1441930:Z042 RS10690
gene id: 1441930:Z042_RS10690
uniprot id: W0L5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS01055
gene id: 1441930:Z042_RS01055
uniprot id: W0LAB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS02340
gene id: 1441930:Z042_RS02340
uniprot id: W0LDT9
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS06130
gene id: 1441930:Z042_RS06130
uniprot id: W0LCC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1441930:Z042 RS22270
gene id: 1441930:Z042_RS22270
uniprot id: W0LG31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

1441930:Z042 RS16680
gene id: 1441930:Z042_RS16680
uniprot id: W0LK49
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1441930:Z042 RS13315
gene id: 1441930:Z042_RS13315
uniprot id: W0L4G7
names: Similarity
messages: Belongs to the CcdB toxin family.

1441930:Z042 RS07790
gene id: 1441930:Z042_RS07790
uniprot id: W0L771
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

1441930:Z042 RS02715
gene id: 1441930:Z042_RS02715
uniprot id: W0LEY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS05055
gene id: 1441930:Z042_RS05055
uniprot id: W0LCT4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS18390
gene id: 1441930:Z042_RS18390
uniprot id: W0LEA8
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

1441930:Z042 RS12940
gene id: 1441930:Z042_RS12940
uniprot id: W0L9G4
names: Similarity
messages: Belongs to the AHA1 family.

1441930:Z042 RS23440
gene id: 1441930:Z042_RS23440
uniprot id: W0LBA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1441930:Z042 RS04830
gene id: 1441930:Z042_RS04830
uniprot id: W0LCJ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1441930:Z042 RS08120
gene id: 1441930:Z042_RS08120
uniprot id: W0LAV7
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family. AlsE subfamily.
messages: Catalyzes the reversible epimerization of D-allulose 6-phosphate to D-fructose 6-phosphate. Can also catalyze with lower efficiency the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1441930:Z042 RS18495
gene id: 1441930:Z042_RS18495
uniprot id: W0LJ70
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1441930:Z042 RS00215
gene id: 1441930:Z042_RS00215
uniprot id: W0LG64
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS09590
gene id: 1441930:Z042_RS09590
uniprot id: W0L6A7
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS16850
gene id: 1441930:Z042_RS16850
uniprot id: W0LEM7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1441930:Z042 RS02660
gene id: 1441930:Z042_RS02660
uniprot id: W0L9W9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1441930:Z042 RS16310
gene id: 1441930:Z042_RS16310
uniprot id: W0LJC5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS03700
gene id: 1441930:Z042_RS03700
uniprot id: W0LD61
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS04480
gene id: 1441930:Z042_RS04480
uniprot id: W0L8W7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1441930:Z042 RS22555
gene id: 1441930:Z042_RS22555
uniprot id: W0LG81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1441930:Z042 RS08620
gene id: 1441930:Z042_RS08620
uniprot id: W0LAN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1441930:Z042 RS15830
gene id: 1441930:Z042_RS15830
uniprot id: W0LFM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1441930:Z042 RS03190
gene id: 1441930:Z042_RS03190
uniprot id: W0LEQ9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1441930:Z042 RS15430
gene id: 1441930:Z042_RS15430
uniprot id: W0L7L6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

1441930:Z042 RS12825
gene id: 1441930:Z042_RS12825
uniprot id: W0L4N3
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1441930:Z042 RS16020
gene id: 1441930:Z042_RS16020
uniprot id: W0LKH6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS12660
gene id: 1441930:Z042_RS12660
uniprot id: W0L4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1441930:Z042 RS24335
gene id: 1441930:Z042_RS24335
uniprot id: W0LF11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1441930:Z042 RS14290
gene id: 1441930:Z042_RS14290
uniprot id: W0L439
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS21055
gene id: 1441930:Z042_RS21055
uniprot id: W0LCJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS04005
gene id: 1441930:Z042_RS04005
uniprot id: W0LE87
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS07400
gene id: 1441930:Z042_RS07400
uniprot id: W0L772
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS19650
gene id: 1441930:Z042_RS19650
uniprot id: W0LHL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1441930:Z042 RS18365
gene id: 1441930:Z042_RS18365
uniprot id: W0LEB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1441930:Z042 RS16285
gene id: 1441930:Z042_RS16285
uniprot id: W0LJC9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS00895
gene id: 1441930:Z042_RS00895
uniprot id: W0LAE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1441930:Z042 RS04620
gene id: 1441930:Z042_RS04620
uniprot id: W0LCP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm
messages: Homotetramer.

1441930:Z042 RS16760
gene id: 1441930:Z042_RS16760
uniprot id: W0LF22
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1441930:Z042 RS21230
gene id: 1441930:Z042_RS21230
uniprot id: W0LCT5
names: Similarity
messages: Belongs to the intimin/invasin family.

1441930:Z042 RS20660
gene id: 1441930:Z042_RS20660
uniprot id: W0LH69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1441930:Z042 RS08195
gene id: 1441930:Z042_RS08195
uniprot id: W0LB71
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1441930:Z042 RS06100
gene id: 1441930:Z042_RS06100
uniprot id: W0L7X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1441930:Z042 RS08505
gene id: 1441930:Z042_RS08505
uniprot id: W0LBY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

1441930:Z042 RS21780
gene id: 1441930:Z042_RS21780
uniprot id: W0LGP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1441930:Z042 RS21710
gene id: 1441930:Z042_RS21710
uniprot id: W0LCK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1441930:Z042 RS06995
gene id: 1441930:Z042_RS06995
uniprot id: W0L7L2
names: Similarity
messages: Belongs to the pirin family.

1441930:Z042 RS14045
gene id: 1441930:Z042_RS14045
uniprot id: W0L7Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1441930:Z042 RS07785
gene id: 1441930:Z042_RS07785
uniprot id: W0LBE6
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1441930:Z042 RS20160
gene id: 1441930:Z042_RS20160
uniprot id: W0LH68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS19145
gene id: 1441930:Z042_RS19145
uniprot id: W0LHN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1441930:Z042 RS18265
gene id: 1441930:Z042_RS18265
uniprot id: W0LED2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1441930:Z042 RS00985
gene id: 1441930:Z042_RS00985
uniprot id: W0LES9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1441930:Z042 RS01150
gene id: 1441930:Z042_RS01150
uniprot id: W0LEF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS09215
gene id: 1441930:Z042_RS09215
uniprot id: W0LAB3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1441930:Z042 RS09225
gene id: 1441930:Z042_RS09225
uniprot id: W0LAM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1441930:Z042 RS06880
gene id: 1441930:Z042_RS06880
uniprot id: W0LBW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

1441930:Z042 RS11040
gene id: 1441930:Z042_RS11040
uniprot id: W0L9P9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1441930:Z042 RS15190
gene id: 1441930:Z042_RS15190
uniprot id: W0L7Q5
names: Similarity
messages: Belongs to the LOG family.

1441930:Z042 RS07690
gene id: 1441930:Z042_RS07690
uniprot id: W0L788
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS06335
gene id: 1441930:Z042_RS06335
uniprot id: W0L7S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

1441930:Z042 RS14630
gene id: 1441930:Z042_RS14630
uniprot id: W0L7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1441930:Z042 RS06430
gene id: 1441930:Z042_RS06430
uniprot id: W0L7W9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1441930:Z042 RS07340
gene id: 1441930:Z042_RS07340
uniprot id: W0LCH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1441930:Z042 RS24215
gene id: 1441930:Z042_RS24215
uniprot id: W0LFE9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1441930:Z042 RS10655
gene id: 1441930:Z042_RS10655
uniprot id: W0LAQ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS10205
gene id: 1441930:Z042_RS10205
uniprot id: W0L9T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

1441930:Z042 RS05970
gene id: 1441930:Z042_RS05970
uniprot id: W0LC16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1441930:Z042 RS21830
gene id: 1441930:Z042_RS21830
uniprot id: W0LGN4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1441930:Z042 RS20750
gene id: 1441930:Z042_RS20750
uniprot id: W0LD17
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1441930:Z042 RS12910
gene id: 1441930:Z042_RS12910
uniprot id: W0L4M1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS03205
gene id: 1441930:Z042_RS03205
uniprot id: W0LDR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzzB/Cld/Rol family.
messages: Cell inner membrane
messages: Membrane
messages: Modulates the polysaccharide chain length of enterobacterial common antigen (ECA).
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

1441930:Z042 RS01280
gene id: 1441930:Z042_RS01280
uniprot id: W0LAH7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1441930:Z042 RS07580
gene id: 1441930:Z042_RS07580
uniprot id: W0LB55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1441930:Z042 RS15320
gene id: 1441930:Z042_RS15320
uniprot id: W0L7N3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1441930:Z042 RS11735
gene id: 1441930:Z042_RS11735
uniprot id: W0L529
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1441930:Z042 RS00935
gene id: 1441930:Z042_RS00935
uniprot id: W0LET6
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1441930:Z042 RS23970
gene id: 1441930:Z042_RS23970
uniprot id: W0LB16
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

1441930:Z042 RS08770
gene id: 1441930:Z042_RS08770
uniprot id: W0LAX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1441930:Z042 RS10090
gene id: 1441930:Z042_RS10090
uniprot id: W0LA68
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1441930:Z042 RS15805
gene id: 1441930:Z042_RS15805
uniprot id: A0A0D4ZYH4
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1441930:Z042 RS05070
gene id: 1441930:Z042_RS05070
uniprot id: W0LCF2
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS03165
gene id: 1441930:Z042_RS03165
uniprot id: W0LER1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 56 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
messages: Cell inner membrane

1441930:Z042 RS22150
gene id: 1441930:Z042_RS22150
uniprot id: W0LC13
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1441930:Z042 RS15515
gene id: 1441930:Z042_RS15515
uniprot id: W0L3E6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1441930:Z042 RS22005
gene id: 1441930:Z042_RS22005
uniprot id: W0LGK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1441930:Z042 RS10715
gene id: 1441930:Z042_RS10715
uniprot id: W0L5I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS00945
gene id: 1441930:Z042_RS00945
uniprot id: W0LFT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1441930:Z042 RS08615
gene id: 1441930:Z042_RS08615
uniprot id: W0LBW5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

1441930:Z042 RS17455
gene id: 1441930:Z042_RS17455
uniprot id: W0LEP5
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1441930:Z042 RS22940
gene id: 1441930:Z042_RS22940
uniprot id: W0LBV4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS10175
gene id: 1441930:Z042_RS10175
uniprot id: W0LAZ1
names: Similarity
messages: Belongs to the aldose epimerase family.

1441930:Z042 RS07085
gene id: 1441930:Z042_RS07085
uniprot id: W0L7C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

1441930:Z042 RS04865
gene id: 1441930:Z042_RS04865
uniprot id: W0LCV8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.

1441930:Z042 RS21445
gene id: 1441930:Z042_RS21445
uniprot id: W0LHP3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1441930:Z042 RS10515
gene id: 1441930:Z042_RS10515
uniprot id: W0L5M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1441930:Z042 RS11825
gene id: 1441930:Z042_RS11825
uniprot id: W0L519
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1441930:Z042 RS22980
gene id: 1441930:Z042_RS22980
uniprot id: W0LFQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1441930:Z042 RS10060
gene id: 1441930:Z042_RS10060
uniprot id: W0L5U3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

1441930:Z042 RS02185
gene id: 1441930:Z042_RS02185
uniprot id: W0LAH7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1441930:Z042 RS06270
gene id: 1441930:Z042_RS06270
uniprot id: W0LBX1
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS16730
gene id: 1441930:Z042_RS16730
uniprot id: A0A0D4ZY85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell membrane

1441930:Z042 RS05835
gene id: 1441930:Z042_RS05835
uniprot id: W0L8A2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1441930:Z042 RS01570
gene id: 1441930:Z042_RS01570
uniprot id: W0LAD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1441930:Z042 RS01030
gene id: 1441930:Z042_RS01030
uniprot id: W0LAC1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS16745
gene id: 1441930:Z042_RS16745
uniprot id: W0LIS6
names: Function
names: Similarity
messages: Belongs to the glutathione peroxidase family. BtuE subfamily.
messages: Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.

1441930:Z042 RS23870
gene id: 1441930:Z042_RS23870
uniprot id: W0LF82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS19710
gene id: 1441930:Z042_RS19710
uniprot id: W0LIJ0
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1441930:Z042 RS10940
gene id: 1441930:Z042_RS10940
uniprot id: W0L9R7
names: Similarity
messages: Belongs to the VgrG protein family.

1441930:Z042 RS22680
gene id: 1441930:Z042_RS22680
uniprot id: W0LG60
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1441930:Z042 RS20495
gene id: 1441930:Z042_RS20495
uniprot id: W0LH10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1441930:Z042 RS14815
gene id: 1441930:Z042_RS14815
uniprot id: W0L8P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1441930:Z042 RS20765
gene id: 1441930:Z042_RS20765
uniprot id: W0LCP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1441930:Z042 RS19945
gene id: 1441930:Z042_RS19945
uniprot id: W0LDF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

1441930:Z042 RS05725
gene id: 1441930:Z042_RS05725
uniprot id: W0L832
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1441930:Z042 RS09875
gene id: 1441930:Z042_RS09875
uniprot id: W0LB53
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1441930:Z042 RS07775
gene id: 1441930:Z042_RS07775
uniprot id: W0LB14
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS12045
gene id: 1441930:Z042_RS12045
uniprot id: W0L8U6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1441930:Z042 RS21435
gene id: 1441930:Z042_RS21435
uniprot id: W0LGV5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1441930:Z042 RS02635
gene id: 1441930:Z042_RS02635
uniprot id: W0L9X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

1441930:Z042 RS20415
gene id: 1441930:Z042_RS20415
uniprot id: W0LHA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS20795
gene id: 1441930:Z042_RS20795
uniprot id: W0LH49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1441930:Z042 RS08945
gene id: 1441930:Z042_RS08945
uniprot id: W0LAU5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1441930:Z042 RS08780
gene id: 1441930:Z042_RS08780
uniprot id: W0LBT9
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS11390
gene id: 1441930:Z042_RS11390
uniprot id: W0L987
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1441930:Z042 RS02890
gene id: 1441930:Z042_RS02890
uniprot id: W0LEV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1441930:Z042 RS18930
gene id: 1441930:Z042_RS18930
uniprot id: A0A0D4ZYL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS02325
gene id: 1441930:Z042_RS02325
uniprot id: W0LE62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1441930:Z042 RS06300
gene id: 1441930:Z042_RS06300
uniprot id: W0LBW2
names: Similarity
messages: Belongs to the aspartokinase family.

1441930:Z042 RS12510
gene id: 1441930:Z042_RS12510
uniprot id: W0L9P6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

1441930:Z042 RS22640
gene id: 1441930:Z042_RS22640
uniprot id: W0LH48
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1441930:Z042 RS04715
gene id: 1441930:Z042_RS04715
uniprot id: W0L8S3
names: Similarity
messages: Belongs to the FBPase class 2 family.

1441930:Z042 RS22480
gene id: 1441930:Z042_RS22480
uniprot id: W0LBT2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1441930:Z042 RS04010
gene id: 1441930:Z042_RS04010
uniprot id: W0LD05
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS12505
gene id: 1441930:Z042_RS12505
uniprot id: W0L4T7
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS13385
gene id: 1441930:Z042_RS13385
uniprot id: W0L8K2
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1441930:Z042 RS06150
gene id: 1441930:Z042_RS06150
uniprot id: W0L7W4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1441930:Z042 RS18530
gene id: 1441930:Z042_RS18530
uniprot id: W0LDV3
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1441930:Z042 RS08350
gene id: 1441930:Z042_RS08350
uniprot id: W0LB40
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1441930:Z042 RS05300
gene id: 1441930:Z042_RS05300
uniprot id: W0LDK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1441930:Z042 RS04150
gene id: 1441930:Z042_RS04150
uniprot id: W0L8U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1441930:Z042 RS22250
gene id: 1441930:Z042_RS22250
uniprot id: W0LBW8
names: Similarity
messages: Belongs to the YkuD family.

1441930:Z042 RS06060
gene id: 1441930:Z042_RS06060
uniprot id: W0L857
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1441930:Z042 RS23860
gene id: 1441930:Z042_RS23860
uniprot id: W0LBG3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1441930:Z042 RS03025
gene id: 1441930:Z042_RS03025
uniprot id: W0L9Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1441930:Z042 RS10775
gene id: 1441930:Z042_RS10775
uniprot id: W0L5Q3
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.

1441930:Z042 RS16355
gene id: 1441930:Z042_RS16355
uniprot id: W0LJC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

1441930:Z042 RS08570
gene id: 1441930:Z042_RS08570
uniprot id: W0LAP7
names: Similarity
messages: Belongs to the YggT family.

1441930:Z042 RS22915
gene id: 1441930:Z042_RS22915
uniprot id: W0LBV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

1441930:Z042 RS21870
gene id: 1441930:Z042_RS21870
uniprot id: W0LGC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1441930:Z042 RS20920
gene id: 1441930:Z042_RS20920
uniprot id: W0LGS4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS17230
gene id: 1441930:Z042_RS17230
uniprot id: A0A0D4ZYI3
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS03235
gene id: 1441930:Z042_RS03235
uniprot id: W0L9M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1441930:Z042 RS09505
gene id: 1441930:Z042_RS09505
uniprot id: W0L6C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS18195
gene id: 1441930:Z042_RS18195
uniprot id: W0LI25
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS15040
gene id: 1441930:Z042_RS15040
uniprot id: W0L3I2
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1441930:Z042 RS22100
gene id: 1441930:Z042_RS22100
uniprot id: W0LC24
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS04645
gene id: 1441930:Z042_RS04645
uniprot id: W0LCN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1441930:Z042 RS24330
gene id: 1441930:Z042_RS24330
uniprot id: W0LG96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

1441930:Z042 RS22655
gene id: 1441930:Z042_RS22655
uniprot id: W0LG65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1441930:Z042 RS21795
gene id: 1441930:Z042_RS21795
uniprot id: W0LGD5
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS08515
gene id: 1441930:Z042_RS08515
uniprot id: W0L6N9
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1441930:Z042 RS02545
gene id: 1441930:Z042_RS02545
uniprot id: W0L9Y4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS05985
gene id: 1441930:Z042_RS05985
uniprot id: W0L873
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1441930:Z042 RS18605
gene id: 1441930:Z042_RS18605
uniprot id: W0LDU0
names: Similarity
messages: Belongs to the group II decarboxylase family.

1441930:Z042 RS21280
gene id: 1441930:Z042_RS21280
uniprot id: W0LCS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1441930:Z042 RS06050
gene id: 1441930:Z042_RS06050
uniprot id: W0L7X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1441930:Z042 RS16930
gene id: 1441930:Z042_RS16930
uniprot id: W0LEL2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS17360
gene id: 1441930:Z042_RS17360
uniprot id: W0LJR2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1441930:Z042 RS18485
gene id: 1441930:Z042_RS18485
uniprot id: W0LI67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1441930:Z042 RS17450
gene id: 1441930:Z042_RS17450
uniprot id: W0LIP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

1441930:Z042 RS06455
gene id: 1441930:Z042_RS06455
uniprot id: W0L7W3
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1441930:Z042 RS05065
gene id: 1441930:Z042_RS05065
uniprot id: W0LDP6
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1441930:Z042 RS00825
gene id: 1441930:Z042_RS00825
uniprot id: W0LEV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS18545
gene id: 1441930:Z042_RS18545
uniprot id: W0LJ61
names: Similarity
messages: Belongs to the MotB family.

1441930:Z042 RS23370
gene id: 1441930:Z042_RS23370
uniprot id: W0LFT8
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1441930:Z042 RS10765
gene id: 1441930:Z042_RS10765
uniprot id: W0L5H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

1441930:Z042 RS12075
gene id: 1441930:Z042_RS12075
uniprot id: W0L4V9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1441930:Z042 RS04855
gene id: 1441930:Z042_RS04855
uniprot id: W0LCI9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS07115
gene id: 1441930:Z042_RS07115
uniprot id: W0LBR8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1441930:Z042 RS24300
gene id: 1441930:Z042_RS24300
uniprot id: W0LB97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1441930:Z042 RS18335
gene id: 1441930:Z042_RS18335
uniprot id: W0LI95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1441930:Z042 RS21440
gene id: 1441930:Z042_RS21440
uniprot id: W0LCP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1441930:Z042 RS15310
gene id: 1441930:Z042_RS15310
uniprot id: W0L7B2
names: Similarity
messages: Belongs to the YciI family.

1441930:Z042 RS19235
gene id: 1441930:Z042_RS19235
uniprot id: W0LDW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS07795
gene id: 1441930:Z042_RS07795
uniprot id: W0LC88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS06375
gene id: 1441930:Z042_RS06375
uniprot id: W0LC57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1441930:Z042 RS09265
gene id: 1441930:Z042_RS09265
uniprot id: W0LAA3
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1441930:Z042 RS05830
gene id: 1441930:Z042_RS05830
uniprot id: W0LCH8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1441930:Z042 RS08090
gene id: 1441930:Z042_RS08090
uniprot id: W0LC38
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS14960
gene id: 1441930:Z042_RS14960
uniprot id: W0L3J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

1441930:Z042 RS05185
gene id: 1441930:Z042_RS05185
uniprot id: W0LDM5
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

1441930:Z042 RS14805
gene id: 1441930:Z042_RS14805
uniprot id: W0L7Z1
names: Similarity
messages: Belongs to the UPF0502 family.

1441930:Z042 RS09390
gene id: 1441930:Z042_RS09390
uniprot id: W0LAJ5
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1441930:Z042 RS17400
gene id: 1441930:Z042_RS17400
uniprot id: W0LIP8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1441930:Z042 RS04125
gene id: 1441930:Z042_RS04125
uniprot id: W0L8U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1441930:Z042 RS15470
gene id: 1441930:Z042_RS15470
uniprot id: W0L8A6
names: Similarity
messages: Belongs to the SUI1 family.

1441930:Z042 RS03705
gene id: 1441930:Z042_RS03705
uniprot id: W0L923
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1441930:Z042 RS08800
gene id: 1441930:Z042_RS08800
uniprot id: W0L6S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1441930:Z042 RS18855
gene id: 1441930:Z042_RS18855
uniprot id: W0LDP9
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS03810
gene id: 1441930:Z042_RS03810
uniprot id: W0L907
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1441930:Z042 RS13985
gene id: 1441930:Z042_RS13985
uniprot id: W0L480
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS23690
gene id: 1441930:Z042_RS23690
uniprot id: W0LGJ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS06950
gene id: 1441930:Z042_RS06950
uniprot id: W0L7E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1441930:Z042 RS09890
gene id: 1441930:Z042_RS09890
uniprot id: W0LAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1441930:Z042 RS11640
gene id: 1441930:Z042_RS11640
uniprot id: W0LA97
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

1441930:Z042 RS01675
gene id: 1441930:Z042_RS01675
uniprot id: W0LEH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CutA family.
messages: Binds 1 copper ion per subunit.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in resistance toward heavy metals.

1441930:Z042 RS06035
gene id: 1441930:Z042_RS06035
uniprot id: W0L864
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1441930:Z042 RS21225
gene id: 1441930:Z042_RS21225
uniprot id: W0LGY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

1441930:Z042 RS06590
gene id: 1441930:Z042_RS06590
uniprot id: W0LCX0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1441930:Z042 RS14600
gene id: 1441930:Z042_RS14600
uniprot id: W0L7R2
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS02530
gene id: 1441930:Z042_RS02530
uniprot id: W0LDQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1441930:Z042 RS14510
gene id: 1441930:Z042_RS14510
uniprot id: W0L8W8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1441930:Z042 RS12845
gene id: 1441930:Z042_RS12845
uniprot id: W0L4H3
names: Similarity
messages: Belongs to the UPF0265 family.

1441930:Z042 RS20550
gene id: 1441930:Z042_RS20550
uniprot id: W0LCT7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1441930:Z042 RS09140
gene id: 1441930:Z042_RS09140
uniprot id: W0LAN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1441930:Z042 RS09760
gene id: 1441930:Z042_RS09760
uniprot id: W0L5Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS03315
gene id: 1441930:Z042_RS03315
uniprot id: W0L9K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS04825
gene id: 1441930:Z042_RS04825
uniprot id: W0LDS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS04600
gene id: 1441930:Z042_RS04600
uniprot id: W0L8M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

1441930:Z042 RS22685
gene id: 1441930:Z042_RS22685
uniprot id: W0LBZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1441930:Z042 RS02460
gene id: 1441930:Z042_RS02460
uniprot id: W0L9P2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS18950
gene id: 1441930:Z042_RS18950
uniprot id: W0LHZ0
names: Function
names: Similarity
messages: Belongs to the TorD/DmsD family. DmsD subfamily.
messages: Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein.

1441930:Z042 RS18035
gene id: 1441930:Z042_RS18035
uniprot id: W0LI54
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1441930:Z042 RS06285
gene id: 1441930:Z042_RS06285
uniprot id: A0A0D4ZXH1
names: Function
names: Similarity
messages: Belongs to the bacterial-type ferredoxin family. FixX subfamily.
messages: Could be a 3Fe-4S cluster-containing protein.

1441930:Z042 RS10785
gene id: 1441930:Z042_RS10785
uniprot id: W0L9H1
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

1441930:Z042 RS04095
gene id: 1441930:Z042_RS04095
uniprot id: W0L8V4
names: Subunit
messages: Monomer.

1441930:Z042 RS07415
gene id: 1441930:Z042_RS07415
uniprot id: W0LCF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1441930:Z042 RS01190
gene id: 1441930:Z042_RS01190
uniprot id: W0LAJ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1441930:Z042 RS10565
gene id: 1441930:Z042_RS10565
uniprot id: W0L5L1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1441930:Z042 RS09210
gene id: 1441930:Z042_RS09210
uniprot id: W0LBI3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1441930:Z042 RS16370
gene id: 1441930:Z042_RS16370
uniprot id: W0LJ28
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1441930:Z042 RS15325
gene id: 1441930:Z042_RS15325
uniprot id: A0A0D4ZYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1441930:Z042 RS13930
gene id: 1441930:Z042_RS13930
uniprot id: W0L8C3
names: Similarity
messages: Belongs to the HypD family.

1441930:Z042 RS10705
gene id: 1441930:Z042_RS10705
uniprot id: W0LAP9
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

1441930:Z042 RS14870
gene id: 1441930:Z042_RS14870
uniprot id: W0L3R3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1441930:Z042 RS24320
gene id: 1441930:Z042_RS24320
uniprot id: W0LFD0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1441930:Z042 RS12705
gene id: 1441930:Z042_RS12705
uniprot id: W0L9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS15535
gene id: 1441930:Z042_RS15535
uniprot id: W0L390
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS10865
gene id: 1441930:Z042_RS10865
uniprot id: W0L5F5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1441930:Z042 RS02240
gene id: 1441930:Z042_RS02240
uniprot id: W0L9T2
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS18970
gene id: 1441930:Z042_RS18970
uniprot id: W0LDN0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS19615
gene id: 1441930:Z042_RS19615
uniprot id: W0LHE9
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS23075
gene id: 1441930:Z042_RS23075
uniprot id: W0LBT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1441930:Z042 RS21700
gene id: 1441930:Z042_RS21700
uniprot id: W0LC82
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. Cof family.
messages: Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).

1441930:Z042 RS08360
gene id: 1441930:Z042_RS08360
uniprot id: W0LBZ8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS24100
gene id: 1441930:Z042_RS24100
uniprot id: W0LAZ3
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS22835
gene id: 1441930:Z042_RS22835
uniprot id: W0LBX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS12100
gene id: 1441930:Z042_RS12100
uniprot id: W0L4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1441930:Z042 RS12585
gene id: 1441930:Z042_RS12585
uniprot id: W0L9N1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1441930:Z042 RS05030
gene id: 1441930:Z042_RS05030
uniprot id: W0LCU0
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1441930:Z042 RS16605
gene id: 1441930:Z042_RS16605
uniprot id: W0LIY6
names: Similarity
messages: Belongs to the pyruvate kinase family.

1441930:Z042 RS05495
gene id: 1441930:Z042_RS05495
uniprot id: W0LDH7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1441930:Z042 RS07350
gene id: 1441930:Z042_RS07350
uniprot id: W0L781
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1441930:Z042 RS23980
gene id: 1441930:Z042_RS23980
uniprot id: W0LBE3
names: Function
names: Similarity
messages: Belongs to the UxaA family.
messages: Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate (5-KDG).

1441930:Z042 RS02860
gene id: 1441930:Z042_RS02860
uniprot id: W0L9T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1441930:Z042 RS19155
gene id: 1441930:Z042_RS19155
uniprot id: W0LHW4
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1441930:Z042 RS07555
gene id: 1441930:Z042_RS07555
uniprot id: W0L747
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1441930:Z042 RS24085
gene id: 1441930:Z042_RS24085
uniprot id: W0LBC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS15755
gene id: 1441930:Z042_RS15755
uniprot id: W0LF81
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS16575
gene id: 1441930:Z042_RS16575
uniprot id: W0LEU9
names: Similarity
messages: Belongs to the CFA/CMAS family.

1441930:Z042 RS22085
gene id: 1441930:Z042_RS22085
uniprot id: W0LCC9
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1441930:Z042 RS18655
gene id: 1441930:Z042_RS18655
uniprot id: W0LDS9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1441930:Z042 RS18985
gene id: 1441930:Z042_RS18985
uniprot id: W0LIY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1441930:Z042 RS09625
gene id: 1441930:Z042_RS09625
uniprot id: W0LAF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
messages: In the N-terminal section; belongs to the 2-acyl-GPE acetyltransferase family.
messages: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.

1441930:Z042 RS17295
gene id: 1441930:Z042_RS17295
uniprot id: W0LEF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1441930:Z042 RS16660
gene id: 1441930:Z042_RS16660
uniprot id: A0A0D4ZXX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1441930:Z042 RS23625
gene id: 1441930:Z042_RS23625
uniprot id: W0LB72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1441930:Z042 RS18445
gene id: 1441930:Z042_RS18445
uniprot id: W0LJ79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1441930:Z042 RS23580
gene id: 1441930:Z042_RS23580
uniprot id: W0LGL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1441930:Z042 RS06705
gene id: 1441930:Z042_RS06705
uniprot id: A0A0D4ZY16
names: Similarity
messages: Belongs to the UPF0307 family.

1441930:Z042 RS01010
gene id: 1441930:Z042_RS01010
uniprot id: W0LES5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

1441930:Z042 RS12570
gene id: 1441930:Z042_RS12570
uniprot id: W0L4M3
names: Similarity
messages: Belongs to the CinA family.

1441930:Z042 RS04730
gene id: 1441930:Z042_RS04730
uniprot id: W0L8J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

1441930:Z042 RS17255
gene id: 1441930:Z042_RS17255
uniprot id: W0LET1
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family. NagK subfamily.
messages: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.

1441930:Z042 RS22970
gene id: 1441930:Z042_RS22970
uniprot id: W0LGY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

1441930:Z042 RS05275
gene id: 1441930:Z042_RS05275
uniprot id: W0LDL1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1441930:Z042 RS20965
gene id: 1441930:Z042_RS20965
uniprot id: W0LHV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1441930:Z042 RS12565
gene id: 1441930:Z042_RS12565
uniprot id: W0L8K5
names: Similarity
messages: Belongs to the catalase family.

1441930:Z042 RS09935
gene id: 1441930:Z042_RS09935
uniprot id: W0L5W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1441930:Z042 RS03680
gene id: 1441930:Z042_RS03680
uniprot id: W0L927
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS19910
gene id: 1441930:Z042_RS19910
uniprot id: W0LD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS19020
gene id: 1441930:Z042_RS19020
uniprot id: W0LDM3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1441930:Z042 RS09020
gene id: 1441930:Z042_RS09020
uniprot id: W0LBP4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1441930:Z042 RS13825
gene id: 1441930:Z042_RS13825
uniprot id: W0L809
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS22015
gene id: 1441930:Z042_RS22015
uniprot id: W0LHH2
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1441930:Z042 RS23605
gene id: 1441930:Z042_RS23605
uniprot id: W0LBK1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1441930:Z042 RS04640
gene id: 1441930:Z042_RS04640
uniprot id: W0LDW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
messages: Cell membrane
messages: Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).

1441930:Z042 RS18720
gene id: 1441930:Z042_RS18720
uniprot id: W0LJ35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1441930:Z042 RS17345
gene id: 1441930:Z042_RS17345
uniprot id: W0LEF0
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1441930:Z042 RS18065
gene id: 1441930:Z042_RS18065
uniprot id: W0LI50
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1441930:Z042 RS10535
gene id: 1441930:Z042_RS10535
uniprot id: W0L9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1441930:Z042 RS19645
gene id: 1441930:Z042_RS19645
uniprot id: W0LDA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS07105
gene id: 1441930:Z042_RS07105
uniprot id: W0LBE7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1441930:Z042 RS13540
gene id: 1441930:Z042_RS13540
uniprot id: W0L843
names: Similarity
messages: Belongs to the UPF0319 family.

1441930:Z042 RS16945
gene id: 1441930:Z042_RS16945
uniprot id: W0LJZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

1441930:Z042 RS10160
gene id: 1441930:Z042_RS10160
uniprot id: W0L5S6
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP).

1441930:Z042 RS08950
gene id: 1441930:Z042_RS08950
uniprot id: W0L6P6
names: Similarity
messages: Belongs to the TPP enzyme family.

1441930:Z042 RS20735
gene id: 1441930:Z042_RS20735
uniprot id: W0LGW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1441930:Z042 RS06855
gene id: 1441930:Z042_RS06855
uniprot id: W0LBW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1441930:Z042 RS12765
gene id: 1441930:Z042_RS12765
uniprot id: W0L4I8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

1441930:Z042 RS00850
gene id: 1441930:Z042_RS00850
uniprot id: W0LEV3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1441930:Z042 RS14520
gene id: 1441930:Z042_RS14520
uniprot id: W0L3U1
names: Similarity
messages: Belongs to the UPF0162 family.

1441930:Z042 RS11585
gene id: 1441930:Z042_RS11585
uniprot id: W0L960
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS22370
gene id: 1441930:Z042_RS22370
uniprot id: W0LH93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1441930:Z042 RS17990
gene id: 1441930:Z042_RS17990
uniprot id: W0LE60
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1441930:Z042 RS20645
gene id: 1441930:Z042_RS20645
uniprot id: W0LI03
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1441930:Z042 RS21935
gene id: 1441930:Z042_RS21935
uniprot id: W0LHI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS02260
gene id: 1441930:Z042_RS02260
uniprot id: W0LDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Glutamate:GABA antiporter (GGA) (TC 2.A.3.7) family.
messages: Membrane

1441930:Z042 RS21775
gene id: 1441930:Z042_RS21775
uniprot id: W0LC69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

1441930:Z042 RS21460
gene id: 1441930:Z042_RS21460
uniprot id: W0LGV0
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS23025
gene id: 1441930:Z042_RS23025
uniprot id: W0LGX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1441930:Z042 RS15850
gene id: 1441930:Z042_RS15850
uniprot id: W0LJK4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1441930:Z042 RS05210
gene id: 1441930:Z042_RS05210
uniprot id: W0LDM1
names: Subcellular Location Annotation
messages: Cytoplasm

1441930:Z042 RS01605
gene id: 1441930:Z042_RS01605
uniprot id: W0LE73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

1441930:Z042 RS06070
gene id: 1441930:Z042_RS06070
uniprot id: W0LBZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1441930:Z042 RS22965
gene id: 1441930:Z042_RS22965
uniprot id: W0LBV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS18800
gene id: 1441930:Z042_RS18800
uniprot id: W0LHS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

1441930:Z042 RS08765
gene id: 1441930:Z042_RS08765
uniprot id: W0L6K3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1441930:Z042 RS10945
gene id: 1441930:Z042_RS10945
uniprot id: W0L5M6
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1441930:Z042 RS16545
gene id: 1441930:Z042_RS16545
uniprot id: W0LK97
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

1441930:Z042 RS24345
gene id: 1441930:Z042_RS24345
uniprot id: W0LFC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS23190
gene id: 1441930:Z042_RS23190
uniprot id: W0LBF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1441930:Z042 RS00395
gene id: 1441930:Z042_RS00395
uniprot id: W0LLH1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1441930:Z042 RS16880
gene id: 1441930:Z042_RS16880
uniprot id: A0A0D4ZYK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS18145
gene id: 1441930:Z042_RS18145
uniprot id: W0LE33
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS15445
gene id: 1441930:Z042_RS15445
uniprot id: W0L8B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS06390
gene id: 1441930:Z042_RS06390
uniprot id: W0LBS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1441930:Z042 RS18525
gene id: 1441930:Z042_RS18525
uniprot id: W0LHX0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1441930:Z042 RS22880
gene id: 1441930:Z042_RS22880
uniprot id: W0LBL6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1441930:Z042 RS12105
gene id: 1441930:Z042_RS12105
uniprot id: W0L948
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1441930:Z042 RS19035
gene id: 1441930:Z042_RS19035
uniprot id: W0LIX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1441930:Z042 RS06845
gene id: 1441930:Z042_RS06845
uniprot id: W0LBJ6
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS09700
gene id: 1441930:Z042_RS09700
uniprot id: W0LAD9
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1441930:Z042 RS15415
gene id: 1441930:Z042_RS15415
uniprot id: W0L8B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1441930:Z042 RS24350
gene id: 1441930:Z042_RS24350
uniprot id: W0LB87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS03260
gene id: 1441930:Z042_RS03260
uniprot id: W0L9L5
names: Function
messages: Required for maximal bacterial cellulose synthesis.

1441930:Z042 RS11180
gene id: 1441930:Z042_RS11180
uniprot id: W0L9M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1441930:Z042 RS04965
gene id: 1441930:Z042_RS04965
uniprot id: W0LCH0
names: Similarity
messages: Belongs to the GARS family.

1441930:Z042 RS01175
gene id: 1441930:Z042_RS01175
uniprot id: W0LEE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1441930:Z042 RS06595
gene id: 1441930:Z042_RS06595
uniprot id: W0LBN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1441930:Z042 RS11265
gene id: 1441930:Z042_RS11265
uniprot id: A0A0D4ZYH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1441930:Z042 RS10530
gene id: 1441930:Z042_RS10530
uniprot id: W0LAS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

1441930:Z042 RS22900
gene id: 1441930:Z042_RS22900
uniprot id: W0LFS0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1441930:Z042 RS23510
gene id: 1441930:Z042_RS23510
uniprot id: W0LFE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1441930:Z042 RS10075
gene id: 1441930:Z042_RS10075
uniprot id: W0LB12
names: Similarity
messages: Belongs to the thioredoxin family.

1441930:Z042 RS17200
gene id: 1441930:Z042_RS17200
uniprot id: W0LJU3
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1441930:Z042 RS19385
gene id: 1441930:Z042_RS19385
uniprot id: W0LHK3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1441930:Z042 RS14850
gene id: 1441930:Z042_RS14850
uniprot id: W0L8N7
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

1441930:Z042 RS09750
gene id: 1441930:Z042_RS09750
uniprot id: W0LB79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS11020
gene id: 1441930:Z042_RS11020
uniprot id: W0L5L3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB.

1441930:Z042 RS05530
gene id: 1441930:Z042_RS05530
uniprot id: W0LC90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1441930:Z042 RS19410
gene id: 1441930:Z042_RS19410
uniprot id: W0LHJ8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1441930:Z042 RS21025
gene id: 1441930:Z042_RS21025
uniprot id: W0LGQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1441930:Z042 RS11115
gene id: 1441930:Z042_RS11115
uniprot id: W0L9N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1441930:Z042 RS01410
gene id: 1441930:Z042_RS01410
uniprot id: W0LFJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1441930:Z042 RS11715
gene id: 1441930:Z042_RS11715
uniprot id: W0L599
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1441930:Z042 RS02665
gene id: 1441930:Z042_RS02665
uniprot id: W0LEZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS09600
gene id: 1441930:Z042_RS09600
uniprot id: W0LAF6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS22420
gene id: 1441930:Z042_RS22420
uniprot id: W0LH88
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1441930:Z042 RS08555
gene id: 1441930:Z042_RS08555
uniprot id: W0LB15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1441930:Z042 RS15280
gene id: 1441930:Z042_RS15280
uniprot id: W0L7B6
names: Similarity
messages: Belongs to the UPF0263 family.

1441930:Z042 RS22220
gene id: 1441930:Z042_RS22220
uniprot id: W0LG43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1441930:Z042 RS03995
gene id: 1441930:Z042_RS03995
uniprot id: W0LDA9
names: Similarity
messages: Belongs to the CcdB toxin family.

1441930:Z042 RS14375
gene id: 1441930:Z042_RS14375
uniprot id: W0L3V9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1441930:Z042 RS05805
gene id: 1441930:Z042_RS05805
uniprot id: W0LCI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1441930:Z042 RS17370
gene id: 1441930:Z042_RS17370
uniprot id: W0LEE2
names: Similarity
messages: Belongs to the fabD family.

1441930:Z042 RS20010
gene id: 1441930:Z042_RS20010
uniprot id: W0LH95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1441930:Z042 RS18250
gene id: 1441930:Z042_RS18250
uniprot id: W0LI15
names: Similarity
messages: Belongs to the PhoH family.

1441930:Z042 RS17390
gene id: 1441930:Z042_RS17390
uniprot id: W0LIE6
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1441930:Z042 RS22885
gene id: 1441930:Z042_RS22885
uniprot id: W0LG24
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS09945
gene id: 1441930:Z042_RS09945
uniprot id: W0L639
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1441930:Z042 RS10735
gene id: 1441930:Z042_RS10735
uniprot id: W0L9I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

1441930:Z042 RS14710
gene id: 1441930:Z042_RS14710
uniprot id: W0L8T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS06470
gene id: 1441930:Z042_RS06470
uniprot id: W0L7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1441930:Z042 RS20330
gene id: 1441930:Z042_RS20330
uniprot id: W0LH40
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS09125
gene id: 1441930:Z042_RS09125
uniprot id: W0LBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
messages: Membrane

1441930:Z042 RS22110
gene id: 1441930:Z042_RS22110
uniprot id: W0LCC4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family. AroL subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The LID domain closes over the active site upon ATP binding.

1441930:Z042 RS02615
gene id: 1441930:Z042_RS02615
uniprot id: W0LEZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1441930:Z042 RS16650
gene id: 1441930:Z042_RS16650
uniprot id: W0LK65
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thioesterase PaaI family.
messages: Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS15695
gene id: 1441930:Z042_RS15695
uniprot id: W0LJM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1441930:Z042 RS01610
gene id: 1441930:Z042_RS01610
uniprot id: W0LA33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS03530
gene id: 1441930:Z042_RS03530
uniprot id: W0LD87
names: Similarity
messages: Belongs to the PhzF family.

1441930:Z042 RS08625
gene id: 1441930:Z042_RS08625
uniprot id: W0L6M3
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS05615
gene id: 1441930:Z042_RS05615
uniprot id: W0L851
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

1441930:Z042 RS22065
gene id: 1441930:Z042_RS22065
uniprot id: W0LHG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS10030
gene id: 1441930:Z042_RS10030
uniprot id: W0L9W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1441930:Z042 RS12240
gene id: 1441930:Z042_RS12240
uniprot id: W0L4S9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1441930:Z042 RS03925
gene id: 1441930:Z042_RS03925
uniprot id: A0A0D4ZYE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1441930:Z042 RS09040
gene id: 1441930:Z042_RS09040
uniprot id: W0L6M8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1441930:Z042 RS09880
gene id: 1441930:Z042_RS09880
uniprot id: W0L9Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1441930:Z042 RS08600
gene id: 1441930:Z042_RS08600
uniprot id: W0L6M6
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1441930:Z042 RS05790
gene id: 1441930:Z042_RS05790
uniprot id: W0LDD1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

1441930:Z042 RS10555
gene id: 1441930:Z042_RS10555
uniprot id: W0LAS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1441930:Z042 RS09000
gene id: 1441930:Z042_RS09000
uniprot id: W0L6H0
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS04650
gene id: 1441930:Z042_RS04650
uniprot id: W0L8K9
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS20755
gene id: 1441930:Z042_RS20755
uniprot id: W0LHY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

1441930:Z042 RS18840
gene id: 1441930:Z042_RS18840
uniprot id: W0LE26
names: Subcellular Location Annotation
messages: Cytoplasm

1441930:Z042 RS06055
gene id: 1441930:Z042_RS06055
uniprot id: W0LCD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1441930:Z042 RS05810
gene id: 1441930:Z042_RS05810
uniprot id: W0L8A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS16385
gene id: 1441930:Z042_RS16385
uniprot id: W0LFB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1441930:Z042 RS18890
gene id: 1441930:Z042_RS18890
uniprot id: W0LDP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1441930:Z042 RS09580
gene id: 1441930:Z042_RS09580
uniprot id: W0LL01
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1441930:Z042 RS20685
gene id: 1441930:Z042_RS20685
uniprot id: W0LHZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1441930:Z042 RS10105
gene id: 1441930:Z042_RS10105
uniprot id: W0L9V0
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS17070
gene id: 1441930:Z042_RS17070
uniprot id: W0LEJ1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1441930:Z042 RS09490
gene id: 1441930:Z042_RS09490
uniprot id: W0L647
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS21275
gene id: 1441930:Z042_RS21275
uniprot id: W0LGX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1441930:Z042 RS22630
gene id: 1441930:Z042_RS22630
uniprot id: W0LG69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1441930:Z042 RS17350
gene id: 1441930:Z042_RS17350
uniprot id: W0LIQ8
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1441930:Z042 RS10005
gene id: 1441930:Z042_RS10005
uniprot id: W0L9W6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1441930:Z042 RS12265
gene id: 1441930:Z042_RS12265
uniprot id: W0L4S4
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS09905
gene id: 1441930:Z042_RS09905
uniprot id: W0L9Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1441930:Z042 RS16685
gene id: 1441930:Z042_RS16685
uniprot id: W0LIT8
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1441930:Z042 RS08170
gene id: 1441930:Z042_RS08170
uniprot id: A0A0D4ZY24
names: Similarity
messages: Belongs to the autoinducer synthase family.

1441930:Z042 RS22465
gene id: 1441930:Z042_RS22465
uniprot id: W0LH78
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1441930:Z042 RS13115
gene id: 1441930:Z042_RS13115
uniprot id: W0L9E3
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1441930:Z042 RS23115
gene id: 1441930:Z042_RS23115
uniprot id: W0LFM6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS17290
gene id: 1441930:Z042_RS17290
uniprot id: W0LIG9
names: Similarity
messages: Belongs to the UPF0227 family.

1441930:Z042 RS15285
gene id: 1441930:Z042_RS15285
uniprot id: W0L3D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS24155
gene id: 1441930:Z042_RS24155
uniprot id: W0LAY8
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

1441930:Z042 RS07035
gene id: 1441930:Z042_RS07035
uniprot id: W0L7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS15870
gene id: 1441930:Z042_RS15870
uniprot id: W0LF62
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1441930:Z042 RS04120
gene id: 1441930:Z042_RS04120
uniprot id: W0LCY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1441930:Z042 RS13905
gene id: 1441930:Z042_RS13905
uniprot id: W0L8C7
names: Similarity
messages: Belongs to the peptidase A31 family.

1441930:Z042 RS15930
gene id: 1441930:Z042_RS15930
uniprot id: W0LJJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1441930:Z042 RS01115
gene id: 1441930:Z042_RS01115
uniprot id: W0LAK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1441930:Z042 RS22410
gene id: 1441930:Z042_RS22410
uniprot id: W0LGA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1441930:Z042 RS07420
gene id: 1441930:Z042_RS07420
uniprot id: W0LB86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1441930:Z042 RS16380
gene id: 1441930:Z042_RS16380
uniprot id: W0LJB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1441930:Z042 RS11610
gene id: 1441930:Z042_RS11610
uniprot id: W0L5B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1441930:Z042 RS10990
gene id: 1441930:Z042_RS10990
uniprot id: W0L9Q8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

1441930:Z042 RS03180
gene id: 1441930:Z042_RS03180
uniprot id: W0LDR9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS04160
gene id: 1441930:Z042_RS04160
uniprot id: W0L916
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS19055
gene id: 1441930:Z042_RS19055
uniprot id: W0LDZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1441930:Z042 RS23390
gene id: 1441930:Z042_RS23390
uniprot id: W0LBB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1441930:Z042 RS14715
gene id: 1441930:Z042_RS14715
uniprot id: W0L7P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS11885
gene id: 1441930:Z042_RS11885
uniprot id: W0L545
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1441930:Z042 RS04085
gene id: 1441930:Z042_RS04085
uniprot id: W0LCZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1441930:Z042 RS06105
gene id: 1441930:Z042_RS06105
uniprot id: W0LCC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1441930:Z042 RS09405
gene id: 1441930:Z042_RS09405
uniprot id: W0LA75
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1441930:Z042 RS21675
gene id: 1441930:Z042_RS21675
uniprot id: W0LC86
names: Similarity
messages: Belongs to the P(II) protein family.

1441930:Z042 RS06900
gene id: 1441930:Z042_RS06900
uniprot id: W0L7F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

1441930:Z042 RS19465
gene id: 1441930:Z042_RS19465
uniprot id: W0LDP5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1441930:Z042 RS11450
gene id: 1441930:Z042_RS11450
uniprot id: W0L9H9
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS06220
gene id: 1441930:Z042_RS06220
uniprot id: W0LBY0
names: Cofactor
messages: Can also use Mn(2+) ion.

1441930:Z042 RS04455
gene id: 1441930:Z042_RS04455
uniprot id: W0L8X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1441930:Z042 RS04790
gene id: 1441930:Z042_RS04790
uniprot id: W0L8Q9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1441930:Z042 RS06560
gene id: 1441930:Z042_RS06560
uniprot id: W0L7T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1441930:Z042 RS23760
gene id: 1441930:Z042_RS23760
uniprot id: W0LFA2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1441930:Z042 RS10550
gene id: 1441930:Z042_RS10550
uniprot id: W0L5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1441930:Z042 RS03900
gene id: 1441930:Z042_RS03900
uniprot id: W0LEB0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1441930:Z042 RS21070
gene id: 1441930:Z042_RS21070
uniprot id: W0LCW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1441930:Z042 RS22635
gene id: 1441930:Z042_RS22635
uniprot id: W0LC04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.

1441930:Z042 RS09705
gene id: 1441930:Z042_RS09705
uniprot id: W0L680
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: Homohexamer.

1441930:Z042 RS02925
gene id: 1441930:Z042_RS02925
uniprot id: W0LFZ7
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1441930:Z042 RS10095
gene id: 1441930:Z042_RS10095
uniprot id: W0L617
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS19555
gene id: 1441930:Z042_RS19555
uniprot id: A0A0D4ZYJ5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1441930:Z042 RS06525
gene id: 1441930:Z042_RS06525
uniprot id: W0L7M4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1441930:Z042 RS06460
gene id: 1441930:Z042_RS06460
uniprot id: W0LCZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1441930:Z042 RS23615
gene id: 1441930:Z042_RS23615
uniprot id: W0LFC6
names: Similarity
messages: Belongs to the Smp family.

1441930:Z042 RS12865
gene id: 1441930:Z042_RS12865
uniprot id: W0L8F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS23610
gene id: 1441930:Z042_RS23610
uniprot id: W0LGK4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1441930:Z042 RS20145
gene id: 1441930:Z042_RS20145
uniprot id: W0LDB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS07490
gene id: 1441930:Z042_RS07490
uniprot id: W0L7C4
names: Similarity
messages: Belongs to the creatininase superfamily.

1441930:Z042 RS04415
gene id: 1441930:Z042_RS04415
uniprot id: W0LD38
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS09500
gene id: 1441930:Z042_RS09500
uniprot id: A0A0D4ZXH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1441930:Z042 RS05935
gene id: 1441930:Z042_RS05935
uniprot id: W0L883
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1441930:Z042 RS04110
gene id: 1441930:Z042_RS04110
uniprot id: W0L925
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS04200
gene id: 1441930:Z042_RS04200
uniprot id: W0L8T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1441930:Z042 RS20535
gene id: 1441930:Z042_RS20535
uniprot id: W0LD49
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1441930:Z042 RS10480
gene id: 1441930:Z042_RS10480
uniprot id: W0LAU0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1441930:Z042 RS06000
gene id: 1441930:Z042_RS06000
uniprot id: W0L7Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1441930:Z042 RS08510
gene id: 1441930:Z042_RS08510
uniprot id: W0LAQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

1441930:Z042 RS17325
gene id: 1441930:Z042_RS17325
uniprot id: W0LIR2
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS11500
gene id: 1441930:Z042_RS11500
uniprot id: W0L558
names: Subcellular Location Annotation
messages: Cytoplasm

1441930:Z042 RS11995
gene id: 1441930:Z042_RS11995
uniprot id: A0A0D4ZXR5
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1441930:Z042 RS11850
gene id: 1441930:Z042_RS11850
uniprot id: W0L502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS21820
gene id: 1441930:Z042_RS21820
uniprot id: W0LGD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS22960
gene id: 1441930:Z042_RS22960
uniprot id: W0LG13
names: Similarity
messages: Belongs to the GSP E family.

1441930:Z042 RS11310
gene id: 1441930:Z042_RS11310
uniprot id: W0LAE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1441930:Z042 RS10275
gene id: 1441930:Z042_RS10275
uniprot id: W0L5Y4
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS21125
gene id: 1441930:Z042_RS21125
uniprot id: W0LCV3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1441930:Z042 RS10165
gene id: 1441930:Z042_RS10165
uniprot id: W0LA56
names: Function
names: Similarity
messages: Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily.
messages: Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1-sulfonate (DHPS).

1441930:Z042 RS12250
gene id: 1441930:Z042_RS12250
uniprot id: W0L4Y5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedD family.
messages: Cell inner membrane
messages: Non-essential cell division protein that could be required for efficient cell constriction.
messages: The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.

1441930:Z042 RS15480
gene id: 1441930:Z042_RS15480
uniprot id: W0L399
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

1441930:Z042 RS12120
gene id: 1441930:Z042_RS12120
uniprot id: W0L8S7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1441930:Z042 RS22315
gene id: 1441930:Z042_RS22315
uniprot id: W0LHA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1441930:Z042 RS08640
gene id: 1441930:Z042_RS08640
uniprot id: W0LBV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1441930:Z042 RS06710
gene id: 1441930:Z042_RS06710
uniprot id: W0L7R4
names: Similarity
messages: Belongs to the peptidase U62 family.

1441930:Z042 RS06090
gene id: 1441930:Z042_RS06090
uniprot id: W0LD82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1441930:Z042 RS16645
gene id: 1441930:Z042_RS16645
uniprot id: W0LF58
names: Similarity
messages: Belongs to the HesB/IscA family.

1441930:Z042 RS14365
gene id: 1441930:Z042_RS14365
uniprot id: W0L8Z0
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

1441930:Z042 RS02050
gene id: 1441930:Z042_RS02050
uniprot id: W0L9W0
names: Similarity
messages: Belongs to the intimin/invasin family.

1441930:Z042 RS14700
gene id: 1441930:Z042_RS14700
uniprot id: W0L3X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS14395
gene id: 1441930:Z042_RS14395
uniprot id: W0L7T6
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS21650
gene id: 1441930:Z042_RS21650
uniprot id: W0LGR7
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

1441930:Z042 RS20630
gene id: 1441930:Z042_RS20630
uniprot id: W0LCS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS05855
gene id: 1441930:Z042_RS05855
uniprot id: W0LCH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

1441930:Z042 RS09800
gene id: 1441930:Z042_RS09800
uniprot id: W0LB68
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1441930:Z042 RS23145
gene id: 1441930:Z042_RS23145
uniprot id: W0LBG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS07885
gene id: 1441930:Z042_RS07885
uniprot id: W0LBC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1441930:Z042 RS10470
gene id: 1441930:Z042_RS10470
uniprot id: W0LA05
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1441930:Z042 RS20035
gene id: 1441930:Z042_RS20035
uniprot id: W0LD35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS10500
gene id: 1441930:Z042_RS10500
uniprot id: W0L5U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1441930:Z042 RS07815
gene id: 1441930:Z042_RS07815
uniprot id: W0L767
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1441930:Z042 RS04490
gene id: 1441930:Z042_RS04490
uniprot id: W0LCR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1441930:Z042 RS20560
gene id: 1441930:Z042_RS20560
uniprot id: W0LD44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1441930:Z042 RS15030
gene id: 1441930:Z042_RS15030
uniprot id: W0L8J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1441930:Z042 RS00200
gene id: 1441930:Z042_RS00200
uniprot id: W0LF78
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1441930:Z042 RS21825
gene id: 1441930:Z042_RS21825
uniprot id: W0LC63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1441930:Z042 RS21950
gene id: 1441930:Z042_RS21950
uniprot id: W0LGL7
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

1441930:Z042 RS17305
gene id: 1441930:Z042_RS17305
uniprot id: W0LES2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LpoB family.
messages: Cell outer membrane
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

1441930:Z042 RS12515
gene id: 1441930:Z042_RS12515
uniprot id: W0L8L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1441930:Z042 RS08850
gene id: 1441930:Z042_RS08850
uniprot id: W0LBS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1441930:Z042 RS06500
gene id: 1441930:Z042_RS06500
uniprot id: W0L7M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1441930:Z042 RS13625
gene id: 1441930:Z042_RS13625
uniprot id: W0L463
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1441930:Z042 RS16625
gene id: 1441930:Z042_RS16625
uniprot id: W0LK83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
messages: Cytoplasm
messages: Homodimer. Interacts with SufE and the SufBCD complex composed of SufB, SufC and SufD. The interaction with SufE is required to mediate the direct transfer of the sulfur atom from the S-sulfanylcysteine.

1441930:Z042 RS03320
gene id: 1441930:Z042_RS03320
uniprot id: W0LEN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS01095
gene id: 1441930:Z042_RS01095
uniprot id: W0LFQ4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1441930:Z042 RS04465
gene id: 1441930:Z042_RS04465
uniprot id: W0LCS3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS20350
gene id: 1441930:Z042_RS20350
uniprot id: W0LI61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

1441930:Z042 RS12035
gene id: 1441930:Z042_RS12035
uniprot id: W0L518
names: Similarity
messages: Belongs to the UPF0115 family.

1441930:Z042 RS04725
gene id: 1441930:Z042_RS04725
uniprot id: W0LCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1441930:Z042 RS21120
gene id: 1441930:Z042_RS21120
uniprot id: W0LH04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1441930:Z042 RS03815
gene id: 1441930:Z042_RS03815
uniprot id: W0LDE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1441930:Z042 RS00150
gene id: 1441930:Z042_RS00150
uniprot id: W0LF89
names: Similarity
messages: Belongs to the carbamate kinase family.

1441930:Z042 RS05795
gene id: 1441930:Z042_RS05795
uniprot id: W0LC48
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1441930:Z042 RS06425
gene id: 1441930:Z042_RS06425
uniprot id: W0LC46
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1441930:Z042 RS03715
gene id: 1441930:Z042_RS03715
uniprot id: W0L992
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers. Binds only one seryl-tRNA(Sec) per dimer.

1441930:Z042 RS16670
gene id: 1441930:Z042_RS16670
uniprot id: W0LJ49
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1441930:Z042 RS18230
gene id: 1441930:Z042_RS18230
uniprot id: W0LE16
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

1441930:Z042 RS05135
gene id: 1441930:Z042_RS05135
uniprot id: W0LCR9
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS20760
gene id: 1441930:Z042_RS20760
uniprot id: W0LGV8
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

1441930:Z042 RS18595
gene id: 1441930:Z042_RS18595
uniprot id: W0LJ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS13550
gene id: 1441930:Z042_RS13550
uniprot id: W0L8H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HspQ family.
messages: Cytoplasm
messages: Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.

1441930:Z042 RS09910
gene id: 1441930:Z042_RS09910
uniprot id: W0L5W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1441930:Z042 RS13025
gene id: 1441930:Z042_RS13025
uniprot id: W0L4E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1441930:Z042 RS12595
gene id: 1441930:Z042_RS12595
uniprot id: W0L4L8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1441930:Z042 RS22930
gene id: 1441930:Z042_RS22930
uniprot id: W0LBK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1441930:Z042 RS12535
gene id: 1441930:Z042_RS12535
uniprot id: W0L9P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

1441930:Z042 RS23285
gene id: 1441930:Z042_RS23285
uniprot id: W0LBQ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS11110
gene id: 1441930:Z042_RS11110
uniprot id: W0L5B6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1441930:Z042 RS08635
gene id: 1441930:Z042_RS08635
uniprot id: W0L6V1
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1441930:Z042 RS06465
gene id: 1441930:Z042_RS06465
uniprot id: W0LBR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1441930:Z042 RS12040
gene id: 1441930:Z042_RS12040
uniprot id: W0L9Y6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1441930:Z042 RS07370
gene id: 1441930:Z042_RS07370
uniprot id: W0LB96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1441930:Z042 RS18935
gene id: 1441930:Z042_RS18935
uniprot id: W0LIZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1441930:Z042 RS23645
gene id: 1441930:Z042_RS23645
uniprot id: W0LFC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1441930:Z042 RS09085
gene id: 1441930:Z042_RS09085
uniprot id: W0L6E1
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS13925
gene id: 1441930:Z042_RS13925
uniprot id: W0L424
names: Similarity
messages: Belongs to the HupF/HypC family.

1441930:Z042 RS02550
gene id: 1441930:Z042_RS02550
uniprot id: W0LF03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1441930:Z042 RS00555
gene id: 1441930:Z042_RS00555
uniprot id: W0LG19
names: Similarity
messages: Belongs to the EcpB/EcpE family.

1441930:Z042 RS19300
gene id: 1441930:Z042_RS19300
uniprot id: W0LHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS16415
gene id: 1441930:Z042_RS16415
uniprot id: W0LKB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1441930:Z042 RS15150
gene id: 1441930:Z042_RS15150
uniprot id: W0L8G9
names: Similarity
messages: Belongs to the asparaginase 1 family.

1441930:Z042 RS07055
gene id: 1441930:Z042_RS07055
uniprot id: W0LBF6
names: Similarity
messages: Belongs to the UxaA family.

1441930:Z042 RS16820
gene id: 1441930:Z042_RS16820
uniprot id: W0LIR1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1441930:Z042 RS07715
gene id: 1441930:Z042_RS07715
uniprot id: W0L784
names: Similarity
messages: Belongs to the UPF0441 family.

1441930:Z042 RS04705
gene id: 1441930:Z042_RS04705
uniprot id: W0L8J7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1441930:Z042 RS18565
gene id: 1441930:Z042_RS18565
uniprot id: W0LE71
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

1441930:Z042 RS14315
gene id: 1441930:Z042_RS14315
uniprot id: W0L434
names: Similarity
messages: Belongs to the peptidase C40 family.

1441930:Z042 RS17925
gene id: 1441930:Z042_RS17925
uniprot id: W0LI74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1441930:Z042 RS09695
gene id: 1441930:Z042_RS09695
uniprot id: W0L608
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1441930:Z042 RS18020
gene id: 1441930:Z042_RS18020
uniprot id: W0LIF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS21980
gene id: 1441930:Z042_RS21980
uniprot id: W0LCF5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1441930:Z042 RS21750
gene id: 1441930:Z042_RS21750
uniprot id: W0LC73
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1441930:Z042 RS04215
gene id: 1441930:Z042_RS04215
uniprot id: W0LE35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS19580
gene id: 1441930:Z042_RS19580
uniprot id: W0LIM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1441930:Z042 RS02015
gene id: 1441930:Z042_RS02015
uniprot id: W0L9W5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1441930:Z042 RS23635
gene id: 1441930:Z042_RS23635
uniprot id: W0LBJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

1441930:Z042 RS21765
gene id: 1441930:Z042_RS21765
uniprot id: W0LHK0
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS11305
gene id: 1441930:Z042_RS11305
uniprot id: W0L5G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudK subfamily.
messages: Homodimer.
messages: Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.

1441930:Z042 RS22650
gene id: 1441930:Z042_RS22650
uniprot id: W0LBQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

1441930:Z042 RS15890
gene id: 1441930:Z042_RS15890
uniprot id: W0LJA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS06885
gene id: 1441930:Z042_RS06885
uniprot id: W0L7N1
names: Similarity
messages: Belongs to the peptidase S1C family.

1441930:Z042 RS01565
gene id: 1441930:Z042_RS01565
uniprot id: W0LEI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1441930:Z042 RS16710
gene id: 1441930:Z042_RS16710
uniprot id: W0LIT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnE family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

1441930:Z042 RS18320
gene id: 1441930:Z042_RS18320
uniprot id: W0LJA2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1441930:Z042 RS12680
gene id: 1441930:Z042_RS12680
uniprot id: W0L8I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS08500
gene id: 1441930:Z042_RS08500
uniprot id: W0L6X1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1441930:Z042 RS10740
gene id: 1441930:Z042_RS10740
uniprot id: W0L5H8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1441930:Z042 RS14000
gene id: 1441930:Z042_RS14000
uniprot id: W0L410
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS01600
gene id: 1441930:Z042_RS01600
uniprot id: W0LFG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

1441930:Z042 RS19395
gene id: 1441930:Z042_RS19395
uniprot id: W0LHS5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1441930:Z042 RS16295
gene id: 1441930:Z042_RS16295
uniprot id: W0LKD4
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS06505
gene id: 1441930:Z042_RS06505
uniprot id: W0LC29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1441930:Z042 RS16900
gene id: 1441930:Z042_RS16900
uniprot id: W0LIP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1441930:Z042 RS04565
gene id: 1441930:Z042_RS04565
uniprot id: W0LCQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1441930:Z042 RS22645
gene id: 1441930:Z042_RS22645
uniprot id: W0LFW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1441930:Z042 RS12605
gene id: 1441930:Z042_RS12605
uniprot id: W0L4R7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

1441930:Z042 RS09805
gene id: 1441930:Z042_RS09805
uniprot id: W0LA09
names: Similarity
messages: Belongs to the peptidase S33 family.

1441930:Z042 RS19620
gene id: 1441930:Z042_RS19620
uniprot id: W0LDB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1441930:Z042 RS06825
gene id: 1441930:Z042_RS06825
uniprot id: W0L7H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1441930:Z042 RS18385
gene id: 1441930:Z042_RS18385
uniprot id: W0LI87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

1441930:Z042 RS07595
gene id: 1441930:Z042_RS07595
uniprot id: W0L7A5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1441930:Z042 RS20775
gene id: 1441930:Z042_RS20775
uniprot id: W0LD12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

1441930:Z042 RS07870
gene id: 1441930:Z042_RS07870
uniprot id: W0LC77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS16915
gene id: 1441930:Z042_RS16915
uniprot id: W0LEZ5
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS11075
gene id: 1441930:Z042_RS11075
uniprot id: W0LAI5
names: Similarity
messages: Belongs to the GppA/Ppx family.

1441930:Z042 RS09655
gene id: 1441930:Z042_RS09655
uniprot id: W0L690
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1441930:Z042 RS18755
gene id: 1441930:Z042_RS18755
uniprot id: W0LDR4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1441930:Z042 RS06160
gene id: 1441930:Z042_RS06160
uniprot id: W0L842
names: Similarity
messages: Belongs to the Smg family.

1441930:Z042 RS23840
gene id: 1441930:Z042_RS23840
uniprot id: W0LGH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

1441930:Z042 RS04320
gene id: 1441930:Z042_RS04320
uniprot id: W0LE20
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1441930:Z042 RS02310
gene id: 1441930:Z042_RS02310
uniprot id: W0LF47
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS13060
gene id: 1441930:Z042_RS13060
uniprot id: W0L9F1
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1441930:Z042 RS14925
gene id: 1441930:Z042_RS14925
uniprot id: W0L8L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1441930:Z042 RS09670
gene id: 1441930:Z042_RS09670
uniprot id: W0L614
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS08735
gene id: 1441930:Z042_RS08735
uniprot id: W0L6K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS05485
gene id: 1441930:Z042_RS05485
uniprot id: W0LCM2
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.

1441930:Z042 RS01235
gene id: 1441930:Z042_RS01235
uniprot id: W0LEN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1441930:Z042 RS07185
gene id: 1441930:Z042_RS07185
uniprot id: W0LCK6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS14920
gene id: 1441930:Z042_RS14920
uniprot id: W0L3Q2
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1441930:Z042 RS15035
gene id: 1441930:Z042_RS15035
uniprot id: W0L7F9
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1441930:Z042 RS17265
gene id: 1441930:Z042_RS17265
uniprot id: W0LIH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1441930:Z042 RS23170
gene id: 1441930:Z042_RS23170
uniprot id: W0LFX5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1441930:Z042 RS18750
gene id: 1441930:Z042_RS18750
uniprot id: W0LHT2
names: Similarity
messages: Belongs to the peptidase M1 family.

1441930:Z042 RS06600
gene id: 1441930:Z042_RS06600
uniprot id: W0L7L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1441930:Z042 RS17665
gene id: 1441930:Z042_RS17665
uniprot id: W0LIK5
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1441930:Z042 RS04365
gene id: 1441930:Z042_RS04365
uniprot id: W0L8Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1441930:Z042 RS07385
gene id: 1441930:Z042_RS07385
uniprot id: W0L7E3
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1441930:Z042 RS23445
gene id: 1441930:Z042_RS23445
uniprot id: W0LFS4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

1441930:Z042 RS16995
gene id: 1441930:Z042_RS16995
uniprot id: W0LEK4
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS10560
gene id: 1441930:Z042_RS10560
uniprot id: W0L9L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS23935
gene id: 1441930:Z042_RS23935
uniprot id: W0LB20
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS03795
gene id: 1441930:Z042_RS03795
uniprot id: W0L980
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

1441930:Z042 RS06140
gene id: 1441930:Z042_RS06140
uniprot id: W0LD72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1441930:Z042 RS23010
gene id: 1441930:Z042_RS23010
uniprot id: W0LBJ1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1441930:Z042 RS16775
gene id: 1441930:Z042_RS16775
uniprot id: W0LEP3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

1441930:Z042 RS23490
gene id: 1441930:Z042_RS23490
uniprot id: W0LB98
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1441930:Z042 RS12015
gene id: 1441930:Z042_RS12015
uniprot id: W0L9Z3
names: Similarity
messages: Belongs to the UPF0381 family.

1441930:Z042 RS12440
gene id: 1441930:Z042_RS12440
uniprot id: W0L8M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS12850
gene id: 1441930:Z042_RS12850
uniprot id: W0L8S5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1441930:Z042 RS16485
gene id: 1441930:Z042_RS16485
uniprot id: W0LFA0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1441930:Z042 RS13920
gene id: 1441930:Z042_RS13920
uniprot id: W0L7Z7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1441930:Z042 RS21915
gene id: 1441930:Z042_RS21915
uniprot id: W0LKI5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS20850
gene id: 1441930:Z042_RS20850
uniprot id: W0LCZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1441930:Z042 RS04345
gene id: 1441930:Z042_RS04345
uniprot id: W0LE15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS02630
gene id: 1441930:Z042_RS02630
uniprot id: W0LE12
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

1441930:Z042 RS01080
gene id: 1441930:Z042_RS01080
uniprot id: W0LAB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1441930:Z042 RS02580
gene id: 1441930:Z042_RS02580
uniprot id: W0L9M2
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

1441930:Z042 RS23720
gene id: 1441930:Z042_RS23720
uniprot id: W0LFM7
names: Function
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.
messages: Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH. Subsequently, the reduced flavins diffuse to the large HpaB component or to other electron acceptors such as cytochrome c and Fe(3+) ion.

1441930:Z042 RS18925
gene id: 1441930:Z042_RS18925
uniprot id: W0LHZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1441930:Z042 RS12450
gene id: 1441930:Z042_RS12450
uniprot id: W0L8Z9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS21730
gene id: 1441930:Z042_RS21730
uniprot id: W0LGQ3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1441930:Z042 RS13485
gene id: 1441930:Z042_RS13485
uniprot id: W0L9A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtfA family.
messages: Cytoplasm
messages: Interacts with Mlc.
messages: Involved in the regulation of ptsG expression by binding and inactivating Mlc.

1441930:Z042 RS19010
gene id: 1441930:Z042_RS19010
uniprot id: W0LIY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1441930:Z042 RS11480
gene id: 1441930:Z042_RS11480
uniprot id: W0L9H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS18940
gene id: 1441930:Z042_RS18940
uniprot id: W0LHQ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1441930:Z042 RS07360
gene id: 1441930:Z042_RS07360
uniprot id: W0L7E8
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1441930:Z042 RS24385
gene id: 1441930:Z042_RS24385
uniprot id: W0LG88
names: Similarity
messages: Belongs to the RutC family.

1441930:Z042 RS12995
gene id: 1441930:Z042_RS12995
uniprot id: W0L4E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS02965
gene id: 1441930:Z042_RS02965
uniprot id: W0LDV1
names: Similarity
messages: Belongs to the carbamate kinase family.

1441930:Z042 RS05585
gene id: 1441930:Z042_RS05585
uniprot id: W0LC83
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1441930:Z042 RS11385
gene id: 1441930:Z042_RS11385
uniprot id: W0LAD7
names: Similarity
messages: Belongs to the UPF0178 family.

1441930:Z042 RS07290
gene id: 1441930:Z042_RS07290
uniprot id: W0LBB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1441930:Z042 RS19120
gene id: 1441930:Z042_RS19120
uniprot id: W0LHN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1441930:Z042 RS10545
gene id: 1441930:Z042_RS10545
uniprot id: W0L9Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1441930:Z042 RS14930
gene id: 1441930:Z042_RS14930
uniprot id: W0L7I0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1441930:Z042 RS22450
gene id: 1441930:Z042_RS22450
uniprot id: W0LG01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

1441930:Z042 RS14500
gene id: 1441930:Z042_RS14500
uniprot id: W0L836
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1441930:Z042 RS03920
gene id: 1441930:Z042_RS03920
uniprot id: W0L958
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1441930:Z042 RS00490
gene id: 1441930:Z042_RS00490
uniprot id: W0LAZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1441930:Z042 RS17470
gene id: 1441930:Z042_RS17470
uniprot id: W0LEC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1441930:Z042 RS17375
gene id: 1441930:Z042_RS17375
uniprot id: W0LIQ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1441930:Z042 RS03875
gene id: 1441930:Z042_RS03875
uniprot id: W0LEB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

1441930:Z042 RS02525
gene id: 1441930:Z042_RS02525
uniprot id: W0LF08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1441930:Z042 RS06910
gene id: 1441930:Z042_RS06910
uniprot id: W0L7M5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1441930:Z042 RS21900
gene id: 1441930:Z042_RS21900
uniprot id: W0LC52
names: Function
names: Similarity
messages: Belongs to the AcpH family.
messages: Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.

1441930:Z042 RS11145
gene id: 1441930:Z042_RS11145
uniprot id: W0L9C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaA family. HdA subfamily.
messages: Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA.
messages: Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.
messages: The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).

1441930:Z042 RS22225
gene id: 1441930:Z042_RS22225
uniprot id: W0LBX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1441930:Z042 RS07295
gene id: 1441930:Z042_RS07295
uniprot id: W0L789
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1441930:Z042 RS09665
gene id: 1441930:Z042_RS09665
uniprot id: W0LA35
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS03265
gene id: 1441930:Z042_RS03265
uniprot id: A0A0D4ZYA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

1441930:Z042 RS03215
gene id: 1441930:Z042_RS03215
uniprot id: W0LEQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1441930:Z042 RS01170
gene id: 1441930:Z042_RS01170
uniprot id: W0LFN9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1441930:Z042 RS16455
gene id: 1441930:Z042_RS16455
uniprot id: W0LJA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1441930:Z042 RS06380
gene id: 1441930:Z042_RS06380
uniprot id: W0L7X9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1441930:Z042 RS07460
gene id: 1441930:Z042_RS07460
uniprot id: W0L7C9
names: Similarity
messages: Belongs to the type III secretion exporter family.

1441930:Z042 RS07840
gene id: 1441930:Z042_RS07840
uniprot id: W0L763
names: Subunit
messages: Monomer.

1441930:Z042 RS15660
gene id: 1441930:Z042_RS15660
uniprot id: W0LJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS04335
gene id: 1441930:Z042_RS04335
uniprot id: W0LD50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS18005
gene id: 1441930:Z042_RS18005
uniprot id: W0LJF8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1441930:Z042 RS23430
gene id: 1441930:Z042_RS23430
uniprot id: W0LGP3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1441930:Z042 RS02705
gene id: 1441930:Z042_RS02705
uniprot id: W0LDZ7
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1441930:Z042 RS02215
gene id: 1441930:Z042_RS02215
uniprot id: W0LE83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1441930:Z042 RS03355
gene id: 1441930:Z042_RS03355
uniprot id: W0LDD7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1441930:Z042 RS03210
gene id: 1441930:Z042_RS03210
uniprot id: W0L9M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS23985
gene id: 1441930:Z042_RS23985
uniprot id: W0LGE8
names: Similarity
messages: Belongs to the CdaR family.

1441930:Z042 RS08940
gene id: 1441930:Z042_RS08940
uniprot id: W0L6H8
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

1441930:Z042 RS18905
gene id: 1441930:Z042_RS18905
uniprot id: W0LJ03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS04445
gene id: 1441930:Z042_RS04445
uniprot id: W0L8P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1441930:Z042 RS00960
gene id: 1441930:Z042_RS00960
uniprot id: W0LET2
names: Similarity
messages: Belongs to the peptidase S13 family.

1441930:Z042 RS23175
gene id: 1441930:Z042_RS23175
uniprot id: W0LBS0
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

1441930:Z042 RS24025
gene id: 1441930:Z042_RS24025
uniprot id: W0LB06
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1441930:Z042 RS06420
gene id: 1441930:Z042_RS06420
uniprot id: W0L7P4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1441930:Z042 RS16715
gene id: 1441930:Z042_RS16715
uniprot id: W0LEQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1441930:Z042 RS18490
gene id: 1441930:Z042_RS18490
uniprot id: W0LE86
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1441930:Z042 RS02845
gene id: 1441930:Z042_RS02845
uniprot id: W0LDK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1441930:Z042 RS06010
gene id: 1441930:Z042_RS06010
uniprot id: W0L868
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1441930:Z042 RS17875
gene id: 1441930:Z042_RS17875
uniprot id: W0LI84
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1441930:Z042 RS16585
gene id: 1441930:Z042_RS16585
uniprot id: W0LF83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.

1441930:Z042 RS21160
gene id: 1441930:Z042_RS21160
uniprot id: W0LGN1
names: Subcellular Location Annotation
messages: Cytoplasm

1441930:Z042 RS06145
gene id: 1441930:Z042_RS06145
uniprot id: W0LBY7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1441930:Z042 RS02540
gene id: 1441930:Z042_RS02540
uniprot id: W0LE24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

1441930:Z042 RS21680
gene id: 1441930:Z042_RS21680
uniprot id: W0LGR2
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS10595
gene id: 1441930:Z042_RS10595
uniprot id: W0L9Y3
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1441930:Z042 RS04925
gene id: 1441930:Z042_RS04925
uniprot id: W0LCV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Membrane
messages: Transports acetate.

1441930:Z042 RS05580
gene id: 1441930:Z042_RS05580
uniprot id: W0LDG1
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

1441930:Z042 RS04385
gene id: 1441930:Z042_RS04385
uniprot id: W0L8Q5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1441930:Z042 RS12475
gene id: 1441930:Z042_RS12475
uniprot id: W0L8Z2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1441930:Z042 RS18700
gene id: 1441930:Z042_RS18700
uniprot id: W0LHU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1441930:Z042 RS11620
gene id: 1441930:Z042_RS11620
uniprot id: W0L956
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
messages: Cell inner membrane
messages: Component of an export pathway for enterobactin.
messages: Membrane

1441930:Z042 RS23040
gene id: 1441930:Z042_RS23040
uniprot id: W0LBI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1441930:Z042 RS22175
gene id: 1441930:Z042_RS22175
uniprot id: W0LC09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1441930:Z042 RS02335
gene id: 1441930:Z042_RS02335
uniprot id: W0LF43
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family. AlsE subfamily.
messages: Catalyzes the reversible epimerization of D-allulose 6-phosphate to D-fructose 6-phosphate. Can also catalyze with lower efficiency the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1441930:Z042 RS23055
gene id: 1441930:Z042_RS23055
uniprot id: W0LGW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS08605
gene id: 1441930:Z042_RS08605
uniprot id: W0LB05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1441930:Z042 RS15875
gene id: 1441930:Z042_RS15875
uniprot id: W0LJK0
names: Similarity
messages: Belongs to the AHA1 family.

1441930:Z042 RS03865
gene id: 1441930:Z042_RS03865
uniprot id: W0LDD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
messages: Cell membrane

1441930:Z042 RS10510
gene id: 1441930:Z042_RS10510
uniprot id: W0L9M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

1441930:Z042 RS06215
gene id: 1441930:Z042_RS06215
uniprot id: W0LD63
names: Similarity
messages: Belongs to the malate synthase family.

1441930:Z042 RS10015
gene id: 1441930:Z042_RS10015
uniprot id: W0LA78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1441930:Z042 RS06305
gene id: 1441930:Z042_RS06305
uniprot id: W0L7U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1441930:Z042 RS13875
gene id: 1441930:Z042_RS13875
uniprot id: W0L432
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS08580
gene id: 1441930:Z042_RS08580
uniprot id: W0LB10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Monomer.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1441930:Z042 RS21860
gene id: 1441930:Z042_RS21860
uniprot id: W0LCH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1441930:Z042 RS10770
gene id: 1441930:Z042_RS10770
uniprot id: W0L9U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

1441930:Z042 RS06255
gene id: 1441930:Z042_RS06255
uniprot id: W0LCA4
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS23805
gene id: 1441930:Z042_RS23805
uniprot id: W0LGH4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1441930:Z042 RS00875
gene id: 1441930:Z042_RS00875
uniprot id: W0LEU8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

1441930:Z042 RS16955
gene id: 1441930:Z042_RS16955
uniprot id: W0LEK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

1441930:Z042 RS19700
gene id: 1441930:Z042_RS19700
uniprot id: W0LHK2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS04960
gene id: 1441930:Z042_RS04960
uniprot id: W0LDQ8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1441930:Z042 RS15165
gene id: 1441930:Z042_RS15165
uniprot id: W0L7R0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1441930:Z042 RS00970
gene id: 1441930:Z042_RS00970
uniprot id: W0LFS9
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS20705
gene id: 1441930:Z042_RS20705
uniprot id: W0LD24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1441930:Z042 RS22855
gene id: 1441930:Z042_RS22855
uniprot id: W0LG29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS12270
gene id: 1441930:Z042_RS12270
uniprot id: W0L922
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1441930:Z042 RS21995
gene id: 1441930:Z042_RS21995
uniprot id: W0LC41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1441930:Z042 RS13260
gene id: 1441930:Z042_RS13260
uniprot id: W0L9C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS12775
gene id: 1441930:Z042_RS12775
uniprot id: W0L4P2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS15365
gene id: 1441930:Z042_RS15365
uniprot id: W0L8C8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS00125
gene id: 1441930:Z042_RS00125
uniprot id: W0LF94
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1441930:Z042 RS06230
gene id: 1441930:Z042_RS06230
uniprot id: W0LCA8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1441930:Z042 RS05205
gene id: 1441930:Z042_RS05205
uniprot id: W0L8K4
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS09915
gene id: 1441930:Z042_RS09915
uniprot id: W0LAA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

1441930:Z042 RS18510
gene id: 1441930:Z042_RS18510
uniprot id: W0LI62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1441930:Z042 RS05225
gene id: 1441930:Z042_RS05225
uniprot id: W0LCQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1441930:Z042 RS06385
gene id: 1441930:Z042_RS06385
uniprot id: W0LD10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1441930:Z042 RS22905
gene id: 1441930:Z042_RS22905
uniprot id: W0LBL2
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS19720
gene id: 1441930:Z042_RS19720
uniprot id: W0LD91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS23965
gene id: 1441930:Z042_RS23965
uniprot id: W0LF69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS07165
gene id: 1441930:Z042_RS07165
uniprot id: A0A0D4ZXH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1441930:Z042 RS17365
gene id: 1441930:Z042_RS17365
uniprot id: W0LIF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1441930:Z042 RS20375
gene id: 1441930:Z042_RS20375
uniprot id: W0LI55
names: Similarity
messages: Belongs to the peptidase S11 family.

1441930:Z042 RS04310
gene id: 1441930:Z042_RS04310
uniprot id: W0L8R9
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

1441930:Z042 RS20680
gene id: 1441930:Z042_RS20680
uniprot id: W0LD28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1441930:Z042 RS21640
gene id: 1441930:Z042_RS21640
uniprot id: W0LGF8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1441930:Z042 RS10665
gene id: 1441930:Z042_RS10665
uniprot id: W0L5J2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS16140
gene id: 1441930:Z042_RS16140
uniprot id: W0LJF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1441930:Z042 RS05640
gene id: 1441930:Z042_RS05640
uniprot id: W0L846
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1441930:Z042 RS11430
gene id: 1441930:Z042_RS11430
uniprot id: W0L5E2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1441930:Z042 RS01400
gene id: 1441930:Z042_RS01400
uniprot id: W0LEL0
names: Function
names: Similarity
messages: Anion-transporting ATPase.
messages: Belongs to the arsA ATPase family.

1441930:Z042 RS22020
gene id: 1441930:Z042_RS22020
uniprot id: W0LGA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1441930:Z042 RS23675
gene id: 1441930:Z042_RS23675
uniprot id: W0LKQ6
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

1441930:Z042 RS19515
gene id: 1441930:Z042_RS19515
uniprot id: W0LIN2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1441930:Z042 RS11840
gene id: 1441930:Z042_RS11840
uniprot id: W0LA25
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1441930:Z042 RS10840
gene id: 1441930:Z042_RS10840
uniprot id: W0L5G0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1441930:Z042 RS14635
gene id: 1441930:Z042_RS14635
uniprot id: W0L3S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS08375
gene id: 1441930:Z042_RS08375
uniprot id: W0L6Y2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS05470
gene id: 1441930:Z042_RS05470
uniprot id: W0LC97
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS02620
gene id: 1441930:Z042_RS02620
uniprot id: W0LDP8
names: Similarity
messages: Belongs to the IMPACT family.

1441930:Z042 RS09925
gene id: 1441930:Z042_RS09925
uniprot id: W0LB43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1441930:Z042 RS12095
gene id: 1441930:Z042_RS12095
uniprot id: W0L8T2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1441930:Z042 RS02865
gene id: 1441930:Z042_RS02865
uniprot id: W0LEV4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1441930:Z042 RS05010
gene id: 1441930:Z042_RS05010
uniprot id: W0L8N4
names: Similarity
messages: Belongs to the UPF0438 family.

1441930:Z042 RS19535
gene id: 1441930:Z042_RS19535
uniprot id: W0LHN1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1441930:Z042 RS09860
gene id: 1441930:Z042_RS09860
uniprot id: W0L5X7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1441930:Z042 RS13500
gene id: 1441930:Z042_RS13500
uniprot id: W0L8I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

1441930:Z042 RS06240
gene id: 1441930:Z042_RS06240
uniprot id: W0LD58
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1441930:Z042 RS01210
gene id: 1441930:Z042_RS01210
uniprot id: W0LEP0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS07655
gene id: 1441930:Z042_RS07655
uniprot id: W0L728
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1441930:Z042 RS07190
gene id: 1441930:Z042_RS07190
uniprot id: W0LBD0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1441930:Z042 RS03200
gene id: 1441930:Z042_RS03200
uniprot id: W0L9D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
messages: Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS21080
gene id: 1441930:Z042_RS21080
uniprot id: W0LGP7
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

1441930:Z042 RS15245
gene id: 1441930:Z042_RS15245
uniprot id: A0A0D4ZXV4
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1441930:Z042 RS07800
gene id: 1441930:Z042_RS07800
uniprot id: W0LB08
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1441930:Z042 RS14050
gene id: 1441930:Z042_RS14050
uniprot id: W0L400
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1441930:Z042 RS18350
gene id: 1441930:Z042_RS18350
uniprot id: W0LHZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1441930:Z042 RS00930
gene id: 1441930:Z042_RS00930
uniprot id: W0LAE0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1441930:Z042 RS21290
gene id: 1441930:Z042_RS21290
uniprot id: A0A0D4ZXN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1441930:Z042 RS12990
gene id: 1441930:Z042_RS12990
uniprot id: W0L8C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS12795
gene id: 1441930:Z042_RS12795
uniprot id: W0L8T4
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS21520
gene id: 1441930:Z042_RS21520
uniprot id: W0LCN6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1441930:Z042 RS18910
gene id: 1441930:Z042_RS18910
uniprot id: W0LHR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS12675
gene id: 1441930:Z042_RS12675
uniprot id: W0L9L4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1441930:Z042 RS18900
gene id: 1441930:Z042_RS18900
uniprot id: W0LE17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1441930:Z042 RS16210
gene id: 1441930:Z042_RS16210
uniprot id: W0LJ52
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1441930:Z042 RS07455
gene id: 1441930:Z042_RS07455
uniprot id: W0LBL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

1441930:Z042 RS06915
gene id: 1441930:Z042_RS06915
uniprot id: W0LCR1
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1441930:Z042 RS16610
gene id: 1441930:Z042_RS16610
uniprot id: W0LEU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

1441930:Z042 RS09135
gene id: 1441930:Z042_RS09135
uniprot id: W0L6B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

1441930:Z042 RS02905
gene id: 1441930:Z042_RS02905
uniprot id: W0LDW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.

1441930:Z042 RS22495
gene id: 1441930:Z042_RS22495
uniprot id: W0LH72
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS04450
gene id: 1441930:Z042_RS04450
uniprot id: W0LD34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1441930:Z042 RS12070
gene id: 1441930:Z042_RS12070
uniprot id: W0L8T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1441930:Z042 RS15620
gene id: 1441930:Z042_RS15620
uniprot id: W0L7I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane
messages: Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.

1441930:Z042 RS21560
gene id: 1441930:Z042_RS21560
uniprot id: W0LHM9
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1441930:Z042 RS19780
gene id: 1441930:Z042_RS19780
uniprot id: W0LDI3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1441930:Z042 RS10525
gene id: 1441930:Z042_RS10525
uniprot id: W0L5U0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1441930:Z042 RS21565
gene id: 1441930:Z042_RS21565
uniprot id: W0LGG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1441930:Z042 RS19745
gene id: 1441930:Z042_RS19745
uniprot id: W0LD86
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1441930:Z042 RS22195
gene id: 1441930:Z042_RS22195
uniprot id: W0LG61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

1441930:Z042 RS10905
gene id: 1441930:Z042_RS10905
uniprot id: W0LAL1
names: Similarity
messages: Belongs to the autoinducer synthase family.

1441930:Z042 RS05430
gene id: 1441930:Z042_RS05430
uniprot id: W0LCN0
names: Similarity
messages: Belongs to the TPP enzyme family.

1441930:Z042 RS20300
gene id: 1441930:Z042_RS20300
uniprot id: W0LI71
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS19425
gene id: 1441930:Z042_RS19425
uniprot id: W0LKL7
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS01665
gene id: 1441930:Z042_RS01665
uniprot id: W0LE63
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1441930:Z042 RS02585
gene id: 1441930:Z042_RS02585
uniprot id: W0LE19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1441930:Z042 RS01585
gene id: 1441930:Z042_RS01585
uniprot id: W0LA37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

1441930:Z042 RS23050
gene id: 1441930:Z042_RS23050
uniprot id: W0LBU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1441930:Z042 RS09765
gene id: 1441930:Z042_RS09765
uniprot id: W0LAD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

1441930:Z042 RS04130
gene id: 1441930:Z042_RS04130
uniprot id: W0LD89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1441930:Z042 RS19660
gene id: 1441930:Z042_RS19660
uniprot id: W0LIK2
names: Similarity
messages: Belongs to the DDAH family.

1441930:Z042 RS00845
gene id: 1441930:Z042_RS00845
uniprot id: W0LAF5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS11760
gene id: 1441930:Z042_RS11760
uniprot id: W0L936
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1441930:Z042 RS19575
gene id: 1441930:Z042_RS19575
uniprot id: W0LDM6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS01985
gene id: 1441930:Z042_RS01985
uniprot id: W0LE01
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1441930:Z042 RS02520
gene id: 1441930:Z042_RS02520
uniprot id: W0L9Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1441930:Z042 RS01155
gene id: 1441930:Z042_RS01155
uniprot id: W0LA95
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.

1441930:Z042 RS18110
gene id: 1441930:Z042_RS18110
uniprot id: W0LJD6
names: Function
names: Similarity
messages: Belongs to the arginine N-succinyltransferase family.
messages: Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.

1441930:Z042 RS12560
gene id: 1441930:Z042_RS12560
uniprot id: W0L9N6
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS08810
gene id: 1441930:Z042_RS08810
uniprot id: W0LAK5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1441930:Z042 RS15015
gene id: 1441930:Z042_RS15015
uniprot id: W0L3I8
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1441930:Z042 RS20500
gene id: 1441930:Z042_RS20500
uniprot id: W0LCU7
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1441930:Z042 RS21075
gene id: 1441930:Z042_RS21075
uniprot id: W0LHU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1441930:Z042 RS07920
gene id: 1441930:Z042_RS07920
uniprot id: W0LC68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1441930:Z042 RS21895
gene id: 1441930:Z042_RS21895
uniprot id: W0LGB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1441930:Z042 RS16475
gene id: 1441930:Z042_RS16475
uniprot id: W0LEW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

1441930:Z042 RS16450
gene id: 1441930:Z042_RS16450
uniprot id: W0LEX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS21400
gene id: 1441930:Z042_RS21400
uniprot id: W0LGJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.

1441930:Z042 RS23375
gene id: 1441930:Z042_RS23375
uniprot id: W0LBN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1441930:Z042 RS02510
gene id: 1441930:Z042_RS02510
uniprot id: W0L9N0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1441930:Z042 RS16085
gene id: 1441930:Z042_RS16085
uniprot id: W0LJG2
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

1441930:Z042 RS04300
gene id: 1441930:Z042_RS04300
uniprot id: A0A0D4ZYB2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1441930:Z042 RS02480
gene id: 1441930:Z042_RS02480
uniprot id: W0LDR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1441930:Z042 RS15785
gene id: 1441930:Z042_RS15785
uniprot id: W0LJL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

1441930:Z042 RS13020
gene id: 1441930:Z042_RS13020
uniprot id: W0L8C5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1441930:Z042 RS02690
gene id: 1441930:Z042_RS02690
uniprot id: W0LEY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1441930:Z042 RS14890
gene id: 1441930:Z042_RS14890
uniprot id: W0L7W2
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS16220
gene id: 1441930:Z042_RS16220
uniprot id: W0LF09
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS07585
gene id: 1441930:Z042_RS07585
uniprot id: W0L742
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS05625
gene id: 1441930:Z042_RS05625
uniprot id: W0L8D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1441930:Z042 RS09780
gene id: 1441930:Z042_RS09780
uniprot id: W0LA14
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS23450
gene id: 1441930:Z042_RS23450
uniprot id: W0LBM6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1441930:Z042 RS16740
gene id: 1441930:Z042_RS16740
uniprot id: W0LK39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

1441930:Z042 RS17275
gene id: 1441930:Z042_RS17275
uniprot id: W0LIS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1441930:Z042 RS17405
gene id: 1441930:Z042_RS17405
uniprot id: W0LEQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1441930:Z042 RS04470
gene id: 1441930:Z042_RS04470
uniprot id: W0L8P4
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

1441930:Z042 RS03800
gene id: 1441930:Z042_RS03800
uniprot id: W0LED0
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

1441930:Z042 RS23210
gene id: 1441930:Z042_RS23210
uniprot id: W0LGT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS15855
gene id: 1441930:Z042_RS15855
uniprot id: W0LFL6
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.

1441930:Z042 RS09920
gene id: 1441930:Z042_RS09920
uniprot id: W0L643
names: Similarity
messages: Belongs to the skp family.

1441930:Z042 RS07065
gene id: 1441930:Z042_RS07065
uniprot id: W0LBT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

1441930:Z042 RS02950
gene id: 1441930:Z042_RS02950
uniprot id: W0LEU0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS09455
gene id: 1441930:Z042_RS09455
uniprot id: W0LBD4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1441930:Z042 RS22325
gene id: 1441930:Z042_RS22325
uniprot id: W0LBV5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1441930:Z042 RS18540
gene id: 1441930:Z042_RS18540
uniprot id: W0LE76
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1441930:Z042 RS02465
gene id: 1441930:Z042_RS02465
uniprot id: W0LE40
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

1441930:Z042 RS07625
gene id: 1441930:Z042_RS07625
uniprot id: W0LB47
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1441930:Z042 RS05180
gene id: 1441930:Z042_RS05180
uniprot id: W0L8K7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1441930:Z042 RS20930
gene id: 1441930:Z042_RS20930
uniprot id: W0LH30
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1441930:Z042 RS07740
gene id: 1441930:Z042_RS07740
uniprot id: W0L780
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Belongs to the Nudix hydrolase family. NudK subfamily.
messages: Homodimer.
messages: Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.

1441930:Z042 RS21510
gene id: 1441930:Z042_RS21510
uniprot id: W0LCA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1441930:Z042 RS05730
gene id: 1441930:Z042_RS05730
uniprot id: W0LCJ1
names: Similarity
messages: Belongs to the HSP15 family.

1441930:Z042 RS23990
gene id: 1441930:Z042_RS23990
uniprot id: W0LF65
names: Similarity
messages: Belongs to the SurE nucleotidase family.

1441930:Z042 RS04525
gene id: 1441930:Z042_RS04525
uniprot id: W0LD22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1441930:Z042 RS10860
gene id: 1441930:Z042_RS10860
uniprot id: W0L9F9
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS16495
gene id: 1441930:Z042_RS16495
uniprot id: W0LJ05
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1441930:Z042 RS19595
gene id: 1441930:Z042_RS19595
uniprot id: W0LHM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1441930:Z042 RS04750
gene id: 1441930:Z042_RS04750
uniprot id: W0LCL3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1441930:Z042 RS03160
gene id: 1441930:Z042_RS03160
uniprot id: W0L9N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzyE family.
messages: Cell inner membrane
messages: Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

1441930:Z042 RS10970
gene id: 1441930:Z042_RS10970
uniprot id: W0L5L9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1441930:Z042 RS01460
gene id: 1441930:Z042_RS01460
uniprot id: W0LEK2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1441930:Z042 RS15105
gene id: 1441930:Z042_RS15105
uniprot id: W0L7F0
names: Similarity
messages: Belongs to the UPF0229 family.

1441930:Z042 RS18105
gene id: 1441930:Z042_RS18105
uniprot id: W0LEF8
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

1441930:Z042 RS06045
gene id: 1441930:Z042_RS06045
uniprot id: W0LC03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1441930:Z042 RS18460
gene id: 1441930:Z042_RS18460
uniprot id: W0LI72
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1441930:Z042 RS14020
gene id: 1441930:Z042_RS14020
uniprot id: W0L7Y1
names: Similarity
messages: Belongs to the proline racemase family.

1441930:Z042 RS05040
gene id: 1441930:Z042_RS05040
uniprot id: W0LDQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1441930:Z042 RS10845
gene id: 1441930:Z042_RS10845
uniprot id: W0L9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS03855
gene id: 1441930:Z042_RS03855
uniprot id: W0LD32
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

1441930:Z042 RS05435
gene id: 1441930:Z042_RS05435
uniprot id: W0L8H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

1441930:Z042 RS01185
gene id: 1441930:Z042_RS01185
uniprot id: W0LEP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1441930:Z042 RS02610
gene id: 1441930:Z042_RS02610
uniprot id: W0L9X9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Belongs to the flavodoxin family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

1441930:Z042 RS07565
gene id: 1441930:Z042_RS07565
uniprot id: W0L7A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

1441930:Z042 RS14675
gene id: 1441930:Z042_RS14675
uniprot id: W0L8U1
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS13355
gene id: 1441930:Z042_RS13355
uniprot id: W0L9B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS02670
gene id: 1441930:Z042_RS02670
uniprot id: W0LDN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1441930:Z042 RS12600
gene id: 1441930:Z042_RS12600
uniprot id: W0L8X0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.
messages: Belongs to the RcsC family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
messages: Interacts with RcsD.

1441930:Z042 RS15115
gene id: 1441930:Z042_RS15115
uniprot id: W0L7R9
names: Similarity
messages: Belongs to the MipA/OmpV family.

1441930:Z042 RS05720
gene id: 1441930:Z042_RS05720
uniprot id: W0LC62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

1441930:Z042 RS15540
gene id: 1441930:Z042_RS15540
uniprot id: W0L7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1441930:Z042 RS11560
gene id: 1441930:Z042_RS11560
uniprot id: W0L549
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS04440
gene id: 1441930:Z042_RS04440
uniprot id: W0LCS8
names: Similarity
messages: Belongs to the YicC/YloC family.

1441930:Z042 RS22235
gene id: 1441930:Z042_RS22235
uniprot id: W0LC80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1441930:Z042 RS02505
gene id: 1441930:Z042_RS02505
uniprot id: W0LDR1
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS11290
gene id: 1441930:Z042_RS11290
uniprot id: W0L587
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

1441930:Z042 RS18820
gene id: 1441930:Z042_RS18820
uniprot id: W0LJ16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1441930:Z042 RS00855
gene id: 1441930:Z042_RS00855
uniprot id: W0LAQ4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1441930:Z042 RS06715
gene id: 1441930:Z042_RS06715
uniprot id: W0LCV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.
messages: Electron-transport protein of unknown function.

1441930:Z042 RS03115
gene id: 1441930:Z042_RS03115
uniprot id: W0LER5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1441930:Z042 RS22615
gene id: 1441930:Z042_RS22615
uniprot id: W0LH53
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1441930:Z042 RS06225
gene id: 1441930:Z042_RS06225
uniprot id: W0L7V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1441930:Z042 RS20780
gene id: 1441930:Z042_RS20780
uniprot id: W0LHY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1441930:Z042 RS18410
gene id: 1441930:Z042_RS18410
uniprot id: W0LI82
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1441930:Z042 RS00315
gene id: 1441930:Z042_RS00315
uniprot id: W0LF64
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1441930:Z042 RS08720
gene id: 1441930:Z042_RS08720
uniprot id: W0L6T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

1441930:Z042 RS16750
gene id: 1441930:Z042_RS16750
uniprot id: W0LEP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

1441930:Z042 RS04740
gene id: 1441930:Z042_RS04740
uniprot id: W0L8R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1441930:Z042 RS16360
gene id: 1441930:Z042_RS16360
uniprot id: W0LFC3
names: Similarity
messages: Belongs to the ribulokinase family.

1441930:Z042 RS22165
gene id: 1441930:Z042_RS22165
uniprot id: W0LHE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS05480
gene id: 1441930:Z042_RS05480
uniprot id: W0L874
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1441930:Z042 RS08520
gene id: 1441930:Z042_RS08520
uniprot id: W0LB19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

1441930:Z042 RS19255
gene id: 1441930:Z042_RS19255
uniprot id: W0LHU8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1441930:Z042 RS11510
gene id: 1441930:Z042_RS11510
uniprot id: W0L5C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

1441930:Z042 RS20915
gene id: 1441930:Z042_RS20915
uniprot id: W0LHW3
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1441930:Z042 RS04460
gene id: 1441930:Z042_RS04460
uniprot id: W0LDZ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1441930:Z042 RS00495
gene id: 1441930:Z042_RS00495
uniprot id: W0LG28
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1441930:Z042 RS03155
gene id: 1441930:Z042_RS03155
uniprot id: W0LDS3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.

1441930:Z042 RS24090
gene id: 1441930:Z042_RS24090
uniprot id: W0LGD2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS04630
gene id: 1441930:Z042_RS04630
uniprot id: W0LD03
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Activates expression of the rhaBAD and rhaT operons.
messages: Binds DNA as a dimer.
messages: Cytoplasm

1441930:Z042 RS20115
gene id: 1441930:Z042_RS20115
uniprot id: W0LHE4
names: Similarity
messages: Belongs to the FGGY kinase family.

1441930:Z042 RS03010
gene id: 1441930:Z042_RS03010
uniprot id: W0LDI4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1441930:Z042 RS03175
gene id: 1441930:Z042_RS03175
uniprot id: W0L9D3
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

1441930:Z042 RS11130
gene id: 1441930:Z042_RS11130
uniprot id: W0LAH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1441930:Z042 RS02370
gene id: 1441930:Z042_RS02370
uniprot id: A0A0D4ZY01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS01635
gene id: 1441930:Z042_RS01635
uniprot id: W0LFF9
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1441930:Z042 RS06895
gene id: 1441930:Z042_RS06895
uniprot id: W0LBI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS17205
gene id: 1441930:Z042_RS17205
uniprot id: W0LII5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

1441930:Z042 RS11910
gene id: 1441930:Z042_RS11910
uniprot id: W0L539
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1441930:Z042 RS10820
gene id: 1441930:Z042_RS10820
uniprot id: W0L9T8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1441930:Z042 RS23410
gene id: 1441930:Z042_RS23410
uniprot id: W0LFG8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1441930:Z042 RS18600
gene id: 1441930:Z042_RS18600
uniprot id: W0LHV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS22545
gene id: 1441930:Z042_RS22545
uniprot id: W0LFY8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Homotetramer.

1441930:Z042 RS05880
gene id: 1441930:Z042_RS05880
uniprot id: W0LCH2
names: Similarity
messages: Belongs to the UPF0270 family.

1441930:Z042 RS05710
gene id: 1441930:Z042_RS05710
uniprot id: W0L8C6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1441930:Z042 RS08135
gene id: 1441930:Z042_RS08135
uniprot id: W0L717
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1441930:Z042 RS08680
gene id: 1441930:Z042_RS08680
uniprot id: W0LAM6
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1441930:Z042 RS09025
gene id: 1441930:Z042_RS09025
uniprot id: W0LAG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1441930:Z042 RS02810
gene id: 1441930:Z042_RS02810
uniprot id: W0L9U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS04035
gene id: 1441930:Z042_RS04035
uniprot id: W0LD01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS02625
gene id: 1441930:Z042_RS02625
uniprot id: W0L9L7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

1441930:Z042 RS11245
gene id: 1441930:Z042_RS11245
uniprot id: W0L5H6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1441930:Z042 RS16270
gene id: 1441930:Z042_RS16270
uniprot id: W0LKD8
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1441930:Z042 RS03840
gene id: 1441930:Z042_RS03840
uniprot id: W0LDD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS04395
gene id: 1441930:Z042_RS04395
uniprot id: W0L8Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1441930:Z042 RS23105
gene id: 1441930:Z042_RS23105
uniprot id: W0LBT1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1441930:Z042 RS09095
gene id: 1441930:Z042_RS09095
uniprot id: W0L6J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
messages: Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS11355
gene id: 1441930:Z042_RS11355
uniprot id: W0L5F7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS23155
gene id: 1441930:Z042_RS23155
uniprot id: W0LGU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1441930:Z042 RS18400
gene id: 1441930:Z042_RS18400
uniprot id: W0LHY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1441930:Z042 RS00420
gene id: 1441930:Z042_RS00420
uniprot id: W0LKM2
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS11395
gene id: 1441930:Z042_RS11395
uniprot id: W0L571
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

1441930:Z042 RS00750
gene id: 1441930:Z042_RS00750
uniprot id: W0LEN0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1441930:Z042 RS12370
gene id: 1441930:Z042_RS12370
uniprot id: W0L910
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1441930:Z042 RS07345
gene id: 1441930:Z042_RS07345
uniprot id: W0LBA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1441930:Z042 RS07805
gene id: 1441930:Z042_RS07805
uniprot id: W0L701
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS22050
gene id: 1441930:Z042_RS22050
uniprot id: W0LC33
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1441930:Z042 RS18505
gene id: 1441930:Z042_RS18505
uniprot id: W0LDV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1441930:Z042 RS20515
gene id: 1441930:Z042_RS20515
uniprot id: W0LI30
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1441930:Z042 RS13555
gene id: 1441930:Z042_RS13555
uniprot id: W0L4D1
names: Similarity
messages: Belongs to the acylphosphatase family.

1441930:Z042 RS12005
gene id: 1441930:Z042_RS12005
uniprot id: W0L969
names: Similarity
messages: Belongs to the MlaA family.

1441930:Z042 RS03230
gene id: 1441930:Z042_RS03230
uniprot id: W0LDQ9
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

1441930:Z042 RS11985
gene id: 1441930:Z042_RS11985
uniprot id: W0L8V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS22865
gene id: 1441930:Z042_RS22865
uniprot id: W0LH07
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1441930:Z042 RS04190
gene id: 1441930:Z042_RS04190
uniprot id: W0LE41
names: Similarity
names: Subunit
messages: Belongs to the ViaA family.
messages: Possible formation of a ternary complex RavA-ViaA-CadA.

1441930:Z042 RS20700
gene id: 1441930:Z042_RS20700
uniprot id: W0LH66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1441930:Z042 RS13455
gene id: 1441930:Z042_RS13455
uniprot id: W0L861
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1441930:Z042 RS23400
gene id: 1441930:Z042_RS23400
uniprot id: W0LBN2
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1441930:Z042 RS12655
gene id: 1441930:Z042_RS12655
uniprot id: W0L8J0
names: Similarity
messages: Belongs to the UPF0352 family.

1441930:Z042 RS14495
gene id: 1441930:Z042_RS14495
uniprot id: W0L3U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

1441930:Z042 RS01645
gene id: 1441930:Z042_RS01645
uniprot id: W0LA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1441930:Z042 RS13340
gene id: 1441930:Z042_RS13340
uniprot id: W0L8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1441930:Z042 RS00365
gene id: 1441930:Z042_RS00365
uniprot id: W0LF56
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

1441930:Z042 RS19725
gene id: 1441930:Z042_RS19725
uniprot id: W0LHJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS18695
gene id: 1441930:Z042_RS18695
uniprot id: W0LJ39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

1441930:Z042 RS20090
gene id: 1441930:Z042_RS20090
uniprot id: W0LHE8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS17025
gene id: 1441930:Z042_RS17025
uniprot id: W0LIW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1441930:Z042 RS21845
gene id: 1441930:Z042_RS21845
uniprot id: W0LGC7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1441930:Z042 RS18680
gene id: 1441930:Z042_RS18680
uniprot id: W0LDS5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1441930:Z042 RS23140
gene id: 1441930:Z042_RS23140
uniprot id: W0LFL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1441930:Z042 RS13900
gene id: 1441930:Z042_RS13900
uniprot id: W0L428
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1441930:Z042 RS03985
gene id: 1441930:Z042_RS03985
uniprot id: W0LD09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS06075
gene id: 1441930:Z042_RS06075
uniprot id: W0L7X6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1441930:Z042 RS22540
gene id: 1441930:Z042_RS22540
uniprot id: W0LH67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1441930:Z042 RS21665
gene id: 1441930:Z042_RS21665
uniprot id: W0LHL6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1441930:Z042 RS05925
gene id: 1441930:Z042_RS05925
uniprot id: W0L7Z6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1441930:Z042 RS10955
gene id: 1441930:Z042_RS10955
uniprot id: W0L9E8
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

1441930:Z042 RS17915
gene id: 1441930:Z042_RS17915
uniprot id: W0LEI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1441930:Z042 RS01575
gene id: 1441930:Z042_RS01575
uniprot id: W0LFG9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1441930:Z042 RS02395
gene id: 1441930:Z042_RS02395
uniprot id: W0LDT0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1441930:Z042 RS00990
gene id: 1441930:Z042_RS00990
uniprot id: W0LAN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1441930:Z042 RS21550
gene id: 1441930:Z042_RS21550
uniprot id: W0LCN1
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS21410
gene id: 1441930:Z042_RS21410
uniprot id: W0LGV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm
messages: Homohexamer.

1441930:Z042 RS20970
gene id: 1441930:Z042_RS20970
uniprot id: W0LGR3
names: Similarity
messages: Belongs to the asparagine synthetase family.

1441930:Z042 RS12745
gene id: 1441930:Z042_RS12745
uniprot id: W0L8U4
names: Similarity
messages: Belongs to the elongation factor P family.

1441930:Z042 RS14895
gene id: 1441930:Z042_RS14895
uniprot id: W0L3Q8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS08865
gene id: 1441930:Z042_RS08865
uniprot id: W0L6J0
names: Function
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.
messages: Catalyzes the formation of putrescine from agmatine.

1441930:Z042 RS08795
gene id: 1441930:Z042_RS08795
uniprot id: W0LAX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1441930:Z042 RS06015
gene id: 1441930:Z042_RS06015
uniprot id: W0LD95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1441930:Z042 RS12230
gene id: 1441930:Z042_RS12230
uniprot id: W0L8R3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS13785
gene id: 1441930:Z042_RS13785
uniprot id: W0L966
names: Similarity
messages: Belongs to the Gfa family.

1441930:Z042 RS20585
gene id: 1441930:Z042_RS20585
uniprot id: W0LD41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1441930:Z042 RS14530
gene id: 1441930:Z042_RS14530
uniprot id: W0L403
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1441930:Z042 RS18790
gene id: 1441930:Z042_RS18790
uniprot id: W0LE32
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. MukB subfamily.
messages: Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.
messages: Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
messages: The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
messages: nucleoid

1441930:Z042 RS22425
gene id: 1441930:Z042_RS22425
uniprot id: W0LG06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

1441930:Z042 RS04530
gene id: 1441930:Z042_RS04530
uniprot id: W0L8V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1441930:Z042 RS17035
gene id: 1441930:Z042_RS17035
uniprot id: W0LJX4
names: Function
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate.

1441930:Z042 RS12770
gene id: 1441930:Z042_RS12770
uniprot id: W0L8T9
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1441930:Z042 RS10505
gene id: 1441930:Z042_RS10505
uniprot id: W0LAT4
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

1441930:Z042 RS13740
gene id: 1441930:Z042_RS13740
uniprot id: W0L820
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS04680
gene id: 1441930:Z042_RS04680
uniprot id: W0L8K3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

1441930:Z042 RS15390
gene id: 1441930:Z042_RS15390
uniprot id: W0L8C2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1441930:Z042 RS06330
gene id: 1441930:Z042_RS06330
uniprot id: W0LBU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS21490
gene id: 1441930:Z042_RS21490
uniprot id: W0LCP1
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS02575
gene id: 1441930:Z042_RS02575
uniprot id: W0LDQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1441930:Z042 RS10805
gene id: 1441930:Z042_RS10805
uniprot id: W0LAM9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1441930:Z042 RS00880
gene id: 1441930:Z042_RS00880
uniprot id: W0LAQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1441930:Z042 RS00955
gene id: 1441930:Z042_RS00955
uniprot id: W0LAD6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1441930:Z042 RS04615
gene id: 1441930:Z042_RS04615
uniprot id: W0LDW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm
messages: Homotetramer.

1441930:Z042 RS13390
gene id: 1441930:Z042_RS13390
uniprot id: W0L4F8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1441930:Z042 RS12610
gene id: 1441930:Z042_RS12610
uniprot id: W0L9M5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RcsD family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
messages: Interacts with RcsC and RcsB.
messages: Phosphorylated by RcsC.

1441930:Z042 RS23560
gene id: 1441930:Z042_RS23560
uniprot id: W0LFD6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1441930:Z042 RS21095
gene id: 1441930:Z042_RS21095
uniprot id: W0LH09
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1441930:Z042 RS12905
gene id: 1441930:Z042_RS12905
uniprot id: W0L8R6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS22415
gene id: 1441930:Z042_RS22415
uniprot id: W0LC49
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1441930:Z042 RS23595
gene id: 1441930:Z042_RS23595
uniprot id: W0LB77
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1441930:Z042 RS17970
gene id: 1441930:Z042_RS17970
uniprot id: W0LIG4
names: Similarity
messages: Belongs to the UPF0181 family.

1441930:Z042 RS00800
gene id: 1441930:Z042_RS00800
uniprot id: W0LFW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1441930:Z042 RS02770
gene id: 1441930:Z042_RS02770
uniprot id: W0LDM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1441930:Z042 RS01140
gene id: 1441930:Z042_RS01140
uniprot id: W0LAK0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1441930:Z042 RS23485
gene id: 1441930:Z042_RS23485
uniprot id: W0LFF2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1441930:Z042 RS20740
gene id: 1441930:Z042_RS20740
uniprot id: W0LCQ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1441930:Z042 RS07465
gene id: 1441930:Z042_RS07465
uniprot id: W0LCE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS15000
gene id: 1441930:Z042_RS15000
uniprot id: W0L3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell membrane
messages: Forms a complex with MdtJ.
messages: Membrane

1441930:Z042 RS16305
gene id: 1441930:Z042_RS16305
uniprot id: W0LEZ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

1441930:Z042 RS03750
gene id: 1441930:Z042_RS03750
uniprot id: W0LD51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1441930:Z042 RS18360
gene id: 1441930:Z042_RS18360
uniprot id: W0LI92
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1441930:Z042 RS14795
gene id: 1441930:Z042_RS14795
uniprot id: W0L7M0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1441930:Z042 RS03505
gene id: 1441930:Z042_RS03505
uniprot id: W0L965
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS06440
gene id: 1441930:Z042_RS06440
uniprot id: W0LBR6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1441930:Z042 RS23435
gene id: 1441930:Z042_RS23435
uniprot id: W0LFG3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1441930:Z042 RS12260
gene id: 1441930:Z042_RS12260
uniprot id: W0L8Q6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS16635
gene id: 1441930:Z042_RS16635
uniprot id: W0LEU1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1441930:Z042 RS09315
gene id: 1441930:Z042_RS09315
uniprot id: W0LA92
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS03060
gene id: 1441930:Z042_RS03060
uniprot id: W0L9Q0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1441930:Z042 RS04570
gene id: 1441930:Z042_RS04570
uniprot id: W0L8M5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1441930:Z042 RS18430
gene id: 1441930:Z042_RS18430
uniprot id: W0LDX3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1441930:Z042 RS15045
gene id: 1441930:Z042_RS15045
uniprot id: W0L7T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1441930:Z042 RS04065
gene id: 1441930:Z042_RS04065
uniprot id: W0L8W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

1441930:Z042 RS03850
gene id: 1441930:Z042_RS03850
uniprot id: W0LEC0
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1441930:Z042 RS23520
gene id: 1441930:Z042_RS23520
uniprot id: W0LFR0
names: Similarity
messages: Belongs to the threonine synthase family.

1441930:Z042 RS22260
gene id: 1441930:Z042_RS22260
uniprot id: W0LC75
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1441930:Z042 RS20845
gene id: 1441930:Z042_RS20845
uniprot id: W0LH41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1441930:Z042 RS15505
gene id: 1441930:Z042_RS15505
uniprot id: W0L393
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1441930:Z042 RS11470
gene id: 1441930:Z042_RS11470
uniprot id: W0L562
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS06020
gene id: 1441930:Z042_RS06020
uniprot id: W0LC07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1441930:Z042 RS09325
gene id: 1441930:Z042_RS09325
uniprot id: W0L674
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1441930:Z042 RS18995
gene id: 1441930:Z042_RS18995
uniprot id: W0LDM8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1441930:Z042 RS20475
gene id: 1441930:Z042_RS20475
uniprot id: W0LH99
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS11720
gene id: 1441930:Z042_RS11720
uniprot id: W0LA85
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1441930:Z042 RS10695
gene id: 1441930:Z042_RS10695
uniprot id: W0L9W3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: 4-aminobutanal can spontaneously cyclize to 1-pyrroline, and 5-aminopentanal to 1-piperideine.
messages: Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
messages: Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
messages: Homotetramer.

1441930:Z042 RS19100
gene id: 1441930:Z042_RS19100
uniprot id: W0LHX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS18395
gene id: 1441930:Z042_RS18395
uniprot id: W0LJ88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1441930:Z042 RS14900
gene id: 1441930:Z042_RS14900
uniprot id: W0L8M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1441930:Z042 RS04685
gene id: 1441930:Z042_RS04685
uniprot id: W0LCZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1441930:Z042 RS10245
gene id: 1441930:Z042_RS10245
uniprot id: W0L5Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1441930:Z042 RS15005
gene id: 1441930:Z042_RS15005
uniprot id: W0L8K1
names: Similarity
messages: Belongs to the RutC family.

1441930:Z042 RS04075
gene id: 1441930:Z042_RS04075
uniprot id: W0L929
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS07590
gene id: 1441930:Z042_RS07590
uniprot id: W0LBI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1441930:Z042 RS09855
gene id: 1441930:Z042_RS09855
uniprot id: W0L9Z9
names: Similarity
messages: Belongs to the UPF0325 family.

1441930:Z042 RS18860
gene id: 1441930:Z042_RS18860
uniprot id: W0LI00
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1441930:Z042 RS15250
gene id: 1441930:Z042_RS15250
uniprot id: W0L8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS12460
gene id: 1441930:Z042_RS12460
uniprot id: W0L9Q9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1441930:Z042 RS09300
gene id: 1441930:Z042_RS09300
uniprot id: W0LAK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1441930:Z042 RS09150
gene id: 1441930:Z042_RS09150
uniprot id: W0LBJ4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1441930:Z042 RS00180
gene id: 1441930:Z042_RS00180
uniprot id: W0LB51
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS08805
gene id: 1441930:Z042_RS08805
uniprot id: W0LBT4
names: Similarity
messages: Belongs to the SfsA family.

1441930:Z042 RS14935
gene id: 1441930:Z042_RS14935
uniprot id: W0L3K3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1441930:Z042 RS14940
gene id: 1441930:Z042_RS14940
uniprot id: W0L7V1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1441930:Z042 RS15185
gene id: 1441930:Z042_RS15185
uniprot id: W0L3F4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1441930:Z042 RS21045
gene id: 1441930:Z042_RS21045
uniprot id: W0LHU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS01650
gene id: 1441930:Z042_RS01650
uniprot id: W0LEH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1441930:Z042 RS11215
gene id: 1441930:Z042_RS11215
uniprot id: W0LAG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1441930:Z042 RS03330
gene id: 1441930:Z042_RS03330
uniprot id: W0L9B4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1441930:Z042 RS14340
gene id: 1441930:Z042_RS14340
uniprot id: W0L7U2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1441930:Z042 RS17300
gene id: 1441930:Z042_RS17300
uniprot id: W0LIR8
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

1441930:Z042 RS07010
gene id: 1441930:Z042_RS07010
uniprot id: W0L7D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1441930:Z042 RS13560
gene id: 1441930:Z042_RS13560
uniprot id: W0L990
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

1441930:Z042 RS16100
gene id: 1441930:Z042_RS16100
uniprot id: W0LJ68
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS18000
gene id: 1441930:Z042_RS18000
uniprot id: W0LEH7
names: Similarity
messages: Belongs to the UPF0053 family.

1441930:Z042 RS08705
gene id: 1441930:Z042_RS08705
uniprot id: W0LAM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1441930:Z042 RS05020
gene id: 1441930:Z042_RS05020
uniprot id: W0LCG4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1441930:Z042 RS21420
gene id: 1441930:Z042_RS21420
uniprot id: W0LHP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
messages: Cytoplasm
messages: Homodecamer.
messages: Involved in the anomeric conversion of L-fucose.

1441930:Z042 RS16090
gene id: 1441930:Z042_RS16090
uniprot id: W0LFH1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS21735
gene id: 1441930:Z042_RS21735
uniprot id: W0LCJ6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1441930:Z042 RS06620
gene id: 1441930:Z042_RS06620
uniprot id: W0LBN1
names: Similarity
messages: Belongs to the peptidase U62 family.

1441930:Z042 RS09365
gene id: 1441930:Z042_RS09365
uniprot id: W0LAJ9
names: Similarity
messages: Belongs to the peptidase S14 family.

1441930:Z042 RS07100
gene id: 1441930:Z042_RS07100
uniprot id: W0LCM3
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS11320
gene id: 1441930:Z042_RS11320
uniprot id: W0L584
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1441930:Z042 RS21805
gene id: 1441930:Z042_RS21805
uniprot id: W0LGN9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1441930:Z042 RS14505
gene id: 1441930:Z042_RS14505
uniprot id: W0L408
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1441930:Z042 RS24375
gene id: 1441930:Z042_RS24375
uniprot id: W0LFC0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1441930:Z042 RS13970
gene id: 1441930:Z042_RS13970
uniprot id: W0L7Y9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS19690
gene id: 1441930:Z042_RS19690
uniprot id: W0LHE0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1441930:Z042 RS20240
gene id: 1441930:Z042_RS20240
uniprot id: W0LDA0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1441930:Z042 RS02815
gene id: 1441930:Z042_RS02815
uniprot id: W0LEW6
names: Similarity
messages: Belongs to the leucine-binding protein family.

1441930:Z042 RS19655
gene id: 1441930:Z042_RS19655
uniprot id: W0LDL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1441930:Z042 RS02695
gene id: 1441930:Z042_RS02695
uniprot id: W0LDN2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1441930:Z042 RS15395
gene id: 1441930:Z042_RS15395
uniprot id: W0L797
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1441930:Z042 RS03905
gene id: 1441930:Z042_RS03905
uniprot id: W0LD23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1441930:Z042 RS00805
gene id: 1441930:Z042_RS00805
uniprot id: W0LEL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1441930:Z042 RS03105
gene id: 1441930:Z042_RS03105
uniprot id: W0LDS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

1441930:Z042 RS02685
gene id: 1441930:Z042_RS02685
uniprot id: W0L9W4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS17905
gene id: 1441930:Z042_RS17905
uniprot id: W0LE74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance.
messages: Membrane

1441930:Z042 RS10880
gene id: 1441930:Z042_RS10880
uniprot id: W0LAL5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1441930:Z042 RS19565
gene id: 1441930:Z042_RS19565
uniprot id: W0LDB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

1441930:Z042 RS12700
gene id: 1441930:Z042_RS12700
uniprot id: W0L4Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS10460
gene id: 1441930:Z042_RS10460
uniprot id: W0L9N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1441930:Z042 RS23420
gene id: 1441930:Z042_RS23420
uniprot id: W0LFS8
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1441930:Z042 RS16135
gene id: 1441930:Z042_RS16135
uniprot id: W0LF20
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS18340
gene id: 1441930:Z042_RS18340
uniprot id: W0LEB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1441930:Z042 RS08995
gene id: 1441930:Z042_RS08995
uniprot id: W0LAH4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1441930:Z042 RS23630
gene id: 1441930:Z042_RS23630
uniprot id: W0LFP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1441930:Z042 RS05305
gene id: 1441930:Z042_RS05305
uniprot id: W0LCB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
messages: Membrane

1441930:Z042 RS21310
gene id: 1441930:Z042_RS21310
uniprot id: W0LCE3
names: Similarity
messages: Belongs to the UxaA family.

1441930:Z042 RS19380
gene id: 1441930:Z042_RS19380
uniprot id: W0LIT0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

1441930:Z042 RS07030
gene id: 1441930:Z042_RS07030
uniprot id: W0LBG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

1441930:Z042 RS11990
gene id: 1441930:Z042_RS11990
uniprot id: W0L4X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1441930:Z042 RS10745
gene id: 1441930:Z042_RS10745
uniprot id: W0L9V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS13805
gene id: 1441930:Z042_RS13805
uniprot id: A0A0D4ZYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS08590
gene id: 1441930:Z042_RS08590
uniprot id: W0LBX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1441930:Z042 RS03125
gene id: 1441930:Z042_RS03125
uniprot id: W0L9D6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1441930:Z042 RS17985
gene id: 1441930:Z042_RS17985
uniprot id: W0LI64
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

1441930:Z042 RS20770
gene id: 1441930:Z042_RS20770
uniprot id: W0LH54
names: Similarity
messages: Belongs to the citrate synthase family.

1441930:Z042 RS16255
gene id: 1441930:Z042_RS16255
uniprot id: W0LJD4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1441930:Z042 RS11085
gene id: 1441930:Z042_RS11085
uniprot id: W0L5C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS16785
gene id: 1441930:Z042_RS16785
uniprot id: W0LF18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1441930:Z042 RS06815
gene id: 1441930:Z042_RS06815
uniprot id: W0LCT1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1441930:Z042 RS18960
gene id: 1441930:Z042_RS18960
uniprot id: W0LIZ3
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

1441930:Z042 RS07620
gene id: 1441930:Z042_RS07620
uniprot id: W0LCB9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS22825
gene id: 1441930:Z042_RS22825
uniprot id: W0LGD8
names: Similarity
messages: Belongs to the phage antitermination Q type 1 family.

1441930:Z042 RS04775
gene id: 1441930:Z042_RS04775
uniprot id: W0LCK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

1441930:Z042 RS08075
gene id: 1441930:Z042_RS08075
uniprot id: W0L6V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1441930:Z042 RS01670
gene id: 1441930:Z042_RS01670
uniprot id: W0LA23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

1441930:Z042 RS07180
gene id: 1441930:Z042_RS07180
uniprot id: W0L7H8
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1441930:Z042 RS16725
gene id: 1441930:Z042_RS16725
uniprot id: A0A0D4ZXT5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS04745
gene id: 1441930:Z042_RS04745
uniprot id: W0LDT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1441930:Z042 RS15750
gene id: 1441930:Z042_RS15750
uniprot id: W0LJC4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1441930:Z042 RS11420
gene id: 1441930:Z042_RS11420
uniprot id: W0L568
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1441930:Z042 RS02265
gene id: 1441930:Z042_RS02265
uniprot id: W0L9S7
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family.
messages: Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria.

1441930:Z042 RS23495
gene id: 1441930:Z042_RS23495
uniprot id: W0LFR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1441930:Z042 RS19740
gene id: 1441930:Z042_RS19740
uniprot id: W0LHD2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1441930:Z042 RS23455
gene id: 1441930:Z042_RS23455
uniprot id: W0LGN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1441930:Z042 RS05050
gene id: 1441930:Z042_RS05050
uniprot id: W0L8E3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS09660
gene id: 1441930:Z042_RS09660
uniprot id: W0LB94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS23500
gene id: 1441930:Z042_RS23500
uniprot id: W0LBL8
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS11175
gene id: 1441930:Z042_RS11175
uniprot id: W0L5A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1441930:Z042 RS18730
gene id: 1441930:Z042_RS18730
uniprot id: W0LDR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1441930:Z042 RS21005
gene id: 1441930:Z042_RS21005
uniprot id: W0LCK5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1441930:Z042 RS08140
gene id: 1441930:Z042_RS08140
uniprot id: W0LC27
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS19165
gene id: 1441930:Z042_RS19165
uniprot id: W0LIW1
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

1441930:Z042 RS19105
gene id: 1441930:Z042_RS19105
uniprot id: W0LKM6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1441930:Z042 RS23855
gene id: 1441930:Z042_RS23855
uniprot id: W0LFK4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1441930:Z042 RS07645
gene id: 1441930:Z042_RS07645
uniprot id: A0A0D4ZY20
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1441930:Z042 RS05490
gene id: 1441930:Z042_RS05490
uniprot id: W0L8G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1441930:Z042 RS04185
gene id: 1441930:Z042_RS04185
uniprot id: W0L911
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1441930:Z042 RS19135
gene id: 1441930:Z042_RS19135
uniprot id: W0LDY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS04785
gene id: 1441930:Z042_RS04785
uniprot id: W0LCX6
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1441930:Z042 RS09160
gene id: 1441930:Z042_RS09160
uniprot id: W0L6B1
names: Similarity
messages: Belongs to the UPF0149 family.

1441930:Z042 RS00345
gene id: 1441930:Z042_RS00345
uniprot id: W0LB21
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

1441930:Z042 RS09965
gene id: 1441930:Z042_RS09965
uniprot id: W0LA89
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1441930:Z042 RS21635
gene id: 1441930:Z042_RS21635
uniprot id: W0LHL9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1441930:Z042 RS07050
gene id: 1441930:Z042_RS07050
uniprot id: W0LCN3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1441930:Z042 RS10825
gene id: 1441930:Z042_RS10825
uniprot id: W0L5P2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS12280
gene id: 1441930:Z042_RS12280
uniprot id: W0L9U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1441930:Z042 RS16510
gene id: 1441930:Z042_RS16510
uniprot id: A0A0D4ZYH9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS16125
gene id: 1441930:Z042_RS16125
uniprot id: W0LKF8
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS12465
gene id: 1441930:Z042_RS12465
uniprot id: W0L8M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1441930:Z042 RS13990
gene id: 1441930:Z042_RS13990
uniprot id: W0L937
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1441930:Z042 RS03760
gene id: 1441930:Z042_RS03760
uniprot id: W0L915
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1441930:Z042 RS07440
gene id: 1441930:Z042_RS07440
uniprot id: W0LCF1
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

1441930:Z042 RS12780
gene id: 1441930:Z042_RS12780
uniprot id: W0L9J0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1441930:Z042 RS11010
gene id: 1441930:Z042_RS11010
uniprot id: W0L5D2
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS23035
gene id: 1441930:Z042_RS23035
uniprot id: W0LFP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1441930:Z042 RS20525
gene id: 1441930:Z042_RS20525
uniprot id: W0LCU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1441930:Z042 RS12790
gene id: 1441930:Z042_RS12790
uniprot id: W0L4I3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS04315
gene id: 1441930:Z042_RS04315
uniprot id: W0LD57
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS21390
gene id: 1441930:Z042_RS21390
uniprot id: W0LCQ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS13335
gene id: 1441930:Z042_RS13335
uniprot id: A0A0D4ZYE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS09260
gene id: 1441930:Z042_RS09260
uniprot id: W0LBH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-modifying YgfZ family.
messages: Cytoplasm
messages: Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.

1441930:Z042 RS03170
gene id: 1441930:Z042_RS03170
uniprot id: W0LDG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
messages: Cell inner membrane
messages: Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
messages: Membrane
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

1441930:Z042 RS11710
gene id: 1441930:Z042_RS11710
uniprot id: W0L9F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1441930:Z042 RS09645
gene id: 1441930:Z042_RS09645
uniprot id: W0L618
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1441930:Z042 RS09065
gene id: 1441930:Z042_RS09065
uniprot id: W0LAS7
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

1441930:Z042 RS21835
gene id: 1441930:Z042_RS21835
uniprot id: W0LCH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1441930:Z042 RS03275
gene id: 1441930:Z042_RS03275
uniprot id: W0LDE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS15600
gene id: 1441930:Z042_RS15600
uniprot id: W0L3D0
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1441930:Z042 RS14575
gene id: 1441930:Z042_RS14575
uniprot id: W0L7R6
names: Similarity
messages: Belongs to the IucA/IucC family.

1441930:Z042 RS06905
gene id: 1441930:Z042_RS06905
uniprot id: W0LBV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1441930:Z042 RS11295
gene id: 1441930:Z042_RS11295
uniprot id: W0L9K5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

1441930:Z042 RS19855
gene id: 1441930:Z042_RS19855
uniprot id: W0LD65
names: Similarity
messages: Belongs to the hyi family.

1441930:Z042 RS07765
gene id: 1441930:Z042_RS07765
uniprot id: W0L775
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS11495
gene id: 1441930:Z042_RS11495
uniprot id: W0L973
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1441930:Z042 RS02655
gene id: 1441930:Z042_RS02655
uniprot id: W0LE08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

1441930:Z042 RS03090
gene id: 1441930:Z042_RS03090
uniprot id: W0LER9
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1441930:Z042 RS08585
gene id: 1441930:Z042_RS08585
uniprot id: W0L6V9
names: Similarity
messages: Belongs to the GSP E family.

1441930:Z042 RS21485
gene id: 1441930:Z042_RS21485
uniprot id: W0LGU5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1441930:Z042 RS06830
gene id: 1441930:Z042_RS06830
uniprot id: W0LBW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1441930:Z042 RS06065
gene id: 1441930:Z042_RS06065
uniprot id: W0LD85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1441930:Z042 RS23565
gene id: 1441930:Z042_RS23565
uniprot id: W0LB83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

1441930:Z042 RS22330
gene id: 1441930:Z042_RS22330
uniprot id: W0LGB5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1441930:Z042 RS06005
gene id: 1441930:Z042_RS06005
uniprot id: W0LCE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1441930:Z042 RS21135
gene id: 1441930:Z042_RS21135
uniprot id: W0LGN6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1441930:Z042 RS06095
gene id: 1441930:Z042_RS06095
uniprot id: W0LBZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1441930:Z042 RS09540
gene id: 1441930:Z042_RS09540
uniprot id: W0LA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS23795
gene id: 1441930:Z042_RS23795
uniprot id: W0LFL2
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS05910
gene id: 1441930:Z042_RS05910
uniprot id: W0L887
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
messages: Cell inner membrane
messages: Interacts with KefB.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.

1441930:Z042 RS15125
gene id: 1441930:Z042_RS15125
uniprot id: W0L8H7
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

1441930:Z042 RS11160
gene id: 1441930:Z042_RS11160
uniprot id: W0L5I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1441930:Z042 RS21430
gene id: 1441930:Z042_RS21430
uniprot id: W0LCC1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS23865
gene id: 1441930:Z042_RS23865
uniprot id: W0LGG6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1441930:Z042 RS20320
gene id: 1441930:Z042_RS20320
uniprot id: W0LD88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1441930:Z042 RS19400
gene id: 1441930:Z042_RS19400
uniprot id: W0LDT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1441930:Z042 RS16175
gene id: 1441930:Z042_RS16175
uniprot id: W0LFF6
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.
messages: Monomer.

1441930:Z042 RS06210
gene id: 1441930:Z042_RS06210
uniprot id: W0L834
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1441930:Z042 RS21875
gene id: 1441930:Z042_RS21875
uniprot id: W0LC56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1441930:Z042 RS21715
gene id: 1441930:Z042_RS21715
uniprot id: W0LHK8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1441930:Z042 RS04295
gene id: 1441930:Z042_RS04295
uniprot id: W0LCV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1441930:Z042 RS18895
gene id: 1441930:Z042_RS18895
uniprot id: W0LHZ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1441930:Z042 RS09730
gene id: 1441930:Z042_RS09730
uniprot id: W0LA26
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

1441930:Z042 RS18225
gene id: 1441930:Z042_RS18225
uniprot id: W0LI19
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1441930:Z042 RS21545
gene id: 1441930:Z042_RS21545
uniprot id: W0LGT5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1441930:Z042 RS18310
gene id: 1441930:Z042_RS18310
uniprot id: W0LI99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS12545
gene id: 1441930:Z042_RS12545
uniprot id: W0L4M8
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1441930:Z042 RS09870
gene id: 1441930:Z042_RS09870
uniprot id: W0L654
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1441930:Z042 RS06405
gene id: 1441930:Z042_RS06405
uniprot id: W0L7X4
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1441930:Z042 RS15575
gene id: 1441930:Z042_RS15575
uniprot id: W0L3D5
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS23135
gene id: 1441930:Z042_RS23135
uniprot id: W0LGV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1441930:Z042 RS04970
gene id: 1441930:Z042_RS04970
uniprot id: W0L8F4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1441930:Z042 RS05845
gene id: 1441930:Z042_RS05845
uniprot id: W0LC39
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1441930:Z042 RS09940
gene id: 1441930:Z042_RS09940
uniprot id: W0LA94
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1441930:Z042 RS14720
gene id: 1441930:Z042_RS14720
uniprot id: W0L3R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS08545
gene id: 1441930:Z042_RS08545
uniprot id: W0LAQ0
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1441930:Z042 RS18450
gene id: 1441930:Z042_RS18450
uniprot id: W0LHY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1441930:Z042 RS12760
gene id: 1441930:Z042_RS12760
uniprot id: W0L8H0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1441930:Z042 RS12425
gene id: 1441930:Z042_RS12425
uniprot id: W0L902
names: Similarity
messages: Belongs to the UPF0304 family.

1441930:Z042 RS23975
gene id: 1441930:Z042_RS23975
uniprot id: W0LFI7
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS08970
gene id: 1441930:Z042_RS08970
uniprot id: W0LAH8
names: Similarity
messages: Belongs to the carbamate kinase family.

1441930:Z042 RS08675
gene id: 1441930:Z042_RS08675
uniprot id: W0LBV6
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1441930:Z042 RS09630
gene id: 1441930:Z042_RS09630
uniprot id: A0A0D4ZYE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
messages: Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS05825
gene id: 1441930:Z042_RS05825
uniprot id: W0L812
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1441930:Z042 RS20340
gene id: 1441930:Z042_RS20340
uniprot id: W0LHB8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1441930:Z042 RS18425
gene id: 1441930:Z042_RS18425
uniprot id: W0LHY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1441930:Z042 RS13910
gene id: 1441930:Z042_RS13910
uniprot id: W0L493
names: Similarity
messages: Belongs to the HupJ family.

1441930:Z042 RS23125
gene id: 1441930:Z042_RS23125
uniprot id: W0LFY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS11440
gene id: 1441930:Z042_RS11440
uniprot id: W0L979
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1441930:Z042 RS11860
gene id: 1441930:Z042_RS11860
uniprot id: W0L550
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1441930:Z042 RS06290
gene id: 1441930:Z042_RS06290
uniprot id: W0L819
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Part of an electron transfer system.

1441930:Z042 RS12220
gene id: 1441930:Z042_RS12220
uniprot id: W0L4Z0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS21695
gene id: 1441930:Z042_RS21695
uniprot id: W0LGF0
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

1441930:Z042 RS20600
gene id: 1441930:Z042_RS20600
uniprot id: W0LCS7
names: Similarity
messages: Belongs to the ModE family.

1441930:Z042 RS18550
gene id: 1441930:Z042_RS18550
uniprot id: W0LHW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1441930:Z042 RS23180
gene id: 1441930:Z042_RS23180
uniprot id: W0LGU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS16215
gene id: 1441930:Z042_RS16215
uniprot id: A0A0D4ZYK1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS14470
gene id: 1441930:Z042_RS14470
uniprot id: W0L3U9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1441930:Z042 RS09740
gene id: 1441930:Z042_RS09740
uniprot id: W0LAD5
names: Similarity
messages: Belongs to the SufE family.

1441930:Z042 RS20110
gene id: 1441930:Z042_RS20110
uniprot id: W0LD21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1441930:Z042 RS06565
gene id: 1441930:Z042_RS06565
uniprot id: W0LCX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1441930:Z042 RS16925
gene id: 1441930:Z042_RS16925
uniprot id: W0LIN9
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS06720
gene id: 1441930:Z042_RS06720
uniprot id: W0LBM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

1441930:Z042 RS07365
gene id: 1441930:Z042_RS07365
uniprot id: W0LCG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1441930:Z042 RS05740
gene id: 1441930:Z042_RS05740
uniprot id: W0LDD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS20945
gene id: 1441930:Z042_RS20945
uniprot id: W0LGR9
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer; trimer of disulfide-linked dimers.

1441930:Z042 RS19000
gene id: 1441930:Z042_RS19000
uniprot id: W0LHY3
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS01580
gene id: 1441930:Z042_RS01580
uniprot id: W0LE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1441930:Z042 RS19810
gene id: 1441930:Z042_RS19810
uniprot id: W0LIG7
names: Similarity
messages: Belongs to the GST superfamily.

1441930:Z042 RS11325
gene id: 1441930:Z042_RS11325
uniprot id: W0L9K3
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS11890
gene id: 1441930:Z042_RS11890
uniprot id: W0LA13
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS04080
gene id: 1441930:Z042_RS04080
uniprot id: W0LE69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1441930:Z042 RS15425
gene id: 1441930:Z042_RS15425
uniprot id: W0L3B0
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1441930:Z042 RS24290
gene id: 1441930:Z042_RS24290
uniprot id: W0LAW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1441930:Z042 RS07760
gene id: 1441930:Z042_RS07760
uniprot id: W0LBF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1441930:Z042 RS03930
gene id: 1441930:Z042_RS03930
uniprot id: W0LEA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1441930:Z042 RS22585
gene id: 1441930:Z042_RS22585
uniprot id: W0LC14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZraP family.
messages: Binds zinc. Could be an important component of the zinc-balancing mechanism.
messages: Periplasm

1441930:Z042 RS20640
gene id: 1441930:Z042_RS20640
uniprot id: W0LD33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1441930:Z042 RS02895
gene id: 1441930:Z042_RS02895
uniprot id: W0LDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcrB family.
messages: Cell membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered.

1441930:Z042 RS06820
gene id: 1441930:Z042_RS06820
uniprot id: W0LBK0
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1441930:Z042 RS21755
gene id: 1441930:Z042_RS21755
uniprot id: W0LGP9
names: Similarity
messages: Belongs to the BolA/IbaG family.

1441930:Z042 RS16705
gene id: 1441930:Z042_RS16705
uniprot id: W0LK44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

1441930:Z042 RS20165
gene id: 1441930:Z042_RS20165
uniprot id: W0LD11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS15815
gene id: 1441930:Z042_RS15815
uniprot id: W0LJB3
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1441930:Z042 RS16885
gene id: 1441930:Z042_RS16885
uniprot id: W0LIZ0
names: Similarity
messages: Belongs to the fructosamine kinase family.

1441930:Z042 RS21325
gene id: 1441930:Z042_RS21325
uniprot id: W0LHQ7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1441930:Z042 RS03250
gene id: 1441930:Z042_RS03250
uniprot id: W0L9C4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

1441930:Z042 RS06700
gene id: 1441930:Z042_RS06700
uniprot id: W0LBZ2
names: Similarity
messages: Belongs to the barstar family.

1441930:Z042 RS20445
gene id: 1441930:Z042_RS20445
uniprot id: W0LHA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cdh family.
messages: Membrane

1441930:Z042 RS23475
gene id: 1441930:Z042_RS23475
uniprot id: W0LBM2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS00860
gene id: 1441930:Z042_RS00860
uniprot id: W0LFU9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1441930:Z042 RS11460
gene id: 1441930:Z042_RS11460
uniprot id: W0LAC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS07200
gene id: 1441930:Z042_RS07200
uniprot id: W0LBQ3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1441930:Z042 RS06040
gene id: 1441930:Z042_RS06040
uniprot id: W0LD90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1441930:Z042 RS09280
gene id: 1441930:Z042_RS09280
uniprot id: W0L6G0
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS04420
gene id: 1441930:Z042_RS04420
uniprot id: W0L8X8
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1441930:Z042 RS12235
gene id: 1441930:Z042_RS12235
uniprot id: A0A0D4ZY23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS04780
gene id: 1441930:Z042_RS04780
uniprot id: W0L8I3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1441930:Z042 RS05545
gene id: 1441930:Z042_RS05545
uniprot id: W0L8F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS17190
gene id: 1441930:Z042_RS17190
uniprot id: W0LIT9
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1441930:Z042 RS02650
gene id: 1441930:Z042_RS02650
uniprot id: W0L9L2
names: Similarity
messages: Belongs to the peptidase S51 family.

1441930:Z042 RS11630
gene id: 1441930:Z042_RS11630
uniprot id: W0L9F8
names: Similarity
messages: Belongs to the isochorismate synthase family.

1441930:Z042 RS04635
gene id: 1441930:Z042_RS04635
uniprot id: W0L8T7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Activates expression of the rhaSR operon in response to L-rhamnose.
messages: Binds DNA as a dimer.
messages: Cytoplasm

1441930:Z042 RS04170
gene id: 1441930:Z042_RS04170
uniprot id: W0LCX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1441930:Z042 RS18470
gene id: 1441930:Z042_RS18470
uniprot id: W0LJ74
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1441930:Z042 RS21625
gene id: 1441930:Z042_RS21625
uniprot id: W0LGS2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1441930:Z042 RS12875
gene id: 1441930:Z042_RS12875
uniprot id: W0L4G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1441930:Z042 RS18975
gene id: 1441930:Z042_RS18975
uniprot id: W0LHY7
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1441930:Z042 RS04720
gene id: 1441930:Z042_RS04720
uniprot id: W0LDU4
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1441930:Z042 RS14640
gene id: 1441930:Z042_RS14640
uniprot id: W0L814
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1441930:Z042 RS10630
gene id: 1441930:Z042_RS10630
uniprot id: W0LAR2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

1441930:Z042 RS05035
gene id: 1441930:Z042_RS05035
uniprot id: W0L8M9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS15295
gene id: 1441930:Z042_RS15295
uniprot id: W0L3I9
names: Similarity
messages: Belongs to the Dps family.

1441930:Z042 RS12255
gene id: 1441930:Z042_RS12255
uniprot id: W0L9U5
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS07025
gene id: 1441930:Z042_RS07025
uniprot id: W0LCN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS06550
gene id: 1441930:Z042_RS06550
uniprot id: W0L7L9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1441930:Z042 RS15800
gene id: 1441930:Z042_RS15800
uniprot id: A0A0D4ZXK8
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS08560
gene id: 1441930:Z042_RS08560
uniprot id: W0L6W3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1441930:Z042 RS04030
gene id: 1441930:Z042_RS04030
uniprot id: W0LE81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS13490
gene id: 1441930:Z042_RS13490
uniprot id: W0L853
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1441930:Z042 RS06480
gene id: 1441930:Z042_RS06480
uniprot id: W0L7V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

1441930:Z042 RS15495
gene id: 1441930:Z042_RS15495
uniprot id: W0L8A1
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1441930:Z042 RS06295
gene id: 1441930:Z042_RS06295
uniprot id: W0LD48
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS04835
gene id: 1441930:Z042_RS04835
uniprot id: W0L8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1441930:Z042 RS21850
gene id: 1441930:Z042_RS21850
uniprot id: W0LC61
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1441930:Z042 RS14820
gene id: 1441930:Z042_RS14820
uniprot id: W0L7K3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS12930
gene id: 1441930:Z042_RS12930
uniprot id: W0L8R2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS01015
gene id: 1441930:Z042_RS01015
uniprot id: W0LAM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1441930:Z042 RS03870
gene id: 1441930:Z042_RS03870
uniprot id: W0L968
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1441930:Z042 RS17215
gene id: 1441930:Z042_RS17215
uniprot id: W0LIT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1441930:Z042 RS05785
gene id: 1441930:Z042_RS05785
uniprot id: W0L8B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1441930:Z042 RS04555
gene id: 1441930:Z042_RS04555
uniprot id: W0L8V2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1441930:Z042 RS11425
gene id: 1441930:Z042_RS11425
uniprot id: W0L9I4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1441930:Z042 RS11080
gene id: 1441930:Z042_RS11080
uniprot id: W0L9C9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1441930:Z042 RS01110
gene id: 1441930:Z042_RS01110
uniprot id: W0LEQ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1441930:Z042 RS12800
gene id: 1441930:Z042_RS12800
uniprot id: W0L4N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS18845
gene id: 1441930:Z042_RS18845
uniprot id: W0LJ12
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

1441930:Z042 RS23060
gene id: 1441930:Z042_RS23060
uniprot id: W0LFN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1441930:Z042 RS04050
gene id: 1441930:Z042_RS04050
uniprot id: W0L935
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS11520
gene id: 1441930:Z042_RS11520
uniprot id: W0L967
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS13535
gene id: 1441930:Z042_RS13535
uniprot id: W0L993
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1441930:Z042 RS11025
gene id: 1441930:Z042_RS11025
uniprot id: W0LAJ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC.

1441930:Z042 RS04155
gene id: 1441930:Z042_RS04155
uniprot id: W0LD83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1441930:Z042 RS17050
gene id: 1441930:Z042_RS17050
uniprot id: W0LIW0
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS18325
gene id: 1441930:Z042_RS18325
uniprot id: W0LI01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.
messages: Homodimer.

1441930:Z042 RS18785
gene id: 1441930:Z042_RS18785
uniprot id: W0LI11
names: Similarity
messages: Belongs to the YkuD family.

1441930:Z042 RS07090
gene id: 1441930:Z042_RS07090
uniprot id: W0LBS4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1441930:Z042 RS19975
gene id: 1441930:Z042_RS19975
uniprot id: W0LDE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1441930:Z042 RS04135
gene id: 1441930:Z042_RS04135
uniprot id: W0L921
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1441930:Z042 RS16700
gene id: 1441930:Z042_RS16700
uniprot id: W0LF35
names: Similarity
messages: Belongs to the peptidase C40 family.

1441930:Z042 RS22230
gene id: 1441930:Z042_RS22230
uniprot id: W0LGD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1441930:Z042 RS03185
gene id: 1441930:Z042_RS03185
uniprot id: W0L9N2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1441930:Z042 RS19065
gene id: 1441930:Z042_RS19065
uniprot id: W0LHP2
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

1441930:Z042 RS16640
gene id: 1441930:Z042_RS16640
uniprot id: W0LJ66
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1441930:Z042 RS21600
gene id: 1441930:Z042_RS21600
uniprot id: W0LGS5
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS12420
gene id: 1441930:Z042_RS12420
uniprot id: W0L4P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1441930:Z042 RS19915
gene id: 1441930:Z042_RS19915
uniprot id: W0LHH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1441930:Z042 RS10670
gene id: 1441930:Z042_RS10670
uniprot id: W0L9W8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1441930:Z042 RS02160
gene id: 1441930:Z042_RS02160
uniprot id: W0LDX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS19715
gene id: 1441930:Z042_RS19715
uniprot id: W0LHD6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Binds 1 sodium ion per monomer.
messages: Binds 2 magnesium ions per monomer.
messages: Homotetramer.

1441930:Z042 RS15155
gene id: 1441930:Z042_RS15155
uniprot id: W0L7D9
names: Similarity
messages: Belongs to the peptidase S49 family.

1441930:Z042 RS20725
gene id: 1441930:Z042_RS20725
uniprot id: W0LD20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS21330
gene id: 1441930:Z042_RS21330
uniprot id: W0LGK2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1441930:Z042 RS23460
gene id: 1441930:Z042_RS23460
uniprot id: W0LFF7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1441930:Z042 RS01250
gene id: 1441930:Z042_RS01250
uniprot id: W0LED1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS23665
gene id: 1441930:Z042_RS23665
uniprot id: W0LFB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1441930:Z042 RS19995
gene id: 1441930:Z042_RS19995
uniprot id: W0LHG3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

1441930:Z042 RS08700
gene id: 1441930:Z042_RS08700
uniprot id: W0LBV1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1441930:Z042 RS18235
gene id: 1441930:Z042_RS18235
uniprot id: W0LIB3
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS07650
gene id: 1441930:Z042_RS07650
uniprot id: W0LB41
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS22435
gene id: 1441930:Z042_RS22435
uniprot id: W0LG99
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1441930:Z042 RS10490
gene id: 1441930:Z042_RS10490
uniprot id: W0L5M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1441930:Z042 RS18345
gene id: 1441930:Z042_RS18345
uniprot id: W0LJ98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1441930:Z042 RS08920
gene id: 1441930:Z042_RS08920
uniprot id: W0LAV0
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS05280
gene id: 1441930:Z042_RS05280
uniprot id: W0LCC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1441930:Z042 RS14310
gene id: 1441930:Z042_RS14310
uniprot id: W0L862
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS05955
gene id: 1441930:Z042_RS05955
uniprot id: W0LCF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrH/TusB family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

1441930:Z042 RS22670
gene id: 1441930:Z042_RS22670
uniprot id: W0LFW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS08110
gene id: 1441930:Z042_RS08110
uniprot id: W0L722
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS23415
gene id: 1441930:Z042_RS23415
uniprot id: W0LBB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Cell inner membrane
messages: Involved in succinate export with YjjP. Both proteins are required for export.
messages: Membrane
messages: The transporter is composed of YjjB and YjjP.

1441930:Z042 RS07265
gene id: 1441930:Z042_RS07265
uniprot id: W0LBB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1441930:Z042 RS09865
gene id: 1441930:Z042_RS09865
uniprot id: W0LAA9
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1441930:Z042 RS05800
gene id: 1441930:Z042_RS05800
uniprot id: W0L818
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1441930:Z042 RS12495
gene id: 1441930:Z042_RS12495
uniprot id: W0L4N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1441930:Z042 RS10475
gene id: 1441930:Z042_RS10475
uniprot id: W0L5V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1441930:Z042 RS04350
gene id: 1441930:Z042_RS04350
uniprot id: W0LCU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS05780
gene id: 1441930:Z042_RS05780
uniprot id: W0LCI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS18735
gene id: 1441930:Z042_RS18735
uniprot id: W0LI20
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.
messages: FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.
messages: Homotetramer.

1441930:Z042 RS05895
gene id: 1441930:Z042_RS05895
uniprot id: W0LC30
names: Similarity
messages: Belongs to the PhzF family.

1441930:Z042 RS03910
gene id: 1441930:Z042_RS03910
uniprot id: W0L8Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1441930:Z042 RS10010
gene id: 1441930:Z042_RS10010
uniprot id: W0L5U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

1441930:Z042 RS16345
gene id: 1441930:Z042_RS16345
uniprot id: W0LJ32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS11030
gene id: 1441930:Z042_RS11030
uniprot id: W0L9D5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC.

1441930:Z042 RS22205
gene id: 1441930:Z042_RS22205
uniprot id: W0LGF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1441930:Z042 RS05875
gene id: 1441930:Z042_RS05875
uniprot id: W0L804
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1441930:Z042 RS06875
gene id: 1441930:Z042_RS06875
uniprot id: W0L7G2
names: Similarity
messages: Belongs to the BolA/IbaG family.

1441930:Z042 RS21595
gene id: 1441930:Z042_RS21595
uniprot id: W0LC95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS08840
gene id: 1441930:Z042_RS08840
uniprot id: W0L6J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1441930:Z042 RS15215
gene id: 1441930:Z042_RS15215
uniprot id: W0L8F8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

1441930:Z042 RS03195
gene id: 1441930:Z042_RS03195
uniprot id: W0LDF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

1441930:Z042 RS16440
gene id: 1441930:Z042_RS16440
uniprot id: W0LKB4
names: Similarity
messages: Belongs to the GST superfamily.

1441930:Z042 RS22500
gene id: 1441930:Z042_RS22500
uniprot id: W0LFZ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1441930:Z042 RS05200
gene id: 1441930:Z042_RS05200
uniprot id: W0LCR0
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS22075
gene id: 1441930:Z042_RS22075
uniprot id: W0LC28
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS11270
gene id: 1441930:Z042_RS11270
uniprot id: W0L9L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1441930:Z042 RS23535
gene id: 1441930:Z042_RS23535
uniprot id: W0LFE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS23380
gene id: 1441930:Z042_RS23380
uniprot id: W0LGQ4
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1441930:Z042 RS16940
gene id: 1441930:Z042_RS16940
uniprot id: W0LEY9
names: Similarity
messages: Belongs to the peptidase S41A family.

1441930:Z042 RS02235
gene id: 1441930:Z042_RS02235
uniprot id: W0LDV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1441930:Z042 RS22445
gene id: 1441930:Z042_RS22445
uniprot id: W0LH84
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1441930:Z042 RS05915
gene id: 1441930:Z042_RS05915
uniprot id: W0LDB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

1441930:Z042 RS04165
gene id: 1441930:Z042_RS04165
uniprot id: W0LE47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1441930:Z042 RS07355
gene id: 1441930:Z042_RS07355
uniprot id: W0LBM8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1441930:Z042 RS15710
gene id: 1441930:Z042_RS15710
uniprot id: W0LKM4
names: Similarity
messages: Belongs to the VgrG protein family.

1441930:Z042 RS19125
gene id: 1441930:Z042_RS19125
uniprot id: W0LDK8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

1441930:Z042 RS19530
gene id: 1441930:Z042_RS19530
uniprot id: W0LDC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS18560
gene id: 1441930:Z042_RS18560
uniprot id: W0LI53
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

1441930:Z042 RS21415
gene id: 1441930:Z042_RS21415
uniprot id: W0LCQ4
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of L-fuculose.

1441930:Z042 RS18440
gene id: 1441930:Z042_RS18440
uniprot id: W0LE97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1441930:Z042 RS15780
gene id: 1441930:Z042_RS15780
uniprot id: W0LF76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1441930:Z042 RS21990
gene id: 1441930:Z042_RS21990
uniprot id: W0LGA5
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS20195
gene id: 1441930:Z042_RS20195
uniprot id: W0LH65
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1441930:Z042 RS02645
gene id: 1441930:Z042_RS02645
uniprot id: W0LDP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1441930:Z042 RS24170
gene id: 1441930:Z042_RS24170
uniprot id: W0LGC0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1441930:Z042 RS03245
gene id: 1441930:Z042_RS03245
uniprot id: W0LDF2
names: Similarity
messages: Belongs to the peptidase M16 family.

1441930:Z042 RS01120
gene id: 1441930:Z042_RS01120
uniprot id: W0LFP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

1441930:Z042 RS19545
gene id: 1441930:Z042_RS19545
uniprot id: W0LIM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS00745
gene id: 1441930:Z042_RS00745
uniprot id: W0LFW9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1441930:Z042 RS14525
gene id: 1441930:Z042_RS14525
uniprot id: W0L830
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1441930:Z042 RS04390
gene id: 1441930:Z042_RS04390
uniprot id: W0LD42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1441930:Z042 RS07610
gene id: 1441930:Z042_RS07610
uniprot id: W0LBI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1441930:Z042 RS19905
gene id: 1441930:Z042_RS19905
uniprot id: W0LHA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS12525
gene id: 1441930:Z042_RS12525
uniprot id: W0L8Y5
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

1441930:Z042 RS14415
gene id: 1441930:Z042_RS14415
uniprot id: W0L850
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1441930:Z042 RS07110
gene id: 1441930:Z042_RS07110
uniprot id: W0L7B5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1441930:Z042 RS21800
gene id: 1441930:Z042_RS21800
uniprot id: W0LC66
names: Similarity
messages: Belongs to the UPF0234 family.

1441930:Z042 RS20510
gene id: 1441930:Z042_RS20510
uniprot id: W0LD53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1441930:Z042 RS14990
gene id: 1441930:Z042_RS14990
uniprot id: W0L3J3
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

1441930:Z042 RS16190
gene id: 1441930:Z042_RS16190
uniprot id: W0LF12
names: Similarity
messages: Belongs to the UPF0482 family.

1441930:Z042 RS04410
gene id: 1441930:Z042_RS04410
uniprot id: W0L8Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1441930:Z042 RS16095
gene id: 1441930:Z042_RS16095
uniprot id: W0LKG2
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

1441930:Z042 RS18375
gene id: 1441930:Z042_RS18375
uniprot id: W0LHZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1441930:Z042 RS15465
gene id: 1441930:Z042_RS15465
uniprot id: W0L3F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1441930:Z042 RS03015
gene id: 1441930:Z042_RS03015
uniprot id: W0L9F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1441930:Z042 RS11940
gene id: 1441930:Z042_RS11940
uniprot id: W0LA02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Amino-acid racemase able to utilize a broad range of substrates.
messages: Belongs to the alanine racemase family. Bsr subfamily.
messages: Periplasm

1441930:Z042 RS13880
gene id: 1441930:Z042_RS13880
uniprot id: W0L8D2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1441930:Z042 RS05015
gene id: 1441930:Z042_RS05015
uniprot id: W0LDQ5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1441930:Z042 RS10710
gene id: 1441930:Z042_RS10710
uniprot id: W0L9I5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS13405
gene id: 1441930:Z042_RS13405
uniprot id: W0L497
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS15235
gene id: 1441930:Z042_RS15235
uniprot id: W0L7Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1441930:Z042 RS05620
gene id: 1441930:Z042_RS05620
uniprot id: W0LCK3
names: Function
names: Similarity
messages: Belongs to the FeoC family.
messages: May function as a transcriptional regulator that controls feoABC expression.

1441930:Z042 RS10800
gene id: 1441930:Z042_RS10800
uniprot id: W0L5P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1441930:Z042 RS10570
gene id: 1441930:Z042_RS10570
uniprot id: W0L9Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1441930:Z042 RS15585
gene id: 1441930:Z042_RS15585
uniprot id: W0L766
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1441930:Z042 RS20190
gene id: 1441930:Z042_RS20190
uniprot id: W0LI91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS20210
gene id: 1441930:Z042_RS20210
uniprot id: W0LDA4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1441930:Z042 RS11755
gene id: 1441930:Z042_RS11755
uniprot id: W0LA81
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1441930:Z042 RS12590
gene id: 1441930:Z042_RS12590
uniprot id: W0L8J9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1441930:Z042 RS18915
gene id: 1441930:Z042_RS18915
uniprot id: W0LDP0
names: Similarity
messages: Belongs to the asparaginase 1 family.

1441930:Z042 RS19415
gene id: 1441930:Z042_RS19415
uniprot id: W0LDG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1441930:Z042 RS09955
gene id: 1441930:Z042_RS09955
uniprot id: W0L9X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1441930:Z042 RS18040
gene id: 1441930:Z042_RS18040
uniprot id: W0LE52
names: Subcellular Location Annotation
messages: Cytoplasm

1441930:Z042 RS18590
gene id: 1441930:Z042_RS18590
uniprot id: W0LE66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

1441930:Z042 RS13085
gene id: 1441930:Z042_RS13085
uniprot id: W0L4J8
names: Similarity
messages: Belongs to the Gfa family.

1441930:Z042 RS18965
gene id: 1441930:Z042_RS18965
uniprot id: W0LHQ4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1441930:Z042 RS22920
gene id: 1441930:Z042_RS22920
uniprot id: W0LGZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

1441930:Z042 RS02915
gene id: 1441930:Z042_RS02915
uniprot id: W0LEU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

1441930:Z042 RS07750
gene id: 1441930:Z042_RS07750
uniprot id: W0LB17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

1441930:Z042 RS23160
gene id: 1441930:Z042_RS23160
uniprot id: W0LFL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

1441930:Z042 RS20635
gene id: 1441930:Z042_RS20635
uniprot id: W0LH73
names: Similarity
messages: Belongs to the aldose epimerase family.

1441930:Z042 RS15500
gene id: 1441930:Z042_RS15500
uniprot id: W0L779
names: Subcellular Location Annotation
messages: Cytoplasm

1441930:Z042 RS21910
gene id: 1441930:Z042_RS21910
uniprot id: W0LLL6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS21890
gene id: 1441930:Z042_RS21890
uniprot id: W0LHI4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1441930:Z042 RS07145
gene id: 1441930:Z042_RS07145
uniprot id: W0L7I4
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1441930:Z042 RS00975
gene id: 1441930:Z042_RS00975
uniprot id: W0LEJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS23195
gene id: 1441930:Z042_RS23195
uniprot id: W0LFX0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1441930:Z042 RS04880
gene id: 1441930:Z042_RS04880
uniprot id: W0LFW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
messages: Cell outer membrane
messages: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1441930:Z042 RS23100
gene id: 1441930:Z042_RS23100
uniprot id: W0LKS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1441930:Z042 RS11155
gene id: 1441930:Z042_RS11155
uniprot id: W0L9M9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1441930:Z042 RS21110
gene id: 1441930:Z042_RS21110
uniprot id: W0LGP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1441930:Z042 RS18715
gene id: 1441930:Z042_RS18715
uniprot id: W0LE46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

1441930:Z042 RS01050
gene id: 1441930:Z042_RS01050
uniprot id: W0LEH6
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS12720
gene id: 1441930:Z042_RS12720
uniprot id: W0L8U9
names: Similarity
messages: Belongs to the peptidase C40 family.

1441930:Z042 RS05950
gene id: 1441930:Z042_RS05950
uniprot id: W0L7Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrF/TusC family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

1441930:Z042 RS22850
gene id: 1441930:Z042_RS22850
uniprot id: W0LBM1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1441930:Z042 RS09440
gene id: 1441930:Z042_RS09440
uniprot id: W0LAI6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1441930:Z042 RS04755
gene id: 1441930:Z042_RS04755
uniprot id: W0L8I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsN family.
messages: Cell inner membrane
messages: Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
messages: Interacts with FtsA via its N-terminal cytoplasmic domain.

1441930:Z042 RS19550
gene id: 1441930:Z042_RS19550
uniprot id: A0A0D4ZXM6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1441930:Z042 RS23525
gene id: 1441930:Z042_RS23525
uniprot id: W0LBL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1441930:Z042 RS14535
gene id: 1441930:Z042_RS14535
uniprot id: W0L8W3
names: Similarity
messages: Belongs to the UPF0303 family.

1441930:Z042 RS20730
gene id: 1441930:Z042_RS20730
uniprot id: W0LHZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1441930:Z042 RS01435
gene id: 1441930:Z042_RS01435
uniprot id: W0LAF3
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS19675
gene id: 1441930:Z042_RS19675
uniprot id: W0LHK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1441930:Z042 RS20015
gene id: 1441930:Z042_RS20015
uniprot id: W0LD39
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS12320
gene id: 1441930:Z042_RS12320
uniprot id: W0L4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS22995
gene id: 1441930:Z042_RS22995
uniprot id: W0LBU5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
messages: Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM.

1441930:Z042 RS10575
gene id: 1441930:Z042_RS10575
uniprot id: W0L5T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1441930:Z042 RS21140
gene id: 1441930:Z042_RS21140
uniprot id: W0LCH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1441930:Z042 RS12740
gene id: 1441930:Z042_RS12740
uniprot id: W0L4J3
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1441930:Z042 RS22780
gene id: 1441930:Z042_RS22780
uniprot id: W0LLL0
names: Similarity
messages: Belongs to the peptidase C40 family.

1441930:Z042 RS15260
gene id: 1441930:Z042_RS15260
uniprot id: W0L3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS18570
gene id: 1441930:Z042_RS18570
uniprot id: W0LJ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1441930:Z042 RS06085
gene id: 1441930:Z042_RS06085
uniprot id: W0L854
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1441930:Z042 RS09475
gene id: 1441930:Z042_RS09475
uniprot id: W0L6C9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1441930:Z042 RS15420
gene id: 1441930:Z042_RS15420
uniprot id: W0L793
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS18115
gene id: 1441930:Z042_RS18115
uniprot id: W0LI38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

1441930:Z042 RS23030
gene id: 1441930:Z042_RS23030
uniprot id: A0A0D4ZYM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1441930:Z042 RS15845
gene id: 1441930:Z042_RS15845
uniprot id: W0LF67
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS21770
gene id: 1441930:Z042_RS21770
uniprot id: W0LGD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1441930:Z042 RS23955
gene id: 1441930:Z042_RS23955
uniprot id: W0LBE8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1441930:Z042 RS04025
gene id: 1441930:Z042_RS04025
uniprot id: W0L940
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1441930:Z042 RS07485
gene id: 1441930:Z042_RS07485
uniprot id: W0LBK7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1441930:Z042 RS16520
gene id: 1441930:Z042_RS16520
uniprot id: W0LKA2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS15355
gene id: 1441930:Z042_RS15355
uniprot id: W0L7N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1441930:Z042 RS14370
gene id: 1441930:Z042_RS14370
uniprot id: W0L7T9
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1441930:Z042 RS03035
gene id: 1441930:Z042_RS03035
uniprot id: W0LES8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates influx of magnesium ions.
messages: Membrane

1441930:Z042 RS15225
gene id: 1441930:Z042_RS15225
uniprot id: W0L7C5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1441930:Z042 RS04675
gene id: 1441930:Z042_RS04675
uniprot id: W0LCM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
messages: Cell inner membrane
messages: Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.
messages: Homodimer.
messages: Membrane

1441930:Z042 RS07780
gene id: 1441930:Z042_RS07780
uniprot id: W0L706
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1441930:Z042 RS23830
gene id: 1441930:Z042_RS23830
uniprot id: W0LBG8
names: Similarity
messages: Belongs to the histone deacetylase family.

1441930:Z042 RS13470
gene id: 1441930:Z042_RS13470
uniprot id: W0L4E5
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS16825
gene id: 1441930:Z042_RS16825
uniprot id: W0LEN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1441930:Z042 RS17385
gene id: 1441930:Z042_RS17385
uniprot id: W0LJQ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1441930:Z042 RS23090
gene id: 1441930:Z042_RS23090
uniprot id: W0LBH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlaE exporter family.
messages: Cell inner membrane
messages: Exports L-alanine.

1441930:Z042 RS01950
gene id: 1441930:Z042_RS01950
uniprot id: W0LA73
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1441930:Z042 RS17000
gene id: 1441930:Z042_RS17000
uniprot id: W0LIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1441930:Z042 RS24015
gene id: 1441930:Z042_RS24015
uniprot id: W0LGE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS12715
gene id: 1441930:Z042_RS12715
uniprot id: W0L4J7
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS07605
gene id: 1441930:Z042_RS07605
uniprot id: W0L737
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1441930:Z042 RS19365
gene id: 1441930:Z042_RS19365
uniprot id: W0LDH4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS04520
gene id: 1441930:Z042_RS04520
uniprot id: W0L8N5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1441930:Z042 RS06615
gene id: 1441930:Z042_RS06615
uniprot id: W0LCW6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1441930:Z042 RS15205
gene id: 1441930:Z042_RS15205
uniprot id: W0L3K4
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1441930:Z042 RS09460
gene id: 1441930:Z042_RS09460
uniprot id: W0LA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

1441930:Z042 RS17260
gene id: 1441930:Z042_RS17260
uniprot id: W0LJT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1441930:Z042 RS01405
gene id: 1441930:Z042_RS01405
uniprot id: W0LAF8
names: Similarity
messages: Belongs to the ArsC family.

1441930:Z042 RS07830
gene id: 1441930:Z042_RS07830
uniprot id: W0L6Z8
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1441930:Z042 RS02725
gene id: 1441930:Z042_RS02725
uniprot id: W0L9J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

1441930:Z042 RS20455
gene id: 1441930:Z042_RS20455
uniprot id: W0LD64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1441930:Z042 RS15335
gene id: 1441930:Z042_RS15335
uniprot id: W0L8D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1441930:Z042 RS02010
gene id: 1441930:Z042_RS02010
uniprot id: W0LDZ5
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1441930:Z042 RS18575
gene id: 1441930:Z042_RS18575
uniprot id: W0LHW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1441930:Z042 RS05395
gene id: 1441930:Z042_RS05395
uniprot id: W0L889
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS05995
gene id: 1441930:Z042_RS05995
uniprot id: W0LC11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1441930:Z042 RS07600
gene id: 1441930:Z042_RS07600
uniprot id: W0LCC5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1441930:Z042 RS21100
gene id: 1441930:Z042_RS21100
uniprot id: W0LCV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1441930:Z042 RS21785
gene id: 1441930:Z042_RS21785
uniprot id: W0LCI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1441930:Z042 RS07410
gene id: 1441930:Z042_RS07410
uniprot id: W0L7D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1441930:Z042 RS05465
gene id: 1441930:Z042_RS05465
uniprot id: W0LDI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS15240
gene id: 1441930:Z042_RS15240
uniprot id: W0L3K0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1441930:Z042 RS04205
gene id: 1441930:Z042_RS04205
uniprot id: W0LD73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1441930:Z042 RS10750
gene id: 1441930:Z042_RS10750
uniprot id: W0L5Q6
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

1441930:Z042 RS11505
gene id: 1441930:Z042_RS11505
uniprot id: W0L9H3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1441930:Z042 RS19930
gene id: 1441930:Z042_RS19930
uniprot id: W0LHA5
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

1441930:Z042 RS19605
gene id: 1441930:Z042_RS19605
uniprot id: W0LDM2
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS05885
gene id: 1441930:Z042_RS05885
uniprot id: W0L893
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1441930:Z042 RS11190
gene id: 1441930:Z042_RS11190
uniprot id: W0LAG6
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS13435
gene id: 1441930:Z042_RS13435
uniprot id: W0L8J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class A bacterial acid phosphatase family.
messages: Periplasm

1441930:Z042 RS12500
gene id: 1441930:Z042_RS12500
uniprot id: W0L8Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1441930:Z042 RS13735
gene id: 1441930:Z042_RS13735
uniprot id: W0L974
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1441930:Z042 RS13215
gene id: 1441930:Z042_RS13215
uniprot id: W0L899
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
messages: Cell membrane
messages: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
messages: Membrane

1441930:Z042 RS09685
gene id: 1441930:Z042_RS09685
uniprot id: W0LB89
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1441930:Z042 RS20565
gene id: 1441930:Z042_RS20565
uniprot id: W0LI18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS06800
gene id: 1441930:Z042_RS06800
uniprot id: W0L7H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

1441930:Z042 RS14345
gene id: 1441930:Z042_RS14345
uniprot id: A0A0D4ZXJ4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1441930:Z042 RS07915
gene id: 1441930:Z042_RS07915
uniprot id: W0L751
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1441930:Z042 RS11125
gene id: 1441930:Z042_RS11125
uniprot id: W0L5J3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1441930:Z042 RS07685
gene id: 1441930:Z042_RS07685
uniprot id: W0LBG5
names: Subcellular Location Annotation
messages: Cytoplasm

1441930:Z042 RS10485
gene id: 1441930:Z042_RS10485
uniprot id: W0L9N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS24020
gene id: 1441930:Z042_RS24020
uniprot id: W0LF61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS10720
gene id: 1441930:Z042_RS10720
uniprot id: W0L9V8
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS11740
gene id: 1441930:Z042_RS11740
uniprot id: W0L9E6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1441930:Z042 RS12110
gene id: 1441930:Z042_RS12110
uniprot id: W0L508
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS22925
gene id: 1441930:Z042_RS22925
uniprot id: W0LFR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BtuF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

1441930:Z042 RS17055
gene id: 1441930:Z042_RS17055
uniprot id: W0LEW4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1441930:Z042 RS15300
gene id: 1441930:Z042_RS15300
uniprot id: A0A0D4ZY71
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS16735
gene id: 1441930:Z042_RS16735
uniprot id: W0LF29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

1441930:Z042 RS22570
gene id: 1441930:Z042_RS22570
uniprot id: W0LFY3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1441930:Z042 RS09385
gene id: 1441930:Z042_RS09385
uniprot id: W0L665
names: Similarity
messages: Belongs to the carbamate kinase family.

1441930:Z042 RS23150
gene id: 1441930:Z042_RS23150
uniprot id: W0LBS2
names: Caution
names: Function
messages: Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS12275
gene id: 1441930:Z042_RS12275
uniprot id: W0L4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1441930:Z042 RS05170
gene id: 1441930:Z042_RS05170
uniprot id: W0L8C4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1441930:Z042 RS00010
gene id: 1441930:Z042_RS00010
uniprot id: W0LAV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS02700
gene id: 1441930:Z042_RS02700
uniprot id: W0L9K2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1441930:Z042 RS09690
gene id: 1441930:Z042_RS09690
uniprot id: W0LA31
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

1441930:Z042 RS20935
gene id: 1441930:Z042_RS20935
uniprot id: W0LCY2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1441930:Z042 RS24150
gene id: 1441930:Z042_RS24150
uniprot id: W0LF42
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS19185
gene id: 1441930:Z042_RS19185
uniprot id: W0LDX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I11 (ecotin) family.
messages: General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
messages: Homodimer.
messages: Periplasm

1441930:Z042 RS19330
gene id: 1441930:Z042_RS19330
uniprot id: W0LDI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1441930:Z042 RS01590
gene id: 1441930:Z042_RS01590
uniprot id: W0LEI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

1441930:Z042 RS05295
gene id: 1441930:Z042_RS05295
uniprot id: W0L8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1441930:Z042 RS18770
gene id: 1441930:Z042_RS18770
uniprot id: W0LJ25
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1441930:Z042 RS24310
gene id: 1441930:Z042_RS24310
uniprot id: W0LF15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1441930:Z042 RS11830
gene id: 1441930:Z042_RS11830
uniprot id: W0L9A2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane
messages: Type II secretion system is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. Forms homomultimers.

1441930:Z042 RS16400
gene id: 1441930:Z042_RS16400
uniprot id: W0LEX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1441930:Z042 RS01630
gene id: 1441930:Z042_RS01630
uniprot id: W0LAC7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1441930:Z042 RS18635
gene id: 1441930:Z042_RS18635
uniprot id: W0LI37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1441930:Z042 RS15820
gene id: 1441930:Z042_RS15820
uniprot id: W0LF71
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1441930:Z042 RS06475
gene id: 1441930:Z042_RS06475
uniprot id: W0LC35
names: Similarity
messages: Belongs to the CTP synthase family.

1441930:Z042 RS17995
gene id: 1441930:Z042_RS17995
uniprot id: W0LIF9
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS17465
gene id: 1441930:Z042_RS17465
uniprot id: W0LID0
names: Similarity
messages: Belongs to the YciI family.

1441930:Z042 RS08695
gene id: 1441930:Z042_RS08695
uniprot id: W0L6U2
names: Similarity
messages: Belongs to the UPF0231 family.

1441930:Z042 RS20955
gene id: 1441930:Z042_RS20955
uniprot id: W0LH25
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1441930:Z042 RS11975
gene id: 1441930:Z042_RS11975
uniprot id: W0L528
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1441930:Z042 RS09885
gene id: 1441930:Z042_RS09885
uniprot id: W0L5X2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS10885
gene id: 1441930:Z042_RS10885
uniprot id: W0L9F6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS09290
gene id: 1441930:Z042_RS09290
uniprot id: W0LA98
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1441930:Z042 RS09605
gene id: 1441930:Z042_RS09605
uniprot id: W0L6A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1441930:Z042 RS19355
gene id: 1441930:Z042_RS19355
uniprot id: W0LIT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1441930:Z042 RS09195
gene id: 1441930:Z042_RS09195
uniprot id: W0L6A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS23085
gene id: 1441930:Z042_RS23085
uniprot id: W0LFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

1441930:Z042 RS21580
gene id: 1441930:Z042_RS21580
uniprot id: W0LCM6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1441930:Z042 RS10675
gene id: 1441930:Z042_RS10675
uniprot id: W0L5R7
names: Similarity
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.

1441930:Z042 RS20555
gene id: 1441930:Z042_RS20555
uniprot id: W0LH86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1441930:Z042 RS20570
gene id: 1441930:Z042_RS20570
uniprot id: W0LGZ5
names: Function
names: Similarity
messages: Belongs to the cycloisomerase 2 family.
messages: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1441930:Z042 RS08595
gene id: 1441930:Z042_RS08595
uniprot id: W0LAP2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1441930:Z042 RS15895
gene id: 1441930:Z042_RS15895
uniprot id: W0LF59
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1441930:Z042 RS09230
gene id: 1441930:Z042_RS09230
uniprot id: W0L6G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1441930:Z042 RS22505
gene id: 1441930:Z042_RS22505
uniprot id: W0LBS7
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1441930:Z042 RS16805
gene id: 1441930:Z042_RS16805
uniprot id: W0LJ08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1441930:Z042 RS02805
gene id: 1441930:Z042_RS02805
uniprot id: W0LDY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS13510
gene id: 1441930:Z042_RS13510
uniprot id: W0L996
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.

1441930:Z042 RS06945
gene id: 1441930:Z042_RS06945
uniprot id: W0LBH8
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

1441930:Z042 RS03565
gene id: 1441930:Z042_RS03565
uniprot id: W0LEH3
names: Similarity
messages: Belongs to the barstar family.

1441930:Z042 RS13710
gene id: 1441930:Z042_RS13710
uniprot id: W0L8F7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1441930:Z042 RS11015
gene id: 1441930:Z042_RS11015
uniprot id: W0L9Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS10835
gene id: 1441930:Z042_RS10835
uniprot id: W0L9G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1441930:Z042 RS01085
gene id: 1441930:Z042_RS01085
uniprot id: W0LER2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1441930:Z042 RS24220
gene id: 1441930:Z042_RS24220
uniprot id: W0LBA9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1441930:Z042 RS10185
gene id: 1441930:Z042_RS10185
uniprot id: W0L5S3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1441930:Z042 RS16075
gene id: 1441930:Z042_RS16075
uniprot id: W0LF27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS00135
gene id: 1441930:Z042_RS00135
uniprot id: W0LG71
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1441930:Z042 RS11835
gene id: 1441930:Z042_RS11835
uniprot id: W0L556
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS13065
gene id: 1441930:Z042_RS13065
uniprot id: W0L8C0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS14985
gene id: 1441930:Z042_RS14985
uniprot id: W0L7H0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS20000
gene id: 1441930:Z042_RS20000
uniprot id: W0LDE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

1441930:Z042 RS18465
gene id: 1441930:Z042_RS18465
uniprot id: W0LE92
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1441930:Z042 RS04285
gene id: 1441930:Z042_RS04285
uniprot id: W0L900
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1441930:Z042 RS15120
gene id: 1441930:Z042_RS15120
uniprot id: W0L3L9
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1441930:Z042 RS03780
gene id: 1441930:Z042_RS03780
uniprot id: W0LD45
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1441930:Z042 RS10300
gene id: 1441930:Z042_RS10300
uniprot id: W0L5Y1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1441930:Z042 RS15545
gene id: 1441930:Z042_RS15545
uniprot id: W0L3E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1441930:Z042 RS04935
gene id: 1441930:Z042_RS04935
uniprot id: W0LDR3
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.

1441930:Z042 RS19030
gene id: 1441930:Z042_RS19030
uniprot id: W0LDZ8
names: Subcellular Location Annotation
messages: Cytoplasm

1441930:Z042 RS22345
gene id: 1441930:Z042_RS22345
uniprot id: W0LG14
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

1441930:Z042 RS09560
gene id: 1441930:Z042_RS09560
uniprot id: W0LBB5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS02820
gene id: 1441930:Z042_RS02820
uniprot id: W0LDL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

1441930:Z042 RS16205
gene id: 1441930:Z042_RS16205
uniprot id: W0LKE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS16675
gene id: 1441930:Z042_RS16675
uniprot id: W0LF41
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1441930:Z042 RS00385
gene id: 1441930:Z042_RS00385
uniprot id: W0LAP5
names: Similarity
messages: Belongs to the UPF0306 family.

1441930:Z042 RS12025
gene id: 1441930:Z042_RS12025
uniprot id: W0L4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1441930:Z042 RS06960
gene id: 1441930:Z042_RS06960
uniprot id: W0L7L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

1441930:Z042 RS08760
gene id: 1441930:Z042_RS08760
uniprot id: W0LAL3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1441930:Z042 RS15315
gene id: 1441930:Z042_RS15315
uniprot id: W0L3D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1441930:Z042 RS04605
gene id: 1441930:Z042_RS04605
uniprot id: W0LD07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose mutarotase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the anomeric conversion of L-rhamnose.

1441930:Z042 RS18260
gene id: 1441930:Z042_RS18260
uniprot id: W0LIA9
names: Function
names: Similarity
messages: Belongs to the EfeM/EfeO family.
messages: Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component.

1441930:Z042 RS20720
gene id: 1441930:Z042_RS20720
uniprot id: W0LH61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1441930:Z042 RS04820
gene id: 1441930:Z042_RS04820
uniprot id: W0L8Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1441930:Z042 RS19420
gene id: 1441930:Z042_RS19420
uniprot id: W0LLP5
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS11820
gene id: 1441930:Z042_RS11820
uniprot id: W0L8Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1441930:Z042 RS23020
gene id: 1441930:Z042_RS23020
uniprot id: W0LBU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1441930:Z042 RS20690
gene id: 1441930:Z042_RS20690
uniprot id: W0LGX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1441930:Z042 RS05990
gene id: 1441930:Z042_RS05990
uniprot id: W0LD98
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1441930:Z042 RS08825
gene id: 1441930:Z042_RS08825
uniprot id: W0L6R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS15265
gene id: 1441930:Z042_RS15265
uniprot id: W0L7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS12385
gene id: 1441930:Z042_RS12385
uniprot id: W0L9S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS01040
gene id: 1441930:Z042_RS01040
uniprot id: W0LAL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1441930:Z042 RS22845
gene id: 1441930:Z042_RS22845
uniprot id: W0LFT0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.

1441930:Z042 RS11970
gene id: 1441930:Z042_RS11970
uniprot id: W0L971
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1441930:Z042 RS22870
gene id: 1441930:Z042_RS22870
uniprot id: W0LFS6
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS06400
gene id: 1441930:Z042_RS06400
uniprot id: W0LC51
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1441930:Z042 RS22695
gene id: 1441930:Z042_RS22695
uniprot id: W0LFV7
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1441930:Z042 RS20840
gene id: 1441930:Z042_RS20840
uniprot id: W0LCN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1441930:Z042 RS03935
gene id: 1441930:Z042_RS03935
uniprot id: W0LD19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

1441930:Z042 RS11810
gene id: 1441930:Z042_RS11810
uniprot id: W0L572
names: Similarity
messages: Belongs to the GSP C family.

1441930:Z042 RS21130
gene id: 1441930:Z042_RS21130
uniprot id: W0LHT3
names: Similarity
messages: Belongs to the UPF0250 family.

1441930:Z042 RS22840
gene id: 1441930:Z042_RS22840
uniprot id: W0LH11
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1441930:Z042 RS22305
gene id: 1441930:Z042_RS22305
uniprot id: W0LGC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1441930:Z042 RS01205
gene id: 1441930:Z042_RS01205
uniprot id: W0LA88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1441930:Z042 RS21015
gene id: 1441930:Z042_RS21015
uniprot id: W0LCX2
names: Similarity
messages: Belongs to the YjdM family.

1441930:Z042 RS13055
gene id: 1441930:Z042_RS13055
uniprot id: W0L4K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

1441930:Z042 RS21145
gene id: 1441930:Z042_RS21145
uniprot id: W0LH00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

1441930:Z042 RS07525
gene id: 1441930:Z042_RS07525
uniprot id: W0LB65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1441930:Z042 RS12245
gene id: 1441930:Z042_RS12245
uniprot id: W0L926
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1441930:Z042 RS00870
gene id: 1441930:Z042_RS00870
uniprot id: W0LAF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1441930:Z042 RS11465
gene id: 1441930:Z042_RS11465
uniprot id: W0L977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS22265
gene id: 1441930:Z042_RS22265
uniprot id: W0LHB1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1441930:Z042 RS03735
gene id: 1441930:Z042_RS03735
uniprot id: W0LDF5
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

1441930:Z042 RS23465
gene id: 1441930:Z042_RS23465
uniprot id: W0LBA3
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1441930:Z042 RS12485
gene id: 1441930:Z042_RS12485
uniprot id: W0L9Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1441930:Z042 RS19025
gene id: 1441930:Z042_RS19025
uniprot id: W0LHY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1441930:Z042 RS11965
gene id: 1441930:Z042_RS11965
uniprot id: W0L4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1441930:Z042 RS14770
gene id: 1441930:Z042_RS14770
uniprot id: W0L7P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm

1441930:Z042 RS20480
gene id: 1441930:Z042_RS20480
uniprot id: W0LD59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS18620
gene id: 1441930:Z042_RS18620
uniprot id: W0LJ51
names: Subcellular Location Annotation
messages: Cytoplasm

1441930:Z042 RS16580
gene id: 1441930:Z042_RS16580
uniprot id: W0LJ80
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

1441930:Z042 RS07630
gene id: 1441930:Z042_RS07630
uniprot id: W0L733
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS13110
gene id: 1441930:Z042_RS13110
uniprot id: W0L4J4
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1441930:Z042 RS07505
gene id: 1441930:Z042_RS07505
uniprot id: W0L757
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS02445
gene id: 1441930:Z042_RS02445
uniprot id: W0LA00
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1441930:Z042 RS20810
gene id: 1441930:Z042_RS20810
uniprot id: W0LGU7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1441930:Z042 RS04770
gene id: 1441930:Z042_RS04770
uniprot id: W0LDT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1441930:Z042 RS18280
gene id: 1441930:Z042_RS18280
uniprot id: W0LE04
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

1441930:Z042 RS12205
gene id: 1441930:Z042_RS12205
uniprot id: W0L8R7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS23515
gene id: 1441930:Z042_RS23515
uniprot id: W0LB93
names: Similarity
messages: Belongs to the UPF0246 family.

1441930:Z042 RS18650
gene id: 1441930:Z042_RS18650
uniprot id: W0LHU9
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS10685
gene id: 1441930:Z042_RS10685
uniprot id: W0L9J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS10170
gene id: 1441930:Z042_RS10170
uniprot id: W0L604
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1441930:Z042 RS19090
gene id: 1441930:Z042_RS19090
uniprot id: W0LHN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1441930:Z042 RS12650
gene id: 1441930:Z042_RS12650
uniprot id: W0L9L9
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: To H.influenzae HI_0842.

1441930:Z042 RS05570
gene id: 1441930:Z042_RS05570
uniprot id: W0L8E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

1441930:Z042 RS22310
gene id: 1441930:Z042_RS22310
uniprot id: W0LC65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1441930:Z042 RS17355
gene id: 1441930:Z042_RS17355
uniprot id: W0LER4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1441930:Z042 RS04330
gene id: 1441930:Z042_RS04330
uniprot id: W0L8R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1441930:Z042 RS16815
gene id: 1441930:Z042_RS16815
uniprot id: W0LK20
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1441930:Z042 RS08860
gene id: 1441930:Z042_RS08860
uniprot id: W0LAJ7
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1441930:Z042 RS22550
gene id: 1441930:Z042_RS22550
uniprot id: W0LBS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1441930:Z042 RS03675
gene id: 1441930:Z042_RS03675
uniprot id: W0LD66
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1441930:Z042 RS12530
gene id: 1441930:Z042_RS12530
uniprot id: W0L4T2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1441930:Z042 RS11205
gene id: 1441930:Z042_RS11205
uniprot id: W0L9M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0370 family.
messages: Cell membrane

1441930:Z042 RS20505
gene id: 1441930:Z042_RS20505
uniprot id: W0LH94
names: Similarity
messages: Belongs to the MoaD family.

1441930:Z042 RS08870
gene id: 1441930:Z042_RS08870
uniprot id: W0LAV9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1441930:Z042 RS05750
gene id: 1441930:Z042_RS05750
uniprot id: W0L827
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1441930:Z042 RS16445
gene id: 1441930:Z042_RS16445
uniprot id: W0LJ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

1441930:Z042 RS20940
gene id: 1441930:Z042_RS20940
uniprot id: W0LHW0
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS10830
gene id: 1441930:Z042_RS10830
uniprot id: W0LAM5
names: Similarity
messages: Belongs to the YfgM family.

1441930:Z042 RS05605
gene id: 1441930:Z042_RS05605
uniprot id: W0LDF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1441930:Z042 RS15595
gene id: 1441930:Z042_RS15595
uniprot id: W0L7I8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1441930:Z042 RS21050
gene id: 1441930:Z042_RS21050
uniprot id: W0LGQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS03005
gene id: 1441930:Z042_RS03005
uniprot id: W0LET3
names: Similarity
messages: Belongs to the Rht family.

1441930:Z042 RS23590
gene id: 1441930:Z042_RS23590
uniprot id: W0LFD1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS09900
gene id: 1441930:Z042_RS09900
uniprot id: W0LB49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1441930:Z042 RS04225
gene id: 1441930:Z042_RS04225
uniprot id: W0L8S9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1441930:Z042 RS03385
gene id: 1441930:Z042_RS03385
uniprot id: W0L9J7
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS03425
gene id: 1441930:Z042_RS03425
uniprot id: W0LDC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1441930:Z042 RS00550
gene id: 1441930:Z042_RS00550
uniprot id: W0LAY9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EcpA/MatB fimbrillin family.
messages: Fimbrium
messages: Self-associates. Forms filaments. Interacts with EcpD.

1441930:Z042 RS05285
gene id: 1441930:Z042_RS05285
uniprot id: W0L8A4
names: Similarity
messages: Belongs to the FGGY kinase family.

1441930:Z042 RS06970
gene id: 1441930:Z042_RS06970
uniprot id: W0LBH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoA family.
messages: Interacts with PBP1a.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).

1441930:Z042 RS24070
gene id: 1441930:Z042_RS24070
uniprot id: W0LF51
names: Subunit
messages: Monomer.

1441930:Z042 RS06555
gene id: 1441930:Z042_RS06555
uniprot id: W0LC18
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1441930:Z042 RS05980
gene id: 1441930:Z042_RS05980
uniprot id: W0LCF3
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1441930:Z042 RS15255
gene id: 1441930:Z042_RS15255
uniprot id: W0L7C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1441930:Z042 RS23120
gene id: 1441930:Z042_RS23120
uniprot id: W0LBG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1441930:Z042 RS06340
gene id: 1441930:Z042_RS06340
uniprot id: W0LC74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Binds G3P.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1441930:Z042 RS22955
gene id: 1441930:Z042_RS22955
uniprot id: W0LBK3
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS14490
gene id: 1441930:Z042_RS14490
uniprot id: W0L7S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

1441930:Z042 RS13885
gene id: 1441930:Z042_RS13885
uniprot id: W0L498
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1441930:Z042 RS14835
gene id: 1441930:Z042_RS14835
uniprot id: A0A0D4ZYI8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1441930:Z042 RS11050
gene id: 1441930:Z042_RS11050
uniprot id: W0LAJ0
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS13915
gene id: 1441930:Z042_RS13915
uniprot id: W0L952
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1441930:Z042 RS02780
gene id: 1441930:Z042_RS02780
uniprot id: W0LDY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS01240
gene id: 1441930:Z042_RS01240
uniprot id: W0LAI2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS11725
gene id: 1441930:Z042_RS11725
uniprot id: W0L941
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1441930:Z042 RS00295
gene id: 1441930:Z042_RS00295
uniprot id: W0LB35
names: Similarity
messages: Belongs to the UPF0213 family.

1441930:Z042 RS10020
gene id: 1441930:Z042_RS10020
uniprot id: W0L625
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS03765
gene id: 1441930:Z042_RS03765
uniprot id: W0LDF1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1441930:Z042 RS22190
gene id: 1441930:Z042_RS22190
uniprot id: W0LHD1
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

1441930:Z042 RS22485
gene id: 1441930:Z042_RS22485
uniprot id: W0LG89
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1441930:Z042 RS23065
gene id: 1441930:Z042_RS23065
uniprot id: W0LBI1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS11515
gene id: 1441930:Z042_RS11515
uniprot id: W0LAB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1441930:Z042 RS07640
gene id: 1441930:Z042_RS07640
uniprot id: W0L795
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1441930:Z042 RS01195
gene id: 1441930:Z042_RS01195
uniprot id: W0LFN5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1441930:Z042 RS21960
gene id: 1441930:Z042_RS21960
uniprot id: W0LHH6
names: Similarity
messages: Belongs to the FGGY kinase family.

1441930:Z042 RS18480
gene id: 1441930:Z042_RS18480
uniprot id: W0LDW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1441930:Z042 RS01025
gene id: 1441930:Z042_RS01025
uniprot id: W0LEI1
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1441930:Z042 RS12375
gene id: 1441930:Z042_RS12375
uniprot id: W0L4W2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1441930:Z042 RS03110
gene id: 1441930:Z042_RS03110
uniprot id: W0L9P0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1441930:Z042 RS14360
gene id: 1441930:Z042_RS14360
uniprot id: W0L430
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS11185
gene id: 1441930:Z042_RS11185
uniprot id: W0L5I4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1441930:Z042 RS04875
gene id: 1441930:Z042_RS04875
uniprot id: W0LDR7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1441930:Z042 RS08115
gene id: 1441930:Z042_RS08115
uniprot id: W0LC32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS04860
gene id: 1441930:Z042_RS04860
uniprot id: W0L8G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

1441930:Z042 RS15210
gene id: 1441930:Z042_RS15210
uniprot id: A0A0D4ZYG5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS02850
gene id: 1441930:Z042_RS02850
uniprot id: W0L9H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1441930:Z042 RS04375
gene id: 1441930:Z042_RS04375
uniprot id: W0LE10
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1441930:Z042 RS22475
gene id: 1441930:Z042_RS22475
uniprot id: W0LFZ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1441930:Z042 RS16000
gene id: 1441930:Z042_RS16000
uniprot id: W0LJ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1441930:Z042 RS18275
gene id: 1441930:Z042_RS18275
uniprot id: W0LI10
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1441930:Z042 RS23080
gene id: 1441930:Z042_RS23080
uniprot id: W0LGW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1441930:Z042 RS10625
gene id: 1441930:Z042_RS10625
uniprot id: W0L5S4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1441930:Z042 RS21115
gene id: 1441930:Z042_RS21115
uniprot id: W0LCI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1441930:Z042 RS04810
gene id: 1441930:Z042_RS04810
uniprot id: W0L8H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1441930:Z042 RS12355
gene id: 1441930:Z042_RS12355
uniprot id: W0L9T1
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1441930:Z042 RS05505
gene id: 1441930:Z042_RS05505
uniprot id: W0L869
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1441930:Z042 RS11060
gene id: 1441930:Z042_RS11060
uniprot id: W0L9P4
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS14865
gene id: 1441930:Z042_RS14865
uniprot id: W0L7W8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1441930:Z042 RS20710
gene id: 1441930:Z042_RS20710
uniprot id: W0LHZ5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1441930:Z042 RS00425
gene id: 1441930:Z042_RS00425
uniprot id: W0LET8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1441930:Z042 RS21155
gene id: 1441930:Z042_RS21155
uniprot id: W0LHT0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1441930:Z042 RS11615
gene id: 1441930:Z042_RS11615
uniprot id: W0LAA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1441930:Z042 RS15775
gene id: 1441930:Z042_RS15775
uniprot id: W0LJB8
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1441930:Z042 RS15935
gene id: 1441930:Z042_RS15935
uniprot id: W0LFK1
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

1441930:Z042 RS12615
gene id: 1441930:Z042_RS12615
uniprot id: W0L8J4
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS20855
gene id: 1441930:Z042_RS20855
uniprot id: W0LHX2
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS05290
gene id: 1441930:Z042_RS05290
uniprot id: W0LCP8
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1441930:Z042 RS12820
gene id: 1441930:Z042_RS12820
uniprot id: W0L8S8
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS16780
gene id: 1441930:Z042_RS16780
uniprot id: W0LJ13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1441930:Z042 RS14305
gene id: 1441930:Z042_RS14305
uniprot id: W0L3W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

1441930:Z042 RS07665
gene id: 1441930:Z042_RS07665
uniprot id: W0L792
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1441930:Z042 RS11805
gene id: 1441930:Z042_RS11805
uniprot id: A0A0D4ZYE4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1441930:Z042 RS02390
gene id: 1441930:Z042_RS02390
uniprot id: W0LF31
names: Similarity
messages: Belongs to the FGGY kinase family.

1441930:Z042 RS11980
gene id: 1441930:Z042_RS11980
uniprot id: W0L9Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1441930:Z042 RS02795
gene id: 1441930:Z042_RS02795
uniprot id: W0LDL8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1441930:Z042 RS23000
gene id: 1441930:Z042_RS23000
uniprot id: W0LGY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecM family.
messages: Periplasm
messages: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
messages: cytosol

1441930:Z042 RS14080
gene id: 1441930:Z042_RS14080
uniprot id: W0L924
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1441930:Z042 RS16260
gene id: 1441930:Z042_RS16260
uniprot id: A0A0D4ZXL3
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS14350
gene id: 1441930:Z042_RS14350
uniprot id: W0L3W3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1441930:Z042 RS01680
gene id: 1441930:Z042_RS01680
uniprot id: W0LAB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1441930:Z042 RS18825
gene id: 1441930:Z042_RS18825
uniprot id: W0LHS0
names: Similarity
messages: Belongs to the UPF0434 family.

1441930:Z042 RS22950
gene id: 1441930:Z042_RS22950
uniprot id: W0LFQ8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1441930:Z042 RS21450
gene id: 1441930:Z042_RS21450
uniprot id: W0LGI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1441930:Z042 RS15730
gene id: 1441930:Z042_RS15730
uniprot id: W0LJM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1441930:Z042 RS13765
gene id: 1441930:Z042_RS13765
uniprot id: W0L816
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS13270
gene id: 1441930:Z042_RS13270
uniprot id: W0L891
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1441930:Z042 RS22690
gene id: 1441930:Z042_RS22690
uniprot id: W0LH36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1441930:Z042 RS22010
gene id: 1441930:Z042_RS22010
uniprot id: W0LCF0
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1441930:Z042 RS18435
gene id: 1441930:Z042_RS18435
uniprot id: W0LI78
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1441930:Z042 RS03945
gene id: 1441930:Z042_RS03945
uniprot id: W0LDB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1441930:Z042 RS16810
gene id: 1441930:Z042_RS16810
uniprot id: W0LF14
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1441930:Z042 RS21345
gene id: 1441930:Z042_RS21345
uniprot id: W0LCR5
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS18515
gene id: 1441930:Z042_RS18515
uniprot id: W0LE80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1441930:Z042 RS10190
gene id: 1441930:Z042_RS10190
uniprot id: W0LA51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

1441930:Z042 RS22240
gene id: 1441930:Z042_RS22240
uniprot id: W0LHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1441930:Z042 RS03220
gene id: 1441930:Z042_RS03220
uniprot id: W0LDF6
names: Similarity
messages: Belongs to the thioredoxin family.

1441930:Z042 RS04270
gene id: 1441930:Z042_RS04270
uniprot id: W0LCW0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1441930:Z042 RS07275
gene id: 1441930:Z042_RS07275
uniprot id: W0LBP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1441930:Z042 RS15405
gene id: 1441930:Z042_RS15405
uniprot id: W0L7M1
names: Similarity
messages: Belongs to the peptidase S49 family.

1441930:Z042 RS06450
gene id: 1441930:Z042_RS06450
uniprot id: W0LC40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1441930:Z042 RS18805
gene id: 1441930:Z042_RS18805
uniprot id: W0LDQ6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

1441930:Z042 RS02495
gene id: 1441930:Z042_RS02495
uniprot id: W0L9Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1441930:Z042 RS21590
gene id: 1441930:Z042_RS21590
uniprot id: W0LGG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1441930:Z042 RS13565
gene id: 1441930:Z042_RS13565
uniprot id: W0L838
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1441930:Z042 RS17250
gene id: 1441930:Z042_RS17250
uniprot id: W0LIS7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-90 and Arg-93) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form.

1441930:Z042 RS18795
gene id: 1441930:Z042_RS18795
uniprot id: W0LJ21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

1441930:Z042 RS15330
gene id: 1441930:Z042_RS15330
uniprot id: W0L3I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1441930:Z042 RS18095
gene id: 1441930:Z042_RS18095
uniprot id: W0LE43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

1441930:Z042 RS22470
gene id: 1441930:Z042_RS22470
uniprot id: A0A0D4ZXY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1441930:Z042 RS04145
gene id: 1441930:Z042_RS04145
uniprot id: W0LCY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1441930:Z042 RS16420
gene id: 1441930:Z042_RS16420
uniprot id: W0LJ18
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1441930:Z042 RS00305
gene id: 1441930:Z042_RS00305
uniprot id: W0LEV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS20650
gene id: 1441930:Z042_RS20650
uniprot id: W0LGY0
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS19405
gene id: 1441930:Z042_RS19405
uniprot id: W0LIS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1441930:Z042 RS18405
gene id: 1441930:Z042_RS18405
uniprot id: W0LDX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1441930:Z042 RS18010
gene id: 1441930:Z042_RS18010
uniprot id: W0LI60
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS16365
gene id: 1441930:Z042_RS16365
uniprot id: W0LKC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.
messages: Homohexamer.

1441930:Z042 RS07615
gene id: 1441930:Z042_RS07615
uniprot id: W0L799
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

1441930:Z042 RS23670
gene id: 1441930:Z042_RS23670
uniprot id: W0LB59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1441930:Z042 RS23680
gene id: 1441930:Z042_RS23680
uniprot id: W0LFN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

1441930:Z042 RS09295
gene id: 1441930:Z042_RS09295
uniprot id: W0L682
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands.

1441930:Z042 RS08875
gene id: 1441930:Z042_RS08875
uniprot id: W0L6R0
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS20925
gene id: 1441930:Z042_RS20925
uniprot id: W0LCL7
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1441930:Z042 RS09110
gene id: 1441930:Z042_RS09110
uniprot id: W0L6C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS22935
gene id: 1441930:Z042_RS22935
uniprot id: W0LG16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1441930:Z042 RS08575
gene id: 1441930:Z042_RS08575
uniprot id: W0L6N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1441930:Z042 RS14955
gene id: 1441930:Z042_RS14955
uniprot id: W0L7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Periplasm

1441930:Z042 RS22185
gene id: 1441930:Z042_RS22185
uniprot id: W0LCA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm

1441930:Z042 RS17965
gene id: 1441930:Z042_RS17965
uniprot id: W0LE65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1441930:Z042 RS22975
gene id: 1441930:Z042_RS22975
uniprot id: A0A0D4ZYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1441930:Z042 RS16265
gene id: 1441930:Z042_RS16265
uniprot id: W0LFE1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1441930:Z042 RS10760
gene id: 1441930:Z042_RS10760
uniprot id: W0L9H6
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1441930:Z042 RS02535
gene id: 1441930:Z042_RS02535
uniprot id: W0L9M7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1441930:Z042 RS19175
gene id: 1441930:Z042_RS19175
uniprot id: W0LDK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane

1441930:Z042 RS22275
gene id: 1441930:Z042_RS22275
uniprot id: W0LBW4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1441930:Z042 RS18740
gene id: 1441930:Z042_RS18740
uniprot id: W0LE42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS08130
gene id: 1441930:Z042_RS08130
uniprot id: W0LB81
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1441930:Z042 RS12390
gene id: 1441930:Z042_RS12390
uniprot id: W0L8N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS20430
gene id: 1441930:Z042_RS20430
uniprot id: W0LH22
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1441930:Z042 RS00900
gene id: 1441930:Z042_RS00900
uniprot id: W0LEU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1441930:Z042 RS18475
gene id: 1441930:Z042_RS18475
uniprot id: W0LHX8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1441930:Z042 RS05005
gene id: 1441930:Z042_RS05005
uniprot id: W0LCU5
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

1441930:Z042 RS00905
gene id: 1441930:Z042_RS00905
uniprot id: W0LAP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1441930:Z042 RS15170
gene id: 1441930:Z042_RS15170
uniprot id: W0L3K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

1441930:Z042 RS09895
gene id: 1441930:Z042_RS09895
uniprot id: W0L648
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

1441930:Z042 RS11150
gene id: 1441930:Z042_RS11150
uniprot id: W0L5B2
names: Similarity
messages: Belongs to the ArsC family.

1441930:Z042 RS07000
gene id: 1441930:Z042_RS07000
uniprot id: W0LCP4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS17330
gene id: 1441930:Z042_RS17330
uniprot id: W0LER8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1441930:Z042 RS12365
gene id: 1441930:Z042_RS12365
uniprot id: W0L4Q7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1441930:Z042 RS22025
gene id: 1441930:Z042_RS22025
uniprot id: W0LC36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. SbcC subfamily.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1441930:Z042 RS16665
gene id: 1441930:Z042_RS16665
uniprot id: W0LES3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1441930:Z042 RS16835
gene id: 1441930:Z042_RS16835
uniprot id: W0LF10
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS02680
gene id: 1441930:Z042_RS02680
uniprot id: W0LE02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1441930:Z042 RS04140
gene id: 1441930:Z042_RS04140
uniprot id: W0LE54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1441930:Z042 RS03270
gene id: 1441930:Z042_RS03270
uniprot id: W0LEP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

1441930:Z042 RS07235
gene id: 1441930:Z042_RS07235
uniprot id: W0LBP8
names: Similarity
messages: Belongs to the intimin/invasin family.

1441930:Z042 RS22245
gene id: 1441930:Z042_RS22245
uniprot id: W0LG36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1441930:Z042 RS02955
gene id: 1441930:Z042_RS02955
uniprot id: W0LDJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1441930:Z042 RS22155
gene id: 1441930:Z042_RS22155
uniprot id: W0LGI0
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1441930:Z042 RS01595
gene id: 1441930:Z042_RS01595
uniprot id: W0LAD3
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1441930:Z042 RS15130
gene id: 1441930:Z042_RS15130
uniprot id: W0L7E4
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1441930:Z042 RS16550
gene id: 1441930:Z042_RS16550
uniprot id: W0LIZ5
names: Similarity
messages: Belongs to the peptidase C40 family.

1441930:Z042 RS04485
gene id: 1441930:Z042_RS04485
uniprot id: W0LDZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1441930:Z042 RS24380
gene id: 1441930:Z042_RS24380
uniprot id: W0LB82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1441930:Z042 RS00890
gene id: 1441930:Z042_RS00890
uniprot id: W0LEK3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1441930:Z042 RS07700
gene id: 1441930:Z042_RS07700
uniprot id: W0LB32
names: Similarity
messages: Belongs to the archaeal-type GPI family.

1441930:Z042 RS15675
gene id: 1441930:Z042_RS15675
uniprot id: W0LFP4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1441930:Z042 RS03225
gene id: 1441930:Z042_RS03225
uniprot id: W0L9C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1441930:Z042 RS19705
gene id: 1441930:Z042_RS19705
uniprot id: W0LDJ9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1441930:Z042 RS22440
gene id: 1441930:Z042_RS22440
uniprot id: W0LC42
names: Subcellular Location Annotation
messages: Cytoplasm

1441930:Z042 RS16615
gene id: 1441930:Z042_RS16615
uniprot id: W0LJ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

1441930:Z042 RS21585
gene id: 1441930:Z042_RS21585
uniprot id: W0LHM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1441930:Z042 RS22620
gene id: 1441930:Z042_RS22620
uniprot id: W0LFX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1441930:Z042 RS18610
gene id: 1441930:Z042_RS18610
uniprot id: W0LI43
names: Function
names: Similarity
messages: Belongs to the RcsA family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes.

1441930:Z042 RS12145
gene id: 1441930:Z042_RS12145
uniprot id: W0L9W7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1441930:Z042 RS21320
gene id: 1441930:Z042_RS21320
uniprot id: W0LCS0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1441930:Z042 RS22180
gene id: 1441930:Z042_RS22180
uniprot id: W0LGH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1441930:Z042 RS02880
gene id: 1441930:Z042_RS02880
uniprot id: W0LDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1441930:Z042 RS19095
gene id: 1441930:Z042_RS19095
uniprot id: W0LDL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1441930:Z042 RS20545
gene id: 1441930:Z042_RS20545
uniprot id: W0LH01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS16120
gene id: 1441930:Z042_RS16120
uniprot id: W0LFG6
names: Similarity
messages: Belongs to the peptidase C56 family.

1441930:Z042 RS12455
gene id: 1441930:Z042_RS12455
uniprot id: W0L4U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1441930:Z042 RS12325
gene id: 1441930:Z042_RS12325
uniprot id: W0L9T7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1441930:Z042 RS19540
gene id: 1441930:Z042_RS19540
uniprot id: W0LDN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS19590
gene id: 1441930:Z042_RS19590
uniprot id: W0LDB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1441930:Z042 RS07980
gene id: 1441930:Z042_RS07980
uniprot id: W0L6W9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1441930:Z042 RS19015
gene id: 1441930:Z042_RS19015
uniprot id: W0LHP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1441930:Z042 RS24270
gene id: 1441930:Z042_RS24270
uniprot id: W0LBA1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1441930:Z042 RS06395
gene id: 1441930:Z042_RS06395
uniprot id: W0L7P9
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS06115
gene id: 1441930:Z042_RS06115
uniprot id: W0LD77
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1441930:Z042 RS21630
gene id: 1441930:Z042_RS21630
uniprot id: W0LCL5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1441930:Z042 RS23015
gene id: 1441930:Z042_RS23015
uniprot id: W0LG02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1441930:Z042 RS22895
gene id: 1441930:Z042_RS22895
uniprot id: W0LH02
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1441930:Z042 RS23070
gene id: 1441930:Z042_RS23070
uniprot id: W0LFZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1441930:Z042 RS20820
gene id: 1441930:Z042_RS20820
uniprot id: W0LH45
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1441930:Z042 RS11695
gene id: 1441930:Z042_RS11695
uniprot id: W0L532
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS01180
gene id: 1441930:Z042_RS01180
uniprot id: W0LA90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1441930:Z042 RS16465
gene id: 1441930:Z042_RS16465
uniprot id: W0LKB0
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1441930:Z042 RS25305
gene id: 1441930:Z042_RS25305
uniprot id: W0LGZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

1441930:Z042 RS08820
gene id: 1441930:Z042_RS08820
uniprot id: W0LAW6
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1441930:Z042 RS17210
gene id: 1441930:Z042_RS17210
uniprot id: W0LEH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1441930:Z042 RS12090
gene id: 1441930:Z042_RS12090
uniprot id: W0L9X7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1441930:Z042 RS00195
gene id: 1441930:Z042_RS00195
uniprot id: W0LAS2
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS24295
gene id: 1441930:Z042_RS24295
uniprot id: W0LFD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1441930:Z042 RS16755
gene id: 1441930:Z042_RS16755
uniprot id: W0LJ20
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1441930:Z042 RS09745
gene id: 1441930:Z042_RS09745
uniprot id: W0L677
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1441930:Z042 RS15510
gene id: 1441930:Z042_RS15510
uniprot id: W0L7K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family. RNase II subfamily.
messages: Cytoplasm
messages: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.

1441930:Z042 RS19670
gene id: 1441930:Z042_RS19670
uniprot id: W0LD99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

1441930:Z042 RS21965
gene id: 1441930:Z042_RS21965
uniprot id: W0LGA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS19665
gene id: 1441930:Z042_RS19665
uniprot id: W0LHE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS04545
gene id: 1441930:Z042_RS04545
uniprot id: W0L8N0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1441930:Z042 RS06110
gene id: 1441930:Z042_RS06110
uniprot id: W0L849
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1441930:Z042 RS06585
gene id: 1441930:Z042_RS06585
uniprot id: W0L7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1441930:Z042 RS17410
gene id: 1441930:Z042_RS17410
uniprot id: W0LJP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1441930:Z042 RS23555
gene id: 1441930:Z042_RS23555
uniprot id: W0LGL4
names: Caution
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. GpmB subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS11870
gene id: 1441930:Z042_RS11870
uniprot id: W0L8X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1441930:Z042 RS00925
gene id: 1441930:Z042_RS00925
uniprot id: W0LEJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1441930:Z042 RS16185
gene id: 1441930:Z042_RS16185
uniprot id: W0LJ56
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1441930:Z042 RS17945
gene id: 1441930:Z042_RS17945
uniprot id: W0LEI5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

1441930:Z042 RS03070
gene id: 1441930:Z042_RS03070
uniprot id: W0LDH5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

1441930:Z042 RS15175
gene id: 1441930:Z042_RS15175
uniprot id: W0L8G4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1441930:Z042 RS19040
gene id: 1441930:Z042_RS19040
uniprot id: W0LHP5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1441930:Z042 RS06975
gene id: 1441930:Z042_RS06975
uniprot id: W0LGQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1441930:Z042 RS18125
gene id: 1441930:Z042_RS18125
uniprot id: W0LID2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1441930:Z042 RS14945
gene id: 1441930:Z042_RS14945
uniprot id: W0L3P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS04475
gene id: 1441930:Z042_RS04475
uniprot id: W0LD31
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1441930:Z042 RS07325
gene id: 1441930:Z042_RS07325
uniprot id: W0L785
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1441930:Z042 RS16795
gene id: 1441930:Z042_RS16795
uniprot id: W0LIR5
names: Similarity
messages: Belongs to the UPF0260 family.

1441930:Z042 RS14475
gene id: 1441930:Z042_RS14475
uniprot id: W0L839
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1441930:Z042 RS00865
gene id: 1441930:Z042_RS00865
uniprot id: W0LEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS05705
gene id: 1441930:Z042_RS05705
uniprot id: W0LCJ4
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS20815
gene id: 1441930:Z042_RS20815
uniprot id: W0LCN7
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

1441930:Z042 RS07450
gene id: 1441930:Z042_RS07450
uniprot id: W0L764
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1441930:Z042 RS15915
gene id: 1441930:Z042_RS15915
uniprot id: W0LKJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1441930:Z042 RS07260
gene id: 1441930:Z042_RS07260
uniprot id: W0LCJ3
names: Similarity
messages: Belongs to the MotB family.

1441930:Z042 RS11000
gene id: 1441930:Z042_RS11000
uniprot id: W0LAJ8
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

1441930:Z042 RS12330
gene id: 1441930:Z042_RS12330
uniprot id: W0L8Q0
names: Subunit
messages: Homooctamer.

1441930:Z042 RS09220
gene id: 1441930:Z042_RS09220
uniprot id: W0L699
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1441930:Z042 RS02470
gene id: 1441930:Z042_RS02470
uniprot id: W0L9Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rsd/AlgQ family.
messages: Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
messages: Cytoplasm
messages: Interacts with RpoD.

1441930:Z042 RS04280
gene id: 1441930:Z042_RS04280
uniprot id: W0LD62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS19485
gene id: 1441930:Z042_RS19485
uniprot id: W0LHN5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1441930:Z042 RS15605
gene id: 1441930:Z042_RS15605
uniprot id: W0L877
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap.

1441930:Z042 RS02330
gene id: 1441930:Z042_RS02330
uniprot id: W0LA18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1441930:Z042 RS23640
gene id: 1441930:Z042_RS23640
uniprot id: W0LGJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1441930:Z042 RS06495
gene id: 1441930:Z042_RS06495
uniprot id: W0LBQ5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1441930:Z042 RS11380
gene id: 1441930:Z042_RS11380
uniprot id: W0L5F2
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1441930:Z042 RS01390
gene id: 1441930:Z042_RS01390
uniprot id: W0LEB3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1441930:Z042 RS18455
gene id: 1441930:Z042_RS18455
uniprot id: W0LDW7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1441930:Z042 RS09950
gene id: 1441930:Z042_RS09950
uniprot id: W0LB37
names: Subcellular Location Annotation
messages: Cytoplasm

1441930:Z042 RS08785
gene id: 1441930:Z042_RS08785
uniprot id: W0LAK8
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1441930:Z042 RS12435
gene id: 1441930:Z042_RS12435
uniprot id: W0L9R4
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS12055
gene id: 1441930:Z042_RS12055
uniprot id: W0L957
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS01445
gene id: 1441930:Z042_RS01445
uniprot id: W0LEA1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1441930:Z042 RS00770
gene id: 1441930:Z042_RS00770
uniprot id: W0LFW4
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS09775
gene id: 1441930:Z042_RS09775
uniprot id: W0LB73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

1441930:Z042 RS10870
gene id: 1441930:Z042_RS10870
uniprot id: W0L9S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1441930:Z042 RS23480
gene id: 1441930:Z042_RS23480
uniprot id: W0LGN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1441930:Z042 RS02885
gene id: 1441930:Z042_RS02885
uniprot id: W0L9S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

1441930:Z042 RS12815
gene id: 1441930:Z042_RS12815
uniprot id: W0L4H7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1441930:Z042 RS01215
gene id: 1441930:Z042_RS01215
uniprot id: W0LAI7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1441930:Z042 RS12470
gene id: 1441930:Z042_RS12470
uniprot id: W0L4P0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1441930:Z042 RS04560
gene id: 1441930:Z042_RS04560
uniprot id: W0LDX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1441930:Z042 RS21885
gene id: 1441930:Z042_RS21885
uniprot id: W0LCG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS02910
gene id: 1441930:Z042_RS02910
uniprot id: W0L9S4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

1441930:Z042 RS00235
gene id: 1441930:Z042_RS00235
uniprot id: W0LB44
names: Similarity
messages: Belongs to the phosphopentomutase family.

1441930:Z042 RS15905
gene id: 1441930:Z042_RS15905
uniprot id: W0LJJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1441930:Z042 RS06355
gene id: 1441930:Z042_RS06355
uniprot id: W0LD15
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: By maltose.
messages: Cell outer membrane
messages: Homotrimer formed of three 18-stranded antiparallel beta-barrels, containing three independent channels.
messages: Involved in the transport of maltose and maltodextrins.
messages: Membrane

1441930:Z042 RS12195
gene id: 1441930:Z042_RS12195
uniprot id: W0L4Z5
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1441930:Z042 RS16410
gene id: 1441930:Z042_RS16410
uniprot id: W0LFB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1441930:Z042 RS21350
gene id: 1441930:Z042_RS21350
uniprot id: W0LHQ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS09035
gene id: 1441930:Z042_RS09035
uniprot id: W0LAT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS14775
gene id: 1441930:Z042_RS14775
uniprot id: W0L3Q6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.
messages: Homotrimer.

1441930:Z042 RS21745
gene id: 1441930:Z042_RS21745
uniprot id: W0LGE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1441930:Z042 RS19610
gene id: 1441930:Z042_RS19610
uniprot id: W0LIL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1441930:Z042 RS17440
gene id: 1441930:Z042_RS17440
uniprot id: W0LID6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1441930:Z042 RS20950
gene id: 1441930:Z042_RS20950
uniprot id: W0LCL0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1441930:Z042 RS09015
gene id: 1441930:Z042_RS09015
uniprot id: W0L6N7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS07890
gene id: 1441930:Z042_RS07890
uniprot id: W0L754
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1441930:Z042 RS17195
gene id: 1441930:Z042_RS17195
uniprot id: W0LET9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1441930:Z042 RS01655
gene id: 1441930:Z042_RS01655
uniprot id: W0LAC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1441930:Z042 RS06570
gene id: 1441930:Z042_RS06570
uniprot id: W0LBP2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1441930:Z042 RS04500
gene id: 1441930:Z042_RS04500
uniprot id: W0LD26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1441930:Z042 RS08565
gene id: 1441930:Z042_RS08565
uniprot id: W0LBX4
names: Similarity
messages: Belongs to the UPF0235 family.

1441930:Z042 RS03725
gene id: 1441930:Z042_RS03725
uniprot id: W0LD56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

1441930:Z042 RS21010
gene id: 1441930:Z042_RS21010
uniprot id: W0LH20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1441930:Z042 RS14880
gene id: 1441930:Z042_RS14880
uniprot id: W0L7J2
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

1441930:Z042 RS10780
gene id: 1441930:Z042_RS10780
uniprot id: W0LAN4
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1441930:Z042 RS24050
gene id: 1441930:Z042_RS24050
uniprot id: W0LB02
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

1441930:Z042 RS19755
gene id: 1441930:Z042_RS19755
uniprot id: W0LDJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

1441930:Z042 RS03730
gene id: 1441930:Z042_RS03730
uniprot id: W0L919
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1441930:Z042 RS05960
gene id: 1441930:Z042_RS05960
uniprot id: W0L878
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1441930:Z042 RS08665
gene id: 1441930:Z042_RS08665
uniprot id: W0L6U7
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1441930:Z042 RS21105
gene id: 1441930:Z042_RS21105
uniprot id: W0LHT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1441930:Z042 RS06170
gene id: 1441930:Z042_RS06170
uniprot id: W0LBY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1441930:Z042 RS20070
gene id: 1441930:Z042_RS20070
uniprot id: W0LDC9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1441930:Z042 RS05945
gene id: 1441930:Z042_RS05945
uniprot id: W0LC21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.

1441930:Z042 RS06155
gene id: 1441930:Z042_RS06155
uniprot id: W0LCB8
names: Similarity
messages: Belongs to the DprA/Smf family.

1441930:Z042 RS19390
gene id: 1441930:Z042_RS19390
uniprot id: W0LDG9
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

1441930:Z042 RS15160
gene id: 1441930:Z042_RS15160
uniprot id: W0L3F9
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1441930:Z042 RS04765
gene id: 1441930:Z042_RS04765
uniprot id: W0L8R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1441930:Z042 RS12020
gene id: 1441930:Z042_RS12020
uniprot id: W0L8V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

1441930:Z042 RS14430
gene id: 1441930:Z042_RS14430
uniprot id: W0L7T2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1441930:Z042 RS16565
gene id: 1441930:Z042_RS16565
uniprot id: W0LK91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS16560
gene id: 1441930:Z042_RS16560
uniprot id: W0LF88
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

1441930:Z042 RS23130
gene id: 1441930:Z042_RS23130
uniprot id: W0LBS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1441930:Z042 RS21865
gene id: 1441930:Z042_RS21865
uniprot id: W0LHI8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1441930:Z042 RS09985
gene id: 1441930:Z042_RS09985
uniprot id: W0L5V3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1441930:Z042 RS19140
gene id: 1441930:Z042_RS19140
uniprot id: W0LIW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1441930:Z042 RS12410
gene id: 1441930:Z042_RS12410
uniprot id: W0L9S0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1441930:Z042 RS23045
gene id: 1441930:Z042_RS23045
uniprot id: W0LFZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1441930:Z042 RS18615
gene id: 1441930:Z042_RS18615
uniprot id: W0LE64
names: Similarity
messages: Belongs to the DsrB family.

1441930:Z042 RS15140
gene id: 1441930:Z042_RS15140
uniprot id: W0L7R5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1441930:Z042 RS14010
gene id: 1441930:Z042_RS14010
uniprot id: W0L476
names: Similarity
messages: Belongs to the DapA family.

1441930:Z042 RS16405
gene id: 1441930:Z042_RS16405
uniprot id: W0LJB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1441930:Z042 RS17270
gene id: 1441930:Z042_RS17270
uniprot id: W0LEG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1441930:Z042 RS02675
gene id: 1441930:Z042_RS02675
uniprot id: W0L9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1441930:Z042 RS21740
gene id: 1441930:Z042_RS21740
uniprot id: W0LHK4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1441930:Z042 RS04735
gene id: 1441930:Z042_RS04735
uniprot id: W0LCY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

1441930:Z042 RS01160
gene id: 1441930:Z042_RS01160
uniprot id: W0LEQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1441930:Z042 RS05455
gene id: 1441930:Z042_RS05455
uniprot id: W0LCM5
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1441930:Z042 RS05515
gene id: 1441930:Z042_RS05515
uniprot id: W0L8F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell membrane
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

1441930:Z042 RS07705
gene id: 1441930:Z042_RS07705
uniprot id: W0L720
names: Similarity
messages: Belongs to the archaeal-type GPI family.

1441930:Z042 RS15350
gene id: 1441930:Z042_RS15350
uniprot id: W0L3C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1441930:Z042 RS08610
gene id: 1441930:Z042_RS08610
uniprot id: W0L6V4
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

1441930:Z042 RS23470
gene id: 1441930:Z042_RS23470
uniprot id: W0LFR8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1441930:Z042 RS00795
gene id: 1441930:Z042_RS00795
uniprot id: W0LAR4
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

1441930:Z042 RS06940
gene id: 1441930:Z042_RS06940
uniprot id: W0LCQ5
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

1441930:Z042 RS16225
gene id: 1441930:Z042_RS16225
uniprot id: W0LJD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tus family.
messages: Cytoplasm
messages: Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence.

1441930:Z042 RS19560
gene id: 1441930:Z042_RS19560
uniprot id: W0LHF8
names: Similarity
messages: Belongs to the UPF0053 family.

1441930:Z042 RS06025
gene id: 1441930:Z042_RS06025
uniprot id: W0L7Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1441930:Z042 RS20590
gene id: 1441930:Z042_RS20590
uniprot id: W0LI13
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1441930:Z042 RS06840
gene id: 1441930:Z042_RS06840
uniprot id: W0LCS6
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

1441930:Z042 RS07835
gene id: 1441930:Z042_RS07835
uniprot id: W0LBD5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1441930:Z042 RS15530
gene id: 1441930:Z042_RS15530
uniprot id: W0L774
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS06080
gene id: 1441930:Z042_RS06080
uniprot id: W0LCD2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1441930:Z042 RS16620
gene id: 1441930:Z042_RS16620
uniprot id: W0LF79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SufE family.
messages: Cytoplasm
messages: Homodimer. Interacts with SufS.
messages: Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.

1441930:Z042 RS16570
gene id: 1441930:Z042_RS16570
uniprot id: W0LIZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS23185
gene id: 1441930:Z042_RS23185
uniprot id: W0LFL0
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1441930:Z042 RS05100
gene id: 1441930:Z042_RS05100
uniprot id: W0L8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1441930:Z042 RS04815
gene id: 1441930:Z042_RS04815
uniprot id: W0LCW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M20A family. ArgE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS15450
gene id: 1441930:Z042_RS15450
uniprot id: W0L786
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1441930:Z042 RS05590
gene id: 1441930:Z042_RS05590
uniprot id: W0L855
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1441930:Z042 RS00995
gene id: 1441930:Z042_RS00995
uniprot id: W0LFS3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1441930:Z042 RS06175
gene id: 1441930:Z042_RS06175
uniprot id: W0L7V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1441930:Z042 RS17935
gene id: 1441930:Z042_RS17935
uniprot id: W0LE70
names: Function
names: Similarity
messages: Belongs to the N(4)-acetylcytidine amidohydrolase family.
messages: Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).

1441930:Z042 RS05500
gene id: 1441930:Z042_RS05500
uniprot id: W0LC93
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1441930:Z042 RS19375
gene id: 1441930:Z042_RS19375
uniprot id: W0LDT6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

1441930:Z042 RS20625
gene id: 1441930:Z042_RS20625
uniprot id: W0LGY5
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

1441930:Z042 RS20355
gene id: 1441930:Z042_RS20355
uniprot id: W0LH35
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS20880
gene id: 1441930:Z042_RS20880
uniprot id: W0LHW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

1441930:Z042 RS12010
gene id: 1441930:Z042_RS12010
uniprot id: W0L524
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS23930
gene id: 1441930:Z042_RS23930
uniprot id: W0LF73
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1441930:Z042 RS09650
gene id: 1441930:Z042_RS09650
uniprot id: W0LAE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1441930:Z042 RS11345
gene id: 1441930:Z042_RS11345
uniprot id: W0L581
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1441930:Z042 RS19900
gene id: 1441930:Z042_RS19900
uniprot id: W0LIF0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1441930:Z042 RS20875
gene id: 1441930:Z042_RS20875
uniprot id: W0LCZ2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1441930:Z042 RS19005
gene id: 1441930:Z042_RS19005
uniprot id: W0LE03
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS18315
gene id: 1441930:Z042_RS18315
uniprot id: W0LEC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS04660
gene id: 1441930:Z042_RS04660
uniprot id: W0L8T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1441930:Z042 RS07865
gene id: 1441930:Z042_RS07865
uniprot id: W0L758
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS18100
gene id: 1441930:Z042_RS18100
uniprot id: W0LID7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1441930:Z042 RS18220
gene id: 1441930:Z042_RS18220
uniprot id: W0LJB7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS10660
gene id: 1441930:Z042_RS10660
uniprot id: W0L9J5
names: Similarity
messages: Belongs to the P(II) protein family.

1441930:Z042 RS05440
gene id: 1441930:Z042_RS05440
uniprot id: W0LDI9
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

1441930:Z042 RS11315
gene id: 1441930:Z042_RS11315
uniprot id: W0L998
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1441930:Z042 RS05975
gene id: 1441930:Z042_RS05975
uniprot id: W0L7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1441930:Z042 RS21685
gene id: 1441930:Z042_RS21685
uniprot id: W0LCK4
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS10200
gene id: 1441930:Z042_RS10200
uniprot id: W0LAY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS05965
gene id: 1441930:Z042_RS05965
uniprot id: W0LDA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1441930:Z042 RS17245
gene id: 1441930:Z042_RS17245
uniprot id: W0LEG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1441930:Z042 RS08725
gene id: 1441930:Z042_RS08725
uniprot id: W0LBU6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1441930:Z042 RS09145
gene id: 1441930:Z042_RS09145
uniprot id: W0L6I4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1441930:Z042 RS22080
gene id: 1441930:Z042_RS22080
uniprot id: W0LGJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1441930:Z042 RS10755
gene id: 1441930:Z042_RS10755
uniprot id: W0LAN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1441930:Z042 RS23530
gene id: 1441930:Z042_RS23530
uniprot id: W0LGM2
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1441930:Z042 RS10790
gene id: 1441930:Z042_RS10790
uniprot id: W0L5G9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Probably plays an important role in intracellular peptide degradation.

1441930:Z042 RS09045
gene id: 1441930:Z042_RS09045
uniprot id: W0LBN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1441930:Z042 RS09510
gene id: 1441930:Z042_RS09510
uniprot id: W0LBC4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1441930:Z042 RS22985
gene id: 1441930:Z042_RS22985
uniprot id: W0LBJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1441930:Z042 RS10000
gene id: 1441930:Z042_RS10000
uniprot id: W0LB28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS01145
gene id: 1441930:Z042_RS01145
uniprot id: W0LFP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1441930:Z042 RS06485
gene id: 1441930:Z042_RS06485
uniprot id: W0LCY9
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

1441930:Z042 RS00735
gene id: 1441930:Z042_RS00735
uniprot id: W0LEX5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1441930:Z042 RS11220
gene id: 1441930:Z042_RS11220
uniprot id: W0L9B2
names: Similarity
messages: Belongs to the ArsC family.

1441930:Z042 RS17340
gene id: 1441930:Z042_RS17340
uniprot id: W0LIF8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1441930:Z042 RS00885
gene id: 1441930:Z042_RS00885
uniprot id: W0LFU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1441930:Z042 RS06490
gene id: 1441930:Z042_RS06490
uniprot id: A0A0D4ZYB7
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1441930:Z042 RS12580
gene id: 1441930:Z042_RS12580
uniprot id: W0L4S2
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1441930:Z042 RS22990
gene id: 1441930:Z042_RS22990
uniprot id: W0LG07
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1441930:Z042 RS22860
gene id: 1441930:Z042_RS22860
uniprot id: W0LBW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1441930:Z042 RS00400
gene id: 1441930:Z042_RS00400
uniprot id: W0LKC2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1441930:Z042 RS16230
gene id: 1441930:Z042_RS16230
uniprot id: W0LFE6
names: Function
names: Subunit
messages: Homodimer.
messages: Required for resistance to the phenazine antibiotic.

1441930:Z042 RS16555
gene id: 1441930:Z042_RS16555
uniprot id: W0LEV5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1441930:Z042 RS09305
gene id: 1441930:Z042_RS09305
uniprot id: W0L6F6
names: Similarity
messages: Belongs to the RecJ family.

1441930:Z042 RS21855
gene id: 1441930:Z042_RS21855
uniprot id: W0LGM9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1441930:Z042 RS06835
gene id: 1441930:Z042_RS06835
uniprot id: W0L7N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1441930:Z042 RS19625
gene id: 1441930:Z042_RS19625
uniprot id: W0LHL5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

1441930:Z042 RS04690
gene id: 1441930:Z042_RS04690
uniprot id: W0L8T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1441930:Z042 RS13525
gene id: 1441930:Z042_RS13525
uniprot id: W0L8H9
names: Subcellular Location Annotation
messages: Cell inner membrane

1441930:Z042 RS11195
gene id: 1441930:Z042_RS11195
uniprot id: W0L9B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

1441930:Z042 RS21790
gene id: 1441930:Z042_RS21790
uniprot id: W0LHJ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1441930:Z042 RS21670
gene id: 1441930:Z042_RS21670
uniprot id: W0LGF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS18270
gene id: 1441930:Z042_RS18270
uniprot id: W0LJB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1441930:Z042 RS03080
gene id: 1441930:Z042_RS03080
uniprot id: W0LDT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS16875
gene id: 1441930:Z042_RS16875
uniprot id: W0LEM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS21575
gene id: 1441930:Z042_RS21575
uniprot id: W0LGT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1441930:Z042 RS14385
gene id: 1441930:Z042_RS14385
uniprot id: W0L425
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1441930:Z042 RS09080
gene id: 1441930:Z042_RS09080
uniprot id: W0LAE7
names: Similarity
messages: Belongs to the FGGY kinase family.

1441930:Z042 RS20745
gene id: 1441930:Z042_RS20745
uniprot id: W0LH58
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1441930:Z042 RS21035
gene id: 1441930:Z042_RS21035
uniprot id: W0LH18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1441930:Z042 RS19195
gene id: 1441930:Z042_RS19195
uniprot id: W0LHM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1441930:Z042 RS11055
gene id: 1441930:Z042_RS11055
uniprot id: W0L9D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1441930:Z042 RS03350
gene id: 1441930:Z042_RS03350
uniprot id: W0LEN2
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS21570
gene id: 1441930:Z042_RS21570
uniprot id: W0LC99
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1441930:Z042 RS18415
gene id: 1441930:Z042_RS18415
uniprot id: W0LEA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1441930:Z042 RS12540
gene id: 1441930:Z042_RS12540
uniprot id: W0L8L0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1441930:Z042 RS02475
gene id: 1441930:Z042_RS02475
uniprot id: W0LF17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1441930:Z042 RS20440
gene id: 1441930:Z042_RS20440
uniprot id: W0LCV7
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

1441930:Z042 RS15565
gene id: 1441930:Z042_RS15565
uniprot id: W0L383
names: Similarity
messages: Belongs to the PspA/IM30 family.

1441930:Z042 RS05110
gene id: 1441930:Z042_RS05110
uniprot id: W0LCS4
names: Similarity
messages: Belongs to the UPF0261 family.

1441930:Z042 RS18420
gene id: 1441930:Z042_RS18420
uniprot id: W0LJ84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1441930:Z042 RS07300
gene id: 1441930:Z042_RS07300
uniprot id: W0LBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1441930:Z042 RS09640
gene id: 1441930:Z042_RS09640
uniprot id: W0LBA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

1441930:Z042 RS01125
gene id: 1441930:Z042_RS01125
uniprot id: W0LEG0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1441930:Z042 RS09795
gene id: 1441930:Z042_RS09795
uniprot id: W0L667
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1441930:Z042 RS18015
gene id: 1441930:Z042_RS18015
uniprot id: W0LE56
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS20655
gene id: 1441930:Z042_RS20655
uniprot id: W0LCR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1441930:Z042 RS16695
gene id: 1441930:Z042_RS16695
uniprot id: W0LJ31
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
messages: Cytoplasm
messages: In the transfer reaction, the free carboxyl group of lipoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Monomer.

1441930:Z042 RS14965
gene id: 1441930:Z042_RS14965
uniprot id: W0L7U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.
messages: Cell inner membrane

1441930:Z042 RS13505
gene id: 1441930:Z042_RS13505
uniprot id: W0L4D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane

1441930:Z042 RS07730
gene id: 1441930:Z042_RS07730
uniprot id: W0L716
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1441930:Z042 RS15655
gene id: 1441930:Z042_RS15655
uniprot id: W0LKN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.
messages: Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.

1441930:Z042 RS18850
gene id: 1441930:Z042_RS18850
uniprot id: W0LHR6
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1441930:Z042 RS19130
gene id: 1441930:Z042_RS19130
uniprot id: W0LHW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS12115
gene id: 1441930:Z042_RS12115
uniprot id: W0L9X1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1441930:Z042 RS11260
gene id: 1441930:Z042_RS11260
uniprot id: W0L591
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS15360
gene id: 1441930:Z042_RS15360
uniprot id: W0L3H7
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

1441930:Z042 RS06930
gene id: 1441930:Z042_RS06930
uniprot id: W0LBV3
names: Similarity
messages: Belongs to the glutamate synthase family.

1441930:Z042 RS06030
gene id: 1441930:Z042_RS06030
uniprot id: W0LCE5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1441930:Z042 RS21475
gene id: 1441930:Z042_RS21475
uniprot id: W0LGI2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1441930:Z042 RS02875
gene id: 1441930:Z042_RS02875
uniprot id: W0L9H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1441930:Z042 RS09155
gene id: 1441930:Z042_RS09155
uniprot id: W0LAC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1441930:Z042 RS12490
gene id: 1441930:Z042_RS12490
uniprot id: W0L8L8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1441930:Z042 RS14970
gene id: 1441930:Z042_RS14970
uniprot id: W0L3P1
names: Similarity
messages: Belongs to the pyruvate kinase family.

1441930:Z042 RS20235
gene id: 1441930:Z042_RS20235
uniprot id: W0LHD0
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS23335
gene id: 1441930:Z042_RS23335
uniprot id: W0LFU5
names: Similarity
messages: Belongs to the VgrG protein family.

1441930:Z042 RS04040
gene id: 1441930:Z042_RS04040
uniprot id: W0L8W6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1441930:Z042 RS16540
gene id: 1441930:Z042_RS16540
uniprot id: W0LF91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1441930:Z042 RS12415
gene id: 1441930:Z042_RS12415
uniprot id: W0L8N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1441930:Z042 RS15180
gene id: 1441930:Z042_RS15180
uniprot id: W0L7D2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1441930:Z042 RS02855
gene id: 1441930:Z042_RS02855
uniprot id: W0LDX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1441930:Z042 RS07875
gene id: 1441930:Z042_RS07875
uniprot id: W0LAZ2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1441930:Z042 RS16720
gene id: 1441930:Z042_RS16720
uniprot id: W0LJ26
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

1441930:Z042 RS18760
gene id: 1441930:Z042_RS18760
uniprot id: W0LI16
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1441930:Z042 RS21905
gene id: 1441930:Z042_RS21905
uniprot id: W0LGL8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1441930:Z042 RS23735
gene id: 1441930:Z042_RS23735
uniprot id: W0LFA7
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS00485
gene id: 1441930:Z042_RS00485
uniprot id: W0LF39
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1441930:Z042 RS01065
gene id: 1441930:Z042_RS01065
uniprot id: W0LAL4
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS18025
gene id: 1441930:Z042_RS18025
uniprot id: W0LEH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1441930:Z042 RS05445
gene id: 1441930:Z042_RS05445
uniprot id: W0LCA0
names: Similarity
messages: Belongs to the pirin family.

1441930:Z042 RS04885
gene id: 1441930:Z042_RS04885
uniprot id: W0LCI3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1441930:Z042 RS05930
gene id: 1441930:Z042_RS05930
uniprot id: W0LCG3
names: Similarity
messages: Belongs to the SlyX family.

1441930:Z042 RS06370
gene id: 1441930:Z042_RS06370
uniprot id: W0L7Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Monomer.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1441930:Z042 RS07660
gene id: 1441930:Z042_RS07660
uniprot id: W0LBH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1441930:Z042 RS14995
gene id: 1441930:Z042_RS14995
uniprot id: W0L7T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Membrane

1441930:Z042 RS17460
gene id: 1441930:Z042_RS17460
uniprot id: W0LJN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

1441930:Z042 RS22580
gene id: 1441930:Z042_RS22580
uniprot id: W0LG76
names: Subcellular Location Annotation
messages: Membrane

1441930:Z042 RS13770
gene id: 1441930:Z042_RS13770
uniprot id: W0L444
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1441930:Z042 RS21300
gene id: 1441930:Z042_RS21300
uniprot id: W0LHR1
names: Similarity
messages: Belongs to the DapA family.

1441930:Z042 RS18200
gene id: 1441930:Z042_RS18200
uniprot id: W0LE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1441930:Z042 RS05190
gene id: 1441930:Z042_RS05190
uniprot id: W0LCD4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1441930:Z042 RS11275
gene id: 1441930:Z042_RS11275
uniprot id: W0L5H1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1441930:Z042 RS20520
gene id: 1441930:Z042_RS20520
uniprot id: W0LH06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1441930:Z042 RS11090
gene id: 1441930:Z042_RS11090
uniprot id: W0L9N9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane