1433513:D7D53 RS00070
gene id: 1433513:D7D53_RS00070
uniprot id: A0A387B136
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1433513:D7D53 RS03950
gene id: 1433513:D7D53_RS03950
uniprot id: A0A387B357
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS09360
gene id: 1433513:D7D53_RS09360
uniprot id: A0A387B646
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1433513:D7D53 RS05750
gene id: 1433513:D7D53_RS05750
uniprot id: A0A387B2N3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

1433513:D7D53 RS04575
gene id: 1433513:D7D53_RS04575
uniprot id: A0A387BAT2
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1433513:D7D53 RS02805
gene id: 1433513:D7D53_RS02805
uniprot id: A0A387AZE6
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS00715
gene id: 1433513:D7D53_RS00715
uniprot id: A0A387AVS9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS08740
gene id: 1433513:D7D53_RS08740
uniprot id: A0A387AZC7
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS00030
gene id: 1433513:D7D53_RS00030
uniprot id: A0A387AZX4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1433513:D7D53 RS08390
gene id: 1433513:D7D53_RS08390
uniprot id: A0A387B2D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

1433513:D7D53 RS01655
gene id: 1433513:D7D53_RS01655
uniprot id: A0A387AW54
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1433513:D7D53 RS05735
gene id: 1433513:D7D53_RS05735
uniprot id: A0A387B433
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1433513:D7D53 RS03130
gene id: 1433513:D7D53_RS03130
uniprot id: A0A387B2Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1433513:D7D53 RS05030
gene id: 1433513:D7D53_RS05030
uniprot id: A0A387B2A0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1433513:D7D53 RS07610
gene id: 1433513:D7D53_RS07610
uniprot id: A0A387B5Q2
names: Similarity
messages: Belongs to the acylphosphatase family.

1433513:D7D53 RS09690
gene id: 1433513:D7D53_RS09690
uniprot id: A0A387B4Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS02475
gene id: 1433513:D7D53_RS02475
uniprot id: A0A387B134
names: Similarity
messages: Belongs to the acetyltransferase family.

1433513:D7D53 RS04590
gene id: 1433513:D7D53_RS04590
uniprot id: A0A387B089
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS06530
gene id: 1433513:D7D53_RS06530
uniprot id: A0A387B308
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1433513:D7D53 RS02790
gene id: 1433513:D7D53_RS02790
uniprot id: A0A387B9M3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1433513:D7D53 RS05340
gene id: 1433513:D7D53_RS05340
uniprot id: A0A387B0M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS05440
gene id: 1433513:D7D53_RS05440
uniprot id: A0A387AXW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

1433513:D7D53 RS00405
gene id: 1433513:D7D53_RS00405
uniprot id: A0A387AVN7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1433513:D7D53 RS03860
gene id: 1433513:D7D53_RS03860
uniprot id: A0A387AZX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS05080
gene id: 1433513:D7D53_RS05080
uniprot id: A0A387B0M4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1433513:D7D53 RS01770
gene id: 1433513:D7D53_RS01770
uniprot id: A0A387B0S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1433513:D7D53 RS09915
gene id: 1433513:D7D53_RS09915
uniprot id: A0A387AZW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1433513:D7D53 RS00060
gene id: 1433513:D7D53_RS00060
uniprot id: A0A387AY47
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1433513:D7D53 RS01505
gene id: 1433513:D7D53_RS01505
uniprot id: A0A387AYW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1433513:D7D53 RS05345
gene id: 1433513:D7D53_RS05345
uniprot id: A0A387AXU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS02950
gene id: 1433513:D7D53_RS02950
uniprot id: A0A387B9Q8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1433513:D7D53 RS00925
gene id: 1433513:D7D53_RS00925
uniprot id: A0A387AYI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1433513:D7D53 RS07470
gene id: 1433513:D7D53_RS07470
uniprot id: A0A387B3N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1433513:D7D53 RS09315
gene id: 1433513:D7D53_RS09315
uniprot id: A0A387BDE3
names: Similarity
messages: Belongs to the CtsR family.

1433513:D7D53 RS05675
gene id: 1433513:D7D53_RS05675
uniprot id: A0A387B0S5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1433513:D7D53 RS05430
gene id: 1433513:D7D53_RS05430
uniprot id: A0A387BB94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

1433513:D7D53 RS01160
gene id: 1433513:D7D53_RS01160
uniprot id: A0A387AYQ3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1433513:D7D53 RS08115
gene id: 1433513:D7D53_RS08115
uniprot id: A0A387B3Z8
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
messages: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.

1433513:D7D53 RS01585
gene id: 1433513:D7D53_RS01585
uniprot id: A0A387B0P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1433513:D7D53 RS05840
gene id: 1433513:D7D53_RS05840
uniprot id: A0A387B455
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1433513:D7D53 RS09185
gene id: 1433513:D7D53_RS09185
uniprot id: A0A387B2T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS09180
gene id: 1433513:D7D53_RS09180
uniprot id: A0A387B6D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1433513:D7D53 RS01255
gene id: 1433513:D7D53_RS01255
uniprot id: A0A387AVZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS05960
gene id: 1433513:D7D53_RS05960
uniprot id: A0A387B2S3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1433513:D7D53 RS06215
gene id: 1433513:D7D53_RS06215
uniprot id: A0A387AY88
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1433513:D7D53 RS02595
gene id: 1433513:D7D53_RS02595
uniprot id: A0A387AZA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1433513:D7D53 RS09800
gene id: 1433513:D7D53_RS09800
uniprot id: A0A387AZT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1433513:D7D53 RS03100
gene id: 1433513:D7D53_RS03100
uniprot id: A0A387B2N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1433513:D7D53 RS04800
gene id: 1433513:D7D53_RS04800
uniprot id: A0A387AXK6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

1433513:D7D53 RS01080
gene id: 1433513:D7D53_RS01080
uniprot id: A0A387AYL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1433513:D7D53 RS02755
gene id: 1433513:D7D53_RS02755
uniprot id: A0A387AZD5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1433513:D7D53 RS00460
gene id: 1433513:D7D53_RS00460
uniprot id: A0A387AVP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1433513:D7D53 RS01095
gene id: 1433513:D7D53_RS01095
uniprot id: A0A387B1K5
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS07160
gene id: 1433513:D7D53_RS07160
uniprot id: A0A387B5G6
names: Similarity
messages: Belongs to the glutamine synthetase family.

1433513:D7D53 RS04670
gene id: 1433513:D7D53_RS04670
uniprot id: A0A387B236
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1433513:D7D53 RS01845
gene id: 1433513:D7D53_RS01845
uniprot id: A0A387B203
names: Similarity
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Homotetramer.

1433513:D7D53 RS03185
gene id: 1433513:D7D53_RS03185
uniprot id: A0A387B2R6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1433513:D7D53 RS05385
gene id: 1433513:D7D53_RS05385
uniprot id: A0A387B2K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1433513:D7D53 RS09055
gene id: 1433513:D7D53_RS09055
uniprot id: A0A387AZG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1433513:D7D53 RS06965
gene id: 1433513:D7D53_RS06965
uniprot id: A0A387BC71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1433513:D7D53 RS07315
gene id: 1433513:D7D53_RS07315
uniprot id: A0A387B5J8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1433513:D7D53 RS03300
gene id: 1433513:D7D53_RS03300
uniprot id: A0A387AZX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1433513:D7D53 RS05980
gene id: 1433513:D7D53_RS05980
uniprot id: A0A387AY52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1433513:D7D53 RS04945
gene id: 1433513:D7D53_RS04945
uniprot id: A0A387AXN4
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1433513:D7D53 RS00815
gene id: 1433513:D7D53_RS00815
uniprot id: A0A387AVU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS03845
gene id: 1433513:D7D53_RS03845
uniprot id: A0A387BAC8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a set of proteins in which some residues (ACT_SITE, NP_BIND, REGION and BINDING) are not conserved.

1433513:D7D53 RS07870
gene id: 1433513:D7D53_RS07870
uniprot id: A0A387AZ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1433513:D7D53 RS09955
gene id: 1433513:D7D53_RS09955
uniprot id: A0A387AZV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1433513:D7D53 RS01060
gene id: 1433513:D7D53_RS01060
uniprot id: A0A387B1L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1433513:D7D53 RS09600
gene id: 1433513:D7D53_RS09600
uniprot id: A0A387B639
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1433513:D7D53 RS06275
gene id: 1433513:D7D53_RS06275
uniprot id: A0A387AY98
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1433513:D7D53 RS09145
gene id: 1433513:D7D53_RS09145
uniprot id: A0A387B5T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1433513:D7D53 RS03115
gene id: 1433513:D7D53_RS03115
uniprot id: A0A387AWR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

1433513:D7D53 RS04400
gene id: 1433513:D7D53_RS04400
uniprot id: A0A387B239
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1433513:D7D53 RS01105
gene id: 1433513:D7D53_RS01105
uniprot id: A0A387AYP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS01860
gene id: 1433513:D7D53_RS01860
uniprot id: A0A387B0M5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1433513:D7D53 RS04785
gene id: 1433513:D7D53_RS04785
uniprot id: A0A387B297
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS09945
gene id: 1433513:D7D53_RS09945
uniprot id: A0A387BDW7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1433513:D7D53 RS07900
gene id: 1433513:D7D53_RS07900
uniprot id: A0A387B3Q0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1433513:D7D53 RS02065
gene id: 1433513:D7D53_RS02065
uniprot id: A0A387AWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EsaA family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS01310
gene id: 1433513:D7D53_RS01310
uniprot id: A0A387AYQ1
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS03650
gene id: 1433513:D7D53_RS03650
uniprot id: A0A387AX35
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1433513:D7D53 RS07260
gene id: 1433513:D7D53_RS07260
uniprot id: A0A387B5I7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1433513:D7D53 RS03310
gene id: 1433513:D7D53_RS03310
uniprot id: A0A387B1G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1433513:D7D53 RS04360
gene id: 1433513:D7D53_RS04360
uniprot id: A0A387B3D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C40 family.
messages: Cell surface

1433513:D7D53 RS00025
gene id: 1433513:D7D53_RS00025
uniprot id: A0A387AZX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1433513:D7D53 RS06130
gene id: 1433513:D7D53_RS06130
uniprot id: A0A387B151
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1433513:D7D53 RS00915
gene id: 1433513:D7D53_RS00915
uniprot id: A0A387B0D5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1433513:D7D53 RS07835
gene id: 1433513:D7D53_RS07835
uniprot id: A0A387B253
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1433513:D7D53 RS00395
gene id: 1433513:D7D53_RS00395
uniprot id: A0A387B867
names: Similarity
messages: Belongs to the UPF0236 family.

1433513:D7D53 RS03340
gene id: 1433513:D7D53_RS03340
uniprot id: A0A387AWY2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1433513:D7D53 RS07620
gene id: 1433513:D7D53_RS07620
uniprot id: A0A387B3K0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1433513:D7D53 RS07590
gene id: 1433513:D7D53_RS07590
uniprot id: A0A387B1N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1433513:D7D53 RS00065
gene id: 1433513:D7D53_RS00065
uniprot id: A0A387AZI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1433513:D7D53 RS07615
gene id: 1433513:D7D53_RS07615
uniprot id: A0A387B218
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1433513:D7D53 RS06055
gene id: 1433513:D7D53_RS06055
uniprot id: A0A387B496
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1433513:D7D53 RS09330
gene id: 1433513:D7D53_RS09330
uniprot id: A0A387B2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1433513:D7D53 RS00475
gene id: 1433513:D7D53_RS00475
uniprot id: A0A387B191
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1433513:D7D53 RS00075
gene id: 1433513:D7D53_RS00075
uniprot id: A0A387B7Z9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1433513:D7D53 RS01500
gene id: 1433513:D7D53_RS01500
uniprot id: A0A387B2K7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1433513:D7D53 RS06830
gene id: 1433513:D7D53_RS06830
uniprot id: A0A387B1A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1433513:D7D53 RS07840
gene id: 1433513:D7D53_RS07840
uniprot id: A0A387B3P0
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS01485
gene id: 1433513:D7D53_RS01485
uniprot id: A0A387AYS7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1433513:D7D53 RS09380
gene id: 1433513:D7D53_RS09380
uniprot id: A0A387B2L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1433513:D7D53 RS02670
gene id: 1433513:D7D53_RS02670
uniprot id: A0A387B143
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS09910
gene id: 1433513:D7D53_RS09910
uniprot id: A0A387B2V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1433513:D7D53 RS04690
gene id: 1433513:D7D53_RS04690
uniprot id: A0A387AXJ2
names: Similarity
names: Subunit
messages: Belongs to the LacAB/RpiB family.
messages: Heteromultimeric protein consisting of LacA and LacB.

1433513:D7D53 RS08935
gene id: 1433513:D7D53_RS08935
uniprot id: A0A387B5Q4
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1433513:D7D53 RS04855
gene id: 1433513:D7D53_RS04855
uniprot id: A0A387B3M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1433513:D7D53 RS07265
gene id: 1433513:D7D53_RS07265
uniprot id: A0A387B1V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS08585
gene id: 1433513:D7D53_RS08585
uniprot id: A0A387B248
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1433513:D7D53 RS06820
gene id: 1433513:D7D53_RS06820
uniprot id: A0A387B3D7
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1433513:D7D53 RS07420
gene id: 1433513:D7D53_RS07420
uniprot id: A0A387AYT6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1433513:D7D53 RS05475
gene id: 1433513:D7D53_RS05475
uniprot id: A0A387B2H5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1433513:D7D53 RS02415
gene id: 1433513:D7D53_RS02415
uniprot id: A0A387B2A2
names: Similarity
messages: Belongs to the Gfa family.

1433513:D7D53 RS01970
gene id: 1433513:D7D53_RS01970
uniprot id: A0A387B221
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1433513:D7D53 RS07135
gene id: 1433513:D7D53_RS07135
uniprot id: A0A387AYP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1433513:D7D53 RS00005
gene id: 1433513:D7D53_RS00005
uniprot id: A0A387AY39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1433513:D7D53 RS00015
gene id: 1433513:D7D53_RS00015
uniprot id: A0A387B128
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1433513:D7D53 RS01390
gene id: 1433513:D7D53_RS01390
uniprot id: A0A387AYU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS09925
gene id: 1433513:D7D53_RS09925
uniprot id: A0A387B6N8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1433513:D7D53 RS09550
gene id: 1433513:D7D53_RS09550
uniprot id: A0A387B6H6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1433513:D7D53 RS00920
gene id: 1433513:D7D53_RS00920
uniprot id: A0A387AVV0
names: Similarity
messages: Belongs to the asp23 family.

1433513:D7D53 RS00465
gene id: 1433513:D7D53_RS00465
uniprot id: A0A387AYA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1433513:D7D53 RS06110
gene id: 1433513:D7D53_RS06110
uniprot id: A0A387B0Z9
names: Similarity
messages: Belongs to the YggT family.

1433513:D7D53 RS04145
gene id: 1433513:D7D53_RS04145
uniprot id: A0A387B391
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1433513:D7D53 RS07545
gene id: 1433513:D7D53_RS07545
uniprot id: A0A387AYV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1433513:D7D53 RS05780
gene id: 1433513:D7D53_RS05780
uniprot id: A0A387B0U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1433513:D7D53 RS09895
gene id: 1433513:D7D53_RS09895
uniprot id: A0A387BDV9
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1433513:D7D53 RS04870
gene id: 1433513:D7D53_RS04870
uniprot id: A0A387B272
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1433513:D7D53 RS08895
gene id: 1433513:D7D53_RS08895
uniprot id: A0A387AZF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1433513:D7D53 RS05755
gene id: 1433513:D7D53_RS05755
uniprot id: A0A387B447
names: Similarity
messages: Belongs to the UPF0213 family.

1433513:D7D53 RS09960
gene id: 1433513:D7D53_RS09960
uniprot id: A0A387B2V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1433513:D7D53 RS09430
gene id: 1433513:D7D53_RS09430
uniprot id: A0A387B2M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS04695
gene id: 1433513:D7D53_RS04695
uniprot id: A0A387B0A9
names: Similarity
names: Subunit
messages: Belongs to the LacAB/RpiB family.
messages: Heteromultimeric protein consisting of LacA and LacB.

1433513:D7D53 RS03520
gene id: 1433513:D7D53_RS03520
uniprot id: A0A387B3M8
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1433513:D7D53 RS07845
gene id: 1433513:D7D53_RS07845
uniprot id: A0A387B574
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS02485
gene id: 1433513:D7D53_RS02485
uniprot id: A0A387AZ90
names: Similarity
messages: Belongs to the ArsC family.

1433513:D7D53 RS08235
gene id: 1433513:D7D53_RS08235
uniprot id: A0A387BCU6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1433513:D7D53 RS00795
gene id: 1433513:D7D53_RS00795
uniprot id: A0A387B006
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS00940
gene id: 1433513:D7D53_RS00940
uniprot id: A0A387B2B0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1433513:D7D53 RS01020
gene id: 1433513:D7D53_RS01020
uniprot id: A0A387B0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1433513:D7D53 RS09410
gene id: 1433513:D7D53_RS09410
uniprot id: A0A387B656
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1433513:D7D53 RS07425
gene id: 1433513:D7D53_RS07425
uniprot id: A0A387B1L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1433513:D7D53 RS04850
gene id: 1433513:D7D53_RS04850
uniprot id: A0A387AXL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1433513:D7D53 RS02715
gene id: 1433513:D7D53_RS02715
uniprot id: A0A387B366
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1433513:D7D53 RS05480
gene id: 1433513:D7D53_RS05480
uniprot id: A0A387B3Z6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS03135
gene id: 1433513:D7D53_RS03135
uniprot id: A0A387B3F4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS00890
gene id: 1433513:D7D53_RS00890
uniprot id: A0A387B2A1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1433513:D7D53 RS09230
gene id: 1433513:D7D53_RS09230
uniprot id: A0A387B5X7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1433513:D7D53 RS04740
gene id: 1433513:D7D53_RS04740
uniprot id: A0A387AXK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1433513:D7D53 RS08750
gene id: 1433513:D7D53_RS08750
uniprot id: A0A387AZC2
names: Subcellular Location Annotation
messages: Cytoplasm

1433513:D7D53 RS02430
gene id: 1433513:D7D53_RS02430
uniprot id: A0A387AWG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1433513:D7D53 RS09825
gene id: 1433513:D7D53_RS09825
uniprot id: A0A387B6L8
names: Similarity
messages: Belongs to the ArsC family.

1433513:D7D53 RS05110
gene id: 1433513:D7D53_RS05110
uniprot id: A0A387AXR0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1433513:D7D53 RS06940
gene id: 1433513:D7D53_RS06940
uniprot id: A0A387B4P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1433513:D7D53 RS03345
gene id: 1433513:D7D53_RS03345
uniprot id: A0A387B2U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1433513:D7D53 RS02375
gene id: 1433513:D7D53_RS02375
uniprot id: A0A387B114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS03960
gene id: 1433513:D7D53_RS03960
uniprot id: A0A387B1W4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1433513:D7D53 RS00135
gene id: 1433513:D7D53_RS00135
uniprot id: A0A387B809
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1433513:D7D53 RS09255
gene id: 1433513:D7D53_RS09255
uniprot id: A0A387BDD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1433513:D7D53 RS08400
gene id: 1433513:D7D53_RS08400
uniprot id: A0A387B5E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS05955
gene id: 1433513:D7D53_RS05955
uniprot id: A0A387B123
names: Similarity
messages: Belongs to the RutC family.

1433513:D7D53 RS09905
gene id: 1433513:D7D53_RS09905
uniprot id: A0A387AZV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1433513:D7D53 RS07515
gene id: 1433513:D7D53_RS07515
uniprot id: A0A387B511
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily.
messages: Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.

1433513:D7D53 RS03980
gene id: 1433513:D7D53_RS03980
uniprot id: A0A387AX79
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1433513:D7D53 RS09205
gene id: 1433513:D7D53_RS09205
uniprot id: A0A387B4H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1433513:D7D53 RS02420
gene id: 1433513:D7D53_RS02420
uniprot id: A0A387B9D9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1433513:D7D53 RS09295
gene id: 1433513:D7D53_RS09295
uniprot id: A0A387B314
names: Similarity
messages: Belongs to the UPF0045 family.

1433513:D7D53 RS03825
gene id: 1433513:D7D53_RS03825
uniprot id: A0A387B3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1433513:D7D53 RS08465
gene id: 1433513:D7D53_RS08465
uniprot id: A0A387AZ87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1433513:D7D53 RS09890
gene id: 1433513:D7D53_RS09890
uniprot id: A0A387B6F1
names: Similarity
messages: Belongs to the acetyltransferase family.

1433513:D7D53 RS07800
gene id: 1433513:D7D53_RS07800
uniprot id: A0A387B3V4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1433513:D7D53 RS08335
gene id: 1433513:D7D53_RS08335
uniprot id: A0A387B5Z8
names: Function
messages: Required for transformation and DNA binding.

1433513:D7D53 RS09370
gene id: 1433513:D7D53_RS09370
uniprot id: A0A387B4K0
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1433513:D7D53 RS04825
gene id: 1433513:D7D53_RS04825
uniprot id: A0A387B3M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1433513:D7D53 RS08515
gene id: 1433513:D7D53_RS08515
uniprot id: A0A387BCZ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1433513:D7D53 RS01025
gene id: 1433513:D7D53_RS01025
uniprot id: A0A387AVW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1433513:D7D53 RS04415
gene id: 1433513:D7D53_RS04415
uniprot id: A0A387AXE5
names: Similarity
messages: Belongs to the transposase 7 family.

1433513:D7D53 RS08270
gene id: 1433513:D7D53_RS08270
uniprot id: A0A387B5Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1433513:D7D53 RS01615
gene id: 1433513:D7D53_RS01615
uniprot id: A0A387B1W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

1433513:D7D53 RS03140
gene id: 1433513:D7D53_RS03140
uniprot id: A0A387AZR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1433513:D7D53 RS00010
gene id: 1433513:D7D53_RS00010
uniprot id: A0A387AZG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1433513:D7D53 RS00485
gene id: 1433513:D7D53_RS00485
uniprot id: A0A387AYB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1433513:D7D53 RS00480
gene id: 1433513:D7D53_RS00480
uniprot id: A0A387B219
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS04810
gene id: 1433513:D7D53_RS04810
uniprot id: A0A387B4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1433513:D7D53 RS00455
gene id: 1433513:D7D53_RS00455
uniprot id: A0A387B045
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1433513:D7D53 RS09155
gene id: 1433513:D7D53_RS09155
uniprot id: A0A387B4F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1433513:D7D53 RS07235
gene id: 1433513:D7D53_RS07235
uniprot id: A0A387B3K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1433513:D7D53 RS04515
gene id: 1433513:D7D53_RS04515
uniprot id: A0A387B209
names: Similarity
messages: Belongs to the zeta toxin family.

1433513:D7D53 RS09620
gene id: 1433513:D7D53_RS09620
uniprot id: A0A387B696
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1433513:D7D53 RS01515
gene id: 1433513:D7D53_RS01515
uniprot id: A0A387B1U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1433513:D7D53 RS06115
gene id: 1433513:D7D53_RS06115
uniprot id: A0A387AY69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1433513:D7D53 RS04705
gene id: 1433513:D7D53_RS04705
uniprot id: A0A387B3J3
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS08295
gene id: 1433513:D7D53_RS08295
uniprot id: A0A387BCV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1433513:D7D53 RS04765
gene id: 1433513:D7D53_RS04765
uniprot id: A0A387B0H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1433513:D7D53 RS00020
gene id: 1433513:D7D53_RS00020
uniprot id: A0A387B7Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1433513:D7D53 RS08745
gene id: 1433513:D7D53_RS08745
uniprot id: A0A387B281
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS06255
gene id: 1433513:D7D53_RS06255
uniprot id: A0A387B361
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1433513:D7D53 RS02910
gene id: 1433513:D7D53_RS02910
uniprot id: A0A387AWN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Ycf16 family.
messages: Membrane

1433513:D7D53 RS09475
gene id: 1433513:D7D53_RS09475
uniprot id: A0A387AZN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS08045
gene id: 1433513:D7D53_RS08045
uniprot id: A0A387B596
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS00055
gene id: 1433513:D7D53_RS00055
uniprot id: A0A387B1S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1433513:D7D53 RS08220
gene id: 1433513:D7D53_RS08220
uniprot id: A0A387B2A4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1433513:D7D53 RS00215
gene id: 1433513:D7D53_RS00215
uniprot id: A0A387AVL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1433513:D7D53 RS00470
gene id: 1433513:D7D53_RS00470
uniprot id: A0A387AVQ8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1433513:D7D53 RS08525
gene id: 1433513:D7D53_RS08525
uniprot id: A0A387AZ97
names: Similarity
messages: Belongs to the TelA family.

1433513:D7D53 RS06325
gene id: 1433513:D7D53_RS06325
uniprot id: A0A387B6F2
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS09025
gene id: 1433513:D7D53_RS09025
uniprot id: A0A387B483
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1433513:D7D53 RS05790
gene id: 1433513:D7D53_RS05790
uniprot id: A0A387B442
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1433513:D7D53 RS03530
gene id: 1433513:D7D53_RS03530
uniprot id: A0A387B1J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1433513:D7D53 RS05365
gene id: 1433513:D7D53_RS05365
uniprot id: A0A387B2F5
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1433513:D7D53 RS00710
gene id: 1433513:D7D53_RS00710
uniprot id: A0A387B098
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1433513:D7D53 RS05405
gene id: 1433513:D7D53_RS05405
uniprot id: A0A387B3X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1433513:D7D53 RS00960
gene id: 1433513:D7D53_RS00960
uniprot id: A0A387B8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1433513:D7D53 RS06070
gene id: 1433513:D7D53_RS06070
uniprot id: A0A387B141
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1433513:D7D53 RS02080
gene id: 1433513:D7D53_RS02080
uniprot id: A0A387AZ65
names: Similarity
messages: Belongs to the EssB family.

1433513:D7D53 RS05140
gene id: 1433513:D7D53_RS05140
uniprot id: A0A387B2B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1433513:D7D53 RS09940
gene id: 1433513:D7D53_RS09940
uniprot id: A0A387B6G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1433513:D7D53 RS07140
gene id: 1433513:D7D53_RS07140
uniprot id: A0A387B1G8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1433513:D7D53 RS07450
gene id: 1433513:D7D53_RS07450
uniprot id: A0A387B001
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1433513:D7D53 RS04660
gene id: 1433513:D7D53_RS04660
uniprot id: A0A387B484
names: Function
names: Similarity
messages: Belongs to the ArsC family.
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1433513:D7D53 RS02060
gene id: 1433513:D7D53_RS02060
uniprot id: A0A387AZ26
names: Similarity
messages: Belongs to the WXG100 family.

1433513:D7D53 RS09885
gene id: 1433513:D7D53_RS09885
uniprot id: A0A387B4P4
names: Similarity
messages: Belongs to the acetyltransferase family.

1433513:D7D53 RS02335
gene id: 1433513:D7D53_RS02335
uniprot id: A0A387AZ63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1433513:D7D53 RS07075
gene id: 1433513:D7D53_RS07075
uniprot id: A0A387BC93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a pheromone, induces cells to develop competence for genetic transformation.
messages: Belongs to the ComC family.
messages: Secreted

1433513:D7D53 RS06500
gene id: 1433513:D7D53_RS06500
uniprot id: A0A387AYD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1433513:D7D53 RS09020
gene id: 1433513:D7D53_RS09020
uniprot id: A0A387B2Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1433513:D7D53 RS00805
gene id: 1433513:D7D53_RS00805
uniprot id: A0A387B8G0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1433513:D7D53 RS02305
gene id: 1433513:D7D53_RS02305
uniprot id: A0A387B0V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1433513:D7D53 RS09225
gene id: 1433513:D7D53_RS09225
uniprot id: A0A387AZK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1433513:D7D53 RS04755
gene id: 1433513:D7D53_RS04755
uniprot id: A0A387B3K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1433513:D7D53 RS03070
gene id: 1433513:D7D53_RS03070
uniprot id: A0A387AZJ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1433513:D7D53 RS08475
gene id: 1433513:D7D53_RS08475
uniprot id: A0A387AZ77
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS09070
gene id: 1433513:D7D53_RS09070
uniprot id: A0A387B2R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1433513:D7D53 RS02490
gene id: 1433513:D7D53_RS02490
uniprot id: A0A387AWJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS04845
gene id: 1433513:D7D53_RS04845
uniprot id: A0A387B0D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1433513:D7D53 RS07755
gene id: 1433513:D7D53_RS07755
uniprot id: A0A387B1S2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1433513:D7D53 RS00185
gene id: 1433513:D7D53_RS00185
uniprot id: A0A387B157
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1433513:D7D53 RS08255
gene id: 1433513:D7D53_RS08255
uniprot id: A0A387B1Y2
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1433513:D7D53 RS07525
gene id: 1433513:D7D53_RS07525
uniprot id: A0A387B3P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS09835
gene id: 1433513:D7D53_RS09835
uniprot id: A0A387B4N5
names: Similarity
messages: Belongs to the UPF0297 family.

1433513:D7D53 RS02870
gene id: 1433513:D7D53_RS02870
uniprot id: A0A387B398
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS04210
gene id: 1433513:D7D53_RS04210
uniprot id: A0A387B081
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1433513:D7D53 RS09935
gene id: 1433513:D7D53_RS09935
uniprot id: A0A387B4Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1433513:D7D53 RS07640
gene id: 1433513:D7D53_RS07640
uniprot id: A0A387AYX3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1433513:D7D53 RS04650
gene id: 1433513:D7D53_RS04650
uniprot id: A0A387AXI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1433513:D7D53 RS04260
gene id: 1433513:D7D53_RS04260
uniprot id: A0A387B090
names: Similarity
messages: Belongs to the agmatine deiminase family.

1433513:D7D53 RS07510
gene id: 1433513:D7D53_RS07510
uniprot id: A0A387B3H7
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily.
messages: Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.

1433513:D7D53 RS07220
gene id: 1433513:D7D53_RS07220
uniprot id: A0A387B3C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1433513:D7D53 RS00365
gene id: 1433513:D7D53_RS00365
uniprot id: A0A387AVP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1433513:D7D53 RS04875
gene id: 1433513:D7D53_RS04875
uniprot id: A0A387B3N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1433513:D7D53 RS06295
gene id: 1433513:D7D53_RS06295
uniprot id: A0A387B2X2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1433513:D7D53 RS00865
gene id: 1433513:D7D53_RS00865
uniprot id: A0A387B0C6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1433513:D7D53 RS05400
gene id: 1433513:D7D53_RS05400
uniprot id: A0A387AXV8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1433513:D7D53 RS02455
gene id: 1433513:D7D53_RS02455
uniprot id: A0A387AZC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1433513:D7D53 RS04880
gene id: 1433513:D7D53_RS04880
uniprot id: A0A387BAZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1433513:D7D53 RS05025
gene id: 1433513:D7D53_RS05025
uniprot id: A0A387B0L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1433513:D7D53 RS03075
gene id: 1433513:D7D53_RS03075
uniprot id: A0A387AWT9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1433513:D7D53 RS05965
gene id: 1433513:D7D53_RS05965
uniprot id: A0A387B487
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1433513:D7D53 RS01605
gene id: 1433513:D7D53_RS01605
uniprot id: A0A387AW58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

1433513:D7D53 RS06360
gene id: 1433513:D7D53_RS06360
uniprot id: A0A387BBQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1433513:D7D53 RS08520
gene id: 1433513:D7D53_RS08520
uniprot id: A0A387B454
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1433513:D7D53 RS00085
gene id: 1433513:D7D53_RS00085
uniprot id: A0A387AVI6
names: Similarity
names: Subunit
messages: Belongs to the UPF0237 family.
messages: Homodimer.

1433513:D7D53 RS00225
gene id: 1433513:D7D53_RS00225
uniprot id: A0A387B1W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

1433513:D7D53 RS09930
gene id: 1433513:D7D53_RS09930
uniprot id: A0A387B349
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1433513:D7D53 RS00040
gene id: 1433513:D7D53_RS00040
uniprot id: A0A387AY31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1433513:D7D53 RS06350
gene id: 1433513:D7D53_RS06350
uniprot id: A0A387B2Y1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1433513:D7D53 RS07875
gene id: 1433513:D7D53_RS07875
uniprot id: A0A387B1U1
names: Similarity
messages: Belongs to the peptidase M29 family.

1433513:D7D53 RS06645
gene id: 1433513:D7D53_RS06645
uniprot id: A0A387B329
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS03500
gene id: 1433513:D7D53_RS03500
uniprot id: A0A387AX11
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS03060
gene id: 1433513:D7D53_RS03060
uniprot id: A0A387B1D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1433513:D7D53 RS05565
gene id: 1433513:D7D53_RS05565
uniprot id: A0A387B402
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1433513:D7D53 RS04275
gene id: 1433513:D7D53_RS04275
uniprot id: A0A387BAL7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS06475
gene id: 1433513:D7D53_RS06475
uniprot id: A0A387B2Z7
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1433513:D7D53 RS02395
gene id: 1433513:D7D53_RS02395
uniprot id: A0A387B299
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1433513:D7D53 RS06340
gene id: 1433513:D7D53_RS06340
uniprot id: A0A387B545
names: Similarity
messages: Belongs to the thioredoxin family.

1433513:D7D53 RS09950
gene id: 1433513:D7D53_RS09950
uniprot id: A0A387B4U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1433513:D7D53 RS09220
gene id: 1433513:D7D53_RS09220
uniprot id: A0A387B2I4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1433513:D7D53 RS08285
gene id: 1433513:D7D53_RS08285
uniprot id: A0A387B3U1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

1433513:D7D53 RS08965
gene id: 1433513:D7D53_RS08965
uniprot id: A0A387BE87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1433513:D7D53 RS07290
gene id: 1433513:D7D53_RS07290
uniprot id: A0A387AYR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1433513:D7D53 RS02710
gene id: 1433513:D7D53_RS02710
uniprot id: A0A387B2G4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1433513:D7D53 RS01665
gene id: 1433513:D7D53_RS01665
uniprot id: A0A387AW66
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1433513:D7D53 RS04410
gene id: 1433513:D7D53_RS04410
uniprot id: A0A387B063
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1433513:D7D53 RS09385
gene id: 1433513:D7D53_RS09385
uniprot id: A0A387AZN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1433513:D7D53 RS02695
gene id: 1433513:D7D53_RS02695
uniprot id: A0A387AWK7
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1433513:D7D53 RS03355
gene id: 1433513:D7D53_RS03355
uniprot id: A0A387AZU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1433513:D7D53 RS00195
gene id: 1433513:D7D53_RS00195
uniprot id: A0A387B818
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1433513:D7D53 RS04860
gene id: 1433513:D7D53_RS04860
uniprot id: A0A387B4C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1433513:D7D53 RS09060
gene id: 1433513:D7D53_RS09060
uniprot id: A0A387B5U2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1433513:D7D53 RS03870
gene id: 1433513:D7D53_RS03870
uniprot id: A0A387B337
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1433513:D7D53 RS09745
gene id: 1433513:D7D53_RS09745
uniprot id: A0A387AZS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1433513:D7D53 RS08210
gene id: 1433513:D7D53_RS08210
uniprot id: A0A387B5C1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1433513:D7D53 RS08120
gene id: 1433513:D7D53_RS08120
uniprot id: A0A387AZ38
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1433513:D7D53 RS07860
gene id: 1433513:D7D53_RS07860
uniprot id: A0A387B3W6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1433513:D7D53 RS04725
gene id: 1433513:D7D53_RS04725
uniprot id: A0A387B3K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1433513:D7D53 RS05135
gene id: 1433513:D7D53_RS05135
uniprot id: A0A387B0N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1433513:D7D53 RS02935
gene id: 1433513:D7D53_RS02935
uniprot id: A0A387AZM7
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS00080
gene id: 1433513:D7D53_RS00080
uniprot id: A0A387AZY2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1433513:D7D53 RS03445
gene id: 1433513:D7D53_RS03445
uniprot id: A0A387AX01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1433513:D7D53 RS02070
gene id: 1433513:D7D53_RS02070
uniprot id: A0A387B241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EssA family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS08890
gene id: 1433513:D7D53_RS08890
uniprot id: A0A387B4B8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1433513:D7D53 RS09470
gene id: 1433513:D7D53_RS09470
uniprot id: A0A387B4L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS09920
gene id: 1433513:D7D53_RS09920
uniprot id: A0A387B6A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1433513:D7D53 RS01640
gene id: 1433513:D7D53_RS01640
uniprot id: A0A387B1W0
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS03080
gene id: 1433513:D7D53_RS03080
uniprot id: A0A387B2P2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1433513:D7D53 RS09840
gene id: 1433513:D7D53_RS09840
uniprot id: A0A387B6D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1433513:D7D53 RS01920
gene id: 1433513:D7D53_RS01920
uniprot id: A0A387B946
names: Similarity
messages: Belongs to the TPP enzyme family.

1433513:D7D53 RS01975
gene id: 1433513:D7D53_RS01975
uniprot id: A0A387B957
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1433513:D7D53 RS04585
gene id: 1433513:D7D53_RS04585
uniprot id: A0A387AXH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1433513:D7D53 RS06975
gene id: 1433513:D7D53_RS06975
uniprot id: A0A387AYL2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1433513:D7D53 RS09495
gene id: 1433513:D7D53_RS09495
uniprot id: A0A387B6H3
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1433513:D7D53 RS07130
gene id: 1433513:D7D53_RS07130
uniprot id: A0A387B3J2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1433513:D7D53 RS07785
gene id: 1433513:D7D53_RS07785
uniprot id: A0A387B3N0
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1433513:D7D53 RS00045
gene id: 1433513:D7D53_RS00045
uniprot id: A0A387AVJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1433513:D7D53 RS09200
gene id: 1433513:D7D53_RS09200
uniprot id: A0A387BDC4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1433513:D7D53 RS01195
gene id: 1433513:D7D53_RS01195
uniprot id: A0A387AVY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1433513:D7D53 RS02660
gene id: 1433513:D7D53_RS02660
uniprot id: A0A387B356
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1433513:D7D53 RS07475
gene id: 1433513:D7D53_RS07475
uniprot id: A0A387AYU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1433513:D7D53 RS09900
gene id: 1433513:D7D53_RS09900
uniprot id: A0A387B4T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1433513:D7D53 RS09635
gene id: 1433513:D7D53_RS09635
uniprot id: A0A387AZQ9
names: Similarity
messages: Belongs to the UPF0177 family.

1433513:D7D53 RS04655
gene id: 1433513:D7D53_RS04655
uniprot id: A0A387B3I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

1433513:D7D53 RS05785
gene id: 1433513:D7D53_RS05785
uniprot id: A0A387AY12
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1433513:D7D53 RS01540
gene id: 1433513:D7D53_RS01540
uniprot id: A0A387AYT8
names: Similarity
messages: Belongs to the Dps family.

1433513:D7D53 RS09605
gene id: 1433513:D7D53_RS09605
uniprot id: A0A387B6I6
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1433513:D7D53 RS00050
gene id: 1433513:D7D53_RS00050
uniprot id: A0A387B107
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1433513:D7D53 RS01905
gene id: 1433513:D7D53_RS01905
uniprot id: A0A387AZ34
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1433513:D7D53 RS08825
gene id: 1433513:D7D53_RS08825
uniprot id: A0A387B5N2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1433513:D7D53 RS03730
gene id: 1433513:D7D53_RS03730
uniprot id: A0A387B007
names: Subcellular Location Annotation
messages: Membrane

1433513:D7D53 RS01530
gene id: 1433513:D7D53_RS01530
uniprot id: A0A387AW36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1433513:D7D53 RS08810
gene id: 1433513:D7D53_RS08810
uniprot id: A0A387B679
names: Similarity
messages: Belongs to the acetyltransferase family.

1433513:D7D53 RS07650
gene id: 1433513:D7D53_RS07650
uniprot id: A0A387AYX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1433513:D7D53 RS09240
gene id: 1433513:D7D53_RS09240
uniprot id: A0A387B2U3
names: Similarity
messages: Belongs to the IMPACT family.

1433513:D7D53 RS07830
gene id: 1433513:D7D53_RS07830
uniprot id: A0A387B5U1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1433513:D7D53 RS02310
gene id: 1433513:D7D53_RS02310
uniprot id: A0A387B275
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1433513:D7D53 RS07520
gene id: 1433513:D7D53_RS07520
uniprot id: A0A387BCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1433513:D7D53 RS01995
gene id: 1433513:D7D53_RS01995
uniprot id: A0A387AZ19
names: Similarity
messages: Belongs to the leucine-binding protein family.

1433513:D7D53 RS01215
gene id: 1433513:D7D53_RS01215
uniprot id: A0A387B2F8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.