1432656:X802 RS04115
gene id: 1432656:X802_RS04115
uniprot id: A0A0X1KJQ6
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS04950
gene id: 1432656:X802_RS04950
uniprot id: A0A0X1KK32
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1432656:X802 RS07970
gene id: 1432656:X802_RS07970
uniprot id: A0A0X1KLL2
names: Subcellular Location Annotation
messages: Cytoplasm

1432656:X802 RS06650
gene id: 1432656:X802_RS06650
uniprot id: A0A0X1KKY5
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS07595
gene id: 1432656:X802_RS07595
uniprot id: A0A0X1KLE5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1432656:X802 RS00395
gene id: 1432656:X802_RS00395
uniprot id: A0A0X1KHT3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1432656:X802 RS02665
gene id: 1432656:X802_RS02665
uniprot id: A0A0X1KIY4
names: Similarity
messages: Belongs to the enolase family.

1432656:X802 RS07790
gene id: 1432656:X802_RS07790
uniprot id: A0A0X1KLG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1432656:X802 RS01315
gene id: 1432656:X802_RS01315
uniprot id: A0A0X1KIA3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

1432656:X802 RS08600
gene id: 1432656:X802_RS08600
uniprot id: A0A0X1KLU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

1432656:X802 RS03620
gene id: 1432656:X802_RS03620
uniprot id: A0A0X1KJB8
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1432656:X802 RS01245
gene id: 1432656:X802_RS01245
uniprot id: A0A0X1KI82
names: Similarity
messages: Belongs to the UPF0166 family.

1432656:X802 RS06345
gene id: 1432656:X802_RS06345
uniprot id: A0A0X1KKR9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

1432656:X802 RS10545
gene id: 1432656:X802_RS10545
uniprot id: A0A0X1KMW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1432656:X802 RS01810
gene id: 1432656:X802_RS01810
uniprot id: A0A0X1KIJ0
names: Similarity
messages: Belongs to the AOR/FOR family.

1432656:X802 RS00130
gene id: 1432656:X802_RS00130
uniprot id: A0A0X1KHP4
names: Similarity
messages: Belongs to the GbsR family.

1432656:X802 RS03775
gene id: 1432656:X802_RS03775
uniprot id: A0A0X1KJF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1432656:X802 RS01545
gene id: 1432656:X802_RS01545
uniprot id: A0A0X1KID7
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

1432656:X802 RS06095
gene id: 1432656:X802_RS06095
uniprot id: A0A0X1KKN0
names: Similarity
messages: Belongs to the RutC family.

1432656:X802 RS01575
gene id: 1432656:X802_RS01575
uniprot id: A0A0X1KIF5
names: Similarity
messages: Belongs to the HerA family.

1432656:X802 RS09730
gene id: 1432656:X802_RS09730
uniprot id: A0A0X1KMH1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS05060
gene id: 1432656:X802_RS05060
uniprot id: A0A0X1KK79
names: Similarity
messages: Belongs to the threonine synthase family.

1432656:X802 RS02680
gene id: 1432656:X802_RS02680
uniprot id: A0A0X1KIZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1432656:X802 RS04485
gene id: 1432656:X802_RS04485
uniprot id: A0A0X1KJV3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS02880
gene id: 1432656:X802_RS02880
uniprot id: A0A0X1KJ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

1432656:X802 RS08845
gene id: 1432656:X802_RS08845
uniprot id: A0A0X1KM24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

1432656:X802 RS09605
gene id: 1432656:X802_RS09605
uniprot id: A0A0X1KME3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

1432656:X802 RS10005
gene id: 1432656:X802_RS10005
uniprot id: A0A0X1KML0
names: Similarity
messages: Belongs to the peptidase U62 family.

1432656:X802 RS01585
gene id: 1432656:X802_RS01585
uniprot id: A0A0X1KIE6
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS00570
gene id: 1432656:X802_RS00570
uniprot id: A0A0X1KHW7
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1432656:X802 RS10340
gene id: 1432656:X802_RS10340
uniprot id: A0A0X1KMU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1432656:X802 RS03635
gene id: 1432656:X802_RS03635
uniprot id: A0A0X1KJH5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Potential transporter for phosphate.

1432656:X802 RS05460
gene id: 1432656:X802_RS05460
uniprot id: A0A0X1KKD9
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1432656:X802 RS06300
gene id: 1432656:X802_RS06300
uniprot id: A0A0X1KKQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

1432656:X802 RS04215
gene id: 1432656:X802_RS04215
uniprot id: A0A0X1KJS8
names: Similarity
messages: Belongs to the UPF0252 family.

1432656:X802 RS08500
gene id: 1432656:X802_RS08500
uniprot id: A0A0X1KNF5
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS06620
gene id: 1432656:X802_RS06620
uniprot id: A0A0X1KKU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

1432656:X802 RS03625
gene id: 1432656:X802_RS03625
uniprot id: A0A0X1KJF7
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1432656:X802 RS07335
gene id: 1432656:X802_RS07335
uniprot id: A0A0X1KL95
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1432656:X802 RS06895
gene id: 1432656:X802_RS06895
uniprot id: A0A0X1KL00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1432656:X802 RS03725
gene id: 1432656:X802_RS03725
uniprot id: A0A0X1KJE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS08755
gene id: 1432656:X802_RS08755
uniprot id: A0A0X1KLW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1432656:X802 RS01715
gene id: 1432656:X802_RS01715
uniprot id: A0A0X1KIH6
names: Similarity
messages: Belongs to the UPF0292 family.

1432656:X802 RS06025
gene id: 1432656:X802_RS06025
uniprot id: A0A0X1KKK6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1432656:X802 RS05105
gene id: 1432656:X802_RS05105
uniprot id: A0A0X1KK48
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS08520
gene id: 1432656:X802_RS08520
uniprot id: A0A0X1KLW8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS08060
gene id: 1432656:X802_RS08060
uniprot id: A0A0X1KLM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

1432656:X802 RS00690
gene id: 1432656:X802_RS00690
uniprot id: A0A0X1KN06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1432656:X802 RS09610
gene id: 1432656:X802_RS09610
uniprot id: A0A0X1KMF8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1432656:X802 RS10445
gene id: 1432656:X802_RS10445
uniprot id: A0A0X1KMU8
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS07395
gene id: 1432656:X802_RS07395
uniprot id: A0A0X1KLD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1432656:X802 RS09305
gene id: 1432656:X802_RS09305
uniprot id: A0A0X1KM85
names: Caution
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS03465
gene id: 1432656:X802_RS03465
uniprot id: A0A0X1KJB5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS03760
gene id: 1432656:X802_RS03760
uniprot id: A0A0X1KJH2
names: Similarity
messages: Belongs to the peptidase U62 family.

1432656:X802 RS10080
gene id: 1432656:X802_RS10080
uniprot id: A0A0X1KMP6
names: Similarity
messages: Belongs to the UPF0045 family.

1432656:X802 RS02640
gene id: 1432656:X802_RS02640
uniprot id: A0A0X1KIW7
names: Similarity
messages: Belongs to the FUN14 family.

1432656:X802 RS05160
gene id: 1432656:X802_RS05160
uniprot id: A0A0X1KK60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1432656:X802 RS03730
gene id: 1432656:X802_RS03730
uniprot id: A0A0X1KJH7
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS06960
gene id: 1432656:X802_RS06960
uniprot id: A0A0X1KL13
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS02480
gene id: 1432656:X802_RS02480
uniprot id: A0A0X1KIT5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1432656:X802 RS01675
gene id: 1432656:X802_RS01675
uniprot id: A0A0X1KIF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1432656:X802 RS04505
gene id: 1432656:X802_RS04505
uniprot id: A0A0X1KJW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1432656:X802 RS04605
gene id: 1432656:X802_RS04605
uniprot id: A0A0X1KN47
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1432656:X802 RS00430
gene id: 1432656:X802_RS00430
uniprot id: A0A0X1KHV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1432656:X802 RS02160
gene id: 1432656:X802_RS02160
uniprot id: A0A0X1KIP3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1432656:X802 RS09245
gene id: 1432656:X802_RS09245
uniprot id: A0A0X1KM71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1432656:X802 RS06265
gene id: 1432656:X802_RS06265
uniprot id: A0A0X1KKR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

1432656:X802 RS03685
gene id: 1432656:X802_RS03685
uniprot id: A0A0X1KJE4
names: Similarity
messages: Belongs to the UPF0273 family.

1432656:X802 RS04720
gene id: 1432656:X802_RS04720
uniprot id: A0A0X1KJY1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1432656:X802 RS06455
gene id: 1432656:X802_RS06455
uniprot id: A0A0X1KND5
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1432656:X802 RS04725
gene id: 1432656:X802_RS04725
uniprot id: A0A0X1KK02
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1432656:X802 RS03015
gene id: 1432656:X802_RS03015
uniprot id: A0A0X1KJ37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1432656:X802 RS06950
gene id: 1432656:X802_RS06950
uniprot id: A0A0X1KL10
names: Similarity
messages: Belongs to the peptidase M20A family.

1432656:X802 RS01730
gene id: 1432656:X802_RS01730
uniprot id: A0A0X1KIG9
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1432656:X802 RS04925
gene id: 1432656:X802_RS04925
uniprot id: A0A0X1KK24
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1432656:X802 RS07550
gene id: 1432656:X802_RS07550
uniprot id: A0A0X1KLC6
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1432656:X802 RS05510
gene id: 1432656:X802_RS05510
uniprot id: A0A0X1KKC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

1432656:X802 RS03555
gene id: 1432656:X802_RS03555
uniprot id: A0A0X1KJD2
names: Similarity
messages: Belongs to the HupF/HypC family.

1432656:X802 RS06135
gene id: 1432656:X802_RS06135
uniprot id: A0A0X1KKR0
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS03925
gene id: 1432656:X802_RS03925
uniprot id: A0A0X1KJL0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1432656:X802 RS02250
gene id: 1432656:X802_RS02250
uniprot id: A0A0X1KIR4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1432656:X802 RS00560
gene id: 1432656:X802_RS00560
uniprot id: A0A0X1KHW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

1432656:X802 RS06890
gene id: 1432656:X802_RS06890
uniprot id: A0A0X1KL38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1432656:X802 RS05725
gene id: 1432656:X802_RS05725
uniprot id: A0A0X1KKI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

1432656:X802 RS06390
gene id: 1432656:X802_RS06390
uniprot id: A0A0X1KKT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1432656:X802 RS01890
gene id: 1432656:X802_RS01890
uniprot id: A0A0X1KIK0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS02345
gene id: 1432656:X802_RS02345
uniprot id: A0A0X1KIV3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1432656:X802 RS01420
gene id: 1432656:X802_RS01420
uniprot id: A0A0X1KIC8
names: Similarity
messages: Belongs to the P(II) protein family.

1432656:X802 RS03855
gene id: 1432656:X802_RS03855
uniprot id: A0A0X1KJH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

1432656:X802 RS06645
gene id: 1432656:X802_RS06645
uniprot id: A0A0X1KKX1
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

1432656:X802 RS10085
gene id: 1432656:X802_RS10085
uniprot id: A0A0X1KMN0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1432656:X802 RS08325
gene id: 1432656:X802_RS08325
uniprot id: A0A0X1KLR1
names: Similarity
messages: Belongs to the HypE family.

1432656:X802 RS08975
gene id: 1432656:X802_RS08975
uniprot id: A0A0X1KM17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1432656:X802 RS05250
gene id: 1432656:X802_RS05250
uniprot id: A0A0X1KKA2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1432656:X802 RS05150
gene id: 1432656:X802_RS05150
uniprot id: A0A0X1KK87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homotetramer; although the tetramer contains four active sites, only two participate in the cleavage. Therefore, it should be considered as a dimer of dimers.

1432656:X802 RS09440
gene id: 1432656:X802_RS09440
uniprot id: A0A0X1KMB5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1432656:X802 RS01140
gene id: 1432656:X802_RS01140
uniprot id: A0A0X1KI55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1432656:X802 RS04065
gene id: 1432656:X802_RS04065
uniprot id: A0A0X1KJP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1432656:X802 RS08650
gene id: 1432656:X802_RS08650
uniprot id: A0A0X1KLU9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1432656:X802 RS04270
gene id: 1432656:X802_RS04270
uniprot id: A0A0X1KJQ0
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

1432656:X802 RS03640
gene id: 1432656:X802_RS03640
uniprot id: A0A0X1KJE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1432656:X802 RS01215
gene id: 1432656:X802_RS01215
uniprot id: A0A0X1KI68
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS09920
gene id: 1432656:X802_RS09920
uniprot id: A0A0X1KMK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1432656:X802 RS09125
gene id: 1432656:X802_RS09125
uniprot id: A0A0X1KM52
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS02190
gene id: 1432656:X802_RS02190
uniprot id: A0A0X1KIP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1432656:X802 RS04670
gene id: 1432656:X802_RS04670
uniprot id: A0A0X1KJX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1432656:X802 RS03000
gene id: 1432656:X802_RS03000
uniprot id: A0A0X1KJ53
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1432656:X802 RS01785
gene id: 1432656:X802_RS01785
uniprot id: A0A0X1KIH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

1432656:X802 RS02910
gene id: 1432656:X802_RS02910
uniprot id: A0A0X1KJ44
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1432656:X802 RS02340
gene id: 1432656:X802_RS02340
uniprot id: A0A0X1KIR7
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS05455
gene id: 1432656:X802_RS05455
uniprot id: A0A0X1KKB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS01770
gene id: 1432656:X802_RS01770
uniprot id: A0A0X1KII6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

1432656:X802 RS08775
gene id: 1432656:X802_RS08775
uniprot id: A0A0X1KM01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

1432656:X802 RS08790
gene id: 1432656:X802_RS08790
uniprot id: A0A0X1KLZ0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1432656:X802 RS07690
gene id: 1432656:X802_RS07690
uniprot id: A0A0X1KLI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Binds 2 Mg(2+) or Mn(2+) ions per subunit.
messages: Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
messages: Cell membrane

1432656:X802 RS10470
gene id: 1432656:X802_RS10470
uniprot id: A0A0X1KMV7
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1432656:X802 RS00050
gene id: 1432656:X802_RS00050
uniprot id: A0A0X1KHM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1432656:X802 RS08030
gene id: 1432656:X802_RS08030
uniprot id: A0A0X1KLL4
names: Similarity
messages: Belongs to the UPF0201 family.

1432656:X802 RS09660
gene id: 1432656:X802_RS09660
uniprot id: A0A0X1KMG7
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS07515
gene id: 1432656:X802_RS07515
uniprot id: A0A0X1KLD7
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

1432656:X802 RS08770
gene id: 1432656:X802_RS08770
uniprot id: A0A0X1KLY5
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

1432656:X802 RS09380
gene id: 1432656:X802_RS09380
uniprot id: A0A0X1KMA4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1432656:X802 RS05205
gene id: 1432656:X802_RS05205
uniprot id: A0A0X1KK99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

1432656:X802 RS04200
gene id: 1432656:X802_RS04200
uniprot id: A0A0X1KJN8
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS01190
gene id: 1432656:X802_RS01190
uniprot id: A0A0X1KI72
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS08470
gene id: 1432656:X802_RS08470
uniprot id: A0A0X1KLR7
names: Similarity
messages: Belongs to the UPF0107 family.

1432656:X802 RS09710
gene id: 1432656:X802_RS09710
uniprot id: A0A0X1KMH7
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

1432656:X802 RS01380
gene id: 1432656:X802_RS01380
uniprot id: A0A0X1KI97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1432656:X802 RS02500
gene id: 1432656:X802_RS02500
uniprot id: A0A0X1KIV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1432656:X802 RS07865
gene id: 1432656:X802_RS07865
uniprot id: A0A0X1KLJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1432656:X802 RS06200
gene id: 1432656:X802_RS06200
uniprot id: A0A0X1KKM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1432656:X802 RS00590
gene id: 1432656:X802_RS00590
uniprot id: A0A0X1KHY9
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

1432656:X802 RS01285
gene id: 1432656:X802_RS01285
uniprot id: A0A0X1KI76
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1432656:X802 RS01625
gene id: 1432656:X802_RS01625
uniprot id: A0A0X1KII1
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS10285
gene id: 1432656:X802_RS10285
uniprot id: A0A0X1KMU6
names: Similarity
messages: Belongs to the UPF0127 family.

1432656:X802 RS09875
gene id: 1432656:X802_RS09875
uniprot id: A0A0X1KMJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1432656:X802 RS07750
gene id: 1432656:X802_RS07750
uniprot id: A0A0X1KNB3
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS09955
gene id: 1432656:X802_RS09955
uniprot id: A0A0X1KML1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1432656:X802 RS04615
gene id: 1432656:X802_RS04615
uniprot id: A0A0X1KJW6
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

1432656:X802 RS02610
gene id: 1432656:X802_RS02610
uniprot id: A0A0X1KIX9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

1432656:X802 RS10290
gene id: 1432656:X802_RS10290
uniprot id: A0A0X1KMT2
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1432656:X802 RS09665
gene id: 1432656:X802_RS09665
uniprot id: A0A0X1KME0
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS02150
gene id: 1432656:X802_RS02150
uniprot id: A0A0X1KIN5
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS03935
gene id: 1432656:X802_RS03935
uniprot id: A0A0X1KJK5
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS00345
gene id: 1432656:X802_RS00345
uniprot id: A0A0X1KHS6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS07695
gene id: 1432656:X802_RS07695
uniprot id: A0A0X1KLE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

1432656:X802 RS07045
gene id: 1432656:X802_RS07045
uniprot id: A0A0X1KL68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1432656:X802 RS08925
gene id: 1432656:X802_RS08925
uniprot id: A0A0X1KM10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Forms a Heterooligomeric complex of two stacked eight-membered rings.
messages: Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.

1432656:X802 RS01325
gene id: 1432656:X802_RS01325
uniprot id: A0A0X1KIB5
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS08840
gene id: 1432656:X802_RS08840
uniprot id: A0A0X1KM02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1432656:X802 RS10430
gene id: 1432656:X802_RS10430
uniprot id: A0A0X1KMR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

1432656:X802 RS06670
gene id: 1432656:X802_RS06670
uniprot id: A0A0X1KKV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS10065
gene id: 1432656:X802_RS10065
uniprot id: A0A0X1KMM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1432656:X802 RS05285
gene id: 1432656:X802_RS05285
uniprot id: A0A0X1KK96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1432656:X802 RS06850
gene id: 1432656:X802_RS06850
uniprot id: A0A0X1KL04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1432656:X802 RS03735
gene id: 1432656:X802_RS03735
uniprot id: A0A0X1KJF4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs.

1432656:X802 RS07725
gene id: 1432656:X802_RS07725
uniprot id: A0A0X1KLH5
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS07890
gene id: 1432656:X802_RS07890
uniprot id: A0A0X1KLI1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

1432656:X802 RS09845
gene id: 1432656:X802_RS09845
uniprot id: A0A0X1KMI4
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1432656:X802 RS09975
gene id: 1432656:X802_RS09975
uniprot id: A0A0X1KML3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1432656:X802 RS10375
gene id: 1432656:X802_RS10375
uniprot id: A0A0X1KMT7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS03805
gene id: 1432656:X802_RS03805
uniprot id: A0A0X1KJJ0
names: Similarity
messages: Belongs to the UPF0175 family.

1432656:X802 RS06740
gene id: 1432656:X802_RS06740
uniprot id: A0A0X1KL16
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1432656:X802 RS08565
gene id: 1432656:X802_RS08565
uniprot id: A0A0X1KLU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

1432656:X802 RS04875
gene id: 1432656:X802_RS04875
uniprot id: A0A0X1KK37
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1432656:X802 RS02660
gene id: 1432656:X802_RS02660
uniprot id: A0A0X1KIV7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1432656:X802 RS06840
gene id: 1432656:X802_RS06840
uniprot id: A0A0X1KL28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

1432656:X802 RS08690
gene id: 1432656:X802_RS08690
uniprot id: A0A0X1KLW9
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS07175
gene id: 1432656:X802_RS07175
uniprot id: A0A0X1KL49
names: Similarity
messages: Belongs to the UPF0251 family.

1432656:X802 RS04140
gene id: 1432656:X802_RS04140
uniprot id: A0A0X1KJQ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS02690
gene id: 1432656:X802_RS02690
uniprot id: A0A0X1KIW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1432656:X802 RS06760
gene id: 1432656:X802_RS06760
uniprot id: A0A0X1KL07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

1432656:X802 RS10145
gene id: 1432656:X802_RS10145
uniprot id: A0A0X1KMN9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1432656:X802 RS03965
gene id: 1432656:X802_RS03965
uniprot id: A0A0X1KJJ1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1432656:X802 RS03815
gene id: 1432656:X802_RS03815
uniprot id: A0A0X1KJK2
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

1432656:X802 RS08645
gene id: 1432656:X802_RS08645
uniprot id: A0A0X1KLY4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1432656:X802 RS04970
gene id: 1432656:X802_RS04970
uniprot id: A0A0X1KK57
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

1432656:X802 RS07710
gene id: 1432656:X802_RS07710
uniprot id: A0A0X1KLG9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1432656:X802 RS10265
gene id: 1432656:X802_RS10265
uniprot id: A0A0X1KMQ1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1432656:X802 RS00205
gene id: 1432656:X802_RS00205
uniprot id: A0A0X1KHP9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1432656:X802 RS06130
gene id: 1432656:X802_RS06130
uniprot id: A0A0X1KKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

1432656:X802 RS03660
gene id: 1432656:X802_RS03660
uniprot id: A0A0X1KJF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1432656:X802 RS10515
gene id: 1432656:X802_RS10515
uniprot id: A0A0X1KMV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

1432656:X802 RS09500
gene id: 1432656:X802_RS09500
uniprot id: A0A0X1KMC3
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1432656:X802 RS06865
gene id: 1432656:X802_RS06865
uniprot id: A0A0X1KL11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1432656:X802 RS03850
gene id: 1432656:X802_RS03850
uniprot id: A0A0X1KJK8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

1432656:X802 RS07660
gene id: 1432656:X802_RS07660
uniprot id: A0A0X1KLF2
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1432656:X802 RS00150
gene id: 1432656:X802_RS00150
uniprot id: A0A0X1KHP3
names: Similarity
messages: Belongs to the UPF0045 family.

1432656:X802 RS02115
gene id: 1432656:X802_RS02115
uniprot id: A0A0X1KIR3
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.
messages: Belongs to the SIS family. PHI subfamily.

1432656:X802 RS09670
gene id: 1432656:X802_RS09670
uniprot id: A0A0X1KME9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1432656:X802 RS07820
gene id: 1432656:X802_RS07820
uniprot id: A0A0X1KLI3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1432656:X802 RS03020
gene id: 1432656:X802_RS03020
uniprot id: A0A0X1KJ11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

1432656:X802 RS00535
gene id: 1432656:X802_RS00535
uniprot id: A0A0X1KHY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1432656:X802 RS03405
gene id: 1432656:X802_RS03405
uniprot id: A0A0X1KJA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1432656:X802 RS08350
gene id: 1432656:X802_RS08350
uniprot id: A0A0X1KLP8
names: Similarity
messages: Belongs to the IMPACT family.

1432656:X802 RS10115
gene id: 1432656:X802_RS10115
uniprot id: A0A0X1KMN2
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1432656:X802 RS06195
gene id: 1432656:X802_RS06195
uniprot id: A0A0X1KKS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1432656:X802 RS05230
gene id: 1432656:X802_RS05230
uniprot id: A0A0X1KK74
names: Similarity
messages: Belongs to the class-I fumarase family.

1432656:X802 RS00380
gene id: 1432656:X802_RS00380
uniprot id: A0A0X1KHU4
names: Function
names: Similarity
messages: Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
messages: Belongs to the archease family.

1432656:X802 RS07720
gene id: 1432656:X802_RS07720
uniprot id: A0A0X1KLH7
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS03560
gene id: 1432656:X802_RS03560
uniprot id: A0A0X1KJE8
names: Similarity
messages: Belongs to the HypD family.

1432656:X802 RS04230
gene id: 1432656:X802_RS04230
uniprot id: A0A0X1KJS6
names: Subunit
messages: Homotetramer.

1432656:X802 RS08710
gene id: 1432656:X802_RS08710
uniprot id: A0A0X1KLX0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1432656:X802 RS01765
gene id: 1432656:X802_RS01765
uniprot id: A0A0X1KII0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1432656:X802 RS03310
gene id: 1432656:X802_RS03310
uniprot id: A0A0X1KJ71
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS03915
gene id: 1432656:X802_RS03915
uniprot id: A0A0X1KJI8
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

1432656:X802 RS02695
gene id: 1432656:X802_RS02695
uniprot id: A0A0X1KJ07
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

1432656:X802 RS06290
gene id: 1432656:X802_RS06290
uniprot id: A0A0X1KKS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

1432656:X802 RS10540
gene id: 1432656:X802_RS10540
uniprot id: A0A0X1KMV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1432656:X802 RS01495
gene id: 1432656:X802_RS01495
uniprot id: A0A0X1KIC9
names: Similarity
messages: Belongs to the MEMO1 family.

1432656:X802 RS00330
gene id: 1432656:X802_RS00330
uniprot id: A0A0X1KHT4
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS09695
gene id: 1432656:X802_RS09695
uniprot id: A0A0X1KMG0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1432656:X802 RS08980
gene id: 1432656:X802_RS08980
uniprot id: A0A0X1KM19
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS08665
gene id: 1432656:X802_RS08665
uniprot id: A0A0X1KLW4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1432656:X802 RS04305
gene id: 1432656:X802_RS04305
uniprot id: A0A0X1KJS4
names: Similarity
messages: Belongs to the AOR/FOR family.

1432656:X802 RS08630
gene id: 1432656:X802_RS08630
uniprot id: A0A0X1KLV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1432656:X802 RS01485
gene id: 1432656:X802_RS01485
uniprot id: A0A0X1KID0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Cytoplasm

1432656:X802 RS06190
gene id: 1432656:X802_RS06190
uniprot id: A0A0X1KKN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

1432656:X802 RS08525
gene id: 1432656:X802_RS08525
uniprot id: A0A0X1KLU6
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

1432656:X802 RS06485
gene id: 1432656:X802_RS06485
uniprot id: A0A0X1KKS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

1432656:X802 RS00490
gene id: 1432656:X802_RS00490
uniprot id: A0A0X1KHX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1432656:X802 RS00055
gene id: 1432656:X802_RS00055
uniprot id: A0A0X1KHM8
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS02895
gene id: 1432656:X802_RS02895
uniprot id: A0A0X1KIZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal adenylate kinase family.
messages: Cytoplasm

1432656:X802 RS00625
gene id: 1432656:X802_RS00625
uniprot id: A0A0X1KHY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1432656:X802 RS01410
gene id: 1432656:X802_RS01410
uniprot id: A0A0X1KIC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1432656:X802 RS06120
gene id: 1432656:X802_RS06120
uniprot id: A0A0X1KKP5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1432656:X802 RS02520
gene id: 1432656:X802_RS02520
uniprot id: A0A0X1KIT6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1432656:X802 RS07645
gene id: 1432656:X802_RS07645
uniprot id: A0A0X1KLD8
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

1432656:X802 RS02325
gene id: 1432656:X802_RS02325
uniprot id: A0A0X1KIS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1432656:X802 RS09140
gene id: 1432656:X802_RS09140
uniprot id: A0A0X1KM73
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-65 and Arg-68) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

1432656:X802 RS09510
gene id: 1432656:X802_RS09510
uniprot id: A0A0X1KMA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1432656:X802 RS02825
gene id: 1432656:X802_RS02825
uniprot id: A0A0X1KJ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1432656:X802 RS08655
gene id: 1432656:X802_RS08655
uniprot id: A0A0X1KLW1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1432656:X802 RS00025
gene id: 1432656:X802_RS00025
uniprot id: A0A0X1KHM3
names: Subunit
messages: Homodimer.

1432656:X802 RS02920
gene id: 1432656:X802_RS02920
uniprot id: A0A0X1KIZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1432656:X802 RS10060
gene id: 1432656:X802_RS10060
uniprot id: A0A0X1KML4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1432656:X802 RS05540
gene id: 1432656:X802_RS05540
uniprot id: A0A0X1KKG0
names: Similarity
messages: Belongs to the UPF0282 family.

1432656:X802 RS05935
gene id: 1432656:X802_RS05935
uniprot id: A0A0X1KKJ1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1432656:X802 RS04580
gene id: 1432656:X802_RS04580
uniprot id: A0A0X1KJZ1
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

1432656:X802 RS01720
gene id: 1432656:X802_RS01720
uniprot id: A0A0X1KIG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

1432656:X802 RS10525
gene id: 1432656:X802_RS10525
uniprot id: A0A0X1KMV6
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1432656:X802 RS06990
gene id: 1432656:X802_RS06990
uniprot id: A0A0X1KL26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1432656:X802 RS04915
gene id: 1432656:X802_RS04915
uniprot id: A0A0X1KK34
names: Similarity
messages: Belongs to the BtpA family.

1432656:X802 RS07610
gene id: 1432656:X802_RS07610
uniprot id: A0A0X1KLE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1432656:X802 RS07985
gene id: 1432656:X802_RS07985
uniprot id: A0A0X1KLN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1432656:X802 RS05965
gene id: 1432656:X802_RS05965
uniprot id: A0A0X1KKJ5
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1432656:X802 RS06985
gene id: 1432656:X802_RS06985
uniprot id: A0A0X1KL30
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1432656:X802 RS06260
gene id: 1432656:X802_RS06260
uniprot id: A0A0X1KKN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

1432656:X802 RS06165
gene id: 1432656:X802_RS06165
uniprot id: A0A0X1KKM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

1432656:X802 RS02845
gene id: 1432656:X802_RS02845
uniprot id: A0A0X1KIY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1432656:X802 RS02885
gene id: 1432656:X802_RS02885
uniprot id: A0A0X1KJ20
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

1432656:X802 RS04335
gene id: 1432656:X802_RS04335
uniprot id: A0A0X1KJR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

1432656:X802 RS07855
gene id: 1432656:X802_RS07855
uniprot id: A0A0X1KLI9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

1432656:X802 RS05675
gene id: 1432656:X802_RS05675
uniprot id: A0A0X1KKF5
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS00270
gene id: 1432656:X802_RS00270
uniprot id: A0A0X1KHR5
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

1432656:X802 RS00555
gene id: 1432656:X802_RS00555
uniprot id: A0A0X1KHW9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1432656:X802 RS07870
gene id: 1432656:X802_RS07870
uniprot id: A0A0X1KLJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS04535
gene id: 1432656:X802_RS04535
uniprot id: A0A0X1KJW4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

1432656:X802 RS05755
gene id: 1432656:X802_RS05755
uniprot id: A0A0X1KKF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1432656:X802 RS01635
gene id: 1432656:X802_RS01635
uniprot id: A0A0X1KIF0
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

1432656:X802 RS01185
gene id: 1432656:X802_RS01185
uniprot id: A0A0X1KI71
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS01150
gene id: 1432656:X802_RS01150
uniprot id: A0A0X1KI58
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the archaeal N-glycosylase/DNA lyase (AGOG) family.
messages: Contains two alpha-helical subdomains, with the 8-oxoguanine binding site located in a cleft at their interface. Contains a helix-hairpin-helix (HhH) structural motif and a Gly/Pro-rich sequence followed by a conserved Asp (HhH-GPD motif).
messages: DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS08675
gene id: 1432656:X802_RS08675
uniprot id: A0A0X1KLX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1432656:X802 RS09585
gene id: 1432656:X802_RS09585
uniprot id: A0A0X1KMF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1432656:X802 RS01550
gene id: 1432656:X802_RS01550
uniprot id: A0A0X1KIE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

1432656:X802 RS10325
gene id: 1432656:X802_RS10325
uniprot id: A0A0X1KMS7
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1432656:X802 RS02015
gene id: 1432656:X802_RS02015
uniprot id: A0A0X1KIM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1432656:X802 RS06365
gene id: 1432656:X802_RS06365
uniprot id: A0A0X1KKT1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1432656:X802 RS01075
gene id: 1432656:X802_RS01075
uniprot id: A0A0X1KI38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1432656:X802 RS02755
gene id: 1432656:X802_RS02755
uniprot id: A0A0X1KIZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1432656:X802 RS03370
gene id: 1432656:X802_RS03370
uniprot id: A0A0X1KJ81
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS08785
gene id: 1432656:X802_RS08785
uniprot id: A0A0X1KLZ9
names: Similarity
messages: Belongs to the peptidase S8 family.

1432656:X802 RS01440
gene id: 1432656:X802_RS01440
uniprot id: A0A0X1KIB8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

1432656:X802 RS05380
gene id: 1432656:X802_RS05380
uniprot id: A0A0X1KKC9
names: Similarity
messages: Belongs to the UPF0215 family.

1432656:X802 RS04860
gene id: 1432656:X802_RS04860
uniprot id: A0A0X1KK03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1432656:X802 RS07910
gene id: 1432656:X802_RS07910
uniprot id: A0A0X1KLM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1432656:X802 RS00845
gene id: 1432656:X802_RS00845
uniprot id: A0A0X1KI05
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

1432656:X802 RS00185
gene id: 1432656:X802_RS00185
uniprot id: A0A0X1KHQ4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1432656:X802 RS07990
gene id: 1432656:X802_RS07990
uniprot id: A0A0X1KLJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1432656:X802 RS06845
gene id: 1432656:X802_RS06845
uniprot id: A0A0X1KKZ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS01425
gene id: 1432656:X802_RS01425
uniprot id: A0A0X1KIA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1432656:X802 RS04190
gene id: 1432656:X802_RS04190
uniprot id: A0A0X1KJR9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1432656:X802 RS05880
gene id: 1432656:X802_RS05880
uniprot id: A0A0X1KKJ0
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1432656:X802 RS07130
gene id: 1432656:X802_RS07130
uniprot id: A0A0X1KL54
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1432656:X802 RS03980
gene id: 1432656:X802_RS03980
uniprot id: A0A0X1KJJ6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1432656:X802 RS06770
gene id: 1432656:X802_RS06770
uniprot id: A0A0X1KKY7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1432656:X802 RS07125
gene id: 1432656:X802_RS07125
uniprot id: A0A0X1KL39
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Binds 1 pyruvoyl group covalently per subunit.

1432656:X802 RS09345
gene id: 1432656:X802_RS09345
uniprot id: A0A0X1KM88
names: Similarity
messages: Belongs to the PDCD5 family.

1432656:X802 RS06055
gene id: 1432656:X802_RS06055
uniprot id: A0A0X1KKM6
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

1432656:X802 RS10460
gene id: 1432656:X802_RS10460
uniprot id: A0A0X1KMX6
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1432656:X802 RS05290
gene id: 1432656:X802_RS05290
uniprot id: A0A0X1KK83
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1432656:X802 RS08455
gene id: 1432656:X802_RS08455
uniprot id: A0A0X1KLW0
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS01130
gene id: 1432656:X802_RS01130
uniprot id: A0A0X1KI61
names: Similarity
messages: Belongs to the peptidase S49 family.

1432656:X802 RS04965
gene id: 1432656:X802_RS04965
uniprot id: A0A0X1KK43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1432656:X802 RS05095
gene id: 1432656:X802_RS05095
uniprot id: A0A0X1KK54
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

1432656:X802 RS03700
gene id: 1432656:X802_RS03700
uniprot id: A0A0X1KJE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

1432656:X802 RS06885
gene id: 1432656:X802_RS06885
uniprot id: A0A0X1KL06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

1432656:X802 RS08595
gene id: 1432656:X802_RS08595
uniprot id: A0A0X1KLX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1432656:X802 RS00650
gene id: 1432656:X802_RS00650
uniprot id: A0A0X1KHY0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1432656:X802 RS09885
gene id: 1432656:X802_RS09885
uniprot id: A0A0X1KMH4
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1432656:X802 RS05560
gene id: 1432656:X802_RS05560
uniprot id: A0A0X1KNE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1432656:X802 RS01690
gene id: 1432656:X802_RS01690
uniprot id: A0A0X1KIF8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1432656:X802 RS07810
gene id: 1432656:X802_RS07810
uniprot id: A0A0X1KLI4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1432656:X802 RS01790
gene id: 1432656:X802_RS01790
uniprot id: A0A0X1KIK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

1432656:X802 RS00045
gene id: 1432656:X802_RS00045
uniprot id: A0A0X1KHM2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

1432656:X802 RS04945
gene id: 1432656:X802_RS04945
uniprot id: A0A0X1KK64
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1432656:X802 RS02375
gene id: 1432656:X802_RS02375
uniprot id: A0A0X1KIT4
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS02170
gene id: 1432656:X802_RS02170
uniprot id: A0A0X1KIQ0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1432656:X802 RS02060
gene id: 1432656:X802_RS02060
uniprot id: A0A0X1KIL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

1432656:X802 RS06610
gene id: 1432656:X802_RS06610
uniprot id: A0A0X1KKV6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS07700
gene id: 1432656:X802_RS07700
uniprot id: A0A0X1KLG2
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1432656:X802 RS01340
gene id: 1432656:X802_RS01340
uniprot id: A0A0X1KIA1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1432656:X802 RS04170
gene id: 1432656:X802_RS04170
uniprot id: A0A0X1KJP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1432656:X802 RS10030
gene id: 1432656:X802_RS10030
uniprot id: A0A0X1KMN8
names: Similarity
messages: Belongs to the peptidase S9C family.

1432656:X802 RS06970
gene id: 1432656:X802_RS06970
uniprot id: A0A0X1KL55
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1432656:X802 RS03525
gene id: 1432656:X802_RS03525
uniprot id: A0A0X1KJD7
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS02760
gene id: 1432656:X802_RS02760
uniprot id: A0A0X1KIZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1432656:X802 RS06715
gene id: 1432656:X802_RS06715
uniprot id: A0A0X1KL12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1432656:X802 RS03665
gene id: 1432656:X802_RS03665
uniprot id: A0A0X1KJH3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1432656:X802 RS00190
gene id: 1432656:X802_RS00190
uniprot id: A0A0X1KHQ0
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1432656:X802 RS06175
gene id: 1432656:X802_RS06175
uniprot id: A0A0X1KKP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

1432656:X802 RS05305
gene id: 1432656:X802_RS05305
uniprot id: A0A0X1KK86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1432656:X802 RS03970
gene id: 1432656:X802_RS03970
uniprot id: A0A0X1KJM3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1432656:X802 RS00375
gene id: 1432656:X802_RS00375
uniprot id: A0A0X1KHT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1432656:X802 RS01570
gene id: 1432656:X802_RS01570
uniprot id: A0A0X1KIG8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

1432656:X802 RS06310
gene id: 1432656:X802_RS06310
uniprot id: A0A0X1KKP4
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS05275
gene id: 1432656:X802_RS05275
uniprot id: A0A0X1KK84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

1432656:X802 RS10165
gene id: 1432656:X802_RS10165
uniprot id: A0A0X1KMP3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

1432656:X802 RS05300
gene id: 1432656:X802_RS05300
uniprot id: A0A0X1KK91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1432656:X802 RS06375
gene id: 1432656:X802_RS06375
uniprot id: A0A0X1KKR2
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.

1432656:X802 RS08380
gene id: 1432656:X802_RS08380
uniprot id: A0A0X1KLR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1432656:X802 RS08050
gene id: 1432656:X802_RS08050
uniprot id: A0A0X1KLK7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

1432656:X802 RS10190
gene id: 1432656:X802_RS10190
uniprot id: A0A0X1KMQ2
names: Similarity
messages: Belongs to the peptidase U62 family.

1432656:X802 RS07715
gene id: 1432656:X802_RS07715
uniprot id: A0A0X1KLJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

1432656:X802 RS07570
gene id: 1432656:X802_RS07570
uniprot id: A0A0X1KLE7
names: Similarity
messages: Belongs to the UPF0047 family.

1432656:X802 RS09725
gene id: 1432656:X802_RS09725
uniprot id: A0A0X1KMG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1432656:X802 RS03565
gene id: 1432656:X802_RS03565
uniprot id: A0A0X1KJD4
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1432656:X802 RS01985
gene id: 1432656:X802_RS01985
uniprot id: A0A0X1KIL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily.
messages: Cytoplasm
messages: Homodimer.

1432656:X802 RS04775
gene id: 1432656:X802_RS04775
uniprot id: A0A0X1KJZ0
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS02685
gene id: 1432656:X802_RS02685
uniprot id: A0A0X1KIY7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1432656:X802 RS01680
gene id: 1432656:X802_RS01680
uniprot id: A0A0X1KII8
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

1432656:X802 RS05330
gene id: 1432656:X802_RS05330
uniprot id: A0A0X1KK94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1432656:X802 RS07450
gene id: 1432656:X802_RS07450
uniprot id: A0A0X1KLE3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1432656:X802 RS09420
gene id: 1432656:X802_RS09420
uniprot id: A0A0X1KMA5
names: Similarity
messages: Belongs to the UPF0248 family.

1432656:X802 RS00575
gene id: 1432656:X802_RS00575
uniprot id: A0A0X1KHY7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

1432656:X802 RS06140
gene id: 1432656:X802_RS06140
uniprot id: A0A0X1KKL4
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

1432656:X802 RS04780
gene id: 1432656:X802_RS04780
uniprot id: A0A0X1KK33
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS04480
gene id: 1432656:X802_RS04480
uniprot id: A0A0X1KJX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1432656:X802 RS03550
gene id: 1432656:X802_RS03550
uniprot id: A0A0X1KJE0
names: Similarity
messages: Belongs to the HupF/HypC family.

1432656:X802 RS04685
gene id: 1432656:X802_RS04685
uniprot id: A0A0X1KK11
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1432656:X802 RS08055
gene id: 1432656:X802_RS08055
uniprot id: A0A0X1KLM7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1432656:X802 RS08965
gene id: 1432656:X802_RS08965
uniprot id: A0A0X1KM41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

1432656:X802 RS03650
gene id: 1432656:X802_RS03650
uniprot id: A0A0X1KJD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer. Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.

1432656:X802 RS00010
gene id: 1432656:X802_RS00010
uniprot id: A0A0X1KHM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

1432656:X802 RS09745
gene id: 1432656:X802_RS09745
uniprot id: A0A0X1KMG9
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS05355
gene id: 1432656:X802_RS05355
uniprot id: A0A0X1KKB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1432656:X802 RS05370
gene id: 1432656:X802_RS05370
uniprot id: A0A0X1KKD8
names: Similarity
messages: Belongs to the acylphosphatase family.

1432656:X802 RS02745
gene id: 1432656:X802_RS02745
uniprot id: A0A0X1KIY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

1432656:X802 RS08950
gene id: 1432656:X802_RS08950
uniprot id: A0A0X1KM13
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS07210
gene id: 1432656:X802_RS07210
uniprot id: A0A0X1KL99
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1432656:X802 RS01220
gene id: 1432656:X802_RS01220
uniprot id: A0A0X1KI99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

1432656:X802 RS10530
gene id: 1432656:X802_RS10530
uniprot id: A0A0X1KN09
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1432656:X802 RS01735
gene id: 1432656:X802_RS01735
uniprot id: A0A0X1KIJ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS01900
gene id: 1432656:X802_RS01900
uniprot id: A0A0X1KIJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1432656:X802 RS05645
gene id: 1432656:X802_RS05645
uniprot id: A0A0X1KKH2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS04180
gene id: 1432656:X802_RS04180
uniprot id: A0A0X1KJR5
names: Similarity
messages: Belongs to the MoaD family.

1432656:X802 RS07200
gene id: 1432656:X802_RS07200
uniprot id: A0A0X1KL76
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

1432656:X802 RS03180
gene id: 1432656:X802_RS03180
uniprot id: A0A0X1KJ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

1432656:X802 RS01565
gene id: 1432656:X802_RS01565
uniprot id: A0A0X1KID5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

1432656:X802 RS06860
gene id: 1432656:X802_RS06860
uniprot id: A0A0X1KL31
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1432656:X802 RS02370
gene id: 1432656:X802_RS02370
uniprot id: A0A0X1KIT2
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS01435
gene id: 1432656:X802_RS01435
uniprot id: A0A0X1KIC1
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

1432656:X802 RS06075
gene id: 1432656:X802_RS06075
uniprot id: A0A0X1KKM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

1432656:X802 RS09720
gene id: 1432656:X802_RS09720
uniprot id: A0A0X1KMF7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1432656:X802 RS07930
gene id: 1432656:X802_RS07930
uniprot id: A0A0X1KLJ0
names: Subcellular Location Annotation
messages: Cell membrane

1432656:X802 RS01910
gene id: 1432656:X802_RS01910
uniprot id: A0A0X1KIJ9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1432656:X802 RS10200
gene id: 1432656:X802_RS10200
uniprot id: A0A0X1KMM5
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1432656:X802 RS10355
gene id: 1432656:X802_RS10355
uniprot id: A0A0X1KMS6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

1432656:X802 RS10385
gene id: 1432656:X802_RS10385
uniprot id: A0A0X1KMW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1432656:X802 RS04985
gene id: 1432656:X802_RS04985
uniprot id: A0A0X1KK51
names: Similarity
messages: Belongs to the UPF0047 family.

1432656:X802 RS03630
gene id: 1432656:X802_RS03630
uniprot id: A0A0X1KJC9
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1432656:X802 RS09150
gene id: 1432656:X802_RS09150
uniprot id: A0A0X1KM67
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1432656:X802 RS09230
gene id: 1432656:X802_RS09230
uniprot id: A0A0X1KM91
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1432656:X802 RS02390
gene id: 1432656:X802_RS02390
uniprot id: A0A0X1KIV5
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

1432656:X802 RS05870
gene id: 1432656:X802_RS05870
uniprot id: A0A0X1KKI0
names: Similarity
messages: Belongs to the UPF0173 family.

1432656:X802 RS06040
gene id: 1432656:X802_RS06040
uniprot id: A0A0X1KKK8
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

1432656:X802 RS03270
gene id: 1432656:X802_RS03270
uniprot id: A0A0X1KJ58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

1432656:X802 RS06105
gene id: 1432656:X802_RS06105
uniprot id: A0A0X1KKK9
names: Similarity
messages: Belongs to the DtxR/MntR family.

1432656:X802 RS06110
gene id: 1432656:X802_RS06110
uniprot id: A0A0X1KKQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1432656:X802 RS03110
gene id: 1432656:X802_RS03110
uniprot id: A0A0X1KJ60
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

1432656:X802 RS04460
gene id: 1432656:X802_RS04460
uniprot id: A0A0X1KJS7
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

1432656:X802 RS03105
gene id: 1432656:X802_RS03105
uniprot id: A0A0X1KJ65
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1432656:X802 RS00275
gene id: 1432656:X802_RS00275
uniprot id: A0A0X1KHS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1432656:X802 RS05090
gene id: 1432656:X802_RS05090
uniprot id: A0A0X1KK55
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1432656:X802 RS09540
gene id: 1432656:X802_RS09540
uniprot id: A0A0X1KMC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

1432656:X802 RS10465
gene id: 1432656:X802_RS10465
uniprot id: A0A0X1KMV3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

1432656:X802 RS03480
gene id: 1432656:X802_RS03480
uniprot id: A0A0X1KJA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS05655
gene id: 1432656:X802_RS05655
uniprot id: A0A0X1KKE8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS02315
gene id: 1432656:X802_RS02315
uniprot id: A0A0X1KIS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1432656:X802 RS08320
gene id: 1432656:X802_RS08320
uniprot id: A0A0X1KLP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

1432656:X802 RS02970
gene id: 1432656:X802_RS02970
uniprot id: A0A0X1KJ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1432656:X802 RS05635
gene id: 1432656:X802_RS05635
uniprot id: A0A0X1KKD5
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS04890
gene id: 1432656:X802_RS04890
uniprot id: A0A0X1KK09
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1432656:X802 RS05360
gene id: 1432656:X802_RS05360
uniprot id: A0A0X1KK98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

1432656:X802 RS01210
gene id: 1432656:X802_RS01210
uniprot id: A0A0X1KI84
names: Similarity
messages: Belongs to the UPF0235 family.

1432656:X802 RS00565
gene id: 1432656:X802_RS00565
uniprot id: A0A0X1KHX5
names: Similarity
messages: Belongs to the pyruvate kinase family.

1432656:X802 RS06975
gene id: 1432656:X802_RS06975
uniprot id: A0A0X1KL34
names: Similarity
messages: Belongs to the UPF0146 family.

1432656:X802 RS08485
gene id: 1432656:X802_RS08485
uniprot id: A0A0X1KLV5
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS01705
gene id: 1432656:X802_RS01705
uniprot id: A0A0X1KIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

1432656:X802 RS06170
gene id: 1432656:X802_RS06170
uniprot id: A0A0X1KKR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1432656:X802 RS04340
gene id: 1432656:X802_RS04340
uniprot id: A0A0X1KJT3
names: Similarity
messages: Belongs to the UPF0111 family.

1432656:X802 RS01040
gene id: 1432656:X802_RS01040
uniprot id: A0A0X1KI35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerA subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1432656:X802 RS05440
gene id: 1432656:X802_RS05440
uniprot id: A0A0X1KKB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1432656:X802 RS02295
gene id: 1432656:X802_RS02295
uniprot id: A0A0X1KIU2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

1432656:X802 RS01385
gene id: 1432656:X802_RS01385
uniprot id: A0A0X1KIB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1432656:X802 RS08680
gene id: 1432656:X802_RS08680
uniprot id: A0A0X1KLW3
names: Similarity
messages: Belongs to the peptidase C56 family.

1432656:X802 RS07050
gene id: 1432656:X802_RS07050
uniprot id: A0A0X1KL36
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1432656:X802 RS05375
gene id: 1432656:X802_RS05375
uniprot id: A0A0X1KKB4
names: Similarity
messages: Belongs to the CutA family.

1432656:X802 RS02055
gene id: 1432656:X802_RS02055
uniprot id: A0A0X1KIN9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

1432656:X802 RS09765
gene id: 1432656:X802_RS09765
uniprot id: A0A0X1KMF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1432656:X802 RS07355
gene id: 1432656:X802_RS07355
uniprot id: A0A0X1KLA9
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS08750
gene id: 1432656:X802_RS08750
uniprot id: A0A0X1KM04
names: Similarity
messages: Belongs to the NodU/CmcH family.

1432656:X802 RS04445
gene id: 1432656:X802_RS04445
uniprot id: A0A0X1KJT1
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

1432656:X802 RS08075
gene id: 1432656:X802_RS08075
uniprot id: A0A0X1KLN5
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS08025
gene id: 1432656:X802_RS08025
uniprot id: A0A0X1KLM5
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS07365
gene id: 1432656:X802_RS07365
uniprot id: A0A0X1KL92
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1432656:X802 RS00865
gene id: 1432656:X802_RS00865
uniprot id: A0A0X1KI18
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS08745
gene id: 1432656:X802_RS08745
uniprot id: A0A0X1KLX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1432656:X802 RS03445
gene id: 1432656:X802_RS03445
uniprot id: A0A0X1KJ85
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1432656:X802 RS05910
gene id: 1432656:X802_RS05910
uniprot id: A0A0X1KKI7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1432656:X802 RS01300
gene id: 1432656:X802_RS01300
uniprot id: A0A0X1KI85
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

1432656:X802 RS00485
gene id: 1432656:X802_RS00485
uniprot id: A0A0X1KHW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1432656:X802 RS02140
gene id: 1432656:X802_RS02140
uniprot id: A0A0X1KIN8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS07205
gene id: 1432656:X802_RS07205
uniprot id: A0A0X1KL63
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1432656:X802 RS09355
gene id: 1432656:X802_RS09355
uniprot id: A0A0X1KM95
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1432656:X802 RS01145
gene id: 1432656:X802_RS01145
uniprot id: A0A0X1KI65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

1432656:X802 RS05475
gene id: 1432656:X802_RS05475
uniprot id: A0A0X1KKC6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS02890
gene id: 1432656:X802_RS02890
uniprot id: A0A0X1KJ13
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS03225
gene id: 1432656:X802_RS03225
uniprot id: A0A0X1KJ74
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS08140
gene id: 1432656:X802_RS08140
uniprot id: A0A0X1KNB6
names: Similarity
messages: Belongs to the MCM family.

1432656:X802 RS10450
gene id: 1432656:X802_RS10450
uniprot id: A0A0X1KMY5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1432656:X802 RS03610
gene id: 1432656:X802_RS03610
uniprot id: A0A0X1KJG1
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1432656:X802 RS06360
gene id: 1432656:X802_RS06360
uniprot id: A0A0X1KKQ7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

1432656:X802 RS05225
gene id: 1432656:X802_RS05225
uniprot id: A0A0X1KK97
names: Similarity
messages: Belongs to the class-I fumarase family.

1432656:X802 RS05265
gene id: 1432656:X802_RS05265
uniprot id: A0A0X1KKA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

1432656:X802 RS03195
gene id: 1432656:X802_RS03195
uniprot id: A0A0X1KJ56
names: Subcellular Location Annotation
messages: Nucleus

1432656:X802 RS03120
gene id: 1432656:X802_RS03120
uniprot id: A0A0X1KJ73
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1432656:X802 RS09535
gene id: 1432656:X802_RS09535
uniprot id: A0A0X1KME4
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1432656:X802 RS01875
gene id: 1432656:X802_RS01875
uniprot id: A0A0X1KII2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS01290
gene id: 1432656:X802_RS01290
uniprot id: A0A0X1KI89
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

1432656:X802 RS09835
gene id: 1432656:X802_RS09835
uniprot id: A0A0X1KMG4
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1432656:X802 RS02200
gene id: 1432656:X802_RS02200
uniprot id: A0A0X1KIQ8
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

1432656:X802 RS03470
gene id: 1432656:X802_RS03470
uniprot id: A0A0X1KJ87
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS04515
gene id: 1432656:X802_RS04515
uniprot id: A0A0X1KJY0
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1432656:X802 RS03420
gene id: 1432656:X802_RS03420
uniprot id: A0A0X1KJ75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1432656:X802 RS05220
gene id: 1432656:X802_RS05220
uniprot id: A0A0X1KK85
names: Similarity
messages: Belongs to the malic enzymes family.

1432656:X802 RS04435
gene id: 1432656:X802_RS04435
uniprot id: A0A0X1KJW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

1432656:X802 RS01175
gene id: 1432656:X802_RS01175
uniprot id: A0A0X1KI60
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS06580
gene id: 1432656:X802_RS06580
uniprot id: A0A0X1KKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclic 2,3-diphosphoglycerate synthetase family.
messages: Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP.
messages: Cytoplasm

1432656:X802 RS02985
gene id: 1432656:X802_RS02985
uniprot id: A0A0X1KJ42
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1432656:X802 RS05555
gene id: 1432656:X802_RS05555
uniprot id: A0A0X1KKB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1432656:X802 RS09340
gene id: 1432656:X802_RS09340
uniprot id: A0A0X1KM79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

1432656:X802 RS03900
gene id: 1432656:X802_RS03900
uniprot id: A0A0X1KJK7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1432656:X802 RS06280
gene id: 1432656:X802_RS06280
uniprot id: A0A0X1KKT2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

1432656:X802 RS04525
gene id: 1432656:X802_RS04525
uniprot id: A0A0X1KJU5
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1432656:X802 RS05835
gene id: 1432656:X802_RS05835
uniprot id: A0A0X1KKH0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

1432656:X802 RS10300
gene id: 1432656:X802_RS10300
uniprot id: A0A0X1KMT0
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1432656:X802 RS09285
gene id: 1432656:X802_RS09285
uniprot id: A0A0X1KM69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1432656:X802 RS07510
gene id: 1432656:X802_RS07510
uniprot id: A0A0X1KLD9
names: Similarity
messages: Belongs to the UPF0145 family.

1432656:X802 RS04770
gene id: 1432656:X802_RS04770
uniprot id: A0A0X1KK14
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1432656:X802 RS02080
gene id: 1432656:X802_RS02080
uniprot id: A0A0X1KIN0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS02875
gene id: 1432656:X802_RS02875
uniprot id: A0A0X1KJ12
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

1432656:X802 RS10020
gene id: 1432656:X802_RS10020
uniprot id: A0A0X1KMM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1432656:X802 RS01270
gene id: 1432656:X802_RS01270
uniprot id: A0A0X1KI78
names: Similarity
messages: Belongs to the arginase family.

1432656:X802 RS04495
gene id: 1432656:X802_RS04495
uniprot id: A0A0X1KJV2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1432656:X802 RS04465
gene id: 1432656:X802_RS04465
uniprot id: A0A0X1KJX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1432656:X802 RS03605
gene id: 1432656:X802_RS03605
uniprot id: A0A0X1KJE3
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1432656:X802 RS08740
gene id: 1432656:X802_RS08740
uniprot id: A0A0X1KLZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1432656:X802 RS05640
gene id: 1432656:X802_RS05640
uniprot id: A0A0X1KKD6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS06385
gene id: 1432656:X802_RS06385
uniprot id: A0A0X1KKV4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1432656:X802 RS04085
gene id: 1432656:X802_RS04085
uniprot id: A0A0X1KJN4
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS03265
gene id: 1432656:X802_RS03265
uniprot id: A0A0X1KJ72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

1432656:X802 RS01525
gene id: 1432656:X802_RS01525
uniprot id: A0A0X1KIF3
names: Similarity
messages: Belongs to the AOR/FOR family.

1432656:X802 RS03070
gene id: 1432656:X802_RS03070
uniprot id: A0A0X1KJ35
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1432656:X802 RS05140
gene id: 1432656:X802_RS05140
uniprot id: A0A0X1KK75
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1432656:X802 RS09980
gene id: 1432656:X802_RS09980
uniprot id: A0A0X1KML9
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS05810
gene id: 1432656:X802_RS05810
uniprot id: A0A0X1KKH1
names: Similarity
messages: Belongs to the AOR/FOR family.

1432656:X802 RS00355
gene id: 1432656:X802_RS00355
uniprot id: A0A0X1KHS9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS08035
gene id: 1432656:X802_RS08035
uniprot id: A0A0X1KLN0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

1432656:X802 RS08280
gene id: 1432656:X802_RS08280
uniprot id: A0A0X1KLS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1432656:X802 RS10425
gene id: 1432656:X802_RS10425
uniprot id: A0A0X1KMY3
names: Similarity
messages: Belongs to the UPF0179 family.

1432656:X802 RS08920
gene id: 1432656:X802_RS08920
uniprot id: A0A0X1KM06
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1432656:X802 RS00400
gene id: 1432656:X802_RS00400
uniprot id: A0A0X1KHT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1432656:X802 RS00235
gene id: 1432656:X802_RS00235
uniprot id: A0A0X1KHR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carbohydrate kinase PfkC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
messages: Cytoplasm

1432656:X802 RS04235
gene id: 1432656:X802_RS04235
uniprot id: A0A0X1KJR4
names: Similarity
messages: Belongs to the UPF0147 family.

1432656:X802 RS03005
gene id: 1432656:X802_RS03005
uniprot id: A0A0X1KJ25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1432656:X802 RS09930
gene id: 1432656:X802_RS09930
uniprot id: A0A0X1KMM6
names: Similarity
messages: Belongs to the glutaredoxin family.

1432656:X802 RS07430
gene id: 1432656:X802_RS07430
uniprot id: A0A0X1KL98
names: Similarity
messages: Belongs to the UPF0128 family.

1432656:X802 RS02485
gene id: 1432656:X802_RS02485
uniprot id: A0A0X1KIX1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1432656:X802 RS02285
gene id: 1432656:X802_RS02285
uniprot id: A0A0X1KIT7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS08560
gene id: 1432656:X802_RS08560
uniprot id: A0A0X1KLT9
names: Similarity
messages: Belongs to the HypE family.

1432656:X802 RS07915
gene id: 1432656:X802_RS07915
uniprot id: A0A0X1KLK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1432656:X802 RS08475
gene id: 1432656:X802_RS08475
uniprot id: A0A0X1KLU1
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS02535
gene id: 1432656:X802_RS02535
uniprot id: A0A0X1KIY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1432656:X802 RS01835
gene id: 1432656:X802_RS01835
uniprot id: A0A0X1KIJ6
names: Similarity
messages: Belongs to the DEAD box helicase family.

1432656:X802 RS01205
gene id: 1432656:X802_RS01205
uniprot id: A0A0X1KI63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

1432656:X802 RS08300
gene id: 1432656:X802_RS08300
uniprot id: A0A0X1KLN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

1432656:X802 RS03590
gene id: 1432656:X802_RS03590
uniprot id: A0A0X1KJD3
names: Similarity
messages: Belongs to the HypE family.

1432656:X802 RS10275
gene id: 1432656:X802_RS10275
uniprot id: A0A0X1KMS2
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS01345
gene id: 1432656:X802_RS01345
uniprot id: A0A0X1KIA2
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1432656:X802 RS00475
gene id: 1432656:X802_RS00475
uniprot id: A0A0X1KHV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1432656:X802 RS02400
gene id: 1432656:X802_RS02400
uniprot id: A0A0X1KIW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS06565
gene id: 1432656:X802_RS06565
uniprot id: A0A0X1KKY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1432656:X802 RS02935
gene id: 1432656:X802_RS02935
uniprot id: A0A0X1KJ32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1432656:X802 RS05985
gene id: 1432656:X802_RS05985
uniprot id: A0A0X1KKK1
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

1432656:X802 RS09135
gene id: 1432656:X802_RS09135
uniprot id: A0A0X1KM83
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS02050
gene id: 1432656:X802_RS02050
uniprot id: A0A0X1KIL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

1432656:X802 RS05495
gene id: 1432656:X802_RS05495
uniprot id: A0A0X1KKD1
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1432656:X802 RS10135
gene id: 1432656:X802_RS10135
uniprot id: A0A0X1KMP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

1432656:X802 RS07605
gene id: 1432656:X802_RS07605
uniprot id: A0A0X1KLD6
names: Similarity
messages: Belongs to the SfsA family.

1432656:X802 RS07095
gene id: 1432656:X802_RS07095
uniprot id: A0A0X1KL60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1432656:X802 RS02995
gene id: 1432656:X802_RS02995
uniprot id: A0A0X1KJ17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1432656:X802 RS06825
gene id: 1432656:X802_RS06825
uniprot id: A0A0X1KL14
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1432656:X802 RS09090
gene id: 1432656:X802_RS09090
uniprot id: A0A0X1KM64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1432656:X802 RS03280
gene id: 1432656:X802_RS03280
uniprot id: A0A0X1KJ88
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1432656:X802 RS07850
gene id: 1432656:X802_RS07850
uniprot id: A0A0X1KLH3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

1432656:X802 RS00300
gene id: 1432656:X802_RS00300
uniprot id: A0A0X1KHS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1432656:X802 RS06980
gene id: 1432656:X802_RS06980
uniprot id: A0A0X1KL42
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS05335
gene id: 1432656:X802_RS05335
uniprot id: A0A0X1KK93
names: Similarity
messages: Belongs to the UPF0216 family.

1432656:X802 RS02410
gene id: 1432656:X802_RS02410
uniprot id: A0A0X1KIR6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1432656:X802 RS03875
gene id: 1432656:X802_RS03875
uniprot id: A0A0X1KJK3
names: Similarity
messages: Belongs to the UPF0252 family.

1432656:X802 RS08020
gene id: 1432656:X802_RS08020
uniprot id: A0A0X1KLQ4
names: Similarity
messages: Belongs to the UPF0200 family.

1432656:X802 RS07100
gene id: 1432656:X802_RS07100
uniprot id: A0A0X1KL51
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1432656:X802 RS00595
gene id: 1432656:X802_RS00595
uniprot id: A0A0X1KHX1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1432656:X802 RS05125
gene id: 1432656:X802_RS05125
uniprot id: A0A0X1KK58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1432656:X802 RS08405
gene id: 1432656:X802_RS08405
uniprot id: A0A0X1KLS4
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1432656:X802 RS07110
gene id: 1432656:X802_RS07110
uniprot id: A0A0X1KL78
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS02440
gene id: 1432656:X802_RS02440
uniprot id: A0A0X1KIU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1432656:X802 RS08315
gene id: 1432656:X802_RS08315
uniprot id: A0A0X1KLQ6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Potential transporter for phosphate.

1432656:X802 RS03425
gene id: 1432656:X802_RS03425
uniprot id: A0A0X1KJC3
names: Similarity
messages: Belongs to the UPF0175 family.

1432656:X802 RS05075
gene id: 1432656:X802_RS05075
uniprot id: A0A0X1KK78
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

1432656:X802 RS06995
gene id: 1432656:X802_RS06995
uniprot id: A0A0X1KL58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1432656:X802 RS05950
gene id: 1432656:X802_RS05950
uniprot id: A0A0X1KKK5
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS08760
gene id: 1432656:X802_RS08760
uniprot id: A0A0X1KLY1
names: Similarity
messages: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.

1432656:X802 RS03705
gene id: 1432656:X802_RS03705
uniprot id: A0A0X1KJG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

1432656:X802 RS04630
gene id: 1432656:X802_RS04630
uniprot id: A0A0X1KJV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1432656:X802 RS03415
gene id: 1432656:X802_RS03415
uniprot id: A0A0X1KJA5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1432656:X802 RS01925
gene id: 1432656:X802_RS01925
uniprot id: A0A0X1KIL1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1432656:X802 RS00530
gene id: 1432656:X802_RS00530
uniprot id: A0A0X1KHW6
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS04590
gene id: 1432656:X802_RS04590
uniprot id: A0A0X1KJV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Forms a Heterooligomeric complex of two stacked eight-membered rings.
messages: Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.

1432656:X802 RS04885
gene id: 1432656:X802_RS04885
uniprot id: A0A0X1KK30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1432656:X802 RS01805
gene id: 1432656:X802_RS01805
uniprot id: A0A0X1KIH2
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS08615
gene id: 1432656:X802_RS08615
uniprot id: A0A0X1KLV4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1432656:X802 RS01855
gene id: 1432656:X802_RS01855
uniprot id: A0A0X1KIK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1432656:X802 RS03190
gene id: 1432656:X802_RS03190
uniprot id: A0A0X1KJ82
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1432656:X802 RS09360
gene id: 1432656:X802_RS09360
uniprot id: A0A0X1KMC2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

1432656:X802 RS02945
gene id: 1432656:X802_RS02945
uniprot id: A0A0X1KJ02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

1432656:X802 RS09855
gene id: 1432656:X802_RS09855
uniprot id: A0A0X1KML2
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1432656:X802 RS07835
gene id: 1432656:X802_RS07835
uniprot id: A0A0X1KLH1
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1432656:X802 RS06180
gene id: 1432656:X802_RS06180
uniprot id: A0A0X1KKQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

1432656:X802 RS07665
gene id: 1432656:X802_RS07665
uniprot id: A0A0X1KLI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP-dependent glucokinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the ADP-dependent phosphorylation of D-glucose to D-glucose 6-phosphate and glucosamine to glucosamine 6-phosphate.
messages: Cytoplasm

1432656:X802 RS07795
gene id: 1432656:X802_RS07795
uniprot id: A0A0X1KLH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1432656:X802 RS05390
gene id: 1432656:X802_RS05390
uniprot id: A0A0X1KKA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1432656:X802 RS06545
gene id: 1432656:X802_RS06545
uniprot id: A0A0X1KKV2
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1432656:X802 RS00255
gene id: 1432656:X802_RS00255
uniprot id: A0A0X1KHQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS01045
gene id: 1432656:X802_RS01045
uniprot id: A0A0X1KI43
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

1432656:X802 RS08820
gene id: 1432656:X802_RS08820
uniprot id: A0A0X1KM25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

1432656:X802 RS07640
gene id: 1432656:X802_RS07640
uniprot id: A0A0X1KLH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-alpha family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1432656:X802 RS01095
gene id: 1432656:X802_RS01095
uniprot id: A0A0X1KI54
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS06550
gene id: 1432656:X802_RS06550
uniprot id: A0A0X1KKW7
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS07035
gene id: 1432656:X802_RS07035
uniprot id: A0A0X1KL40
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1432656:X802 RS04360
gene id: 1432656:X802_RS04360
uniprot id: A0A0X1KJR6
names: Similarity
messages: Belongs to the peptidase S9C family.

1432656:X802 RS09185
gene id: 1432656:X802_RS09185
uniprot id: A0A0X1KM93
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1432656:X802 RS05245
gene id: 1432656:X802_RS05245
uniprot id: A0A0X1KK70
names: Similarity
messages: Belongs to the UPF0111 family.

1432656:X802 RS08890
gene id: 1432656:X802_RS08890
uniprot id: A0A0X1KM11
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

1432656:X802 RS04110
gene id: 1432656:X802_RS04110
uniprot id: A0A0X1KJM0
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS06255
gene id: 1432656:X802_RS06255
uniprot id: A0A0X1KKT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1432656:X802 RS00620
gene id: 1432656:X802_RS00620
uniprot id: A0A0X1KHY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1432656:X802 RS01995
gene id: 1432656:X802_RS01995
uniprot id: A0A0X1KIM1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1432656:X802 RS03250
gene id: 1432656:X802_RS03250
uniprot id: A0A0X1KJ93
names: Similarity
messages: Belongs to the ZPR1 family.

1432656:X802 RS05885
gene id: 1432656:X802_RS05885
uniprot id: A0A0X1KKH6
names: Function
names: Subunit
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1432656:X802 RS07895
gene id: 1432656:X802_RS07895
uniprot id: A0A0X1KLJ6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1432656:X802 RS07580
gene id: 1432656:X802_RS07580
uniprot id: A0A0X1KLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

1432656:X802 RS02405
gene id: 1432656:X802_RS02405
uniprot id: A0A0X1KIU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

1432656:X802 RS07025
gene id: 1432656:X802_RS07025
uniprot id: A0A0X1KL45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1432656:X802 RS07540
gene id: 1432656:X802_RS07540
uniprot id: A0A0X1KLB8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1432656:X802 RS04760
gene id: 1432656:X802_RS04760
uniprot id: A0A0X1KK17
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1432656:X802 RS00310
gene id: 1432656:X802_RS00310
uniprot id: A0A0X1KHS7
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

1432656:X802 RS01155
gene id: 1432656:X802_RS01155
uniprot id: A0A0X1KI74
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS02940
gene id: 1432656:X802_RS02940
uniprot id: A0A0X1KJ21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

1432656:X802 RS10360
gene id: 1432656:X802_RS10360
uniprot id: A0A0X1KMV5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

1432656:X802 RS01540
gene id: 1432656:X802_RS01540
uniprot id: A0A0X1KIE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm

1432656:X802 RS01760
gene id: 1432656:X802_RS01760
uniprot id: A0A0X1KII4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1432656:X802 RS06350
gene id: 1432656:X802_RS06350
uniprot id: A0A0X1KKR4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1432656:X802 RS09630
gene id: 1432656:X802_RS09630
uniprot id: A0A0X1KMF2
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS04510
gene id: 1432656:X802_RS04510
uniprot id: A0A0X1KJT8
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS04165
gene id: 1432656:X802_RS04165
uniprot id: A0A0X1KJR8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1432656:X802 RS06690
gene id: 1432656:X802_RS06690
uniprot id: A0A0X1KL05
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS03410
gene id: 1432656:X802_RS03410
uniprot id: A0A0X1KJB7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1432656:X802 RS02065
gene id: 1432656:X802_RS02065
uniprot id: A0A0X1KIQ1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1432656:X802 RS05525
gene id: 1432656:X802_RS05525
uniprot id: A0A0X1KKE9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1432656:X802 RS03710
gene id: 1432656:X802_RS03710
uniprot id: A0A0X1KJG3
names: Function
messages: Part of a potassium transport system.

1432656:X802 RS01395
gene id: 1432656:X802_RS01395
uniprot id: A0A0X1KIA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1432656:X802 RS07065
gene id: 1432656:X802_RS07065
uniprot id: A0A0X1KL44
names: Function
names: Similarity
messages: Belongs to the UPF0330 family.
messages: Possibly the antitoxin component of a toxin-antitoxin (TA) module.

1432656:X802 RS03260
gene id: 1432656:X802_RS03260
uniprot id: A0A0X1KJA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

1432656:X802 RS04330
gene id: 1432656:X802_RS04330
uniprot id: A0A0X1KJS2
names: Similarity
messages: Belongs to the carbamate kinase family.

1432656:X802 RS07230
gene id: 1432656:X802_RS07230
uniprot id: A0A0X1KL72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1432656:X802 RS01100
gene id: 1432656:X802_RS01100
uniprot id: A0A0X1KI48
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS07785
gene id: 1432656:X802_RS07785
uniprot id: A0A0X1KLH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1432656:X802 RS07225
gene id: 1432656:X802_RS07225
uniprot id: A0A0X1KL67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1432656:X802 RS07545
gene id: 1432656:X802_RS07545
uniprot id: A0A0X1KLD4
names: Similarity
messages: Belongs to the UPF0284 family.

1432656:X802 RS05240
gene id: 1432656:X802_RS05240
uniprot id: A0A0X1KK88
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1432656:X802 RS06270
gene id: 1432656:X802_RS06270
uniprot id: A0A0X1KKP6
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

1432656:X802 RS01470
gene id: 1432656:X802_RS01470
uniprot id: A0A0X1KIE4
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1432656:X802 RS09105
gene id: 1432656:X802_RS09105
uniprot id: A0A0X1KM49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1432656:X802 RS09865
gene id: 1432656:X802_RS09865
uniprot id: A0A0X1KMJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1432656:X802 RS09130
gene id: 1432656:X802_RS09130
uniprot id: A0A0X1KM55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS05855
gene id: 1432656:X802_RS05855
uniprot id: A0A0X1KKI4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1432656:X802 RS07615
gene id: 1432656:X802_RS07615
uniprot id: A0A0X1KLH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1432656:X802 RS06725
gene id: 1432656:X802_RS06725
uniprot id: A0A0X1KKY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

1432656:X802 RS02950
gene id: 1432656:X802_RS02950
uniprot id: A0A0X1KJ43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1432656:X802 RS00360
gene id: 1432656:X802_RS00360
uniprot id: A0A0X1KHU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS08815
gene id: 1432656:X802_RS08815
uniprot id: A0A0X1KLZ8
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS02595
gene id: 1432656:X802_RS02595
uniprot id: A0A0X1KIX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1432656:X802 RS06425
gene id: 1432656:X802_RS06425
uniprot id: A0A0X1KKR7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1432656:X802 RS07440
gene id: 1432656:X802_RS07440
uniprot id: A0A0X1KLA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1432656:X802 RS01250
gene id: 1432656:X802_RS01250
uniprot id: A0A0X1KI75
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1432656:X802 RS04520
gene id: 1432656:X802_RS04520
uniprot id: A0A0X1KJV0
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1432656:X802 RS05630
gene id: 1432656:X802_RS05630
uniprot id: A0A0X1KKF8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS01505
gene id: 1432656:X802_RS01505
uniprot id: A0A0X1KIC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

1432656:X802 RS02805
gene id: 1432656:X802_RS02805
uniprot id: A0A0X1KJ26
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1432656:X802 RS01050
gene id: 1432656:X802_RS01050
uniprot id: A0A0X1KI37
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1432656:X802 RS04440
gene id: 1432656:X802_RS04440
uniprot id: A0A0X1KJU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

1432656:X802 RS10260
gene id: 1432656:X802_RS10260
uniprot id: A0A0X1KMN3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1432656:X802 RS04130
gene id: 1432656:X802_RS04130
uniprot id: A0A0X1KJQ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS02955
gene id: 1432656:X802_RS02955
uniprot id: A0A0X1KJ15
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1432656:X802 RS01775
gene id: 1432656:X802_RS01775
uniprot id: A0A0X1KIH4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

1432656:X802 RS06685
gene id: 1432656:X802_RS06685
uniprot id: A0A0X1KKW9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS01745
gene id: 1432656:X802_RS01745
uniprot id: A0A0X1KIG3
names: Similarity
messages: Belongs to the thymidylate kinase family.

1432656:X802 RS06355
gene id: 1432656:X802_RS06355
uniprot id: A0A0X1KKV3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1432656:X802 RS09690
gene id: 1432656:X802_RS09690
uniprot id: A0A0X1KMH3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1432656:X802 RS00610
gene id: 1432656:X802_RS00610
uniprot id: A0A0X1KHY1
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1432656:X802 RS03205
gene id: 1432656:X802_RS03205
uniprot id: A0A0X1KJ99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1432656:X802 RS07445
gene id: 1432656:X802_RS07445
uniprot id: A0A0X1KLB3
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS03040
gene id: 1432656:X802_RS03040
uniprot id: A0A0X1KJ41
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1432656:X802 RS05595
gene id: 1432656:X802_RS05595
uniprot id: A0A0X1KKC7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.

1432656:X802 RS01860
gene id: 1432656:X802_RS01860
uniprot id: A0A0X1KII9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1432656:X802 RS03670
gene id: 1432656:X802_RS03670
uniprot id: A0A0X1KJF2
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1432656:X802 RS07115
gene id: 1432656:X802_RS07115
uniprot id: A0A0X1KL46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1432656:X802 RS02650
gene id: 1432656:X802_RS02650
uniprot id: A0A0X1KIY0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

1432656:X802 RS07010
gene id: 1432656:X802_RS07010
uniprot id: A0A0X1KL21
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1432656:X802 RS06635
gene id: 1432656:X802_RS06635
uniprot id: A0A0X1KKV8
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

1432656:X802 RS03010
gene id: 1432656:X802_RS03010
uniprot id: A0A0X1KJ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

1432656:X802 RS09815
gene id: 1432656:X802_RS09815
uniprot id: A0A0X1KMH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1432656:X802 RS01780
gene id: 1432656:X802_RS01780
uniprot id: A0A0X1KIJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

1432656:X802 RS08635
gene id: 1432656:X802_RS08635
uniprot id: A0A0X1KLX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal-type GPI family.
messages: Cytoplasm
messages: Homodimer.

1432656:X802 RS08080
gene id: 1432656:X802_RS08080
uniprot id: A0A0X1KLM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1432656:X802 RS05920
gene id: 1432656:X802_RS05920
uniprot id: A0A0X1KKM1
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS00365
gene id: 1432656:X802_RS00365
uniprot id: A0A0X1KHT2
names: Function
messages: Probably involved in the biogenesis of the ribosome.

1432656:X802 RS02555
gene id: 1432656:X802_RS02555
uniprot id: A0A0X1KIW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1432656:X802 RS00295
gene id: 1432656:X802_RS00295
uniprot id: A0A0X1KHR7
names: Similarity
messages: Belongs to the UPF0440 family.

1432656:X802 RS01305
gene id: 1432656:X802_RS01305
uniprot id: A0A0X1KI95
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

1432656:X802 RS10155
gene id: 1432656:X802_RS10155
uniprot id: A0A0X1KML8
names: Similarity
messages: Belongs to the UPF0212 family.

1432656:X802 RS00405
gene id: 1432656:X802_RS00405
uniprot id: A0A0X1KHU2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1432656:X802 RS07655
gene id: 1432656:X802_RS07655
uniprot id: A0A0X1KLE6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1432656:X802 RS02145
gene id: 1432656:X802_RS02145
uniprot id: A0A0X1KIP9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1432656:X802 RS01510
gene id: 1432656:X802_RS01510
uniprot id: A0A0X1KIE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
messages: Homodimer.

1432656:X802 RS06125
gene id: 1432656:X802_RS06125
uniprot id: A0A0X1KKN3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1432656:X802 RS04255
gene id: 1432656:X802_RS04255
uniprot id: A0A0X1KJS3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1432656:X802 RS02905
gene id: 1432656:X802_RS02905
uniprot id: A0A0X1KJ05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1432656:X802 RS06380
gene id: 1432656:X802_RS06380
uniprot id: A0A0X1KKR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1432656:X802 RS04300
gene id: 1432656:X802_RS04300
uniprot id: A0A0X1KJT5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

1432656:X802 RS02795
gene id: 1432656:X802_RS02795
uniprot id: A0A0X1KJ16
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1432656:X802 RS00540
gene id: 1432656:X802_RS00540
uniprot id: A0A0X1KHY3
names: Similarity
messages: Belongs to the RuvB family.

1432656:X802 RS04530
gene id: 1432656:X802_RS04530
uniprot id: A0A0X1KJY3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

1432656:X802 RS01595
gene id: 1432656:X802_RS01595
uniprot id: A0A0X1KIG1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

1432656:X802 RS06185
gene id: 1432656:X802_RS06185
uniprot id: A0A0X1KKP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1432656:X802 RS06805
gene id: 1432656:X802_RS06805
uniprot id: A0A0X1KKY4
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

1432656:X802 RS07145
gene id: 1432656:X802_RS07145
uniprot id: A0A0X1KL74
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

1432656:X802 RS06205
gene id: 1432656:X802_RS06205
uniprot id: A0A0X1KKQ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS00615
gene id: 1432656:X802_RS00615
uniprot id: A0A0X1KHX9
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS02820
gene id: 1432656:X802_RS02820
uniprot id: A0A0X1KJ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1432656:X802 RS07900
gene id: 1432656:X802_RS07900
uniprot id: A0A0X1KLI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

1432656:X802 RS10110
gene id: 1432656:X802_RS10110
uniprot id: A0A0X1KMM1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1432656:X802 RS06050
gene id: 1432656:X802_RS06050
uniprot id: A0A0X1KKP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

1432656:X802 RS04855
gene id: 1432656:X802_RS04855
uniprot id: A0A0X1KK08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

1432656:X802 RS08930
gene id: 1432656:X802_RS08930
uniprot id: A0A0X1KM16
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

1432656:X802 RS04820
gene id: 1432656:X802_RS04820
uniprot id: A0A0X1KK23
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS09705
gene id: 1432656:X802_RS09705
uniprot id: A0A0X1KMF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1432656:X802 RS02070
gene id: 1432656:X802_RS02070
uniprot id: A0A0X1KIM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1432656:X802 RS02965
gene id: 1432656:X802_RS02965
uniprot id: A0A0X1KJ27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

1432656:X802 RS08250
gene id: 1432656:X802_RS08250
uniprot id: A0A0X1KLN1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

1432656:X802 RS00385
gene id: 1432656:X802_RS00385
uniprot id: A0A0X1KHU7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1432656:X802 RS07000
gene id: 1432656:X802_RS07000
uniprot id: A0A0X1KL27
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1432656:X802 RS06675
gene id: 1432656:X802_RS06675
uniprot id: A0A0X1KKY0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS06275
gene id: 1432656:X802_RS06275
uniprot id: A0A0X1KKN9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

1432656:X802 RS01230
gene id: 1432656:X802_RS01230
uniprot id: A0A0X1KI67
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1432656:X802 RS02670
gene id: 1432656:X802_RS02670
uniprot id: A0A0X1KIY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1432656:X802 RS01225
gene id: 1432656:X802_RS01225
uniprot id: A0A0X1KI91
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1432656:X802 RS02900
gene id: 1432656:X802_RS02900
uniprot id: A0A0X1KJ30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1432656:X802 RS03460
gene id: 1432656:X802_RS03460
uniprot id: A0A0X1KJC8
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS05840
gene id: 1432656:X802_RS05840
uniprot id: A0A0X1KKF4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1432656:X802 RS02930
gene id: 1432656:X802_RS02930
uniprot id: A0A0X1KJ28
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

1432656:X802 RS02990
gene id: 1432656:X802_RS02990
uniprot id: A0A0X1KJ33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

1432656:X802 RS06870
gene id: 1432656:X802_RS06870
uniprot id: A0A0X1KL22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1432656:X802 RS01120
gene id: 1432656:X802_RS01120
uniprot id: A0A0X1KI70
names: Subcellular Location Annotation
messages: Membrane

1432656:X802 RS02960
gene id: 1432656:X802_RS02960
uniprot id: A0A0X1KJ57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1432656:X802 RS05185
gene id: 1432656:X802_RS05185
uniprot id: A0A0X1KK66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1432656:X802 RS00335
gene id: 1432656:X802_RS00335
uniprot id: A0A0X1KHT5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS07370
gene id: 1432656:X802_RS07370
uniprot id: A0A0X1KLD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1432656:X802 RS01450
gene id: 1432656:X802_RS01450
uniprot id: A0A0X1KIB4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

1432656:X802 RS08830
gene id: 1432656:X802_RS08830
uniprot id: A0A0X1KLZ3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

1432656:X802 RS02215
gene id: 1432656:X802_RS02215
uniprot id: A0A0X1KIP6
names: Function
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
messages: Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.

1432656:X802 RS04145
gene id: 1432656:X802_RS04145
uniprot id: A0A0X1KJP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1432656:X802 RS07020
gene id: 1432656:X802_RS07020
uniprot id: A0A0X1KL65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1432656:X802 RS02915
gene id: 1432656:X802_RS02915
uniprot id: A0A0X1KJ19
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1432656:X802 RS02750
gene id: 1432656:X802_RS02750
uniprot id: A0A0X1KIW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

1432656:X802 RS06410
gene id: 1432656:X802_RS06410
uniprot id: A0A0X1KKS3
names: Similarity
messages: Belongs to the GARS family.

1432656:X802 RS03785
gene id: 1432656:X802_RS03785
uniprot id: A0A0X1KJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S16 family.
messages: Membrane