: Cofactor
messages: Can also use Mn(2+) ion.

1458426:SMCB RS10595
gene id: 1458426:SMCB_RS10595
uniprot id: A0A060NRK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1458426:SMCB RS02790
gene id: 1458426:SMCB_RS02790
uniprot id: A0A060NK56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS00895
gene id: 1458426:SMCB_RS00895
uniprot id: A0A060NL11
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1458426:SMCB RS01605
gene id: 1458426:SMCB_RS01605
uniprot id: A0A060NJM6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1458426:SMCB RS03880
gene id: 1458426:SMCB_RS03880
uniprot id: A0A060NTY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1458426:SMCB RS02485
gene id: 1458426:SMCB_RS02485
uniprot id: A0A060NMV9
names: Similarity
messages: Belongs to the RecJ family.

1458426:SMCB RS08110
gene id: 1458426:SMCB_RS08110
uniprot id: A0A060NWG9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1458426:SMCB RS06330
gene id: 1458426:SMCB_RS06330
uniprot id: A0A060NLS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1458426:SMCB RS10780
gene id: 1458426:SMCB_RS10780
uniprot id: A0A060NZV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1458426:SMCB RS02530
gene id: 1458426:SMCB_RS02530
uniprot id: A0A060NV00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1458426:SMCB RS08375
gene id: 1458426:SMCB_RS08375
uniprot id: A0A060NYG3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1458426:SMCB RS10035
gene id: 1458426:SMCB_RS10035
uniprot id: A0A060NNX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1458426:SMCB RS07630
gene id: 1458426:SMCB_RS07630
uniprot id: A0A060NXZ2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1458426:SMCB RS03670
gene id: 1458426:SMCB_RS03670
uniprot id: A0A060NNM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1458426:SMCB RS05655
gene id: 1458426:SMCB_RS05655
uniprot id: A0A060NNQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1458426:SMCB RS01770
gene id: 1458426:SMCB_RS01770
uniprot id: A0A060NUK4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1458426:SMCB RS08595
gene id: 1458426:SMCB_RS08595
uniprot id: A0A060NYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1458426:SMCB RS02190
gene id: 1458426:SMCB_RS02190
uniprot id: A0A060NJV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1458426:SMCB RS02515
gene id: 1458426:SMCB_RS02515
uniprot id: A0A060NK08
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1458426:SMCB RS02600
gene id: 1458426:SMCB_RS02600
uniprot id: A0A060NT90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1458426:SMCB RS00915
gene id: 1458426:SMCB_RS00915
uniprot id: A0A060NJG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1458426:SMCB RS07255
gene id: 1458426:SMCB_RS07255
uniprot id: A0A060NMB2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1458426:SMCB RS10930
gene id: 1458426:SMCB_RS10930
uniprot id: A0A060NZX3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1458426:SMCB RS05725
gene id: 1458426:SMCB_RS05725
uniprot id: A0A060NNR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1458426:SMCB RS06550
gene id: 1458426:SMCB_RS06550
uniprot id: A0A060NQA5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1458426:SMCB RS02925
gene id: 1458426:SMCB_RS02925
uniprot id: A0A060NTG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1458426:SMCB RS00560
gene id: 1458426:SMCB_RS00560
uniprot id: A0A060NKW9
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS01915
gene id: 1458426:SMCB_RS01915
uniprot id: A0A060NSU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1458426:SMCB RS02450
gene id: 1458426:SMCB_RS02450
uniprot id: A0A060NT56
names: Similarity
messages: Belongs to the UPF0246 family.

1458426:SMCB RS05995
gene id: 1458426:SMCB_RS05995
uniprot id: A0A060NX16
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1458426:SMCB RS00950
gene id: 1458426:SMCB_RS00950
uniprot id: A0A060NSC6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1458426:SMCB RS04090
gene id: 1458426:SMCB_RS04090
uniprot id: A0A060NKN6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1458426:SMCB RS05470
gene id: 1458426:SMCB_RS05470
uniprot id: A0A060NLF1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1458426:SMCB RS06510
gene id: 1458426:SMCB_RS06510
uniprot id: A0A060NLV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1458426:SMCB RS03635
gene id: 1458426:SMCB_RS03635
uniprot id: A0A060NTU9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1458426:SMCB RS12210
gene id: 1458426:SMCB_RS12210
uniprot id: A0A060NMY1
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1458426:SMCB RS04980
gene id: 1458426:SMCB_RS04980
uniprot id: A0A060NL36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

1458426:SMCB RS01025
gene id: 1458426:SMCB_RS01025
uniprot id: A0A060NL25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1458426:SMCB RS07555
gene id: 1458426:SMCB_RS07555
uniprot id: A0A060NQU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1458426:SMCB RS09810
gene id: 1458426:SMCB_RS09810
uniprot id: A0A060NNR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS01230
gene id: 1458426:SMCB_RS01230
uniprot id: A0A060NJJ1
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1458426:SMCB RS01055
gene id: 1458426:SMCB_RS01055
uniprot id: A0A060NSE0
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1458426:SMCB RS05265
gene id: 1458426:SMCB_RS05265
uniprot id: A0A060NWM0
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1458426:SMCB RS06070
gene id: 1458426:SMCB_RS06070
uniprot id: A0A060NX28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1458426:SMCB RS09435
gene id: 1458426:SMCB_RS09435
uniprot id: A0A060NX45
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1458426:SMCB RS07465
gene id: 1458426:SMCB_RS07465
uniprot id: A0A060NPM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1458426:SMCB RS09465
gene id: 1458426:SMCB_RS09465
uniprot id: A0A060NZ16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1458426:SMCB RS02090
gene id: 1458426:SMCB_RS02090
uniprot id: A0A060NUR7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1458426:SMCB RS11085
gene id: 1458426:SMCB_RS11085
uniprot id: A0A060NSY4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1458426:SMCB RS08275
gene id: 1458426:SMCB_RS08275
uniprot id: A0A060NYE7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS03045
gene id: 1458426:SMCB_RS03045
uniprot id: A0A060NK99
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1458426:SMCB RS05180
gene id: 1458426:SMCB_RS05180
uniprot id: A0A060NNB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1458426:SMCB RS01420
gene id: 1458426:SMCB_RS01420
uniprot id: A0A060NMA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1458426:SMCB RS05240
gene id: 1458426:SMCB_RS05240
uniprot id: A0A060NWL4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1458426:SMCB RS09720
gene id: 1458426:SMCB_RS09720
uniprot id: A0A060NXA8
names: Similarity
messages: Belongs to the universal stress protein A family.

1458426:SMCB RS10635
gene id: 1458426:SMCB_RS10635
uniprot id: A0A060NSR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1458426:SMCB RS08570
gene id: 1458426:SMCB_RS08570
uniprot id: A0A060NYJ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1458426:SMCB RS10645
gene id: 1458426:SMCB_RS10645
uniprot id: A0A060NRK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1458426:SMCB RS04630
gene id: 1458426:SMCB_RS04630
uniprot id: A0A060NUC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1458426:SMCB RS01530
gene id: 1458426:SMCB_RS01530
uniprot id: A0A060NJL8
names: Similarity
messages: Belongs to the P(II) protein family.

1458426:SMCB RS07585
gene id: 1458426:SMCB_RS07585
uniprot id: A0A060NMJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1458426:SMCB RS09985
gene id: 1458426:SMCB_RS09985
uniprot id: A0A060NNW4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1458426:SMCB RS06585
gene id: 1458426:SMCB_RS06585
uniprot id: A0A060NP53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1458426:SMCB RS07390
gene id: 1458426:SMCB_RS07390
uniprot id: A0A060NVY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1458426:SMCB RS05440
gene id: 1458426:SMCB_RS05440
uniprot id: A0A060NWT2
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1458426:SMCB RS03640
gene id: 1458426:SMCB_RS03640
uniprot id: A0A060NVN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1458426:SMCB RS00160
gene id: 1458426:SMCB_RS00160
uniprot id: A0A060NJ62
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS00145
gene id: 1458426:SMCB_RS00145
uniprot id: A0A060NRU8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458426:SMCB RS09420
gene id: 1458426:SMCB_RS09420
uniprot id: A0A060NRY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1458426:SMCB RS10400
gene id: 1458426:SMCB_RS10400
uniprot id: A0A060NXR6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1458426:SMCB RS01860
gene id: 1458426:SMCB_RS01860
uniprot id: A0A060NLE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1458426:SMCB RS02180
gene id: 1458426:SMCB_RS02180
uniprot id: A0A060NUT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1458426:SMCB RS04895
gene id: 1458426:SMCB_RS04895
uniprot id: A0A060NWC3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1458426:SMCB RS04850
gene id: 1458426:SMCB_RS04850
uniprot id: A0A060NP97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1458426:SMCB RS02000
gene id: 1458426:SMCB_RS02000
uniprot id: A0A060NMM1
names: Similarity
messages: Belongs to the peptidase S11 family.

1458426:SMCB RS06505
gene id: 1458426:SMCB_RS06505
uniprot id: A0A060NQ95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1458426:SMCB RS02145
gene id: 1458426:SMCB_RS02145
uniprot id: A0A060NSY6
names: Similarity
messages: Belongs to the HesB/IscA family.

1458426:SMCB RS10560
gene id: 1458426:SMCB_RS10560
uniprot id: A0A060NSQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1458426:SMCB RS01455
gene id: 1458426:SMCB_RS01455
uniprot id: A0A060NL84
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1458426:SMCB RS01480
gene id: 1458426:SMCB_RS01480
uniprot id: A0A060NL88
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS08685
gene id: 1458426:SMCB_RS08685
uniprot id: A0A060NQE4
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1458426:SMCB RS10630
gene id: 1458426:SMCB_RS10630
uniprot id: A0A060NZT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1458426:SMCB RS05290
gene id: 1458426:SMCB_RS05290
uniprot id: A0A060NWM6
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1458426:SMCB RS08155
gene id: 1458426:SMCB_RS08155
uniprot id: A0A060NQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1458426:SMCB RS09265
gene id: 1458426:SMCB_RS09265
uniprot id: A0A060NYX7
names: Similarity
messages: Belongs to the BolA/IbaG family.

1458426:SMCB RS04420
gene id: 1458426:SMCB_RS04420
uniprot id: A0A060NMV0
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS00650
gene id: 1458426:SMCB_RS00650
uniprot id: A0A060NU17
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1458426:SMCB RS05935
gene id: 1458426:SMCB_RS05935
uniprot id: A0A060NV66
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS04045
gene id: 1458426:SMCB_RS04045
uniprot id: A0A060NMP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1458426:SMCB RS00120
gene id: 1458426:SMCB_RS00120
uniprot id: A0A060NRU2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1458426:SMCB RS02185
gene id: 1458426:SMCB_RS02185
uniprot id: A0A060NMQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1458426:SMCB RS10100
gene id: 1458426:SMCB_RS10100
uniprot id: A0A060NZF0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1458426:SMCB RS05030
gene id: 1458426:SMCB_RS05030
uniprot id: A0A060NL43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1458426:SMCB RS09740
gene id: 1458426:SMCB_RS09740
uniprot id: A0A060NQY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1458426:SMCB RS11290
gene id: 1458426:SMCB_RS11290
uniprot id: A0A060NPJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS07360
gene id: 1458426:SMCB_RS07360
uniprot id: A0A060NPK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1458426:SMCB RS05970
gene id: 1458426:SMCB_RS05970
uniprot id: A0A060NX11
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1458426:SMCB RS11715
gene id: 1458426:SMCB_RS11715
uniprot id: A0A060NYF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1458426:SMCB RS04455
gene id: 1458426:SMCB_RS04455
uniprot id: A0A060NW43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1458426:SMCB RS00550
gene id: 1458426:SMCB_RS00550
uniprot id: A0A060NLW6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1458426:SMCB RS06310
gene id: 1458426:SMCB_RS06310
uniprot id: A0A060NP06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS05485
gene id: 1458426:SMCB_RS05485
uniprot id: A0A060NWU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1458426:SMCB RS04625
gene id: 1458426:SMCB_RS04625
uniprot id: A0A060NMZ2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1458426:SMCB RS01695
gene id: 1458426:SMCB_RS01695
uniprot id: A0A060NUI8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1458426:SMCB RS05860
gene id: 1458426:SMCB_RS05860
uniprot id: A0A060NV54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS11185
gene id: 1458426:SMCB_RS11185
uniprot id: A0A060NT03
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1458426:SMCB RS11005
gene id: 1458426:SMCB_RS11005
uniprot id: A0A060NY38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1458426:SMCB RS05830
gene id: 1458426:SMCB_RS05830
uniprot id: A0A060NNS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1458426:SMCB RS01295
gene id: 1458426:SMCB_RS01295
uniprot id: A0A060NUA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS01490
gene id: 1458426:SMCB_RS01490
uniprot id: A0A060NUE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1458426:SMCB RS04650
gene id: 1458426:SMCB_RS04650
uniprot id: A0A060NUD2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1458426:SMCB RS07460
gene id: 1458426:SMCB_RS07460
uniprot id: A0A060NMG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1458426:SMCB RS05055
gene id: 1458426:SMCB_RS05055
uniprot id: A0A060NL48
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458426:SMCB RS01930
gene id: 1458426:SMCB_RS01930
uniprot id: A0A060NJR2
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1458426:SMCB RS01390
gene id: 1458426:SMCB_RS01390
uniprot id: A0A060NUC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1458426:SMCB RS07220
gene id: 1458426:SMCB_RS07220
uniprot id: A0A060NVU2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1458426:SMCB RS09175
gene id: 1458426:SMCB_RS09175
uniprot id: A0A060NND2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1458426:SMCB RS00175
gene id: 1458426:SMCB_RS00175
uniprot id: A0A060NTN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1458426:SMCB RS04460
gene id: 1458426:SMCB_RS04460
uniprot id: A0A060NP29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1458426:SMCB RS07690
gene id: 1458426:SMCB_RS07690
uniprot id: A0A060NML9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1458426:SMCB RS11345
gene id: 1458426:SMCB_RS11345
uniprot id: A0A060NRW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1458426:SMCB RS06365
gene id: 1458426:SMCB_RS06365
uniprot id: A0A060NVC9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1458426:SMCB RS09195
gene id: 1458426:SMCB_RS09195
uniprot id: A0A060NRU0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1458426:SMCB RS07745
gene id: 1458426:SMCB_RS07745
uniprot id: A0A060NPT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1458426:SMCB RS08295
gene id: 1458426:SMCB_RS08295
uniprot id: A0A060NWJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1458426:SMCB RS00825
gene id: 1458426:SMCB_RS00825
uniprot id: A0A060NSA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1458426:SMCB RS07770
gene id: 1458426:SMCB_RS07770
uniprot id: A0A060NPU5
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS04325
gene id: 1458426:SMCB_RS04325
uniprot id: A0A060NW18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1458426:SMCB RS09610
gene id: 1458426:SMCB_RS09610
uniprot id: A0A060NX83
names: Similarity
messages: Belongs to the universal stress protein A family.

1458426:SMCB RS10915
gene id: 1458426:SMCB_RS10915
uniprot id: A0A060NPD7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1458426:SMCB RS08285
gene id: 1458426:SMCB_RS08285
uniprot id: A0A060NMZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1458426:SMCB RS08420
gene id: 1458426:SMCB_RS08420
uniprot id: A0A060NWL9
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1458426:SMCB RS11070
gene id: 1458426:SMCB_RS11070
uniprot id: A0A060NRR9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1458426:SMCB RS00850
gene id: 1458426:SMCB_RS00850
uniprot id: A0A060NSB2
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS05010
gene id: 1458426:SMCB_RS05010
uniprot id: A0A060NN72
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1458426:SMCB RS04265
gene id: 1458426:SMCB_RS04265
uniprot id: A0A060NMT0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1458426:SMCB RS01155
gene id: 1458426:SMCB_RS01155
uniprot id: A0A060NL41
names: Cofactor
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1458426:SMCB RS04205
gene id: 1458426:SMCB_RS04205
uniprot id: A0A060NNY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS06895
gene id: 1458426:SMCB_RS06895
uniprot id: A0A060NQH0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1458426:SMCB RS05490
gene id: 1458426:SMCB_RS05490
uniprot id: A0A060NPT2
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1458426:SMCB RS05745
gene id: 1458426:SMCB_RS05745
uniprot id: A0A060NLI3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1458426:SMCB RS01765
gene id: 1458426:SMCB_RS01765
uniprot id: A0A060NSR1
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1458426:SMCB RS10030
gene id: 1458426:SMCB_RS10030
uniprot id: A0A060NSB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1458426:SMCB RS10845
gene id: 1458426:SMCB_RS10845
uniprot id: A0A060NRN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1458426:SMCB RS01440
gene id: 1458426:SMCB_RS01440
uniprot id: A0A060NUD6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1458426:SMCB RS10685
gene id: 1458426:SMCB_RS10685
uniprot id: A0A060NSS5
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1458426:SMCB RS07445
gene id: 1458426:SMCB_RS07445
uniprot id: A0A060NXU8
names: Similarity
messages: Belongs to the P(II) protein family.

1458426:SMCB RS08955
gene id: 1458426:SMCB_RS08955
uniprot id: A0A060NN92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1458426:SMCB RS10895
gene id: 1458426:SMCB_RS10895
uniprot id: A0A060NRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1458426:SMCB RS06635
gene id: 1458426:SMCB_RS06635
uniprot id: A0A060NVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1458426:SMCB RS02405
gene id: 1458426:SMCB_RS02405
uniprot id: A0A060NMU1
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1458426:SMCB RS10625
gene id: 1458426:SMCB_RS10625
uniprot id: A0A060NXY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1458426:SMCB RS03995
gene id: 1458426:SMCB_RS03995
uniprot id: A0A060NMN3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458426:SMCB RS01225
gene id: 1458426:SMCB_RS01225
uniprot id: A0A060NM69
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1458426:SMCB RS00325
gene id: 1458426:SMCB_RS00325
uniprot id: A0A060NRZ0
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1458426:SMCB RS10620
gene id: 1458426:SMCB_RS10620
uniprot id: A0A060NRK6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1458426:SMCB RS00185
gene id: 1458426:SMCB_RS00185
uniprot id: A0A060NJ67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1458426:SMCB RS08300
gene id: 1458426:SMCB_RS08300
uniprot id: A0A060NYF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1458426:SMCB RS07620
gene id: 1458426:SMCB_RS07620
uniprot id: A0A060NPQ8
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

1458426:SMCB RS04470
gene id: 1458426:SMCB_RS04470
uniprot id: A0A060NMW0
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1458426:SMCB RS08535
gene id: 1458426:SMCB_RS08535
uniprot id: A0A060NQB8
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1458426:SMCB RS01935
gene id: 1458426:SMCB_RS01935
uniprot id: A0A060NLF0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1458426:SMCB RS07560
gene id: 1458426:SMCB_RS07560
uniprot id: A0A060NMI9
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1458426:SMCB RS07245
gene id: 1458426:SMCB_RS07245
uniprot id: A0A060NVU9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458426:SMCB RS00150
gene id: 1458426:SMCB_RS00150
uniprot id: A0A060NTN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1458426:SMCB RS04555
gene id: 1458426:SMCB_RS04555
uniprot id: A0A060NUB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS04815
gene id: 1458426:SMCB_RS04815
uniprot id: A0A060NWA8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1458426:SMCB RS06435
gene id: 1458426:SMCB_RS06435
uniprot id: A0A060NP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1458426:SMCB RS02480
gene id: 1458426:SMCB_RS02480
uniprot id: A0A060NUY6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1458426:SMCB RS00215
gene id: 1458426:SMCB_RS00215
uniprot id: A0A060NKM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1458426:SMCB RS11000
gene id: 1458426:SMCB_RS11000
uniprot id: A0A060NRQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1458426:SMCB RS05060
gene id: 1458426:SMCB_RS05060
uniprot id: A0A060NN85
names: Similarity
messages: Belongs to the asparaginase 1 family.

1458426:SMCB RS03615
gene id: 1458426:SMCB_RS03615
uniprot id: A0A060NVN1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS05275
gene id: 1458426:SMCB_RS05275
uniprot id: A0A060NL97
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS04055
gene id: 1458426:SMCB_RS04055
uniprot id: A0A060NVW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS02340
gene id: 1458426:SMCB_RS02340
uniprot id: A0A060NJX9
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1458426:SMCB RS07115
gene id: 1458426:SMCB_RS07115
uniprot id: A0A060NM81
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS00840
gene id: 1458426:SMCB_RS00840
uniprot id: A0A060NJF7
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1458426:SMCB RS09580
gene id: 1458426:SMCB_RS09580
uniprot id: A0A060NQV2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1458426:SMCB RS00385
gene id: 1458426:SMCB_RS00385
uniprot id: A0A060NJ96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1458426:SMCB RS11505
gene id: 1458426:SMCB_RS11505
uniprot id: A0A060NPN3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1458426:SMCB RS09045
gene id: 1458426:SMCB_RS09045
uniprot id: A0A060NYT4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1458426:SMCB RS11635
gene id: 1458426:SMCB_RS11635
uniprot id: A0A060NS11
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1458426:SMCB RS05695
gene id: 1458426:SMCB_RS05695
uniprot id: A0A060NPW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1458426:SMCB RS00085
gene id: 1458426:SMCB_RS00085
uniprot id: A0A060NJ52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1458426:SMCB RS06470
gene id: 1458426:SMCB_RS06470
uniprot id: A0A060NXA0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1458426:SMCB RS11650
gene id: 1458426:SMCB_RS11650
uniprot id: A0A060NT91
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1458426:SMCB RS04605
gene id: 1458426:SMCB_RS04605
uniprot id: A0A060NUC0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1458426:SMCB RS09775
gene id: 1458426:SMCB_RS09775
uniprot id: A0A060NZ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1458426:SMCB RS06525
gene id: 1458426:SMCB_RS06525
uniprot id: A0A060NXA9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS07365
gene id: 1458426:SMCB_RS07365
uniprot id: A0A060NVX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS05375
gene id: 1458426:SMCB_RS05375
uniprot id: A0A060NLB7
names: Similarity
messages: Belongs to the peptidase S66 family.

1458426:SMCB RS06835
gene id: 1458426:SMCB_RS06835
uniprot id: A0A060NVL3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1458426:SMCB RS00230
gene id: 1458426:SMCB_RS00230
uniprot id: A0A060NLL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1458426:SMCB RS08145
gene id: 1458426:SMCB_RS08145
uniprot id: A0A060NRA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1458426:SMCB RS10890
gene id: 1458426:SMCB_RS10890
uniprot id: A0A060NPD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1458426:SMCB RS09270
gene id: 1458426:SMCB_RS09270
uniprot id: A0A060NRV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1458426:SMCB RS08385
gene id: 1458426:SMCB_RS08385
uniprot id: A0A060NN05
names: Similarity
messages: Belongs to the fabD family.

1458426:SMCB RS05575
gene id: 1458426:SMCB_RS05575
uniprot id: A0A060NLG4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1458426:SMCB RS00635
gene id: 1458426:SMCB_RS00635
uniprot id: A0A060NJD8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1458426:SMCB RS04960
gene id: 1458426:SMCB_RS04960
uniprot id: A0A060NN62
names: Similarity
messages: Belongs to the UPF0758 family.

1458426:SMCB RS06665
gene id: 1458426:SMCB_RS06665
uniprot id: A0A060NVI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1458426:SMCB RS10310
gene id: 1458426:SMCB_RS10310
uniprot id: A0A060NZK0
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS07820
gene id: 1458426:SMCB_RS07820
uniprot id: A0A060NPW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1458426:SMCB RS06795
gene id: 1458426:SMCB_RS06795
uniprot id: A0A060NQF1
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS08135
gene id: 1458426:SMCB_RS08135
uniprot id: A0A060NWH2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1458426:SMCB RS00735
gene id: 1458426:SMCB_RS00735
uniprot id: A0A060NU30
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1458426:SMCB RS01670
gene id: 1458426:SMCB_RS01670
uniprot id: A0A060NUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1458426:SMCB RS10490
gene id: 1458426:SMCB_RS10490
uniprot id: A0A060NP88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

1458426:SMCB RS08390
gene id: 1458426:SMCB_RS08390
uniprot id: A0A060NQ94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1458426:SMCB RS00010
gene id: 1458426:SMCB_RS00010
uniprot id: A0A060NLG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1458426:SMCB RS07795
gene id: 1458426:SMCB_RS07795
uniprot id: A0A060NPV3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS10565
gene id: 1458426:SMCB_RS10565
uniprot id: A0A060NP95
names: Subcellular Location Annotation
messages: Cytoplasm

1458426:SMCB RS04380
gene id: 1458426:SMCB_RS04380
uniprot id: A0A060NW27
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1458426:SMCB RS00530
gene id: 1458426:SMCB_RS00530
uniprot id: A0A060NJC9
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1458426:SMCB RS05035
gene id: 1458426:SMCB_RS05035
uniprot id: A0A060NN78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1458426:SMCB RS06735
gene id: 1458426:SMCB_RS06735
uniprot id: A0A060NVJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1458426:SMCB RS10145
gene id: 1458426:SMCB_RS10145
uniprot id: A0A060NXL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1458426:SMCB RS02275
gene id: 1458426:SMCB_RS02275
uniprot id: A0A060NUV1
names: Similarity
messages: Belongs to the pirin family.

1458426:SMCB RS09190
gene id: 1458426:SMCB_RS09190
uniprot id: A0A060NYW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1458426:SMCB RS01340
gene id: 1458426:SMCB_RS01340
uniprot id: A0A060NSI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1458426:SMCB RS11065
gene id: 1458426:SMCB_RS11065
uniprot id: A0A060NPG1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1458426:SMCB RS03085
gene id: 1458426:SMCB_RS03085
uniprot id: A0A060NKA4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1458426:SMCB RS06820
gene id: 1458426:SMCB_RS06820
uniprot id: A0A060NQF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1458426:SMCB RS10040
gene id: 1458426:SMCB_RS10040
uniprot id: A0A060NR48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1458426:SMCB RS05020
gene id: 1458426:SMCB_RS05020
uniprot id: A0A060NWF4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1458426:SMCB RS04875
gene id: 1458426:SMCB_RS04875
uniprot id: A0A060NPA3
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1458426:SMCB RS09800
gene id: 1458426:SMCB_RS09800
uniprot id: A0A060NZ81
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS05100
gene id: 1458426:SMCB_RS05100
uniprot id: A0A060NPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458426:SMCB RS00755
gene id: 1458426:SMCB_RS00755
uniprot id: A0A060NS95
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1458426:SMCB RS05710
gene id: 1458426:SMCB_RS05710
uniprot id: A0A060NWY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1458426:SMCB RS09575
gene id: 1458426:SMCB_RS09575
uniprot id: A0A060NNL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Membrane

1458426:SMCB RS07350
gene id: 1458426:SMCB_RS07350
uniprot id: A0A060NQQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1458426:SMCB RS06355
gene id: 1458426:SMCB_RS06355
uniprot id: A0A060NLS5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458426:SMCB RS11340
gene id: 1458426:SMCB_RS11340
uniprot id: A0A060NPK5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1458426:SMCB RS04670
gene id: 1458426:SMCB_RS04670
uniprot id: A0A060NKX8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1458426:SMCB RS02635
gene id: 1458426:SMCB_RS02635
uniprot id: A0A060NMZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458426:SMCB RS10640
gene id: 1458426:SMCB_RS10640
uniprot id: A0A060NPA4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1458426:SMCB RS05400
gene id: 1458426:SMCB_RS05400
uniprot id: A0A060NLC3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458426:SMCB RS05015
gene id: 1458426:SMCB_RS05015
uniprot id: A0A060NUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1458426:SMCB RS04820
gene id: 1458426:SMCB_RS04820
uniprot id: A0A060NP92
names: Similarity
messages: Belongs to the DEAD box helicase family.

1458426:SMCB RS09380
gene id: 1458426:SMCB_RS09380
uniprot id: A0A060NQQ7
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1458426:SMCB RS11250
gene id: 1458426:SMCB_RS11250
uniprot id: A0A060NY76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1458426:SMCB RS13145
gene id: 1458426:SMCB_RS13145
uniprot id: A0A060NTD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1458426:SMCB RS01220
gene id: 1458426:SMCB_RS01220
uniprot id: A0A060NU97
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1458426:SMCB RS02010
gene id: 1458426:SMCB_RS02010
uniprot id: A0A060NLG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1458426:SMCB RS08170
gene id: 1458426:SMCB_RS08170
uniprot id: A0A060NRA8
names: Similarity
messages: Belongs to the citrate synthase family.

1458426:SMCB RS00195
gene id: 1458426:SMCB_RS00195
uniprot id: A0A060NRW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1458426:SMCB RS09865
gene id: 1458426:SMCB_RS09865
uniprot id: A0A060NR11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1458426:SMCB RS10600
gene id: 1458426:SMCB_RS10600
uniprot id: A0A060NXX9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1458426:SMCB RS02835
gene id: 1458426:SMCB_RS02835
uniprot id: A0A060NN53
names: Function
names: Similarity
messages: Belongs to the ClpA/ClpB family.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1458426:SMCB RS08795
gene id: 1458426:SMCB_RS08795
uniprot id: A0A060NRL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1458426:SMCB RS03660
gene id: 1458426:SMCB_RS03660
uniprot id: A0A060NTV2
names: Similarity
messages: Belongs to the TPP enzyme family.

1458426:SMCB RS05635
gene id: 1458426:SMCB_RS05635
uniprot id: A0A060NV18
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family.
messages: Part of the 50S ribosomal subunit.

1458426:SMCB RS04025
gene id: 1458426:SMCB_RS04025
uniprot id: A0A060NU08
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS07330
gene id: 1458426:SMCB_RS07330
uniprot id: A0A060NMD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1458426:SMCB RS10805
gene id: 1458426:SMCB_RS10805
uniprot id: A0A060NZV4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1458426:SMCB RS07420
gene id: 1458426:SMCB_RS07420
uniprot id: A0A060NXU2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1458426:SMCB RS06145
gene id: 1458426:SMCB_RS06145
uniprot id: A0A060NX41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

1458426:SMCB RS10500
gene id: 1458426:SMCB_RS10500
uniprot id: A0A060NXW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1458426:SMCB RS05515
gene id: 1458426:SMCB_RS05515
uniprot id: A0A060NPT6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1458426:SMCB RS06965
gene id: 1458426:SMCB_RS06965
uniprot id: A0A060NQI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1458426:SMCB RS05330
gene id: 1458426:SMCB_RS05330
uniprot id: A0A060NNF9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1458426:SMCB RS10650
gene id: 1458426:SMCB_RS10650
uniprot id: A0A060NXY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1458426:SMCB RS05840
gene id: 1458426:SMCB_RS05840
uniprot id: A0A060NWZ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1458426:SMCB RS06125
gene id: 1458426:SMCB_RS06125
uniprot id: A0A060NQ25
names: Similarity
messages: Belongs to the peptidase S41A family.

1458426:SMCB RS06755
gene id: 1458426:SMCB_RS06755
uniprot id: A0A060NP79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1458426:SMCB RS07830
gene id: 1458426:SMCB_RS07830
uniprot id: A0A060NY45
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1458426:SMCB RS08875
gene id: 1458426:SMCB_RS08875
uniprot id: A0A060NRM8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458426:SMCB RS08910
gene id: 1458426:SMCB_RS08910
uniprot id: A0A060NQI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1458426:SMCB RS01320
gene id: 1458426:SMCB_RS01320
uniprot id: A0A060NUB2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1458426:SMCB RS08440
gene id: 1458426:SMCB_RS08440
uniprot id: A0A060NQA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1458426:SMCB RS08840
gene id: 1458426:SMCB_RS08840
uniprot id: A0A060NYP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1458426:SMCB RS12125
gene id: 1458426:SMCB_RS12125
uniprot id: A0A060NU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS00835
gene id: 1458426:SMCB_RS00835
uniprot id: A0A060NM11
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1458426:SMCB RS01970
gene id: 1458426:SMCB_RS01970
uniprot id: A0A060NUP3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1458426:SMCB RS05650
gene id: 1458426:SMCB_RS05650
uniprot id: A0A060NLH1
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1458426:SMCB RS01880
gene id: 1458426:SMCB_RS01880
uniprot id: A0A060NJQ8
names: Similarity
messages: Belongs to the type III secretion exporter family.

1458426:SMCB RS06780
gene id: 1458426:SMCB_RS06780
uniprot id: A0A060NP83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1458426:SMCB RS11695
gene id: 1458426:SMCB_RS11695
uniprot id: A0A060P0B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1458426:SMCB RS10835
gene id: 1458426:SMCB_RS10835
uniprot id: A0A060NSU6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1458426:SMCB RS11060
gene id: 1458426:SMCB_RS11060
uniprot id: A0A060NSX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1458426:SMCB RS05405
gene id: 1458426:SMCB_RS05405
uniprot id: A0A060NNI0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1458426:SMCB RS03610
gene id: 1458426:SMCB_RS03610
uniprot id: A0A060NTU4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1458426:SMCB RS06540
gene id: 1458426:SMCB_RS06540
uniprot id: A0A060NVF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1458426:SMCB RS11110
gene id: 1458426:SMCB_RS11110
uniprot id: A0A060NSY9
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1458426:SMCB RS04405
gene id: 1458426:SMCB_RS04405
uniprot id: A0A060NW33
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1458426:SMCB RS10130
gene id: 1458426:SMCB_RS10130
uniprot id: A0A060NSD5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1458426:SMCB RS05105
gene id: 1458426:SMCB_RS05105
uniprot id: A0A060NL60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458426:SMCB RS11105
gene id: 1458426:SMCB_RS11105
uniprot id: A0A060P000
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1458426:SMCB RS09185
gene id: 1458426:SMCB_RS09185
uniprot id: A0A060NWZ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1458426:SMCB RS07080
gene id: 1458426:SMCB_RS07080
uniprot id: A0A060NVR2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1458426:SMCB RS05920
gene id: 1458426:SMCB_RS05920
uniprot id: A0A060NPZ7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1458426:SMCB RS00245
gene id: 1458426:SMCB_RS00245
uniprot id: A0A060NRX2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1458426:SMCB RS05925
gene id: 1458426:SMCB_RS05925
uniprot id: A0A060NLL0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1458426:SMCB RS07625
gene id: 1458426:SMCB_RS07625
uniprot id: A0A060NW40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1458426:SMCB RS10605
gene id: 1458426:SMCB_RS10605
uniprot id: A0A060NZS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1458426:SMCB RS10115
gene id: 1458426:SMCB_RS10115
uniprot id: A0A060NR66
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1458426:SMCB RS11350
gene id: 1458426:SMCB_RS11350
uniprot id: A0A060NY89
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1458426:SMCB RS00235
gene id: 1458426:SMCB_RS00235
uniprot id: A0A060NJ74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1458426:SMCB RS11655
gene id: 1458426:SMCB_RS11655
uniprot id: A0A060NPR1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458426:SMCB RS07025
gene id: 1458426:SMCB_RS07025
uniprot id: A0A060NPD0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1458426:SMCB RS06095
gene id: 1458426:SMCB_RS06095
uniprot id: A0A060NX32
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1458426:SMCB RS08920
gene id: 1458426:SMCB_RS08920
uniprot id: A0A060NYQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS08660
gene id: 1458426:SMCB_RS08660
uniprot id: A0A060NQD9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458426:SMCB RS04010
gene id: 1458426:SMCB_RS04010
uniprot id: A0A060NNU6
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1458426:SMCB RS04165
gene id: 1458426:SMCB_RS04165
uniprot id: A0A060NMR5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS11775
gene id: 1458426:SMCB_RS11775
uniprot id: A0A060NTB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1458426:SMCB RS00390
gene id: 1458426:SMCB_RS00390
uniprot id: A0A060NKR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1458426:SMCB RS09875
gene id: 1458426:SMCB_RS09875
uniprot id: A0A060NZ97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1458426:SMCB RS06720
gene id: 1458426:SMCB_RS06720
uniprot id: A0A060NQD7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1458426:SMCB RS02540
gene id: 1458426:SMCB_RS02540
uniprot id: A0A060NK12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1458426:SMCB RS05980
gene id: 1458426:SMCB_RS05980
uniprot id: A0A060NLL8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1458426:SMCB RS08945
gene id: 1458426:SMCB_RS08945
uniprot id: A0A060NYR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1458426:SMCB RS08005
gene id: 1458426:SMCB_RS08005
uniprot id: A0A060NMU8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458426:SMCB RS07760
gene id: 1458426:SMCB_RS07760
uniprot id: A0A060NQZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1458426:SMCB RS01875
gene id: 1458426:SMCB_RS01875
uniprot id: A0A060NMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1458426:SMCB RS07040
gene id: 1458426:SMCB_RS07040
uniprot id: A0A060NQJ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1458426:SMCB RS02260
gene id: 1458426:SMCB_RS02260
uniprot id: A0A060NMR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1458426:SMCB RS09520
gene id: 1458426:SMCB_RS09520
uniprot id: A0A060NRZ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1458426:SMCB RS05570
gene id: 1458426:SMCB_RS05570
uniprot id: A0A060NPU2
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1458426:SMCB RS00140
gene id: 1458426:SMCB_RS00140
uniprot id: A0A060NKL5
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1458426:SMCB RS06610
gene id: 1458426:SMCB_RS06610
uniprot id: A0A060NP57
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS04945
gene id: 1458426:SMCB_RS04945
uniprot id: A0A060NWD4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1458426:SMCB RS06075
gene id: 1458426:SMCB_RS06075
uniprot id: A0A060NQ18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1458426:SMCB RS10885
gene id: 1458426:SMCB_RS10885
uniprot id: A0A060NSV2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1458426:SMCB RS03855
gene id: 1458426:SMCB_RS03855
uniprot id: A0A060NTY1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1458426:SMCB RS00300
gene id: 1458426:SMCB_RS00300
uniprot id: A0A060NRY4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1458426:SMCB RS11210
gene id: 1458426:SMCB_RS11210
uniprot id: A0A060NT07
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1458426:SMCB RS02710
gene id: 1458426:SMCB_RS02710
uniprot id: A0A060NV52
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1458426:SMCB RS03040
gene id: 1458426:SMCB_RS03040
uniprot id: A0A060NNC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1458426:SMCB RS09965
gene id: 1458426:SMCB_RS09965
uniprot id: A0A060NR33
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1458426:SMCB RS10185
gene id: 1458426:SMCB_RS10185
uniprot id: A0A060NP10
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS10430
gene id: 1458426:SMCB_RS10430
uniprot id: A0A060NZP4
names: Similarity
messages: Belongs to the HypD family.

1458426:SMCB RS00225
gene id: 1458426:SMCB_RS00225
uniprot id: A0A060NTQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1458426:SMCB RS07270
gene id: 1458426:SMCB_RS07270
uniprot id: A0A060NXR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1458426:SMCB RS09430
gene id: 1458426:SMCB_RS09430
uniprot id: A0A060NQR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1458426:SMCB RS00405
gene id: 1458426:SMCB_RS00405
uniprot id: A0A060NLQ2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1458426:SMCB RS10705
gene id: 1458426:SMCB_RS10705
uniprot id: A0A060NZT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1458426:SMCB RS08165
gene id: 1458426:SMCB_RS08165
uniprot id: A0A060NYD2
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1458426:SMCB RS04085
gene id: 1458426:SMCB_RS04085
uniprot id: A0A060NNV8
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1458426:SMCB RS04000
gene id: 1458426:SMCB_RS04000
uniprot id: A0A060NU05
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

1458426:SMCB RS07130
gene id: 1458426:SMCB_RS07130
uniprot id: A0A060NXN5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1458426:SMCB RS04550
gene id: 1458426:SMCB_RS04550
uniprot id: A0A060NMX5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1458426:SMCB RS07535
gene id: 1458426:SMCB_RS07535
uniprot id: A0A060NMI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1458426:SMCB RS02770
gene id: 1458426:SMCB_RS02770
uniprot id: A0A060NLY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1458426:SMCB RS09010
gene id: 1458426:SMCB_RS09010
uniprot id: A0A060NQJ6
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1458426:SMCB RS00700
gene id: 1458426:SMCB_RS00700
uniprot id: A0A060NU23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1458426:SMCB RS05220
gene id: 1458426:SMCB_RS05220
uniprot id: A0A060NPJ0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS02020
gene id: 1458426:SMCB_RS02020
uniprot id: A0A060NUQ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1458426:SMCB RS05045
gene id: 1458426:SMCB_RS05045
uniprot id: A0A060NWG0
names: Similarity
messages: Belongs to the UPF0434 family.

1458426:SMCB RS10960
gene id: 1458426:SMCB_RS10960
uniprot id: A0A060NSW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1458426:SMCB RS11015
gene id: 1458426:SMCB_RS11015
uniprot id: A0A060NPF2
names: Similarity
messages: Belongs to the MotB family.

1458426:SMCB RS08250
gene id: 1458426:SMCB_RS08250
uniprot id: A0A060NWJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS11600
gene id: 1458426:SMCB_RS11600
uniprot id: A0A060NT82
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1458426:SMCB RS06480
gene id: 1458426:SMCB_RS06480
uniprot id: A0A060NLU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1458426:SMCB RS06750
gene id: 1458426:SMCB_RS06750
uniprot id: A0A060NM03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1458426:SMCB RS02895
gene id: 1458426:SMCB_RS02895
uniprot id: A0A060NM17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1458426:SMCB RS04995
gene id: 1458426:SMCB_RS04995
uniprot id: A0A060NWE6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1458426:SMCB RS03895
gene id: 1458426:SMCB_RS03895
uniprot id: A0A060NML7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458426:SMCB RS07910
gene id: 1458426:SMCB_RS07910
uniprot id: A0A060NPY8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1458426:SMCB RS08575
gene id: 1458426:SMCB_RS08575
uniprot id: A0A060NRG9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1458426:SMCB RS05765
gene id: 1458426:SMCB_RS05765
uniprot id: A0A060NPX3
names: Similarity
messages: Belongs to the peptidase A31 family.

1458426:SMCB RS01310
gene id: 1458426:SMCB_RS01310
uniprot id: A0A060NL61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1458426:SMCB RS04775
gene id: 1458426:SMCB_RS04775
uniprot id: A0A060NN25
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1458426:SMCB RS02550
gene id: 1458426:SMCB_RS02550
uniprot id: A0A060NT78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1458426:SMCB RS08965
gene id: 1458426:SMCB_RS08965
uniprot id: A0A060NWV5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1458426:SMCB RS04240
gene id: 1458426:SMCB_RS04240
uniprot id: A0A060NMS6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1458426:SMCB RS06620
gene id: 1458426:SMCB_RS06620
uniprot id: A0A060NXD1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1458426:SMCB RS09590
gene id: 1458426:SMCB_RS09590
uniprot id: A0A060NZ39
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1458426:SMCB RS11480
gene id: 1458426:SMCB_RS11480
uniprot id: A0A060NPN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates influx of magnesium ions.
messages: Membrane

1458426:SMCB RS10830
gene id: 1458426:SMCB_RS10830
uniprot id: A0A060NZV8
names: Subcellular Location Annotation
messages: Cytoplasm

1458426:SMCB RS08080
gene id: 1458426:SMCB_RS08080
uniprot id: A0A060NQ46
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

1458426:SMCB RS02360
gene id: 1458426:SMCB_RS02360
uniprot id: A0A060NMT4
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1458426:SMCB RS07195
gene id: 1458426:SMCB_RS07195
uniprot id: A0A060NXP4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1458426:SMCB RS03025
gene id: 1458426:SMCB_RS03025
uniprot id: A0A060NM75
names: Similarity
messages: Belongs to the histone deacetylase family.

1458426:SMCB RS05665
gene id: 1458426:SMCB_RS05665
uniprot id: A0A060NWX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1458426:SMCB RS01575
gene id: 1458426:SMCB_RS01575
uniprot id: A0A060NMD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1458426:SMCB RS06490
gene id: 1458426:SMCB_RS06490
uniprot id: A0A060NVE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1458426:SMCB RS02680
gene id: 1458426:SMCB_RS02680
uniprot id: A0A060NLV3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1458426:SMCB RS04765
gene id: 1458426:SMCB_RS04765
uniprot id: A0A060NP81
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1458426:SMCB RS00515
gene id: 1458426:SMCB_RS00515
uniprot id: A0A060NS59
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS10815
gene id: 1458426:SMCB_RS10815
uniprot id: A0A060NPC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458426:SMCB RS07095
gene id: 1458426:SMCB_RS07095
uniprot id: A0A060NM76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1458426:SMCB RS06805
gene id: 1458426:SMCB_RS06805
uniprot id: A0A060NP86
names: Similarity
messages: Belongs to the RelE toxin family.

1458426:SMCB RS01470
gene id: 1458426:SMCB_RS01470
uniprot id: A0A060NMB7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458426:SMCB RS02580
gene id: 1458426:SMCB_RS02580
uniprot id: A0A060NT83
names: Similarity
messages: Belongs to the UPF0234 family.

1458426:SMCB RS08240
gene id: 1458426:SMCB_RS08240
uniprot id: A0A060NRC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1458426:SMCB RS06595
gene id: 1458426:SMCB_RS06595
uniprot id: A0A060NXC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1458426:SMCB RS07735
gene id: 1458426:SMCB_RS07735
uniprot id: A0A060NQZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1458426:SMCB RS11865
gene id: 1458426:SMCB_RS11865
uniprot id: A0A060NTC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1458426:SMCB RS10910
gene id: 1458426:SMCB_RS10910
uniprot id: A0A060NSV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

1458426:SMCB RS07030
gene id: 1458426:SMCB_RS07030
uniprot id: A0A060NVQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1458426:SMCB RS00630
gene id: 1458426:SMCB_RS00630
uniprot id: A0A060NLX7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458426:SMCB RS10900
gene id: 1458426:SMCB_RS10900
uniprot id: A0A060NY24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1458426:SMCB RS09565
gene id: 1458426:SMCB_RS09565
uniprot id: A0A060NZ33
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1458426:SMCB RS03695
gene id: 1458426:SMCB_RS03695
uniprot id: A0A060NNN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1458426:SMCB RS01550
gene id: 1458426:SMCB_RS01550
uniprot id: A0A060NMD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1458426:SMCB RS06275
gene id: 1458426:SMCB_RS06275
uniprot id: A0A060NQ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458426:SMCB RS09765
gene id: 1458426:SMCB_RS09765
uniprot id: A0A060NQZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1458426:SMCB RS06605
gene id: 1458426:SMCB_RS06605
uniprot id: A0A060NLX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1458426:SMCB RS11050
gene id: 1458426:SMCB_RS11050
uniprot id: A0A060NY48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458426:SMCB RS01350
gene id: 1458426:SMCB_RS01350
uniprot id: A0A060NM93
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1458426:SMCB RS00015
gene id: 1458426:SMCB_RS00015
uniprot id: A0A060NJ41
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1458426:SMCB RS00610
gene id: 1458426:SMCB_RS00610
uniprot id: A0A060NKX6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1458426:SMCB RS03720
gene id: 1458426:SMCB_RS03720
uniprot id: A0A060NNN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1458426:SMCB RS08380
gene id: 1458426:SMCB_RS08380
uniprot id: A0A060NRE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1458426:SMCB RS11270
gene id: 1458426:SMCB_RS11270
uniprot id: A0A060NRV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS11905
gene id: 1458426:SMCB_RS11905
uniprot id: A0A060NYI2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS11595
gene id: 1458426:SMCB_RS11595
uniprot id: A0A060P092
names: Similarity
messages: Belongs to the CsoS2 family.

1458426:SMCB RS10250
gene id: 1458426:SMCB_RS10250
uniprot id: A0A060NSG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1458426:SMCB RS11435
gene id: 1458426:SMCB_RS11435
uniprot id: A0A060NPM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1458426:SMCB RS06455
gene id: 1458426:SMCB_RS06455
uniprot id: A0A060NLU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1458426:SMCB RS02080
gene id: 1458426:SMCB_RS02080
uniprot id: A0A060NLH3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1458426:SMCB RS11055
gene id: 1458426:SMCB_RS11055
uniprot id: A0A060NZZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1458426:SMCB RS09375
gene id: 1458426:SMCB_RS09375
uniprot id: A0A060NNH6
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1458426:SMCB RS08835
gene id: 1458426:SMCB_RS08835
uniprot id: A0A060NWT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1458426:SMCB RS07435
gene id: 1458426:SMCB_RS07435
uniprot id: A0A060NPL6
names: Similarity
messages: Belongs to the LOG family.

1458426:SMCB RS10615
gene id: 1458426:SMCB_RS10615
uniprot id: A0A060NPA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1458426:SMCB RS05565
gene id: 1458426:SMCB_RS05565
uniprot id: A0A060NWV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1458426:SMCB RS11365
gene id: 1458426:SMCB_RS11365
uniprot id: A0A060NPK9
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS01345
gene id: 1458426:SMCB_RS01345
uniprot id: A0A060NUB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1458426:SMCB RS00600
gene id: 1458426:SMCB_RS00600
uniprot id: A0A060NLX3
names: Similarity
messages: Belongs to the GSP E family.

1458426:SMCB RS04260
gene id: 1458426:SMCB_RS04260
uniprot id: A0A060NKR5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1458426:SMCB RS11240
gene id: 1458426:SMCB_RS11240
uniprot id: A0A060NPJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS00080
gene id: 1458426:SMCB_RS00080
uniprot id: A0A060NLH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1458426:SMCB RS08245
gene id: 1458426:SMCB_RS08245
uniprot id: A0A060NQ71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1458426:SMCB RS01790
gene id: 1458426:SMCB_RS01790
uniprot id: A0A060NSR5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1458426:SMCB RS06220
gene id: 1458426:SMCB_RS06220
uniprot id: A0A060NX53
names: Similarity
messages: Belongs to the TPP enzyme family.

1458426:SMCB RS04530
gene id: 1458426:SMCB_RS04530
uniprot id: A0A060NUA5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1458426:SMCB RS11640
gene id: 1458426:SMCB_RS11640
uniprot id: A0A060NYD9
names: Similarity
messages: Belongs to the transketolase family.

1458426:SMCB RS00220
gene id: 1458426:SMCB_RS00220
uniprot id: A0A060NRW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1458426:SMCB RS11615
gene id: 1458426:SMCB_RS11615
uniprot id: A0A060NYD4
names: Similarity
messages: Belongs to the pyruvate kinase family.

1458426:SMCB RS11630
gene id: 1458426:SMCB_RS11630
uniprot id: A0A060NPQ5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS04175
gene id: 1458426:SMCB_RS04175
uniprot id: A0A060NVY7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1458426:SMCB RS09385
gene id: 1458426:SMCB_RS09385
uniprot id: A0A060NX33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1458426:SMCB RS10655
gene id: 1458426:SMCB_RS10655
uniprot id: A0A060NZT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1458426:SMCB RS00925
gene id: 1458426:SMCB_RS00925
uniprot id: A0A060NSC2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458426:SMCB RS06645
gene id: 1458426:SMCB_RS06645
uniprot id: A0A060NXD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1458426:SMCB RS02155
gene id: 1458426:SMCB_RS02155
uniprot id: A0A060NMQ0
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1458426:SMCB RS00070
gene id: 1458426:SMCB_RS00070
uniprot id: A0A060NRT1
names: Similarity
messages: Belongs to the UPF0250 family.

1458426:SMCB RS05915
gene id: 1458426:SMCB_RS05915
uniprot id: A0A060NX06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1458426:SMCB RS08255
gene id: 1458426:SMCB_RS08255
uniprot id: A0A060NYE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1458426:SMCB RS01260
gene id: 1458426:SMCB_RS01260
uniprot id: A0A060NL54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1458426:SMCB RS06960
gene id: 1458426:SMCB_RS06960
uniprot id: A0A060NXK3
names: Similarity
messages: Belongs to the YfgM family.

1458426:SMCB RS05795
gene id: 1458426:SMCB_RS05795
uniprot id: A0A060NLJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1458426:SMCB RS00200
gene id: 1458426:SMCB_RS00200
uniprot id: A0A060NTP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1458426:SMCB RS08690
gene id: 1458426:SMCB_RS08690
uniprot id: A0A060NWR2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1458426:SMCB RS06790
gene id: 1458426:SMCB_RS06790
uniprot id: A0A060NXG6
names: Similarity
messages: Belongs to the UPF0145 family.

1458426:SMCB RS10875
gene id: 1458426:SMCB_RS10875
uniprot id: A0A060NY20
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458426:SMCB RS09000
gene id: 1458426:SMCB_RS09000
uniprot id: A0A060NRQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1458426:SMCB RS06495
gene id: 1458426:SMCB_RS06495
uniprot id: A0A060NXA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1458426:SMCB RS09170
gene id: 1458426:SMCB_RS09170
uniprot id: A0A060NRT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1458426:SMCB RS06170
gene id: 1458426:SMCB_RS06170
uniprot id: A0A060NX43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1458426:SMCB RS07660
gene id: 1458426:SMCB_RS07660
uniprot id: A0A060NQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1458426:SMCB RS11610
gene id: 1458426:SMCB_RS11610
uniprot id: A0A060NS07
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458426:SMCB RS02495
gene id: 1458426:SMCB_RS02495
uniprot id: A0A060NLR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1458426:SMCB RS01485
gene id: 1458426:SMCB_RS01485
uniprot id: A0A060NSK8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1458426:SMCB RS05120
gene id: 1458426:SMCB_RS05120
uniprot id: A0A060NWH9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1458426:SMCB RS08280
gene id: 1458426:SMCB_RS08280
uniprot id: A0A060NRC8
names: Similarity
messages: Belongs to the TrpF family.

1458426:SMCB RS09980
gene id: 1458426:SMCB_RS09980
uniprot id: A0A060NS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1458426:SMCB RS06475
gene id: 1458426:SMCB_RS06475
uniprot id: A0A060NQ90
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1458426:SMCB RS05975
gene id: 1458426:SMCB_RS05975
uniprot id: A0A060NQ03
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1458426:SMCB RS00640
gene id: 1458426:SMCB_RS00640
uniprot id: A0A060NKX9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS07190
gene id: 1458426:SMCB_RS07190
uniprot id: A0A060NVT6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1458426:SMCB RS02875
gene id: 1458426:SMCB_RS02875
uniprot id: A0A060NTF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1458426:SMCB RS02055
gene id: 1458426:SMCB_RS02055
uniprot id: A0A060NJT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1458426:SMCB RS00460
gene id: 1458426:SMCB_RS00460
uniprot id: A0A060NJA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1458426:SMCB RS05855
gene id: 1458426:SMCB_RS05855
uniprot id: A0A060NNT2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1458426:SMCB RS04135
gene id: 1458426:SMCB_RS04135
uniprot id: A0A060NNW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1458426:SMCB RS04295
gene id: 1458426:SMCB_RS04295
uniprot id: A0A060NU58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1458426:SMCB RS02140
gene id: 1458426:SMCB_RS02140
uniprot id: A0A060NLI5
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1458426:SMCB RS07120
gene id: 1458426:SMCB_RS07120
uniprot id: A0A060NPF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1458426:SMCB RS11190
gene id: 1458426:SMCB_RS11190
uniprot id: A0A060NPI4
names: Similarity
messages: Belongs to the thioredoxin family.

1458426:SMCB RS09390
gene id: 1458426:SMCB_RS09390
uniprot id: A0A060NZ03
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS01885
gene id: 1458426:SMCB_RS01885
uniprot id: A0A060NLE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1458426:SMCB RS07520
gene id: 1458426:SMCB_RS07520
uniprot id: A0A060NW16
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1458426:SMCB RS11620
gene id: 1458426:SMCB_RS11620
uniprot id: A0A060P096
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458426:SMCB RS06235
gene id: 1458426:SMCB_RS06235
uniprot id: A0A060NNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1458426:SMCB RS05335
gene id: 1458426:SMCB_RS05335
uniprot id: A0A060NUT9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS06950
gene id: 1458426:SMCB_RS06950
uniprot id: A0A060NM44
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1458426:SMCB RS10730
gene id: 1458426:SMCB_RS10730
uniprot id: A0A060NZU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS08160
gene id: 1458426:SMCB_RS08160
uniprot id: A0A060NWH6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1458426:SMCB RS08600
gene id: 1458426:SMCB_RS08600
uniprot id: A0A060NRH3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1458426:SMCB RS06380
gene id: 1458426:SMCB_RS06380
uniprot id: A0A060NLT0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1458426:SMCB RS10070
gene id: 1458426:SMCB_RS10070
uniprot id: A0A060NXJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS00110
gene id: 1458426:SMCB_RS00110
uniprot id: A0A060NJ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1458426:SMCB RS07200
gene id: 1458426:SMCB_RS07200
uniprot id: A0A060NQM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1458426:SMCB RS00365
gene id: 1458426:SMCB_RS00365
uniprot id: A0A060NKR2
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS11115
gene id: 1458426:SMCB_RS11115
uniprot id: A0A060NPH0
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1458426:SMCB RS00435
gene id: 1458426:SMCB_RS00435
uniprot id: A0A060NJA3
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS10025
gene id: 1458426:SMCB_RS10025
uniprot id: A0A060NZD3
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1458426:SMCB RS00685
gene id: 1458426:SMCB_RS00685
uniprot id: A0A060NJE2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1458426:SMCB RS10410
gene id: 1458426:SMCB_RS10410
uniprot id: A0A060NSJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1458426:SMCB RS02235
gene id: 1458426:SMCB_RS02235
uniprot id: A0A060NMR4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1458426:SMCB RS06090
gene id: 1458426:SMCB_RS06090
uniprot id: A0A060NV87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1458426:SMCB RS06670
gene id: 1458426:SMCB_RS06670
uniprot id: A0A060NXE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1458426:SMCB RS10010
gene id: 1458426:SMCB_RS10010
uniprot id: A0A060NNW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1458426:SMCB RS08515
gene id: 1458426:SMCB_RS08515
uniprot id: A0A060NWN5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1458426:SMCB RS09755
gene id: 1458426:SMCB_RS09755
uniprot id: A0A060NS42
names: Similarity
messages: Belongs to the DprA/Smf family.

1458426:SMCB RS04890
gene id: 1458426:SMCB_RS04890
uniprot id: A0A060NUI6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS05880
gene id: 1458426:SMCB_RS05880
uniprot id: A0A060NNT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1458426:SMCB RS03075
gene id: 1458426:SMCB_RS03075
uniprot id: A0A060NTL4
names: Similarity
messages: Belongs to the CIA30 family.

1458426:SMCB RS10175
gene id: 1458426:SMCB_RS10175
uniprot id: A0A060NZH0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS08410
gene id: 1458426:SMCB_RS08410
uniprot id: A0A060NN10
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS06515
gene id: 1458426:SMCB_RS06515
uniprot id: A0A060NP40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1458426:SMCB RS10435
gene id: 1458426:SMCB_RS10435
uniprot id: A0A060NSM4
names: Similarity
messages: Belongs to the HupF/HypC family.

1458426:SMCB RS05245
gene id: 1458426:SMCB_RS05245
uniprot id: A0A060NPJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1458426:SMCB RS09770
gene id: 1458426:SMCB_RS09770
uniprot id: A0A060NXB9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1458426:SMCB RS01445
gene id: 1458426:SMCB_RS01445
uniprot id: A0A060NMB3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1458426:SMCB RS10225
gene id: 1458426:SMCB_RS10225
uniprot id: A0A060NSF4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS07935
gene id: 1458426:SMCB_RS07935
uniprot id: A0A060NQ12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1458426:SMCB RS03155
gene id: 1458426:SMCB_RS03155
uniprot id: A0A060NKB1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1458426:SMCB RS11145
gene id: 1458426:SMCB_RS11145
uniprot id: A0A060NRT3
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS04360
gene id: 1458426:SMCB_RS04360
uniprot id: A0A060NP09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1458426:SMCB RS00890
gene id: 1458426:SMCB_RS00890
uniprot id: A0A060NJG1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1458426:SMCB RS09705
gene id: 1458426:SMCB_RS09705
uniprot id: A0A060NS28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.
messages: The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ).

1458426:SMCB RS09880
gene id: 1458426:SMCB_RS09880
uniprot id: A0A060NS71
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1458426:SMCB RS04900
gene id: 1458426:SMCB_RS04900
uniprot id: A0A060NPA8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1458426:SMCB RS08360
gene id: 1458426:SMCB_RS08360
uniprot id: A0A060NN01
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1458426:SMCB RS07680
gene id: 1458426:SMCB_RS07680
uniprot id: A0A060NY07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1458426:SMCB RS02870
gene id: 1458426:SMCB_RS02870
uniprot id: A0A060NM12
names: Similarity
messages: Belongs to the GARS family.

1458426:SMCB RS06905
gene id: 1458426:SMCB_RS06905
uniprot id: A0A060NPA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1458426:SMCB RS06440
gene id: 1458426:SMCB_RS06440
uniprot id: A0A060NVD9
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS07410
gene id: 1458426:SMCB_RS07410
uniprot id: A0A060NPL3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS00210
gene id: 1458426:SMCB_RS00210
uniprot id: A0A060NJ71
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1458426:SMCB RS07720
gene id: 1458426:SMCB_RS07720
uniprot id: A0A060NPT1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1458426:SMCB RS10050
gene id: 1458426:SMCB_RS10050
uniprot id: A0A060NZD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1458426:SMCB RS03105
gene id: 1458426:SMCB_RS03105
uniprot id: A0A060NKA5
names: Similarity
messages: Belongs to the HsdR family.

1458426:SMCB RS04675
gene id: 1458426:SMCB_RS04675
uniprot id: A0A060NN03
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1458426:SMCB RS01925
gene id: 1458426:SMCB_RS01925
uniprot id: A0A060NMK4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1458426:SMCB RS02845
gene id: 1458426:SMCB_RS02845
uniprot id: A0A060NM05
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1458426:SMCB RS09050
gene id: 1458426:SMCB_RS09050
uniprot id: A0A060NRR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1458426:SMCB RS08605
gene id: 1458426:SMCB_RS08605
uniprot id: A0A060NN40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1458426:SMCB RS01000
gene id: 1458426:SMCB_RS01000
uniprot id: A0A060NSD4
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS10000
gene id: 1458426:SMCB_RS10000
uniprot id: A0A060NZC7
names: Similarity
messages: Belongs to the creatininase superfamily.

1458426:SMCB RS02905
gene id: 1458426:SMCB_RS02905
uniprot id: A0A060NVA0
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS02950
gene id: 1458426:SMCB_RS02950
uniprot id: A0A060NM52
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1458426:SMCB RS04275
gene id: 1458426:SMCB_RS04275
uniprot id: A0A060NW07
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1458426:SMCB RS04335
gene id: 1458426:SMCB_RS04335
uniprot id: A0A060NKS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1458426:SMCB RS07335
gene id: 1458426:SMCB_RS07335
uniprot id: A0A060NPJ7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1458426:SMCB RS04830
gene id: 1458426:SMCB_RS04830
uniprot id: A0A060NN36
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS09655
gene id: 1458426:SMCB_RS09655
uniprot id: A0A060NNN2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1458426:SMCB RS01015
gene id: 1458426:SMCB_RS01015
uniprot id: A0A060NM38
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1458426:SMCB RS06530
gene id: 1458426:SMCB_RS06530
uniprot id: A0A060NQA0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1458426:SMCB RS06305
gene id: 1458426:SMCB_RS06305
uniprot id: A0A060NLR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1458426:SMCB RS07205
gene id: 1458426:SMCB_RS07205
uniprot id: A0A060NMA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1458426:SMCB RS01585
gene id: 1458426:SMCB_RS01585
uniprot id: A0A060NLA3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1458426:SMCB RS08915
gene id: 1458426:SMCB_RS08915
uniprot id: A0A060NWU6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1458426:SMCB RS07615
gene id: 1458426:SMCB_RS07615
uniprot id: A0A060NMK2
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1458426:SMCB RS00415
gene id: 1458426:SMCB_RS00415
uniprot id: A0A060NKS2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS10905
gene id: 1458426:SMCB_RS10905
uniprot id: A0A060NZW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

1458426:SMCB RS01165
gene id: 1458426:SMCB_RS01165
uniprot id: A0A060NU90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1458426:SMCB RS08585
gene id: 1458426:SMCB_RS08585
uniprot id: A0A060NQC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1458426:SMCB RS01645
gene id: 1458426:SMCB_RS01645
uniprot id: A0A060NUH9
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1458426:SMCB RS00105
gene id: 1458426:SMCB_RS00105
uniprot id: A0A060NLI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1458426:SMCB RS06340
gene id: 1458426:SMCB_RS06340
uniprot id: A0A060NVC5
names: Similarity
messages: Belongs to the MoaD family.

1458426:SMCB RS06885
gene id: 1458426:SMCB_RS06885
uniprot id: A0A060NVM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS05690
gene id: 1458426:SMCB_RS05690
uniprot id: A0A060NWX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1458426:SMCB RS10015
gene id: 1458426:SMCB_RS10015
uniprot id: A0A060NR42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1458426:SMCB RS05280
gene id: 1458426:SMCB_RS05280
uniprot id: A0A060NNE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1458426:SMCB RS08815
gene id: 1458426:SMCB_RS08815
uniprot id: A0A060NYN7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1458426:SMCB RS00455
gene id: 1458426:SMCB_RS00455
uniprot id: A0A060NLR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1458426:SMCB RS03600
gene id: 1458426:SMCB_RS03600
uniprot id: A0A060NKH1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1458426:SMCB RS01920
gene id: 1458426:SMCB_RS01920
uniprot id: A0A060NUN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1458426:SMCB RS11515
gene id: 1458426:SMCB_RS11515
uniprot id: A0A060NYB7
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1458426:SMCB RS11970
gene id: 1458426:SMCB_RS11970
uniprot id: A0A060NPW9
names: Similarity
messages: Belongs to the RelE toxin family.

1458426:SMCB RS07695
gene id: 1458426:SMCB_RS07695
uniprot id: A0A060NPS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1458426:SMCB RS00075
gene id: 1458426:SMCB_RS00075
uniprot id: A0A060NTK9
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS00295
gene id: 1458426:SMCB_RS00295
uniprot id: A0A060NKP6
names: Similarity
messages: Belongs to the YoeB family.

1458426:SMCB RS06430
gene id: 1458426:SMCB_RS06430
uniprot id: A0A060NLT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1458426:SMCB RS05085
gene id: 1458426:SMCB_RS05085
uniprot id: A0A060NN90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1458426:SMCB RS11605
gene id: 1458426:SMCB_RS11605
uniprot id: A0A060NPQ2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1458426:SMCB RS03850
gene id: 1458426:SMCB_RS03850
uniprot id: A0A060NMK9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1458426:SMCB RS04065
gene id: 1458426:SMCB_RS04065
uniprot id: A0A060NKN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1458426:SMCB RS11685
gene id: 1458426:SMCB_RS11685
uniprot id: A0A060NS18
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1458426:SMCB RS05735
gene id: 1458426:SMCB_RS05735
uniprot id: A0A060NWY3
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS06745
gene id: 1458426:SMCB_RS06745
uniprot id: A0A060NQE2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1458426:SMCB RS10680
gene id: 1458426:SMCB_RS10680
uniprot id: A0A060NZT6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1458426:SMCB RS11225
gene id: 1458426:SMCB_RS11225
uniprot id: A0A060NY73
names: Similarity
messages: Belongs to the NTE family.

1458426:SMCB RS03990
gene id: 1458426:SMCB_RS03990
uniprot id: A0A060NKL9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1458426:SMCB RS02255
gene id: 1458426:SMCB_RS02255
uniprot id: A0A060NUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1458426:SMCB RS05320
gene id: 1458426:SMCB_RS05320
uniprot id: A0A060NPL0
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1458426:SMCB RS11045
gene id: 1458426:SMCB_RS11045
uniprot id: A0A060NRR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458426:SMCB RS05615
gene id: 1458426:SMCB_RS05615
uniprot id: A0A060NWW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1458426:SMCB RS00190
gene id: 1458426:SMCB_RS00190
uniprot id: A0A060NKM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1458426:SMCB RS00165
gene id: 1458426:SMCB_RS00165
uniprot id: A0A060NKM0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1458426:SMCB RS09300
gene id: 1458426:SMCB_RS09300
uniprot id: A0A060NNF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

1458426:SMCB RS04915
gene id: 1458426:SMCB_RS04915
uniprot id: A0A060NUJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458426:SMCB RS05420
gene id: 1458426:SMCB_RS05420
uniprot id: A0A060NPN6
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS11165
gene id: 1458426:SMCB_RS11165
uniprot id: A0A060NPH9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1458426:SMCB RS07725
gene id: 1458426:SMCB_RS07725
uniprot id: A0A060NW66
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1458426:SMCB RS07570
gene id: 1458426:SMCB_RS07570
uniprot id: A0A060NW30
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1458426:SMCB RS09450
gene id: 1458426:SMCB_RS09450
uniprot id: A0A060NNI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS04950
gene id: 1458426:SMCB_RS04950
uniprot id: A0A060NPC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1458426:SMCB RS08675
gene id: 1458426:SMCB_RS08675
uniprot id: A0A060NRI6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS09350
gene id: 1458426:SMCB_RS09350
uniprot id: A0A060NNG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Homododecamer. Tetramer of trimer.
messages: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.

1458426:SMCB RS11370
gene id: 1458426:SMCB_RS11370
uniprot id: A0A060NRW8
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS04970
gene id: 1458426:SMCB_RS04970
uniprot id: A0A060NWE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1458426:SMCB RS04660
gene id: 1458426:SMCB_RS04660
uniprot id: A0A060NP66
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1458426:SMCB RS08620
gene id: 1458426:SMCB_RS08620
uniprot id: A0A060NYK0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1458426:SMCB RS02830
gene id: 1458426:SMCB_RS02830
uniprot id: A0A060NV83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1458426:SMCB RS08610
gene id: 1458426:SMCB_RS08610
uniprot id: A0A060NQD0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1458426:SMCB RS01385
gene id: 1458426:SMCB_RS01385
uniprot id: A0A060NSI9
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1458426:SMCB RS06290
gene id: 1458426:SMCB_RS06290
uniprot id: A0A060NVB7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1458426:SMCB RS07595
gene id: 1458426:SMCB_RS07595
uniprot id: A0A060NW35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1458426:SMCB RS01430
gene id: 1458426:SMCB_RS01430
uniprot id: A0A060NL82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1458426:SMCB RS08465
gene id: 1458426:SMCB_RS08465
uniprot id: A0A060NQA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS01035
gene id: 1458426:SMCB_RS01035
uniprot id: A0A060NU70
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1458426:SMCB RS02630
gene id: 1458426:SMCB_RS02630
uniprot id: A0A060NV25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1458426:SMCB RS05620
gene id: 1458426:SMCB_RS05620
uniprot id: A0A060NPV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1458426:SMCB RS05005
gene id: 1458426:SMCB_RS05005
uniprot id: A0A060NL39
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1458426:SMCB RS07430
gene id: 1458426:SMCB_RS07430
uniprot id: A0A060NMF8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1458426:SMCB RS10660
gene id: 1458426:SMCB_RS10660
uniprot id: A0A060NSS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1458426:SMCB RS08120
gene id: 1458426:SMCB_RS08120
uniprot id: A0A060NRA2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1458426:SMCB RS01170
gene id: 1458426:SMCB_RS01170
uniprot id: A0A060NM62
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1458426:SMCB RS06360
gene id: 1458426:SMCB_RS06360
uniprot id: A0A060NP15
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1458426:SMCB RS07865
gene id: 1458426:SMCB_RS07865
uniprot id: A0A060NPX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1458426:SMCB RS09750
gene id: 1458426:SMCB_RS09750
uniprot id: A0A060NZ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1458426:SMCB RS06160
gene id: 1458426:SMCB_RS06160
uniprot id: A0A060NNY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1458426:SMCB RS04655
gene id: 1458426:SMCB_RS04655
uniprot id: A0A060NW81
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS09340
gene id: 1458426:SMCB_RS09340
uniprot id: A0A060NYZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1458426:SMCB RS06120
gene id: 1458426:SMCB_RS06120
uniprot id: A0A060NX36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1458426:SMCB RS11730
gene id: 1458426:SMCB_RS11730
uniprot id: A0A060NPS3
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1458426:SMCB RS04935
gene id: 1458426:SMCB_RS04935
uniprot id: A0A060NN56
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1458426:SMCB RS09165
gene id: 1458426:SMCB_RS09165
uniprot id: A0A060NYV9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458426:SMCB RS08615
gene id: 1458426:SMCB_RS08615
uniprot id: A0A060NWQ1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1458426:SMCB RS07505
gene id: 1458426:SMCB_RS07505
uniprot id: A0A060NQT7
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1458426:SMCB RS00020
gene id: 1458426:SMCB_RS00020
uniprot id: A0A060NKJ5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1458426:SMCB RS05455
gene id: 1458426:SMCB_RS05455
uniprot id: A0A060NUZ0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1458426:SMCB RS11575
gene id: 1458426:SMCB_RS11575
uniprot id: A0A060NT77
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1458426:SMCB RS10060
gene id: 1458426:SMCB_RS10060
uniprot id: A0A060NNY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1458426:SMCB RS05730
gene id: 1458426:SMCB_RS05730
uniprot id: A0A060NV35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1458426:SMCB RS05215
gene id: 1458426:SMCB_RS05215
uniprot id: A0A060NWK6
names: Similarity
messages: Belongs to the peptidase M1 family.

1458426:SMCB RS06580
gene id: 1458426:SMCB_RS06580
uniprot id: A0A060NLW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1458426:SMCB RS07285
gene id: 1458426:SMCB_RS07285
uniprot id: A0A060NPI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1458426:SMCB RS03275
gene id: 1458426:SMCB_RS03275
uniprot id: A0A060NNG8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1458426:SMCB RS07250
gene id: 1458426:SMCB_RS07250
uniprot id: A0A060NXQ5
names: Subcellular Location Annotation
messages: Cytoplasm

1458426:SMCB RS09860
gene id: 1458426:SMCB_RS09860
uniprot id: A0A060NNT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1458426:SMCB RS03805
gene id: 1458426:SMCB_RS03805
uniprot id: A0A060NMK1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458426:SMCB RS08405
gene id: 1458426:SMCB_RS08405
uniprot id: A0A060NRE6
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1458426:SMCB RS06590
gene id: 1458426:SMCB_RS06590
uniprot id: A0A060NVG6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS09470
gene id: 1458426:SMCB_RS09470
uniprot id: A0A060NRZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1458426:SMCB RS04965
gene id: 1458426:SMCB_RS04965
uniprot id: A0A060NUK6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1458426:SMCB RS04990
gene id: 1458426:SMCB_RS04990
uniprot id: A0A060NUL1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1458426:SMCB RS07325
gene id: 1458426:SMCB_RS07325
uniprot id: A0A060NQP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1458426:SMCB RS00940
gene id: 1458426:SMCB_RS00940
uniprot id: A0A060NJG6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458426:SMCB RS01690
gene id: 1458426:SMCB_RS01690
uniprot id: A0A060NSP3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1458426:SMCB RS01280
gene id: 1458426:SMCB_RS01280
uniprot id: A0A060NJJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1458426:SMCB RS01360
gene id: 1458426:SMCB_RS01360
uniprot id: A0A060NSI5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1458426:SMCB RS02225
gene id: 1458426:SMCB_RS02225
uniprot id: A0A060NT04
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1458426:SMCB RS00780
gene id: 1458426:SMCB_RS00780
uniprot id: A0A060NU35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1458426:SMCB RS06715
gene id: 1458426:SMCB_RS06715
uniprot id: A0A060NXF2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1458426:SMCB RS07500
gene id: 1458426:SMCB_RS07500
uniprot id: A0A060NXV9
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS07510
gene id: 1458426:SMCB_RS07510
uniprot id: A0A060NMH6
names: Similarity
messages: Belongs to the DEAD box helicase family.

1458426:SMCB RS01275
gene id: 1458426:SMCB_RS01275
uniprot id: A0A060NM80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1458426:SMCB RS01815
gene id: 1458426:SMCB_RS01815
uniprot id: A0A060NSS0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1458426:SMCB RS01590
gene id: 1458426:SMCB_RS01590
uniprot id: A0A060NSM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1458426:SMCB RS06825
gene id: 1458426:SMCB_RS06825
uniprot id: A0A060NM19
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458426:SMCB RS00310
gene id: 1458426:SMCB_RS00310
uniprot id: A0A060NLN0
names: Similarity
messages: Belongs to the CcdB toxin family.

1458426:SMCB RS09850
gene id: 1458426:SMCB_RS09850
uniprot id: A0A060NZ91
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1458426:SMCB RS05610
gene id: 1458426:SMCB_RS05610
uniprot id: A0A060NV14
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1458426:SMCB RS02160
gene id: 1458426:SMCB_RS02160
uniprot id: A0A060NJU7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1458426:SMCB RS09335
gene id: 1458426:SMCB_RS09335
uniprot id: A0A060NX23
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1458426:SMCB RS06315
gene id: 1458426:SMCB_RS06315
uniprot id: A0A060NVC1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS02885
gene id: 1458426:SMCB_RS02885
uniprot id: A0A060NN65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1458426:SMCB RS05365
gene id: 1458426:SMCB_RS05365
uniprot id: A0A060NWP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1458426:SMCB RS04590
gene id: 1458426:SMCB_RS04590
uniprot id: A0A060NP51
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1458426:SMCB RS03630
gene id: 1458426:SMCB_RS03630
uniprot id: A0A060NMH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458426:SMCB RS11465
gene id: 1458426:SMCB_RS11465
uniprot id: A0A060NRY5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1458426:SMCB RS04185
gene id: 1458426:SMCB_RS04185
uniprot id: A0A060NKQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1458426:SMCB RS10080
gene id: 1458426:SMCB_RS10080
uniprot id: A0A060NSC3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS08015
gene id: 1458426:SMCB_RS08015
uniprot id: A0A060NWF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

1458426:SMCB RS10475
gene id: 1458426:SMCB_RS10475
uniprot id: A0A060NXW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1458426:SMCB RS09695
gene id: 1458426:SMCB_RS09695
uniprot id: A0A060NXA1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1458426:SMCB RS08855
gene id: 1458426:SMCB_RS08855
uniprot id: A0A060NQH3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1458426:SMCB RS08695
gene id: 1458426:SMCB_RS08695
uniprot id: A0A060NYL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1458426:SMCB RS05425
gene id: 1458426:SMCB_RS05425
uniprot id: A0A060NLC8
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS08265
gene id: 1458426:SMCB_RS08265
uniprot id: A0A060NMY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.

1458426:SMCB RS01945
gene id: 1458426:SMCB_RS01945
uniprot id: A0A060NUN9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1458426:SMCB RS03665
gene id: 1458426:SMCB_RS03665
uniprot id: A0A060NVP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1458426:SMCB RS08225
gene id: 1458426:SMCB_RS08225
uniprot id: A0A060NQ68
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

1458426:SMCB RS07665
gene id: 1458426:SMCB_RS07665
uniprot id: A0A060NML3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1458426:SMCB RS08665
gene id: 1458426:SMCB_RS08665
uniprot id: A0A060NWR0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1458426:SMCB RS06785
gene id: 1458426:SMCB_RS06785
uniprot id: A0A060NVK4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1458426:SMCB RS09260
gene id: 1458426:SMCB_RS09260
uniprot id: A0A060NX08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS03685
gene id: 1458426:SMCB_RS03685
uniprot id: A0A060NTV7
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1458426:SMCB RS02430
gene id: 1458426:SMCB_RS02430
uniprot id: A0A060NUX7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1458426:SMCB RS10005
gene id: 1458426:SMCB_RS10005
uniprot id: A0A060NSA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1458426:SMCB RS06575
gene id: 1458426:SMCB_RS06575
uniprot id: A0A060NQB0
names: Similarity
messages: Belongs to the skp family.

1458426:SMCB RS05235
gene id: 1458426:SMCB_RS05235
uniprot id: A0A060NUS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1458426:SMCB RS00975
gene id: 1458426:SMCB_RS00975
uniprot id: A0A060NSD0
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1458426:SMCB RS06165
gene id: 1458426:SMCB_RS06165
uniprot id: A0A060NV99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1458426:SMCB RS10090
gene id: 1458426:SMCB_RS10090
uniprot id: A0A060NR59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1458426:SMCB RS10215
gene id: 1458426:SMCB_RS10215
uniprot id: A0A060NXM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1458426:SMCB RS10195
gene id: 1458426:SMCB_RS10195
uniprot id: A0A060NR85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1458426:SMCB RS00605
gene id: 1458426:SMCB_RS00605
uniprot id: A0A060NJD6
names: Similarity
messages: Belongs to the GSP E family.

1458426:SMCB RS08150
gene id: 1458426:SMCB_RS08150
uniprot id: A0A060NMW8
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1458426:SMCB RS04825
gene id: 1458426:SMCB_RS04825
uniprot id: A0A060NL07
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

1458426:SMCB RS00205
gene id: 1458426:SMCB_RS00205
uniprot id: A0A060NLK5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1458426:SMCB RS05525
gene id: 1458426:SMCB_RS05525
uniprot id: A0A060NNN4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1458426:SMCB RS00095
gene id: 1458426:SMCB_RS00095
uniprot id: A0A060NRT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1458426:SMCB RS00500
gene id: 1458426:SMCB_RS00500
uniprot id: A0A060NLV7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1458426:SMCB RS01700
gene id: 1458426:SMCB_RS01700
uniprot id: A0A060NMG1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1458426:SMCB RS10590
gene id: 1458426:SMCB_RS10590
uniprot id: A0A060NP98
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1458426:SMCB RS07380
gene id: 1458426:SMCB_RS07380
uniprot id: A0A060NME4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1458426:SMCB RS02625
gene id: 1458426:SMCB_RS02625
uniprot id: A0A060NT95
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS01565
gene id: 1458426:SMCB_RS01565
uniprot id: A0A060NSL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

1458426:SMCB RS09730
gene id: 1458426:SMCB_RS09730
uniprot id: A0A060NS35
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1458426:SMCB RS08445
gene id: 1458426:SMCB_RS08445
uniprot id: A0A060NWM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1458426:SMCB RS09795
gene id: 1458426:SMCB_RS09795
uniprot id: A0A060NXC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1458426:SMCB RS00100
gene id: 1458426:SMCB_RS00100
uniprot id: A0A060NTL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1458426:SMCB RS03295
gene id: 1458426:SMCB_RS03295
uniprot id: A0A060NVI7
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

1458426:SMCB RS01110
gene id: 1458426:SMCB_RS01110
uniprot id: A0A060NSF0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1458426:SMCB RS10720
gene id: 1458426:SMCB_RS10720
uniprot id: A0A060NRL8
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1458426:SMCB RS08975
gene id: 1458426:SMCB_RS08975
uniprot id: A0A060NRP7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1458426:SMCB RS08880
gene id: 1458426:SMCB_RS08880
uniprot id: A0A060NN80
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1458426:SMCB RS00675
gene id: 1458426:SMCB_RS00675
uniprot id: A0A060NU21
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1458426:SMCB RS06375
gene id: 1458426:SMCB_RS06375
uniprot id: A0A060NQ72
names: Similarity
messages: Belongs to the threonine synthase family.

1458426:SMCB RS08370
gene id: 1458426:SMCB_RS08370
uniprot id: A0A060NWL0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1458426:SMCB RS08950
gene id: 1458426:SMCB_RS08950
uniprot id: A0A060NRP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1458426:SMCB RS02475
gene id: 1458426:SMCB_RS02475
uniprot id: A0A060NT61
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1458426:SMCB RS07730
gene id: 1458426:SMCB_RS07730
uniprot id: A0A060NY21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1458426:SMCB RS05585
gene id: 1458426:SMCB_RS05585
uniprot id: A0A060NV11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1458426:SMCB RS07345
gene id: 1458426:SMCB_RS07345
uniprot id: A0A060NXS7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1458426:SMCB RS04790
gene id: 1458426:SMCB_RS04790
uniprot id: A0A060NWA4
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1458426:SMCB RS05625
gene id: 1458426:SMCB_RS05625
uniprot id: A0A060NLG8
names: Similarity
messages: Belongs to the thioredoxin family.

1458426:SMCB RS02865
gene id: 1458426:SMCB_RS02865
uniprot id: A0A060NK68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1458426:SMCB RS05590
gene id: 1458426:SMCB_RS05590
uniprot id: A0A060NWW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1458426:SMCB RS09315
gene id: 1458426:SMCB_RS09315
uniprot id: A0A060NYY7
names: Similarity
messages: Belongs to the glutamate synthase family.

1458426:SMCB RS06655
gene id: 1458426:SMCB_RS06655
uniprot id: A0A060NLY2
names: Similarity
messages: Belongs to the GbsR family.

1458426:SMCB RS00695
gene id: 1458426:SMCB_RS00695
uniprot id: A0A060NS84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1458426:SMCB RS02815
gene id: 1458426:SMCB_RS02815
uniprot id: A0A060NK60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1458426:SMCB RS00450
gene id: 1458426:SMCB_RS00450
uniprot id: A0A060NTW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1458426:SMCB RS11305
gene id: 1458426:SMCB_RS11305
uniprot id: A0A060P033
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS06110
gene id: 1458426:SMCB_RS06110
uniprot id: A0A060NNX3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1458426:SMCB RS04255
gene id: 1458426:SMCB_RS04255
uniprot id: A0A060NNZ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1458426:SMCB RS00535
gene id: 1458426:SMCB_RS00535
uniprot id: A0A060NKW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1458426:SMCB RS08305
gene id: 1458426:SMCB_RS08305
uniprot id: A0A060NRD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1458426:SMCB RS01435
gene id: 1458426:SMCB_RS01435
uniprot id: A0A060NSK0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1458426:SMCB RS10725
gene id: 1458426:SMCB_RS10725
uniprot id: A0A060NXZ6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1458426:SMCB RS03485
gene id: 1458426:SMCB_RS03485
uniprot id: A0A060NTS4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1458426:SMCB RS05960
gene id: 1458426:SMCB_RS05960
uniprot id: A0A060NNU8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1458426:SMCB RS04305
gene id: 1458426:SMCB_RS04305
uniprot id: A0A060NP00
names: Similarity
messages: Belongs to the peptidase M16 family.

1458426:SMCB RS05075
gene id: 1458426:SMCB_RS05075
uniprot id: A0A060NPF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1458426:SMCB RS01705
gene id: 1458426:SMCB_RS01705
uniprot id: A0A060NJN8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1458426:SMCB RS01570
gene id: 1458426:SMCB_RS01570
uniprot id: A0A060NUG1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1458426:SMCB RS01175
gene id: 1458426:SMCB_RS01175
uniprot id: A0A060NJI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1458426:SMCB RS01315
gene id: 1458426:SMCB_RS01315
uniprot id: A0A060NSI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1458426:SMCB RS01060
gene id: 1458426:SMCB_RS01060
uniprot id: A0A060NU73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1458426:SMCB RS01745
gene id: 1458426:SMCB_RS01745
uniprot id: A0A060NUJ8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1458426:SMCB RS05810
gene id: 1458426:SMCB_RS05810
uniprot id: A0A060NV47
names: Similarity
messages: Belongs to the aspartokinase family.

1458426:SMCB RS08990
gene id: 1458426:SMCB_RS08990
uniprot id: A0A060NWW0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1458426:SMCB RS07415
gene id: 1458426:SMCB_RS07415
uniprot id: A0A060NVZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1458426:SMCB RS04685
gene id: 1458426:SMCB_RS04685
uniprot id: A0A060NW86
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1458426:SMCB RS02035
gene id: 1458426:SMCB_RS02035
uniprot id: A0A060NLG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1458426:SMCB RS00135
gene id: 1458426:SMCB_RS00135
uniprot id: A0A060NJ59
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS08905
gene id: 1458426:SMCB_RS08905
uniprot id: A0A060NN84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

1458426:SMCB RS04035
gene id: 1458426:SMCB_RS04035
uniprot id: A0A060NNU9
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS06450
gene id: 1458426:SMCB_RS06450
uniprot id: A0A060NQ85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1458426:SMCB RS10045
gene id: 1458426:SMCB_RS10045
uniprot id: A0A060NXI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1458426:SMCB RS06000
gene id: 1458426:SMCB_RS06000
uniprot id: A0A060NQ07
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1458426:SMCB RS07530
gene id: 1458426:SMCB_RS07530
uniprot id: A0A060NQU3
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1458426:SMCB RS02040
gene id: 1458426:SMCB_RS02040
uniprot id: A0A060NSW4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1458426:SMCB RS04855
gene id: 1458426:SMCB_RS04855
uniprot id: A0A060NL12
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1458426:SMCB RS04245
gene id: 1458426:SMCB_RS04245
uniprot id: A0A060NU49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1458426:SMCB RS09180
gene id: 1458426:SMCB_RS09180
uniprot id: A0A060NQM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1458426:SMCB RS10085
gene id: 1458426:SMCB_RS10085
uniprot id: A0A060NNY8
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1458426:SMCB RS00720
gene id: 1458426:SMCB_RS00720
uniprot id: A0A060NJE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1458426:SMCB RS04070
gene id: 1458426:SMCB_RS04070
uniprot id: A0A060NMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1458426:SMCB RS04535
gene id: 1458426:SMCB_RS04535
uniprot id: A0A060NW58
names: Subcellular Location Annotation
messages: Membrane

1458426:SMCB RS04230
gene id: 1458426:SMCB_RS04230
uniprot id: A0A060NNY5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1458426:SMCB RS02165
gene id: 1458426:SMCB_RS02165
uniprot id: A0A060NLJ0
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.