1423720:LA20249 RS11080
gene id: 1423720:LA20249_RS11080
uniprot id: A0A2K9HJH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1423720:LA20249 RS01635
gene id: 1423720:LA20249_RS01635
uniprot id: A0A2K9HGS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1423720:LA20249 RS10965
gene id: 1423720:LA20249_RS10965
uniprot id: A0A2K9HQ13
names: Similarity
messages: Belongs to the peptidase C1 family.

1423720:LA20249 RS07145
gene id: 1423720:LA20249_RS07145
uniprot id: A0A2K9HHD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS10500
gene id: 1423720:LA20249_RS10500
uniprot id: A0A2K9HJ63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1423720:LA20249 RS03015
gene id: 1423720:LA20249_RS03015
uniprot id: A0A2K9HHG4
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS09705
gene id: 1423720:LA20249_RS09705
uniprot id: A0A2K9HPM3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423720:LA20249 RS10205
gene id: 1423720:LA20249_RS10205
uniprot id: A0A2K9HJ11
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1423720:LA20249 RS05025
gene id: 1423720:LA20249_RS05025
uniprot id: A0A2K9HIP8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1423720:LA20249 RS04865
gene id: 1423720:LA20249_RS04865
uniprot id: A0A2K9HG81
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1423720:LA20249 RS02390
gene id: 1423720:LA20249_RS02390
uniprot id: A0A2K9HEX1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1423720:LA20249 RS01900
gene id: 1423720:LA20249_RS01900
uniprot id: A0A2K9HGX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1423720:LA20249 RS04825
gene id: 1423720:LA20249_RS04825
uniprot id: A0A2K9HPZ6
names: Subcellular Location Annotation
messages: cell wall

1423720:LA20249 RS01890
gene id: 1423720:LA20249_RS01890
uniprot id: A0A2K9HEN1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1423720:LA20249 RS05910
gene id: 1423720:LA20249_RS05910
uniprot id: A0A2K9HH84
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS05720
gene id: 1423720:LA20249_RS05720
uniprot id: A0A2K9HIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1423720:LA20249 RS03820
gene id: 1423720:LA20249_RS03820
uniprot id: A0A2K9HMR2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1423720:LA20249 RS11030
gene id: 1423720:LA20249_RS11030
uniprot id: A0A2K9HN38
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1423720:LA20249 RS05855
gene id: 1423720:LA20249_RS05855
uniprot id: A0A2K9HGS6
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1423720:LA20249 RS01460
gene id: 1423720:LA20249_RS01460
uniprot id: A0A2K9HJN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1423720:LA20249 RS10630
gene id: 1423720:LA20249_RS10630
uniprot id: A0A2K9HJB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1423720:LA20249 RS03900
gene id: 1423720:LA20249_RS03900
uniprot id: A0A2K9HG83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1423720:LA20249 RS07835
gene id: 1423720:LA20249_RS07835
uniprot id: A0A2K9HHR6
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS10960
gene id: 1423720:LA20249_RS10960
uniprot id: A0A2K9HRR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S15 family.
messages: Cytoplasm
messages: Homodimer.
messages: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

1423720:LA20249 RS06840
gene id: 1423720:LA20249_RS06840
uniprot id: A0A2K9HNR4
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS10985
gene id: 1423720:LA20249_RS10985
uniprot id: A0A2K9HLI3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1423720:LA20249 RS09340
gene id: 1423720:LA20249_RS09340
uniprot id: A0A2K9HRA9
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

1423720:LA20249 RS03740
gene id: 1423720:LA20249_RS03740
uniprot id: A0A2K9HFM8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1423720:LA20249 RS02225
gene id: 1423720:LA20249_RS02225
uniprot id: A0A2K9HH30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1423720:LA20249 RS01985
gene id: 1423720:LA20249_RS01985
uniprot id: A0A2K9HM55
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423720:LA20249 RS02590
gene id: 1423720:LA20249_RS02590
uniprot id: A0A2K9HF14
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1423720:LA20249 RS09935
gene id: 1423720:LA20249_RS09935
uniprot id: A0A2K9HKT2
names: Similarity
messages: Belongs to the EamA transporter family.

1423720:LA20249 RS00850
gene id: 1423720:LA20249_RS00850
uniprot id: A0A2K9HGN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS03165
gene id: 1423720:LA20249_RS03165
uniprot id: A0A2K9HFB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS06020
gene id: 1423720:LA20249_RS06020
uniprot id: A0A2K9HJ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS00090
gene id: 1423720:LA20249_RS00090
uniprot id: A0A2N9YJR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1423720:LA20249 RS05310
gene id: 1423720:LA20249_RS05310
uniprot id: A0A2K9HGW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1423720:LA20249 RS01720
gene id: 1423720:LA20249_RS01720
uniprot id: A0A2K9HP16
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1423720:LA20249 RS09915
gene id: 1423720:LA20249_RS09915
uniprot id: A0A2K9HPP7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1423720:LA20249 RS07565
gene id: 1423720:LA20249_RS07565
uniprot id: A0A2K9HI25
names: Similarity
messages: Belongs to the peptidase M20A family.

1423720:LA20249 RS01275
gene id: 1423720:LA20249_RS01275
uniprot id: A0A2K9HEC5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1423720:LA20249 RS07590
gene id: 1423720:LA20249_RS07590
uniprot id: A0A2K9HNZ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1423720:LA20249 RS05425
gene id: 1423720:LA20249_RS05425
uniprot id: A0A2K9HGI8
names: Similarity
messages: Belongs to the sigma-54 factor family.

1423720:LA20249 RS08515
gene id: 1423720:LA20249_RS08515
uniprot id: A0A2K9HKC7
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1423720:LA20249 RS00655
gene id: 1423720:LA20249_RS00655
uniprot id: A0A2K9HE20
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS09515
gene id: 1423720:LA20249_RS09515
uniprot id: A0A2K9HIP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1423720:LA20249 RS03730
gene id: 1423720:LA20249_RS03730
uniprot id: A0A2K9HI32
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1423720:LA20249 RS05005
gene id: 1423720:LA20249_RS05005
uniprot id: A0A2K9HN56
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS05595
gene id: 1423720:LA20249_RS05595
uniprot id: A0A2K9HGK6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423720:LA20249 RS05185
gene id: 1423720:LA20249_RS05185
uniprot id: A0A2K9HGU0
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1423720:LA20249 RS10765
gene id: 1423720:LA20249_RS10765
uniprot id: A0A2K9HJB6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1423720:LA20249 RS08065
gene id: 1423720:LA20249_RS08065
uniprot id: A0A2K9HM22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1423720:LA20249 RS03840
gene id: 1423720:LA20249_RS03840
uniprot id: A0A2K9HI49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1423720:LA20249 RS10650
gene id: 1423720:LA20249_RS10650
uniprot id: A0A2K9HPX9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1423720:LA20249 RS05320
gene id: 1423720:LA20249_RS05320
uniprot id: A0A2K9HGG0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1423720:LA20249 RS02105
gene id: 1423720:LA20249_RS02105
uniprot id: A0A2K9HES2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1423720:LA20249 RS04310
gene id: 1423720:LA20249_RS04310
uniprot id: A0A2K9HFY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS04690
gene id: 1423720:LA20249_RS04690
uniprot id: A0A2K9HK83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1423720:LA20249 RS04870
gene id: 1423720:LA20249_RS04870
uniprot id: A0A2K9HG76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1423720:LA20249 RS01350
gene id: 1423720:LA20249_RS01350
uniprot id: A0A2K9HLY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1423720:LA20249 RS05860
gene id: 1423720:LA20249_RS05860
uniprot id: A0A2K9HGR1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1423720:LA20249 RS01830
gene id: 1423720:LA20249_RS01830
uniprot id: A0A2K9HP28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1423720:LA20249 RS02480
gene id: 1423720:LA20249_RS02480
uniprot id: A0A2K9HEY6
names: Similarity
messages: Belongs to the UPF0346 family.

1423720:LA20249 RS08370
gene id: 1423720:LA20249_RS08370
uniprot id: A0A2K9HR13
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1423720:LA20249 RS05920
gene id: 1423720:LA20249_RS05920
uniprot id: A0A2K9HGS8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1423720:LA20249 RS06470
gene id: 1423720:LA20249_RS06470
uniprot id: A0A2K9HJF7
names: Similarity
messages: Belongs to the DtxR/MntR family.

1423720:LA20249 RS07475
gene id: 1423720:LA20249_RS07475
uniprot id: A0A2K9HHJ6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1423720:LA20249 RS01795
gene id: 1423720:LA20249_RS01795
uniprot id: A0A2K9HGV2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1423720:LA20249 RS07580
gene id: 1423720:LA20249_RS07580
uniprot id: A0A2K9HHL3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1423720:LA20249 RS05490
gene id: 1423720:LA20249_RS05490
uniprot id: A0A2K9HQ70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1423720:LA20249 RS03390
gene id: 1423720:LA20249_RS03390
uniprot id: A0A2K9HHW6
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS08755
gene id: 1423720:LA20249_RS08755
uniprot id: A0A2K9HPC2
names: Subcellular Location Annotation
messages: cell wall

1423720:LA20249 RS04110
gene id: 1423720:LA20249_RS04110
uniprot id: A0A2K9HKK3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1423720:LA20249 RS03825
gene id: 1423720:LA20249_RS03825
uniprot id: A0A2K9HFN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1423720:LA20249 RS02870
gene id: 1423720:LA20249_RS02870
uniprot id: A0A2K9HF57
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1423720:LA20249 RS10045
gene id: 1423720:LA20249_RS10045
uniprot id: A0A2K9HIZ1
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS01380
gene id: 1423720:LA20249_RS01380
uniprot id: A0A2K9HEX5
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1423720:LA20249 RS04125
gene id: 1423720:LA20249_RS04125
uniprot id: A0A2K9HGC5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS01915
gene id: 1423720:LA20249_RS01915
uniprot id: A0A2K9HEP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1423720:LA20249 RS01760
gene id: 1423720:LA20249_RS01760
uniprot id: A0A2K9HEL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1423720:LA20249 RS02455
gene id: 1423720:LA20249_RS02455
uniprot id: A0A2K9HH68
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1423720:LA20249 RS10210
gene id: 1423720:LA20249_RS10210
uniprot id: A0A2K9HJ05
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS08340
gene id: 1423720:LA20249_RS08340
uniprot id: A0A2K9HK78
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1423720:LA20249 RS00235
gene id: 1423720:LA20249_RS00235
uniprot id: A0A2K9HK30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS01040
gene id: 1423720:LA20249_RS01040
uniprot id: A0A2K9HGR7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1423720:LA20249 RS05065
gene id: 1423720:LA20249_RS05065
uniprot id: A0A2K9HII2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1423720:LA20249 RS06260
gene id: 1423720:LA20249_RS06260
uniprot id: A0A2K9HH07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1423720:LA20249 RS05690
gene id: 1423720:LA20249_RS05690
uniprot id: A0A2K9HGN1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1423720:LA20249 RS09800
gene id: 1423720:LA20249_RS09800
uniprot id: A0A2K9HIS3
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1423720:LA20249 RS07380
gene id: 1423720:LA20249_RS07380
uniprot id: A0A2K9HJR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS03755
gene id: 1423720:LA20249_RS03755
uniprot id: A0A2K9HPN4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1423720:LA20249 RS05420
gene id: 1423720:LA20249_RS05420
uniprot id: A0A2K9HGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS01755
gene id: 1423720:LA20249_RS01755
uniprot id: A0A2K9HEL7
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1423720:LA20249 RS05450
gene id: 1423720:LA20249_RS05450
uniprot id: A0A2K9HGH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

1423720:LA20249 RS03235
gene id: 1423720:LA20249_RS03235
uniprot id: A0A2K9HFW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1423720:LA20249 RS01475
gene id: 1423720:LA20249_RS01475
uniprot id: A0A2K9HJJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1423720:LA20249 RS04800
gene id: 1423720:LA20249_RS04800
uniprot id: A0A2K9HGM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS07460
gene id: 1423720:LA20249_RS07460
uniprot id: A0A2K9HI08
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS00940
gene id: 1423720:LA20249_RS00940
uniprot id: A0A2K9HNS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS01680
gene id: 1423720:LA20249_RS01680
uniprot id: A0A2K9HEJ5
names: Similarity
messages: Belongs to the YggT family.

1423720:LA20249 RS07920
gene id: 1423720:LA20249_RS07920
uniprot id: A0A2K9HK60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS02195
gene id: 1423720:LA20249_RS02195
uniprot id: A0A2K9HEV3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1423720:LA20249 RS02290
gene id: 1423720:LA20249_RS02290
uniprot id: A0A2K9HFE6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1423720:LA20249 RS05495
gene id: 1423720:LA20249_RS05495
uniprot id: A0A2K9HNB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1423720:LA20249 RS09910
gene id: 1423720:LA20249_RS09910
uniprot id: A0A2K9HRF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS03790
gene id: 1423720:LA20249_RS03790
uniprot id: A0A2K9HFN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1423720:LA20249 RS09840
gene id: 1423720:LA20249_RS09840
uniprot id: A0A2K9HIV0
names: Similarity
messages: Belongs to the asparagine synthetase family.

1423720:LA20249 RS07910
gene id: 1423720:LA20249_RS07910
uniprot id: A0A2K9HLZ9
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS03010
gene id: 1423720:LA20249_RS03010
uniprot id: A0A2K9HK99
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423720:LA20249 RS07050
gene id: 1423720:LA20249_RS07050
uniprot id: A0A2K9HNT4
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS08650
gene id: 1423720:LA20249_RS08650
uniprot id: A0A2K9HR40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS07115
gene id: 1423720:LA20249_RS07115
uniprot id: A0A2K9HJL1
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1423720:LA20249 RS07990
gene id: 1423720:LA20249_RS07990
uniprot id: A0A2K9HHU4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS03500
gene id: 1423720:LA20249_RS03500
uniprot id: A0A2K9HHQ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423720:LA20249 RS05780
gene id: 1423720:LA20249_RS05780
uniprot id: A0A2K9HIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS10030
gene id: 1423720:LA20249_RS10030
uniprot id: A0A2K9HKR2
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1423720:LA20249 RS06360
gene id: 1423720:LA20249_RS06360
uniprot id: A0A2K9HHG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1423720:LA20249 RS04120
gene id: 1423720:LA20249_RS04120
uniprot id: A0A2K9HI97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1423720:LA20249 RS05530
gene id: 1423720:LA20249_RS05530
uniprot id: A0A2K9HGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS06680
gene id: 1423720:LA20249_RS06680
uniprot id: A0A2K9HRZ2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423720:LA20249 RS09135
gene id: 1423720:LA20249_RS09135
uniprot id: A0A2K9HPG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1423720:LA20249 RS04710
gene id: 1423720:LA20249_RS04710
uniprot id: A0A2K9HG59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1423720:LA20249 RS01575
gene id: 1423720:LA20249_RS01575
uniprot id: A0A2K9HEH6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1423720:LA20249 RS04910
gene id: 1423720:LA20249_RS04910
uniprot id: A0A2K9HIF1
names: PTM
names: Subcellular Location Annotation
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm

1423720:LA20249 RS06625
gene id: 1423720:LA20249_RS06625
uniprot id: A0A2K9HJU7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1423720:LA20249 RS03855
gene id: 1423720:LA20249_RS03855
uniprot id: A0A2K9HFQ7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1423720:LA20249 RS08375
gene id: 1423720:LA20249_RS08375
uniprot id: A0A2K9HP81
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1423720:LA20249 RS08145
gene id: 1423720:LA20249_RS08145
uniprot id: A0A2K9HHX2
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS10640
gene id: 1423720:LA20249_RS10640
uniprot id: A0A2K9HJ89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1423720:LA20249 RS00145
gene id: 1423720:LA20249_RS00145
uniprot id: A0A2N9YJR9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1423720:LA20249 RS01145
gene id: 1423720:LA20249_RS01145
uniprot id: A0A2K9HGJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS01500
gene id: 1423720:LA20249_RS01500
uniprot id: A0A2K9HEH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1423720:LA20249 RS08670
gene id: 1423720:LA20249_RS08670
uniprot id: A0A2K9HKA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS00595
gene id: 1423720:LA20249_RS00595
uniprot id: A0A2K9HE15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS04705
gene id: 1423720:LA20249_RS04705
uniprot id: A0A2K9HGM0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1423720:LA20249 RS04415
gene id: 1423720:LA20249_RS04415
uniprot id: A0A2K9HG09
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS05210
gene id: 1423720:LA20249_RS05210
uniprot id: A0A2K9HGE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS02620
gene id: 1423720:LA20249_RS02620
uniprot id: A0A2K9HH95
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1423720:LA20249 RS00950
gene id: 1423720:LA20249_RS00950
uniprot id: A0A2K9HE73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1423720:LA20249 RS04395
gene id: 1423720:LA20249_RS04395
uniprot id: A0A2K9HIE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1423720:LA20249 RS00615
gene id: 1423720:LA20249_RS00615
uniprot id: A0A2K9HLQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS00430
gene id: 1423720:LA20249_RS00430
uniprot id: A0A2K9HDY3
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1423720:LA20249 RS01790
gene id: 1423720:LA20249_RS01790
uniprot id: A0A2K9HJQ1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1423720:LA20249 RS03595
gene id: 1423720:LA20249_RS03595
uniprot id: A0A2K9HPL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

1423720:LA20249 RS11120
gene id: 1423720:LA20249_RS11120
uniprot id: A0A2K9HRS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

1423720:LA20249 RS10945
gene id: 1423720:LA20249_RS10945
uniprot id: A0A2K9HJH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS03150
gene id: 1423720:LA20249_RS03150
uniprot id: A0A2K9HFB5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1423720:LA20249 RS04665
gene id: 1423720:LA20249_RS04665
uniprot id: A0A2K9HN19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1423720:LA20249 RS01855
gene id: 1423720:LA20249_RS01855
uniprot id: A0A2K9HH49
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1423720:LA20249 RS04720
gene id: 1423720:LA20249_RS04720
uniprot id: A0A2K9HG56
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
messages: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.

1423720:LA20249 RS05665
gene id: 1423720:LA20249_RS05665
uniprot id: A0A2K9HL61
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1423720:LA20249 RS06190
gene id: 1423720:LA20249_RS06190
uniprot id: A0A2K9HJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1423720:LA20249 RS01465
gene id: 1423720:LA20249_RS01465
uniprot id: A0A2K9HLZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1423720:LA20249 RS07290
gene id: 1423720:LA20249_RS07290
uniprot id: A0A2K9HHX9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1423720:LA20249 RS10670
gene id: 1423720:LA20249_RS10670
uniprot id: A0A2K9HQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1423720:LA20249 RS00120
gene id: 1423720:LA20249_RS00120
uniprot id: A0A2N9YJR4
names: Similarity
messages: Belongs to the UPF0473 family.

1423720:LA20249 RS04795
gene id: 1423720:LA20249_RS04795
uniprot id: A0A2K9HIK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS09475
gene id: 1423720:LA20249_RS09475
uniprot id: A0A2K9HIK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS10280
gene id: 1423720:LA20249_RS10280
uniprot id: A0A2K9HMT6
names: Similarity
messages: Belongs to the EamA transporter family.

1423720:LA20249 RS10195
gene id: 1423720:LA20249_RS10195
uniprot id: A0A2K9HJH3
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1423720:LA20249 RS01070
gene id: 1423720:LA20249_RS01070
uniprot id: A0A2K9HLV3
names: Similarity
messages: Belongs to the peptidase C69 family.

1423720:LA20249 RS05505
gene id: 1423720:LA20249_RS05505
uniprot id: A0A2K9HGI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1423720:LA20249 RS05235
gene id: 1423720:LA20249_RS05235
uniprot id: A0A2K9HIL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

1423720:LA20249 RS11005
gene id: 1423720:LA20249_RS11005
uniprot id: A0A2K9HJG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1423720:LA20249 RS09180
gene id: 1423720:LA20249_RS09180
uniprot id: A0A2K9HR93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS07085
gene id: 1423720:LA20249_RS07085
uniprot id: A0A2K9HHC8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1423720:LA20249 RS02930
gene id: 1423720:LA20249_RS02930
uniprot id: A0A2K9HF75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1423720:LA20249 RS05045
gene id: 1423720:LA20249_RS05045
uniprot id: A0A2K9HGA8
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS00635
gene id: 1423720:LA20249_RS00635
uniprot id: A0A2K9HGJ9
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS05130
gene id: 1423720:LA20249_RS05130
uniprot id: A0A2K9HIS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1423720:LA20249 RS03950
gene id: 1423720:LA20249_RS03950
uniprot id: A0A2K9HG93
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1423720:LA20249 RS10510
gene id: 1423720:LA20249_RS10510
uniprot id: A0A2K9HKX8
names: Similarity
messages: Belongs to the UPF0177 family.

1423720:LA20249 RS02410
gene id: 1423720:LA20249_RS02410
uniprot id: A0A2K9HHE7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS01920
gene id: 1423720:LA20249_RS01920
uniprot id: A0A2K9HEP6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS05520
gene id: 1423720:LA20249_RS05520
uniprot id: A0A2K9HIY7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1423720:LA20249 RS10225
gene id: 1423720:LA20249_RS10225
uniprot id: A0A2K9HJ13
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1423720:LA20249 RS03890
gene id: 1423720:LA20249_RS03890
uniprot id: A0A2K9HHX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1423720:LA20249 RS10970
gene id: 1423720:LA20249_RS10970
uniprot id: A0A2K9HJF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1423720:LA20249 RS05350
gene id: 1423720:LA20249_RS05350
uniprot id: A0A2K9HIN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS02560
gene id: 1423720:LA20249_RS02560
uniprot id: A0A2K9HK42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS05915
gene id: 1423720:LA20249_RS05915
uniprot id: A0A2K9HGU4
names: Subcellular Location Annotation
messages: Cytoplasm

1423720:LA20249 RS01665
gene id: 1423720:LA20249_RS01665
uniprot id: A0A2K9HEJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1423720:LA20249 RS04645
gene id: 1423720:LA20249_RS04645
uniprot id: A0A2K9HG49
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS04640
gene id: 1423720:LA20249_RS04640
uniprot id: A0A2K9HLH2
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS05455
gene id: 1423720:LA20249_RS05455
uniprot id: A0A2K9HL32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

1423720:LA20249 RS09330
gene id: 1423720:LA20249_RS09330
uniprot id: A0A2K9HIK6
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1423720:LA20249 RS10250
gene id: 1423720:LA20249_RS10250
uniprot id: A0A2K9HJ31
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS09850
gene id: 1423720:LA20249_RS09850
uniprot id: A0A2K9HIU3
names: Similarity
messages: Belongs to the universal stress protein A family.

1423720:LA20249 RS05800
gene id: 1423720:LA20249_RS05800
uniprot id: A0A2K9HGR8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1423720:LA20249 RS02665
gene id: 1423720:LA20249_RS02665
uniprot id: A0A2K9HJP8
names: Cofactor
messages: Binds 2 manganese ions per subunit.

1423720:LA20249 RS00110
gene id: 1423720:LA20249_RS00110
uniprot id: A0A2N9YJQ0
names: Similarity
messages: Belongs to the UPF0297 family.

1423720:LA20249 RS08565
gene id: 1423720:LA20249_RS08565
uniprot id: A0A2K9HKA0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1423720:LA20249 RS11490
gene id: 1423720:LA20249_RS11490
uniprot id: A0A2K9HLL7
names: Similarity
messages: Belongs to the peptidase C40 family.

1423720:LA20249 RS02120
gene id: 1423720:LA20249_RS02120
uniprot id: A0A2K9HH08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1423720:LA20249 RS09585
gene id: 1423720:LA20249_RS09585
uniprot id: A0A2K9HIP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS01580
gene id: 1423720:LA20249_RS01580
uniprot id: A0A2K9HJL8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1423720:LA20249 RS00990
gene id: 1423720:LA20249_RS00990
uniprot id: A0A2K9HE80
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS02175
gene id: 1423720:LA20249_RS02175
uniprot id: A0A2K9HH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS02825
gene id: 1423720:LA20249_RS02825
uniprot id: A0A2K9HPD0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1423720:LA20249 RS11315
gene id: 1423720:LA20249_RS11315
uniprot id: A0A2K9HQF3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1423720:LA20249 RS10695
gene id: 1423720:LA20249_RS10695
uniprot id: A0A2K9HJ99
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS04230
gene id: 1423720:LA20249_RS04230
uniprot id: A0A2K9HI38
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1423720:LA20249 RS04420
gene id: 1423720:LA20249_RS04420
uniprot id: A0A2K9HG03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1423720:LA20249 RS08995
gene id: 1423720:LA20249_RS08995
uniprot id: A0A2K9HKH7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423720:LA20249 RS10260
gene id: 1423720:LA20249_RS10260
uniprot id: A0A2K9HJ15
names: Similarity
messages: Belongs to the PemK/MazF family.

1423720:LA20249 RS00750
gene id: 1423720:LA20249_RS00750
uniprot id: A0A2K9HEM0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423720:LA20249 RS10820
gene id: 1423720:LA20249_RS10820
uniprot id: A0A2K9HN10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS08110
gene id: 1423720:LA20249_RS08110
uniprot id: A0A2K9HHW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1423720:LA20249 RS01170
gene id: 1423720:LA20249_RS01170
uniprot id: A0A2K9HEB0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1423720:LA20249 RS04170
gene id: 1423720:LA20249_RS04170
uniprot id: A0A2K9HIA5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1423720:LA20249 RS07975
gene id: 1423720:LA20249_RS07975
uniprot id: A0A2K9HK68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1423720:LA20249 RS09560
gene id: 1423720:LA20249_RS09560
uniprot id: A0A2K9HMJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1423720:LA20249 RS08100
gene id: 1423720:LA20249_RS08100
uniprot id: A0A2K9HQY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1423720:LA20249 RS00915
gene id: 1423720:LA20249_RS00915
uniprot id: A0A2K9HGP3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1423720:LA20249 RS05610
gene id: 1423720:LA20249_RS05610
uniprot id: A0A2K9HGK3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1423720:LA20249 RS02625
gene id: 1423720:LA20249_RS02625
uniprot id: A0A2K9HHI7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1423720:LA20249 RS06415
gene id: 1423720:LA20249_RS06415
uniprot id: A0A2K9HJE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS01675
gene id: 1423720:LA20249_RS01675
uniprot id: A0A2K9HM20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1423720:LA20249 RS02505
gene id: 1423720:LA20249_RS02505
uniprot id: A0A2K9HH77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1423720:LA20249 RS04005
gene id: 1423720:LA20249_RS04005
uniprot id: A0A2K9HKJ4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1423720:LA20249 RS00210
gene id: 1423720:LA20249_RS00210
uniprot id: A0A2K9HGF3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1423720:LA20249 RS04240
gene id: 1423720:LA20249_RS04240
uniprot id: A0A2K9HGE7
names: Similarity
messages: Belongs to the HesB/IscA family.

1423720:LA20249 RS04995
gene id: 1423720:LA20249_RS04995
uniprot id: A0A2K9HG98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1423720:LA20249 RS02385
gene id: 1423720:LA20249_RS02385
uniprot id: A0A2K9HMA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1423720:LA20249 RS10385
gene id: 1423720:LA20249_RS10385
uniprot id: A0A2K9HKW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS08795
gene id: 1423720:LA20249_RS08795
uniprot id: A0A2K9HJZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1423720:LA20249 RS05885
gene id: 1423720:LA20249_RS05885
uniprot id: A0A2K9HQ94
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1423720:LA20249 RS10570
gene id: 1423720:LA20249_RS10570
uniprot id: A0A2K9HL21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1423720:LA20249 RS10595
gene id: 1423720:LA20249_RS10595
uniprot id: A0A2K9HRM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1423720:LA20249 RS04080
gene id: 1423720:LA20249_RS04080
uniprot id: A0A2K9HFU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1423720:LA20249 RS08165
gene id: 1423720:LA20249_RS08165
uniprot id: A0A2K9HM35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1423720:LA20249 RS10550
gene id: 1423720:LA20249_RS10550
uniprot id: A0A2K9HPW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1423720:LA20249 RS04105
gene id: 1423720:LA20249_RS04105
uniprot id: A0A2K9HFT8
names: Similarity
messages: Belongs to the TlyA family.

1423720:LA20249 RS11185
gene id: 1423720:LA20249_RS11185
uniprot id: A0A2K9HQ39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1423720:LA20249 RS02170
gene id: 1423720:LA20249_RS02170
uniprot id: A0A2K9HJX4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1423720:LA20249 RS07140
gene id: 1423720:LA20249_RS07140
uniprot id: A0A2K9HHE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS10470
gene id: 1423720:LA20249_RS10470
uniprot id: A0A2K9HJM3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1423720:LA20249 RS08745
gene id: 1423720:LA20249_RS08745
uniprot id: A0A2K9HI79
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1423720:LA20249 RS07655
gene id: 1423720:LA20249_RS07655
uniprot id: A0A2K9HLW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1423720:LA20249 RS03275
gene id: 1423720:LA20249_RS03275
uniprot id: A0A2K9HKC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS06320
gene id: 1423720:LA20249_RS06320
uniprot id: A0A2K9HGZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1423720:LA20249 RS10435
gene id: 1423720:LA20249_RS10435
uniprot id: A0A2K9HKX2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1423720:LA20249 RS00105
gene id: 1423720:LA20249_RS00105
uniprot id: A0A2N9YJP4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1423720:LA20249 RS03200
gene id: 1423720:LA20249_RS03200
uniprot id: A0A2K9HFC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1423720:LA20249 RS01160
gene id: 1423720:LA20249_RS01160
uniprot id: A0A2K9HEB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1423720:LA20249 RS03895
gene id: 1423720:LA20249_RS03895
uniprot id: A0A2K9HI58
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS07950
gene id: 1423720:LA20249_RS07950
uniprot id: A0A2K9HQX3
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS09725
gene id: 1423720:LA20249_RS09725
uniprot id: A0A2K9HKL8
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS07035
gene id: 1423720:LA20249_RS07035
uniprot id: A0A2K9HHC1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1423720:LA20249 RS04525
gene id: 1423720:LA20249_RS04525
uniprot id: A0A2K9HPW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1423720:LA20249 RS09950
gene id: 1423720:LA20249_RS09950
uniprot id: A0A2K9HIW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1423720:LA20249 RS04100
gene id: 1423720:LA20249_RS04100
uniprot id: A0A2K9HMU6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1423720:LA20249 RS07830
gene id: 1423720:LA20249_RS07830
uniprot id: A0A2K9HHS8
names: Similarity
messages: Belongs to the transketolase family.

1423720:LA20249 RS06270
gene id: 1423720:LA20249_RS06270
uniprot id: A0A2K9HGY4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1423720:LA20249 RS01340
gene id: 1423720:LA20249_RS01340
uniprot id: A0A2K9HRV4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423720:LA20249 RS06930
gene id: 1423720:LA20249_RS06930
uniprot id: A0A2K9HHC0
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1423720:LA20249 RS06055
gene id: 1423720:LA20249_RS06055
uniprot id: A0A2K9HQD4
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1423720:LA20249 RS09280
gene id: 1423720:LA20249_RS09280
uniprot id: A0A2K9HIJ6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1423720:LA20249 RS05015
gene id: 1423720:LA20249_RS05015
uniprot id: A0A2K9HKX1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1423720:LA20249 RS08815
gene id: 1423720:LA20249_RS08815
uniprot id: A0A2K9HI91
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS05190
gene id: 1423720:LA20249_RS05190
uniprot id: A0A2K9HGE3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS05710
gene id: 1423720:LA20249_RS05710
uniprot id: A0A2K9HGL7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1423720:LA20249 RS03775
gene id: 1423720:LA20249_RS03775
uniprot id: A0A2K9HHV5
names: Similarity
messages: Belongs to the ribF family.

1423720:LA20249 RS09955
gene id: 1423720:LA20249_RS09955
uniprot id: A0A2K9HIV5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1423720:LA20249 RS07895
gene id: 1423720:LA20249_RS07895
uniprot id: A0A2K9HQW8
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS03215
gene id: 1423720:LA20249_RS03215
uniprot id: A0A2K9HFC1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1423720:LA20249 RS09700
gene id: 1423720:LA20249_RS09700
uniprot id: A0A2K9HRD7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423720:LA20249 RS10155
gene id: 1423720:LA20249_RS10155
uniprot id: A0A2K9HJ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1423720:LA20249 RS10180
gene id: 1423720:LA20249_RS10180
uniprot id: A0A2K9HMS3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS10995
gene id: 1423720:LA20249_RS10995
uniprot id: A0A2K9HJX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1423720:LA20249 RS04835
gene id: 1423720:LA20249_RS04835
uniprot id: A0A2K9HG58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1423720:LA20249 RS10560
gene id: 1423720:LA20249_RS10560
uniprot id: A0A2K9HMW7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1423720:LA20249 RS11040
gene id: 1423720:LA20249_RS11040
uniprot id: A0A2K9HL93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1423720:LA20249 RS08310
gene id: 1423720:LA20249_RS08310
uniprot id: A0A2K9HI00
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1423720:LA20249 RS08300
gene id: 1423720:LA20249_RS08300
uniprot id: A0A2K9HI17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1423720:LA20249 RS04965
gene id: 1423720:LA20249_RS04965
uniprot id: A0A2K9HKW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS09510
gene id: 1423720:LA20249_RS09510
uniprot id: A0A2K9HJ39
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1423720:LA20249 RS10865
gene id: 1423720:LA20249_RS10865
uniprot id: A0A2K9HQ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS07335
gene id: 1423720:LA20249_RS07335
uniprot id: A0A2K9HJV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1423720:LA20249 RS02990
gene id: 1423720:LA20249_RS02990
uniprot id: A0A2K9HPE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS02500
gene id: 1423720:LA20249_RS02500
uniprot id: A0A2K9HK33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1423720:LA20249 RS01400
gene id: 1423720:LA20249_RS01400
uniprot id: A0A2K9HEE5
names: Similarity
messages: Belongs to the UPF0177 family.

1423720:LA20249 RS05605
gene id: 1423720:LA20249_RS05605
uniprot id: A0A2K9HNC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1423720:LA20249 RS03565
gene id: 1423720:LA20249_RS03565
uniprot id: A0A2K9HHZ5
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1423720:LA20249 RS06745
gene id: 1423720:LA20249_RS06745
uniprot id: A0A2K9HJE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS03160
gene id: 1423720:LA20249_RS03160
uniprot id: A0A2K9HMJ3
names: Similarity
messages: Belongs to the threonine synthase family.

1423720:LA20249 RS09070
gene id: 1423720:LA20249_RS09070
uniprot id: A0A2K9HID9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1423720:LA20249 RS03185
gene id: 1423720:LA20249_RS03185
uniprot id: A0A2K9HFV5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Homohexamer.

1423720:LA20249 RS08675
gene id: 1423720:LA20249_RS08675
uniprot id: A0A2K9HKE5
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS06295
gene id: 1423720:LA20249_RS06295
uniprot id: A0A2K9HJ71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1423720:LA20249 RS07090
gene id: 1423720:LA20249_RS07090
uniprot id: A0A2K9HHC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1423720:LA20249 RS04210
gene id: 1423720:LA20249_RS04210
uniprot id: A0A2K9HMW4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1423720:LA20249 RS07800
gene id: 1423720:LA20249_RS07800
uniprot id: A0A2K9HP17
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS01485
gene id: 1423720:LA20249_RS01485
uniprot id: A0A2K9HGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1423720:LA20249 RS11285
gene id: 1423720:LA20249_RS11285
uniprot id: A0A2K9HLQ7
names: Similarity
messages: Belongs to the zeta toxin family.

1423720:LA20249 RS00710
gene id: 1423720:LA20249_RS00710
uniprot id: A0A2K9HE31
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS04250
gene id: 1423720:LA20249_RS04250
uniprot id: A0A2K9HFX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1423720:LA20249 RS10625
gene id: 1423720:LA20249_RS10625
uniprot id: A0A2K9HJQ2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1423720:LA20249 RS08575
gene id: 1423720:LA20249_RS08575
uniprot id: A0A2K9HIM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS11025
gene id: 1423720:LA20249_RS11025
uniprot id: A0A2K9HJG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1423720:LA20249 RS11065
gene id: 1423720:LA20249_RS11065
uniprot id: A0A2K9HRS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1423720:LA20249 RS02045
gene id: 1423720:LA20249_RS02045
uniprot id: A0A2K9HER1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423720:LA20249 RS10545
gene id: 1423720:LA20249_RS10545
uniprot id: A0A2K9HRL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1423720:LA20249 RS05035
gene id: 1423720:LA20249_RS05035
uniprot id: A0A2K9HGB2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1423720:LA20249 RS01205
gene id: 1423720:LA20249_RS01205
uniprot id: A0A2K9HGU1
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS05865
gene id: 1423720:LA20249_RS05865
uniprot id: A0A2K9HGR0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1423720:LA20249 RS05200
gene id: 1423720:LA20249_RS05200
uniprot id: A0A2K9HGE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1423720:LA20249 RS02510
gene id: 1423720:LA20249_RS02510
uniprot id: A0A2K9HHG8
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

1423720:LA20249 RS02260
gene id: 1423720:LA20249_RS02260
uniprot id: A0A2K9HP74
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1423720:LA20249 RS01315
gene id: 1423720:LA20249_RS01315
uniprot id: A0A2K9HGV8
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS03915
gene id: 1423720:LA20249_RS03915
uniprot id: A0A2K9HFQ6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1423720:LA20249 RS09145
gene id: 1423720:LA20249_RS09145
uniprot id: A0A2K9HMF3
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1423720:LA20249 RS02145
gene id: 1423720:LA20249_RS02145
uniprot id: A0A2K9HEU0
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1423720:LA20249 RS04030
gene id: 1423720:LA20249_RS04030
uniprot id: A0A2K9HFT2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1423720:LA20249 RS02540
gene id: 1423720:LA20249_RS02540
uniprot id: A0A2K9HPA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1423720:LA20249 RS05315
gene id: 1423720:LA20249_RS05315
uniprot id: A0A2K9HGG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

1423720:LA20249 RS10300
gene id: 1423720:LA20249_RS10300
uniprot id: A0A2K9HJ49
names: Similarity
messages: Belongs to the TPP enzyme family.

1423720:LA20249 RS09640
gene id: 1423720:LA20249_RS09640
uniprot id: A0A2K9HIP2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1423720:LA20249 RS03805
gene id: 1423720:LA20249_RS03805
uniprot id: A0A2K9HFN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1423720:LA20249 RS00815
gene id: 1423720:LA20249_RS00815
uniprot id: A0A2K9HE52
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1423720:LA20249 RS04405
gene id: 1423720:LA20249_RS04405
uniprot id: A0A2K9HGH6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1423720:LA20249 RS06255
gene id: 1423720:LA20249_RS06255
uniprot id: A0A2K9HHE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

1423720:LA20249 RS03135
gene id: 1423720:LA20249_RS03135
uniprot id: A0A2K9HFU3
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS07315
gene id: 1423720:LA20249_RS07315
uniprot id: A0A2K9HNW1
names: Similarity
messages: Belongs to the FBPase class 3 family.

1423720:LA20249 RS02550
gene id: 1423720:LA20249_RS02550
uniprot id: A0A2K9HF01
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423720:LA20249 RS08760
gene id: 1423720:LA20249_RS08760
uniprot id: A0A2K9HI82
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1423720:LA20249 RS06030
gene id: 1423720:LA20249_RS06030
uniprot id: A0A2K9HHA4
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1423720:LA20249 RS10505
gene id: 1423720:LA20249_RS10505
uniprot id: A0A2K9HMV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1423720:LA20249 RS02300
gene id: 1423720:LA20249_RS02300
uniprot id: A0A2K9HEW9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1423720:LA20249 RS11170
gene id: 1423720:LA20249_RS11170
uniprot id: A0A2K9HJJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1423720:LA20249 RS08415
gene id: 1423720:LA20249_RS08415
uniprot id: A0A2K9HI19
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS08120
gene id: 1423720:LA20249_RS08120
uniprot id: A0A2K9HK45
names: Similarity
messages: Belongs to the ThiD family.

1423720:LA20249 RS03695
gene id: 1423720:LA20249_RS03695
uniprot id: A0A2K9HFL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1423720:LA20249 RS00085
gene id: 1423720:LA20249_RS00085
uniprot id: A0A2N9YJR8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS09995
gene id: 1423720:LA20249_RS09995
uniprot id: A0A2K9HIY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1423720:LA20249 RS07270
gene id: 1423720:LA20249_RS07270
uniprot id: A0A2K9HLS7
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS10660
gene id: 1423720:LA20249_RS10660
uniprot id: A0A2K9HMY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS09565
gene id: 1423720:LA20249_RS09565
uniprot id: A0A2K9HKJ6
names: Similarity
messages: Belongs to the SecB family.

1423720:LA20249 RS02165
gene id: 1423720:LA20249_RS02165
uniprot id: A0A2K9HET1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423720:LA20249 RS10615
gene id: 1423720:LA20249_RS10615
uniprot id: A0A2K9HKZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1423720:LA20249 RS05905
gene id: 1423720:LA20249_RS05905
uniprot id: A0A2K9HJ61
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1423720:LA20249 RS05820
gene id: 1423720:LA20249_RS05820
uniprot id: A0A2K9HNE9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423720:LA20249 RS08305
gene id: 1423720:LA20249_RS08305
uniprot id: A0A2K9HI07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1423720:LA20249 RS10775
gene id: 1423720:LA20249_RS10775
uniprot id: A0A2K9HL20
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1423720:LA20249 RS01445
gene id: 1423720:LA20249_RS01445
uniprot id: A0A2K9HEG0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1423720:LA20249 RS02370
gene id: 1423720:LA20249_RS02370
uniprot id: A0A2K9HEX8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1423720:LA20249 RS06720
gene id: 1423720:LA20249_RS06720
uniprot id: A0A2K9HH62
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS00680
gene id: 1423720:LA20249_RS00680
uniprot id: A0A2K9HJ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1423720:LA20249 RS04020
gene id: 1423720:LA20249_RS04020
uniprot id: A0A2K9HI77
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1423720:LA20249 RS07650
gene id: 1423720:LA20249_RS07650
uniprot id: A0A2K9HHN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1423720:LA20249 RS05110
gene id: 1423720:LA20249_RS05110
uniprot id: A0A2K9HGA7
names: Similarity
messages: Belongs to the IMPACT family.

1423720:LA20249 RS05400
gene id: 1423720:LA20249_RS05400
uniprot id: A0A2K9HGG1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS03245
gene id: 1423720:LA20249_RS03245
uniprot id: A0A2K9HFE1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1423720:LA20249 RS00955
gene id: 1423720:LA20249_RS00955
uniprot id: A0A2K9HJB8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1423720:LA20249 RS03255
gene id: 1423720:LA20249_RS03255
uniprot id: A0A2K9HFD7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1423720:LA20249 RS01430
gene id: 1423720:LA20249_RS01430
uniprot id: A0A2K9HGX7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1423720:LA20249 RS10655
gene id: 1423720:LA20249_RS10655
uniprot id: A0A2K9HJ94
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1423720:LA20249 RS01875
gene id: 1423720:LA20249_RS01875
uniprot id: A0A2K9HEM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1423720:LA20249 RS02490
gene id: 1423720:LA20249_RS02490
uniprot id: A0A2K9HMB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1423720:LA20249 RS04090
gene id: 1423720:LA20249_RS04090
uniprot id: A0A2K9HFT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1423720:LA20249 RS09395
gene id: 1423720:LA20249_RS09395
uniprot id: A0A2K9HIJ8
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS03760
gene id: 1423720:LA20249_RS03760
uniprot id: A0A2K9HMQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1423720:LA20249 RS05680
gene id: 1423720:LA20249_RS05680
uniprot id: A0A2K9HH38
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1423720:LA20249 RS00645
gene id: 1423720:LA20249_RS00645
uniprot id: A0A2K9HE25
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS01555
gene id: 1423720:LA20249_RS01555
uniprot id: A0A2K9HEI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1423720:LA20249 RS02835
gene id: 1423720:LA20249_RS02835
uniprot id: A0A2K9HF53
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423720:LA20249 RS08365
gene id: 1423720:LA20249_RS08365
uniprot id: A0A2K9HI09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1423720:LA20249 RS01335
gene id: 1423720:LA20249_RS01335
uniprot id: A0A2K9HED5
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS05730
gene id: 1423720:LA20249_RS05730
uniprot id: A0A2K9HJ27
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1423720:LA20249 RS02805
gene id: 1423720:LA20249_RS02805
uniprot id: A0A2K9HF49
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1423720:LA20249 RS03630
gene id: 1423720:LA20249_RS03630
uniprot id: A0A2K9HFK7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423720:LA20249 RS04740
gene id: 1423720:LA20249_RS04740
uniprot id: A0A2K9HG48
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1423720:LA20249 RS06645
gene id: 1423720:LA20249_RS06645
uniprot id: A0A2K9HJI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1423720:LA20249 RS00785
gene id: 1423720:LA20249_RS00785
uniprot id: A0A2K9HE43
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS04330
gene id: 1423720:LA20249_RS04330
uniprot id: A0A2K9HKN4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1423720:LA20249 RS03990
gene id: 1423720:LA20249_RS03990
uniprot id: A0A2K9HFR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1423720:LA20249 RS01455
gene id: 1423720:LA20249_RS01455
uniprot id: A0A2K9HNY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1423720:LA20249 RS04235
gene id: 1423720:LA20249_RS04235
uniprot id: A0A2K9HIB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS11035
gene id: 1423720:LA20249_RS11035
uniprot id: A0A2K9HL62
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1423720:LA20249 RS11735
gene id: 1423720:LA20249_RS11735
uniprot id: A0A2K9HKX6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1423720:LA20249 RS11095
gene id: 1423720:LA20249_RS11095
uniprot id: A0A2K9HL98
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1423720:LA20249 RS08765
gene id: 1423720:LA20249_RS08765
uniprot id: A0A2K9HMB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1423720:LA20249 RS08380
gene id: 1423720:LA20249_RS08380
uniprot id: A0A2K9HI14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1423720:LA20249 RS10170
gene id: 1423720:LA20249_RS10170
uniprot id: A0A2K9HPS5
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1423720:LA20249 RS11420
gene id: 1423720:LA20249_RS11420
uniprot id: A0A2K9HK12
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1423720:LA20249 RS10745
gene id: 1423720:LA20249_RS10745
uniprot id: A0A2K9HJA8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1423720:LA20249 RS11045
gene id: 1423720:LA20249_RS11045
uniprot id: A0A2K9HJY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1423720:LA20249 RS08330
gene id: 1423720:LA20249_RS08330
uniprot id: A0A2K9HI04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1423720:LA20249 RS00065
gene id: 1423720:LA20249_RS00065
uniprot id: A0A2K9HL92
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1423720:LA20249 RS05890
gene id: 1423720:LA20249_RS05890
uniprot id: A0A2K9HGQ9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1423720:LA20249 RS04380
gene id: 1423720:LA20249_RS04380
uniprot id: A0A2K9HFY5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS11930
gene id: 1423720:LA20249_RS11930
uniprot id: A0A2K9HKE7
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1423720:LA20249 RS08420
gene id: 1423720:LA20249_RS08420
uniprot id: A0A2K9HR17
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS10425
gene id: 1423720:LA20249_RS10425
uniprot id: A0A2K9HJ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1423720:LA20249 RS02220
gene id: 1423720:LA20249_RS02220
uniprot id: A0A2K9HJY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0213 family.
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1423720:LA20249 RS04260
gene id: 1423720:LA20249_RS04260
uniprot id: A0A2K9HPT8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1423720:LA20249 RS01905
gene id: 1423720:LA20249_RS01905
uniprot id: A0A2K9HH60
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1423720:LA20249 RS02700
gene id: 1423720:LA20249_RS02700
uniprot id: A0A2K9HF27
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1423720:LA20249 RS02580
gene id: 1423720:LA20249_RS02580
uniprot id: A0A2K9HFJ7
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS09745
gene id: 1423720:LA20249_RS09745
uniprot id: A0A2K9HIS4
names: Similarity
messages: Belongs to the XFP family.

1423720:LA20249 RS10600
gene id: 1423720:LA20249_RS10600
uniprot id: A0A2K9HPX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1423720:LA20249 RS01650
gene id: 1423720:LA20249_RS01650
uniprot id: A0A2K9HEJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1423720:LA20249 RS00070
gene id: 1423720:LA20249_RS00070
uniprot id: A0A2N9YJM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1423720:LA20249 RS01190
gene id: 1423720:LA20249_RS01190
uniprot id: A0A2K9HJM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS08560
gene id: 1423720:LA20249_RS08560
uniprot id: A0A2K9HM80
names: Function
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.

1423720:LA20249 RS07095
gene id: 1423720:LA20249_RS07095
uniprot id: A0A2K9HQN9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423720:LA20249 RS11925
gene id: 1423720:LA20249_RS11925
uniprot id: A0A2K9HFH6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1423720:LA20249 RS01995
gene id: 1423720:LA20249_RS01995
uniprot id: A0A2K9HJU2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423720:LA20249 RS10830
gene id: 1423720:LA20249_RS10830
uniprot id: A0A2K9HL64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1423720:LA20249 RS04225
gene id: 1423720:LA20249_RS04225
uniprot id: A0A2K9HKL9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1423720:LA20249 RS06245
gene id: 1423720:LA20249_RS06245
uniprot id: A0A2K9HJ65
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1423720:LA20249 RS06660
gene id: 1423720:LA20249_RS06660
uniprot id: A0A2K9HH54
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423720:LA20249 RS09735
gene id: 1423720:LA20249_RS09735
uniprot id: A0A2K9HJ74
names: Similarity
messages: Belongs to the peptidase C59 family.

1423720:LA20249 RS06405
gene id: 1423720:LA20249_RS06405
uniprot id: A0A2K9HLG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS06715
gene id: 1423720:LA20249_RS06715
uniprot id: A0A2K9HH64
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS07245
gene id: 1423720:LA20249_RS07245
uniprot id: A0A2K9HHF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1423720:LA20249 RS05435
gene id: 1423720:LA20249_RS05435
uniprot id: A0A2K9HGI2
names: Similarity
messages: Belongs to the CitG/MdcB family.

1423720:LA20249 RS02360
gene id: 1423720:LA20249_RS02360
uniprot id: A0A2K9HEX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1423720:LA20249 RS08320
gene id: 1423720:LA20249_RS08320
uniprot id: A0A2K9HR07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1423720:LA20249 RS10890
gene id: 1423720:LA20249_RS10890
uniprot id: A0A2K9HJV6
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS03320
gene id: 1423720:LA20249_RS03320
uniprot id: A0A2K9HFE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1423720:LA20249 RS09905
gene id: 1423720:LA20249_RS09905
uniprot id: A0A2K9HIU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS09655
gene id: 1423720:LA20249_RS09655
uniprot id: A0A2K9HPL9
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS03505
gene id: 1423720:LA20249_RS03505
uniprot id: A0A2K9HHY5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423720:LA20249 RS08140
gene id: 1423720:LA20249_RS08140
uniprot id: A0A2K9HHX7
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS01980
gene id: 1423720:LA20249_RS01980
uniprot id: A0A2K9HP45
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423720:LA20249 RS08355
gene id: 1423720:LA20249_RS08355
uniprot id: A0A2K9HI27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1423720:LA20249 RS02760
gene id: 1423720:LA20249_RS02760
uniprot id: A0A2K9HPC4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423720:LA20249 RS03340
gene id: 1423720:LA20249_RS03340
uniprot id: A0A2K9HFY4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1423720:LA20249 RS10585
gene id: 1423720:LA20249_RS10585
uniprot id: A0A2K9HJ83
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1423720:LA20249 RS06975
gene id: 1423720:LA20249_RS06975
uniprot id: A0A2K9HHS2
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS00590
gene id: 1423720:LA20249_RS00590
uniprot id: A0A2K9HEJ2
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1423720:LA20249 RS08130
gene id: 1423720:LA20249_RS08130
uniprot id: A0A2K9HIE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS01010
gene id: 1423720:LA20249_RS01010
uniprot id: A0A2K9HK50
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1423720:LA20249 RS06775
gene id: 1423720:LA20249_RS06775
uniprot id: A0A2K9HQL0
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS01045
gene id: 1423720:LA20249_RS01045
uniprot id: A0A2K9HER7
names: Similarity
messages: Belongs to the FGGY kinase family.

1423720:LA20249 RS04975
gene id: 1423720:LA20249_RS04975
uniprot id: A0A2K9HIN6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1423720:LA20249 RS03220
gene id: 1423720:LA20249_RS03220
uniprot id: A0A2K9HKB8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1423720:LA20249 RS04075
gene id: 1423720:LA20249_RS04075
uniprot id: A0A2K9HGB3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1423720:LA20249 RS01345
gene id: 1423720:LA20249_RS01345
uniprot id: A0A2K9HNX0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS04840
gene id: 1423720:LA20249_RS04840
uniprot id: A0A2K9HKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1423720:LA20249 RS03885
gene id: 1423720:LA20249_RS03885
uniprot id: A0A2K9HKI5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS03655
gene id: 1423720:LA20249_RS03655
uniprot id: A0A2K9HMP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1423720:LA20249 RS07410
gene id: 1423720:LA20249_RS07410
uniprot id: A0A2K9HHK1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1423720:LA20249 RS04140
gene id: 1423720:LA20249_RS04140
uniprot id: A0A2K9HFU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1423720:LA20249 RS00835
gene id: 1423720:LA20249_RS00835
uniprot id: A0A2K9HE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS03850
gene id: 1423720:LA20249_RS03850
uniprot id: A0A2K9HFP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1423720:LA20249 RS00580
gene id: 1423720:LA20249_RS00580
uniprot id: A0A2K9HG94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1423720:LA20249 RS03065
gene id: 1423720:LA20249_RS03065
uniprot id: A0A2K9HKA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1423720:LA20249 RS11380
gene id: 1423720:LA20249_RS11380
uniprot id: A0A2K9HK29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1423720:LA20249 RS00225
gene id: 1423720:LA20249_RS00225
uniprot id: A0A2K9HDX4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

1423720:LA20249 RS04400
gene id: 1423720:LA20249_RS04400
uniprot id: A0A2K9HQ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1423720:LA20249 RS06795
gene id: 1423720:LA20249_RS06795
uniprot id: A0A2K9HLL5
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS04145
gene id: 1423720:LA20249_RS04145
uniprot id: A0A2K9HPS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1423720:LA20249 RS09335
gene id: 1423720:LA20249_RS09335
uniprot id: A0A2K9HII7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423720:LA20249 RS00485
gene id: 1423720:LA20249_RS00485
uniprot id: A0A2K9HDZ2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1423720:LA20249 RS07725
gene id: 1423720:LA20249_RS07725
uniprot id: A0A2K9HHQ8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1423720:LA20249 RS02905
gene id: 1423720:LA20249_RS02905
uniprot id: A0A2K9HHE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1423720:LA20249 RS03265
gene id: 1423720:LA20249_RS03265
uniprot id: A0A2K9HMK7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1423720:LA20249 RS01645
gene id: 1423720:LA20249_RS01645
uniprot id: A0A2K9HF33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS05030
gene id: 1423720:LA20249_RS05030
uniprot id: A0A2K9HGR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1423720:LA20249 RS00135
gene id: 1423720:LA20249_RS00135
uniprot id: A0A2N9YJP9
names: Similarity
messages: Belongs to the thioredoxin family.

1423720:LA20249 RS03750
gene id: 1423720:LA20249_RS03750
uniprot id: A0A2K9HFM7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1423720:LA20249 RS03845
gene id: 1423720:LA20249_RS03845
uniprot id: A0A2K9HG73
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS04155
gene id: 1423720:LA20249_RS04155
uniprot id: A0A2K9HFU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1423720:LA20249 RS06675
gene id: 1423720:LA20249_RS06675
uniprot id: A0A2K9HNP8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1423720:LA20249 RS03935
gene id: 1423720:LA20249_RS03935
uniprot id: A0A2K9HKJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1423720:LA20249 RS10520
gene id: 1423720:LA20249_RS10520
uniprot id: A0A2K9HL16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1423720:LA20249 RS10825
gene id: 1423720:LA20249_RS10825
uniprot id: A0A2K9HL30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS03155
gene id: 1423720:LA20249_RS03155
uniprot id: A0A2K9HPG7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1423720:LA20249 RS09315
gene id: 1423720:LA20249_RS09315
uniprot id: A0A2K9HKK6
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS02265
gene id: 1423720:LA20249_RS02265
uniprot id: A0A2K9HM88
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1423720:LA20249 RS06315
gene id: 1423720:LA20249_RS06315
uniprot id: A0A2K9HH17
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1423720:LA20249 RS01705
gene id: 1423720:LA20249_RS01705
uniprot id: A0A2K9HEK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS09275
gene id: 1423720:LA20249_RS09275
uniprot id: A0A2K9HIK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS00720
gene id: 1423720:LA20249_RS00720
uniprot id: A0A2K9HNQ6
names: Subcellular Location Annotation
messages: Cell membrane

1423720:LA20249 RS05625
gene id: 1423720:LA20249_RS05625
uniprot id: A0A2K9HJ07
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS04055
gene id: 1423720:LA20249_RS04055
uniprot id: A0A2K9HFS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1423720:LA20249 RS02780
gene id: 1423720:LA20249_RS02780
uniprot id: A0A2K9HF43
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1423720:LA20249 RS10905
gene id: 1423720:LA20249_RS10905
uniprot id: A0A2K9HJD9
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS06910
gene id: 1423720:LA20249_RS06910
uniprot id: A0A2K9HLN0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1423720:LA20249 RS03140
gene id: 1423720:LA20249_RS03140
uniprot id: A0A2K9HFB2
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS10295
gene id: 1423720:LA20249_RS10295
uniprot id: A0A2K9HJJ3
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1423720:LA20249 RS03205
gene id: 1423720:LA20249_RS03205
uniprot id: A0A2K9HPG9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1423720:LA20249 RS03365
gene id: 1423720:LA20249_RS03365
uniprot id: A0A2K9HMM0
names: Subcellular Location Annotation
messages: cell wall

1423720:LA20249 RS00435
gene id: 1423720:LA20249_RS00435
uniprot id: A0A2K9HNN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1423720:LA20249 RS04685
gene id: 1423720:LA20249_RS04685
uniprot id: A0A2K9HKT1
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1423720:LA20249 RS09360
gene id: 1423720:LA20249_RS09360
uniprot id: A0A2K9HMH8
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS03960
gene id: 1423720:LA20249_RS03960
uniprot id: A0A2K9HFS7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1423720:LA20249 RS08905
gene id: 1423720:LA20249_RS08905
uniprot id: A0A2K9HIB1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1423720:LA20249 RS07610
gene id: 1423720:LA20249_RS07610
uniprot id: A0A2K9HJV3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS04050
gene id: 1423720:LA20249_RS04050
uniprot id: A0A2K9HMU0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1423720:LA20249 RS09780
gene id: 1423720:LA20249_RS09780
uniprot id: A0A2K9HKR3
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS09480
gene id: 1423720:LA20249_RS09480
uniprot id: A0A2K9HRC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS01420
gene id: 1423720:LA20249_RS01420
uniprot id: A0A2K9HJJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1423720:LA20249 RS06635
gene id: 1423720:LA20249_RS06635
uniprot id: A0A2K9HLJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
messages: Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1423720:LA20249 RS10445
gene id: 1423720:LA20249_RS10445
uniprot id: A0A2K9HS07
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1423720:LA20249 RS02075
gene id: 1423720:LA20249_RS02075
uniprot id: A0A2K9HES6
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1423720:LA20249 RS03310
gene id: 1423720:LA20249_RS03310
uniprot id: A0A2K9HPI4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1423720:LA20249 RS08290
gene id: 1423720:LA20249_RS08290
uniprot id: A0A2K9HKA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1423720:LA20249 RS10605
gene id: 1423720:LA20249_RS10605
uniprot id: A0A2K9HJ84
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1423720:LA20249 RS03675
gene id: 1423720:LA20249_RS03675
uniprot id: A0A2K9HI22
names: Similarity
messages: Belongs to the universal stress protein A family.

1423720:LA20249 RS10735
gene id: 1423720:LA20249_RS10735
uniprot id: A0A2K9HJD1
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS05700
gene id: 1423720:LA20249_RS05700
uniprot id: A0A2K9HQ93
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1423720:LA20249 RS09805
gene id: 1423720:LA20249_RS09805
uniprot id: A0A2K9HRE6
names: Similarity
messages: Belongs to the universal stress protein A family.

1423720:LA20249 RS01670
gene id: 1423720:LA20249_RS01670
uniprot id: A0A2K9HP07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1423720:LA20249 RS09650
gene id: 1423720:LA20249_RS09650
uniprot id: A0A2K9HRD3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1423720:LA20249 RS05515
gene id: 1423720:LA20249_RS05515
uniprot id: A0A2K9HIR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-serine, forming acetyl-L-serine.

1423720:LA20249 RS03860
gene id: 1423720:LA20249_RS03860
uniprot id: A0A2K9HFP7
names: Similarity
messages: Belongs to the UPF0213 family.

1423720:LA20249 RS02025
gene id: 1423720:LA20249_RS02025
uniprot id: A0A2K9HES0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1423720:LA20249 RS04440
gene id: 1423720:LA20249_RS04440
uniprot id: A0A2K9HKP9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1423720:LA20249 RS01885
gene id: 1423720:LA20249_RS01885
uniprot id: A0A2K9HM41
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1423720:LA20249 RS08155
gene id: 1423720:LA20249_RS08155
uniprot id: A0A2K9HP57
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1423720:LA20249 RS05620
gene id: 1423720:LA20249_RS05620
uniprot id: A0A2K9HIT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1423720:LA20249 RS04040
gene id: 1423720:LA20249_RS04040
uniprot id: A0A2K9HFS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1423720:LA20249 RS03965
gene id: 1423720:LA20249_RS03965
uniprot id: A0A2K9HFR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1423720:LA20249 RS08750
gene id: 1423720:LA20249_RS08750
uniprot id: A0A2K9HR52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cell envelope
messages: Releases the N-terminal proline from various substrates.

1423720:LA20249 RS09615
gene id: 1423720:LA20249_RS09615
uniprot id: A0A2K9HKK2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1423720:LA20249 RS06760
gene id: 1423720:LA20249_RS06760
uniprot id: A0A2K9HH90
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS02750
gene id: 1423720:LA20249_RS02750
uniprot id: A0A2K9HF36
names: Similarity
messages: Belongs to the EamA transporter family.

1423720:LA20249 RS10555
gene id: 1423720:LA20249_RS10555
uniprot id: A0A2K9HJ75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1423720:LA20249 RS02595
gene id: 1423720:LA20249_RS02595
uniprot id: A0A2K9HF07
names: Similarity
messages: Belongs to the LOG family.

1423720:LA20249 RS10525
gene id: 1423720:LA20249_RS10525
uniprot id: A0A2K9HJM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1423720:LA20249 RS07345
gene id: 1423720:LA20249_RS07345
uniprot id: A0A2K9HHJ5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1423720:LA20249 RS09125
gene id: 1423720:LA20249_RS09125
uniprot id: A0A2K9HIE8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423720:LA20249 RS07355
gene id: 1423720:LA20249_RS07355
uniprot id: A0A2K9HHH5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1423720:LA20249 RS07390
gene id: 1423720:LA20249_RS07390
uniprot id: A0A2K9HJW6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS12000
gene id: 1423720:LA20249_RS12000
uniprot id: A0A2K9HIZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1423720:LA20249 RS03325
gene id: 1423720:LA20249_RS03325
uniprot id: A0A2K9HKD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1423720:LA20249 RS10750
gene id: 1423720:LA20249_RS10750
uniprot id: A0A2K9HRP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1423720:LA20249 RS09455
gene id: 1423720:LA20249_RS09455
uniprot id: A0A2K9HKM0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1423720:LA20249 RS07340
gene id: 1423720:LA20249_RS07340
uniprot id: A0A2K9HHY8
names: Similarity
messages: Belongs to the peptidase C69 family.

1423720:LA20249 RS05285
gene id: 1423720:LA20249_RS05285
uniprot id: A0A2K9HGD7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1423720:LA20249 RS05095
gene id: 1423720:LA20249_RS05095
uniprot id: A0A2K9HQ23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1423720:LA20249 RS04575
gene id: 1423720:LA20249_RS04575
uniprot id: A0A2K9HG40
names: Similarity
messages: Belongs to the glutamine synthetase family.

1423720:LA20249 RS05125
gene id: 1423720:LA20249_RS05125
uniprot id: A0A2K9HIJ2
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1423720:LA20249 RS09290
gene id: 1423720:LA20249_RS09290
uniprot id: A0A2K9HRA3
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS09320
gene id: 1423720:LA20249_RS09320
uniprot id: A0A2K9HJ08
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1423720:LA20249 RS08045
gene id: 1423720:LA20249_RS08045
uniprot id: A0A2K9HHV3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1423720:LA20249 RS10475
gene id: 1423720:LA20249_RS10475
uniprot id: A0A2K9HJ77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1423720:LA20249 RS05545
gene id: 1423720:LA20249_RS05545
uniprot id: A0A2K9HQ73
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1423720:LA20249 RS00215
gene id: 1423720:LA20249_RS00215
uniprot id: A0A2K9HEF8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1423720:LA20249 RS01910
gene id: 1423720:LA20249_RS01910
uniprot id: A0A2K9HF77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1423720:LA20249 RS10420
gene id: 1423720:LA20249_RS10420
uniprot id: A0A2K9HPV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1423720:LA20249 RS05525
gene id: 1423720:LA20249_RS05525
uniprot id: A0A2K9HH04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS01235
gene id: 1423720:LA20249_RS01235
uniprot id: A0A2K9HLW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1423720:LA20249 RS03575
gene id: 1423720:LA20249_RS03575
uniprot id: A0A2K9HFJ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1423720:LA20249 RS09240
gene id: 1423720:LA20249_RS09240
uniprot id: A0A2K9HPH7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1423720:LA20249 RS08075
gene id: 1423720:LA20249_RS08075
uniprot id: A0A2K9HK82
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1423720:LA20249 RS00465
gene id: 1423720:LA20249_RS00465
uniprot id: A0A2K9HEH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1423720:LA20249 RS07985
gene id: 1423720:LA20249_RS07985
uniprot id: A0A2K9HHV9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1423720:LA20249 RS01695
gene id: 1423720:LA20249_RS01695
uniprot id: A0A2K9HH20
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1423720:LA20249 RS09920
gene id: 1423720:LA20249_RS09920
uniprot id: A0A2K9HIV1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1423720:LA20249 RS11575
gene id: 1423720:LA20249_RS11575
uniprot id: A0A2K9HQF3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1423720:LA20249 RS09985
gene id: 1423720:LA20249_RS09985
uniprot id: A0A2K9HKU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1423720:LA20249 RS03780
gene id: 1423720:LA20249_RS03780
uniprot id: A0A2K9HI41
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1423720:LA20249 RS07875
gene id: 1423720:LA20249_RS07875
uniprot id: A0A2K9HI84
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS05880
gene id: 1423720:LA20249_RS05880
uniprot id: A0A2K9HNF5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1423720:LA20249 RS00550
gene id: 1423720:LA20249_RS00550
uniprot id: A0A2K9HE03
names: Function
messages: Required for transformation and DNA binding.

1423720:LA20249 RS04520
gene id: 1423720:LA20249_RS04520
uniprot id: A0A2K9HG24
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS10685
gene id: 1423720:LA20249_RS10685
uniprot id: A0A2K9HJC1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1423720:LA20249 RS06805
gene id: 1423720:LA20249_RS06805
uniprot id: A0A2K9HJL5
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS04070
gene id: 1423720:LA20249_RS04070
uniprot id: A0A2K9HI88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1423720:LA20249 RS01510
gene id: 1423720:LA20249_RS01510
uniprot id: A0A2K9HNZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1423720:LA20249 RS02180
gene id: 1423720:LA20249_RS02180
uniprot id: A0A2K9HHA8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1423720:LA20249 RS04115
gene id: 1423720:LA20249_RS04115
uniprot id: A0A2K9HI18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1423720:LA20249 RS09365
gene id: 1423720:LA20249_RS09365
uniprot id: A0A2K9HKI3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS01690
gene id: 1423720:LA20249_RS01690
uniprot id: A0A2K9HGT3
names: Subcellular Location Annotation
messages: Cytoplasm

1423720:LA20249 RS08790
gene id: 1423720:LA20249_RS08790
uniprot id: A0A2K9HIA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1423720:LA20249 RS06425
gene id: 1423720:LA20249_RS06425
uniprot id: A0A2K9HH34
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1423720:LA20249 RS02570
gene id: 1423720:LA20249_RS02570
uniprot id: A0A2K9HH85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1423720:LA20249 RS04275
gene id: 1423720:LA20249_RS04275
uniprot id: A0A2K9HKM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1423720:LA20249 RS09860
gene id: 1423720:LA20249_RS09860
uniprot id: A0A2K9HRF5
names: Similarity
messages: Belongs to the peptidase M13 family.

1423720:LA20249 RS10495
gene id: 1423720:LA20249_RS10495
uniprot id: A0A2K9HPW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1423720:LA20249 RS04580
gene id: 1423720:LA20249_RS04580
uniprot id: A0A2K9HG35
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1423720:LA20249 RS05470
gene id: 1423720:LA20249_RS05470
uniprot id: A0A2K9HGZ6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1423720:LA20249 RS08245
gene id: 1423720:LA20249_RS08245
uniprot id: A0A2K9HHZ6
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

1423720:LA20249 RS03570
gene id: 1423720:LA20249_RS03570
uniprot id: A0A2K9HG23
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1423720:LA20249 RS09710
gene id: 1423720:LA20249_RS09710
uniprot id: A0A2K9HIQ7
names: Similarity
messages: Belongs to the peptidase C69 family.

1423720:LA20249 RS06330
gene id: 1423720:LA20249_RS06330
uniprot id: A0A2K9HQG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1423720:LA20249 RS06495
gene id: 1423720:LA20249_RS06495
uniprot id: A0A2K9HQI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS05230
gene id: 1423720:LA20249_RS05230
uniprot id: A0A2K9HKZ8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1423720:LA20249 RS04930
gene id: 1423720:LA20249_RS04930
uniprot id: A0A2K9HG91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423720:LA20249 RS08690
gene id: 1423720:LA20249_RS08690
uniprot id: A0A2K9HI81
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS00425
gene id: 1423720:LA20249_RS00425
uniprot id: A0A2K9HDY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1423720:LA20249 RS10870
gene id: 1423720:LA20249_RS10870
uniprot id: A0A2K9HJD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1423720:LA20249 RS04220
gene id: 1423720:LA20249_RS04220
uniprot id: A0A2K9HFV8
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS05175
gene id: 1423720:LA20249_RS05175
uniprot id: A0A2K9HIK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS03720
gene id: 1423720:LA20249_RS03720
uniprot id: A0A2K9HKH0
names: Similarity
messages: Belongs to the RecJ family.

1423720:LA20249 RS01765
gene id: 1423720:LA20249_RS01765
uniprot id: A0A2K9HEL1
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1423720:LA20249 RS00960
gene id: 1423720:LA20249_RS00960
uniprot id: A0A2K9HGG4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1423720:LA20249 RS03715
gene id: 1423720:LA20249_RS03715
uniprot id: A0A2K9HFL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1423720:LA20249 RS08135
gene id: 1423720:LA20249_RS08135
uniprot id: A0A2K9HHY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1423720:LA20249 RS02960
gene id: 1423720:LA20249_RS02960
uniprot id: A0A2K9HHF4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1423720:LA20249 RS10760
gene id: 1423720:LA20249_RS10760
uniprot id: A0A2K9HPY9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1423720:LA20249 RS04465
gene id: 1423720:LA20249_RS04465
uniprot id: A0A2K9HG19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1423720:LA20249 RS02515
gene id: 1423720:LA20249_RS02515
uniprot id: A0A2K9HFI5
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

1423720:LA20249 RS06400
gene id: 1423720:LA20249_RS06400
uniprot id: A0A2K9HH01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1423720:LA20249 RS03035
gene id: 1423720:LA20249_RS03035
uniprot id: A0A2K9HF87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1423720:LA20249 RS06590
gene id: 1423720:LA20249_RS06590
uniprot id: A0A2K9HH63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1423720:LA20249 RS08055
gene id: 1423720:LA20249_RS08055
uniprot id: A0A2K9HP47
names: Similarity
messages: Belongs to the ParB family.

1423720:LA20249 RS05140
gene id: 1423720:LA20249_RS05140
uniprot id: A0A2K9HGD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1423720:LA20249 RS06285
gene id: 1423720:LA20249_RS06285
uniprot id: A0A2K9HGY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS05815
gene id: 1423720:LA20249_RS05815
uniprot id: A0A2K9HQA3
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS08505
gene id: 1423720:LA20249_RS08505
uniprot id: A0A2K9HM75
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1423720:LA20249 RS02535
gene id: 1423720:LA20249_RS02535
uniprot id: A0A2K9HEZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1423720:LA20249 RS08890
gene id: 1423720:LA20249_RS08890
uniprot id: A0A2K9HIS8
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS03925
gene id: 1423720:LA20249_RS03925
uniprot id: A0A2K9HMS5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1423720:LA20249 RS01305
gene id: 1423720:LA20249_RS01305
uniprot id: A0A2K9HJH1
names: Similarity
messages: Belongs to the UPF0145 family.

1423720:LA20249 RS04505
gene id: 1423720:LA20249_RS04505
uniprot id: A0A2K9HGI7
names: Similarity
messages: Belongs to the UPF0342 family.

1423720:LA20249 RS04085
gene id: 1423720:LA20249_RS04085
uniprot id: A0A2K9HFU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1423720:LA20249 RS03910
gene id: 1423720:LA20249_RS03910
uniprot id: A0A2K9HFR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1423720:LA20249 RS06970
gene id: 1423720:LA20249_RS06970
uniprot id: A0A2K9HJN9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423720:LA20249 RS04375
gene id: 1423720:LA20249_RS04375
uniprot id: A0A2K9HMY8
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

1423720:LA20249 RS05945
gene id: 1423720:LA20249_RS05945
uniprot id: A0A2K9HLA6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1423720:LA20249 RS00475
gene id: 1423720:LA20249_RS00475
uniprot id: A0A2K9HDZ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1423720:LA20249 RS11000
gene id: 1423720:LA20249_RS11000
uniprot id: A0A2K9HJI5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1423720:LA20249 RS01265
gene id: 1423720:LA20249_RS01265
uniprot id: A0A2K9HEC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

1423720:LA20249 RS08345
gene id: 1423720:LA20249_RS08345
uniprot id: A0A2K9HKB5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1423720:LA20249 RS10935
gene id: 1423720:LA20249_RS10935
uniprot id: A0A2K9HL79
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS04410
gene id: 1423720:LA20249_RS04410
uniprot id: A0A2K9HG02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1423720:LA20249 RS05870
gene id: 1423720:LA20249_RS05870
uniprot id: A0A2K9HQA9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1423720:LA20249 RS08410
gene id: 1423720:LA20249_RS08410
uniprot id: A0A2K9HI26
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS02865
gene id: 1423720:LA20249_RS02865
uniprot id: A0A2K9HF62
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS06380
gene id: 1423720:LA20249_RS06380
uniprot id: A0A2K9HLI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS00055
gene id: 1423720:LA20249_RS00055
uniprot id: A0A2N9YJP8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1423720:LA20249 RS01080
gene id: 1423720:LA20249_RS01080
uniprot id: A0A2K9HJD6
names: Similarity
messages: Belongs to the UPF0735 family.

1423720:LA20249 RS04980
gene id: 1423720:LA20249_RS04980
uniprot id: A0A2K9HGQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1423720:LA20249 RS01125
gene id: 1423720:LA20249_RS01125
uniprot id: A0A2K9HJN8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS07615
gene id: 1423720:LA20249_RS07615
uniprot id: A0A2K9HK03
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS08335
gene id: 1423720:LA20249_RS08335
uniprot id: A0A2K9HM53
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1423720:LA20249 RS03045
gene id: 1423720:LA20249_RS03045
uniprot id: A0A2K9HF92
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS08500
gene id: 1423720:LA20249_RS08500
uniprot id: A0A2K9HI34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1423720:LA20249 RS00620
gene id: 1423720:LA20249_RS00620
uniprot id: A0A2K9HE14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS09245
gene id: 1423720:LA20249_RS09245
uniprot id: A0A2K9HIH4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1423720:LA20249 RS09425
gene id: 1423720:LA20249_RS09425
uniprot id: A0A2K9HRB2
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS05375
gene id: 1423720:LA20249_RS05375
uniprot id: A0A2K9HGH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1423720:LA20249 RS01535
gene id: 1423720:LA20249_RS01535
uniprot id: A0A2K9HGZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1423720:LA20249 RS05000
gene id: 1423720:LA20249_RS05000
uniprot id: A0A2K9HQ11
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1423720:LA20249 RS04255
gene id: 1423720:LA20249_RS04255
uniprot id: A0A2K9HFX0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1423720:LA20249 RS11085
gene id: 1423720:LA20249_RS11085
uniprot id: A0A2K9HN44
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1423720:LA20249 RS04635
gene id: 1423720:LA20249_RS04635
uniprot id: A0A2K9HGL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1423720:LA20249 RS01780
gene id: 1423720:LA20249_RS01780
uniprot id: A0A2K9HLE9
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1423720:LA20249 RS02150
gene id: 1423720:LA20249_RS02150
uniprot id: A0A2K9HET0
names: Similarity
messages: Belongs to the fructosamine kinase family.

1423720:LA20249 RS04370
gene id: 1423720:LA20249_RS04370
uniprot id: A0A2K9HPV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

1423720:LA20249 RS05630
gene id: 1423720:LA20249_RS05630
uniprot id: A0A2K9HH28
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1423720:LA20249 RS03745
gene id: 1423720:LA20249_RS03745
uniprot id: A0A2K9HFN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1423720:LA20249 RS08770
gene id: 1423720:LA20249_RS08770
uniprot id: A0A2K9HKC5
names: Similarity
messages: Belongs to the asp23 family.

1423720:LA20249 RS08965
gene id: 1423720:LA20249_RS08965
uniprot id: A0A2K9HIC0
names: Similarity
messages: Belongs to the UPF0111 family.

1423720:LA20249 RS09690
gene id: 1423720:LA20249_RS09690
uniprot id: A0A2K9HIR6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1423720:LA20249 RS04360
gene id: 1423720:LA20249_RS04360
uniprot id: A0A2K9HFZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1423720:LA20249 RS03785
gene id: 1423720:LA20249_RS03785
uniprot id: A0A2K9HG65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1423720:LA20249 RS11545
gene id: 1423720:LA20249_RS11545
uniprot id: A0A2K9HLQ7
names: Similarity
messages: Belongs to the zeta toxin family.

1423720:LA20249 RS10530
gene id: 1423720:LA20249_RS10530
uniprot id: A0A2K9HJ88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1423720:LA20249 RS10395
gene id: 1423720:LA20249_RS10395
uniprot id: A0A2K9HJL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1423720:LA20249 RS10835
gene id: 1423720:LA20249_RS10835
uniprot id: A0A2K9HJU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1423720:LA20249 RS01495
gene id: 1423720:LA20249_RS01495
uniprot id: A0A2K9HEG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS07630
gene id: 1423720:LA20249_RS07630
uniprot id: A0A2K9HHM6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423720:LA20249 RS02020
gene id: 1423720:LA20249_RS02020
uniprot id: A0A2K9HER8
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS09490
gene id: 1423720:LA20249_RS09490
uniprot id: A0A2K9HIL5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1423720:LA20249 RS03930
gene id: 1423720:LA20249_RS03930
uniprot id: A0A2K9HFQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

1423720:LA20249 RS01440
gene id: 1423720:LA20249_RS01440
uniprot id: A0A2K9HEF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1423720:LA20249 RS05180
gene id: 1423720:LA20249_RS05180
uniprot id: A0A2K9HIS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1423720:LA20249 RS01565
gene id: 1423720:LA20249_RS01565
uniprot id: A0A2K9HNZ5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1423720:LA20249 RS10895
gene id: 1423720:LA20249_RS10895
uniprot id: A0A2K9HJG6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1423720:LA20249 RS01480
gene id: 1423720:LA20249_RS01480
uniprot id: A0A2K9HGP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1423720:LA20249 RS02315
gene id: 1423720:LA20249_RS02315
uniprot id: A0A2K9HP80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1423720:LA20249 RS07995
gene id: 1423720:LA20249_RS07995
uniprot id: A0A2K9HHU5
names: Similarity
messages: Belongs to the peptidase S11 family.

1423720:LA20249 RS11140
gene id: 1423720:LA20249_RS11140
uniprot id: A0A2K9HLL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1423720:LA20249 RS09100
gene id: 1423720:LA20249_RS09100
uniprot id: A0A2K9HKF8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1423720:LA20249 RS03280
gene id: 1423720:LA20249_RS03280
uniprot id: A0A2K9HHL0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1423720:LA20249 RS01655
gene id: 1423720:LA20249_RS01655
uniprot id: A0A2K9HLB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS10200
gene id: 1423720:LA20249_RS10200
uniprot id: A0A2K9HJ21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS05995
gene id: 1423720:LA20249_RS05995
uniprot id: A0A2K9HNH4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1423720:LA20249 RS01520
gene id: 1423720:LA20249_RS01520
uniprot id: A0A2K9HEG7
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS08215
gene id: 1423720:LA20249_RS08215
uniprot id: A0A2K9HHY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1423720:LA20249 RS08350
gene id: 1423720:LA20249_RS08350
uniprot id: A0A2K9HII1
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1423720:LA20249 RS03920
gene id: 1423720:LA20249_RS03920
uniprot id: A0A2K9HPQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1423720:LA20249 RS07000
gene id: 1423720:LA20249_RS07000
uniprot id: A0A2K9HNS7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS00060
gene id: 1423720:LA20249_RS00060
uniprot id: A0A2N9YJQ4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1423720:LA20249 RS03095
gene id: 1423720:LA20249_RS03095
uniprot id: A0A2K9HFA3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS11530
gene id: 1423720:LA20249_RS11530
uniprot id: A0A2K9HK34
names: Similarity
messages: Belongs to the MobA/MobL family.

1423720:LA20249 RS05645
gene id: 1423720:LA20249_RS05645
uniprot id: A0A2K9HGM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1423720:LA20249 RS00900
gene id: 1423720:LA20249_RS00900
uniprot id: A0A2K9HJL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS01210
gene id: 1423720:LA20249_RS01210
uniprot id: A0A2K9HEU9
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS04660
gene id: 1423720:LA20249_RS04660
uniprot id: A0A2K9HPY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS02855
gene id: 1423720:LA20249_RS02855
uniprot id: A0A2K9HFP4
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1423720:LA20249 RS11020
gene id: 1423720:LA20249_RS11020
uniprot id: A0A2K9HQ22
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1423720:LA20249 RS07350
gene id: 1423720:LA20249_RS07350
uniprot id: A0A2K9HHH8
names: Similarity
messages: Belongs to the EamA transporter family.

1423720:LA20249 RS06250
gene id: 1423720:LA20249_RS06250
uniprot id: A0A2K9HJC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1423720:LA20249 RS09715
gene id: 1423720:LA20249_RS09715
uniprot id: A0A2K9HML9
names: Similarity
messages: Belongs to the peptidase C69 family.

1423720:LA20249 RS03985
gene id: 1423720:LA20249_RS03985
uniprot id: A0A2K9HMT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1423720:LA20249 RS00490
gene id: 1423720:LA20249_RS00490
uniprot id: A0A2K9HNN5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1423720:LA20249 RS01570
gene id: 1423720:LA20249_RS01570
uniprot id: A0A2K9HM07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1423720:LA20249 RS02325
gene id: 1423720:LA20249_RS02325
uniprot id: A0A2K9HEV9
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1423720:LA20249 RS05165
gene id: 1423720:LA20249_RS05165
uniprot id: A0A2K9HGB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1423720:LA20249 RS07930
gene id: 1423720:LA20249_RS07930
uniprot id: A0A2K9HI98
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1423720:LA20249 RS01930
gene id: 1423720:LA20249_RS01930
uniprot id: A0A2K9HP40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1423720:LA20249 RS04270
gene id: 1423720:LA20249_RS04270
uniprot id: A0A2K9HFW7
names: Similarity
messages: Belongs to the acylphosphatase family.

1423720:LA20249 RS02230
gene id: 1423720:LA20249_RS02230
uniprot id: A0A2K9HHB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1423720:LA20249 RS05475
gene id: 1423720:LA20249_RS05475
uniprot id: A0A2K9HGL0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1423720:LA20249 RS04855
gene id: 1423720:LA20249_RS04855
uniprot id: A0A2K9HGN7
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS05550
gene id: 1423720:LA20249_RS05550
uniprot id: A0A2K9HNB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS11165
gene id: 1423720:LA20249_RS11165
uniprot id: A0A2K9HJJ7
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1423720:LA20249 RS01200
gene id: 1423720:LA20249_RS01200
uniprot id: A0A2K9HGK2
names: Similarity
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Homotetramer.

1423720:LA20249 RS07185
gene id: 1423720:LA20249_RS07185
uniprot id: A0A2K9HHG7
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1423720:LA20249 RS08570
gene id: 1423720:LA20249_RS08570
uniprot id: A0A2K9HKD3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1423720:LA20249 RS10675
gene id: 1423720:LA20249_RS10675
uniprot id: A0A2K9HL39
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS06710
gene id: 1423720:LA20249_RS06710
uniprot id: A0A2K9HH83
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1423720:LA20249 RS06025
gene id: 1423720:LA20249_RS06025
uniprot id: A0A2K9HJ85
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS01630
gene id: 1423720:LA20249_RS01630
uniprot id: A0A2K9HJM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1423720:LA20249 RS07705
gene id: 1423720:LA20249_RS07705
uniprot id: A0A2K9HLX9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423720:LA20249 RS08550
gene id: 1423720:LA20249_RS08550
uniprot id: A0A2K9HP98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS04195
gene id: 1423720:LA20249_RS04195
uniprot id: A0A2K9HFW8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1423720:LA20249 RS03955
gene id: 1423720:LA20249_RS03955
uniprot id: A0A2K9HFR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1423720:LA20249 RS03970
gene id: 1423720:LA20249_RS03970
uniprot id: A0A2K9HPQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1423720:LA20249 RS07825
gene id: 1423720:LA20249_RS07825
uniprot id: A0A2K9HI76
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1423720:LA20249 RS10955
gene id: 1423720:LA20249_RS10955
uniprot id: A0A2K9HJE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1423720:LA20249 RS02320
gene id: 1423720:LA20249_RS02320
uniprot id: A0A2K9HM95
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS10230
gene id: 1423720:LA20249_RS10230
uniprot id: A0A2K9HMS8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS10430
gene id: 1423720:LA20249_RS10430
uniprot id: A0A2K9HMV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1423720:LA20249 RS01590
gene id: 1423720:LA20249_RS01590
uniprot id: A0A2K9HH00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1423720:LA20249 RS09530
gene id: 1423720:LA20249_RS09530
uniprot id: A0A2K9HIM0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423720:LA20249 RS11590
gene id: 1423720:LA20249_RS11590
uniprot id: A0A2K9HK05
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1423720:LA20249 RS04355
gene id: 1423720:LA20249_RS04355
uniprot id: A0A2K9HFZ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1423720:LA20249 RS09380
gene id: 1423720:LA20249_RS09380
uniprot id: A0A2K9HIM1
names: Similarity
messages: Belongs to the peptidase C69 family.

1423720:LA20249 RS01860
gene id: 1423720:LA20249_RS01860
uniprot id: A0A2K9HF67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1423720:LA20249 RS00460
gene id: 1423720:LA20249_RS00460
uniprot id: A0A2K9HGH0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1423720:LA20249 RS07715
gene id: 1423720:LA20249_RS07715
uniprot id: A0A2K9HK24
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1423720:LA20249 RS04320
gene id: 1423720:LA20249_RS04320
uniprot id: A0A2K9HMX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1423720:LA20249 RS05445
gene id: 1423720:LA20249_RS05445
uniprot id: A0A2K9HNA5
names: Subcellular Location Annotation
messages: Cytoplasm

1423720:LA20249 RS05405
gene id: 1423720:LA20249_RS05405
uniprot id: A0A2K9HL22
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

1423720:LA20249 RS07430
gene id: 1423720:LA20249_RS07430
uniprot id: A0A2K9HQS0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423720:LA20249 RS03210
gene id: 1423720:LA20249_RS03210
uniprot id: A0A2K9HMJ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1423720:LA20249 RS10290
gene id: 1423720:LA20249_RS10290
uniprot id: A0A2K9HKY7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1423720:LA20249 RS04820
gene id: 1423720:LA20249_RS04820
uniprot id: A0A2K9HJT6
names: Similarity
messages: Belongs to the DCK/DGK family.

1423720:LA20249 RS02885
gene id: 1423720:LA20249_RS02885
uniprot id: A0A2K9HPD6
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1423720:LA20249 RS11445
gene id: 1423720:LA20249_RS11445
uniprot id: A0A2K9HLP2
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1423720:LA20249 RS10940
gene id: 1423720:LA20249_RS10940
uniprot id: A0A2K9HJW7
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS06095
gene id: 1423720:LA20249_RS06095
uniprot id: A0A2K9HHB3
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS06290
gene id: 1423720:LA20249_RS06290
uniprot id: A0A2K9HLF1
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

1423720:LA20249 RS06580
gene id: 1423720:LA20249_RS06580
uniprot id: A0A2K9HJH7
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS01410
gene id: 1423720:LA20249_RS01410
uniprot id: A0A2K9HLY8
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS01470
gene id: 1423720:LA20249_RS01470
uniprot id: A0A2K9HEF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1423720:LA20249 RS09945
gene id: 1423720:LA20249_RS09945
uniprot id: A0A2K9HIX2
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS01600
gene id: 1423720:LA20249_RS01600
uniprot id: A0A2K9HEJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1423720:LA20249 RS01735
gene id: 1423720:LA20249_RS01735
uniprot id: A0A2K9HJP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1423720:LA20249 RS04715
gene id: 1423720:LA20249_RS04715
uniprot id: A0A2K9HG61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1423720:LA20249 RS06630
gene id: 1423720:LA20249_RS06630
uniprot id: A0A2K9HH41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

1423720:LA20249 RS07960
gene id: 1423720:LA20249_RS07960
uniprot id: A0A2K9HHT8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS08885
gene id: 1423720:LA20249_RS08885
uniprot id: A0A2K9HKG7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1423720:LA20249 RS01975
gene id: 1423720:LA20249_RS01975
uniprot id: A0A2K9HEQ1
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1423720:LA20249 RS01425
gene id: 1423720:LA20249_RS01425
uniprot id: A0A2K9HGN3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS02345
gene id: 1423720:LA20249_RS02345
uniprot id: A0A2K9HHD5
names: Similarity
messages: Belongs to the CvfB family.

1423720:LA20249 RS08665
gene id: 1423720:LA20249_RS08665
uniprot id: A0A2K9HM96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS01865
gene id: 1423720:LA20249_RS01865
uniprot id: A0A2K9HEN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS07170
gene id: 1423720:LA20249_RS07170
uniprot id: A0A2K9HJM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1423720:LA20249 RS00545
gene id: 1423720:LA20249_RS00545
uniprot id: A0A2K9HE06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1423720:LA20249 RS08855
gene id: 1423720:LA20249_RS08855
uniprot id: A0A2K9HIA1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1423720:LA20249 RS00800
gene id: 1423720:LA20249_RS00800
uniprot id: A0A2K9HGM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1423720:LA20249 RS04875
gene id: 1423720:LA20249_RS04875
uniprot id: A0A2K9HPZ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1423720:LA20249 RS02450
gene id: 1423720:LA20249_RS02450
uniprot id: A0A2K9HK22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS05195
gene id: 1423720:LA20249_RS05195
uniprot id: A0A2K9HQ88
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1423720:LA20249 RS04700
gene id: 1423720:LA20249_RS04700
uniprot id: A0A2K9HIJ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS09390
gene id: 1423720:LA20249_RS09390
uniprot id: A0A2K9HIL7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1423720:LA20249 RS03515
gene id: 1423720:LA20249_RS03515
uniprot id: A0A2K9HFI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1423720:LA20249 RS03940
gene id: 1423720:LA20249_RS03940
uniprot id: A0A2K9HHY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1423720:LA20249 RS05650
gene id: 1423720:LA20249_RS05650
uniprot id: A0A2K9HQ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

1423720:LA20249 RS11050
gene id: 1423720:LA20249_RS11050
uniprot id: A0A2K9HJJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1423720:LA20249 RS07300
gene id: 1423720:LA20249_RS07300
uniprot id: A0A2K9HHG6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1423720:LA20249 RS09075
gene id: 1423720:LA20249_RS09075
uniprot id: A0A2K9HR82
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1423720:LA20249 RS08040
gene id: 1423720:LA20249_RS08040
uniprot id: A0A2K9HHV6
names: Subcellular Location Annotation
messages: Cell membrane

1423720:LA20249 RS09375
gene id: 1423720:LA20249_RS09375
uniprot id: A0A2K9HJ18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1423720:LA20249 RS02395
gene id: 1423720:LA20249_RS02395
uniprot id: A0A2K9HK11
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1423720:LA20249 RS03145
gene id: 1423720:LA20249_RS03145
uniprot id: A0A2K9HFB7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1423720:LA20249 RS11295
gene id: 1423720:LA20249_RS11295
uniprot id: A0A2K9HJZ0
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1423720:LA20249 RS11465
gene id: 1423720:LA20249_RS11465
uniprot id: A0A2K9HK16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1423720:LA20249 RS03450
gene id: 1423720:LA20249_RS03450
uniprot id: A0A2K9HHX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS04745
gene id: 1423720:LA20249_RS04745
uniprot id: A0A2K9HKU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS11330
gene id: 1423720:LA20249_RS11330
uniprot id: A0A2K9HK05
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1423720:LA20249 RS01595
gene id: 1423720:LA20249_RS01595
uniprot id: A0A2K9HF23
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1423720:LA20249 RS11075
gene id: 1423720:LA20249_RS11075
uniprot id: A0A2K9HQ26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1423720:LA20249 RS03835
gene id: 1423720:LA20249_RS03835
uniprot id: A0A2K9HHW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1423720:LA20249 RS11160
gene id: 1423720:LA20249_RS11160
uniprot id: A0A2K9HJL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1423720:LA20249 RS05120
gene id: 1423720:LA20249_RS05120
uniprot id: A0A2K9HRX9
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS02185
gene id: 1423720:LA20249_RS02185
uniprot id: A0A2K9HFC7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423720:LA20249 RS09875
gene id: 1423720:LA20249_RS09875
uniprot id: A0A2K9HMN4
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS03090
gene id: 1423720:LA20249_RS03090
uniprot id: A0A2K9HFA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS10575
gene id: 1423720:LA20249_RS10575
uniprot id: A0A2K9HJP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1423720:LA20249 RS03660
gene id: 1423720:LA20249_RS03660
uniprot id: A0A2K9HFK5
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1423720:LA20249 RS03765
gene id: 1423720:LA20249_RS03765
uniprot id: A0A2K9HFM6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1423720:LA20249 RS01950
gene id: 1423720:LA20249_RS01950
uniprot id: A0A2K9HGY0
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS03510
gene id: 1423720:LA20249_RS03510
uniprot id: A0A2K9HG14
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1423720:LA20249 RS03195
gene id: 1423720:LA20249_RS03195
uniprot id: A0A2K9HFD1
names: Similarity
messages: Belongs to the CFA/CMAS family.

1423720:LA20249 RS05415
gene id: 1423720:LA20249_RS05415
uniprot id: A0A2K9HIW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423720:LA20249 RS04850
gene id: 1423720:LA20249_RS04850
uniprot id: A0A2K9HIL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1423720:LA20249 RS10620
gene id: 1423720:LA20249_RS10620
uniprot id: A0A2K9HL33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1423720:LA20249 RS00150
gene id: 1423720:LA20249_RS00150
uniprot id: A0A2K9HJ09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1423720:LA20249 RS09265
gene id: 1423720:LA20249_RS09265
uniprot id: A0A2K9HKK1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1423720:LA20249 RS00695
gene id: 1423720:LA20249_RS00695
uniprot id: A0A2K9HEL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS10315
gene id: 1423720:LA20249_RS10315
uniprot id: A0A2K9HRJ7
names: Similarity
messages: Belongs to the universal stress protein A family.

1423720:LA20249 RS11180
gene id: 1423720:LA20249_RS11180
uniprot id: A0A2K9HRT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1423720:LA20249 RS05685
gene id: 1423720:LA20249_RS05685
uniprot id: A0A2K9HGP4
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1423720:LA20249 RS12005
gene id: 1423720:LA20249_RS12005
uniprot id: A0A2K9HG51
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1423720:LA20249 RS08535
gene id: 1423720:LA20249_RS08535
uniprot id: A0A2K9HI37
names: Similarity
messages: Belongs to the peptidase C40 family.

1423720:LA20249 RS01960
gene id: 1423720:LA20249_RS01960
uniprot id: A0A2K9HF88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1423720:LA20249 RS07525
gene id: 1423720:LA20249_RS07525
uniprot id: A0A2K9HHK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS04035
gene id: 1423720:LA20249_RS04035
uniprot id: A0A2K9HFT7
names: Caution
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS06940
gene id: 1423720:LA20249_RS06940
uniprot id: A0A2K9HH99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1423720:LA20249 RS05070
gene id: 1423720:LA20249_RS05070
uniprot id: A0A2K9HIQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1423720:LA20249 RS03060
gene id: 1423720:LA20249_RS03060
uniprot id: A0A2K9HF90
names: Caution
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS02110
gene id: 1423720:LA20249_RS02110
uniprot id: A0A2K9HJW0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1423720:LA20249 RS01450
gene id: 1423720:LA20249_RS01450
uniprot id: A0A2K9HEF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1423720:LA20249 RS07480
gene id: 1423720:LA20249_RS07480
uniprot id: A0A2K9HQS8
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1423720:LA20249 RS06855
gene id: 1423720:LA20249_RS06855
uniprot id: A0A2K9HJG0
names: Similarity
messages: Belongs to the EamA transporter family.

1423720:LA20249 RS08580
gene id: 1423720:LA20249_RS08580
uniprot id: A0A2K9HI64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS10850
gene id: 1423720:LA20249_RS10850
uniprot id: A0A2K9HJD5
names: Similarity
messages: Belongs to the TPP enzyme family.

1423720:LA20249 RS10645
gene id: 1423720:LA20249_RS10645
uniprot id: A0A2K9HRN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1423720:LA20249 RS04725
gene id: 1423720:LA20249_RS04725
uniprot id: A0A2K9HPY7
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1423720:LA20249 RS00075
gene id: 1423720:LA20249_RS00075
uniprot id: A0A2N9YJN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1423720:LA20249 RS02285
gene id: 1423720:LA20249_RS02285
uniprot id: A0A2K9HHC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1423720:LA20249 RS07820
gene id: 1423720:LA20249_RS07820
uniprot id: A0A2K9HK41
names: Similarity
messages: Belongs to the esterase D family.

1423720:LA20249 RS02670
gene id: 1423720:LA20249_RS02670
uniprot id: A0A2K9HK61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS11400
gene id: 1423720:LA20249_RS11400
uniprot id: A0A2K9HK17
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS06335
gene id: 1423720:LA20249_RS06335
uniprot id: A0A2K9HNL2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS07310
gene id: 1423720:LA20249_RS07310
uniprot id: A0A2K9HQR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1423720:LA20249 RS11115
gene id: 1423720:LA20249_RS11115
uniprot id: A0A2K9HJH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1423720:LA20249 RS11555
gene id: 1423720:LA20249_RS11555
uniprot id: A0A2K9HJZ0
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1423720:LA20249 RS00795
gene id: 1423720:LA20249_RS00795
uniprot id: A0A2K9HGD4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS10680
gene id: 1423720:LA20249_RS10680
uniprot id: A0A2K9HJR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1423720:LA20249 RS01880
gene id: 1423720:LA20249_RS01880
uniprot id: A0A2K9HP31
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1423720:LA20249 RS01405
gene id: 1423720:LA20249_RS01405
uniprot id: A0A2K9HNX8
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS02340
gene id: 1423720:LA20249_RS02340
uniprot id: A0A2K9HH51
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1423720:LA20249 RS00180
gene id: 1423720:LA20249_RS00180
uniprot id: A0A2K9HDV7
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1423720:LA20249 RS03005
gene id: 1423720:LA20249_RS03005
uniprot id: A0A2K9HF80
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1423720:LA20249 RS01545
gene id: 1423720:LA20249_RS01545
uniprot id: A0A2K9HF13
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1423720:LA20249 RS07805
gene id: 1423720:LA20249_RS07805
uniprot id: A0A2K9HHR1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1423720:LA20249 RS10580
gene id: 1423720:LA20249_RS10580
uniprot id: A0A2K9HJA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1423720:LA20249 RS03305
gene id: 1423720:LA20249_RS03305
uniprot id: A0A2K9HFE8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1423720:LA20249 RS10665
gene id: 1423720:LA20249_RS10665
uniprot id: A0A2K9HL05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1423720:LA20249 RS10040
gene id: 1423720:LA20249_RS10040
uniprot id: A0A2K9HJE0
names: Similarity
messages: Belongs to the TPP enzyme family.

1423720:LA20249 RS09770
gene id: 1423720:LA20249_RS09770
uniprot id: A0A2K9HMM2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS08250
gene id: 1423720:LA20249_RS08250
uniprot id: A0A2K9HHZ0
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS05090
gene id: 1423720:LA20249_RS05090
uniprot id: A0A2K9HGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1423720:LA20249 RS04595
gene id: 1423720:LA20249_RS04595
uniprot id: A0A2K9HNB3
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS08295
gene id: 1423720:LA20249_RS08295
uniprot id: A0A2K9HIH1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS08825
gene id: 1423720:LA20249_RS08825
uniprot id: A0A2K9HMB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS10325
gene id: 1423720:LA20249_RS10325
uniprot id: A0A2K9HJ32
names: Similarity
messages: Belongs to the polypeptide deformylase family.

1423720:LA20249 RS10440
gene id: 1423720:LA20249_RS10440
uniprot id: A0A2K9HL07
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1423720:LA20249 RS00080
gene id: 1423720:LA20249_RS00080
uniprot id: A0A2K9HLC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1423720:LA20249 RS07520
gene id: 1423720:LA20249_RS07520
uniprot id: A0A2K9HHK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1423720:LA20249 RS08900
gene id: 1423720:LA20249_RS08900
uniprot id: A0A2K9HIC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1423720:LA20249 RS10275
gene id: 1423720:LA20249_RS10275
uniprot id: A0A2K9HJ22
names: Similarity
messages: Belongs to the EamA transporter family.

1423720:LA20249 RS01775
gene id: 1423720:LA20249_RS01775
uniprot id: A0A2K9HM32
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1423720:LA20249 RS04245
gene id: 1423720:LA20249_RS04245
uniprot id: A0A2K9HFX6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1423720:LA20249 RS05500
gene id: 1423720:LA20249_RS05500
uniprot id: A0A2K9HK89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1423720:LA20249 RS10875
gene id: 1423720:LA20249_RS10875
uniprot id: A0A2K9HN17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1423720:LA20249 RS10535
gene id: 1423720:LA20249_RS10535
uniprot id: A0A2K9HJ73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1423720:LA20249 RS07285
gene id: 1423720:LA20249_RS07285
uniprot id: A0A2K9HJU8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1423720:LA20249 RS04615
gene id: 1423720:LA20249_RS04615
uniprot id: A0A2K9HKS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1423720:LA20249 RS05980
gene id: 1423720:LA20249_RS05980
uniprot id: A0A2K9HGT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1423720:LA20249 RS08455
gene id: 1423720:LA20249_RS08455
uniprot id: A0A2K9HM66
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS10990
gene id: 1423720:LA20249_RS10990
uniprot id: A0A2K9HL85
names: Similarity
messages: Belongs to the ycf81 family.

1423720:LA20249 RS03260
gene id: 1423720:LA20249_RS03260
uniprot id: A0A2K9HPH9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS10390
gene id: 1423720:LA20249_RS10390
uniprot id: A0A2K9HL02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1423720:LA20249 RS01610
gene id: 1423720:LA20249_RS01610
uniprot id: A0A2K9HEI4
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1423720:LA20249 RS07405
gene id: 1423720:LA20249_RS07405
uniprot id: A0A2K9HHZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1423720:LA20249 RS05050
gene id: 1423720:LA20249_RS05050
uniprot id: A0A2K9HQ17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1423720:LA20249 RS08590
gene id: 1423720:LA20249_RS08590
uniprot id: A0A2K9HI48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1423720:LA20249 RS06090
gene id: 1423720:LA20249_RS06090
uniprot id: A0A2K9HJ92
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS08210
gene id: 1423720:LA20249_RS08210
uniprot id: A0A2K9HP64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1423720:LA20249 RS10480
gene id: 1423720:LA20249_RS10480
uniprot id: A0A2K9HJ64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1423720:LA20249 RS10610
gene id: 1423720:LA20249_RS10610
uniprot id: A0A2K9HMX5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1423720:LA20249 RS02815
gene id: 1423720:LA20249_RS02815
uniprot id: A0A2K9HF50
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1423720:LA20249 RS03815
gene id: 1423720:LA20249_RS03815
uniprot id: A0A2K9HPP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1423720:LA20249 RS06620
gene id: 1423720:LA20249_RS06620
uniprot id: A0A2K9HNP2
names: Similarity
messages: Belongs to the DltD family.

1423720:LA20249 RS01750
gene id: 1423720:LA20249_RS01750
uniprot id: A0A2K9HF52
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1423720:LA20249 RS03180
gene id: 1423720:LA20249_RS03180
uniprot id: A0A2K9HHT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1423720:LA20249 RS04940
gene id: 1423720:LA20249_RS04940
uniprot id: A0A2K9HQ06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1423720:LA20249 RS01310
gene id: 1423720:LA20249_RS01310
uniprot id: A0A2K9HGL5
names: Similarity
messages: Belongs to the peptidase C69 family.

1423720:LA20249 RS00050
gene id: 1423720:LA20249_RS00050
uniprot id: A0A2N9YJP0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1423720:LA20249 RS08240
gene id: 1423720:LA20249_RS08240
uniprot id: A0A2K9HI06
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1423720:LA20249 RS00520
gene id: 1423720:LA20249_RS00520
uniprot id: A0A2K9HG86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1423720:LA20249 RS10165
gene id: 1423720:LA20249_RS10165
uniprot id: A0A2K9HRI1
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1423720:LA20249 RS04300
gene id: 1423720:LA20249_RS04300
uniprot id: A0A2K9HFY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1423720:LA20249 RS03905
gene id: 1423720:LA20249_RS03905
uniprot id: A0A2K9HFR0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1423720:LA20249 RS08845
gene id: 1423720:LA20249_RS08845
uniprot id: A0A2K9HIB6
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS06340
gene id: 1423720:LA20249_RS06340
uniprot id: A0A2K9HGZ2
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1423720:LA20249 RS10900
gene id: 1423720:LA20249_RS10900
uniprot id: A0A2K9HJE6
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS10920
gene id: 1423720:LA20249_RS10920
uniprot id: A0A2K9HJE8
names: Similarity
messages: Belongs to the UPF0177 family.

1423720:LA20249 RS03130
gene id: 1423720:LA20249_RS03130
uniprot id: A0A2K9HHS1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1423720:LA20249 RS08260
gene id: 1423720:LA20249_RS08260
uniprot id: A0A2K9HR02
names: Similarity
messages: Belongs to the peptidase S66 family.

1423720:LA20249 RS10590
gene id: 1423720:LA20249_RS10590
uniprot id: A0A2K9HJ79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1423720:LA20249 RS02205
gene id: 1423720:LA20249_RS02205
uniprot id: A0A2K9HP68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1423720:LA20249 RS10635
gene id: 1423720:LA20249_RS10635
uniprot id: A0A2K9HJ95
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1423720:LA20249 RS02375
gene id: 1423720:LA20249_RS02375
uniprot id: A0A2K9HEX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1423720:LA20249 RS05290
gene id: 1423720:LA20249_RS05290
uniprot id: A0A2K9HL06
names: Similarity
names: Subunit
messages: Belongs to the class II ribonucleoside-triphosphate reductase family.
messages: Monomer.

1423720:LA20249 RS00715
gene id: 1423720:LA20249_RS00715
uniprot id: A0A2K9HE28
names: Subcellular Location Annotation
messages: Membrane

1423720:LA20249 RS02435
gene id: 1423720:LA20249_RS02435
uniprot id: A0A2K9HP91
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

1423720:LA20249 RS02660
gene id: 1423720:LA20249_RS02660
uniprot id: A0A2K9HF20
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1423720:LA20249 RS09970
gene id: 1423720:LA20249_RS09970
uniprot id: A0A2K9HIW1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1423720:LA20249 RS00115
gene id: 1423720:LA20249_RS00115
uniprot id: A0A2N9YJQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1423720:LA20249 RS01770
gene id: 1423720:LA20249_RS01770
uniprot id: A0A2K9HP19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1423720:LA20249 RS04135
gene id: 1423720:LA20249_RS04135
uniprot id: A0A2K9HFV7
names: Similarity
messages: Belongs to the asp23 family.

1423720:LA20249 RS05900
gene id: 1423720:LA20249_RS05900
uniprot id: A0A2K9HIZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1423720:LA20249 RS01625
gene id: 1423720:LA20249_RS01625
uniprot id: A0A2K9HEI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1423720:LA20249 RS03225
gene id: 1423720:LA20249_RS03225
uniprot id: A0A2K9HHK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1423720:LA20249 RS04015
gene id: 1423720:LA20249_RS04015
uniprot id: A0A2K9HHZ8
names: Similarity
messages: Belongs to the asp23 family.

1423720:LA20249 RS04350
gene id: 1423720:LA20249_RS04350
uniprot id: A0A2K9HFZ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1423720:LA20249 RS05850
gene id: 1423720:LA20249_RS05850
uniprot id: A0A2K9HH65
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1423720:LA20249 RS03110
gene id: 1423720:LA20249_RS03110
uniprot id: A0A2K9HMI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1423720:LA20249 RS10540
gene id: 1423720:LA20249_RS10540
uniprot id: A0A2K9HJ69
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1423720:LA20249 RS09310
gene id: 1423720:LA20249_RS09310
uniprot id: A0A2K9HKH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm