143223:B5488 RS01510
gene id: 143223:B5488_RS01510
uniprot id: A0A1M7HWD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

143223:B5488 RS15415
gene id: 143223:B5488_RS15415
uniprot id: A0A1M7NGB3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

143223:B5488 RS01525
gene id: 143223:B5488_RS01525
uniprot id: A0A1M7HWT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

143223:B5488 RS11675
gene id: 143223:B5488_RS11675
uniprot id: A0A1M7MBG1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

143223:B5488 RS01360
gene id: 143223:B5488_RS01360
uniprot id: A0A1M7HUA5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

143223:B5488 RS01655
gene id: 143223:B5488_RS01655
uniprot id: A0A1M7HZ34
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

143223:B5488 RS01480
gene id: 143223:B5488_RS01480
uniprot id: A0A1M7HW61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

143223:B5488 RS07175
gene id: 143223:B5488_RS07175
uniprot id: A0A1M7KJE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

143223:B5488 RS12955
gene id: 143223:B5488_RS12955
uniprot id: A0A1M7MS02
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

143223:B5488 RS06165
gene id: 143223:B5488_RS06165
uniprot id: A0A1M7K5E1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

143223:B5488 RS14875
gene id: 143223:B5488_RS14875
uniprot id: A0A1M7NCK3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

143223:B5488 RS13005
gene id: 143223:B5488_RS13005
uniprot id: A0A1M7MSK0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

143223:B5488 RS07200
gene id: 143223:B5488_RS07200
uniprot id: A0A1M7KKB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

143223:B5488 RS12120
gene id: 143223:B5488_RS12120
uniprot id: A0A1M7MHT3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

143223:B5488 RS01545
gene id: 143223:B5488_RS01545
uniprot id: A0A1M7HX66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

143223:B5488 RS01520
gene id: 143223:B5488_RS01520
uniprot id: A0A1M7HWZ9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

143223:B5488 RS17560
gene id: 143223:B5488_RS17560
uniprot id: A0A1M7NZ54
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

143223:B5488 RS15360
gene id: 143223:B5488_RS15360
uniprot id: A0A1M7NG05
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

143223:B5488 RS04420
gene id: 143223:B5488_RS04420
uniprot id: A0A1M7JBS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

143223:B5488 RS01350
gene id: 143223:B5488_RS01350
uniprot id: A0A1M7HTT5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

143223:B5488 RS15410
gene id: 143223:B5488_RS15410
uniprot id: A0A1M7NH31
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

143223:B5488 RS13790
gene id: 143223:B5488_RS13790
uniprot id: A0A1M7N0T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

143223:B5488 RS01585
gene id: 143223:B5488_RS01585
uniprot id: A0A1M7HXD7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

143223:B5488 RS03225
gene id: 143223:B5488_RS03225
uniprot id: A0A1M7IQJ2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

143223:B5488 RS10040
gene id: 143223:B5488_RS10040
uniprot id: A0A1M7LS55
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

143223:B5488 RS01590
gene id: 143223:B5488_RS01590
uniprot id: A0A1M7HY53
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

143223:B5488 RS10215
gene id: 143223:B5488_RS10215
uniprot id: A0A1M7LUE2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

143223:B5488 RS04655
gene id: 143223:B5488_RS04655
uniprot id: A0A1M7JFT0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

143223:B5488 RS11335
gene id: 143223:B5488_RS11335
uniprot id: A0A1M7M8A6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

143223:B5488 RS06680
gene id: 143223:B5488_RS06680
uniprot id: A0A1M7KDD2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

143223:B5488 RS10370
gene id: 143223:B5488_RS10370
uniprot id: A0A1M7LVZ6
names: Subcellular Location Annotation
messages: Cytoplasm

143223:B5488 RS14410
gene id: 143223:B5488_RS14410
uniprot id: A0A1M7N7X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

143223:B5488 RS01600
gene id: 143223:B5488_RS01600
uniprot id: A0A1M7HXV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

143223:B5488 RS01605
gene id: 143223:B5488_RS01605
uniprot id: A0A1M7HY04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

143223:B5488 RS15405
gene id: 143223:B5488_RS15405
uniprot id: A0A1M7NHP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

143223:B5488 RS13965
gene id: 143223:B5488_RS13965
uniprot id: A0A1M7N481
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

143223:B5488 RS17095
gene id: 143223:B5488_RS17095
uniprot id: A0A1M7NWA7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bTHX family.

143223:B5488 RS05305
gene id: 143223:B5488_RS05305
uniprot id: A0A1M7JQM5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

143223:B5488 RS17775
gene id: 143223:B5488_RS17775
uniprot id: A0A1M7H8Q5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

143223:B5488 RS04465
gene id: 143223:B5488_RS04465
uniprot id: A0A1M7JCL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

143223:B5488 RS01500
gene id: 143223:B5488_RS01500
uniprot id: A0A1M7HW66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

143223:B5488 RS07110
gene id: 143223:B5488_RS07110
uniprot id: A0A1M7KJ41
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

143223:B5488 RS09845
gene id: 143223:B5488_RS09845
uniprot id: A0A1M7LQ36
names: Similarity
messages: Belongs to the thioredoxin family.

143223:B5488 RS01615
gene id: 143223:B5488_RS01615
uniprot id: A0A1M7HY06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

143223:B5488 RS08315
gene id: 143223:B5488_RS08315
uniprot id: A0A1M7L1T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

143223:B5488 RS00100
gene id: 143223:B5488_RS00100
uniprot id: A0A1M7H8Q5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

143223:B5488 RS01610
gene id: 143223:B5488_RS01610
uniprot id: A0A1M7HZ21
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

143223:B5488 RS04425
gene id: 143223:B5488_RS04425
uniprot id: A0A1M7JBY5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

143223:B5488 RS13025
gene id: 143223:B5488_RS13025
uniprot id: A0A1M7MTZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

143223:B5488 RS13540
gene id: 143223:B5488_RS13540
uniprot id: A0A1M7MXY5
names: Similarity
messages: Belongs to the Skp family.

143223:B5488 RS01495
gene id: 143223:B5488_RS01495
uniprot id: A0A1M7HWD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

143223:B5488 RS01540
gene id: 143223:B5488_RS01540
uniprot id: A0A1M7HXW7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

143223:B5488 RS10265
gene id: 143223:B5488_RS10265
uniprot id: A0A1M7LUP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

143223:B5488 RS01550
gene id: 143223:B5488_RS01550
uniprot id: A0A1M7HWZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.