1437453:BN2145 RS15635
gene id: 1437453:BN2145_RS15635
uniprot id: A0A0F7VPT3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1437453:BN2145 RS19725
gene id: 1437453:BN2145_RS19725
uniprot id: A0A0F7VRJ7
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1437453:BN2145 RS19585
gene id: 1437453:BN2145_RS19585
uniprot id: A0A0F7W249
names: Similarity
messages: Belongs to the FemABX family.

1437453:BN2145 RS30235
gene id: 1437453:BN2145_RS30235
uniprot id: A0A0F7W795
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1437453:BN2145 RS30305
gene id: 1437453:BN2145_RS30305
uniprot id: A0A0F7W7A6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1437453:BN2145 RS02570
gene id: 1437453:BN2145_RS02570
uniprot id: A0A0F7VLL2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1437453:BN2145 RS10655
gene id: 1437453:BN2145_RS10655
uniprot id: A0A0F7VMY4
names: Similarity
messages: Belongs to the IucA/IucC family.

1437453:BN2145 RS07980
gene id: 1437453:BN2145_RS07980
uniprot id: A0A0F7VV31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS13290
gene id: 1437453:BN2145_RS13290
uniprot id: A0A0F7VPW4
names: Similarity
messages: Belongs to the peptidase C40 family.

1437453:BN2145 RS27190
gene id: 1437453:BN2145_RS27190
uniprot id: A0A0F7VVP0
names: Similarity
messages: Belongs to the TrpC family.

1437453:BN2145 RS22325
gene id: 1437453:BN2145_RS22325
uniprot id: A0A0F7W3F6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1437453:BN2145 RS32985
gene id: 1437453:BN2145_RS32985
uniprot id: A0A0F7W8W7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS20555
gene id: 1437453:BN2145_RS20555
uniprot id: A0A0F7W088
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1437453:BN2145 RS22600
gene id: 1437453:BN2145_RS22600
uniprot id: A0A0F7VVF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1437453:BN2145 RS30120
gene id: 1437453:BN2145_RS30120
uniprot id: A0A0F7W307
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1437453:BN2145 RS23035
gene id: 1437453:BN2145_RS23035
uniprot id: A0A0F7W413
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1437453:BN2145 RS23320
gene id: 1437453:BN2145_RS23320
uniprot id: A0A0F7W4A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1437453:BN2145 RS35040
gene id: 1437453:BN2145_RS35040
uniprot id: A0A0F7W9U9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1437453:BN2145 RS29815
gene id: 1437453:BN2145_RS29815
uniprot id: A0A0F7W6Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1437453:BN2145 RS06920
gene id: 1437453:BN2145_RS06920
uniprot id: A0A0F7VPS4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1437453:BN2145 RS19470
gene id: 1437453:BN2145_RS19470
uniprot id: A0A0F7VXB2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1437453:BN2145 RS16530
gene id: 1437453:BN2145_RS16530
uniprot id: A0A0F7VRT0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS21515
gene id: 1437453:BN2145_RS21515
uniprot id: A0A0F7VSG6
names: Similarity
messages: Belongs to the UPF0309 family.

1437453:BN2145 RS22265
gene id: 1437453:BN2145_RS22265
uniprot id: A0A0F7VSW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1437453:BN2145 RS20820
gene id: 1437453:BN2145_RS20820
uniprot id: A0A0F7VS73
names: Similarity
messages: Belongs to the fructosamine kinase family.

1437453:BN2145 RS25780
gene id: 1437453:BN2145_RS25780
uniprot id: A0A0F7W5A5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS09755
gene id: 1437453:BN2145_RS09755
uniprot id: A0A0F7VRE2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS23010
gene id: 1437453:BN2145_RS23010
uniprot id: A0A0F7W408
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1437453:BN2145 RS31530
gene id: 1437453:BN2145_RS31530
uniprot id: A0A0F7W6F9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1437453:BN2145 RS03915
gene id: 1437453:BN2145_RS03915
uniprot id: A0A0F7VR60
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS22665
gene id: 1437453:BN2145_RS22665
uniprot id: A0A0F7VYJ9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1437453:BN2145 RS04780
gene id: 1437453:BN2145_RS04780
uniprot id: A0A0F7VM17
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1437453:BN2145 RS06755
gene id: 1437453:BN2145_RS06755
uniprot id: A0A0F7VMI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1437453:BN2145 RS26995
gene id: 1437453:BN2145_RS26995
uniprot id: A0A0F7W145
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1437453:BN2145 RS30450
gene id: 1437453:BN2145_RS30450
uniprot id: A0A0F7W7D1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS24660
gene id: 1437453:BN2145_RS24660
uniprot id: A0A0F7W2J4
names: Similarity
messages: Belongs to the peptidase M1 family.

1437453:BN2145 RS19430
gene id: 1437453:BN2145_RS19430
uniprot id: A0A0F7W219
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1437453:BN2145 RS11980
gene id: 1437453:BN2145_RS11980
uniprot id: A0A0F7VNC7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS11825
gene id: 1437453:BN2145_RS11825
uniprot id: A0A0F7VSN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1437453:BN2145 RS10315
gene id: 1437453:BN2145_RS10315
uniprot id: A0A0F7VUU4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1437453:BN2145 RS07840
gene id: 1437453:BN2145_RS07840
uniprot id: A0A0F7VQA8
names: Similarity
messages: Belongs to the terpene synthase family.

1437453:BN2145 RS17350
gene id: 1437453:BN2145_RS17350
uniprot id: A0A0F7VQE7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1437453:BN2145 RS25185
gene id: 1437453:BN2145_RS25185
uniprot id: A0A0F7W519
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1437453:BN2145 RS03950
gene id: 1437453:BN2145_RS03950
uniprot id: A0A0F7VL28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted
messages: Strong inhibitor of bacterial serine proteases such as subtilisin.

1437453:BN2145 RS08650
gene id: 1437453:BN2145_RS08650
uniprot id: A0A0F7VTS2
names: Similarity
messages: Belongs to the catalase family.

1437453:BN2145 RS09965
gene id: 1437453:BN2145_RS09965
uniprot id: A0A0F7VNI5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1437453:BN2145 RS32015
gene id: 1437453:BN2145_RS32015
uniprot id: A0A0F7VYC1
names: Similarity
messages: Belongs to the Dps family.

1437453:BN2145 RS16435
gene id: 1437453:BN2145_RS16435
uniprot id: A0A0F7VVG7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1437453:BN2145 RS09230
gene id: 1437453:BN2145_RS09230
uniprot id: A0A0F7VMF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS29850
gene id: 1437453:BN2145_RS29850
uniprot id: A0A0F7W2W0
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1437453:BN2145 RS29945
gene id: 1437453:BN2145_RS29945
uniprot id: A0A0F7W5D7
names: Similarity
messages: Belongs to the barstar family.

1437453:BN2145 RS19740
gene id: 1437453:BN2145_RS19740
uniprot id: A0A0F7VZY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1437453:BN2145 RS06110
gene id: 1437453:BN2145_RS06110
uniprot id: A0A0F7VMB9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1437453:BN2145 RS21960
gene id: 1437453:BN2145_RS21960
uniprot id: A0A0F7VV06
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1437453:BN2145 RS04975
gene id: 1437453:BN2145_RS04975
uniprot id: A0A0F7VL91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1437453:BN2145 RS22060
gene id: 1437453:BN2145_RS22060
uniprot id: A0A0F7VYD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1437453:BN2145 RS02995
gene id: 1437453:BN2145_RS02995
uniprot id: A0A0F7VKW1
names: Similarity
messages: Belongs to the thioesterase family.

1437453:BN2145 RS26660
gene id: 1437453:BN2145_RS26660
uniprot id: A0A0F7W3K1
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1437453:BN2145 RS19540
gene id: 1437453:BN2145_RS19540
uniprot id: A0A0F7VZU3
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS11555
gene id: 1437453:BN2145_RS11555
uniprot id: A0A0F7VP14
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1437453:BN2145 RS15025
gene id: 1437453:BN2145_RS15025
uniprot id: A0A0F7VUP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1437453:BN2145 RS11750
gene id: 1437453:BN2145_RS11750
uniprot id: A0A0F7VSM0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1437453:BN2145 RS29875
gene id: 1437453:BN2145_RS29875
uniprot id: A0A0F7W2W5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS32430
gene id: 1437453:BN2145_RS32430
uniprot id: A0A0F7W8H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS21825
gene id: 1437453:BN2145_RS21825
uniprot id: A0A0F7W369
names: Subcellular Location Annotation
messages: Cytoplasm

1437453:BN2145 RS18375
gene id: 1437453:BN2145_RS18375
uniprot id: A0A0F7VT18
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS06845
gene id: 1437453:BN2145_RS06845
uniprot id: A0A0F7VPR3
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1437453:BN2145 RS34435
gene id: 1437453:BN2145_RS34435
uniprot id: A0A0F7VZL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1437453:BN2145 RS06830
gene id: 1437453:BN2145_RS06830
uniprot id: A0A0F7VMJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1437453:BN2145 RS17170
gene id: 1437453:BN2145_RS17170
uniprot id: A0A0F7VS45
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1437453:BN2145 RS29300
gene id: 1437453:BN2145_RS29300
uniprot id: A0A0F7W6T1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1437453:BN2145 RS12630
gene id: 1437453:BN2145_RS12630
uniprot id: A0A0F7VNJ0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS04795
gene id: 1437453:BN2145_RS04795
uniprot id: A0A0F7VP21
names: Subcellular Location Annotation
messages: Secreted

1437453:BN2145 RS34030
gene id: 1437453:BN2145_RS34030
uniprot id: A0A0F7W7T4
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1437453:BN2145 RS04570
gene id: 1437453:BN2145_RS04570
uniprot id: A0A0F7VRI3
names: Similarity
messages: Belongs to the DapA family.

1437453:BN2145 RS08770
gene id: 1437453:BN2145_RS08770
uniprot id: A0A0F7VVH0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1437453:BN2145 RS08120
gene id: 1437453:BN2145_RS08120
uniprot id: A0A0F7VQL5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1437453:BN2145 RS17675
gene id: 1437453:BN2145_RS17675
uniprot id: A0A0F7VYU4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1437453:BN2145 RS06735
gene id: 1437453:BN2145_RS06735
uniprot id: A0A0F7VMH8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1437453:BN2145 RS12585
gene id: 1437453:BN2145_RS12585
uniprot id: A0A0F7VPE7
names: Similarity
messages: Belongs to the UPF0045 family.

1437453:BN2145 RS29680
gene id: 1437453:BN2145_RS29680
uniprot id: A0A0F7W6W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1437453:BN2145 RS26955
gene id: 1437453:BN2145_RS26955
uniprot id: A0A0F7W5R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1437453:BN2145 RS29635
gene id: 1437453:BN2145_RS29635
uniprot id: A0A0F7W586
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS26520
gene id: 1437453:BN2145_RS26520
uniprot id: A0A0F7VV51
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1437453:BN2145 RS27135
gene id: 1437453:BN2145_RS27135
uniprot id: A0A0F7W3S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1437453:BN2145 RS16260
gene id: 1437453:BN2145_RS16260
uniprot id: A0A0F7VQ15
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS30255
gene id: 1437453:BN2145_RS30255
uniprot id: A0A0F7VZC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1437453:BN2145 RS23445
gene id: 1437453:BN2145_RS23445
uniprot id: A0A0F7VVV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1437453:BN2145 RS30040
gene id: 1437453:BN2145_RS30040
uniprot id: A0A0F7W742
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS26000
gene id: 1437453:BN2145_RS26000
uniprot id: A0A0F7W3B4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS23830
gene id: 1437453:BN2145_RS23830
uniprot id: A0A0F7W4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS11560
gene id: 1437453:BN2145_RS11560
uniprot id: A0A0F7VX60
names: Similarity
messages: Belongs to the UPF0102 family.

1437453:BN2145 RS22090
gene id: 1437453:BN2145_RS22090
uniprot id: A0A0F7VYD4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS17045
gene id: 1437453:BN2145_RS17045
uniprot id: A0A0F7VQC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS04265
gene id: 1437453:BN2145_RS04265
uniprot id: A0A0F7VRB2
names: Similarity
messages: Belongs to the peptidase S33 family.

1437453:BN2145 RS29035
gene id: 1437453:BN2145_RS29035
uniprot id: A0A0F7VWK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1437453:BN2145 RS16215
gene id: 1437453:BN2145_RS16215
uniprot id: A0A0F7VRK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1437453:BN2145 RS21030
gene id: 1437453:BN2145_RS21030
uniprot id: A0A0F7VUM9
names: Similarity
messages: Belongs to the peptidase M1 family.

1437453:BN2145 RS14540
gene id: 1437453:BN2145_RS14540
uniprot id: A0A0F7VZH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1437453:BN2145 RS12085
gene id: 1437453:BN2145_RS12085
uniprot id: A0A0F7VXH6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS24865
gene id: 1437453:BN2145_RS24865
uniprot id: A0A0F7W2N0
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1437453:BN2145 RS22055
gene id: 1437453:BN2145_RS22055
uniprot id: A0A0F7W173
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1437453:BN2145 RS16745
gene id: 1437453:BN2145_RS16745
uniprot id: A0A0F7VVP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS13335
gene id: 1437453:BN2145_RS13335
uniprot id: A0A0F7VNW1
names: Similarity
messages: Belongs to the thioredoxin family.

1437453:BN2145 RS28435
gene id: 1437453:BN2145_RS28435
uniprot id: A0A0F7W6H3
names: Similarity
messages: Belongs to the TlyA family.

1437453:BN2145 RS17020
gene id: 1437453:BN2145_RS17020
uniprot id: A0A0F7VQC0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS07830
gene id: 1437453:BN2145_RS07830
uniprot id: A0A0F7VUW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1437453:BN2145 RS02610
gene id: 1437453:BN2145_RS02610
uniprot id: A0A0F7VN81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1437453:BN2145 RS01825
gene id: 1437453:BN2145_RS01825
uniprot id: A0A0F7VKR4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

1437453:BN2145 RS22525
gene id: 1437453:BN2145_RS22525
uniprot id: A0A0F7VT35
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1437453:BN2145 RS17775
gene id: 1437453:BN2145_RS17775
uniprot id: A0A0F7VSC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1437453:BN2145 RS19365
gene id: 1437453:BN2145_RS19365
uniprot id: A0A0F7VTP2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS10430
gene id: 1437453:BN2145_RS10430
uniprot id: A0A0F7VNQ2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS29230
gene id: 1437453:BN2145_RS29230
uniprot id: A0A0F7W500
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1437453:BN2145 RS14055
gene id: 1437453:BN2145_RS14055
uniprot id: A0A0F7VZ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS03130
gene id: 1437453:BN2145_RS03130
uniprot id: A0A0F7VLQ5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1437453:BN2145 RS03055
gene id: 1437453:BN2145_RS03055
uniprot id: A0A0F7VKW3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1437453:BN2145 RS10785
gene id: 1437453:BN2145_RS10785
uniprot id: A0A0F7VNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS08535
gene id: 1437453:BN2145_RS08535
uniprot id: A0A0F7VM62
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS26250
gene id: 1437453:BN2145_RS26250
uniprot id: A0A0F7W5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS05530
gene id: 1437453:BN2145_RS05530
uniprot id: A0A0F7VM77
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1437453:BN2145 RS26430
gene id: 1437453:BN2145_RS26430
uniprot id: A0A0F7W5L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1437453:BN2145 RS31995
gene id: 1437453:BN2145_RS31995
uniprot id: A0A0F7W0H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS08100
gene id: 1437453:BN2145_RS08100
uniprot id: A0A0F7VM29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

1437453:BN2145 RS29855
gene id: 1437453:BN2145_RS29855
uniprot id: A0A0F7VX07
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1437453:BN2145 RS28265
gene id: 1437453:BN2145_RS28265
uniprot id: A0A0F7VW82
names: Similarity
messages: Belongs to the peptidase U62 family.

1437453:BN2145 RS23580
gene id: 1437453:BN2145_RS23580
uniprot id: A0A0F7VVX1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1437453:BN2145 RS16565
gene id: 1437453:BN2145_RS16565
uniprot id: A0A0F7VYA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1437453:BN2145 RS03190
gene id: 1437453:BN2145_RS03190
uniprot id: A0A0F7VQV5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1437453:BN2145 RS25340
gene id: 1437453:BN2145_RS25340
uniprot id: A0A0F7W543
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1437453:BN2145 RS23110
gene id: 1437453:BN2145_RS23110
uniprot id: A0A0F7W427
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1437453:BN2145 RS27170
gene id: 1437453:BN2145_RS27170
uniprot id: A0A0F7VXM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1437453:BN2145 RS29700
gene id: 1437453:BN2145_RS29700
uniprot id: A0A0F7VZ33
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1437453:BN2145 RS07090
gene id: 1437453:BN2145_RS07090
uniprot id: A0A0F7VPW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1437453:BN2145 RS16310
gene id: 1437453:BN2145_RS16310
uniprot id: A0A0F7VRP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1437453:BN2145 RS24755
gene id: 1437453:BN2145_RS24755
uniprot id: A0A0F7VU81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1437453:BN2145 RS16050
gene id: 1437453:BN2145_RS16050
uniprot id: A0A0F7VXY7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS27580
gene id: 1437453:BN2145_RS27580
uniprot id: A0A0F7W617
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS34985
gene id: 1437453:BN2145_RS34985
uniprot id: A0A0F7W268
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1437453:BN2145 RS10085
gene id: 1437453:BN2145_RS10085
uniprot id: A0A0F7VMN2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1437453:BN2145 RS30975
gene id: 1437453:BN2145_RS30975
uniprot id: A0A0F7W7R5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1437453:BN2145 RS15675
gene id: 1437453:BN2145_RS15675
uniprot id: A0A0F7VXT0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1437453:BN2145 RS30730
gene id: 1437453:BN2145_RS30730
uniprot id: A0A0F7W5X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1437453:BN2145 RS09980
gene id: 1437453:BN2145_RS09980
uniprot id: A0A0F7VRH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1437453:BN2145 RS24520
gene id: 1437453:BN2145_RS24520
uniprot id: A0A0F7VU44
names: Similarity
messages: Belongs to the peptidase M1 family.

1437453:BN2145 RS06300
gene id: 1437453:BN2145_RS06300
uniprot id: A0A0F7VU23
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

1437453:BN2145 RS32815
gene id: 1437453:BN2145_RS32815
uniprot id: A0A0F7W6Y1
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1437453:BN2145 RS18770
gene id: 1437453:BN2145_RS18770
uniprot id: A0A0F7VX21
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS11370
gene id: 1437453:BN2145_RS11370
uniprot id: A0A0F7VSG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS00710
gene id: 1437453:BN2145_RS00710
uniprot id: A0A0F7VKL7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS27145
gene id: 1437453:BN2145_RS27145
uniprot id: A0A0F7VXL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

1437453:BN2145 RS09775
gene id: 1437453:BN2145_RS09775
uniprot id: A0A0F7VW28
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS07370
gene id: 1437453:BN2145_RS07370
uniprot id: A0A0F7VMR8
names: Similarity
messages: Belongs to the CFA/CMAS family.

1437453:BN2145 RS26635
gene id: 1437453:BN2145_RS26635
uniprot id: A0A0F7W3J9
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1437453:BN2145 RS12090
gene id: 1437453:BN2145_RS12090
uniprot id: A0A0F7VVQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1437453:BN2145 RS16360
gene id: 1437453:BN2145_RS16360
uniprot id: A0A0F7VQ25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1437453:BN2145 RS04750
gene id: 1437453:BN2145_RS04750
uniprot id: A0A0F7VL74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

1437453:BN2145 RS24855
gene id: 1437453:BN2145_RS24855
uniprot id: A0A0F7VWE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1437453:BN2145 RS29210
gene id: 1437453:BN2145_RS29210
uniprot id: A0A0F7W2L3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS30105
gene id: 1437453:BN2145_RS30105
uniprot id: A0A0F7VZA2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS28705
gene id: 1437453:BN2145_RS28705
uniprot id: A0A0F7VYQ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS04210
gene id: 1437453:BN2145_RS04210
uniprot id: A0A0F7VLY9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS31430
gene id: 1437453:BN2145_RS31430
uniprot id: A0A0F7W3U6
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS25150
gene id: 1437453:BN2145_RS25150
uniprot id: A0A0F7VWK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS03340
gene id: 1437453:BN2145_RS03340
uniprot id: A0A0F7VLS1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1437453:BN2145 RS10800
gene id: 1437453:BN2145_RS10800
uniprot id: A0A0F7VS48
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1437453:BN2145 RS12650
gene id: 1437453:BN2145_RS12650
uniprot id: A0A0F7VT32
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1437453:BN2145 RS04895
gene id: 1437453:BN2145_RS04895
uniprot id: A0A0F7VRN9
names: Similarity
messages: Belongs to the universal stress protein A family.

1437453:BN2145 RS15715
gene id: 1437453:BN2145_RS15715
uniprot id: A0A0F7VPT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1437453:BN2145 RS11605
gene id: 1437453:BN2145_RS11605
uniprot id: A0A0F7VP18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1437453:BN2145 RS21280
gene id: 1437453:BN2145_RS21280
uniprot id: A0A0F7VY32
names: Subcellular Location Annotation
messages: Cytoplasm

1437453:BN2145 RS05310
gene id: 1437453:BN2145_RS05310
uniprot id: A0A0F7VM57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1437453:BN2145 RS22205
gene id: 1437453:BN2145_RS22205
uniprot id: A0A0F7W1C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1437453:BN2145 RS11290
gene id: 1437453:BN2145_RS11290
uniprot id: A0A0F7VV92
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

1437453:BN2145 RS16750
gene id: 1437453:BN2145_RS16750
uniprot id: A0A0F7VQ83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1437453:BN2145 RS07295
gene id: 1437453:BN2145_RS07295
uniprot id: A0A0F7VPZ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1437453:BN2145 RS15915
gene id: 1437453:BN2145_RS15915
uniprot id: A0A0F7VPW0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1437453:BN2145 RS12145
gene id: 1437453:BN2145_RS12145
uniprot id: A0A0F7VXI6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1437453:BN2145 RS11515
gene id: 1437453:BN2145_RS11515
uniprot id: A0A0F7VVD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1437453:BN2145 RS31165
gene id: 1437453:BN2145_RS31165
uniprot id: A0A0F7W051
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1437453:BN2145 RS16415
gene id: 1437453:BN2145_RS16415
uniprot id: A0A0F7VQ30
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS32325
gene id: 1437453:BN2145_RS32325
uniprot id: A0A0F7W8F2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS30765
gene id: 1437453:BN2145_RS30765
uniprot id: A0A0F7VXN3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1437453:BN2145 RS24870
gene id: 1437453:BN2145_RS24870
uniprot id: A0A0F7VZT4
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1437453:BN2145 RS25365
gene id: 1437453:BN2145_RS25365
uniprot id: A0A0F7VWN7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1437453:BN2145 RS19995
gene id: 1437453:BN2145_RS19995
uniprot id: A0A0F7W2A7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS11505
gene id: 1437453:BN2145_RS11505
uniprot id: A0A0F7VP09
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1437453:BN2145 RS04505
gene id: 1437453:BN2145_RS04505
uniprot id: A0A0F7VL62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS03520
gene id: 1437453:BN2145_RS03520
uniprot id: A0A0F7VSP1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1437453:BN2145 RS18075
gene id: 1437453:BN2145_RS18075
uniprot id: A0A0F7VZ25
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1437453:BN2145 RS32330
gene id: 1437453:BN2145_RS32330
uniprot id: A0A0F7W6R9
names: Similarity
messages: Belongs to the proline racemase family.

1437453:BN2145 RS30480
gene id: 1437453:BN2145_RS30480
uniprot id: A0A0F7W5U4
names: Similarity
messages: Belongs to the thioesterase family.

1437453:BN2145 RS34135
gene id: 1437453:BN2145_RS34135
uniprot id: A0A0F7W5F4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS35150
gene id: 1437453:BN2145_RS35150
uniprot id: A0A0F7VZZ0
names: Subcellular Location Annotation
messages: Cytoplasm

1437453:BN2145 RS23955
gene id: 1437453:BN2145_RS23955
uniprot id: A0A0F7VW35
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1437453:BN2145 RS26810
gene id: 1437453:BN2145_RS26810
uniprot id: A0A0F7W3L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1437453:BN2145 RS24925
gene id: 1437453:BN2145_RS24925
uniprot id: A0A0F7W509
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1437453:BN2145 RS28990
gene id: 1437453:BN2145_RS28990
uniprot id: A0A0F7VYS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1437453:BN2145 RS04970
gene id: 1437453:BN2145_RS04970
uniprot id: A0A0F7VP39
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1437453:BN2145 RS16130
gene id: 1437453:BN2145_RS16130
uniprot id: A0A0F7VPY4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1437453:BN2145 RS02185
gene id: 1437453:BN2145_RS02185
uniprot id: A0A0F7VQC9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1437453:BN2145 RS33745
gene id: 1437453:BN2145_RS33745
uniprot id: A0A0F7W7P2
names: Similarity
messages: Belongs to the CDPS family.

1437453:BN2145 RS05360
gene id: 1437453:BN2145_RS05360
uniprot id: A0A0F7VTJ9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS00070
gene id: 1437453:BN2145_RS00070
uniprot id: A0A0F7VQR3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS13630
gene id: 1437453:BN2145_RS13630
uniprot id: A0A0F7VYM5
names: Similarity
messages: Belongs to the peptidase C40 family.

1437453:BN2145 RS02745
gene id: 1437453:BN2145_RS02745
uniprot id: A0A0F7VKV1
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS33340
gene id: 1437453:BN2145_RS33340
uniprot id: A0A0F7W4V5
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1437453:BN2145 RS24090
gene id: 1437453:BN2145_RS24090
uniprot id: A0A0F7VZC7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1437453:BN2145 RS17325
gene id: 1437453:BN2145_RS17325
uniprot id: A0A0F7VQE5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS17595
gene id: 1437453:BN2145_RS17595
uniprot id: A0A0F7VYT4
names: Similarity
messages: Belongs to the peptidase S13 family.

1437453:BN2145 RS05935
gene id: 1437453:BN2145_RS05935
uniprot id: A0A0F7VLG2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1437453:BN2145 RS14695
gene id: 1437453:BN2145_RS14695
uniprot id: A0A0F7VUH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1437453:BN2145 RS19825
gene id: 1437453:BN2145_RS19825
uniprot id: A0A0F7VRL8
names: Similarity
messages: Belongs to the SCO1/2 family.

1437453:BN2145 RS26755
gene id: 1437453:BN2145_RS26755
uniprot id: A0A0F7W5P0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1437453:BN2145 RS10840
gene id: 1437453:BN2145_RS10840
uniprot id: A0A0F7VWT6
names: Similarity
messages: Belongs to the FPG family.

1437453:BN2145 RS24600
gene id: 1437453:BN2145_RS24600
uniprot id: A0A0F7VWA7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS10425
gene id: 1437453:BN2145_RS10425
uniprot id: A0A0F7VMS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS29125
gene id: 1437453:BN2145_RS29125
uniprot id: A0A0F7W6R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1437453:BN2145 RS32665
gene id: 1437453:BN2145_RS32665
uniprot id: A0A0F7W6W5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS29755
gene id: 1437453:BN2145_RS29755
uniprot id: A0A0F7VZ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1437453:BN2145 RS01790
gene id: 1437453:BN2145_RS01790
uniprot id: A0A0F7VQ66
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1437453:BN2145 RS25605
gene id: 1437453:BN2145_RS25605
uniprot id: A0A0F7W305
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1437453:BN2145 RS10460
gene id: 1437453:BN2145_RS10460
uniprot id: A0A0F7VWN0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS22490
gene id: 1437453:BN2145_RS22490
uniprot id: A0A0F7VYI7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1437453:BN2145 RS27155
gene id: 1437453:BN2145_RS27155
uniprot id: A0A0F7W3T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1437453:BN2145 RS22020
gene id: 1437453:BN2145_RS22020
uniprot id: A0A0F7VV15
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

1437453:BN2145 RS02400
gene id: 1437453:BN2145_RS02400
uniprot id: A0A0F7VN64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1437453:BN2145 RS23870
gene id: 1437453:BN2145_RS23870
uniprot id: A0A0F7VZ72
names: Similarity
messages: Belongs to the universal stress protein A family.

1437453:BN2145 RS34305
gene id: 1437453:BN2145_RS34305
uniprot id: A0A0F7W7X6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1437453:BN2145 RS26965
gene id: 1437453:BN2145_RS26965
uniprot id: A0A0F7W142
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1437453:BN2145 RS22480
gene id: 1437453:BN2145_RS22480
uniprot id: A0A0F7W3J6
names: Similarity
messages: Belongs to the CFA/CMAS family.

1437453:BN2145 RS22375
gene id: 1437453:BN2145_RS22375
uniprot id: A0A0F7W3H9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS33405
gene id: 1437453:BN2145_RS33405
uniprot id: A0A0F7W1C5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS28595
gene id: 1437453:BN2145_RS28595
uniprot id: A0A0F7W4R9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS12840
gene id: 1437453:BN2145_RS12840
uniprot id: A0A0F7VXZ4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS09940
gene id: 1437453:BN2145_RS09940
uniprot id: A0A0F7VNI3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS27520
gene id: 1437453:BN2145_RS27520
uniprot id: A0A0F7VVV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1437453:BN2145 RS22430
gene id: 1437453:BN2145_RS22430
uniprot id: A0A0F7W3I8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437453:BN2145 RS22780
gene id: 1437453:BN2145_RS22780
uniprot id: A0A0F7VVH7
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1437453:BN2145 RS30905
gene id: 1437453:BN2145_RS30905
uniprot id: A0A0F7W5Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS14450
gene id: 1437453:BN2145_RS14450
uniprot id: A0A0F7VUC1
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1437453:BN2145 RS18990
gene id: 1437453:BN2145_RS18990
uniprot id: A0A0F7VZK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS38415
gene id: 1437453:BN2145_RS38415
uniprot id: A0A0F7W365
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS22940
gene id: 1437453:BN2145_RS22940
uniprot id: A0A0F7W1L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

1437453:BN2145 RS33275
gene id: 1437453:BN2145_RS33275
uniprot id: A0A0F7W1A6
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1437453:BN2145 RS05280
gene id: 1437453:BN2145_RS05280
uniprot id: A0A0F7VP78
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS09920
gene id: 1437453:BN2145_RS09920
uniprot id: A0A0F7VW49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS28080
gene id: 1437453:BN2145_RS28080
uniprot id: A0A0F7W491
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS15570
gene id: 1437453:BN2145_RS15570
uniprot id: A0A0F7VR71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1437453:BN2145 RS17225
gene id: 1437453:BN2145_RS17225
uniprot id: A0A0F7VVY1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS27015
gene id: 1437453:BN2145_RS27015
uniprot id: A0A0F7W3R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1437453:BN2145 RS24840
gene id: 1437453:BN2145_RS24840
uniprot id: A0A0F7W2M5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1437453:BN2145 RS10975
gene id: 1437453:BN2145_RS10975
uniprot id: A0A0F7VWU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1437453:BN2145 RS03305
gene id: 1437453:BN2145_RS03305
uniprot id: A0A0F7VKX9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS21645
gene id: 1437453:BN2145_RS21645
uniprot id: A0A0F7VUU6
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1437453:BN2145 RS16535
gene id: 1437453:BN2145_RS16535
uniprot id: A0A0F7W0G5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS25695
gene id: 1437453:BN2145_RS25695
uniprot id: A0A0F7VUM5
names: Similarity
messages: Belongs to the peptidase C15 family.

1437453:BN2145 RS17580
gene id: 1437453:BN2145_RS17580
uniprot id: A0A0F7VQH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1437453:BN2145 RS20240
gene id: 1437453:BN2145_RS20240
uniprot id: A0A0F7VRT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1437453:BN2145 RS31200
gene id: 1437453:BN2145_RS31200
uniprot id: A0A0F7W6C5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1437453:BN2145 RS23910
gene id: 1437453:BN2145_RS23910
uniprot id: A0A0F7W4I6
names: Similarity
messages: Belongs to the group II decarboxylase family.

1437453:BN2145 RS19620
gene id: 1437453:BN2145_RS19620
uniprot id: A0A0F7VXE1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1437453:BN2145 RS05550
gene id: 1437453:BN2145_RS05550
uniprot id: A0A0F7VLD6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS22175
gene id: 1437453:BN2145_RS22175
uniprot id: A0A0F7W3D9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS16105
gene id: 1437453:BN2145_RS16105
uniprot id: A0A0F7VVC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1437453:BN2145 RS18685
gene id: 1437453:BN2145_RS18685
uniprot id: A0A0F7VX15
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1437453:BN2145 RS23835
gene id: 1437453:BN2145_RS23835
uniprot id: A0A0F7W264
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS24790
gene id: 1437453:BN2145_RS24790
uniprot id: A0A0F7W4Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1437453:BN2145 RS32775
gene id: 1437453:BN2145_RS32775
uniprot id: A0A0F7VYU2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1437453:BN2145 RS15115
gene id: 1437453:BN2145_RS15115
uniprot id: A0A0F7VPK5
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1437453:BN2145 RS33065
gene id: 1437453:BN2145_RS33065
uniprot id: A0A0F7W4R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1437453:BN2145 RS10685
gene id: 1437453:BN2145_RS10685
uniprot id: A0A0F7VNS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS16165
gene id: 1437453:BN2145_RS16165
uniprot id: A0A0F7W0B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1437453:BN2145 RS06850
gene id: 1437453:BN2145_RS06850
uniprot id: A0A0F7VLQ0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1437453:BN2145 RS15070
gene id: 1437453:BN2145_RS15070
uniprot id: A0A0F7VX95
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1437453:BN2145 RS12290
gene id: 1437453:BN2145_RS12290
uniprot id: A0A0F7VXP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1437453:BN2145 RS32595
gene id: 1437453:BN2145_RS32595
uniprot id: A0A0F7W4F6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1437453:BN2145 RS32945
gene id: 1437453:BN2145_RS32945
uniprot id: A0A0F7W4N4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1437453:BN2145 RS11385
gene id: 1437453:BN2145_RS11385
uniprot id: A0A0F7VX12
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1437453:BN2145 RS26510
gene id: 1437453:BN2145_RS26510
uniprot id: A0A0F7W3I0
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1437453:BN2145 RS27655
gene id: 1437453:BN2145_RS27655
uniprot id: A0A0F7W623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1437453:BN2145 RS22300
gene id: 1437453:BN2145_RS22300
uniprot id: A0A0F7W3F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1437453:BN2145 RS20755
gene id: 1437453:BN2145_RS20755
uniprot id: A0A0F7W2T5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

1437453:BN2145 RS25425
gene id: 1437453:BN2145_RS25425
uniprot id: A0A0F7VWP6
names: Similarity
messages: Belongs to the YoeB family.

1437453:BN2145 RS26330
gene id: 1437453:BN2145_RS26330
uniprot id: A0A0F7W5J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS05790
gene id: 1437453:BN2145_RS05790
uniprot id: A0A0F7VPE6
names: Similarity
messages: Belongs to the Dps family.

1437453:BN2145 RS27915
gene id: 1437453:BN2145_RS27915
uniprot id: A0A0F7W1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS20515
gene id: 1437453:BN2145_RS20515
uniprot id: A0A0F7VRY1
names: Similarity
messages: Belongs to the CsoR family.

1437453:BN2145 RS18345
gene id: 1437453:BN2145_RS18345
uniprot id: A0A0F7VQT8
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS12405
gene id: 1437453:BN2145_RS12405
uniprot id: A0A0F7VNF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1437453:BN2145 RS23450
gene id: 1437453:BN2145_RS23450
uniprot id: A0A0F7W4C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS22005
gene id: 1437453:BN2145_RS22005
uniprot id: A0A0F7W390
names: Similarity
messages: Belongs to the peptidase S58 family.

1437453:BN2145 RS15300
gene id: 1437453:BN2145_RS15300
uniprot id: A0A0F7VXE2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS16065
gene id: 1437453:BN2145_RS16065
uniprot id: A0A0F7VRH7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1437453:BN2145 RS20895
gene id: 1437453:BN2145_RS20895
uniprot id: A0A0F7VUL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1437453:BN2145 RS23990
gene id: 1437453:BN2145_RS23990
uniprot id: A0A0F7W289
names: Similarity
messages: Belongs to the TPP enzyme family.

1437453:BN2145 RS28220
gene id: 1437453:BN2145_RS28220
uniprot id: A0A0F7VY96
names: Similarity
messages: Belongs to the peptidase S8 family.

1437453:BN2145 RS35590
gene id: 1437453:BN2145_RS35590
uniprot id: A0A0F7VW85
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1437453:BN2145 RS07470
gene id: 1437453:BN2145_RS07470
uniprot id: A0A0F7VUP6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1437453:BN2145 RS07660
gene id: 1437453:BN2145_RS07660
uniprot id: A0A0F7VT96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

1437453:BN2145 RS33145
gene id: 1437453:BN2145_RS33145
uniprot id: A0A0F7VYY8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1437453:BN2145 RS27365
gene id: 1437453:BN2145_RS27365
uniprot id: A0A0F7W3W2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1437453:BN2145 RS10080
gene id: 1437453:BN2145_RS10080
uniprot id: A0A0F7VRJ3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1437453:BN2145 RS34770
gene id: 1437453:BN2145_RS34770
uniprot id: A0A0F7W9T2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1437453:BN2145 RS14375
gene id: 1437453:BN2145_RS14375
uniprot id: A0A0F7VUB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1437453:BN2145 RS28545
gene id: 1437453:BN2145_RS28545
uniprot id: A0A0F7W226
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1437453:BN2145 RS22045
gene id: 1437453:BN2145_RS22045
uniprot id: A0A0F7VV18
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1437453:BN2145 RS08385
gene id: 1437453:BN2145_RS08385
uniprot id: A0A0F7VM50
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS34530
gene id: 1437453:BN2145_RS34530
uniprot id: A0A0F7W5Q2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1437453:BN2145 RS16805
gene id: 1437453:BN2145_RS16805
uniprot id: A0A0F7VRX8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1437453:BN2145 RS06925
gene id: 1437453:BN2145_RS06925
uniprot id: A0A0F7VLQ6
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

1437453:BN2145 RS19605
gene id: 1437453:BN2145_RS19605
uniprot id: A0A0F7VTR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1437453:BN2145 RS19615
gene id: 1437453:BN2145_RS19615
uniprot id: A0A0F7VZV6
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS29935
gene id: 1437453:BN2145_RS29935
uniprot id: A0A0F7VZ78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1437453:BN2145 RS29925
gene id: 1437453:BN2145_RS29925
uniprot id: A0A0F7W2X4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1437453:BN2145 RS03515
gene id: 1437453:BN2145_RS03515
uniprot id: A0A0F7VLT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS07400
gene id: 1437453:BN2145_RS07400
uniprot id: A0A0F7VUL8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1437453:BN2145 RS11675
gene id: 1437453:BN2145_RS11675
uniprot id: A0A0F7VSK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1437453:BN2145 RS11335
gene id: 1437453:BN2145_RS11335
uniprot id: A0A0F7VX04
names: Similarity
messages: Belongs to the CdaR family.

1437453:BN2145 RS06885
gene id: 1437453:BN2145_RS06885
uniprot id: A0A0F7VUE0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1437453:BN2145 RS03455
gene id: 1437453:BN2145_RS03455
uniprot id: A0A0F7VNN4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the UbiD family. YclC subfamily.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS19485
gene id: 1437453:BN2145_RS19485
uniprot id: A0A0F7W229
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1437453:BN2145 RS30935
gene id: 1437453:BN2145_RS30935
uniprot id: A0A0F7W3L9
names: Similarity
messages: Belongs to the peptidase C40 family.

1437453:BN2145 RS08620
gene id: 1437453:BN2145_RS08620
uniprot id: A0A0F7VVC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1437453:BN2145 RS12155
gene id: 1437453:BN2145_RS12155
uniprot id: A0A0F7VSU1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1437453:BN2145 RS25380
gene id: 1437453:BN2145_RS25380
uniprot id: A0A0F7W033
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1437453:BN2145 RS16925
gene id: 1437453:BN2145_RS16925
uniprot id: A0A0F7VS02
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1437453:BN2145 RS11195
gene id: 1437453:BN2145_RS11195
uniprot id: A0A0F7VN40
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1437453:BN2145 RS32230
gene id: 1437453:BN2145_RS32230
uniprot id: A0A0F7W0K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1437453:BN2145 RS12800
gene id: 1437453:BN2145_RS12800
uniprot id: A0A0F7VT59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1437453:BN2145 RS25650
gene id: 1437453:BN2145_RS25650
uniprot id: A0A0F7VWV8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1437453:BN2145 RS19155
gene id: 1437453:BN2145_RS19155
uniprot id: A0A0F7W1X7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1437453:BN2145 RS29090
gene id: 1437453:BN2145_RS29090
uniprot id: A0A0F7VWL1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1437453:BN2145 RS16560
gene id: 1437453:BN2145_RS16560
uniprot id: A0A0F7W0G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS25270
gene id: 1437453:BN2145_RS25270
uniprot id: A0A0F7W001
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1437453:BN2145 RS07875
gene id: 1437453:BN2145_RS07875
uniprot id: A0A0F7VMW0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS20520
gene id: 1437453:BN2145_RS20520
uniprot id: A0A0F7VUA1
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

1437453:BN2145 RS10820
gene id: 1437453:BN2145_RS10820
uniprot id: A0A0F7VV21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1437453:BN2145 RS33300
gene id: 1437453:BN2145_RS33300
uniprot id: A0A0F7W1A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1437453:BN2145 RS07705
gene id: 1437453:BN2145_RS07705
uniprot id: A0A0F7VUU3
names: Similarity
messages: Belongs to the peptidase S66 family.

1437453:BN2145 RS04635
gene id: 1437453:BN2145_RS04635
uniprot id: A0A0F7VT70
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1437453:BN2145 RS24640
gene id: 1437453:BN2145_RS24640
uniprot id: A0A0F7VZP2
names: Similarity
messages: Belongs to the peptidase S8 family.

1437453:BN2145 RS06395
gene id: 1437453:BN2145_RS06395
uniprot id: A0A0F7VSL9
names: Similarity
messages: Belongs to the acyltransferase PapA5 family.

1437453:BN2145 RS21355
gene id: 1437453:BN2145_RS21355
uniprot id: A0A0F7VY43
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1437453:BN2145 RS30010
gene id: 1437453:BN2145_RS30010
uniprot id: A0A0F7VZ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1437453:BN2145 RS26490
gene id: 1437453:BN2145_RS26490
uniprot id: A0A0F7W0W0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1437453:BN2145 RS16055
gene id: 1437453:BN2145_RS16055
uniprot id: A0A0F7VVB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1437453:BN2145 RS26335
gene id: 1437453:BN2145_RS26335
uniprot id: A0A0F7W3G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS19445
gene id: 1437453:BN2145_RS19445
uniprot id: A0A0F7VRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1437453:BN2145 RS12020
gene id: 1437453:BN2145_RS12020
uniprot id: A0A0F7VVN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS09485
gene id: 1437453:BN2145_RS09485
uniprot id: A0A0F7VVT1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

1437453:BN2145 RS14565
gene id: 1437453:BN2145_RS14565
uniprot id: A0A0F7VWZ3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1437453:BN2145 RS24625
gene id: 1437453:BN2145_RS24625
uniprot id: A0A0F7VWA9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS06605
gene id: 1437453:BN2145_RS06605
uniprot id: A0A0F7VPP6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1437453:BN2145 RS14780
gene id: 1437453:BN2145_RS14780
uniprot id: A0A0F7VPI1
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS27555
gene id: 1437453:BN2145_RS27555
uniprot id: A0A0F7W615
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1437453:BN2145 RS14775
gene id: 1437453:BN2145_RS14775
uniprot id: A0A0F7VUI4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1437453:BN2145 RS06390
gene id: 1437453:BN2145_RS06390
uniprot id: A0A0F7VU35
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1437453:BN2145 RS23415
gene id: 1437453:BN2145_RS23415
uniprot id: A0A0F7VVU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1437453:BN2145 RS09490
gene id: 1437453:BN2145_RS09490
uniprot id: A0A0F7VUB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1437453:BN2145 RS24395
gene id: 1437453:BN2145_RS24395
uniprot id: A0A0F7VW94
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1437453:BN2145 RS14175
gene id: 1437453:BN2145_RS14175
uniprot id: A0A0F7VU65
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1437453:BN2145 RS30655
gene id: 1437453:BN2145_RS30655
uniprot id: A0A0F7W5X6
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

1437453:BN2145 RS29820
gene id: 1437453:BN2145_RS29820
uniprot id: A0A0F7W5B7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS10530
gene id: 1437453:BN2145_RS10530
uniprot id: A0A0F7VMW4
names: Subcellular Location Annotation
messages: Cytoplasm

1437453:BN2145 RS02945
gene id: 1437453:BN2145_RS02945
uniprot id: A0A0F7VKV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1437453:BN2145 RS11570
gene id: 1437453:BN2145_RS11570
uniprot id: A0A0F7VSJ0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1437453:BN2145 RS31410
gene id: 1437453:BN2145_RS31410
uniprot id: A0A0F7VY23
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS04410
gene id: 1437453:BN2145_RS04410
uniprot id: A0A0F7VLZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1437453:BN2145 RS24770
gene id: 1437453:BN2145_RS24770
uniprot id: A0A0F7W2K6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1437453:BN2145 RS26350
gene id: 1437453:BN2145_RS26350
uniprot id: A0A0F7VX73
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1437453:BN2145 RS19790
gene id: 1437453:BN2145_RS19790
uniprot id: A0A0F7VZY8
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS21070
gene id: 1437453:BN2145_RS21070
uniprot id: A0A0F7VY02
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1437453:BN2145 RS12735
gene id: 1437453:BN2145_RS12735
uniprot id: A0A0F7VPG0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1437453:BN2145 RS14620
gene id: 1437453:BN2145_RS14620
uniprot id: A0A0F7VUG2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS34490
gene id: 1437453:BN2145_RS34490
uniprot id: A0A0F7W1Y4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS10950
gene id: 1437453:BN2145_RS10950
uniprot id: A0A0F7VWU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1437453:BN2145 RS25140
gene id: 1437453:BN2145_RS25140
uniprot id: A0A0F7VUE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1437453:BN2145 RS21505
gene id: 1437453:BN2145_RS21505
uniprot id: A0A0F7W0Y1
names: Similarity
messages: Belongs to the citrate synthase family.

1437453:BN2145 RS06970
gene id: 1437453:BN2145_RS06970
uniprot id: A0A0F7VPU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

1437453:BN2145 RS06380
gene id: 1437453:BN2145_RS06380
uniprot id: A0A0F7VLK9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS19455
gene id: 1437453:BN2145_RS19455
uniprot id: A0A0F7W224
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1437453:BN2145 RS34760
gene id: 1437453:BN2145_RS34760
uniprot id: A0A0F7VZR2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS00065
gene id: 1437453:BN2145_RS00065
uniprot id: A0A0F7VKY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1437453:BN2145 RS33365
gene id: 1437453:BN2145_RS33365
uniprot id: A0A0F7W7A9
names: Similarity
messages: Belongs to the UPF0166 family.

1437453:BN2145 RS13775
gene id: 1437453:BN2145_RS13775
uniprot id: A0A0F7VQ56
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1437453:BN2145 RS12525
gene id: 1437453:BN2145_RS12525
uniprot id: A0A0F7VNH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1437453:BN2145 RS21990
gene id: 1437453:BN2145_RS21990
uniprot id: A0A0F7VYB7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1437453:BN2145 RS25390
gene id: 1437453:BN2145_RS25390
uniprot id: A0A0F7VWP1
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS14910
gene id: 1437453:BN2145_RS14910
uniprot id: A0A0F7VQN6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1437453:BN2145 RS14865
gene id: 1437453:BN2145_RS14865
uniprot id: A0A0F7VZL9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS12590
gene id: 1437453:BN2145_RS12590
uniprot id: A0A0F7VXU5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS24015
gene id: 1437453:BN2145_RS24015
uniprot id: A0A0F7W291
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS20185
gene id: 1437453:BN2145_RS20185
uniprot id: A0A0F7VU10
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1437453:BN2145 RS24685
gene id: 1437453:BN2145_RS24685
uniprot id: A0A0F7W2J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1437453:BN2145 RS18725
gene id: 1437453:BN2145_RS18725
uniprot id: A0A0F7VR22
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS17830
gene id: 1437453:BN2145_RS17830
uniprot id: A0A0F7W169
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1437453:BN2145 RS28075
gene id: 1437453:BN2145_RS28075
uniprot id: A0A0F7W685
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437453:BN2145 RS09305
gene id: 1437453:BN2145_RS09305
uniprot id: A0A0F7VMG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1437453:BN2145 RS28520
gene id: 1437453:BN2145_RS28520
uniprot id: A0A0F7W221
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1437453:BN2145 RS16040
gene id: 1437453:BN2145_RS16040
uniprot id: A0A0F7VRH2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS22295
gene id: 1437453:BN2145_RS22295
uniprot id: A0A0F7VVA5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS03690
gene id: 1437453:BN2145_RS03690
uniprot id: A0A0F7VSR1
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS05980
gene id: 1437453:BN2145_RS05980
uniprot id: A0A0F7VPG2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS04490
gene id: 1437453:BN2145_RS04490
uniprot id: A0A0F7VT40
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS01460
gene id: 1437453:BN2145_RS01460
uniprot id: A0A0F7VKP9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS26495
gene id: 1437453:BN2145_RS26495
uniprot id: A0A0F7VV47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1437453:BN2145 RS32135
gene id: 1437453:BN2145_RS32135
uniprot id: A0A0F7W8D1
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

1437453:BN2145 RS17210
gene id: 1437453:BN2145_RS17210
uniprot id: A0A0F7VVX7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437453:BN2145 RS15120
gene id: 1437453:BN2145_RS15120
uniprot id: A0A0F7VQS7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1437453:BN2145 RS34150
gene id: 1437453:BN2145_RS34150
uniprot id: A0A0F7W9I9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1437453:BN2145 RS20205
gene id: 1437453:BN2145_RS20205
uniprot id: A0A0F7VRS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS03980
gene id: 1437453:BN2145_RS03980
uniprot id: A0A0F7VLX7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1437453:BN2145 RS15515
gene id: 1437453:BN2145_RS15515
uniprot id: A0A0F7VPQ6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1437453:BN2145 RS21160
gene id: 1437453:BN2145_RS21160
uniprot id: A0A0F7W2Z5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS17880
gene id: 1437453:BN2145_RS17880
uniprot id: A0A0F7W178
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS27230
gene id: 1437453:BN2145_RS27230
uniprot id: A0A0F7W5S9
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1437453:BN2145 RS12465
gene id: 1437453:BN2145_RS12465
uniprot id: A0A0F7VVW8
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS26745
gene id: 1437453:BN2145_RS26745
uniprot id: A0A0F7VV89
names: Similarity
messages: Belongs to the arsA ATPase family.

1437453:BN2145 RS16225
gene id: 1437453:BN2145_RS16225
uniprot id: A0A0F7VY15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1437453:BN2145 RS12865
gene id: 1437453:BN2145_RS12865
uniprot id: A0A0F7VXZ9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1437453:BN2145 RS20675
gene id: 1437453:BN2145_RS20675
uniprot id: A0A0F7VUC2
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1437453:BN2145 RS26825
gene id: 1437453:BN2145_RS26825
uniprot id: A0A0F7VXI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1437453:BN2145 RS16240
gene id: 1437453:BN2145_RS16240
uniprot id: A0A0F7VRL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1437453:BN2145 RS30050
gene id: 1437453:BN2145_RS30050
uniprot id: A0A0F7W2Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

1437453:BN2145 RS25555
gene id: 1437453:BN2145_RS25555
uniprot id: A0A0F7W2Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS10550
gene id: 1437453:BN2145_RS10550
uniprot id: A0A0F7VS05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1437453:BN2145 RS27680
gene id: 1437453:BN2145_RS27680
uniprot id: A0A0F7W625
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS28030
gene id: 1437453:BN2145_RS28030
uniprot id: A0A0F7W481
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1437453:BN2145 RS30180
gene id: 1437453:BN2145_RS30180
uniprot id: A0A0F7VZB6
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS30030
gene id: 1437453:BN2145_RS30030
uniprot id: A0A0F7VX86
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1437453:BN2145 RS31805
gene id: 1437453:BN2145_RS31805
uniprot id: A0A0F7VY92
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1437453:BN2145 RS01840
gene id: 1437453:BN2145_RS01840
uniprot id: A0A0F7VQ74
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS16780
gene id: 1437453:BN2145_RS16780
uniprot id: A0A0F7VRX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS08105
gene id: 1437453:BN2145_RS08105
uniprot id: A0A0F7VMZ7
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1437453:BN2145 RS16705
gene id: 1437453:BN2145_RS16705
uniprot id: A0A0F7VRW7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1437453:BN2145 RS16430
gene id: 1437453:BN2145_RS16430
uniprot id: A0A0F7VY85
names: Similarity
messages: Belongs to the UPF0336 family.

1437453:BN2145 RS11600
gene id: 1437453:BN2145_RS11600
uniprot id: A0A0F7VN91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

1437453:BN2145 RS21065
gene id: 1437453:BN2145_RS21065
uniprot id: A0A0F7W0N1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1437453:BN2145 RS17270
gene id: 1437453:BN2145_RS17270
uniprot id: A0A0F7VYM0
names: Similarity
messages: Belongs to the histone deacetylase family.

1437453:BN2145 RS11680
gene id: 1437453:BN2145_RS11680
uniprot id: A0A0F7VN97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1437453:BN2145 RS31345
gene id: 1437453:BN2145_RS31345
uniprot id: A0A0F7W7Z5
names: Similarity
messages: Belongs to the tannase family.

1437453:BN2145 RS35125
gene id: 1437453:BN2145_RS35125
uniprot id: A0A0F7VZY7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1437453:BN2145 RS17190
gene id: 1437453:BN2145_RS17190
uniprot id: A0A0F7VQD8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS16180
gene id: 1437453:BN2145_RS16180
uniprot id: A0A0F7VVE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1437453:BN2145 RS18055
gene id: 1437453:BN2145_RS18055
uniprot id: A0A0F7VWG2
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1437453:BN2145 RS05730
gene id: 1437453:BN2145_RS05730
uniprot id: A0A0F7VPE3
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1437453:BN2145 RS16965
gene id: 1437453:BN2145_RS16965
uniprot id: A0A0F7VVT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1437453:BN2145 RS31990
gene id: 1437453:BN2145_RS31990
uniprot id: A0A0F7VYB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS29280
gene id: 1437453:BN2145_RS29280
uniprot id: A0A0F7W506
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1437453:BN2145 RS10855
gene id: 1437453:BN2145_RS10855
uniprot id: A0A0F7VN07
names: Similarity
messages: Belongs to the Dps family.

1437453:BN2145 RS02370
gene id: 1437453:BN2145_RS02370
uniprot id: A0A0F7VQG6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS27925
gene id: 1437453:BN2145_RS27925
uniprot id: A0A0F7VY35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1437453:BN2145 RS07270
gene id: 1437453:BN2145_RS07270
uniprot id: A0A0F7VPY8
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS21345
gene id: 1437453:BN2145_RS21345
uniprot id: A0A0F7W318
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS09520
gene id: 1437453:BN2145_RS09520
uniprot id: A0A0F7VRA2
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1437453:BN2145 RS00690
gene id: 1437453:BN2145_RS00690
uniprot id: A0A0F7VL53
names: Similarity
messages: Belongs to the thioredoxin family.

1437453:BN2145 RS20125
gene id: 1437453:BN2145_RS20125
uniprot id: A0A0F7VRR2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1437453:BN2145 RS26990
gene id: 1437453:BN2145_RS26990
uniprot id: A0A0F7W3R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1437453:BN2145 RS11860
gene id: 1437453:BN2145_RS11860
uniprot id: A0A0F7VP40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1437453:BN2145 RS08985
gene id: 1437453:BN2145_RS08985
uniprot id: A0A0F7VVJ5
names: Similarity
messages: Belongs to the YciI family.

1437453:BN2145 RS24795
gene id: 1437453:BN2145_RS24795
uniprot id: A0A0F7W2K8
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1437453:BN2145 RS20085
gene id: 1437453:BN2145_RS20085
uniprot id: A0A0F7VRQ3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1437453:BN2145 RS27310
gene id: 1437453:BN2145_RS27310
uniprot id: A0A0F7W3V3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1437453:BN2145 RS30645
gene id: 1437453:BN2145_RS30645
uniprot id: A0A0F7VXL2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS07540
gene id: 1437453:BN2145_RS07540
uniprot id: A0A0F7VMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS24800
gene id: 1437453:BN2145_RS24800
uniprot id: A0A0F7VZR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1437453:BN2145 RS12640
gene id: 1437453:BN2145_RS12640
uniprot id: A0A0F7VXV6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1437453:BN2145 RS21225
gene id: 1437453:BN2145_RS21225
uniprot id: A0A0F7W302
names: Similarity
messages: Belongs to the CutC family.

1437453:BN2145 RS22580
gene id: 1437453:BN2145_RS22580
uniprot id: A0A0F7W3P5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1437453:BN2145 RS26110
gene id: 1437453:BN2145_RS26110
uniprot id: A0A0F7VX38
names: Similarity
messages: Belongs to the UPF0246 family.

1437453:BN2145 RS31155
gene id: 1437453:BN2145_RS31155
uniprot id: A0A0F7W3P6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS01140
gene id: 1437453:BN2145_RS01140
uniprot id: A0A0F7VPZ1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1437453:BN2145 RS27035
gene id: 1437453:BN2145_RS27035
uniprot id: A0A0F7W5R4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1437453:BN2145 RS11200
gene id: 1437453:BN2145_RS11200
uniprot id: A0A0F7VNX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1437453:BN2145 RS06435
gene id: 1437453:BN2145_RS06435
uniprot id: A0A0F7VMF4
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1437453:BN2145 RS13025
gene id: 1437453:BN2145_RS13025
uniprot id: A0A0F7VPR4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1437453:BN2145 RS11225
gene id: 1437453:BN2145_RS11225
uniprot id: A0A0F7VN43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1437453:BN2145 RS33085
gene id: 1437453:BN2145_RS33085
uniprot id: A0A0F7W735
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS28225
gene id: 1437453:BN2145_RS28225
uniprot id: A0A0F7W6A4
names: Similarity
messages: Belongs to the peptidase S8 family.

1437453:BN2145 RS04140
gene id: 1437453:BN2145_RS04140
uniprot id: A0A0F7VR89
names: Similarity
messages: In the N-terminal section; belongs to the cytochrome P450 family.

1437453:BN2145 RS08270
gene id: 1437453:BN2145_RS08270
uniprot id: A0A0F7VTJ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1437453:BN2145 RS00935
gene id: 1437453:BN2145_RS00935
uniprot id: A0A0F7VRF2
names: Similarity
messages: Belongs to the ParB family.

1437453:BN2145 RS28755
gene id: 1437453:BN2145_RS28755
uniprot id: A0A0F7VWG4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS29475
gene id: 1437453:BN2145_RS29475
uniprot id: A0A0F7W6T9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437453:BN2145 RS20535
gene id: 1437453:BN2145_RS20535
uniprot id: A0A0F7VXR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1437453:BN2145 RS09655
gene id: 1437453:BN2145_RS09655
uniprot id: A0A0F7VW09
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1437453:BN2145 RS30970
gene id: 1437453:BN2145_RS30970
uniprot id: A0A0F7W010
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1437453:BN2145 RS14425
gene id: 1437453:BN2145_RS14425
uniprot id: A0A0F7VUB9
names: Similarity
messages: Belongs to the LOG family.

1437453:BN2145 RS05450
gene id: 1437453:BN2145_RS05450
uniprot id: A0A0F7VLC8
names: Similarity
messages: Belongs to the peptidase S8 family.

1437453:BN2145 RS23585
gene id: 1437453:BN2145_RS23585
uniprot id: A0A0F7W4E9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS14665
gene id: 1437453:BN2145_RS14665
uniprot id: A0A0F7VX10
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1437453:BN2145 RS31400
gene id: 1437453:BN2145_RS31400
uniprot id: A0A0F7W6E6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1437453:BN2145 RS27410
gene id: 1437453:BN2145_RS27410
uniprot id: A0A0F7W5W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1437453:BN2145 RS11595
gene id: 1437453:BN2145_RS11595
uniprot id: A0A0F7VSJ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1437453:BN2145 RS29900
gene id: 1437453:BN2145_RS29900
uniprot id: A0A0F7W2X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1437453:BN2145 RS22820
gene id: 1437453:BN2145_RS22820
uniprot id: A0A0F7W1K7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1437453:BN2145 RS16110
gene id: 1437453:BN2145_RS16110
uniprot id: A0A0F7VPY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1437453:BN2145 RS09360
gene id: 1437453:BN2145_RS09360
uniprot id: A0A0F7VNE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS16135
gene id: 1437453:BN2145_RS16135
uniprot id: A0A0F7VRJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1437453:BN2145 RS19705
gene id: 1437453:BN2145_RS19705
uniprot id: A0A0F7VTT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1437453:BN2145 RS09205
gene id: 1437453:BN2145_RS09205
uniprot id: A0A0F7VMF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS31875
gene id: 1437453:BN2145_RS31875
uniprot id: A0A0F7W429
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1437453:BN2145 RS27300
gene id: 1437453:BN2145_RS27300
uniprot id: A0A0F7VXP2
names: Similarity
messages: Belongs to the group II decarboxylase family.

1437453:BN2145 RS15265
gene id: 1437453:BN2145_RS15265
uniprot id: A0A0F7VQX7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS07505
gene id: 1437453:BN2145_RS07505
uniprot id: A0A0F7VQ39
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS34870
gene id: 1437453:BN2145_RS34870
uniprot id: A0A0F7W853
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS20705
gene id: 1437453:BN2145_RS20705
uniprot id: A0A0F7W2S1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS06915
gene id: 1437453:BN2145_RS06915
uniprot id: A0A0F7VSW7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1437453:BN2145 RS30950
gene id: 1437453:BN2145_RS30950
uniprot id: A0A0F7W7R0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1437453:BN2145 RS35035
gene id: 1437453:BN2145_RS35035
uniprot id: A0A0F7W273
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1437453:BN2145 RS07085
gene id: 1437453:BN2145_RS07085
uniprot id: A0A0F7VSZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1437453:BN2145 RS26090
gene id: 1437453:BN2145_RS26090
uniprot id: A0A0F7W5H2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1437453:BN2145 RS35020
gene id: 1437453:BN2145_RS35020
uniprot id: A0A0F7W888
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1437453:BN2145 RS24810
gene id: 1437453:BN2145_RS24810
uniprot id: A0A0F7VWD7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS08075
gene id: 1437453:BN2145_RS08075
uniprot id: A0A0F7VM27
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1437453:BN2145 RS15920
gene id: 1437453:BN2145_RS15920
uniprot id: A0A0F7VRF3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1437453:BN2145 RS26450
gene id: 1437453:BN2145_RS26450
uniprot id: A0A0F7VXB5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1437453:BN2145 RS12015
gene id: 1437453:BN2145_RS12015
uniprot id: A0A0F7VXF9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1437453:BN2145 RS29595
gene id: 1437453:BN2145_RS29595
uniprot id: A0A0F7VWT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS22565
gene id: 1437453:BN2145_RS22565
uniprot id: A0A0F7VYJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS21740
gene id: 1437453:BN2145_RS21740
uniprot id: A0A0F7VY82
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS03610
gene id: 1437453:BN2145_RS03610
uniprot id: A0A0F7VLU0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS14330
gene id: 1437453:BN2145_RS14330
uniprot id: A0A0F7VPB1
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS12435
gene id: 1437453:BN2145_RS12435
uniprot id: A0A0F7VXQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1437453:BN2145 RS21110
gene id: 1437453:BN2145_RS21110
uniprot id: A0A0F7W2Y8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1437453:BN2145 RS34905
gene id: 1437453:BN2145_RS34905
uniprot id: A0A0F7VZU1
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS04255
gene id: 1437453:BN2145_RS04255
uniprot id: A0A0F7VLZ1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1437453:BN2145 RS09830
gene id: 1437453:BN2145_RS09830
uniprot id: A0A0F7VUJ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS35000
gene id: 1437453:BN2145_RS35000
uniprot id: A0A0F7W603
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS12080
gene id: 1437453:BN2145_RS12080
uniprot id: A0A0F7VP73
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1437453:BN2145 RS11640
gene id: 1437453:BN2145_RS11640
uniprot id: A0A0F7VX74
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1437453:BN2145 RS03385
gene id: 1437453:BN2145_RS03385
uniprot id: A0A0F7VKY4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1437453:BN2145 RS15310
gene id: 1437453:BN2145_RS15310
uniprot id: A0A0F7VPM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS17160
gene id: 1437453:BN2145_RS17160
uniprot id: A0A0F7VVW9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437453:BN2145 RS10145
gene id: 1437453:BN2145_RS10145
uniprot id: A0A0F7VUR6
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1437453:BN2145 RS29375
gene id: 1437453:BN2145_RS29375
uniprot id: A0A0F7W6T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1437453:BN2145 RS06195
gene id: 1437453:BN2145_RS06195
uniprot id: A0A0F7VMC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1437453:BN2145 RS29910
gene id: 1437453:BN2145_RS29910
uniprot id: A0A0F7VZ76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1437453:BN2145 RS32600
gene id: 1437453:BN2145_RS32600
uniprot id: A0A0F7VYR2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS20925
gene id: 1437453:BN2145_RS20925
uniprot id: A0A0F7VUM2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1437453:BN2145 RS32095
gene id: 1437453:BN2145_RS32095
uniprot id: A0A0F7W464
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1437453:BN2145 RS32745
gene id: 1437453:BN2145_RS32745
uniprot id: A0A0F7W4K0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS29190
gene id: 1437453:BN2145_RS29190
uniprot id: A0A0F7VWM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

1437453:BN2145 RS29600
gene id: 1437453:BN2145_RS29600
uniprot id: A0A0F7VZ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS28440
gene id: 1437453:BN2145_RS28440
uniprot id: A0A0F7W4P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS20070
gene id: 1437453:BN2145_RS20070
uniprot id: A0A0F7W2B8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1437453:BN2145 RS21565
gene id: 1437453:BN2145_RS21565
uniprot id: A0A0F7VSJ1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1437453:BN2145 RS07180
gene id: 1437453:BN2145_RS07180
uniprot id: A0A0F7VMN5
names: Similarity
messages: Belongs to the TPP enzyme family.

1437453:BN2145 RS07140
gene id: 1437453:BN2145_RS07140
uniprot id: A0A0F7VPX3
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS15600
gene id: 1437453:BN2145_RS15600
uniprot id: A0A0F7W055
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS19370
gene id: 1437453:BN2145_RS19370
uniprot id: A0A0F7W213
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1437453:BN2145 RS25925
gene id: 1437453:BN2145_RS25925
uniprot id: A0A0F7W3A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1437453:BN2145 RS31445
gene id: 1437453:BN2145_RS31445
uniprot id: A0A0F7W821
names: Similarity
messages: Belongs to the UPF0047 family.

1437453:BN2145 RS29870
gene id: 1437453:BN2145_RS29870
uniprot id: A0A0F7W5C5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1437453:BN2145 RS23370
gene id: 1437453:BN2145_RS23370
uniprot id: A0A0F7W4B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1437453:BN2145 RS20715
gene id: 1437453:BN2145_RS20715
uniprot id: A0A0F7VXT3
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1437453:BN2145 RS11315
gene id: 1437453:BN2145_RS11315
uniprot id: A0A0F7VV98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS14720
gene id: 1437453:BN2145_RS14720
uniprot id: A0A0F7VUH7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1437453:BN2145 RS04055
gene id: 1437453:BN2145_RS04055
uniprot id: A0A0F7VLY2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1437453:BN2145 RS28270
gene id: 1437453:BN2145_RS28270
uniprot id: A0A0F7VYD3
names: Similarity
messages: Belongs to the peptidase U62 family.

1437453:BN2145 RS17540
gene id: 1437453:BN2145_RS17540
uniprot id: A0A0F7W117
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS22485
gene id: 1437453:BN2145_RS22485
uniprot id: A0A0F7W1G4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS02105
gene id: 1437453:BN2145_RS02105
uniprot id: A0A0F7VN30
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1437453:BN2145 RS12900
gene id: 1437453:BN2145_RS12900
uniprot id: A0A0F7VNM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1437453:BN2145 RS11845
gene id: 1437453:BN2145_RS11845
uniprot id: A0A0F7VVK3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1437453:BN2145 RS26665
gene id: 1437453:BN2145_RS26665
uniprot id: A0A0F7W0Y8
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS22010
gene id: 1437453:BN2145_RS22010
uniprot id: A0A0F7VYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1437453:BN2145 RS27910
gene id: 1437453:BN2145_RS27910
uniprot id: A0A0F7W458
names: Similarity
messages: Belongs to the IlvD/Edd family.

1437453:BN2145 RS22440
gene id: 1437453:BN2145_RS22440
uniprot id: A0A0F7VYI2
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1437453:BN2145 RS07880
gene id: 1437453:BN2145_RS07880
uniprot id: A0A0F7VUX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1437453:BN2145 RS05520
gene id: 1437453:BN2145_RS05520
uniprot id: A0A0F7VS52
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS23400
gene id: 1437453:BN2145_RS23400
uniprot id: A0A0F7W1Z2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS10815
gene id: 1437453:BN2145_RS10815
uniprot id: A0A0F7VWT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1437453:BN2145 RS27080
gene id: 1437453:BN2145_RS27080
uniprot id: A0A0F7VXL1
names: Subcellular Location Annotation
messages: Cytoplasm

1437453:BN2145 RS28745
gene id: 1437453:BN2145_RS28745
uniprot id: A0A0F7W4U0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1437453:BN2145 RS25075
gene id: 1437453:BN2145_RS25075
uniprot id: A0A0F7VWJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1437453:BN2145 RS04715
gene id: 1437453:BN2145_RS04715
uniprot id: A0A0F7VRL3
names: Similarity
messages: Belongs to the UPF0098 family.

1437453:BN2145 RS27770
gene id: 1437453:BN2145_RS27770
uniprot id: A0A0F7VVZ5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1437453:BN2145 RS19195
gene id: 1437453:BN2145_RS19195
uniprot id: A0A0F7VR76
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS31705
gene id: 1437453:BN2145_RS31705
uniprot id: A0A0F7W3Z9
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1437453:BN2145 RS23965
gene id: 1437453:BN2145_RS23965
uniprot id: A0A0F7W284
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS19610
gene id: 1437453:BN2145_RS19610
uniprot id: A0A0F7W252
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1437453:BN2145 RS27125
gene id: 1437453:BN2145_RS27125
uniprot id: A0A0F7VXL5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS21725
gene id: 1437453:BN2145_RS21725
uniprot id: A0A0F7VUV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1437453:BN2145 RS16250
gene id: 1437453:BN2145_RS16250
uniprot id: A0A0F7VY21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm

1437453:BN2145 RS18385
gene id: 1437453:BN2145_RS18385
uniprot id: A0A0F7VZ97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1437453:BN2145 RS17605
gene id: 1437453:BN2145_RS17605
uniprot id: A0A0F7VQH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1437453:BN2145 RS29400
gene id: 1437453:BN2145_RS29400
uniprot id: A0A0F7W6T5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS21975
gene id: 1437453:BN2145_RS21975
uniprot id: A0A0F7VYB3
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS18230
gene id: 1437453:BN2145_RS18230
uniprot id: A0A0F7W1N5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS11645
gene id: 1437453:BN2145_RS11645
uniprot id: A0A0F7VVH5
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1437453:BN2145 RS16385
gene id: 1437453:BN2145_RS16385
uniprot id: A0A0F7VVG1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1437453:BN2145 RS17150
gene id: 1437453:BN2145_RS17150
uniprot id: A0A0F7W0V2
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1437453:BN2145 RS07730
gene id: 1437453:BN2145_RS07730
uniprot id: A0A0F7VUU8
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS28770
gene id: 1437453:BN2145_RS28770
uniprot id: A0A0F7W4U3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS12535
gene id: 1437453:BN2145_RS12535
uniprot id: A0A0F7VXT4
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1437453:BN2145 RS11260
gene id: 1437453:BN2145_RS11260
uniprot id: A0A0F7VWZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1437453:BN2145 RS28480
gene id: 1437453:BN2145_RS28480
uniprot id: A0A0F7VYK8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS13900
gene id: 1437453:BN2145_RS13900
uniprot id: A0A0F7VQ67
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1437453:BN2145 RS16515
gene id: 1437453:BN2145_RS16515
uniprot id: A0A0F7VY93
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS29895
gene id: 1437453:BN2145_RS29895
uniprot id: A0A0F7W5C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1437453:BN2145 RS07910
gene id: 1437453:BN2145_RS07910
uniprot id: A0A0F7VTE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1437453:BN2145 RS21240
gene id: 1437453:BN2145_RS21240
uniprot id: A0A0F7VSE2
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1437453:BN2145 RS32005
gene id: 1437453:BN2145_RS32005
uniprot id: A0A0F7W6K8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1437453:BN2145 RS01605
gene id: 1437453:BN2145_RS01605
uniprot id: A0A0F7VKQ5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS34885
gene id: 1437453:BN2145_RS34885
uniprot id: A0A0F7W257
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS21390
gene id: 1437453:BN2145_RS21390
uniprot id: A0A0F7VUR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS03155
gene id: 1437453:BN2145_RS03155
uniprot id: A0A0F7VLQ7
names: Similarity
messages: Belongs to the thioesterase family.

1437453:BN2145 RS02910
gene id: 1437453:BN2145_RS02910
uniprot id: A0A0F7VQP3
names: Similarity
messages: Belongs to the PrpD family.

1437453:BN2145 RS11510
gene id: 1437453:BN2145_RS11510
uniprot id: A0A0F7VX52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1437453:BN2145 RS11445
gene id: 1437453:BN2145_RS11445
uniprot id: A0A0F7VSH6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1437453:BN2145 RS10980
gene id: 1437453:BN2145_RS10980
uniprot id: A0A0F7VV41
names: Similarity
messages: Belongs to the peptidase M16 family.

1437453:BN2145 RS04945
gene id: 1437453:BN2145_RS04945
uniprot id: A0A0F7VRP7
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1437453:BN2145 RS15565
gene id: 1437453:BN2145_RS15565
uniprot id: A0A0F7VPS2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS24785
gene id: 1437453:BN2145_RS24785
uniprot id: A0A0F7VWD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1437453:BN2145 RS22790
gene id: 1437453:BN2145_RS22790
uniprot id: A0A0F7W3W8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1437453:BN2145 RS09290
gene id: 1437453:BN2145_RS09290
uniprot id: A0A0F7VVQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted

1437453:BN2145 RS28600
gene id: 1437453:BN2145_RS28600
uniprot id: A0A0F7W236
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1437453:BN2145 RS23710
gene id: 1437453:BN2145_RS23710
uniprot id: A0A0F7VTM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS04565
gene id: 1437453:BN2145_RS04565
uniprot id: A0A0F7VT52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS14995
gene id: 1437453:BN2145_RS14995
uniprot id: A0A0F7VX87
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS30230
gene id: 1437453:BN2145_RS30230
uniprot id: A0A0F7VZC5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS25005
gene id: 1437453:BN2145_RS25005
uniprot id: A0A0F7W2Q7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1437453:BN2145 RS24470
gene id: 1437453:BN2145_RS24470
uniprot id: A0A0F7VU36
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1437453:BN2145 RS06670
gene id: 1437453:BN2145_RS06670
uniprot id: A0A0F7VSS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS07815
gene id: 1437453:BN2145_RS07815
uniprot id: A0A0F7VQA4
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1437453:BN2145 RS08765
gene id: 1437453:BN2145_RS08765
uniprot id: A0A0F7VN78
names: Similarity
messages: Belongs to the NodU/CmcH family.

1437453:BN2145 RS15930
gene id: 1437453:BN2145_RS15930
uniprot id: A0A0F7VXX0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1437453:BN2145 RS25720
gene id: 1437453:BN2145_RS25720
uniprot id: A0A0F7VUP0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1437453:BN2145 RS09255
gene id: 1437453:BN2145_RS09255
uniprot id: A0A0F7VMF5
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

1437453:BN2145 RS10845
gene id: 1437453:BN2145_RS10845
uniprot id: A0A0F7VV24
names: Similarity
messages: Belongs to the AHA1 family.

1437453:BN2145 RS16300
gene id: 1437453:BN2145_RS16300
uniprot id: A0A0F7VVF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1437453:BN2145 RS17600
gene id: 1437453:BN2145_RS17600
uniprot id: A0A0F7VW61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1437453:BN2145 RS22050
gene id: 1437453:BN2145_RS22050
uniprot id: A0A0F7W3C4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1437453:BN2145 RS04695
gene id: 1437453:BN2145_RS04695
uniprot id: A0A0F7VP12
names: Similarity
messages: Belongs to the archease family.

1437453:BN2145 RS08255
gene id: 1437453:BN2145_RS08255
uniprot id: A0A0F7VM41
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1437453:BN2145 RS34285
gene id: 1437453:BN2145_RS34285
uniprot id: A0A0F7W5H8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS00320
gene id: 1437453:BN2145_RS00320
uniprot id: A0A0F7VL15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1437453:BN2145 RS33965
gene id: 1437453:BN2145_RS33965
uniprot id: A0A0F7VZC4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS15190
gene id: 1437453:BN2145_RS15190
uniprot id: A0A0F7VQU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1437453:BN2145 RS22845
gene id: 1437453:BN2145_RS22845
uniprot id: A0A0F7W1K8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1437453:BN2145 RS28085
gene id: 1437453:BN2145_RS28085
uniprot id: A0A0F7W1L5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437453:BN2145 RS16035
gene id: 1437453:BN2145_RS16035
uniprot id: A0A0F7VPX4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1437453:BN2145 RS24085
gene id: 1437453:BN2145_RS24085
uniprot id: A0A0F7W2A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1437453:BN2145 RS33665
gene id: 1437453:BN2145_RS33665
uniprot id: A0A0F7W9B6
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS17165
gene id: 1437453:BN2145_RS17165
uniprot id: A0A0F7VQD5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1437453:BN2145 RS11530
gene id: 1437453:BN2145_RS11530
uniprot id: A0A0F7VP11
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1437453:BN2145 RS18095
gene id: 1437453:BN2145_RS18095
uniprot id: A0A0F7W1B5
names: Similarity
messages: Belongs to the NodU/CmcH family.

1437453:BN2145 RS21120
gene id: 1437453:BN2145_RS21120
uniprot id: A0A0F7VY10
names: Subcellular Location Annotation
messages: Cytoplasm

1437453:BN2145 RS05425
gene id: 1437453:BN2145_RS05425
uniprot id: A0A0F7VLC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1437453:BN2145 RS12305
gene id: 1437453:BN2145_RS12305
uniprot id: A0A0F7VNF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1437453:BN2145 RS12980
gene id: 1437453:BN2145_RS12980
uniprot id: A0A0F7VY49
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1437453:BN2145 RS16725
gene id: 1437453:BN2145_RS16725
uniprot id: A0A0F7VQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1437453:BN2145 RS17090
gene id: 1437453:BN2145_RS17090
uniprot id: A0A0F7VVV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1437453:BN2145 RS21485
gene id: 1437453:BN2145_RS21485
uniprot id: A0A0F7VY61
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS15835
gene id: 1437453:BN2145_RS15835
uniprot id: A0A0F7VV79
names: Similarity
messages: Belongs to the peptidase C40 family.

1437453:BN2145 RS04550
gene id: 1437453:BN2145_RS04550
uniprot id: A0A0F7VNY9
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

1437453:BN2145 RS23150
gene id: 1437453:BN2145_RS23150
uniprot id: A0A0F7VYV1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS33575
gene id: 1437453:BN2145_RS33575
uniprot id: A0A0F7W584
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS33220
gene id: 1437453:BN2145_RS33220
uniprot id: A0A0F7VYZ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS04995
gene id: 1437453:BN2145_RS04995
uniprot id: A0A0F7VP41
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1437453:BN2145 RS25680
gene id: 1437453:BN2145_RS25680
uniprot id: A0A0F7W583
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1437453:BN2145 RS27665
gene id: 1437453:BN2145_RS27665
uniprot id: A0A0F7W1F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1437453:BN2145 RS07145
gene id: 1437453:BN2145_RS07145
uniprot id: A0A0F7VLS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS09380
gene id: 1437453:BN2145_RS09380
uniprot id: A0A0F7VMI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1437453:BN2145 RS26410
gene id: 1437453:BN2145_RS26410
uniprot id: A0A0F7W3H1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1437453:BN2145 RS23875
gene id: 1437453:BN2145_RS23875
uniprot id: A0A0F7VTQ1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS27705
gene id: 1437453:BN2145_RS27705
uniprot id: A0A0F7W626
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1437453:BN2145 RS30025
gene id: 1437453:BN2145_RS30025
uniprot id: A0A0F7W2Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1437453:BN2145 RS25490
gene id: 1437453:BN2145_RS25490
uniprot id: A0A0F7VUI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

1437453:BN2145 RS08530
gene id: 1437453:BN2145_RS08530
uniprot id: A0A0F7VQR6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1437453:BN2145 RS28065
gene id: 1437453:BN2145_RS28065
uniprot id: A0A0F7VW48
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437453:BN2145 RS24030
gene id: 1437453:BN2145_RS24030
uniprot id: A0A0F7VW50
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1437453:BN2145 RS15040
gene id: 1437453:BN2145_RS15040
uniprot id: A0A0F7VZP0
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1437453:BN2145 RS25200
gene id: 1437453:BN2145_RS25200
uniprot id: A0A0F7VUE7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1437453:BN2145 RS08200
gene id: 1437453:BN2145_RS08200
uniprot id: A0A0F7VQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS27540
gene id: 1437453:BN2145_RS27540
uniprot id: A0A0F7W1D6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1437453:BN2145 RS24165
gene id: 1437453:BN2145_RS24165
uniprot id: A0A0F7W2A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS14690
gene id: 1437453:BN2145_RS14690
uniprot id: A0A0F7VX14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1437453:BN2145 RS32190
gene id: 1437453:BN2145_RS32190
uniprot id: A0A0F7W6N6
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS06585
gene id: 1437453:BN2145_RS06585
uniprot id: A0A0F7VLM8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1437453:BN2145 RS38330
gene id: 1437453:BN2145_RS38330
uniprot id: A0A0F7VPH1
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1437453:BN2145 RS15290
gene id: 1437453:BN2145_RS15290
uniprot id: A0A0F7VR10
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS14800
gene id: 1437453:BN2145_RS14800
uniprot id: A0A0F7VUI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1437453:BN2145 RS29370
gene id: 1437453:BN2145_RS29370
uniprot id: A0A0F7VYY1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1437453:BN2145 RS19440
gene id: 1437453:BN2145_RS19440
uniprot id: A0A0F7VXA7
names: Similarity
messages: Belongs to the UPF0232 family.

1437453:BN2145 RS29675
gene id: 1437453:BN2145_RS29675
uniprot id: A0A0F7VZ32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1437453:BN2145 RS16505
gene id: 1437453:BN2145_RS16505
uniprot id: A0A0F7VQ38
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS03350
gene id: 1437453:BN2145_RS03350
uniprot id: A0A0F7VQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS34040
gene id: 1437453:BN2145_RS34040
uniprot id: A0A0F7VZD8
names: Similarity
messages: Belongs to the universal stress protein A family.

1437453:BN2145 RS04525
gene id: 1437453:BN2145_RS04525
uniprot id: A0A0F7VNY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS23675
gene id: 1437453:BN2145_RS23675
uniprot id: A0A0F7VZ50
names: Similarity
messages: Belongs to the peptidase C40 family.

1437453:BN2145 RS30045
gene id: 1437453:BN2145_RS30045
uniprot id: A0A0F7W5F9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS22320
gene id: 1437453:BN2145_RS22320
uniprot id: A0A0F7VVA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1437453:BN2145 RS10090
gene id: 1437453:BN2145_RS10090
uniprot id: A0A0F7VW78
names: Similarity
messages: Belongs to the amidinotransferase family.

1437453:BN2145 RS06545
gene id: 1437453:BN2145_RS06545
uniprot id: A0A0F7VU62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1437453:BN2145 RS16755
gene id: 1437453:BN2145_RS16755
uniprot id: A0A0F7VRX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS05760
gene id: 1437453:BN2145_RS05760
uniprot id: A0A0F7VS88
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS07925
gene id: 1437453:BN2145_RS07925
uniprot id: A0A0F7VMX4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1437453:BN2145 RS06840
gene id: 1437453:BN2145_RS06840
uniprot id: A0A0F7VSV4
names: Similarity
messages: Belongs to the DDAH family.

1437453:BN2145 RS25375
gene id: 1437453:BN2145_RS25375
uniprot id: A0A0F7W2W7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1437453:BN2145 RS28465
gene id: 1437453:BN2145_RS28465
uniprot id: A0A0F7W4P7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS15155
gene id: 1437453:BN2145_RS15155
uniprot id: A0A0F7VXB1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1437453:BN2145 RS30020
gene id: 1437453:BN2145_RS30020
uniprot id: A0A0F7W5F7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1437453:BN2145 RS28070
gene id: 1437453:BN2145_RS28070
uniprot id: A0A0F7VY60
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437453:BN2145 RS07300
gene id: 1437453:BN2145_RS07300
uniprot id: A0A0F7VMR4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS23905
gene id: 1437453:BN2145_RS23905
uniprot id: A0A0F7VW27
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1437453:BN2145 RS17555
gene id: 1437453:BN2145_RS17555
uniprot id: A0A0F7VQG8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1437453:BN2145 RS12785
gene id: 1437453:BN2145_RS12785
uniprot id: A0A0F7VPG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1437453:BN2145 RS14220
gene id: 1437453:BN2145_RS14220
uniprot id: A0A0F7VWV2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS26615
gene id: 1437453:BN2145_RS26615
uniprot id: A0A0F7W0Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1437453:BN2145 RS25785
gene id: 1437453:BN2145_RS25785
uniprot id: A0A0F7W332
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1437453:BN2145 RS07655
gene id: 1437453:BN2145_RS07655
uniprot id: A0A0F7VUT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

1437453:BN2145 RS29785
gene id: 1437453:BN2145_RS29785
uniprot id: A0A0F7W6Z3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1437453:BN2145 RS09170
gene id: 1437453:BN2145_RS09170
uniprot id: A0A0F7VU42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1437453:BN2145 RS25620
gene id: 1437453:BN2145_RS25620
uniprot id: A0A0F7VUK9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1437453:BN2145 RS23405
gene id: 1437453:BN2145_RS23405
uniprot id: A0A0F7VZ14
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS16375
gene id: 1437453:BN2145_RS16375
uniprot id: A0A0F7VY67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1437453:BN2145 RS23050
gene id: 1437453:BN2145_RS23050
uniprot id: A0A0F7VTC4
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1437453:BN2145 RS11785
gene id: 1437453:BN2145_RS11785
uniprot id: A0A0F7VP31
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1437453:BN2145 RS29810
gene id: 1437453:BN2145_RS29810
uniprot id: A0A0F7VZ63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1437453:BN2145 RS10635
gene id: 1437453:BN2145_RS10635
uniprot id: A0A0F7VNS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1437453:BN2145 RS16185
gene id: 1437453:BN2145_RS16185
uniprot id: A0A0F7VQ05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1437453:BN2145 RS16295
gene id: 1437453:BN2145_RS16295
uniprot id: A0A0F7VY29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1437453:BN2145 RS32370
gene id: 1437453:BN2145_RS32370
uniprot id: A0A0F7VYL5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS31670
gene id: 1437453:BN2145_RS31670
uniprot id: A0A0F7W851
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1437453:BN2145 RS01915
gene id: 1437453:BN2145_RS01915
uniprot id: A0A0F7VN02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1437453:BN2145 RS23015
gene id: 1437453:BN2145_RS23015
uniprot id: A0A0F7W1M9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1437453:BN2145 RS24440
gene id: 1437453:BN2145_RS24440
uniprot id: A0A0F7VU33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1437453:BN2145 RS21580
gene id: 1437453:BN2145_RS21580
uniprot id: A0A0F7W0Y9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS28160
gene id: 1437453:BN2145_RS28160
uniprot id: A0A0F7W1M6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1437453:BN2145 RS18975
gene id: 1437453:BN2145_RS18975
uniprot id: A0A0F7VR53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1437453:BN2145 RS05625
gene id: 1437453:BN2145_RS05625
uniprot id: A0A0F7VTU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1437453:BN2145 RS27945
gene id: 1437453:BN2145_RS27945
uniprot id: A0A0F7VW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1437453:BN2145 RS33555
gene id: 1437453:BN2145_RS33555
uniprot id: A0A0F7VZ49
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1437453:BN2145 RS32810
gene id: 1437453:BN2145_RS32810
uniprot id: A0A0F7W8U1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1437453:BN2145 RS13020
gene id: 1437453:BN2145_RS13020
uniprot id: A0A0F7VNR8
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1437453:BN2145 RS16345
gene id: 1437453:BN2145_RS16345
uniprot id: A0A0F7W0D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1437453:BN2145 RS14000
gene id: 1437453:BN2145_RS14000
uniprot id: A0A0F7VQ81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1437453:BN2145 RS00135
gene id: 1437453:BN2145_RS00135
uniprot id: A0A0F7VKZ3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1437453:BN2145 RS16095
gene id: 1437453:BN2145_RS16095
uniprot id: A0A0F7W0B1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1437453:BN2145 RS32695
gene id: 1437453:BN2145_RS32695
uniprot id: A0A0F7W4H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1437453:BN2145 RS04775
gene id: 1437453:BN2145_RS04775
uniprot id: A0A0F7VL76
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1437453:BN2145 RS16525
gene id: 1437453:BN2145_RS16525
uniprot id: A0A0F7VQ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1437453:BN2145 RS22590
gene id: 1437453:BN2145_RS22590
uniprot id: A0A0F7VYJ3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS11615
gene id: 1437453:BN2145_RS11615
uniprot id: A0A0F7VVF1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1437453:BN2145 RS07120
gene id: 1437453:BN2145_RS07120
uniprot id: A0A0F7VLS5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS19055
gene id: 1437453:BN2145_RS19055
uniprot id: A0A0F7W1X1
names: Similarity
messages: Belongs to the LOR family.

1437453:BN2145 RS08450
gene id: 1437453:BN2145_RS08450
uniprot id: A0A0F7VTM7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Homotetramer.

1437453:BN2145 RS03485
gene id: 1437453:BN2145_RS03485
uniprot id: A0A0F7VKZ1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1437453:BN2145 RS16990
gene id: 1437453:BN2145_RS16990
uniprot id: A0A0F7VVU1
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS28730
gene id: 1437453:BN2145_RS28730
uniprot id: A0A0F7VWG0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS25050
gene id: 1437453:BN2145_RS25050
uniprot id: A0A0F7VWJ6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1437453:BN2145 RS08470
gene id: 1437453:BN2145_RS08470
uniprot id: A0A0F7VVA8
names: Similarity
messages: Belongs to the malate synthase family.

1437453:BN2145 RS22185
gene id: 1437453:BN2145_RS22185
uniprot id: A0A0F7VYE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1437453:BN2145 RS24695
gene id: 1437453:BN2145_RS24695
uniprot id: A0A0F7VU75
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1437453:BN2145 RS16140
gene id: 1437453:BN2145_RS16140
uniprot id: A0A0F7W0B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1437453:BN2145 RS09540
gene id: 1437453:BN2145_RS09540
uniprot id: A0A0F7VUC6
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS01815
gene id: 1437453:BN2145_RS01815
uniprot id: A0A0F7VQ70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1437453:BN2145 RS16265
gene id: 1437453:BN2145_RS16265
uniprot id: A0A0F7VRL5
names: Similarity
messages: Belongs to the peptidase S1 family.

1437453:BN2145 RS02705
gene id: 1437453:BN2145_RS02705
uniprot id: A0A0F7VLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1437453:BN2145 RS32305
gene id: 1437453:BN2145_RS32305
uniprot id: A0A0F7W6R8
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS17305
gene id: 1437453:BN2145_RS17305
uniprot id: A0A0F7VS69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1437453:BN2145 RS23195
gene id: 1437453:BN2145_RS23195
uniprot id: A0A0F7W1R2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1437453:BN2145 RS17125
gene id: 1437453:BN2145_RS17125
uniprot id: A0A0F7VS37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1437453:BN2145 RS16630
gene id: 1437453:BN2145_RS16630
uniprot id: A0A0F7VRU7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS30015
gene id: 1437453:BN2145_RS30015
uniprot id: A0A0F7W738
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1437453:BN2145 RS23770
gene id: 1437453:BN2145_RS23770
uniprot id: A0A0F7VW05
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS19640
gene id: 1437453:BN2145_RS19640
uniprot id: A0A0F7VZW3
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS08000
gene id: 1437453:BN2145_RS08000
uniprot id: A0A0F7VMY3
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1437453:BN2145 RS09445
gene id: 1437453:BN2145_RS09445
uniprot id: A0A0F7VU84
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1437453:BN2145 RS31175
gene id: 1437453:BN2145_RS31175
uniprot id: A0A0F7W6C0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1437453:BN2145 RS15465
gene id: 1437453:BN2145_RS15465
uniprot id: A0A0F7VR39
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS34665
gene id: 1437453:BN2145_RS34665
uniprot id: A0A0F7W218
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1437453:BN2145 RS29885
gene id: 1437453:BN2145_RS29885
uniprot id: A0A0F7VZ74
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1437453:BN2145 RS12140
gene id: 1437453:BN2145_RS12140
uniprot id: A0A0F7VP87
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS01500
gene id: 1437453:BN2145_RS01500
uniprot id: A0A0F7VRR3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS27010
gene id: 1437453:BN2145_RS27010
uniprot id: A0A0F7W5R3
names: Similarity
messages: Belongs to the YggT family.

1437453:BN2145 RS16785
gene id: 1437453:BN2145_RS16785
uniprot id: A0A0F7W0N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS30065
gene id: 1437453:BN2145_RS30065
uniprot id: A0A0F7W5K1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS21520
gene id: 1437453:BN2145_RS21520
uniprot id: A0A0F7VUS8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS07340
gene id: 1437453:BN2145_RS07340
uniprot id: A0A0F7VPZ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS19965
gene id: 1437453:BN2145_RS19965
uniprot id: A0A0F7VTX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

1437453:BN2145 RS18695
gene id: 1437453:BN2145_RS18695
uniprot id: A0A0F7VTD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1437453:BN2145 RS18250
gene id: 1437453:BN2145_RS18250
uniprot id: A0A0F7VT01
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1437453:BN2145 RS10955
gene id: 1437453:BN2145_RS10955
uniprot id: A0A0F7VV38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1437453:BN2145 RS12425
gene id: 1437453:BN2145_RS12425
uniprot id: A0A0F7VSZ1
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1437453:BN2145 RS13675
gene id: 1437453:BN2145_RS13675
uniprot id: A0A0F7VQ26
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1437453:BN2145 RS27750
gene id: 1437453:BN2145_RS27750
uniprot id: A0A0F7VY03
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS28350
gene id: 1437453:BN2145_RS28350
uniprot id: A0A0F7W4J6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1437453:BN2145 RS32035
gene id: 1437453:BN2145_RS32035
uniprot id: A0A0F7W456
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS03865
gene id: 1437453:BN2145_RS03865
uniprot id: A0A0F7VR56
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1437453:BN2145 RS31515
gene id: 1437453:BN2145_RS31515
uniprot id: A0A0F7VY40
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1437453:BN2145 RS12040
gene id: 1437453:BN2145_RS12040
uniprot id: A0A0F7VVP1
names: Cofactor
messages: Binds 1 FAD per subunit.

1437453:BN2145 RS31310
gene id: 1437453:BN2145_RS31310
uniprot id: A0A0F7VY09
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1437453:BN2145 RS02560
gene id: 1437453:BN2145_RS02560
uniprot id: A0A0F7VN74
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS02545
gene id: 1437453:BN2145_RS02545
uniprot id: A0A0F7VKU3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS02925
gene id: 1437453:BN2145_RS02925
uniprot id: A0A0F7VLN9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1437453:BN2145 RS03035
gene id: 1437453:BN2145_RS03035
uniprot id: A0A0F7VSH2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1437453:BN2145 RS12315
gene id: 1437453:BN2145_RS12315
uniprot id: A0A0F7VXP7
names: Similarity
messages: Belongs to the thioesterase family.

1437453:BN2145 RS11740
gene id: 1437453:BN2145_RS11740
uniprot id: A0A0F7VXB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1437453:BN2145 RS30980
gene id: 1437453:BN2145_RS30980
uniprot id: A0A0F7W632
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1437453:BN2145 RS08445
gene id: 1437453:BN2145_RS08445
uniprot id: A0A0F7VVA4
names: Similarity
messages: Belongs to the allantoicase family.

1437453:BN2145 RS23900
gene id: 1437453:BN2145_RS23900
uniprot id: A0A0F7VTQ3
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1437453:BN2145 RS08915
gene id: 1437453:BN2145_RS08915
uniprot id: A0A0F7VQW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1437453:BN2145 RS04245
gene id: 1437453:BN2145_RS04245
uniprot id: A0A0F7VNU9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS27605
gene id: 1437453:BN2145_RS27605
uniprot id: A0A0F7W619
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1437453:BN2145 RS17570
gene id: 1437453:BN2145_RS17570
uniprot id: A0A0F7VYS9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1437453:BN2145 RS12175
gene id: 1437453:BN2145_RS12175
uniprot id: A0A0F7VVR3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1437453:BN2145 RS28205
gene id: 1437453:BN2145_RS28205
uniprot id: A0A0F7W4B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1437453:BN2145 RS26835
gene id: 1437453:BN2145_RS26835
uniprot id: A0A0F7W3L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1437453:BN2145 RS16985
gene id: 1437453:BN2145_RS16985
uniprot id: A0A0F7VYF5
names: Similarity
messages: Belongs to the UbiD family.

1437453:BN2145 RS17385
gene id: 1437453:BN2145_RS17385
uniprot id: A0A0F7W0Z0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS09795
gene id: 1437453:BN2145_RS09795
uniprot id: A0A0F7VNH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS01835
gene id: 1437453:BN2145_RS01835
uniprot id: A0A0F7VRV8
names: Cofactor
messages: Can also use Mn(2+) ion.

1437453:BN2145 RS24540
gene id: 1437453:BN2145_RS24540
uniprot id: A0A0F7VZK1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1437453:BN2145 RS23305
gene id: 1437453:BN2145_RS23305
uniprot id: A0A0F7VYZ5
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1437453:BN2145 RS05010
gene id: 1437453:BN2145_RS05010
uniprot id: A0A0F7VTD6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1437453:BN2145 RS14955
gene id: 1437453:BN2145_RS14955
uniprot id: A0A0F7VPJ9
names: Similarity
messages: Belongs to the DSD1 family.

1437453:BN2145 RS24950
gene id: 1437453:BN2145_RS24950
uniprot id: A0A0F7VWI6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS28865
gene id: 1437453:BN2145_RS28865
uniprot id: A0A0F7W6M4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1437453:BN2145 RS28260
gene id: 1437453:BN2145_RS28260
uniprot id: A0A0F7W1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS06475
gene id: 1437453:BN2145_RS06475
uniprot id: A0A0F7VPN7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS12570
gene id: 1437453:BN2145_RS12570
uniprot id: A0A0F7VVY8
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1437453:BN2145 RS11520
gene id: 1437453:BN2145_RS11520
uniprot id: A0A0F7VSI2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS15720
gene id: 1437453:BN2145_RS15720
uniprot id: A0A0F7VR96
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS27645
gene id: 1437453:BN2145_RS27645
uniprot id: A0A0F7VVX0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1437453:BN2145 RS36945
gene id: 1437453:BN2145_RS36945
uniprot id: A0A0F7VYZ9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS03960
gene id: 1437453:BN2145_RS03960
uniprot id: A0A0F7VSV6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1437453:BN2145 RS17465
gene id: 1437453:BN2145_RS17465
uniprot id: A0A0F7W101
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1437453:BN2145 RS02860
gene id: 1437453:BN2145_RS02860
uniprot id: A0A0F7VND1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS28495
gene id: 1437453:BN2145_RS28495
uniprot id: A0A0F7W216
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1437453:BN2145 RS07445
gene id: 1437453:BN2145_RS07445
uniprot id: A0A0F7VUN9
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1437453:BN2145 RS08615
gene id: 1437453:BN2145_RS08615
uniprot id: A0A0F7VN53
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

1437453:BN2145 RS16125
gene id: 1437453:BN2145_RS16125
uniprot id: A0A0F7VVD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1437453:BN2145 RS10680
gene id: 1437453:BN2145_RS10680
uniprot id: A0A0F7VMY6
names: Similarity
messages: Belongs to the RelA/SpoT family.

1437453:BN2145 RS30830
gene id: 1437453:BN2145_RS30830
uniprot id: A0A0F7W5Y3
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS34110
gene id: 1437453:BN2145_RS34110
uniprot id: A0A0F7W5F2
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1437453:BN2145 RS34085
gene id: 1437453:BN2145_RS34085
uniprot id: A0A0F7W5F0
names: Similarity
messages: Belongs to the asparagine synthetase family.

1437453:BN2145 RS05940
gene id: 1437453:BN2145_RS05940
uniprot id: A0A0F7VMA7
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

1437453:BN2145 RS26475
gene id: 1437453:BN2145_RS26475
uniprot id: A0A0F7VXB9
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1437453:BN2145 RS27370
gene id: 1437453:BN2145_RS27370
uniprot id: A0A0F7W1A7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1437453:BN2145 RS27815
gene id: 1437453:BN2145_RS27815
uniprot id: A0A0F7W1I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1437453:BN2145 RS14990
gene id: 1437453:BN2145_RS14990
uniprot id: A0A0F7VZN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1437453:BN2145 RS33935
gene id: 1437453:BN2145_RS33935
uniprot id: A0A0F7W5D8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS06625
gene id: 1437453:BN2145_RS06625
uniprot id: A0A0F7VSR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1437453:BN2145 RS16770
gene id: 1437453:BN2145_RS16770
uniprot id: A0A0F7VVP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS27215
gene id: 1437453:BN2145_RS27215
uniprot id: A0A0F7W185
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1437453:BN2145 RS02960
gene id: 1437453:BN2145_RS02960
uniprot id: A0A0F7VQQ0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1437453:BN2145 RS04900
gene id: 1437453:BN2145_RS04900
uniprot id: A0A0F7VP30
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS26575
gene id: 1437453:BN2145_RS26575
uniprot id: A0A0F7VXD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1437453:BN2145 RS20580
gene id: 1437453:BN2145_RS20580
uniprot id: A0A0F7VUA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1437453:BN2145 RS12410
gene id: 1437453:BN2145_RS12410
uniprot id: A0A0F7VPC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: cell wall

1437453:BN2145 RS09235
gene id: 1437453:BN2145_RS09235
uniprot id: A0A0F7VNC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS22255
gene id: 1437453:BN2145_RS22255
uniprot id: A0A0F7W1D1
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1437453:BN2145 RS24155
gene id: 1437453:BN2145_RS24155
uniprot id: A0A0F7VW72
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1437453:BN2145 RS19600
gene id: 1437453:BN2145_RS19600
uniprot id: A0A0F7VRH1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS04050
gene id: 1437453:BN2145_RS04050
uniprot id: A0A0F7VL33
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS09515
gene id: 1437453:BN2145_RS09515
uniprot id: A0A0F7VUB3
names: Similarity
messages: Belongs to the CdaR family.

1437453:BN2145 RS12240
gene id: 1437453:BN2145_RS12240
uniprot id: A0A0F7VXN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1437453:BN2145 RS19080
gene id: 1437453:BN2145_RS19080
uniprot id: A0A0F7W1X2
names: Similarity
messages: Belongs to the peptidase S11 family.

1437453:BN2145 RS33865
gene id: 1437453:BN2145_RS33865
uniprot id: A0A0F7VZA9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS00740
gene id: 1437453:BN2145_RS00740
uniprot id: A0A0F7VRD0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS32350
gene id: 1437453:BN2145_RS32350
uniprot id: A0A0F7W0N0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1437453:BN2145 RS29465
gene id: 1437453:BN2145_RS29465
uniprot id: A0A0F7VWS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1437453:BN2145 RS31280
gene id: 1437453:BN2145_RS31280
uniprot id: A0A0F7W3Q5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1437453:BN2145 RS16890
gene id: 1437453:BN2145_RS16890
uniprot id: A0A0F7VVR9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS28415
gene id: 1437453:BN2145_RS28415
uniprot id: A0A0F7W4N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1437453:BN2145 RS02780
gene id: 1437453:BN2145_RS02780
uniprot id: A0A0F7VQM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS12440
gene id: 1437453:BN2145_RS12440
uniprot id: A0A0F7VVW5
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

1437453:BN2145 RS06010
gene id: 1437453:BN2145_RS06010
uniprot id: A0A0F7VLG8
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1437453:BN2145 RS06025
gene id: 1437453:BN2145_RS06025
uniprot id: A0A0F7VSB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Membrane

1437453:BN2145 RS25975
gene id: 1437453:BN2145_RS25975
uniprot id: A0A0F7W3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1437453:BN2145 RS19290
gene id: 1437453:BN2145_RS19290
uniprot id: A0A0F7VX88
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS27270
gene id: 1437453:BN2145_RS27270
uniprot id: A0A0F7VVQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
messages: Belongs to the glycosyl hydrolase 46 family.
messages: Secreted

1437453:BN2145 RS08665
gene id: 1437453:BN2145_RS08665
uniprot id: A0A0F7VN58
names: Similarity
messages: Belongs to the TPP enzyme family.

1437453:BN2145 RS12825
gene id: 1437453:BN2145_RS12825
uniprot id: A0A0F7VT62
names: Similarity
messages: Belongs to the thioesterase family.

1437453:BN2145 RS29835
gene id: 1437453:BN2145_RS29835
uniprot id: A0A0F7VZ67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1437453:BN2145 RS00640
gene id: 1437453:BN2145_RS00640
uniprot id: A0A0F7VMM0
names: Subcellular Location Annotation
messages: Cytoplasm

1437453:BN2145 RS30805
gene id: 1437453:BN2145_RS30805
uniprot id: A0A0F7W5Y2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1437453:BN2145 RS28100
gene id: 1437453:BN2145_RS28100
uniprot id: A0A0F7W688
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

1437453:BN2145 RS22380
gene id: 1437453:BN2145_RS22380
uniprot id: A0A0F7W1E7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1437453:BN2145 RS22775
gene id: 1437453:BN2145_RS22775
uniprot id: A0A0F7VT76
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS12670
gene id: 1437453:BN2145_RS12670
uniprot id: A0A0F7VW12
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS16205
gene id: 1437453:BN2145_RS16205
uniprot id: A0A0F7VVE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1437453:BN2145 RS28370
gene id: 1437453:BN2145_RS28370
uniprot id: A0A0F7W6G8
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1437453:BN2145 RS32225
gene id: 1437453:BN2145_RS32225
uniprot id: A0A0F7VYH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1437453:BN2145 RS06945
gene id: 1437453:BN2145_RS06945
uniprot id: A0A0F7VPS7
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1437453:BN2145 RS04735
gene id: 1437453:BN2145_RS04735
uniprot id: A0A0F7VT82
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

1437453:BN2145 RS16220
gene id: 1437453:BN2145_RS16220
uniprot id: A0A0F7W0C0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1437453:BN2145 RS15735
gene id: 1437453:BN2145_RS15735
uniprot id: A0A0F7VV61
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1437453:BN2145 RS33495
gene id: 1437453:BN2145_RS33495
uniprot id: A0A0F7W557
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS11855
gene id: 1437453:BN2145_RS11855
uniprot id: A0A0F7VNB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1437453:BN2145 RS02835
gene id: 1437453:BN2145_RS02835
uniprot id: A0A0F7VNC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1437453:BN2145 RS02900
gene id: 1437453:BN2145_RS02900
uniprot id: A0A0F7VLN7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS29985
gene id: 1437453:BN2145_RS29985
uniprot id: A0A0F7VZ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1437453:BN2145 RS07110
gene id: 1437453:BN2145_RS07110
uniprot id: A0A0F7VT02
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1437453:BN2145 RS05610
gene id: 1437453:BN2145_RS05610
uniprot id: A0A0F7VPC8
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS24910
gene id: 1437453:BN2145_RS24910
uniprot id: A0A0F7W505
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1437453:BN2145 RS09985
gene id: 1437453:BN2145_RS09985
uniprot id: A0A0F7VMM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1437453:BN2145 RS14050
gene id: 1437453:BN2145_RS14050
uniprot id: A0A0F7VQ90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1437453:BN2145 RS15700
gene id: 1437453:BN2145_RS15700
uniprot id: A0A0F7W071
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1437453:BN2145 RS22385
gene id: 1437453:BN2145_RS22385
uniprot id: A0A0F7VYH5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS16720
gene id: 1437453:BN2145_RS16720
uniprot id: A0A0F7VVN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS06385
gene id: 1437453:BN2145_RS06385
uniprot id: A0A0F7VME9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS23225
gene id: 1437453:BN2145_RS23225
uniprot id: A0A0F7VYW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS23815
gene id: 1437453:BN2145_RS23815
uniprot id: A0A0F7VZ66
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1437453:BN2145 RS04045
gene id: 1437453:BN2145_RS04045
uniprot id: A0A0F7VNS3
names: Similarity
messages: Belongs to the terpene synthase family.

1437453:BN2145 RS24845
gene id: 1437453:BN2145_RS24845
uniprot id: A0A0F7VZS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1437453:BN2145 RS06660
gene id: 1437453:BN2145_RS06660
uniprot id: A0A0F7VMH4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1437453:BN2145 RS19595
gene id: 1437453:BN2145_RS19595
uniprot id: A0A0F7VXD6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1437453:BN2145 RS25485
gene id: 1437453:BN2145_RS25485
uniprot id: A0A0F7W047
names: Similarity
messages: Belongs to the peptidase S8 family.

1437453:BN2145 RS17785
gene id: 1437453:BN2145_RS17785
uniprot id: A0A0F7VYW2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS32750
gene id: 1437453:BN2145_RS32750
uniprot id: A0A0F7VYT8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1437453:BN2145 RS09800
gene id: 1437453:BN2145_RS09800
uniprot id: A0A0F7VW31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS26975
gene id: 1437453:BN2145_RS26975
uniprot id: A0A0F7VXJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS15350
gene id: 1437453:BN2145_RS15350
uniprot id: A0A0F7VXF4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS30310
gene id: 1437453:BN2145_RS30310
uniprot id: A0A0F7W5M5
names: Similarity
messages: Belongs to the UPF0749 family.

1437453:BN2145 RS20945
gene id: 1437453:BN2145_RS20945
uniprot id: A0A0F7VSC5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS03780
gene id: 1437453:BN2145_RS03780
uniprot id: A0A0F7VL11
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1437453:BN2145 RS06425
gene id: 1437453:BN2145_RS06425
uniprot id: A0A0F7VPN1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1437453:BN2145 RS29840
gene id: 1437453:BN2145_RS29840
uniprot id: A0A0F7W703
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1437453:BN2145 RS27685
gene id: 1437453:BN2145_RS27685
uniprot id: A0A0F7W417
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1437453:BN2145 RS07945
gene id: 1437453:BN2145_RS07945
uniprot id: A0A0F7VM01
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS16155
gene id: 1437453:BN2145_RS16155
uniprot id: A0A0F7VQ02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1437453:BN2145 RS08640
gene id: 1437453:BN2145_RS08640
uniprot id: A0A0F7VN56
names: Similarity
messages: Belongs to the hyi family.

1437453:BN2145 RS17850
gene id: 1437453:BN2145_RS17850
uniprot id: A0A0F7VSG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

1437453:BN2145 RS26325
gene id: 1437453:BN2145_RS26325
uniprot id: A0A0F7VX68
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1437453:BN2145 RS26260
gene id: 1437453:BN2145_RS26260
uniprot id: A0A0F7W0R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1437453:BN2145 RS33615
gene id: 1437453:BN2145_RS33615
uniprot id: A0A0F7W986
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS27535
gene id: 1437453:BN2145_RS27535
uniprot id: A0A0F7W3Z3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1437453:BN2145 RS25105
gene id: 1437453:BN2145_RS25105
uniprot id: A0A0F7W516
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1437453:BN2145 RS32290
gene id: 1437453:BN2145_RS32290
uniprot id: A0A0F7VYK6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1437453:BN2145 RS20235
gene id: 1437453:BN2145_RS20235
uniprot id: A0A0F7VXM5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1437453:BN2145 RS34420
gene id: 1437453:BN2145_RS34420
uniprot id: A0A0F7W9L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1437453:BN2145 RS06100
gene id: 1437453:BN2145_RS06100
uniprot id: A0A0F7VPJ1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1437453:BN2145 RS26640
gene id: 1437453:BN2145_RS26640
uniprot id: A0A0F7W0Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1437453:BN2145 RS30315
gene id: 1437453:BN2145_RS30315
uniprot id: A0A0F7W335
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1437453:BN2145 RS34610
gene id: 1437453:BN2145_RS34610
uniprot id: A0A0F7VZN6
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS14860
gene id: 1437453:BN2145_RS14860
uniprot id: A0A0F7VQL4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS33830
gene id: 1437453:BN2145_RS33830
uniprot id: A0A0F7W7P9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1437453:BN2145 RS08755
gene id: 1437453:BN2145_RS08755
uniprot id: A0A0F7VQV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

1437453:BN2145 RS17810
gene id: 1437453:BN2145_RS17810
uniprot id: A0A0F7VYW7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS14915
gene id: 1437453:BN2145_RS14915
uniprot id: A0A0F7VZM4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS12770
gene id: 1437453:BN2145_RS12770
uniprot id: A0A0F7VW34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1437453:BN2145 RS31145
gene id: 1437453:BN2145_RS31145
uniprot id: A0A0F7W045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1437453:BN2145 RS28555
gene id: 1437453:BN2145_RS28555
uniprot id: A0A0F7VYL6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1437453:BN2145 RS22180
gene id: 1437453:BN2145_RS22180
uniprot id: A0A0F7W1C0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS27590
gene id: 1437453:BN2145_RS27590
uniprot id: A0A0F7W1E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1437453:BN2145 RS10650
gene id: 1437453:BN2145_RS10650
uniprot id: A0A0F7VS27
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1437453:BN2145 RS16120
gene id: 1437453:BN2145_RS16120
uniprot id: A0A0F7W0B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1437453:BN2145 RS25110
gene id: 1437453:BN2145_RS25110
uniprot id: A0A0F7W2S4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS15370
gene id: 1437453:BN2145_RS15370
uniprot id: A0A0F7VZV1
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1437453:BN2145 RS16335
gene id: 1437453:BN2145_RS16335
uniprot id: A0A0F7VRP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1437453:BN2145 RS25440
gene id: 1437453:BN2145_RS25440
uniprot id: A0A0F7VUH2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS04290
gene id: 1437453:BN2145_RS04290
uniprot id: A0A0F7VRB9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS34940
gene id: 1437453:BN2145_RS34940
uniprot id: A0A0F7W9U5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS02180
gene id: 1437453:BN2145_RS02180
uniprot id: A0A0F7VS06
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS12190
gene id: 1437453:BN2145_RS12190
uniprot id: A0A0F7VP94
names: Similarity
messages: Belongs to the LOG family.

1437453:BN2145 RS08265
gene id: 1437453:BN2145_RS08265
uniprot id: A0A0F7VV73
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1437453:BN2145 RS09835
gene id: 1437453:BN2145_RS09835
uniprot id: A0A0F7VRF1
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1437453:BN2145 RS11805
gene id: 1437453:BN2145_RS11805
uniprot id: A0A0F7VNA9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1437453:BN2145 RS06910
gene id: 1437453:BN2145_RS06910
uniprot id: A0A0F7VUE4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1437453:BN2145 RS23385
gene id: 1437453:BN2145_RS23385
uniprot id: A0A0F7VTI6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1437453:BN2145 RS01595
gene id: 1437453:BN2145_RS01595
uniprot id: A0A0F7VQ52
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS21985
gene id: 1437453:BN2145_RS21985
uniprot id: A0A0F7W386
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1437453:BN2145 RS30100
gene id: 1437453:BN2145_RS30100
uniprot id: A0A0F7VX96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1437453:BN2145 RS28735
gene id: 1437453:BN2145_RS28735
uniprot id: A0A0F7VYQ2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS02410
gene id: 1437453:BN2145_RS02410
uniprot id: A0A0F7VS19
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS16210
gene id: 1437453:BN2145_RS16210
uniprot id: A0A0F7VQ09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1437453:BN2145 RS09660
gene id: 1437453:BN2145_RS09660
uniprot id: A0A0F7VUG3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS26435
gene id: 1437453:BN2145_RS26435
uniprot id: A0A0F7W3H3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS33345
gene id: 1437453:BN2145_RS33345
uniprot id: A0A0F7VZ22
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

1437453:BN2145 RS13960
gene id: 1437453:BN2145_RS13960
uniprot id: A0A0F7VWP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1437453:BN2145 RS28970
gene id: 1437453:BN2145_RS28970
uniprot id: A0A0F7W6P1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1437453:BN2145 RS15330
gene id: 1437453:BN2145_RS15330
uniprot id: A0A0F7VUU5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS10350
gene id: 1437453:BN2145_RS10350
uniprot id: A0A0F7VUU7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1437453:BN2145 RS23985
gene id: 1437453:BN2145_RS23985
uniprot id: A0A0F7W4J2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1437453:BN2145 RS25025
gene id: 1437453:BN2145_RS25025
uniprot id: A0A0F7VWJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1437453:BN2145 RS22935
gene id: 1437453:BN2145_RS22935
uniprot id: A0A0F7W3Z6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS26970
gene id: 1437453:BN2145_RS26970
uniprot id: A0A0F7VVJ7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS22830
gene id: 1437453:BN2145_RS22830
uniprot id: A0A0F7VT84
names: Similarity
messages: Belongs to the PGI/PMI family.

1437453:BN2145 RS09790
gene id: 1437453:BN2145_RS09790
uniprot id: A0A0F7VMK7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1437453:BN2145 RS02665
gene id: 1437453:BN2145_RS02665
uniprot id: A0A0F7VKU8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1437453:BN2145 RS09160
gene id: 1437453:BN2145_RS09160
uniprot id: A0A0F7VNB2
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1437453:BN2145 RS09620
gene id: 1437453:BN2145_RS09620
uniprot id: A0A0F7VMJ2
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1437453:BN2145 RS15945
gene id: 1437453:BN2145_RS15945
uniprot id: A0A0F7VRF6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1437453:BN2145 RS33645
gene id: 1437453:BN2145_RS33645
uniprot id: A0A0F7W7L3
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS16790
gene id: 1437453:BN2145_RS16790
uniprot id: A0A0F7VYD2
names: Similarity
messages: Belongs to the peptidase C40 family.

1437453:BN2145 RS03335
gene id: 1437453:BN2145_RS03335
uniprot id: A0A0F7VKY1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1437453:BN2145 RS12365
gene id: 1437453:BN2145_RS12365
uniprot id: A0A0F7VXQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS27805
gene id: 1437453:BN2145_RS27805
uniprot id: A0A0F7W653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS02970
gene id: 1437453:BN2145_RS02970
uniprot id: A0A0F7VKW0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS17585
gene id: 1437453:BN2145_RS17585
uniprot id: A0A0F7VSB0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1437453:BN2145 RS22855
gene id: 1437453:BN2145_RS22855
uniprot id: A0A0F7VT87
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS18315
gene id: 1437453:BN2145_RS18315
uniprot id: A0A0F7VWS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1437453:BN2145 RS09410
gene id: 1437453:BN2145_RS09410
uniprot id: A0A0F7VNF0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS14475
gene id: 1437453:BN2145_RS14475
uniprot id: A0A0F7VUC4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1437453:BN2145 RS17460
gene id: 1437453:BN2145_RS17460
uniprot id: A0A0F7VS90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS11460
gene id: 1437453:BN2145_RS11460
uniprot id: A0A0F7VX43
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1437453:BN2145 RS30570
gene id: 1437453:BN2145_RS30570
uniprot id: A0A0F7W377
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1437453:BN2145 RS29360
gene id: 1437453:BN2145_RS29360
uniprot id: A0A0F7W2N4
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1437453:BN2145 RS15890
gene id: 1437453:BN2145_RS15890
uniprot id: A0A0F7VPV8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1437453:BN2145 RS31170
gene id: 1437453:BN2145_RS31170
uniprot id: A0A0F7W7U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1437453:BN2145 RS35305
gene id: 1437453:BN2145_RS35305
uniprot id: A0A0F7W2B1
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS15925
gene id: 1437453:BN2145_RS15925
uniprot id: A0A0F7W096
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1437453:BN2145 RS00200
gene id: 1437453:BN2145_RS00200
uniprot id: A0A0F7VPB0
names: Similarity
messages: Belongs to the ParB family.

1437453:BN2145 RS16145
gene id: 1437453:BN2145_RS16145
uniprot id: A0A0F7VY04
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1437453:BN2145 RS15660
gene id: 1437453:BN2145_RS15660
uniprot id: A0A0F7VPT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS16100
gene id: 1437453:BN2145_RS16100
uniprot id: A0A0F7VXZ5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1437453:BN2145 RS15340
gene id: 1437453:BN2145_RS15340
uniprot id: A0A0F7VR19
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1437453:BN2145 RS19515
gene id: 1437453:BN2145_RS19515
uniprot id: A0A0F7VZU0
names: Similarity
messages: Belongs to the thioredoxin family.

1437453:BN2145 RS26240
gene id: 1437453:BN2145_RS26240
uniprot id: A0A0F7VV07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS08970
gene id: 1437453:BN2145_RS08970
uniprot id: A0A0F7VMC0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS22840
gene id: 1437453:BN2145_RS22840
uniprot id: A0A0F7W3X8
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS20815
gene id: 1437453:BN2145_RS20815
uniprot id: A0A0F7VXW0
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1437453:BN2145 RS25015
gene id: 1437453:BN2145_RS25015
uniprot id: A0A0F7VZW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1437453:BN2145 RS14315
gene id: 1437453:BN2145_RS14315
uniprot id: A0A0F7VZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS27920
gene id: 1437453:BN2145_RS27920
uniprot id: A0A0F7VW18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS33520
gene id: 1437453:BN2145_RS33520
uniprot id: A0A0F7W7H2
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1437453:BN2145 RS27625
gene id: 1437453:BN2145_RS27625
uniprot id: A0A0F7VXY1
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1437453:BN2145 RS15320
gene id: 1437453:BN2145_RS15320
uniprot id: A0A0F7VZU2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1437453:BN2145 RS04135
gene id: 1437453:BN2145_RS04135
uniprot id: A0A0F7VSY4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1437453:BN2145 RS22735
gene id: 1437453:BN2145_RS22735
uniprot id: A0A0F7W3V5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1437453:BN2145 RS32735
gene id: 1437453:BN2145_RS32735
uniprot id: A0A0F7W8S9
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1437453:BN2145 RS07835
gene id: 1437453:BN2145_RS07835
uniprot id: A0A0F7VTB6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS34555
gene id: 1437453:BN2145_RS34555
uniprot id: A0A0F7W5Q9
names: Similarity
messages: Belongs to the catalase family.

1437453:BN2145 RS15990
gene id: 1437453:BN2145_RS15990
uniprot id: A0A0F7VPW8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1437453:BN2145 RS33825
gene id: 1437453:BN2145_RS33825
uniprot id: A0A0F7W9D8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1437453:BN2145 RS07775
gene id: 1437453:BN2145_RS07775
uniprot id: A0A0F7VMV2
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1437453:BN2145 RS27785
gene id: 1437453:BN2145_RS27785
uniprot id: A0A0F7W435
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1437453:BN2145 RS25940
gene id: 1437453:BN2145_RS25940
uniprot id: A0A0F7VX22
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS31765
gene id: 1437453:BN2145_RS31765
uniprot id: A0A0F7W877
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1437453:BN2145 RS15475
gene id: 1437453:BN2145_RS15475
uniprot id: A0A0F7VXI0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS21600
gene id: 1437453:BN2145_RS21600
uniprot id: A0A0F7W347
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

1437453:BN2145 RS27205
gene id: 1437453:BN2145_RS27205
uniprot id: A0A0F7W5S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1437453:BN2145 RS26345
gene id: 1437453:BN2145_RS26345
uniprot id: A0A0F7VV20
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1437453:BN2145 RS31055
gene id: 1437453:BN2145_RS31055
uniprot id: A0A0F7W3N2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1437453:BN2145 RS05775
gene id: 1437453:BN2145_RS05775
uniprot id: A0A0F7VM90
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1437453:BN2145 RS16160
gene id: 1437453:BN2145_RS16160
uniprot id: A0A0F7VRJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1437453:BN2145 RS31235
gene id: 1437453:BN2145_RS31235
uniprot id: A0A0F7VXZ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS12160
gene id: 1437453:BN2145_RS12160
uniprot id: A0A0F7VNE2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1437453:BN2145 RS19135
gene id: 1437453:BN2145_RS19135
uniprot id: A0A0F7VZM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS30525
gene id: 1437453:BN2145_RS30525
uniprot id: A0A0F7VZM0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1437453:BN2145 RS32990
gene id: 1437453:BN2145_RS32990
uniprot id: A0A0F7W716
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS22040
gene id: 1437453:BN2145_RS22040
uniprot id: A0A0F7VST0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1437453:BN2145 RS27585
gene id: 1437453:BN2145_RS27585
uniprot id: A0A0F7W401
names: Similarity
messages: Belongs to the peptidase S66 family.

1437453:BN2145 RS17670
gene id: 1437453:BN2145_RS17670
uniprot id: A0A0F7W129
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1437453:BN2145 RS19245
gene id: 1437453:BN2145_RS19245
uniprot id: A0A0F7VR86
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1437453:BN2145 RS28530
gene id: 1437453:BN2145_RS28530
uniprot id: A0A0F7VYL4
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1437453:BN2145 RS27315
gene id: 1437453:BN2145_RS27315
uniprot id: A0A0F7W199
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1437453:BN2145 RS12680
gene id: 1437453:BN2145_RS12680
uniprot id: A0A0F7VNJ6
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS12295
gene id: 1437453:BN2145_RS12295
uniprot id: A0A0F7VVT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS10165
gene id: 1437453:BN2145_RS10165
uniprot id: A0A0F7VWB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1437453:BN2145 RS20380
gene id: 1437453:BN2145_RS20380
uniprot id: A0A0F7W2I1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS10275
gene id: 1437453:BN2145_RS10275
uniprot id: A0A0F7VRN1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437453:BN2145 RS10210
gene id: 1437453:BN2145_RS10210
uniprot id: A0A0F7VNL7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS14340
gene id: 1437453:BN2145_RS14340
uniprot id: A0A0F7VZD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1437453:BN2145 RS06065
gene id: 1437453:BN2145_RS06065
uniprot id: A0A0F7VMB6
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1437453:BN2145 RS11545
gene id: 1437453:BN2145_RS11545
uniprot id: A0A0F7VSI5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1437453:BN2145 RS12890
gene id: 1437453:BN2145_RS12890
uniprot id: A0A0F7VY34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1437453:BN2145 RS31230
gene id: 1437453:BN2145_RS31230
uniprot id: A0A0F7W3Q1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS27720
gene id: 1437453:BN2145_RS27720
uniprot id: A0A0F7VVY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1437453:BN2145 RS17750
gene id: 1437453:BN2145_RS17750
uniprot id: A0A0F7VSC1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1437453:BN2145 RS05225
gene id: 1437453:BN2145_RS05225
uniprot id: A0A0F7VRW5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

1437453:BN2145 RS28275
gene id: 1437453:BN2145_RS28275
uniprot id: A0A0F7W6B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1437453:BN2145 RS11685
gene id: 1437453:BN2145_RS11685
uniprot id: A0A0F7VP24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1437453:BN2145 RS25735
gene id: 1437453:BN2145_RS25735
uniprot id: A0A0F7W323
names: Similarity
messages: Belongs to the CdaR family.

1437453:BN2145 RS17635
gene id: 1437453:BN2145_RS17635
uniprot id: A0A0F7VQH5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1437453:BN2145 RS19530
gene id: 1437453:BN2145_RS19530
uniprot id: A0A0F7VTQ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS29575
gene id: 1437453:BN2145_RS29575
uniprot id: A0A0F7VZ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1437453:BN2145 RS13850
gene id: 1437453:BN2145_RS13850
uniprot id: A0A0F7VQ62
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1437453:BN2145 RS10035
gene id: 1437453:BN2145_RS10035
uniprot id: A0A0F7VMM6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS06620
gene id: 1437453:BN2145_RS06620
uniprot id: A0A0F7VU74
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS21670
gene id: 1437453:BN2145_RS21670
uniprot id: A0A0F7VSK5
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

1437453:BN2145 RS15765
gene id: 1437453:BN2145_RS15765
uniprot id: A0A0F7VPU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1437453:BN2145 RS26310
gene id: 1437453:BN2145_RS26310
uniprot id: A0A0F7W3G3
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1437453:BN2145 RS10565
gene id: 1437453:BN2145_RS10565
uniprot id: A0A0F7VWP5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1437453:BN2145 RS14035
gene id: 1437453:BN2145_RS14035
uniprot id: A0A0F7VWQ7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1437453:BN2145 RS16245
gene id: 1437453:BN2145_RS16245
uniprot id: A0A0F7W0C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1437453:BN2145 RS10790
gene id: 1437453:BN2145_RS10790
uniprot id: A0A0F7VWT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS12005
gene id: 1437453:BN2145_RS12005
uniprot id: A0A0F7VND0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1437453:BN2145 RS29730
gene id: 1437453:BN2145_RS29730
uniprot id: A0A0F7VZ35
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1437453:BN2145 RS30835
gene id: 1437453:BN2145_RS30835
uniprot id: A0A0F7W3C0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS33325
gene id: 1437453:BN2145_RS33325
uniprot id: A0A0F7W1B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS25560
gene id: 1437453:BN2145_RS25560
uniprot id: A0A0F7W063
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS15740
gene id: 1437453:BN2145_RS15740
uniprot id: A0A0F7VPU0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1437453:BN2145 RS11635
gene id: 1437453:BN2145_RS11635
uniprot id: A0A0F7VP20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1437453:BN2145 RS26485
gene id: 1437453:BN2145_RS26485
uniprot id: A0A0F7W3H6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1437453:BN2145 RS04205
gene id: 1437453:BN2145_RS04205
uniprot id: A0A0F7VL39
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS01780
gene id: 1437453:BN2145_RS01780
uniprot id: A0A0F7VLG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1437453:BN2145 RS14795
gene id: 1437453:BN2145_RS14795
uniprot id: A0A0F7VX54
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1437453:BN2145 RS23610
gene id: 1437453:BN2145_RS23610
uniprot id: A0A0F7W4F5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS17685
gene id: 1437453:BN2145_RS17685
uniprot id: A0A0F7VQI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1437453:BN2145 RS29705
gene id: 1437453:BN2145_RS29705
uniprot id: A0A0F7W6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1437453:BN2145 RS15970
gene id: 1437453:BN2145_RS15970
uniprot id: A0A0F7VRF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1437453:BN2145 RS08070
gene id: 1437453:BN2145_RS08070
uniprot id: A0A0F7VQK8
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1437453:BN2145 RS12475
gene id: 1437453:BN2145_RS12475
uniprot id: A0A0F7VNH5
names: Subcellular Location Annotation
messages: Cytoplasm

1437453:BN2145 RS17100
gene id: 1437453:BN2145_RS17100
uniprot id: A0A0F7VS33
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1437453:BN2145 RS01305
gene id: 1437453:BN2145_RS01305
uniprot id: A0A0F7VLC1
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS24675
gene id: 1437453:BN2145_RS24675
uniprot id: A0A0F7VWB5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1437453:BN2145 RS09975
gene id: 1437453:BN2145_RS09975
uniprot id: A0A0F7VUL7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS30650
gene id: 1437453:BN2145_RS30650
uniprot id: A0A0F7VZS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS06675
gene id: 1437453:BN2145_RS06675
uniprot id: A0A0F7VPP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS18270
gene id: 1437453:BN2145_RS18270
uniprot id: A0A0F7VQS6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1437453:BN2145 RS34185
gene id: 1437453:BN2145_RS34185
uniprot id: A0A0F7W5F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1437453:BN2145 RS28985
gene id: 1437453:BN2145_RS28985
uniprot id: A0A0F7VWI2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS23190
gene id: 1437453:BN2145_RS23190
uniprot id: A0A0F7W441
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1437453:BN2145 RS14420
gene id: 1437453:BN2145_RS14420
uniprot id: A0A0F7VWX9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1437453:BN2145 RS23725
gene id: 1437453:BN2145_RS23725
uniprot id: A0A0F7W253
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1437453:BN2145 RS31745
gene id: 1437453:BN2145_RS31745
uniprot id: A0A0F7W6H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

1437453:BN2145 RS29790
gene id: 1437453:BN2145_RS29790
uniprot id: A0A0F7W5B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1437453:BN2145 RS03550
gene id: 1437453:BN2145_RS03550
uniprot id: A0A0F7VQZ6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1437453:BN2145 RS25910
gene id: 1437453:BN2145_RS25910
uniprot id: A0A0F7VUY0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS16045
gene id: 1437453:BN2145_RS16045
uniprot id: A0A0F7W0A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1437453:BN2145 RS22700
gene id: 1437453:BN2145_RS22700
uniprot id: A0A0F7VVG4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1437453:BN2145 RS20780
gene id: 1437453:BN2145_RS20780
uniprot id: A0A0F7W2T8
names: Similarity
messages: Belongs to the peptidase C40 family.

1437453:BN2145 RS12265
gene id: 1437453:BN2145_RS12265
uniprot id: A0A0F7VXP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS28610
gene id: 1437453:BN2145_RS28610
uniprot id: A0A0F7VYM3
names: Similarity
messages: Belongs to the peptidase S1 family.

1437453:BN2145 RS07845
gene id: 1437453:BN2145_RS07845
uniprot id: A0A0F7VLY1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1437453:BN2145 RS20400
gene id: 1437453:BN2145_RS20400
uniprot id: A0A0F7VU64
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS22390
gene id: 1437453:BN2145_RS22390
uniprot id: A0A0F7VSY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1437453:BN2145 RS11405
gene id: 1437453:BN2145_RS11405
uniprot id: A0A0F7VNZ3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1437453:BN2145 RS28855
gene id: 1437453:BN2145_RS28855
uniprot id: A0A0F7VWH2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS28880
gene id: 1437453:BN2145_RS28880
uniprot id: A0A0F7VWH4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS25080
gene id: 1437453:BN2145_RS25080
uniprot id: A0A0F7W515
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1437453:BN2145 RS09055
gene id: 1437453:BN2145_RS09055
uniprot id: A0A0F7VMD4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1437453:BN2145 RS06190
gene id: 1437453:BN2145_RS06190
uniprot id: A0A0F7VLI7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS30900
gene id: 1437453:BN2145_RS30900
uniprot id: A0A0F7W7K1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS16500
gene id: 1437453:BN2145_RS16500
uniprot id: A0A0F7VVJ6
names: Similarity
messages: Belongs to the UPF0234 family.

1437453:BN2145 RS04200
gene id: 1437453:BN2145_RS04200
uniprot id: A0A0F7VNU3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1437453:BN2145 RS29405
gene id: 1437453:BN2145_RS29405
uniprot id: A0A0F7W534
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1437453:BN2145 RS01785
gene id: 1437453:BN2145_RS01785
uniprot id: A0A0F7VRV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS34180
gene id: 1437453:BN2145_RS34180
uniprot id: A0A0F7W7V6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS33165
gene id: 1437453:BN2145_RS33165
uniprot id: A0A0F7W4T0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS12530
gene id: 1437453:BN2145_RS12530
uniprot id: A0A0F7VPE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1437453:BN2145 RS10510
gene id: 1437453:BN2145_RS10510
uniprot id: A0A0F7VNQ9
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1437453:BN2145 RS34200
gene id: 1437453:BN2145_RS34200
uniprot id: A0A0F7W9J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1437453:BN2145 RS11820
gene id: 1437453:BN2145_RS11820
uniprot id: A0A0F7VVJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1437453:BN2145 RS30605
gene id: 1437453:BN2145_RS30605
uniprot id: A0A0F7VZQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS27000
gene id: 1437453:BN2145_RS27000
uniprot id: A0A0F7VVK2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1437453:BN2145 RS17515
gene id: 1437453:BN2145_RS17515
uniprot id: A0A0F7W111
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS34800
gene id: 1437453:BN2145_RS34800
uniprot id: A0A0F7W838
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS26315
gene id: 1437453:BN2145_RS26315
uniprot id: A0A0F7W0S8
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS03460
gene id: 1437453:BN2145_RS03460
uniprot id: A0A0F7VKY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UbiX/PAD1 family. YclB subfamily.
messages: Homododecamer.
messages: Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase.

1437453:BN2145 RS26650
gene id: 1437453:BN2145_RS26650
uniprot id: A0A0F7VXF2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS20255
gene id: 1437453:BN2145_RS20255
uniprot id: A0A0F7W042
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1437453:BN2145 RS02870
gene id: 1437453:BN2145_RS02870
uniprot id: A0A0F7VKV6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS09015
gene id: 1437453:BN2145_RS09015
uniprot id: A0A0F7VVK0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1437453:BN2145 RS29950
gene id: 1437453:BN2145_RS29950
uniprot id: A0A0F7W2X8
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

1437453:BN2145 RS30945
gene id: 1437453:BN2145_RS30945
uniprot id: A0A0F7W006
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS12470
gene id: 1437453:BN2145_RS12470
uniprot id: A0A0F7VSZ9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS22140
gene id: 1437453:BN2145_RS22140
uniprot id: A0A0F7VSU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1437453:BN2145 RS21945
gene id: 1437453:BN2145_RS21945
uniprot id: A0A0F7W153
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS10435
gene id: 1437453:BN2145_RS10435
uniprot id: A0A0F7VWM7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1437453:BN2145 RS12780
gene id: 1437453:BN2145_RS12780
uniprot id: A0A0F7VNK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1437453:BN2145 RS04630
gene id: 1437453:BN2145_RS04630
uniprot id: A0A0F7VM09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1437453:BN2145 RS16005
gene id: 1437453:BN2145_RS16005
uniprot id: A0A0F7VXX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1437453:BN2145 RS23895
gene id: 1437453:BN2145_RS23895
uniprot id: A0A0F7VZ94
names: Similarity
messages: Belongs to the IucA/IucC family.

1437453:BN2145 RS08055
gene id: 1437453:BN2145_RS08055
uniprot id: A0A0F7VMZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1437453:BN2145 RS26215
gene id: 1437453:BN2145_RS26215
uniprot id: A0A0F7VV05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1437453:BN2145 RS31950
gene id: 1437453:BN2145_RS31950
uniprot id: A0A0F7W8A5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1437453:BN2145 RS11220
gene id: 1437453:BN2145_RS11220
uniprot id: A0A0F7VSF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1437453:BN2145 RS05195
gene id: 1437453:BN2145_RS05195
uniprot id: A0A0F7VTH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS29965
gene id: 1437453:BN2145_RS29965
uniprot id: A0A0F7W728
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1437453:BN2145 RS34425
gene id: 1437453:BN2145_RS34425
uniprot id: A0A0F7W7Z0
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

1437453:BN2145 RS13550
gene id: 1437453:BN2145_RS13550
uniprot id: A0A0F7VNY1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1437453:BN2145 RS14045
gene id: 1437453:BN2145_RS14045
uniprot id: A0A0F7VP70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1437453:BN2145 RS17660
gene id: 1437453:BN2145_RS17660
uniprot id: A0A0F7VQH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1437453:BN2145 RS05785
gene id: 1437453:BN2145_RS05785
uniprot id: A0A0F7VS91
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1437453:BN2145 RS18810
gene id: 1437453:BN2145_RS18810
uniprot id: A0A0F7W1V9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS12715
gene id: 1437453:BN2145_RS12715
uniprot id: A0A0F7VXX2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1437453:BN2145 RS18470
gene id: 1437453:BN2145_RS18470
uniprot id: A0A0F7VQX9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1437453:BN2145 RS06520
gene id: 1437453:BN2145_RS06520
uniprot id: A0A0F7VU57
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1437453:BN2145 RS28805
gene id: 1437453:BN2145_RS28805
uniprot id: A0A0F7VWG8
names: Similarity
messages: Belongs to the peptidase S45 family.

1437453:BN2145 RS09020
gene id: 1437453:BN2145_RS09020
uniprot id: A0A0F7VTX6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1437453:BN2145 RS15935
gene id: 1437453:BN2145_RS15935
uniprot id: A0A0F7VV99
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS27200
gene id: 1437453:BN2145_RS27200
uniprot id: A0A0F7VXM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1437453:BN2145 RS04080
gene id: 1437453:BN2145_RS04080
uniprot id: A0A0F7VLY3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS14405
gene id: 1437453:BN2145_RS14405
uniprot id: A0A0F7VPB8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1437453:BN2145 RS20260
gene id: 1437453:BN2145_RS20260
uniprot id: A0A0F7VXM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1437453:BN2145 RS18370
gene id: 1437453:BN2145_RS18370
uniprot id: A0A0F7VQU2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS34295
gene id: 1437453:BN2145_RS34295
uniprot id: A0A0F7W1V5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS26245
gene id: 1437453:BN2145_RS26245
uniprot id: A0A0F7VX57
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1437453:BN2145 RS19005
gene id: 1437453:BN2145_RS19005
uniprot id: A0A0F7VTG6
names: Similarity
messages: Belongs to the pirin family.

1437453:BN2145 RS20270
gene id: 1437453:BN2145_RS20270
uniprot id: A0A0F7VU43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS22770
gene id: 1437453:BN2145_RS22770
uniprot id: A0A0F7VYM8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monovalent cation. The ion could be potassium.

1437453:BN2145 RS14685
gene id: 1437453:BN2145_RS14685
uniprot id: A0A0F7VZI2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS27105
gene id: 1437453:BN2145_RS27105
uniprot id: A0A0F7W5R7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1437453:BN2145 RS34145
gene id: 1437453:BN2145_RS34145
uniprot id: A0A0F7W1S8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS24060
gene id: 1437453:BN2145_RS24060
uniprot id: A0A0F7W4K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1437453:BN2145 RS23295
gene id: 1437453:BN2145_RS23295
uniprot id: A0A0F7W498
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS06905
gene id: 1437453:BN2145_RS06905
uniprot id: A0A0F7VMK1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1437453:BN2145 RS15210
gene id: 1437453:BN2145_RS15210
uniprot id: A0A0F7VPL5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1437453:BN2145 RS11375
gene id: 1437453:BN2145_RS11375
uniprot id: A0A0F7VN60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1437453:BN2145 RS07520
gene id: 1437453:BN2145_RS07520
uniprot id: A0A0F7VUQ7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS34965
gene id: 1437453:BN2145_RS34965
uniprot id: A0A0F7W9U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1437453:BN2145 RS12300
gene id: 1437453:BN2145_RS12300
uniprot id: A0A0F7VSW9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1437453:BN2145 RS11550
gene id: 1437453:BN2145_RS11550
uniprot id: A0A0F7VN87
names: Similarity
messages: Belongs to the DprA/Smf family.

1437453:BN2145 RS25045
gene id: 1437453:BN2145_RS25045
uniprot id: A0A0F7VUC3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1437453:BN2145 RS16850
gene id: 1437453:BN2145_RS16850
uniprot id: A0A0F7VQ97
names: Similarity
messages: Belongs to the peptidase A24 family.

1437453:BN2145 RS23360
gene id: 1437453:BN2145_RS23360
uniprot id: A0A0F7VTI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1437453:BN2145 RS31880
gene id: 1437453:BN2145_RS31880
uniprot id: A0A0F7VYA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1437453:BN2145 RS26960
gene id: 1437453:BN2145_RS26960
uniprot id: A0A0F7W3R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS10810
gene id: 1437453:BN2145_RS10810
uniprot id: A0A0F7VNT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1437453:BN2145 RS04850
gene id: 1437453:BN2145_RS04850
uniprot id: A0A0F7VL82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS31115
gene id: 1437453:BN2145_RS31115
uniprot id: A0A0F7VXU3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1437453:BN2145 RS19915
gene id: 1437453:BN2145_RS19915
uniprot id: A0A0F7W004
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS22445
gene id: 1437453:BN2145_RS22445
uniprot id: A0A0F7VT24
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1437453:BN2145 RS28280
gene id: 1437453:BN2145_RS28280
uniprot id: A0A0F7W4D7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1437453:BN2145 RS07725
gene id: 1437453:BN2145_RS07725
uniprot id: A0A0F7VMU6
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS25090
gene id: 1437453:BN2145_RS25090
uniprot id: A0A0F7VZX5
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

1437453:BN2145 RS03880
gene id: 1437453:BN2145_RS03880
uniprot id: A0A0F7VLW5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1437453:BN2145 RS11800
gene id: 1437453:BN2145_RS11800
uniprot id: A0A0F7VSN0
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1437453:BN2145 RS23840
gene id: 1437453:BN2145_RS23840
uniprot id: A0A0F7VZ69
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1437453:BN2145 RS10670
gene id: 1437453:BN2145_RS10670
uniprot id: A0A0F7VV02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1437453:BN2145 RS06280
gene id: 1437453:BN2145_RS06280
uniprot id: A0A0F7VSJ8
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1437453:BN2145 RS07620
gene id: 1437453:BN2145_RS07620
uniprot id: A0A0F7VLW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

1437453:BN2145 RS15760
gene id: 1437453:BN2145_RS15760
uniprot id: A0A0F7VV65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1437453:BN2145 RS09415
gene id: 1437453:BN2145_RS09415
uniprot id: A0A0F7VVS4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1437453:BN2145 RS29690
gene id: 1437453:BN2145_RS29690
uniprot id: A0A0F7W2T4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1437453:BN2145 RS32040
gene id: 1437453:BN2145_RS32040
uniprot id: A0A0F7VYC5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS17175
gene id: 1437453:BN2145_RS17175
uniprot id: A0A0F7W0V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1437453:BN2145 RS18195
gene id: 1437453:BN2145_RS18195
uniprot id: A0A0F7VWQ4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS15225
gene id: 1437453:BN2145_RS15225
uniprot id: A0A0F7VXC6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1437453:BN2145 RS17355
gene id: 1437453:BN2145_RS17355
uniprot id: A0A0F7VS78
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

1437453:BN2145 RS07865
gene id: 1437453:BN2145_RS07865
uniprot id: A0A0F7VQB3
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS16835
gene id: 1437453:BN2145_RS16835
uniprot id: A0A0F7W0P3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1437453:BN2145 RS11590
gene id: 1437453:BN2145_RS11590
uniprot id: A0A0F7VVE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1437453:BN2145 RS19520
gene id: 1437453:BN2145_RS19520
uniprot id: A0A0F7VXC2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1437453:BN2145 RS31320
gene id: 1437453:BN2145_RS31320
uniprot id: A0A0F7W7X3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS25700
gene id: 1437453:BN2145_RS25700
uniprot id: A0A0F7VWW4
names: Similarity
messages: Belongs to the aldose epimerase family.

1437453:BN2145 RS15965
gene id: 1437453:BN2145_RS15965
uniprot id: A0A0F7VPW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1437453:BN2145 RS20540
gene id: 1437453:BN2145_RS20540
uniprot id: A0A0F7VRY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1437453:BN2145 RS13600
gene id: 1437453:BN2145_RS13600
uniprot id: A0A0F7VQ16
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS20525
gene id: 1437453:BN2145_RS20525
uniprot id: A0A0F7W2L4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS10990
gene id: 1437453:BN2145_RS10990
uniprot id: A0A0F7VN18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1437453:BN2145 RS16730
gene id: 1437453:BN2145_RS16730
uniprot id: A0A0F7VRX0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS18480
gene id: 1437453:BN2145_RS18480
uniprot id: A0A0F7W1R8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1437453:BN2145 RS29225
gene id: 1437453:BN2145_RS29225
uniprot id: A0A0F7W6S8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1437453:BN2145 RS31415
gene id: 1437453:BN2145_RS31415
uniprot id: A0A0F7W0B7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS19015
gene id: 1437453:BN2145_RS19015
uniprot id: A0A0F7VZK5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS30175
gene id: 1437453:BN2145_RS30175
uniprot id: A0A0F7VXA9
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1437453:BN2145 RS23065
gene id: 1437453:BN2145_RS23065
uniprot id: A0A0F7W1N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS29075
gene id: 1437453:BN2145_RS29075
uniprot id: A0A0F7W6Q6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1437453:BN2145 RS00730
gene id: 1437453:BN2145_RS00730
uniprot id: A0A0F7VKL8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS12010
gene id: 1437453:BN2145_RS12010
uniprot id: A0A0F7VP51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits.
messages: In the C-terminal section; belongs to the urease beta subunit family.
messages: In the N-terminal section; belongs to the urease gamma subunit family.

1437453:BN2145 RS12875
gene id: 1437453:BN2145_RS12875
uniprot id: A0A0F7VT66
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1437453:BN2145 RS29295
gene id: 1437453:BN2145_RS29295
uniprot id: A0A0F7VYX3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1437453:BN2145 RS06765
gene id: 1437453:BN2145_RS06765
uniprot id: A0A0F7VSU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1437453:BN2145 RS02885
gene id: 1437453:BN2145_RS02885
uniprot id: A0A0F7VQN5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS29420
gene id: 1437453:BN2145_RS29420
uniprot id: A0A0F7VZ05
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS14500
gene id: 1437453:BN2145_RS14500
uniprot id: A0A0F7VUC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS30170
gene id: 1437453:BN2145_RS30170
uniprot id: A0A0F7W313
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1437453:BN2145 RS03725
gene id: 1437453:BN2145_RS03725
uniprot id: A0A0F7VNP9
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS28320
gene id: 1437453:BN2145_RS28320
uniprot id: A0A0F7W6C2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1437453:BN2145 RS04285
gene id: 1437453:BN2145_RS04285
uniprot id: A0A0F7VT07
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS08060
gene id: 1437453:BN2145_RS08060
uniprot id: A0A0F7VV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1437453:BN2145 RS15520
gene id: 1437453:BN2145_RS15520
uniprot id: A0A0F7VR44
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1437453:BN2145 RS20930
gene id: 1437453:BN2145_RS20930
uniprot id: A0A0F7W2W1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS29385
gene id: 1437453:BN2145_RS29385
uniprot id: A0A0F7W2N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1437453:BN2145 RS30820
gene id: 1437453:BN2145_RS30820
uniprot id: A0A0F7VZW0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1437453:BN2145 RS32770
gene id: 1437453:BN2145_RS32770
uniprot id: A0A0F7W4K3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS25725
gene id: 1437453:BN2145_RS25725
uniprot id: A0A0F7VWW7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1437453:BN2145 RS22250
gene id: 1437453:BN2145_RS22250
uniprot id: A0A0F7W3E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1437453:BN2145 RS30355
gene id: 1437453:BN2145_RS30355
uniprot id: A0A0F7W7B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1437453:BN2145 RS14615
gene id: 1437453:BN2145_RS14615
uniprot id: A0A0F7VX00
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437453:BN2145 RS02490
gene id: 1437453:BN2145_RS02490
uniprot id: A0A0F7VN68
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1437453:BN2145 RS16370
gene id: 1437453:BN2145_RS16370
uniprot id: A0A0F7W0D6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1437453:BN2145 RS04990
gene id: 1437453:BN2145_RS04990
uniprot id: A0A0F7VRQ5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS23115
gene id: 1437453:BN2145_RS23115
uniprot id: A0A0F7W1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1437453:BN2145 RS12790
gene id: 1437453:BN2145_RS12790
uniprot id: A0A0F7VXY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1437453:BN2145 RS20810
gene id: 1437453:BN2145_RS20810
uniprot id: A0A0F7W0J5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS23170
gene id: 1437453:BN2145_RS23170
uniprot id: A0A0F7W1Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1437453:BN2145 RS01535
gene id: 1437453:BN2145_RS01535
uniprot id: A0A0F7VMW5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1437453:BN2145 RS08800
gene id: 1437453:BN2145_RS08800
uniprot id: A0A0F7VVH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1437453:BN2145 RS11185
gene id: 1437453:BN2145_RS11185
uniprot id: A0A0F7VV74
names: Similarity
messages: Belongs to the ribF family.

1437453:BN2145 RS12210
gene id: 1437453:BN2145_RS12210
uniprot id: A0A0F7VNE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS25630
gene id: 1437453:BN2145_RS25630
uniprot id: A0A0F7W575
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

1437453:BN2145 RS28310
gene id: 1437453:BN2145_RS28310
uniprot id: A0A0F7VW89
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1437453:BN2145 RS17015
gene id: 1437453:BN2145_RS17015
uniprot id: A0A0F7VVU5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS28950
gene id: 1437453:BN2145_RS28950
uniprot id: A0A0F7W4W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1437453:BN2145 RS30320
gene id: 1437453:BN2145_RS30320
uniprot id: A0A0F7VXD7
names: Similarity
messages: Belongs to the UPF0749 family.

1437453:BN2145 RS28590
gene id: 1437453:BN2145_RS28590
uniprot id: A0A0F7W6J1
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS21575
gene id: 1437453:BN2145_RS21575
uniprot id: A0A0F7W346
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS23705
gene id: 1437453:BN2145_RS23705
uniprot id: A0A0F7VZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS15960
gene id: 1437453:BN2145_RS15960
uniprot id: A0A0F7VVA2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437453:BN2145 RS25570
gene id: 1437453:BN2145_RS25570
uniprot id: A0A0F7VWU8
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1437453:BN2145 RS34475
gene id: 1437453:BN2145_RS34475
uniprot id: A0A0F7W7Z4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1437453:BN2145 RS14705
gene id: 1437453:BN2145_RS14705
uniprot id: A0A0F7VQJ4
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1437453:BN2145 RS17680
gene id: 1437453:BN2145_RS17680
uniprot id: A0A0F7VW73
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1437453:BN2145 RS07095
gene id: 1437453:BN2145_RS07095
uniprot id: A0A0F7VLS2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS08905
gene id: 1437453:BN2145_RS08905
uniprot id: A0A0F7VVI6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1437453:BN2145 RS32710
gene id: 1437453:BN2145_RS32710
uniprot id: A0A0F7W8S4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1437453:BN2145 RS27030
gene id: 1437453:BN2145_RS27030
uniprot id: A0A0F7VXK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1437453:BN2145 RS08550
gene id: 1437453:BN2145_RS08550
uniprot id: A0A0F7VTP0
names: Similarity
messages: Belongs to the IucA/IucC family.

1437453:BN2145 RS10105
gene id: 1437453:BN2145_RS10105
uniprot id: A0A0F7VMN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1437453:BN2145 RS10595
gene id: 1437453:BN2145_RS10595
uniprot id: A0A0F7VUZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1437453:BN2145 RS19265
gene id: 1437453:BN2145_RS19265
uniprot id: A0A0F7VX85
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS19560
gene id: 1437453:BN2145_RS19560
uniprot id: A0A0F7W244
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1437453:BN2145 RS18430
gene id: 1437453:BN2145_RS18430
uniprot id: A0A0F7W1R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1437453:BN2145 RS23980
gene id: 1437453:BN2145_RS23980
uniprot id: A0A0F7VW37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1437453:BN2145 RS31285
gene id: 1437453:BN2145_RS31285
uniprot id: A0A0F7VY05
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

1437453:BN2145 RS10155
gene id: 1437453:BN2145_RS10155
uniprot id: A0A0F7VMP0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1437453:BN2145 RS07030
gene id: 1437453:BN2145_RS07030
uniprot id: A0A0F7VUF4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1437453:BN2145 RS25060
gene id: 1437453:BN2145_RS25060
uniprot id: A0A0F7W2R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1437453:BN2145 RS16350
gene id: 1437453:BN2145_RS16350
uniprot id: A0A0F7VY62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1437453:BN2145 RS33690
gene id: 1437453:BN2145_RS33690
uniprot id: A0A0F7W9C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS03360
gene id: 1437453:BN2145_RS03360
uniprot id: A0A0F7VKY3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1437453:BN2145 RS07220
gene id: 1437453:BN2145_RS07220
uniprot id: A0A0F7VPY3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

1437453:BN2145 RS16860
gene id: 1437453:BN2145_RS16860
uniprot id: A0A0F7VYE2
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1437453:BN2145 RS25385
gene id: 1437453:BN2145_RS25385
uniprot id: A0A0F7VUG1
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS28410
gene id: 1437453:BN2145_RS28410
uniprot id: A0A0F7W6H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1437453:BN2145 RS07420
gene id: 1437453:BN2145_RS07420
uniprot id: A0A0F7VMS0
names: Similarity
messages: Belongs to the peptidase S8 family.

1437453:BN2145 RS17610
gene id: 1437453:BN2145_RS17610
uniprot id: A0A0F7VSB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

1437453:BN2145 RS29365
gene id: 1437453:BN2145_RS29365
uniprot id: A0A0F7VWQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1437453:BN2145 RS12510
gene id: 1437453:BN2145_RS12510
uniprot id: A0A0F7VXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS11670
gene id: 1437453:BN2145_RS11670
uniprot id: A0A0F7VVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1437453:BN2145 RS14815
gene id: 1437453:BN2145_RS14815
uniprot id: A0A0F7VZK8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS03510
gene id: 1437453:BN2145_RS03510
uniprot id: A0A0F7VKZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS29860
gene id: 1437453:BN2145_RS29860
uniprot id: A0A0F7VZ70
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS16190
gene id: 1437453:BN2145_RS16190
uniprot id: A0A0F7VRK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1437453:BN2145 RS14590
gene id: 1437453:BN2145_RS14590
uniprot id: A0A0F7VWZ5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1437453:BN2145 RS11170
gene id: 1437453:BN2145_RS11170
uniprot id: A0A0F7VN36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS24505
gene id: 1437453:BN2145_RS24505
uniprot id: A0A0F7W4S5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS27905
gene id: 1437453:BN2145_RS27905
uniprot id: A0A0F7W662
names: Similarity
messages: Belongs to the DapA family.

1437453:BN2145 RS16075
gene id: 1437453:BN2145_RS16075
uniprot id: A0A0F7VXZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1437453:BN2145 RS06715
gene id: 1437453:BN2145_RS06715
uniprot id: A0A0F7VU86
names: Similarity
messages: Belongs to the peptidase M1 family.

1437453:BN2145 RS10695
gene id: 1437453:BN2145_RS10695
uniprot id: A0A0F7VV04
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1437453:BN2145 RS33675
gene id: 1437453:BN2145_RS33675
uniprot id: A0A0F7W599
names: Similarity
messages: Belongs to the pirin family.

1437453:BN2145 RS06560
gene id: 1437453:BN2145_RS06560
uniprot id: A0A0F7VLM6
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

1437453:BN2145 RS24170
gene id: 1437453:BN2145_RS24170
uniprot id: A0A0F7VZE0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS34970
gene id: 1437453:BN2145_RS34970
uniprot id: A0A0F7W878
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1437453:BN2145 RS32630
gene id: 1437453:BN2145_RS32630
uniprot id: A0A0F7W0W4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1437453:BN2145 RS14715
gene id: 1437453:BN2145_RS14715
uniprot id: A0A0F7VX41
names: Similarity
messages: Belongs to the FBPase class 2 family.

1437453:BN2145 RS22135
gene id: 1437453:BN2145_RS22135
uniprot id: A0A0F7W1B3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437453:BN2145 RS22220
gene id: 1437453:BN2145_RS22220
uniprot id: A0A0F7VV90
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1437453:BN2145 RS30965
gene id: 1437453:BN2145_RS30965
uniprot id: A0A0F7VXS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1437453:BN2145 RS06200
gene id: 1437453:BN2145_RS06200
uniprot id: A0A0F7VU11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1437453:BN2145 RS08235
gene id: 1437453:BN2145_RS08235
uniprot id: A0A0F7VN11
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS11775
gene id: 1437453:BN2145_RS11775
uniprot id: A0A0F7VSM6
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1437453:BN2145 RS26980
gene id: 1437453:BN2145_RS26980
uniprot id: A0A0F7W5R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

1437453:BN2145 RS17470
gene id: 1437453:BN2145_RS17470
uniprot id: A0A0F7VYP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

1437453:BN2145 RS16200
gene id: 1437453:BN2145_RS16200
uniprot id: A0A0F7VY11
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1437453:BN2145 RS12760
gene id: 1437453:BN2145_RS12760
uniprot id: A0A0F7VPG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1437453:BN2145 RS23490
gene id: 1437453:BN2145_RS23490
uniprot id: A0A0F7VTK0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS14610
gene id: 1437453:BN2145_RS14610
uniprot id: A0A0F7VZH5
names: Similarity
messages: Belongs to the peptidase S8 family.

1437453:BN2145 RS18390
gene id: 1437453:BN2145_RS18390
uniprot id: A0A0F7VWV3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS20350
gene id: 1437453:BN2145_RS20350
uniprot id: A0A0F7W2H7
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1437453:BN2145 RS10420
gene id: 1437453:BN2145_RS10420
uniprot id: A0A0F7VRT6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1437453:BN2145 RS23950
gene id: 1437453:BN2145_RS23950
uniprot id: A0A0F7VTQ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS31985
gene id: 1437453:BN2145_RS31985
uniprot id: A0A0F7W447
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1437453:BN2145 RS22835
gene id: 1437453:BN2145_RS22835
uniprot id: A0A0F7VVI3
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1437453:BN2145 RS29355
gene id: 1437453:BN2145_RS29355
uniprot id: A0A0F7W527
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1437453:BN2145 RS10235
gene id: 1437453:BN2145_RS10235
uniprot id: A0A0F7VNM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1437453:BN2145 RS29275
gene id: 1437453:BN2145_RS29275
uniprot id: A0A0F7W6T0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1437453:BN2145 RS32940
gene id: 1437453:BN2145_RS32940
uniprot id: A0A0F7W705
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1437453:BN2145 RS32070
gene id: 1437453:BN2145_RS32070
uniprot id: A0A0F7W0I0
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1437453:BN2145 RS25295
gene id: 1437453:BN2145_RS25295
uniprot id: A0A0F7W005
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1437453:BN2145 RS28830
gene id: 1437453:BN2145_RS28830
uniprot id: A0A0F7VWH0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS20170
gene id: 1437453:BN2145_RS20170
uniprot id: A0A0F7W032
names: Similarity
messages: Belongs to the GARS family.

1437453:BN2145 RS29750
gene id: 1437453:BN2145_RS29750
uniprot id: A0A0F7VWX1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS19145
gene id: 1437453:BN2145_RS19145
uniprot id: A0A0F7VR68
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1437453:BN2145 RS29185
gene id: 1437453:BN2145_RS29185
uniprot id: A0A0F7W2K5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1437453:BN2145 RS19320
gene id: 1437453:BN2145_RS19320
uniprot id: A0A0F7VTN4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS19020
gene id: 1437453:BN2145_RS19020
uniprot id: A0A0F7VX47
names: Similarity
messages: Belongs to the peptidase M18 family.

1437453:BN2145 RS04940
gene id: 1437453:BN2145_RS04940
uniprot id: A0A0F7VTC5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1437453:BN2145 RS14885
gene id: 1437453:BN2145_RS14885
uniprot id: A0A0F7VQL9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS12285
gene id: 1437453:BN2145_RS12285
uniprot id: A0A0F7VPA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1437453:BN2145 RS10780
gene id: 1437453:BN2145_RS10780
uniprot id: A0A0F7VMZ8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1437453:BN2145 RS05250
gene id: 1437453:BN2145_RS05250
uniprot id: A0A0F7VRW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1437453:BN2145 RS28980
gene id: 1437453:BN2145_RS28980
uniprot id: A0A0F7W2G6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1437453:BN2145 RS30985
gene id: 1437453:BN2145_RS30985
uniprot id: A0A0F7W3M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1437453:BN2145 RS21040
gene id: 1437453:BN2145_RS21040
uniprot id: A0A0F7W0M7
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1437453:BN2145 RS04930
gene id: 1437453:BN2145_RS04930
uniprot id: A0A0F7VL87
names: Similarity
messages: Belongs to the FPG family.

1437453:BN2145 RS23625
gene id: 1437453:BN2145_RS23625
uniprot id: A0A0F7VTM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1437453:BN2145 RS32060
gene id: 1437453:BN2145_RS32060
uniprot id: A0A0F7W459
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1437453:BN2145 RS29930
gene id: 1437453:BN2145_RS29930
uniprot id: A0A0F7VX70
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1437453:BN2145 RS23925
gene id: 1437453:BN2145_RS23925
uniprot id: A0A0F7VTQ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS10225
gene id: 1437453:BN2145_RS10225
uniprot id: A0A0F7VRM3
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS22950
gene id: 1437453:BN2145_RS22950
uniprot id: A0A0F7VT97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1437453:BN2145 RS32120
gene id: 1437453:BN2145_RS32120
uniprot id: A0A0F7W468
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

1437453:BN2145 RS04770
gene id: 1437453:BN2145_RS04770
uniprot id: A0A0F7VP19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1437453:BN2145 RS34450
gene id: 1437453:BN2145_RS34450
uniprot id: A0A0F7W7Z2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1437453:BN2145 RS22125
gene id: 1437453:BN2145_RS22125
uniprot id: A0A0F7VV32
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1437453:BN2145 RS26270
gene id: 1437453:BN2145_RS26270
uniprot id: A0A0F7VX61
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS00260
gene id: 1437453:BN2145_RS00260
uniprot id: A0A0F7VQY8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS11610
gene id: 1437453:BN2145_RS11610
uniprot id: A0A0F7VX69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1437453:BN2145 RS29460
gene id: 1437453:BN2145_RS29460
uniprot id: A0A0F7W2Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS15060
gene id: 1437453:BN2145_RS15060
uniprot id: A0A0F7VQR9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1437453:BN2145 RS11125
gene id: 1437453:BN2145_RS11125
uniprot id: A0A0F7VNW8
names: Similarity
messages: Belongs to the WXG100 family.

1437453:BN2145 RS27725
gene id: 1437453:BN2145_RS27725
uniprot id: A0A0F7VXZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1437453:BN2145 RS08860
gene id: 1437453:BN2145_RS08860
uniprot id: A0A0F7VTV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1437453:BN2145 RS06210
gene id: 1437453:BN2145_RS06210
uniprot id: A0A0F7VPL2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1437453:BN2145 RS10630
gene id: 1437453:BN2145_RS10630
uniprot id: A0A0F7VMY2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1437453:BN2145 RS28125
gene id: 1437453:BN2145_RS28125
uniprot id: A0A0F7W692
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1437453:BN2145 RS09110
gene id: 1437453:BN2145_RS09110
uniprot id: A0A0F7VNA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1437453:BN2145 RS05835
gene id: 1437453:BN2145_RS05835
uniprot id: A0A0F7VPF0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1437453:BN2145 RS09690
gene id: 1437453:BN2145_RS09690
uniprot id: A0A0F7VRD4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1437453:BN2145 RS27985
gene id: 1437453:BN2145_RS27985
uniprot id: A0A0F7W472
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS28020
gene id: 1437453:BN2145_RS28020
uniprot id: A0A0F7VY52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1437453:BN2145 RS22260
gene id: 1437453:BN2145_RS22260
uniprot id: A0A0F7VYF3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1437453:BN2145 RS34430
gene id: 1437453:BN2145_RS34430
uniprot id: A0A0F7W5J8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1437453:BN2145 RS22150
gene id: 1437453:BN2145_RS22150
uniprot id: A0A0F7W3D6
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS25065
gene id: 1437453:BN2145_RS25065
uniprot id: A0A0F7VZX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1437453:BN2145 RS07820
gene id: 1437453:BN2145_RS07820
uniprot id: A0A0F7VLX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1437453:BN2145 RS31260
gene id: 1437453:BN2145_RS31260
uniprot id: A0A0F7VY01
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS21090
gene id: 1437453:BN2145_RS21090
uniprot id: A0A0F7W0R0
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1437453:BN2145 RS28255
gene id: 1437453:BN2145_RS28255
uniprot id: A0A0F7W4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1437453:BN2145 RS16545
gene id: 1437453:BN2145_RS16545
uniprot id: A0A0F7VVK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS08375
gene id: 1437453:BN2145_RS08375
uniprot id: A0A0F7VTK7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1437453:BN2145 RS05260
gene id: 1437453:BN2145_RS05260
uniprot id: A0A0F7VLA8
names: Similarity
messages: Belongs to the CobH/CbiC family.

1437453:BN2145 RS21755
gene id: 1437453:BN2145_RS21755
uniprot id: A0A0F7W361
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1437453:BN2145 RS05605
gene id: 1437453:BN2145_RS05605
uniprot id: A0A0F7VS66
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS28360
gene id: 1437453:BN2145_RS28360
uniprot id: A0A0F7VWA4
names: Similarity
messages: Belongs to the UPF0098 family.

1437453:BN2145 RS20690
gene id: 1437453:BN2145_RS20690
uniprot id: A0A0F7VXS0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1437453:BN2145 RS20975
gene id: 1437453:BN2145_RS20975
uniprot id: A0A0F7VUM7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1437453:BN2145 RS18215
gene id: 1437453:BN2145_RS18215
uniprot id: A0A0F7VWR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1437453:BN2145 RS11935
gene id: 1437453:BN2145_RS11935
uniprot id: A0A0F7VP45
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1437453:BN2145 RS16330
gene id: 1437453:BN2145_RS16330
uniprot id: A0A0F7VQ22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1437453:BN2145 RS09265
gene id: 1437453:BN2145_RS09265
uniprot id: A0A0F7VVQ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1437453:BN2145 RS24875
gene id: 1437453:BN2145_RS24875
uniprot id: A0A0F7VU98
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1437453:BN2145 RS17730
gene id: 1437453:BN2145_RS17730
uniprot id: A0A0F7VYV2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS13790
gene id: 1437453:BN2145_RS13790
uniprot id: A0A0F7VWL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS06680
gene id: 1437453:BN2145_RS06680
uniprot id: A0A0F7VLN6
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1437453:BN2145 RS29995
gene id: 1437453:BN2145_RS29995
uniprot id: A0A0F7W5E2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1437453:BN2145 RS05430
gene id: 1437453:BN2145_RS05430
uniprot id: A0A0F7VM70
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1437453:BN2145 RS03065
gene id: 1437453:BN2145_RS03065
uniprot id: A0A0F7VSH4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1437453:BN2145 RS19070
gene id: 1437453:BN2145_RS19070
uniprot id: A0A0F7VR63
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS24535
gene id: 1437453:BN2145_RS24535
uniprot id: A0A0F7W2H5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS12000
gene id: 1437453:BN2145_RS12000
uniprot id: A0A0F7VSR7
names: Similarity
messages: Belongs to the agmatine deiminase family.

1437453:BN2145 RS33370
gene id: 1437453:BN2145_RS33370
uniprot id: A0A0F7W4W0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1437453:BN2145 RS24380
gene id: 1437453:BN2145_RS24380
uniprot id: A0A0F7W2F2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1437453:BN2145 RS24705
gene id: 1437453:BN2145_RS24705
uniprot id: A0A0F7W4X6
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1437453:BN2145 RS23930
gene id: 1437453:BN2145_RS23930
uniprot id: A0A0F7VW30
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1437453:BN2145 RS25565
gene id: 1437453:BN2145_RS25565
uniprot id: A0A0F7VUJ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1437453:BN2145 RS28630
gene id: 1437453:BN2145_RS28630
uniprot id: A0A0F7VWE0
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1437453:BN2145 RS13865
gene id: 1437453:BN2145_RS13865
uniprot id: A0A0F7VU22
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1437453:BN2145 RS34370
gene id: 1437453:BN2145_RS34370
uniprot id: A0A0F7W1X6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS07825
gene id: 1437453:BN2145_RS07825
uniprot id: A0A0F7VMV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1437453:BN2145 RS17215
gene id: 1437453:BN2145_RS17215
uniprot id: A0A0F7VQE1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437453:BN2145 RS02510
gene id: 1437453:BN2145_RS02510
uniprot id: A0A0F7VQI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1437453:BN2145 RS27975
gene id: 1437453:BN2145_RS27975
uniprot id: A0A0F7VY44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

1437453:BN2145 RS16710
gene id: 1437453:BN2145_RS16710
uniprot id: A0A0F7W0J3
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1437453:BN2145 RS05955
gene id: 1437453:BN2145_RS05955
uniprot id: A0A0F7VPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS33620
gene id: 1437453:BN2145_RS33620
uniprot id: A0A0F7W7K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1437453:BN2145 RS15850
gene id: 1437453:BN2145_RS15850
uniprot id: A0A0F7W090
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS34560
gene id: 1437453:BN2145_RS34560
uniprot id: A0A0F7VZN0
names: Similarity
messages: Belongs to the fructosamine kinase family.

1437453:BN2145 RS26395
gene id: 1437453:BN2145_RS26395
uniprot id: A0A0F7VV30
names: Similarity
messages: Belongs to the ArsC family.

1437453:BN2145 RS04835
gene id: 1437453:BN2145_RS04835
uniprot id: A0A0F7VTB7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1437453:BN2145 RS03975
gene id: 1437453:BN2145_RS03975
uniprot id: A0A0F7VL30
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

1437453:BN2145 RS30300
gene id: 1437453:BN2145_RS30300
uniprot id: A0A0F7VZD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1437453:BN2145 RS12870
gene id: 1437453:BN2145_RS12870
uniprot id: A0A0F7VW58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1437453:BN2145 RS14525
gene id: 1437453:BN2145_RS14525
uniprot id: A0A0F7VUD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS16865
gene id: 1437453:BN2145_RS16865
uniprot id: A0A0F7VVR5
names: Subcellular Location Annotation
messages: Cytoplasm

1437453:BN2145 RS24160
gene id: 1437453:BN2145_RS24160
uniprot id: A0A0F7W4L8
names: Similarity
messages: Belongs to the citrate synthase family.

1437453:BN2145 RS12575
gene id: 1437453:BN2145_RS12575
uniprot id: A0A0F7VT19
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS26105
gene id: 1437453:BN2145_RS26105
uniprot id: A0A0F7VUZ5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1437453:BN2145 RS22755
gene id: 1437453:BN2145_RS22755
uniprot id: A0A0F7VVH1
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1437453:BN2145 RS03920
gene id: 1437453:BN2145_RS03920
uniprot id: A0A0F7VNR2
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS19810
gene id: 1437453:BN2145_RS19810
uniprot id: A0A0F7W279
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1437453:BN2145 RS00830
gene id: 1437453:BN2145_RS00830
uniprot id: A0A0F7VMP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1437453:BN2145 RS34280
gene id: 1437453:BN2145_RS34280
uniprot id: A0A0F7W7X2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1437453:BN2145 RS35260
gene id: 1437453:BN2145_RS35260
uniprot id: A0A0F7W9X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1437453:BN2145 RS35160
gene id: 1437453:BN2145_RS35160
uniprot id: A0A0F7W9W3
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS29255
gene id: 1437453:BN2145_RS29255
uniprot id: A0A0F7W503
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS15825
gene id: 1437453:BN2145_RS15825
uniprot id: A0A0F7W087
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS09765
gene id: 1437453:BN2145_RS09765
uniprot id: A0A0F7VNH2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1437453:BN2145 RS01830
gene id: 1437453:BN2145_RS01830
uniprot id: A0A0F7VLG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1437453:BN2145 RS29155
gene id: 1437453:BN2145_RS29155
uniprot id: A0A0F7W4Y7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1437453:BN2145 RS09405
gene id: 1437453:BN2145_RS09405
uniprot id: A0A0F7VMI1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1437453:BN2145 RS17860
gene id: 1437453:BN2145_RS17860
uniprot id: A0A0F7VYX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1437453:BN2145 RS32220
gene id: 1437453:BN2145_RS32220
uniprot id: A0A0F7W484
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1437453:BN2145 RS08610
gene id: 1437453:BN2145_RS08610
uniprot id: A0A0F7VM67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1437453:BN2145 RS08195
gene id: 1437453:BN2145_RS08195
uniprot id: A0A0F7VTJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS24280
gene id: 1437453:BN2145_RS24280
uniprot id: A0A0F7W2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1437453:BN2145 RS22475
gene id: 1437453:BN2145_RS22475
uniprot id: A0A0F7VVD4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1437453:BN2145 RS13925
gene id: 1437453:BN2145_RS13925
uniprot id: A0A0F7VQ71
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS25255
gene id: 1437453:BN2145_RS25255
uniprot id: A0A0F7VWL9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1437453:BN2145 RS27450
gene id: 1437453:BN2145_RS27450
uniprot id: A0A0F7VXU7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1437453:BN2145 RS09335
gene id: 1437453:BN2145_RS09335
uniprot id: A0A0F7VND2
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.

1437453:BN2145 RS32840
gene id: 1437453:BN2145_RS32840
uniprot id: A0A0F7W6Y5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS15450
gene id: 1437453:BN2145_RS15450
uniprot id: A0A0F7VXH5
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1437453:BN2145 RS32365
gene id: 1437453:BN2145_RS32365
uniprot id: A0A0F7W4B3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1437453:BN2145 RS34915
gene id: 1437453:BN2145_RS34915
uniprot id: A0A0F7W9U4
names: Similarity
messages: Belongs to the TPP enzyme family.

1437453:BN2145 RS27940
gene id: 1437453:BN2145_RS27940
uniprot id: A0A0F7W1K0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1437453:BN2145 RS24880
gene id: 1437453:BN2145_RS24880
uniprot id: A0A0F7VWE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1437453:BN2145 RS08885
gene id: 1437453:BN2145_RS08885
uniprot id: A0A0F7VTV8
names: Similarity
messages: Belongs to the TPP enzyme family.

1437453:BN2145 RS07635
gene id: 1437453:BN2145_RS07635
uniprot id: A0A0F7VT93
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

1437453:BN2145 RS22285
gene id: 1437453:BN2145_RS22285
uniprot id: A0A0F7VYF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

1437453:BN2145 RS29720
gene id: 1437453:BN2145_RS29720
uniprot id: A0A0F7VWU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS24920
gene id: 1437453:BN2145_RS24920
uniprot id: A0A0F7VWG3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1437453:BN2145 RS27885
gene id: 1437453:BN2145_RS27885
uniprot id: A0A0F7W454
names: Similarity
messages: Belongs to the DapA family.

1437453:BN2145 RS26630
gene id: 1437453:BN2145_RS26630
uniprot id: A0A0F7W5M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS27790
gene id: 1437453:BN2145_RS27790
uniprot id: A0A0F7W1H6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1437453:BN2145 RS17545
gene id: 1437453:BN2145_RS17545
uniprot id: A0A0F7VYS3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1437453:BN2145 RS09140
gene id: 1437453:BN2145_RS09140
uniprot id: A0A0F7VVM5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS33205
gene id: 1437453:BN2145_RS33205
uniprot id: A0A0F7W8Z6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1437453:BN2145 RS10340
gene id: 1437453:BN2145_RS10340
uniprot id: A0A0F7VWF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1437453:BN2145 RS11655
gene id: 1437453:BN2145_RS11655
uniprot id: A0A0F7VN95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS26600
gene id: 1437453:BN2145_RS26600
uniprot id: A0A0F7VXE5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1437453:BN2145 RS06590
gene id: 1437453:BN2145_RS06590
uniprot id: A0A0F7VMG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS25480
gene id: 1437453:BN2145_RS25480
uniprot id: A0A0F7W2Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS16195
gene id: 1437453:BN2145_RS16195
uniprot id: A0A0F7W0B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1437453:BN2145 RS19505
gene id: 1437453:BN2145_RS19505
uniprot id: A0A0F7VTQ6
names: Similarity
messages: Belongs to the ParB family.

1437453:BN2145 RS16765
gene id: 1437453:BN2145_RS16765
uniprot id: A0A0F7VYD0
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

1437453:BN2145 RS26300
gene id: 1437453:BN2145_RS26300
uniprot id: A0A0F7VX65
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS11310
gene id: 1437453:BN2145_RS11310
uniprot id: A0A0F7VX01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS23200
gene id: 1437453:BN2145_RS23200
uniprot id: A0A0F7VYW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS34230
gene id: 1437453:BN2145_RS34230
uniprot id: A0A0F7W7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1437453:BN2145 RS29765
gene id: 1437453:BN2145_RS29765
uniprot id: A0A0F7W5A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1437453:BN2145 RS11575
gene id: 1437453:BN2145_RS11575
uniprot id: A0A0F7VN89
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1437453:BN2145 RS06615
gene id: 1437453:BN2145_RS06615
uniprot id: A0A0F7VMH0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1437453:BN2145 RS11245
gene id: 1437453:BN2145_RS11245
uniprot id: A0A0F7VSF4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS13310
gene id: 1437453:BN2145_RS13310
uniprot id: A0A0F7VNV9
names: Similarity
messages: Belongs to the EccE family.

1437453:BN2145 RS24890
gene id: 1437453:BN2145_RS24890
uniprot id: A0A0F7W2N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1437453:BN2145 RS30245
gene id: 1437453:BN2145_RS30245
uniprot id: A0A0F7W324
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1437453:BN2145 RS27345
gene id: 1437453:BN2145_RS27345
uniprot id: A0A0F7W1A3
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS09510
gene id: 1437453:BN2145_RS09510
uniprot id: A0A0F7VVX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS19060
gene id: 1437453:BN2145_RS19060
uniprot id: A0A0F7VZL3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1437453:BN2145 RS19815
gene id: 1437453:BN2145_RS19815
uniprot id: A0A0F7VZZ1
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS28235
gene id: 1437453:BN2145_RS28235
uniprot id: A0A0F7W1P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1437453:BN2145 RS29485
gene id: 1437453:BN2145_RS29485
uniprot id: A0A0F7W2Q4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1437453:BN2145 RS12520
gene id: 1437453:BN2145_RS12520
uniprot id: A0A0F7VT09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS29715
gene id: 1437453:BN2145_RS29715
uniprot id: A0A0F7W2T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1437453:BN2145 RS20410
gene id: 1437453:BN2145_RS20410
uniprot id: A0A0F7W068
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1437453:BN2145 RS27630
gene id: 1437453:BN2145_RS27630
uniprot id: A0A0F7W621
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1437453:BN2145 RS04710
gene id: 1437453:BN2145_RS04710
uniprot id: A0A0F7VT79
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1437453:BN2145 RS07900
gene id: 1437453:BN2145_RS07900
uniprot id: A0A0F7VMX1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1437453:BN2145 RS19735
gene id: 1437453:BN2145_RS19735
uniprot id: A0A0F7W269
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1437453:BN2145 RS23290
gene id: 1437453:BN2145_RS23290
uniprot id: A0A0F7VVT3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1437453:BN2145 RS10870
gene id: 1437453:BN2145_RS10870
uniprot id: A0A0F7VV29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1437453:BN2145 RS26605
gene id: 1437453:BN2145_RS26605
uniprot id: A0A0F7W5M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1437453:BN2145 RS04920
gene id: 1437453:BN2145_RS04920
uniprot id: A0A0F7VRP2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS26610
gene id: 1437453:BN2145_RS26610
uniprot id: A0A0F7W3J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1437453:BN2145 RS25625
gene id: 1437453:BN2145_RS25625
uniprot id: A0A0F7VWV5
names: Similarity
messages: Belongs to the aldose epimerase family.

1437453:BN2145 RS05765
gene id: 1437453:BN2145_RS05765
uniprot id: A0A0F7VPE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS04740
gene id: 1437453:BN2145_RS04740
uniprot id: A0A0F7VRL7
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

1437453:BN2145 RS25205
gene id: 1437453:BN2145_RS25205
uniprot id: A0A0F7VWL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS30915
gene id: 1437453:BN2145_RS30915
uniprot id: A0A0F7VXS1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1437453:BN2145 RS26890
gene id: 1437453:BN2145_RS26890
uniprot id: A0A0F7W132
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS07115
gene id: 1437453:BN2145_RS07115
uniprot id: A0A0F7VPX0
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

1437453:BN2145 RS16550
gene id: 1437453:BN2145_RS16550
uniprot id: A0A0F7VQ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1437453:BN2145 RS20230
gene id: 1437453:BN2145_RS20230
uniprot id: A0A0F7W038
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1437453:BN2145 RS25430
gene id: 1437453:BN2145_RS25430
uniprot id: A0A0F7W559
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1437453:BN2145 RS29795
gene id: 1437453:BN2145_RS29795
uniprot id: A0A0F7W2V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1437453:BN2145 RS05865
gene id: 1437453:BN2145_RS05865
uniprot id: A0A0F7VMA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1437453:BN2145 RS07795
gene id: 1437453:BN2145_RS07795
uniprot id: A0A0F7VLX6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1437453:BN2145 RS31160
gene id: 1437453:BN2145_RS31160
uniprot id: A0A0F7VXV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS29000
gene id: 1437453:BN2145_RS29000
uniprot id: A0A0F7W4W9
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1437453:BN2145 RS21490
gene id: 1437453:BN2145_RS21490
uniprot id: A0A0F7VSG1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1437453:BN2145 RS30910
gene id: 1437453:BN2145_RS30910
uniprot id: A0A0F7W3D1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1437453:BN2145 RS29685
gene id: 1437453:BN2145_RS29685
uniprot id: A0A0F7W594
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1437453:BN2145 RS15355
gene id: 1437453:BN2145_RS15355
uniprot id: A0A0F7VUV0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS11285
gene id: 1437453:BN2145_RS11285
uniprot id: A0A0F7VWZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1437453:BN2145 RS23640
gene id: 1437453:BN2145_RS23640
uniprot id: A0A0F7W242
names: Similarity
messages: Belongs to the UPF0303 family.

1437453:BN2145 RS22970
gene id: 1437453:BN2145_RS22970
uniprot id: A0A0F7VYR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1437453:BN2145 RS29060
gene id: 1437453:BN2145_RS29060
uniprot id: A0A0F7VWK7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1437453:BN2145 RS10640
gene id: 1437453:BN2145_RS10640
uniprot id: A0A0F7VWQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1437453:BN2145 RS14460
gene id: 1437453:BN2145_RS14460
uniprot id: A0A0F7VQG2
names: Similarity
messages: Belongs to the UPF0162 family.

1437453:BN2145 RS02225
gene id: 1437453:BN2145_RS02225
uniprot id: A0A0F7VLJ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1437453:BN2145 RS16115
gene id: 1437453:BN2145_RS16115
uniprot id: A0A0F7VRI6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1437453:BN2145 RS33580
gene id: 1437453:BN2145_RS33580
uniprot id: A0A0F7VZ51
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1437453:BN2145 RS13975
gene id: 1437453:BN2145_RS13975
uniprot id: A0A0F7VQ78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1437453:BN2145 RS02535
gene id: 1437453:BN2145_RS02535
uniprot id: A0A0F7VQI9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1437453:BN2145 RS22740
gene id: 1437453:BN2145_RS22740
uniprot id: A0A0F7W1K1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1437453:BN2145 RS07195
gene id: 1437453:BN2145_RS07195
uniprot id: A0A0F7VPY0
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS03600
gene id: 1437453:BN2145_RS03600
uniprot id: A0A0F7VNP4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1437453:BN2145 RS29380
gene id: 1437453:BN2145_RS29380
uniprot id: A0A0F7W530
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1437453:BN2145 RS05670
gene id: 1437453:BN2145_RS05670
uniprot id: A0A0F7VTU9
names: Similarity
messages: Belongs to the TPP enzyme family.

1437453:BN2145 RS38290
gene id: 1437453:BN2145_RS38290
uniprot id: A0A0F7VM25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1437453:BN2145 RS31120
gene id: 1437453:BN2145_RS31120
uniprot id: A0A0F7W041
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1437453:BN2145 RS15820
gene id: 1437453:BN2145_RS15820
uniprot id: A0A0F7VRB4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1437453:BN2145 RS07630
gene id: 1437453:BN2145_RS07630
uniprot id: A0A0F7VUT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

1437453:BN2145 RS07130
gene id: 1437453:BN2145_RS07130
uniprot id: A0A0F7VUG4
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS03655
gene id: 1437453:BN2145_RS03655
uniprot id: A0A0F7VL02
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS12845
gene id: 1437453:BN2145_RS12845
uniprot id: A0A0F7VW53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS27505
gene id: 1437453:BN2145_RS27505
uniprot id: A0A0F7W5Z1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1437453:BN2145 RS32355
gene id: 1437453:BN2145_RS32355
uniprot id: A0A0F7W8F5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437453:BN2145 RS02110
gene id: 1437453:BN2145_RS02110
uniprot id: A0A0F7VKS6
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS27005
gene id: 1437453:BN2145_RS27005
uniprot id: A0A0F7VXK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1437453:BN2145 RS16070
gene id: 1437453:BN2145_RS16070
uniprot id: A0A0F7W0A9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1437453:BN2145 RS31185
gene id: 1437453:BN2145_RS31185
uniprot id: A0A0F7VXV7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS28025
gene id: 1437453:BN2145_RS28025
uniprot id: A0A0F7W676
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1437453:BN2145 RS11955
gene id: 1437453:BN2145_RS11955
uniprot id: A0A0F7VNC4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1437453:BN2145 RS30485
gene id: 1437453:BN2145_RS30485
uniprot id: A0A0F7W368
names: Similarity
messages: Belongs to the asparagine synthetase family.

1437453:BN2145 RS23660
gene id: 1437453:BN2145_RS23660
uniprot id: A0A0F7W4G1
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

1437453:BN2145 RS16235
gene id: 1437453:BN2145_RS16235
uniprot id: A0A0F7VQ12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1437453:BN2145 RS34920
gene id: 1437453:BN2145_RS34920
uniprot id: A0A0F7W870
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS12700
gene id: 1437453:BN2145_RS12700
uniprot id: A0A0F7VT41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1437453:BN2145 RS11835
gene id: 1437453:BN2145_RS11835
uniprot id: A0A0F7VP37
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

1437453:BN2145 RS19000
gene id: 1437453:BN2145_RS19000
uniprot id: A0A0F7VR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1437453:BN2145 RS16735
gene id: 1437453:BN2145_RS16735
uniprot id: A0A0F7W0J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS27130
gene id: 1437453:BN2145_RS27130
uniprot id: A0A0F7W5R8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1437453:BN2145 RS08600
gene id: 1437453:BN2145_RS08600
uniprot id: A0A0F7VTR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1437453:BN2145 RS16175
gene id: 1437453:BN2145_RS16175
uniprot id: A0A0F7VY08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1437453:BN2145 RS08180
gene id: 1437453:BN2145_RS08180
uniprot id: A0A0F7VM35
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS17095
gene id: 1437453:BN2145_RS17095
uniprot id: A0A0F7VQC8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437453:BN2145 RS30795
gene id: 1437453:BN2145_RS30795
uniprot id: A0A0F7VZV5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1437453:BN2145 RS12885
gene id: 1437453:BN2145_RS12885
uniprot id: A0A0F7VPJ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS07570
gene id: 1437453:BN2145_RS07570
uniprot id: A0A0F7VQ50
names: Similarity
messages: Belongs to the TPP enzyme family.

1437453:BN2145 RS02250
gene id: 1437453:BN2145_RS02250
uniprot id: A0A0F7VLJ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS07185
gene id: 1437453:BN2145_RS07185
uniprot id: A0A0F7VUH1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS29905
gene id: 1437453:BN2145_RS29905
uniprot id: A0A0F7VX36
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS13970
gene id: 1437453:BN2145_RS13970
uniprot id: A0A0F7VP63
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1437453:BN2145 RS29990
gene id: 1437453:BN2145_RS29990
uniprot id: A0A0F7W733
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS08295
gene id: 1437453:BN2145_RS08295
uniprot id: A0A0F7VTK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS10985
gene id: 1437453:BN2145_RS10985
uniprot id: A0A0F7VS77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1437453:BN2145 RS16645
gene id: 1437453:BN2145_RS16645
uniprot id: A0A0F7VVM3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1437453:BN2145 RS23005
gene id: 1437453:BN2145_RS23005
uniprot id: A0A0F7VVK5
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1437453:BN2145 RS04355
gene id: 1437453:BN2145_RS04355
uniprot id: A0A0F7VLZ5
names: Similarity
messages: Belongs to the peptidase S1 family.

1437453:BN2145 RS27715
gene id: 1437453:BN2145_RS27715
uniprot id: A0A0F7W1G3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS16775
gene id: 1437453:BN2145_RS16775
uniprot id: A0A0F7VQ87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS30865
gene id: 1437453:BN2145_RS30865
uniprot id: A0A0F7VXQ3
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS22095
gene id: 1437453:BN2145_RS22095
uniprot id: A0A0F7VST9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1437453:BN2145 RS15665
gene id: 1437453:BN2145_RS15665
uniprot id: A0A0F7VR87
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1437453:BN2145 RS23855
gene id: 1437453:BN2145_RS23855
uniprot id: A0A0F7VW13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1437453:BN2145 RS16305
gene id: 1437453:BN2145_RS16305
uniprot id: A0A0F7VQ19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1437453:BN2145 RS10945
gene id: 1437453:BN2145_RS10945
uniprot id: A0A0F7VNU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1437453:BN2145 RS27045
gene id: 1437453:BN2145_RS27045
uniprot id: A0A0F7W155
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1437453:BN2145 RS13670
gene id: 1437453:BN2145_RS13670
uniprot id: A0A0F7VNZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1437453:BN2145 RS21395
gene id: 1437453:BN2145_RS21395
uniprot id: A0A0F7W326
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS16520
gene id: 1437453:BN2145_RS16520
uniprot id: A0A0F7VVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS15035
gene id: 1437453:BN2145_RS15035
uniprot id: A0A0F7VQR4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1437453:BN2145 RS31210
gene id: 1437453:BN2145_RS31210
uniprot id: A0A0F7VXW4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

1437453:BN2145 RS30710
gene id: 1437453:BN2145_RS30710
uniprot id: A0A0F7W3A0
names: Similarity
messages: Belongs to the IMPACT family.

1437453:BN2145 RS25615
gene id: 1437453:BN2145_RS25615
uniprot id: A0A0F7W073
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1437453:BN2145 RS08405
gene id: 1437453:BN2145_RS08405
uniprot id: A0A0F7VQP9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1437453:BN2145 RS22535
gene id: 1437453:BN2145_RS22535
uniprot id: A0A0F7W3M4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1437453:BN2145 RS28035
gene id: 1437453:BN2145_RS28035
uniprot id: A0A0F7W1K9
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1437453:BN2145 RS29050
gene id: 1437453:BN2145_RS29050
uniprot id: A0A0F7W4X5
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1437453:BN2145 RS11585
gene id: 1437453:BN2145_RS11585
uniprot id: A0A0F7VX64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1437453:BN2145 RS16740
gene id: 1437453:BN2145_RS16740
uniprot id: A0A0F7VYC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1437453:BN2145 RS22230
gene id: 1437453:BN2145_RS22230
uniprot id: A0A0F7W1C8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1437453:BN2145 RS31385
gene id: 1437453:BN2145_RS31385
uniprot id: A0A0F7VY19
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1437453:BN2145 RS24690
gene id: 1437453:BN2145_RS24690
uniprot id: A0A0F7VZQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1437453:BN2145 RS24095
gene id: 1437453:BN2145_RS24095
uniprot id: A0A0F7VTT6
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS24850
gene id: 1437453:BN2145_RS24850
uniprot id: A0A0F7VU95
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1437453:BN2145 RS34910
gene id: 1437453:BN2145_RS34910
uniprot id: A0A0F7W260
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1437453:BN2145 RS08220
gene id: 1437453:BN2145_RS08220
uniprot id: A0A0F7VTJ3
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1437453:BN2145 RS33390
gene id: 1437453:BN2145_RS33390
uniprot id: A0A0F7W7B6
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1437453:BN2145 RS20575
gene id: 1437453:BN2145_RS20575
uniprot id: A0A0F7VRZ0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1437453:BN2145 RS18405
gene id: 1437453:BN2145_RS18405
uniprot id: A0A0F7W1R1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS15870
gene id: 1437453:BN2145_RS15870
uniprot id: A0A0F7VRE8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1437453:BN2145 RS19360
gene id: 1437453:BN2145_RS19360
uniprot id: A0A0F7VRB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1437453:BN2145 RS21125
gene id: 1437453:BN2145_RS21125
uniprot id: A0A0F7VSD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1437453:BN2145 RS28750
gene id: 1437453:BN2145_RS28750
uniprot id: A0A0F7W2B9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1437453:BN2145 RS32375
gene id: 1437453:BN2145_RS32375
uniprot id: A0A0F7W0R1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1437453:BN2145 RS07585
gene id: 1437453:BN2145_RS07585
uniprot id: A0A0F7VT86
names: Similarity
messages: Belongs to the peptidase C56 family.

1437453:BN2145 RS18690
gene id: 1437453:BN2145_RS18690
uniprot id: A0A0F7VR17
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS21245
gene id: 1437453:BN2145_RS21245
uniprot id: A0A0F7VUN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS29550
gene id: 1437453:BN2145_RS29550
uniprot id: A0A0F7VZ23
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1437453:BN2145 RS17130
gene id: 1437453:BN2145_RS17130
uniprot id: A0A0F7W0U5
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1437453:BN2145 RS04700
gene id: 1437453:BN2145_RS04700
uniprot id: A0A0F7VL70
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1437453:BN2145 RS23355
gene id: 1437453:BN2145_RS23355
uniprot id: A0A0F7VZ03
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1437453:BN2145 RS07790
gene id: 1437453:BN2145_RS07790
uniprot id: A0A0F7VQA0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS25245
gene id: 1437453:BN2145_RS25245
uniprot id: A0A0F7VZZ7
names: Subcellular Location Annotation
messages: Cell membrane

1437453:BN2145 RS11300
gene id: 1437453:BN2145_RS11300
uniprot id: A0A0F7VN52
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1437453:BN2145 RS31315
gene id: 1437453:BN2145_RS31315
uniprot id: A0A0F7W072
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1437453:BN2145 RS33920
gene id: 1437453:BN2145_RS33920
uniprot id: A0A0F7W1M8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1437453:BN2145 RS25305
gene id: 1437453:BN2145_RS25305
uniprot id: A0A0F7VWM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS24680
gene id: 1437453:BN2145_RS24680
uniprot id: A0A0F7W4X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1437453:BN2145 RS12710
gene id: 1437453:BN2145_RS12710
uniprot id: A0A0F7VPF7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1437453:BN2145 RS20000
gene id: 1437453:BN2145_RS20000
uniprot id: A0A0F7W014
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS17755
gene id: 1437453:BN2145_RS17755
uniprot id: A0A0F7W156
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1437453:BN2145 RS08825
gene id: 1437453:BN2145_RS08825
uniprot id: A0A0F7VN83
names: Similarity
messages: Belongs to the CdaR family.

1437453:BN2145 RS11525
gene id: 1437453:BN2145_RS11525
uniprot id: A0A0F7VN84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1437453:BN2145 RS17815
gene id: 1437453:BN2145_RS17815
uniprot id: A0A0F7VWB7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS15670
gene id: 1437453:BN2145_RS15670
uniprot id: A0A0F7W066
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1437453:BN2145 RS14870
gene id: 1437453:BN2145_RS14870
uniprot id: A0A0F7VX67
names: Similarity
messages: Belongs to the GSP E family.

1437453:BN2145 RS26865
gene id: 1437453:BN2145_RS26865
uniprot id: A0A0F7W119
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS27825
gene id: 1437453:BN2145_RS27825
uniprot id: A0A0F7VY18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1437453:BN2145 RS34080
gene id: 1437453:BN2145_RS34080
uniprot id: A0A0F7W7U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

1437453:BN2145 RS27660
gene id: 1437453:BN2145_RS27660
uniprot id: A0A0F7W412
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1437453:BN2145 RS11990
gene id: 1437453:BN2145_RS11990
uniprot id: A0A0F7VXF5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1437453:BN2145 RS07105
gene id: 1437453:BN2145_RS07105
uniprot id: A0A0F7VUG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1437453:BN2145 RS20130
gene id: 1437453:BN2145_RS20130
uniprot id: A0A0F7VU05
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1437453:BN2145 RS12990
gene id: 1437453:BN2145_RS12990
uniprot id: A0A0F7VT89
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS28170
gene id: 1437453:BN2145_RS28170
uniprot id: A0A0F7VY74
names: Similarity
messages: Belongs to the asp23 family.

1437453:BN2145 RS26070
gene id: 1437453:BN2145_RS26070
uniprot id: A0A0F7W5G8
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS34860
gene id: 1437453:BN2145_RS34860
uniprot id: A0A0F7W254
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1437453:BN2145 RS33360
gene id: 1437453:BN2145_RS33360
uniprot id: A0A0F7W914
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1437453:BN2145 RS11345
gene id: 1437453:BN2145_RS11345
uniprot id: A0A0F7VSG8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1437453:BN2145 RS16390
gene id: 1437453:BN2145_RS16390
uniprot id: A0A0F7VQ27
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1437453:BN2145 RS16150
gene id: 1437453:BN2145_RS16150
uniprot id: A0A0F7VVD5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1437453:BN2145 RS32170
gene id: 1437453:BN2145_RS32170
uniprot id: A0A0F7W475
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS04435
gene id: 1437453:BN2145_RS04435
uniprot id: A0A0F7VM00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS34720
gene id: 1437453:BN2145_RS34720
uniprot id: A0A0F7W9R3
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1437453:BN2145 RS15315
gene id: 1437453:BN2145_RS15315
uniprot id: A0A0F7VR15
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS05270
gene id: 1437453:BN2145_RS05270
uniprot id: A0A0F7VTI4
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1437453:BN2145 RS20865
gene id: 1437453:BN2145_RS20865
uniprot id: A0A0F7VXW9
names: Subcellular Location Annotation
messages: Cytoplasm

1437453:BN2145 RS31525
gene id: 1437453:BN2145_RS31525
uniprot id: A0A0F7W828
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS11365
gene id: 1437453:BN2145_RS11365
uniprot id: A0A0F7VVA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS07490
gene id: 1437453:BN2145_RS07490
uniprot id: A0A0F7VMS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS24700
gene id: 1437453:BN2145_RS24700
uniprot id: A0A0F7VWB9
names: Similarity
messages: Belongs to the FPG family.

1437453:BN2145 RS19495
gene id: 1437453:BN2145_RS19495
uniprot id: A0A0F7VXB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1437453:BN2145 RS21165
gene id: 1437453:BN2145_RS21165
uniprot id: A0A0F7W0S4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1437453:BN2145 RS07305
gene id: 1437453:BN2145_RS07305
uniprot id: A0A0F7VUJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1437453:BN2145 RS21955
gene id: 1437453:BN2145_RS21955
uniprot id: A0A0F7VSR5
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1437453:BN2145 RS11130
gene id: 1437453:BN2145_RS11130
uniprot id: A0A0F7VWY5
names: Similarity
messages: Belongs to the WXG100 family.

1437453:BN2145 RS24745
gene id: 1437453:BN2145_RS24745
uniprot id: A0A0F7W2K1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1437453:BN2145 RS15365
gene id: 1437453:BN2145_RS15365
uniprot id: A0A0F7VR25
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1437453:BN2145 RS28110
gene id: 1437453:BN2145_RS28110
uniprot id: A0A0F7W1L8
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS17300
gene id: 1437453:BN2145_RS17300
uniprot id: A0A0F7VQE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS29100
gene id: 1437453:BN2145_RS29100
uniprot id: A0A0F7W6Q9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1437453:BN2145 RS25190
gene id: 1437453:BN2145_RS25190
uniprot id: A0A0F7W2T7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1437453:BN2145 RS03320
gene id: 1437453:BN2145_RS03320
uniprot id: A0A0F7VSL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS32580
gene id: 1437453:BN2145_RS32580
uniprot id: A0A0F7W6V9
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

1437453:BN2145 RS28835
gene id: 1437453:BN2145_RS28835
uniprot id: A0A0F7VYQ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1437453:BN2145 RS20340
gene id: 1437453:BN2145_RS20340
uniprot id: A0A0F7VU54
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS17615
gene id: 1437453:BN2145_RS17615
uniprot id: A0A0F7W125
names: Similarity
messages: Belongs to the UPF0145 family.

1437453:BN2145 RS27340
gene id: 1437453:BN2145_RS27340
uniprot id: A0A0F7W3V7
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS03030
gene id: 1437453:BN2145_RS03030
uniprot id: A0A0F7VLP7
names: Similarity
messages: Belongs to the thioesterase family.

1437453:BN2145 RS16960
gene id: 1437453:BN2145_RS16960
uniprot id: A0A0F7VYF2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1437453:BN2145 RS13065
gene id: 1437453:BN2145_RS13065
uniprot id: A0A0F7VTC7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1437453:BN2145 RS32550
gene id: 1437453:BN2145_RS32550
uniprot id: A0A0F7W8M6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1437453:BN2145 RS28055
gene id: 1437453:BN2145_RS28055
uniprot id: A0A0F7W486
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1437453:BN2145 RS09330
gene id: 1437453:BN2145_RS09330
uniprot id: A0A0F7VMG5
names: Similarity
messages: Belongs to the terpene synthase family.

1437453:BN2145 RS09880
gene id: 1437453:BN2145_RS09880
uniprot id: A0A0F7VW46
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

1437453:BN2145 RS09670
gene id: 1437453:BN2145_RS09670
uniprot id: A0A0F7VMJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS15755
gene id: 1437453:BN2145_RS15755
uniprot id: A0A0F7VXU1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1437453:BN2145 RS16090
gene id: 1437453:BN2145_RS16090
uniprot id: A0A0F7VRI1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS17710
gene id: 1437453:BN2145_RS17710
uniprot id: A0A0F7VQI4
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1437453:BN2145 RS09180
gene id: 1437453:BN2145_RS09180
uniprot id: A0A0F7VME8
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1437453:BN2145 RS16230
gene id: 1437453:BN2145_RS16230
uniprot id: A0A0F7VVE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1437453:BN2145 RS29760
gene id: 1437453:BN2145_RS29760
uniprot id: A0A0F7W6Y9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1437453:BN2145 RS28115
gene id: 1437453:BN2145_RS28115
uniprot id: A0A0F7VW59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

1437453:BN2145 RS28540
gene id: 1437453:BN2145_RS28540
uniprot id: A0A0F7W4Q9
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1437453:BN2145 RS19670
gene id: 1437453:BN2145_RS19670
uniprot id: A0A0F7VXE7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1437453:BN2145 RS24035
gene id: 1437453:BN2145_RS24035
uniprot id: A0A0F7W4J7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS18235
gene id: 1437453:BN2145_RS18235
uniprot id: A0A0F7VZ79
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1437453:BN2145 RS18475
gene id: 1437453:BN2145_RS18475
uniprot id: A0A0F7VT91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1437453:BN2145 RS27020
gene id: 1437453:BN2145_RS27020
uniprot id: A0A0F7W151
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1437453:BN2145 RS17855
gene id: 1437453:BN2145_RS17855
uniprot id: A0A0F7W172
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS03180
gene id: 1437453:BN2145_RS03180
uniprot id: A0A0F7VLQ8
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS19435
gene id: 1437453:BN2145_RS19435
uniprot id: A0A0F7VZS5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1437453:BN2145 RS20570
gene id: 1437453:BN2145_RS20570
uniprot id: A0A0F7VXR5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1437453:BN2145 RS14735
gene id: 1437453:BN2145_RS14735
uniprot id: A0A0F7VZJ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1437453:BN2145 RS35595
gene id: 1437453:BN2145_RS35595
uniprot id: A0A0F7VT77
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1437453:BN2145 RS11135
gene id: 1437453:BN2145_RS11135
uniprot id: A0A0F7VV67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

1437453:BN2145 RS09715
gene id: 1437453:BN2145_RS09715
uniprot id: A0A0F7VRD8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1437453:BN2145 RS21320
gene id: 1437453:BN2145_RS21320
uniprot id: A0A0F7W314
names: Subcellular Location Annotation
messages: Cell membrane

1437453:BN2145 RS16365
gene id: 1437453:BN2145_RS16365
uniprot id: A0A0F7VRQ2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1437453:BN2145 RS06540
gene id: 1437453:BN2145_RS06540
uniprot id: A0A0F7VMG4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1437453:BN2145 RS30370
gene id: 1437453:BN2145_RS30370
uniprot id: A0A0F7VXF0
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1437453:BN2145 RS04660
gene id: 1437453:BN2145_RS04660
uniprot id: A0A0F7VT73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1437453:BN2145 RS09760
gene id: 1437453:BN2145_RS09760
uniprot id: A0A0F7VMK5
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS04445
gene id: 1437453:BN2145_RS04445
uniprot id: A0A0F7VRG0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1437453:BN2145 RS30225
gene id: 1437453:BN2145_RS30225
uniprot id: A0A0F7VXC0
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1437453:BN2145 RS22200
gene id: 1437453:BN2145_RS22200
uniprot id: A0A0F7W3E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1437453:BN2145 RS26285
gene id: 1437453:BN2145_RS26285
uniprot id: A0A0F7W3G1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1437453:BN2145 RS29695
gene id: 1437453:BN2145_RS29695
uniprot id: A0A0F7VWU1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1437453:BN2145 RS29480
gene id: 1437453:BN2145_RS29480
uniprot id: A0A0F7W549
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1437453:BN2145 RS07510
gene id: 1437453:BN2145_RS07510
uniprot id: A0A0F7VLV5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1437453:BN2145 RS18570
gene id: 1437453:BN2145_RS18570
uniprot id: A0A0F7VZC6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1437453:BN2145 RS07680
gene id: 1437453:BN2145_RS07680
uniprot id: A0A0F7VUT9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1437453:BN2145 RS13935
gene id: 1437453:BN2145_RS13935
uniprot id: A0A0F7VWP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1437453:BN2145 RS13640
gene id: 1437453:BN2145_RS13640
uniprot id: A0A0F7VTW8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1437453:BN2145 RS29955
gene id: 1437453:BN2145_RS29955
uniprot id: A0A0F7VX78
names: Subcellular Location Annotation
messages: Membrane

1437453:BN2145 RS14505
gene id: 1437453:BN2145_RS14505
uniprot id: A0A0F7VPD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS07310
gene id: 1437453:BN2145_RS07310
uniprot id: A0A0F7VT34
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

1437453:BN2145 RS25220
gene id: 1437453:BN2145_RS25220
uniprot id: A0A0F7VZZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1437453:BN2145 RS14070
gene id: 1437453:BN2145_RS14070
uniprot id: A0A0F7VU48
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1437453:BN2145 RS19990
gene id: 1437453:BN2145_RS19990
uniprot id: A0A0F7VTY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

1437453:BN2145 RS12730
gene id: 1437453:BN2145_RS12730
uniprot id: A0A0F7VNK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1437453:BN2145 RS12775
gene id: 1437453:BN2145_RS12775
uniprot id: A0A0F7VT54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.