1420916:AU14 RS08290
gene id: 1420916:AU14_RS08290
uniprot id: W5YHT3
names: Similarity
messages: Belongs to the CFA/CMAS family.

1420916:AU14 RS03780
gene id: 1420916:AU14_RS03780
uniprot id: W5YGR5
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1420916:AU14 RS11035
gene id: 1420916:AU14_RS11035
uniprot id: W5YR96
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1420916:AU14 RS00580
gene id: 1420916:AU14_RS00580
uniprot id: W5YF50
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1420916:AU14 RS16480
gene id: 1420916:AU14_RS16480
uniprot id: W5YKA1
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1420916:AU14 RS08105
gene id: 1420916:AU14_RS08105
uniprot id: W5YQ67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS09665
gene id: 1420916:AU14_RS09665
uniprot id: W5YQS5
names: Similarity
messages: Belongs to the peptidase C40 family.

1420916:AU14 RS12440
gene id: 1420916:AU14_RS12440
uniprot id: W5YRP0
names: Similarity
messages: Belongs to the UPF0234 family.

1420916:AU14 RS15330
gene id: 1420916:AU14_RS15330
uniprot id: W5YKB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1420916:AU14 RS15150
gene id: 1420916:AU14_RS15150
uniprot id: W5YK81
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1420916:AU14 RS09265
gene id: 1420916:AU14_RS09265
uniprot id: W5YIV2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1420916:AU14 RS02975
gene id: 1420916:AU14_RS02975
uniprot id: W5YNF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1420916:AU14 RS00215
gene id: 1420916:AU14_RS00215
uniprot id: W5YME8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1420916:AU14 RS00740
gene id: 1420916:AU14_RS00740
uniprot id: W5YEW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1420916:AU14 RS12695
gene id: 1420916:AU14_RS12695
uniprot id: W5YIY5
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.

1420916:AU14 RS07105
gene id: 1420916:AU14_RS07105
uniprot id: W5YHD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1420916:AU14 RS04090
gene id: 1420916:AU14_RS04090
uniprot id: W5YFX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S16 family.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1420916:AU14 RS18090
gene id: 1420916:AU14_RS18090
uniprot id: W5YKT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1420916:AU14 RS16245
gene id: 1420916:AU14_RS16245
uniprot id: W5YK73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1420916:AU14 RS12635
gene id: 1420916:AU14_RS12635
uniprot id: W5YJB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1420916:AU14 RS13080
gene id: 1420916:AU14_RS13080
uniprot id: W5YJI8
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1420916:AU14 RS07930
gene id: 1420916:AU14_RS07930
uniprot id: W5YHN4
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1420916:AU14 RS08870
gene id: 1420916:AU14_RS08870
uniprot id: W5YQH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1420916:AU14 RS07115
gene id: 1420916:AU14_RS07115
uniprot id: W5YPV3
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1420916:AU14 RS11605
gene id: 1420916:AU14_RS11605
uniprot id: W5YJM9
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1420916:AU14 RS04685
gene id: 1420916:AU14_RS04685
uniprot id: W5YNY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1420916:AU14 RS18580
gene id: 1420916:AU14_RS18580
uniprot id: W5YGU7
names: Similarity
messages: Belongs to the peptidase M17 family.

1420916:AU14 RS15305
gene id: 1420916:AU14_RS15305
uniprot id: W5YJX3
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS16185
gene id: 1420916:AU14_RS16185
uniprot id: W5YK60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1420916:AU14 RS08250
gene id: 1420916:AU14_RS08250
uniprot id: W5YQ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS14835
gene id: 1420916:AU14_RS14835
uniprot id: W5YSN0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1420916:AU14 RS02745
gene id: 1420916:AU14_RS02745
uniprot id: W5YNC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1420916:AU14 RS12940
gene id: 1420916:AU14_RS12940
uniprot id: W5YJG4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1420916:AU14 RS07770
gene id: 1420916:AU14_RS07770
uniprot id: W5YIA7
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1420916:AU14 RS01725
gene id: 1420916:AU14_RS01725
uniprot id: W5YFT1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1420916:AU14 RS05200
gene id: 1420916:AU14_RS05200
uniprot id: W5YGW0
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

1420916:AU14 RS02610
gene id: 1420916:AU14_RS02610
uniprot id: W5YG42
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1420916:AU14 RS03580
gene id: 1420916:AU14_RS03580
uniprot id: W5YGP5
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS07215
gene id: 1420916:AU14_RS07215
uniprot id: W5YI42
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1420916:AU14 RS17225
gene id: 1420916:AU14_RS17225
uniprot id: W5YTD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1420916:AU14 RS09920
gene id: 1420916:AU14_RS09920
uniprot id: W5YI50
names: Similarity
messages: Belongs to the proline racemase family.

1420916:AU14 RS04985
gene id: 1420916:AU14_RS04985
uniprot id: W5YH62
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1420916:AU14 RS06440
gene id: 1420916:AU14_RS06440
uniprot id: W5YGW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1420916:AU14 RS10095
gene id: 1420916:AU14_RS10095
uniprot id: W5YIK8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1420916:AU14 RS01000
gene id: 1420916:AU14_RS01000
uniprot id: W5YL38
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS16555
gene id: 1420916:AU14_RS16555
uniprot id: W5YLA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1420916:AU14 RS01085
gene id: 1420916:AU14_RS01085
uniprot id: W5YEZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1420916:AU14 RS17950
gene id: 1420916:AU14_RS17950
uniprot id: W5YLQ7
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1420916:AU14 RS03785
gene id: 1420916:AU14_RS03785
uniprot id: W5YGF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

1420916:AU14 RS00025
gene id: 1420916:AU14_RS00025
uniprot id: W5YEX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1420916:AU14 RS15270
gene id: 1420916:AU14_RS15270
uniprot id: W5YKA3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1420916:AU14 RS04520
gene id: 1420916:AU14_RS04520
uniprot id: W5YH11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS07865
gene id: 1420916:AU14_RS07865
uniprot id: W5YQ41
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1420916:AU14 RS07280
gene id: 1420916:AU14_RS07280
uniprot id: W5YHF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1420916:AU14 RS13695
gene id: 1420916:AU14_RS13695
uniprot id: W5YUK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS08745
gene id: 1420916:AU14_RS08745
uniprot id: W5YQF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1420916:AU14 RS16530
gene id: 1420916:AU14_RS16530
uniprot id: W5YLA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1420916:AU14 RS12505
gene id: 1420916:AU14_RS12505
uniprot id: W5YIW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1420916:AU14 RS14755
gene id: 1420916:AU14_RS14755
uniprot id: W5YK63
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1420916:AU14 RS17370
gene id: 1420916:AU14_RS17370
uniprot id: W5YLH1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1420916:AU14 RS15285
gene id: 1420916:AU14_RS15285
uniprot id: W5YSS9
names: Similarity
messages: Belongs to the HSP15 family.

1420916:AU14 RS10035
gene id: 1420916:AU14_RS10035
uniprot id: W5YIJ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1420916:AU14 RS13210
gene id: 1420916:AU14_RS13210
uniprot id: W5YJK5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1420916:AU14 RS14430
gene id: 1420916:AU14_RS14430
uniprot id: W5YSJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1420916:AU14 RS14395
gene id: 1420916:AU14_RS14395
uniprot id: W5YJN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

1420916:AU14 RS12810
gene id: 1420916:AU14_RS12810
uniprot id: W5YJE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1420916:AU14 RS03950
gene id: 1420916:AU14_RS03950
uniprot id: W5YG99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1420916:AU14 RS17385
gene id: 1420916:AU14_RS17385
uniprot id: W5YL34
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1420916:AU14 RS07150
gene id: 1420916:AU14_RS07150
uniprot id: W5YI33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1420916:AU14 RS04980
gene id: 1420916:AU14_RS04980
uniprot id: W5YP26
names: Subcellular Location Annotation
messages: Cytoplasm

1420916:AU14 RS17595
gene id: 1420916:AU14_RS17595
uniprot id: W5YL63
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1420916:AU14 RS13580
gene id: 1420916:AU14_RS13580
uniprot id: W5YJR1
names: Similarity
messages: Belongs to the UPF0319 family.

1420916:AU14 RS04635
gene id: 1420916:AU14_RS04635
uniprot id: W5YGP6
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS05865
gene id: 1420916:AU14_RS05865
uniprot id: W5YHI7
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

1420916:AU14 RS01825
gene id: 1420916:AU14_RS01825
uniprot id: W5YG67
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1420916:AU14 RS13430
gene id: 1420916:AU14_RS13430
uniprot id: W5YKA4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1420916:AU14 RS06605
gene id: 1420916:AU14_RS06605
uniprot id: W5YPP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1420916:AU14 RS09275
gene id: 1420916:AU14_RS09275
uniprot id: W5YI74
names: Subcellular Location Annotation
messages: Cell inner membrane

1420916:AU14 RS08545
gene id: 1420916:AU14_RS08545
uniprot id: W5YI11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS16215
gene id: 1420916:AU14_RS16215
uniprot id: W5YT30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1420916:AU14 RS08120
gene id: 1420916:AU14_RS08120
uniprot id: W5YHW0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1420916:AU14 RS00080
gene id: 1420916:AU14_RS00080
uniprot id: W5YLZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1420916:AU14 RS04625
gene id: 1420916:AU14_RS04625
uniprot id: W5YNY2
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1420916:AU14 RS07385
gene id: 1420916:AU14_RS07385
uniprot id: W5YHG8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1420916:AU14 RS17885
gene id: 1420916:AU14_RS17885
uniprot id: W5YLA1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1420916:AU14 RS01600
gene id: 1420916:AU14_RS01600
uniprot id: W5YF62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1420916:AU14 RS00210
gene id: 1420916:AU14_RS00210
uniprot id: W5YEN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1420916:AU14 RS16640
gene id: 1420916:AU14_RS16640
uniprot id: W5YKT2
names: Similarity
messages: Belongs to the WrbA family.

1420916:AU14 RS06315
gene id: 1420916:AU14_RS06315
uniprot id: W5YLF4
names: Similarity
messages: Belongs to the peptidase S8 family.

1420916:AU14 RS03290
gene id: 1420916:AU14_RS03290
uniprot id: W5YNI3
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS09725
gene id: 1420916:AU14_RS09725
uniprot id: W5YQT5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1420916:AU14 RS04965
gene id: 1420916:AU14_RS04965
uniprot id: W5YGM6
names: Similarity
messages: Belongs to the thioredoxin family.

1420916:AU14 RS15650
gene id: 1420916:AU14_RS15650
uniprot id: W5YL14
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1420916:AU14 RS12980
gene id: 1420916:AU14_RS12980
uniprot id: W5YJ24
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1420916:AU14 RS13585
gene id: 1420916:AU14_RS13585
uniprot id: W5YJQ4
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1420916:AU14 RS07990
gene id: 1420916:AU14_RS07990
uniprot id: W5YID3
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1420916:AU14 RS05635
gene id: 1420916:AU14_RS05635
uniprot id: W5YH09
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS02110
gene id: 1420916:AU14_RS02110
uniprot id: W5YN63
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS04725
gene id: 1420916:AU14_RS04725
uniprot id: W5YGQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1420916:AU14 RS13650
gene id: 1420916:AU14_RS13650
uniprot id: W5YJS0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1420916:AU14 RS04425
gene id: 1420916:AU14_RS04425
uniprot id: W5YNV7
names: Similarity
messages: Belongs to the HesB/IscA family.

1420916:AU14 RS13840
gene id: 1420916:AU14_RS13840
uniprot id: W5YJE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1420916:AU14 RS04575
gene id: 1420916:AU14_RS04575
uniprot id: W5YGH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1420916:AU14 RS13030
gene id: 1420916:AU14_RS13030
uniprot id: W5YJ35
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1420916:AU14 RS02705
gene id: 1420916:AU14_RS02705
uniprot id: W5YNB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1420916:AU14 RS10430
gene id: 1420916:AU14_RS10430
uniprot id: W5YR41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1420916:AU14 RS10775
gene id: 1420916:AU14_RS10775
uniprot id: W5YIR8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1420916:AU14 RS03515
gene id: 1420916:AU14_RS03515
uniprot id: W5YGN8
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

1420916:AU14 RS16155
gene id: 1420916:AU14_RS16155
uniprot id: W5YK56
names: Similarity
messages: Belongs to the SlyX family.

1420916:AU14 RS01340
gene id: 1420916:AU14_RS01340
uniprot id: W5YFC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1420916:AU14 RS02085
gene id: 1420916:AU14_RS02085
uniprot id: W5YFZ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS02900
gene id: 1420916:AU14_RS02900
uniprot id: W5YG64
names: Similarity
messages: Belongs to the YfgM family.

1420916:AU14 RS09055
gene id: 1420916:AU14_RS09055
uniprot id: W5YHQ8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1420916:AU14 RS09025
gene id: 1420916:AU14_RS09025
uniprot id: W5YI58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1420916:AU14 RS00480
gene id: 1420916:AU14_RS00480
uniprot id: W5YFE0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1420916:AU14 RS16390
gene id: 1420916:AU14_RS16390
uniprot id: W5YKR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1420916:AU14 RS16920
gene id: 1420916:AU14_RS16920
uniprot id: W5YMK4
names: Subcellular Location Annotation
messages: Virion

1420916:AU14 RS05130
gene id: 1420916:AU14_RS05130
uniprot id: W5YH78
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1420916:AU14 RS07945
gene id: 1420916:AU14_RS07945
uniprot id: W5YIC8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1420916:AU14 RS16635
gene id: 1420916:AU14_RS16635
uniprot id: W5YKV5
names: Similarity
messages: Belongs to the ArsC family.

1420916:AU14 RS04550
gene id: 1420916:AU14_RS04550
uniprot id: W5YG36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1420916:AU14 RS02375
gene id: 1420916:AU14_RS02375
uniprot id: W5YN87
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1420916:AU14 RS16540
gene id: 1420916:AU14_RS16540
uniprot id: W5YKR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1420916:AU14 RS13005
gene id: 1420916:AU14_RS13005
uniprot id: W5YJ29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1420916:AU14 RS07035
gene id: 1420916:AU14_RS07035
uniprot id: W5YHJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS08190
gene id: 1420916:AU14_RS08190
uniprot id: W5YHR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1420916:AU14 RS12945
gene id: 1420916:AU14_RS12945
uniprot id: W5YJG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1420916:AU14 RS13590
gene id: 1420916:AU14_RS13590
uniprot id: W5YJB2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS08015
gene id: 1420916:AU14_RS08015
uniprot id: W5YHP1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1420916:AU14 RS12480
gene id: 1420916:AU14_RS12480
uniprot id: W5YJW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

1420916:AU14 RS13035
gene id: 1420916:AU14_RS13035
uniprot id: W5YRX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1420916:AU14 RS14065
gene id: 1420916:AU14_RS14065
uniprot id: W5YKM5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS03200
gene id: 1420916:AU14_RS03200
uniprot id: W5YNH4
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS14410
gene id: 1420916:AU14_RS14410
uniprot id: W5YKQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1420916:AU14 RS13760
gene id: 1420916:AU14_RS13760
uniprot id: W5YJT2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1420916:AU14 RS03375
gene id: 1420916:AU14_RS03375
uniprot id: W5YFP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1420916:AU14 RS08590
gene id: 1420916:AU14_RS08590
uniprot id: W5YHX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1420916:AU14 RS07210
gene id: 1420916:AU14_RS07210
uniprot id: W5YPW8
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS16500
gene id: 1420916:AU14_RS16500
uniprot id: W5YKR0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS03315
gene id: 1420916:AU14_RS03315
uniprot id: W5YGM0
names: Similarity
messages: Belongs to the peptidase M18 family.

1420916:AU14 RS11640
gene id: 1420916:AU14_RS11640
uniprot id: W5YRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1420916:AU14 RS01235
gene id: 1420916:AU14_RS01235
uniprot id: W5YFB0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS16425
gene id: 1420916:AU14_RS16425
uniprot id: W5YT51
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1420916:AU14 RS11815
gene id: 1420916:AU14_RS11815
uniprot id: W5YRI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1420916:AU14 RS12355
gene id: 1420916:AU14_RS12355
uniprot id: W5YJ86
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1420916:AU14 RS10515
gene id: 1420916:AU14_RS10515
uniprot id: W5YR48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1420916:AU14 RS15900
gene id: 1420916:AU14_RS15900
uniprot id: W5YKK2
names: Similarity
messages: Belongs to the peptidase M1 family.

1420916:AU14 RS03900
gene id: 1420916:AU14_RS03900
uniprot id: W5YGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1420916:AU14 RS12900
gene id: 1420916:AU14_RS12900
uniprot id: W5YJ15
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1420916:AU14 RS03855
gene id: 1420916:AU14_RS03855
uniprot id: W5YFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1420916:AU14 RS12830
gene id: 1420916:AU14_RS12830
uniprot id: W5YJ04
names: Similarity
messages: Belongs to the MotB family.

1420916:AU14 RS18085
gene id: 1420916:AU14_RS18085
uniprot id: W5YLB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1420916:AU14 RS08670
gene id: 1420916:AU14_RS08670
uniprot id: W5YQE1
names: Similarity
messages: Belongs to the UPF0250 family.

1420916:AU14 RS10385
gene id: 1420916:AU14_RS10385
uniprot id: W5YIM5
names: Similarity
messages: Belongs to the MotB family.

1420916:AU14 RS15960
gene id: 1420916:AU14_RS15960
uniprot id: W5YT07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1420916:AU14 RS06060
gene id: 1420916:AU14_RS06060
uniprot id: W5YPJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS05395
gene id: 1420916:AU14_RS05395
uniprot id: W5YU79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1420916:AU14 RS13570
gene id: 1420916:AU14_RS13570
uniprot id: W5YS53
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1420916:AU14 RS14435
gene id: 1420916:AU14_RS14435
uniprot id: W5YKQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1420916:AU14 RS13900
gene id: 1420916:AU14_RS13900
uniprot id: W5YJV5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1420916:AU14 RS00360
gene id: 1420916:AU14_RS00360
uniprot id: W5YF18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

1420916:AU14 RS09320
gene id: 1420916:AU14_RS09320
uniprot id: W5YI79
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1420916:AU14 RS14815
gene id: 1420916:AU14_RS14815
uniprot id: W5YK72
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1420916:AU14 RS15340
gene id: 1420916:AU14_RS15340
uniprot id: W5YST9
names: Similarity
messages: Belongs to the hyi family.

1420916:AU14 RS07540
gene id: 1420916:AU14_RS07540
uniprot id: W5YHI1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1420916:AU14 RS05270
gene id: 1420916:AU14_RS05270
uniprot id: W5YGE1
names: Similarity
messages: Belongs to the universal stress protein A family.

1420916:AU14 RS12675
gene id: 1420916:AU14_RS12675
uniprot id: W5YRR4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1420916:AU14 RS07695
gene id: 1420916:AU14_RS07695
uniprot id: W5YQ20
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1420916:AU14 RS02335
gene id: 1420916:AU14_RS02335
uniprot id: W5YN83
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1420916:AU14 RS12190
gene id: 1420916:AU14_RS12190
uniprot id: W5YIS4
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1420916:AU14 RS07680
gene id: 1420916:AU14_RS07680
uniprot id: W5YHK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

1420916:AU14 RS04375
gene id: 1420916:AU14_RS04375
uniprot id: W5YG16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1420916:AU14 RS18355
gene id: 1420916:AU14_RS18355
uniprot id: W5YTW4
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

1420916:AU14 RS04430
gene id: 1420916:AU14_RS04430
uniprot id: W5YH01
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1420916:AU14 RS18215
gene id: 1420916:AU14_RS18215
uniprot id: W5YKZ4
names: Similarity
messages: Belongs to the YoeB family.

1420916:AU14 RS04690
gene id: 1420916:AU14_RS04690
uniprot id: W5YH28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1420916:AU14 RS15945
gene id: 1420916:AU14_RS15945
uniprot id: W5YK36
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1420916:AU14 RS06570
gene id: 1420916:AU14_RS06570
uniprot id: W5YHE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1420916:AU14 RS12995
gene id: 1420916:AU14_RS12995
uniprot id: W5YJH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1420916:AU14 RS08355
gene id: 1420916:AU14_RS08355
uniprot id: W5YHY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1420916:AU14 RS13535
gene id: 1420916:AU14_RS13535
uniprot id: W5YJP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS03925
gene id: 1420916:AU14_RS03925
uniprot id: W5YGT6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1420916:AU14 RS08865
gene id: 1420916:AU14_RS08865
uniprot id: W5YHN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1420916:AU14 RS01485
gene id: 1420916:AU14_RS01485
uniprot id: W5YFE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1420916:AU14 RS13225
gene id: 1420916:AU14_RS13225
uniprot id: W5YS05
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1420916:AU14 RS16865
gene id: 1420916:AU14_RS16865
uniprot id: W5YTA3
names: Similarity
messages: Belongs to the class II ribonucleoside-triphosphate reductase family.

1420916:AU14 RS11365
gene id: 1420916:AU14_RS11365
uniprot id: W5YRD1
names: Similarity
messages: Belongs to the YicC/YloC family.

1420916:AU14 RS15000
gene id: 1420916:AU14_RS15000
uniprot id: W5YM82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS13075
gene id: 1420916:AU14_RS13075
uniprot id: W5YJI9
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS05530
gene id: 1420916:AU14_RS05530
uniprot id: W5YGV3
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1420916:AU14 RS00800
gene id: 1420916:AU14_RS00800
uniprot id: W5YFI4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1420916:AU14 RS17800
gene id: 1420916:AU14_RS17800
uniprot id: W5YLN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS00585
gene id: 1420916:AU14_RS00585
uniprot id: W5YET8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1420916:AU14 RS02140
gene id: 1420916:AU14_RS02140
uniprot id: W5YLK7
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS06660
gene id: 1420916:AU14_RS06660
uniprot id: W5YGY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1420916:AU14 RS17835
gene id: 1420916:AU14_RS17835
uniprot id: W5YL72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1420916:AU14 RS12320
gene id: 1420916:AU14_RS12320
uniprot id: W5YMJ7
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS13015
gene id: 1420916:AU14_RS13015
uniprot id: W5YK34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1420916:AU14 RS13520
gene id: 1420916:AU14_RS13520
uniprot id: W5YKB6
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

1420916:AU14 RS03035
gene id: 1420916:AU14_RS03035
uniprot id: W5YG81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1420916:AU14 RS02130
gene id: 1420916:AU14_RS02130
uniprot id: W5YFZ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1420916:AU14 RS14635
gene id: 1420916:AU14_RS14635
uniprot id: W5YSL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1420916:AU14 RS14155
gene id: 1420916:AU14_RS14155
uniprot id: W5YKN6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1420916:AU14 RS18145
gene id: 1420916:AU14_RS18145
uniprot id: W5YLD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1420916:AU14 RS17830
gene id: 1420916:AU14_RS17830
uniprot id: W5YM76
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1420916:AU14 RS08480
gene id: 1420916:AU14_RS08480
uniprot id: W5YII4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1420916:AU14 RS16205
gene id: 1420916:AU14_RS16205
uniprot id: W5YKL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1420916:AU14 RS18190
gene id: 1420916:AU14_RS18190
uniprot id: W5YKZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1420916:AU14 RS12340
gene id: 1420916:AU14_RS12340
uniprot id: W5YJV2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1420916:AU14 RS04345
gene id: 1420916:AU14_RS04345
uniprot id: W5YGZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1420916:AU14 RS18200
gene id: 1420916:AU14_RS18200
uniprot id: W5YLY6
names: Similarity
messages: Belongs to the CcdB toxin family.

1420916:AU14 RS09150
gene id: 1420916:AU14_RS09150
uniprot id: W5YQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1420916:AU14 RS12685
gene id: 1420916:AU14_RS12685
uniprot id: W5YJC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1420916:AU14 RS09140
gene id: 1420916:AU14_RS09140
uniprot id: W5YHS0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1420916:AU14 RS07840
gene id: 1420916:AU14_RS07840
uniprot id: W5YIB6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1420916:AU14 RS04175
gene id: 1420916:AU14_RS04175
uniprot id: W5YGJ0
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1420916:AU14 RS15280
gene id: 1420916:AU14_RS15280
uniprot id: W5YJW9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1420916:AU14 RS11040
gene id: 1420916:AU14_RS11040
uniprot id: W5YJI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1420916:AU14 RS11515
gene id: 1420916:AU14_RS11515
uniprot id: W5YJM0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS00690
gene id: 1420916:AU14_RS00690
uniprot id: W5YF66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1420916:AU14 RS04630
gene id: 1420916:AU14_RS04630
uniprot id: W5YH20
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS07285
gene id: 1420916:AU14_RS07285
uniprot id: W5YH38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1420916:AU14 RS14615
gene id: 1420916:AU14_RS14615
uniprot id: W5YK21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1420916:AU14 RS10765
gene id: 1420916:AU14_RS10765
uniprot id: W5YJG1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1420916:AU14 RS02315
gene id: 1420916:AU14_RS02315
uniprot id: W5YFR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1420916:AU14 RS07065
gene id: 1420916:AU14_RS07065
uniprot id: W5YHJ3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1420916:AU14 RS11820
gene id: 1420916:AU14_RS11820
uniprot id: W5YJQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1420916:AU14 RS09705
gene id: 1420916:AU14_RS09705
uniprot id: W5YIF4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1420916:AU14 RS15235
gene id: 1420916:AU14_RS15235
uniprot id: W5YKB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1420916:AU14 RS14860
gene id: 1420916:AU14_RS14860
uniprot id: W5YK51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1420916:AU14 RS09505
gene id: 1420916:AU14_RS09505
uniprot id: W5YIA3
names: Similarity
messages: Belongs to the Gfa family.

1420916:AU14 RS07705
gene id: 1420916:AU14_RS07705
uniprot id: W5YHQ4
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1420916:AU14 RS10685
gene id: 1420916:AU14_RS10685
uniprot id: W5YR64
names: Similarity
messages: Belongs to the FPG family.

1420916:AU14 RS02950
gene id: 1420916:AU14_RS02950
uniprot id: W5YNF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1420916:AU14 RS02405
gene id: 1420916:AU14_RS02405
uniprot id: W5YFH1
names: Similarity
messages: Belongs to the CIA30 family.

1420916:AU14 RS18025
gene id: 1420916:AU14_RS18025
uniprot id: W5YKS5
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1420916:AU14 RS12880
gene id: 1420916:AU14_RS12880
uniprot id: W5YJG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1420916:AU14 RS11950
gene id: 1420916:AU14_RS11950
uniprot id: W5YRJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1420916:AU14 RS10050
gene id: 1420916:AU14_RS10050
uniprot id: W5YR06
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1420916:AU14 RS01670
gene id: 1420916:AU14_RS01670
uniprot id: W5YFH0
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS07890
gene id: 1420916:AU14_RS07890
uniprot id: W5YHN0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1420916:AU14 RS07185
gene id: 1420916:AU14_RS07185
uniprot id: W5YPW3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1420916:AU14 RS02925
gene id: 1420916:AU14_RS02925
uniprot id: W5YNE4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1420916:AU14 RS17670
gene id: 1420916:AU14_RS17670
uniprot id: W5YLL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1420916:AU14 RS11975
gene id: 1420916:AU14_RS11975
uniprot id: W5YRJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1420916:AU14 RS17960
gene id: 1420916:AU14_RS17960
uniprot id: W5YL92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1420916:AU14 RS07460
gene id: 1420916:AU14_RS07460
uniprot id: W5YPZ2
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1420916:AU14 RS16780
gene id: 1420916:AU14_RS16780
uniprot id: W5YTA0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1420916:AU14 RS04030
gene id: 1420916:AU14_RS04030
uniprot id: W5YNR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1420916:AU14 RS13070
gene id: 1420916:AU14_RS13070
uniprot id: W5YK46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1420916:AU14 RS02970
gene id: 1420916:AU14_RS02970
uniprot id: W5YFM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS18000
gene id: 1420916:AU14_RS18000
uniprot id: W5YKS0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1420916:AU14 RS06255
gene id: 1420916:AU14_RS06255
uniprot id: W5YGV2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1420916:AU14 RS12735
gene id: 1420916:AU14_RS12735
uniprot id: W5YRS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1420916:AU14 RS09540
gene id: 1420916:AU14_RS09540
uniprot id: W5YIC2
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS00485
gene id: 1420916:AU14_RS00485
uniprot id: W5YF40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1420916:AU14 RS15555
gene id: 1420916:AU14_RS15555
uniprot id: W5YKF7
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1420916:AU14 RS08295
gene id: 1420916:AU14_RS08295
uniprot id: W5YHF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1420916:AU14 RS07790
gene id: 1420916:AU14_RS07790
uniprot id: W5YHL4
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1420916:AU14 RS13060
gene id: 1420916:AU14_RS13060
uniprot id: W5YJ39
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1420916:AU14 RS06090
gene id: 1420916:AU14_RS06090
uniprot id: W5YHQ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1420916:AU14 RS15395
gene id: 1420916:AU14_RS15395
uniprot id: W5YKY8
names: Similarity
messages: Belongs to the TPP enzyme family.

1420916:AU14 RS12815
gene id: 1420916:AU14_RS12815
uniprot id: W5YJF2
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1420916:AU14 RS14570
gene id: 1420916:AU14_RS14570
uniprot id: W5YJQ1
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1420916:AU14 RS04005
gene id: 1420916:AU14_RS04005
uniprot id: W5YGU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1420916:AU14 RS02180
gene id: 1420916:AU14_RS02180
uniprot id: W5YFF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS02510
gene id: 1420916:AU14_RS02510
uniprot id: W5YFT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1420916:AU14 RS09435
gene id: 1420916:AU14_RS09435
uniprot id: W5YHV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS03060
gene id: 1420916:AU14_RS03060
uniprot id: W5YGK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1420916:AU14 RS08635
gene id: 1420916:AU14_RS08635
uniprot id: W5YHX9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1420916:AU14 RS07095
gene id: 1420916:AU14_RS07095
uniprot id: W5YHJ7
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1420916:AU14 RS07305
gene id: 1420916:AU14_RS07305
uniprot id: W5YI52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS13960
gene id: 1420916:AU14_RS13960
uniprot id: W5YJI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1420916:AU14 RS15940
gene id: 1420916:AU14_RS15940
uniprot id: W5YKI7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1420916:AU14 RS13610
gene id: 1420916:AU14_RS13610
uniprot id: W5YJR5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1420916:AU14 RS01410
gene id: 1420916:AU14_RS01410
uniprot id: W5YMU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1420916:AU14 RS02460
gene id: 1420916:AU14_RS02460
uniprot id: W5YN95
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1420916:AU14 RS18565
gene id: 1420916:AU14_RS18565
uniprot id: W5YFJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS01425
gene id: 1420916:AU14_RS01425
uniprot id: W5YFN8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1420916:AU14 RS07610
gene id: 1420916:AU14_RS07610
uniprot id: W5YHN9
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS06400
gene id: 1420916:AU14_RS06400
uniprot id: W5YGW3
names: Similarity
messages: Belongs to the MotB family.

1420916:AU14 RS02995
gene id: 1420916:AU14_RS02995
uniprot id: W5YG76
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1420916:AU14 RS04510
gene id: 1420916:AU14_RS04510
uniprot id: W5YG30
names: Subcellular Location Annotation
messages: Nucleus

1420916:AU14 RS05005
gene id: 1420916:AU14_RS05005
uniprot id: W5YGA2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1420916:AU14 RS16475
gene id: 1420916:AU14_RS16475
uniprot id: W5YKQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1420916:AU14 RS13125
gene id: 1420916:AU14_RS13125
uniprot id: W5YK59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1420916:AU14 RS00685
gene id: 1420916:AU14_RS00685
uniprot id: W5YFG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1420916:AU14 RS10995
gene id: 1420916:AU14_RS10995
uniprot id: W5YIU0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1420916:AU14 RS09280
gene id: 1420916:AU14_RS09280
uniprot id: W5YHU2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1420916:AU14 RS10390
gene id: 1420916:AU14_RS10390
uniprot id: W5YI95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1420916:AU14 RS13025
gene id: 1420916:AU14_RS13025
uniprot id: W5YJH9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1420916:AU14 RS03065
gene id: 1420916:AU14_RS03065
uniprot id: W5YG84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS01345
gene id: 1420916:AU14_RS01345
uniprot id: W5YF31
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS12240
gene id: 1420916:AU14_RS12240
uniprot id: W5YIS9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1420916:AU14 RS14820
gene id: 1420916:AU14_RS14820
uniprot id: W5YK47
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS01510
gene id: 1420916:AU14_RS01510
uniprot id: W5YFP7
names: Similarity
messages: Belongs to the peptidase S49 family.

1420916:AU14 RS08860
gene id: 1420916:AU14_RS08860
uniprot id: W5YI13
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1420916:AU14 RS13600
gene id: 1420916:AU14_RS13600
uniprot id: W5YS57
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1420916:AU14 RS16620
gene id: 1420916:AU14_RS16620
uniprot id: W5YT79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1420916:AU14 RS17970
gene id: 1420916:AU14_RS17970
uniprot id: W5YKR4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1420916:AU14 RS03685
gene id: 1420916:AU14_RS03685
uniprot id: W5YGQ8
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS03000
gene id: 1420916:AU14_RS03000
uniprot id: W5YFZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1420916:AU14 RS06070
gene id: 1420916:AU14_RS06070
uniprot id: W5YH90
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS08940
gene id: 1420916:AU14_RS08940
uniprot id: W5YHP3
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1420916:AU14 RS13000
gene id: 1420916:AU14_RS13000
uniprot id: W5YJH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1420916:AU14 RS18120
gene id: 1420916:AU14_RS18120
uniprot id: W5YKW6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1420916:AU14 RS06775
gene id: 1420916:AU14_RS06775
uniprot id: W5YHG7
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1420916:AU14 RS07605
gene id: 1420916:AU14_RS07605
uniprot id: W5YI85
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS05695
gene id: 1420916:AU14_RS05695
uniprot id: W5YPB0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1420916:AU14 RS00665
gene id: 1420916:AU14_RS00665
uniprot id: W5YF61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1420916:AU14 RS07060
gene id: 1420916:AU14_RS07060
uniprot id: W5YI20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS07800
gene id: 1420916:AU14_RS07800
uniprot id: W5YQ32
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1420916:AU14 RS17540
gene id: 1420916:AU14_RS17540
uniprot id: W5YKK8
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1420916:AU14 RS07425
gene id: 1420916:AU14_RS07425
uniprot id: W5YI64
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1420916:AU14 RS01575
gene id: 1420916:AU14_RS01575
uniprot id: W5YFF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1420916:AU14 RS11235
gene id: 1420916:AU14_RS11235
uniprot id: W5YIW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1420916:AU14 RS15315
gene id: 1420916:AU14_RS15315
uniprot id: W5YKY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1420916:AU14 RS11020
gene id: 1420916:AU14_RS11020
uniprot id: W5YIU9
names: Similarity
messages: Belongs to the thioredoxin family.

1420916:AU14 RS15915
gene id: 1420916:AU14_RS15915
uniprot id: W5YT03
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS13740
gene id: 1420916:AU14_RS13740
uniprot id: W5YJD0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1420916:AU14 RS04870
gene id: 1420916:AU14_RS04870
uniprot id: W5YGR8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS13555
gene id: 1420916:AU14_RS13555
uniprot id: W5YJQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1420916:AU14 RS13440
gene id: 1420916:AU14_RS13440
uniprot id: W5YJN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1420916:AU14 RS14220
gene id: 1420916:AU14_RS14220
uniprot id: W5YSH5
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1420916:AU14 RS00895
gene id: 1420916:AU14_RS00895
uniprot id: W5YFQ4
names: Similarity
messages: Belongs to the PrpD family.

1420916:AU14 RS08520
gene id: 1420916:AU14_RS08520
uniprot id: W5YQC0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1420916:AU14 RS14135
gene id: 1420916:AU14_RS14135
uniprot id: W5YJY2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1420916:AU14 RS12500
gene id: 1420916:AU14_RS12500
uniprot id: W5YJA4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1420916:AU14 RS09545
gene id: 1420916:AU14_RS09545
uniprot id: W5YIA8
names: Similarity
messages: Belongs to the UPF0178 family.

1420916:AU14 RS00670
gene id: 1420916:AU14_RS00670
uniprot id: W5YEU7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1420916:AU14 RS11355
gene id: 1420916:AU14_RS11355
uniprot id: W5YII2
names: Cofactor
messages: Probably binds two magnesium or manganese ions per subunit.

1420916:AU14 RS02865
gene id: 1420916:AU14_RS02865
uniprot id: W5YND5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1420916:AU14 RS01330
gene id: 1420916:AU14_RS01330
uniprot id: W5YFV4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1420916:AU14 RS06305
gene id: 1420916:AU14_RS06305
uniprot id: W5YH58
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1420916:AU14 RS13565
gene id: 1420916:AU14_RS13565
uniprot id: W5YJA5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1420916:AU14 RS08715
gene id: 1420916:AU14_RS08715
uniprot id: W5YIL4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1420916:AU14 RS10485
gene id: 1420916:AU14_RS10485
uniprot id: W5YIP6
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS13230
gene id: 1420916:AU14_RS13230
uniprot id: W5YK79
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1420916:AU14 RS12285
gene id: 1420916:AU14_RS12285
uniprot id: W5YJU8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1420916:AU14 RS17660
gene id: 1420916:AU14_RS17660
uniprot id: W5YTJ2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1420916:AU14 RS02160
gene id: 1420916:AU14_RS02160
uniprot id: W5YGA3
names: Similarity
messages: Belongs to the GST superfamily.

1420916:AU14 RS07430
gene id: 1420916:AU14_RS07430
uniprot id: W5YHM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1420916:AU14 RS15875
gene id: 1420916:AU14_RS15875
uniprot id: W5YKJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS15595
gene id: 1420916:AU14_RS15595
uniprot id: W5YKE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1420916:AU14 RS12755
gene id: 1420916:AU14_RS12755
uniprot id: W5YJE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1420916:AU14 RS11655
gene id: 1420916:AU14_RS11655
uniprot id: W5YJ22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1420916:AU14 RS18155
gene id: 1420916:AU14_RS18155
uniprot id: W5YKY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1420916:AU14 RS03535
gene id: 1420916:AU14_RS03535
uniprot id: W5YG41
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

1420916:AU14 RS07715
gene id: 1420916:AU14_RS07715
uniprot id: W5YH77
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1420916:AU14 RS04055
gene id: 1420916:AU14_RS04055
uniprot id: W5YFX4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1420916:AU14 RS08660
gene id: 1420916:AU14_RS08660
uniprot id: W5YHY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1420916:AU14 RS16385
gene id: 1420916:AU14_RS16385
uniprot id: W5YL84
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS11475
gene id: 1420916:AU14_RS11475
uniprot id: W5YJL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1420916:AU14 RS06010
gene id: 1420916:AU14_RS06010
uniprot id: W5YHP8
names: Similarity
messages: Belongs to the IMPACT family.

1420916:AU14 RS02775
gene id: 1420916:AU14_RS02775
uniprot id: W5YFK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS14025
gene id: 1420916:AU14_RS14025
uniprot id: W5YJX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS00555
gene id: 1420916:AU14_RS00555
uniprot id: W5YET2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1420916:AU14 RS02455
gene id: 1420916:AU14_RS02455
uniprot id: W5YFH6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1420916:AU14 RS16070
gene id: 1420916:AU14_RS16070
uniprot id: W5YKM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1420916:AU14 RS14280
gene id: 1420916:AU14_RS14280
uniprot id: W5YJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS03390
gene id: 1420916:AU14_RS03390
uniprot id: W5YGA5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1420916:AU14 RS01455
gene id: 1420916:AU14_RS01455
uniprot id: W5YMV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS11665
gene id: 1420916:AU14_RS11665
uniprot id: W5YJ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1420916:AU14 RS07950
gene id: 1420916:AU14_RS07950
uniprot id: W5YHU0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1420916:AU14 RS04955
gene id: 1420916:AU14_RS04955
uniprot id: W5YGS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS04025
gene id: 1420916:AU14_RS04025
uniprot id: W5YFW9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1420916:AU14 RS13950
gene id: 1420916:AU14_RS13950
uniprot id: W5YJX0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1420916:AU14 RS11630
gene id: 1420916:AU14_RS11630
uniprot id: W5YIK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1420916:AU14 RS09715
gene id: 1420916:AU14_RS09715
uniprot id: W5YID6
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1420916:AU14 RS14670
gene id: 1420916:AU14_RS14670
uniprot id: W5YKS9
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS00645
gene id: 1420916:AU14_RS00645
uniprot id: W5YMK7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS13615
gene id: 1420916:AU14_RS13615
uniprot id: W5YJR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1420916:AU14 RS04190
gene id: 1420916:AU14_RS04190
uniprot id: W5YNS9
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

1420916:AU14 RS08460
gene id: 1420916:AU14_RS08460
uniprot id: W5YHI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1420916:AU14 RS02640
gene id: 1420916:AU14_RS02640
uniprot id: W5YG44
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1420916:AU14 RS14415
gene id: 1420916:AU14_RS14415
uniprot id: W5YK22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1420916:AU14 RS13915
gene id: 1420916:AU14_RS13915
uniprot id: W5YJF6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1420916:AU14 RS08115
gene id: 1420916:AU14_RS08115
uniprot id: W5YIE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1420916:AU14 RS12935
gene id: 1420916:AU14_RS12935
uniprot id: W5YK10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1420916:AU14 RS07590
gene id: 1420916:AU14_RS07590
uniprot id: W5YH60
names: Similarity
messages: Belongs to the histone deacetylase family.

1420916:AU14 RS00615
gene id: 1420916:AU14_RS00615
uniprot id: W5YFM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1420916:AU14 RS03680
gene id: 1420916:AU14_RS03680
uniprot id: W5YNM6
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1420916:AU14 RS01630
gene id: 1420916:AU14_RS01630
uniprot id: W5YFG5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1420916:AU14 RS05670
gene id: 1420916:AU14_RS05670
uniprot id: W5YHG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1420916:AU14 RS07860
gene id: 1420916:AU14_RS07860
uniprot id: W5YH95
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1420916:AU14 RS13545
gene id: 1420916:AU14_RS13545
uniprot id: W5YS47
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1420916:AU14 RS11675
gene id: 1420916:AU14_RS11675
uniprot id: W5YIL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1420916:AU14 RS14060
gene id: 1420916:AU14_RS14060
uniprot id: W5YSF6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1420916:AU14 RS15105
gene id: 1420916:AU14_RS15105
uniprot id: W5YSQ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1420916:AU14 RS03425
gene id: 1420916:AU14_RS03425
uniprot id: W5YGM9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1420916:AU14 RS16815
gene id: 1420916:AU14_RS16815
uniprot id: W5YMV5
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.

1420916:AU14 RS14560
gene id: 1420916:AU14_RS14560
uniprot id: W5YK39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1420916:AU14 RS13275
gene id: 1420916:AU14_RS13275
uniprot id: W5YK87
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1420916:AU14 RS15260
gene id: 1420916:AU14_RS15260
uniprot id: W5YKX6
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

1420916:AU14 RS09010
gene id: 1420916:AU14_RS09010
uniprot id: W5YHQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1420916:AU14 RS10480
gene id: 1420916:AU14_RS10480
uniprot id: W5YJD3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS10325
gene id: 1420916:AU14_RS10325
uniprot id: W5YIM3
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS15050
gene id: 1420916:AU14_RS15050
uniprot id: W5YSP9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1420916:AU14 RS18140
gene id: 1420916:AU14_RS18140
uniprot id: W5YLG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1420916:AU14 RS11290
gene id: 1420916:AU14_RS11290
uniprot id: W5YJJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1420916:AU14 RS14170
gene id: 1420916:AU14_RS14170
uniprot id: W5YJL6
names: Similarity
messages: Belongs to the peptidase S49 family.

1420916:AU14 RS08640
gene id: 1420916:AU14_RS08640
uniprot id: W5YHK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1420916:AU14 RS09325
gene id: 1420916:AU14_RS09325
uniprot id: W5YHU8
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1420916:AU14 RS02095
gene id: 1420916:AU14_RS02095
uniprot id: W5YFP4
names: Similarity
messages: Belongs to the thioredoxin family.

1420916:AU14 RS08730
gene id: 1420916:AU14_RS08730
uniprot id: W5YI25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1420916:AU14 RS07615
gene id: 1420916:AU14_RS07615
uniprot id: W5YHJ1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1420916:AU14 RS10320
gene id: 1420916:AU14_RS10320
uniprot id: W5YIN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1420916:AU14 RS16535
gene id: 1420916:AU14_RS16535
uniprot id: W5YKU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1420916:AU14 RS17880
gene id: 1420916:AU14_RS17880
uniprot id: W5YLP5
names: Cofactor
messages: Can also use Mn(2+) ion.

1420916:AU14 RS07660
gene id: 1420916:AU14_RS07660
uniprot id: W5YH68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1420916:AU14 RS08820
gene id: 1420916:AU14_RS08820
uniprot id: W5YIN2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1420916:AU14 RS03590
gene id: 1420916:AU14_RS03590
uniprot id: W5YG51
names: Similarity
messages: Belongs to the PhzF family.

1420916:AU14 RS13200
gene id: 1420916:AU14_RS13200
uniprot id: W5YK70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1420916:AU14 RS16295
gene id: 1420916:AU14_RS16295
uniprot id: W5YT39
names: Similarity
messages: Belongs to the BolA/IbaG family.

1420916:AU14 RS10550
gene id: 1420916:AU14_RS10550
uniprot id: W5YIP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1420916:AU14 RS01720
gene id: 1420916:AU14_RS01720
uniprot id: W5YG19
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1420916:AU14 RS10920
gene id: 1420916:AU14_RS10920
uniprot id: W5YJH0
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1420916:AU14 RS03045
gene id: 1420916:AU14_RS03045
uniprot id: W5YFM6
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1420916:AU14 RS01965
gene id: 1420916:AU14_RS01965
uniprot id: W5YFD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS12085
gene id: 1420916:AU14_RS12085
uniprot id: W5YJT5
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1420916:AU14 RS06380
gene id: 1420916:AU14_RS06380
uniprot id: W5YHD0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1420916:AU14 RS03995
gene id: 1420916:AU14_RS03995
uniprot id: W5YNQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1420916:AU14 RS07595
gene id: 1420916:AU14_RS07595
uniprot id: W5YQ08
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1420916:AU14 RS02600
gene id: 1420916:AU14_RS02600
uniprot id: W5YNA7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS14655
gene id: 1420916:AU14_RS14655
uniprot id: W5YK26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1420916:AU14 RS08415
gene id: 1420916:AU14_RS08415
uniprot id: W5YIH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1420916:AU14 RS08560
gene id: 1420916:AU14_RS08560
uniprot id: W5YHJ5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1420916:AU14 RS09175
gene id: 1420916:AU14_RS09175
uniprot id: W5YI55
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1420916:AU14 RS12415
gene id: 1420916:AU14_RS12415
uniprot id: W5YJV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1420916:AU14 RS13195
gene id: 1420916:AU14_RS13195
uniprot id: W5YS00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1420916:AU14 RS10015
gene id: 1420916:AU14_RS10015
uniprot id: W5YIK1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1420916:AU14 RS04660
gene id: 1420916:AU14_RS04660
uniprot id: W5YH23
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1420916:AU14 RS11890
gene id: 1420916:AU14_RS11890
uniprot id: W5YIN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1420916:AU14 RS01715
gene id: 1420916:AU14_RS01715
uniprot id: W5YMY4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1420916:AU14 RS19410
gene id: 1420916:AU14_RS19410
uniprot id: W5YKG3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1420916:AU14 RS10160
gene id: 1420916:AU14_RS10160
uniprot id: W5YIL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1420916:AU14 RS17730
gene id: 1420916:AU14_RS17730
uniprot id: W5YL80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1420916:AU14 RS11395
gene id: 1420916:AU14_RS11395
uniprot id: W5YRD6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS13445
gene id: 1420916:AU14_RS13445
uniprot id: W5YJN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1420916:AU14 RS02355
gene id: 1420916:AU14_RS02355
uniprot id: W5YFS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1420916:AU14 RS17355
gene id: 1420916:AU14_RS17355
uniprot id: W5YKJ2
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1420916:AU14 RS00570
gene id: 1420916:AU14_RS00570
uniprot id: W5YFF0
names: Similarity
messages: Belongs to the UPF0434 family.

1420916:AU14 RS15640
gene id: 1420916:AU14_RS15640
uniprot id: W5YK03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1420916:AU14 RS02330
gene id: 1420916:AU14_RS02330
uniprot id: W5YFG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS08410
gene id: 1420916:AU14_RS08410
uniprot id: W5YQA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1420916:AU14 RS06330
gene id: 1420916:AU14_RS06330
uniprot id: W5YPM8
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS16570
gene id: 1420916:AU14_RS16570
uniprot id: W5YKB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1420916:AU14 RS14015
gene id: 1420916:AU14_RS14015
uniprot id: W5YKM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1420916:AU14 RS12775
gene id: 1420916:AU14_RS12775
uniprot id: W5YJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1420916:AU14 RS08645
gene id: 1420916:AU14_RS08645
uniprot id: W5YQD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1420916:AU14 RS17405
gene id: 1420916:AU14_RS17405
uniprot id: W5YKJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS02630
gene id: 1420916:AU14_RS02630
uniprot id: W5YNB2
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1420916:AU14 RS11980
gene id: 1420916:AU14_RS11980
uniprot id: W5YJS1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1420916:AU14 RS16660
gene id: 1420916:AU14_RS16660
uniprot id: W5YKV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1420916:AU14 RS09090
gene id: 1420916:AU14_RS09090
uniprot id: W5YHR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1420916:AU14 RS03215
gene id: 1420916:AU14_RS03215
uniprot id: W5YG92
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1420916:AU14 RS16775
gene id: 1420916:AU14_RS16775
uniprot id: W5YKE1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1420916:AU14 RS12975
gene id: 1420916:AU14_RS12975
uniprot id: W5YJH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1420916:AU14 RS01460
gene id: 1420916:AU14_RS01460
uniprot id: W5YFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1420916:AU14 RS02065
gene id: 1420916:AU14_RS02065
uniprot id: W5YLQ2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1420916:AU14 RS17140
gene id: 1420916:AU14_RS17140
uniprot id: W5YTC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1420916:AU14 RS14640
gene id: 1420916:AU14_RS14640
uniprot id: W5YKS6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1420916:AU14 RS05230
gene id: 1420916:AU14_RS05230
uniprot id: W5YH98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS12065
gene id: 1420916:AU14_RS12065
uniprot id: W5YIR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1420916:AU14 RS14145
gene id: 1420916:AU14_RS14145
uniprot id: W5YJL2
names: Similarity
messages: Belongs to the fabD family.

1420916:AU14 RS02210
gene id: 1420916:AU14_RS02210
uniprot id: W5YGA7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1420916:AU14 RS06065
gene id: 1420916:AU14_RS06065
uniprot id: W5YHQ1
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS04310
gene id: 1420916:AU14_RS04310
uniprot id: W5YGK9
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1420916:AU14 RS15060
gene id: 1420916:AU14_RS15060
uniprot id: W5YKA0
names: Similarity
messages: Belongs to the histone deacetylase family.

1420916:AU14 RS12960
gene id: 1420916:AU14_RS12960
uniprot id: W5YRV8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1420916:AU14 RS03385
gene id: 1420916:AU14_RS03385
uniprot id: W5YGM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1420916:AU14 RS15125
gene id: 1420916:AU14_RS15125
uniprot id: W5YKW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1420916:AU14 RS08555
gene id: 1420916:AU14_RS08555
uniprot id: W5YHW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1420916:AU14 RS09160
gene id: 1420916:AU14_RS09160
uniprot id: W5YIT7
names: Similarity
messages: Belongs to the threonine synthase family.

1420916:AU14 RS05720
gene id: 1420916:AU14_RS05720
uniprot id: W5YH15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1420916:AU14 RS03040
gene id: 1420916:AU14_RS03040
uniprot id: W5YG01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1420916:AU14 RS18020
gene id: 1420916:AU14_RS18020
uniprot id: W5YLA4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1420916:AU14 RS06450
gene id: 1420916:AU14_RS06450
uniprot id: W5YPN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1420916:AU14 RS12045
gene id: 1420916:AU14_RS12045
uniprot id: W5YJ63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1420916:AU14 RS05030
gene id: 1420916:AU14_RS05030
uniprot id: W5YGA8
names: Similarity
messages: Belongs to the YjdM family.

1420916:AU14 RS13640
gene id: 1420916:AU14_RS13640
uniprot id: W5YS62
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1420916:AU14 RS03775
gene id: 1420916:AU14_RS03775
uniprot id: W5YNN5
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1420916:AU14 RS06610
gene id: 1420916:AU14_RS06610
uniprot id: W5YHW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1420916:AU14 RS09255
gene id: 1420916:AU14_RS09255
uniprot id: W5YQM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1420916:AU14 RS04220
gene id: 1420916:AU14_RS04220
uniprot id: W5YGD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1420916:AU14 RS01335
gene id: 1420916:AU14_RS01335
uniprot id: W5YFM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1420916:AU14 RS06845
gene id: 1420916:AU14_RS06845
uniprot id: W5YHA6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1420916:AU14 RS08275
gene id: 1420916:AU14_RS08275
uniprot id: W5YQ88
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1420916:AU14 RS12990
gene id: 1420916:AU14_RS12990
uniprot id: W5YK28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1420916:AU14 RS16225
gene id: 1420916:AU14_RS16225
uniprot id: W5YL66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1420916:AU14 RS13845
gene id: 1420916:AU14_RS13845
uniprot id: W5YS93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1420916:AU14 RS14425
gene id: 1420916:AU14_RS14425
uniprot id: W5YJN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1420916:AU14 RS14535
gene id: 1420916:AU14_RS14535
uniprot id: W5YSK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS11585
gene id: 1420916:AU14_RS11585
uniprot id: W5YIK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1420916:AU14 RS12195
gene id: 1420916:AU14_RS12195
uniprot id: W5YRL9
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS02625
gene id: 1420916:AU14_RS02625
uniprot id: W5YFJ0
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1420916:AU14 RS14950
gene id: 1420916:AU14_RS14950
uniprot id: W5YK61
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS14685
gene id: 1420916:AU14_RS14685
uniprot id: W5YJR3
names: Subcellular Location Annotation
messages: Cell inner membrane

1420916:AU14 RS16580
gene id: 1420916:AU14_RS16580
uniprot id: W5YLB1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1420916:AU14 RS00640
gene id: 1420916:AU14_RS00640
uniprot id: W5YEU2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1420916:AU14 RS05895
gene id: 1420916:AU14_RS05895
uniprot id: W5YPD9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS00675
gene id: 1420916:AU14_RS00675
uniprot id: W5YML2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1420916:AU14 RS14800
gene id: 1420916:AU14_RS14800
uniprot id: W5YSM6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS11990
gene id: 1420916:AU14_RS11990
uniprot id: W5YJ52
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1420916:AU14 RS11305
gene id: 1420916:AU14_RS11305
uniprot id: W5YIX7
names: Similarity
messages: Belongs to the GSP E family.

1420916:AU14 RS00230
gene id: 1420916:AU14_RS00230
uniprot id: W5YFA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1420916:AU14 RS08755
gene id: 1420916:AU14_RS08755
uniprot id: W5YI29
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1420916:AU14 RS06695
gene id: 1420916:AU14_RS06695
uniprot id: W5YGY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1420916:AU14 RS06355
gene id: 1420916:AU14_RS06355
uniprot id: W5YGV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1420916:AU14 RS07685
gene id: 1420916:AU14_RS07685
uniprot id: W5YH73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1420916:AU14 RS11285
gene id: 1420916:AU14_RS11285
uniprot id: W5YRC2
names: Similarity
messages: Belongs to the YggT family.

1420916:AU14 RS01310
gene id: 1420916:AU14_RS01310
uniprot id: W5YFB8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1420916:AU14 RS08885
gene id: 1420916:AU14_RS08885
uniprot id: W5YI43
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1420916:AU14 RS00490
gene id: 1420916:AU14_RS00490
uniprot id: W5YES7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1420916:AU14 RS18125
gene id: 1420916:AU14_RS18125
uniprot id: W5YTU5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1420916:AU14 RS07525
gene id: 1420916:AU14_RS07525
uniprot id: W5YHN3
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

1420916:AU14 RS13945
gene id: 1420916:AU14_RS13945
uniprot id: W5YJX2
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

1420916:AU14 RS00445
gene id: 1420916:AU14_RS00445
uniprot id: W5YFD5
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1420916:AU14 RS08420
gene id: 1420916:AU14_RS08420
uniprot id: W5YHZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1420916:AU14 RS00390
gene id: 1420916:AU14_RS00390
uniprot id: W5YF24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS14105
gene id: 1420916:AU14_RS14105
uniprot id: W5YJK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS13490
gene id: 1420916:AU14_RS13490
uniprot id: W5YJ93
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1420916:AU14 RS13625
gene id: 1420916:AU14_RS13625
uniprot id: W5YJB7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1420916:AU14 RS00110
gene id: 1420916:AU14_RS00110
uniprot id: W5YMD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS16770
gene id: 1420916:AU14_RS16770
uniprot id: W5YKU8
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS13715
gene id: 1420916:AU14_RS13715
uniprot id: W5YJS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1420916:AU14 RS03920
gene id: 1420916:AU14_RS03920
uniprot id: W5YNQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1420916:AU14 RS08505
gene id: 1420916:AU14_RS08505
uniprot id: W5YHI9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1420916:AU14 RS10990
gene id: 1420916:AU14_RS10990
uniprot id: W5YIU4
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

1420916:AU14 RS04705
gene id: 1420916:AU14_RS04705
uniprot id: W5YG59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS08655
gene id: 1420916:AU14_RS08655
uniprot id: W5YI19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1420916:AU14 RS09000
gene id: 1420916:AU14_RS09000
uniprot id: W5YI53
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1420916:AU14 RS14575
gene id: 1420916:AU14_RS14575
uniprot id: W5YSK6
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS10570
gene id: 1420916:AU14_RS10570
uniprot id: W5YIQ6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1420916:AU14 RS12795
gene id: 1420916:AU14_RS12795
uniprot id: W5YJ00
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

1420916:AU14 RS09440
gene id: 1420916:AU14_RS09440
uniprot id: W5YQP3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1420916:AU14 RS00655
gene id: 1420916:AU14_RS00655
uniprot id: W5YFM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1420916:AU14 RS00370
gene id: 1420916:AU14_RS00370
uniprot id: W5YMG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

1420916:AU14 RS16200
gene id: 1420916:AU14_RS16200
uniprot id: W5YKN8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS11375
gene id: 1420916:AU14_RS11375
uniprot id: W5YIZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1420916:AU14 RS14525
gene id: 1420916:AU14_RS14525
uniprot id: W5YJP8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1420916:AU14 RS02350
gene id: 1420916:AU14_RS02350
uniprot id: W5YG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1420916:AU14 RS00680
gene id: 1420916:AU14_RS00680
uniprot id: W5YFM7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1420916:AU14 RS15590
gene id: 1420916:AU14_RS15590
uniprot id: W5YKG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1420916:AU14 RS08360
gene id: 1420916:AU14_RS08360
uniprot id: W5YHU3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1420916:AU14 RS02340
gene id: 1420916:AU14_RS02340
uniprot id: W5YGC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS17795
gene id: 1420916:AU14_RS17795
uniprot id: W5YTK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MerP family.
messages: Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
messages: Monomer.
messages: Periplasm

1420916:AU14 RS13395
gene id: 1420916:AU14_RS13395
uniprot id: W5YJN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1420916:AU14 RS13910
gene id: 1420916:AU14_RS13910
uniprot id: W5YJU9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1420916:AU14 RS13890
gene id: 1420916:AU14_RS13890
uniprot id: W5YKI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1420916:AU14 RS13020
gene id: 1420916:AU14_RS13020
uniprot id: W5YJH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1420916:AU14 RS08975
gene id: 1420916:AU14_RS08975
uniprot id: W5YI26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS16210
gene id: 1420916:AU14_RS16210
uniprot id: W5YK67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS06215
gene id: 1420916:AU14_RS06215
uniprot id: W5YHS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1420916:AU14 RS09200
gene id: 1420916:AU14_RS09200
uniprot id: W5YI61
names: Function
names: Similarity
messages: An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
messages: Belongs to the SdhE FAD assembly factor family.

1420916:AU14 RS08830
gene id: 1420916:AU14_RS08830
uniprot id: W5YI09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS11835
gene id: 1420916:AU14_RS11835
uniprot id: W5YJ34
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1420916:AU14 RS04665
gene id: 1420916:AU14_RS04665
uniprot id: W5YGP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1420916:AU14 RS06950
gene id: 1420916:AU14_RS06950
uniprot id: W5YH06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1420916:AU14 RS17785
gene id: 1420916:AU14_RS17785
uniprot id: W5YKN7
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

1420916:AU14 RS04595
gene id: 1420916:AU14_RS04595
uniprot id: W5YH17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1420916:AU14 RS13065
gene id: 1420916:AU14_RS13065
uniprot id: W5YRX8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1420916:AU14 RS08195
gene id: 1420916:AU14_RS08195
uniprot id: W5YHE1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1420916:AU14 RS15225
gene id: 1420916:AU14_RS15225
uniprot id: W5YSR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1420916:AU14 RS11700
gene id: 1420916:AU14_RS11700
uniprot id: W5YJ27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1420916:AU14 RS14215
gene id: 1420916:AU14_RS14215
uniprot id: W5YJL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1420916:AU14 RS00385
gene id: 1420916:AU14_RS00385
uniprot id: W5YFC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1420916:AU14 RS16380
gene id: 1420916:AU14_RS16380
uniprot id: W5YT46
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1420916:AU14 RS12855
gene id: 1420916:AU14_RS12855
uniprot id: W5YJ10
names: Similarity
messages: Belongs to the type III secretion exporter family.

1420916:AU14 RS04275
gene id: 1420916:AU14_RS04275
uniprot id: W5YNU0
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1420916:AU14 RS10125
gene id: 1420916:AU14_RS10125
uniprot id: W5YR14
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1420916:AU14 RS13550
gene id: 1420916:AU14_RS13550
uniprot id: W5YKC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1420916:AU14 RS11025
gene id: 1420916:AU14_RS11025
uniprot id: W5YIU5
names: Similarity
messages: Belongs to the MoaD family.

1420916:AU14 RS04235
gene id: 1420916:AU14_RS04235
uniprot id: W5YNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS16375
gene id: 1420916:AU14_RS16375
uniprot id: W5YK86
names: Similarity
messages: Belongs to the aspartokinase family.

1420916:AU14 RS09955
gene id: 1420916:AU14_RS09955
uniprot id: W5YJ85
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS07725
gene id: 1420916:AU14_RS07725
uniprot id: W5YIA1
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS07665
gene id: 1420916:AU14_RS07665
uniprot id: W5YQ17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

1420916:AU14 RS05950
gene id: 1420916:AU14_RS05950
uniprot id: W5YH57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1420916:AU14 RS04385
gene id: 1420916:AU14_RS04385
uniprot id: W5YGZ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1420916:AU14 RS15800
gene id: 1420916:AU14_RS15800
uniprot id: W5YK18
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1420916:AU14 RS13050
gene id: 1420916:AU14_RS13050
uniprot id: W5YJI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1420916:AU14 RS03915
gene id: 1420916:AU14_RS03915
uniprot id: W5YFW1
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1420916:AU14 RS00430
gene id: 1420916:AU14_RS00430
uniprot id: W5YMI1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS04800
gene id: 1420916:AU14_RS04800
uniprot id: W5YP05
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1420916:AU14 RS16190
gene id: 1420916:AU14_RS16190
uniprot id: W5YT27
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1420916:AU14 RS15130
gene id: 1420916:AU14_RS15130
uniprot id: W5YKA5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1420916:AU14 RS08425
gene id: 1420916:AU14_RS08425
uniprot id: W5YHV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1420916:AU14 RS16010
gene id: 1420916:AU14_RS16010
uniprot id: W5YT12
names: Similarity
messages: Belongs to the glutamate synthase family.

1420916:AU14 RS09355
gene id: 1420916:AU14_RS09355
uniprot id: W5YIW2
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS06360
gene id: 1420916:AU14_RS06360
uniprot id: W5YPN1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1420916:AU14 RS16805
gene id: 1420916:AU14_RS16805
uniprot id: W5YM07
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.

1420916:AU14 RS06765
gene id: 1420916:AU14_RS06765
uniprot id: W5YHY8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1420916:AU14 RS11480
gene id: 1420916:AU14_RS11480
uniprot id: W5YJ02
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1420916:AU14 RS06740
gene id: 1420916:AU14_RS06740
uniprot id: W5YGZ1
names: Similarity
messages: Belongs to the SCO1/2 family.

1420916:AU14 RS07795
gene id: 1420916:AU14_RS07795
uniprot id: W5YH86
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

1420916:AU14 RS13605
gene id: 1420916:AU14_RS13605
uniprot id: W5YKD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1420916:AU14 RS00560
gene id: 1420916:AU14_RS00560
uniprot id: W5YMJ5
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS07965
gene id: 1420916:AU14_RS07965
uniprot id: W5YHB1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1420916:AU14 RS07395
gene id: 1420916:AU14_RS07395
uniprot id: W5YH44
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1420916:AU14 RS00060
gene id: 1420916:AU14_RS00060
uniprot id: W5YEM1
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS09990
gene id: 1420916:AU14_RS09990
uniprot id: W5YR01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1420916:AU14 RS11385
gene id: 1420916:AU14_RS11385
uniprot id: W5YIY7
names: Similarity
messages: Belongs to the RutC family.

1420916:AU14 RS15230
gene id: 1420916:AU14_RS15230
uniprot id: W5YKX4
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1420916:AU14 RS11925
gene id: 1420916:AU14_RS11925
uniprot id: W5YJ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1420916:AU14 RS02765
gene id: 1420916:AU14_RS02765
uniprot id: W5YFW2
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1420916:AU14 RS12420
gene id: 1420916:AU14_RS12420
uniprot id: W5YJ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1420916:AU14 RS03830
gene id: 1420916:AU14_RS03830
uniprot id: W5YNP0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1420916:AU14 RS02825
gene id: 1420916:AU14_RS02825
uniprot id: W5YFK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1420916:AU14 RS00565
gene id: 1420916:AU14_RS00565
uniprot id: W5YFL4
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1420916:AU14 RS08170
gene id: 1420916:AU14_RS08170
uniprot id: W5YHD7
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1420916:AU14 RS11850
gene id: 1420916:AU14_RS11850
uniprot id: W5YJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1420916:AU14 RS04465
gene id: 1420916:AU14_RS04465
uniprot id: W5YNW2
names: Similarity
messages: Belongs to the thioester dehydratase family. FabA subfamily.

1420916:AU14 RS08735
gene id: 1420916:AU14_RS08735
uniprot id: W5YHZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1420916:AU14 RS11985
gene id: 1420916:AU14_RS11985
uniprot id: W5YJ54
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1420916:AU14 RS06645
gene id: 1420916:AU14_RS06645
uniprot id: W5YHF6
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS10075
gene id: 1420916:AU14_RS10075
uniprot id: W5YIJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1420916:AU14 RS17845
gene id: 1420916:AU14_RS17845
uniprot id: W5YTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS08665
gene id: 1420916:AU14_RS08665
uniprot id: W5YHK8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1420916:AU14 RS01170
gene id: 1420916:AU14_RS01170
uniprot id: W5YFS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1420916:AU14 RS09625
gene id: 1420916:AU14_RS09625
uniprot id: W5YHY2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1420916:AU14 RS03270
gene id: 1420916:AU14_RS03270
uniprot id: W5YG20
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1420916:AU14 RS05560
gene id: 1420916:AU14_RS05560
uniprot id: W5YP95
names: Similarity
messages: Belongs to the elongation factor P family.

1420916:AU14 RS12875
gene id: 1420916:AU14_RS12875
uniprot id: W5YJG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1420916:AU14 RS06125
gene id: 1420916:AU14_RS06125
uniprot id: W5YHR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1420916:AU14 RS08815
gene id: 1420916:AU14_RS08815
uniprot id: W5YQG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1420916:AU14 RS03010
gene id: 1420916:AU14_RS03010
uniprot id: W5YNG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1420916:AU14 RS15170
gene id: 1420916:AU14_RS15170
uniprot id: W5YKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS16250
gene id: 1420916:AU14_RS16250
uniprot id: W5YT34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1420916:AU14 RS13805
gene id: 1420916:AU14_RS13805
uniprot id: W5YS86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1420916:AU14 RS08380
gene id: 1420916:AU14_RS08380
uniprot id: W5YQA1
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1420916:AU14 RS16515
gene id: 1420916:AU14_RS16515
uniprot id: W5YT65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1420916:AU14 RS09850
gene id: 1420916:AU14_RS09850
uniprot id: W5YII9
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1420916:AU14 RS02080
gene id: 1420916:AU14_RS02080
uniprot id: W5YG93
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1420916:AU14 RS06625
gene id: 1420916:AU14_RS06625
uniprot id: W5YGY0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1420916:AU14 RS06225
gene id: 1420916:AU14_RS06225
uniprot id: W5YH49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1420916:AU14 RS01920
gene id: 1420916:AU14_RS01920
uniprot id: W5YFC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1420916:AU14 RS12780
gene id: 1420916:AU14_RS12780
uniprot id: W5YJE4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1420916:AU14 RS14775
gene id: 1420916:AU14_RS14775
uniprot id: W5YKU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1420916:AU14 RS06430
gene id: 1420916:AU14_RS06430
uniprot id: W5YHD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1420916:AU14 RS03540
gene id: 1420916:AU14_RS03540
uniprot id: W5YFR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1420916:AU14 RS11350
gene id: 1420916:AU14_RS11350
uniprot id: W5YIY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1420916:AU14 RS00605
gene id: 1420916:AU14_RS00605
uniprot id: W5YMK1
names: Subcellular Location Annotation
messages: Cytoplasm

1420916:AU14 RS16065
gene id: 1420916:AU14_RS16065
uniprot id: W5YL51
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1420916:AU14 RS01490
gene id: 1420916:AU14_RS01490
uniprot id: W5YF48
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1420916:AU14 RS01245
gene id: 1420916:AU14_RS01245
uniprot id: W5YMS1
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1420916:AU14 RS09590
gene id: 1420916:AU14_RS09590
uniprot id: W5YHX8
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1420916:AU14 RS09820
gene id: 1420916:AU14_RS09820
uniprot id: W5YII6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1420916:AU14 RS17755
gene id: 1420916:AU14_RS17755
uniprot id: W5YTK3
names: Similarity
messages: Belongs to the SCO1/2 family.

1420916:AU14 RS07010
gene id: 1420916:AU14_RS07010
uniprot id: W5YHC0
names: Similarity
messages: Belongs to the LOG family.

1420916:AU14 RS04710
gene id: 1420916:AU14_RS04710
uniprot id: W5YNZ5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1420916:AU14 RS01325
gene id: 1420916:AU14_RS01325
uniprot id: W5YMT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS12175
gene id: 1420916:AU14_RS12175
uniprot id: W5YJ70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1420916:AU14 RS16195
gene id: 1420916:AU14_RS16195
uniprot id: W5YL62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1420916:AU14 RS16715
gene id: 1420916:AU14_RS16715
uniprot id: W5YKD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1420916:AU14 RS14750
gene id: 1420916:AU14_RS14750
uniprot id: W5YKT8
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1420916:AU14 RS08060
gene id: 1420916:AU14_RS08060
uniprot id: W5YHP6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1420916:AU14 RS08010
gene id: 1420916:AU14_RS08010
uniprot id: W5YHU6
names: Similarity
messages: Belongs to the pirin family.

1420916:AU14 RS16895
gene id: 1420916:AU14_RS16895
uniprot id: W5YKV8
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: Single-chain monomer with multiple functions.

1420916:AU14 RS05860
gene id: 1420916:AU14_RS05860
uniprot id: W5YPD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1420916:AU14 RS09135
gene id: 1420916:AU14_RS09135
uniprot id: W5YI46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1420916:AU14 RS03250
gene id: 1420916:AU14_RS03250
uniprot id: W5YNH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1420916:AU14 RS18165
gene id: 1420916:AU14_RS18165
uniprot id: W5YLY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1420916:AU14 RS04010
gene id: 1420916:AU14_RS04010
uniprot id: W5YGH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1420916:AU14 RS13045
gene id: 1420916:AU14_RS13045
uniprot id: W5YJI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1420916:AU14 RS07030
gene id: 1420916:AU14_RS07030
uniprot id: W5YI15
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1420916:AU14 RS08365
gene id: 1420916:AU14_RS08365
uniprot id: W5YHG9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1420916:AU14 RS17855
gene id: 1420916:AU14_RS17855
uniprot id: W5YL77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1420916:AU14 RS08565
gene id: 1420916:AU14_RS08565
uniprot id: W5YQC6
names: Similarity
messages: Belongs to the DEAD box helicase family.

1420916:AU14 RS12465
gene id: 1420916:AU14_RS12465
uniprot id: W5YIV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1420916:AU14 RS11030
gene id: 1420916:AU14_RS11030
uniprot id: W5YIF5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1420916:AU14 RS03335
gene id: 1420916:AU14_RS03335
uniprot id: W5YG23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1420916:AU14 RS11995
gene id: 1420916:AU14_RS11995
uniprot id: W5YIQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS00635
gene id: 1420916:AU14_RS00635
uniprot id: W5YF55
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1420916:AU14 RS12510
gene id: 1420916:AU14_RS12510
uniprot id: W5YRP8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1420916:AU14 RS07875
gene id: 1420916:AU14_RS07875
uniprot id: W5YIC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1420916:AU14 RS18130
gene id: 1420916:AU14_RS18130
uniprot id: W5YLX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1420916:AU14 RS05295
gene id: 1420916:AU14_RS05295
uniprot id: W5YGX2
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1420916:AU14 RS13450
gene id: 1420916:AU14_RS13450
uniprot id: W5YJ87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1420916:AU14 RS05345
gene id: 1420916:AU14_RS05345
uniprot id: W5YGF3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1420916:AU14 RS13540
gene id: 1420916:AU14_RS13540
uniprot id: W5YJ99
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1420916:AU14 RS18160
gene id: 1420916:AU14_RS18160
uniprot id: W5YTU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1420916:AU14 RS06365
gene id: 1420916:AU14_RS06365
uniprot id: W5YHU1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS18070
gene id: 1420916:AU14_RS18070
uniprot id: W5YLT6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1420916:AU14 RS14205
gene id: 1420916:AU14_RS14205
uniprot id: W5YJZ1
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS06615
gene id: 1420916:AU14_RS06615
uniprot id: W5YHF1
names: Similarity
messages: Belongs to the MotB family.

1420916:AU14 RS08740
gene id: 1420916:AU14_RS08740
uniprot id: W5YHL5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1420916:AU14 RS06580
gene id: 1420916:AU14_RS06580
uniprot id: W5YH80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1420916:AU14 RS17150
gene id: 1420916:AU14_RS17150
uniprot id: W5YL00
names: Similarity
messages: Belongs to the UPF0246 family.

1420916:AU14 RS07975
gene id: 1420916:AU14_RS07975
uniprot id: W5YQ53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1420916:AU14 RS08900
gene id: 1420916:AU14_RS08900
uniprot id: W5YI17
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1420916:AU14 RS13270
gene id: 1420916:AU14_RS13270
uniprot id: W5YS11
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1420916:AU14 RS05770
gene id: 1420916:AU14_RS05770
uniprot id: W5YH18
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1420916:AU14 RS01370
gene id: 1420916:AU14_RS01370
uniprot id: W5YFN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1420916:AU14 RS03860
gene id: 1420916:AU14_RS03860
uniprot id: W5YNP5
names: Similarity
messages: Belongs to the MQO family.

1420916:AU14 RS15540
gene id: 1420916:AU14_RS15540
uniprot id: W5YSV7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1420916:AU14 RS08100
gene id: 1420916:AU14_RS08100
uniprot id: W5YHC6
names: Similarity
messages: Belongs to the TrpC family.

1420916:AU14 RS18010
gene id: 1420916:AU14_RS18010
uniprot id: W5YTP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1420916:AU14 RS08805
gene id: 1420916:AU14_RS08805
uniprot id: W5YI06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1420916:AU14 RS03030
gene id: 1420916:AU14_RS03030
uniprot id: W5YGJ8
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1420916:AU14 RS02760
gene id: 1420916:AU14_RS02760
uniprot id: W5YG52
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1420916:AU14 RS10545
gene id: 1420916:AU14_RS10545
uniprot id: W5YIQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1420916:AU14 RS10135
gene id: 1420916:AU14_RS10135
uniprot id: W5YIL1
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS08445
gene id: 1420916:AU14_RS08445
uniprot id: W5YII1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1420916:AU14 RS18115
gene id: 1420916:AU14_RS18115
uniprot id: W5YLD3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS09095
gene id: 1420916:AU14_RS09095
uniprot id: W5YQK2
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1420916:AU14 RS07820
gene id: 1420916:AU14_RS07820
uniprot id: W5YHL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1420916:AU14 RS10055
gene id: 1420916:AU14_RS10055
uniprot id: W5YJ94
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1420916:AU14 RS05515
gene id: 1420916:AU14_RS05515
uniprot id: W5YP89
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1420916:AU14 RS15200
gene id: 1420916:AU14_RS15200
uniprot id: W5YSR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1420916:AU14 RS10215
gene id: 1420916:AU14_RS10215
uniprot id: W5YIL3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1420916:AU14 RS11615
gene id: 1420916:AU14_RS11615
uniprot id: W5YJ09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1420916:AU14 RS05850
gene id: 1420916:AU14_RS05850
uniprot id: W5YGM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS03410
gene id: 1420916:AU14_RS03410
uniprot id: W5YFP9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1420916:AU14 RS14310
gene id: 1420916:AU14_RS14310
uniprot id: W5YJZ8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1420916:AU14 RS11790
gene id: 1420916:AU14_RS11790
uniprot id: W5YIM7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS03655
gene id: 1420916:AU14_RS03655
uniprot id: W5YGQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1420916:AU14 RS16670
gene id: 1420916:AU14_RS16670
uniprot id: W5YKT9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1420916:AU14 RS18095
gene id: 1420916:AU14_RS18095
uniprot id: W5YTS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1420916:AU14 RS12965
gene id: 1420916:AU14_RS12965
uniprot id: W5YK24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1420916:AU14 RS16160
gene id: 1420916:AU14_RS16160
uniprot id: W5YT22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1420916:AU14 RS02945
gene id: 1420916:AU14_RS02945
uniprot id: W5YFL7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1420916:AU14 RS09270
gene id: 1420916:AU14_RS09270
uniprot id: W5YI87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1420916:AU14 RS12690
gene id: 1420916:AU14_RS12690
uniprot id: W5YJC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1420916:AU14 RS04645
gene id: 1420916:AU14_RS04645
uniprot id: W5YG50
names: Similarity
messages: Belongs to the UPF0229 family.

1420916:AU14 RS01995
gene id: 1420916:AU14_RS01995
uniprot id: W5YFY4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS09815
gene id: 1420916:AU14_RS09815
uniprot id: W5YJ55
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1420916:AU14 RS16585
gene id: 1420916:AU14_RS16585
uniprot id: W5YKV0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS15100
gene id: 1420916:AU14_RS15100
uniprot id: W5YJV4
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

1420916:AU14 RS09120
gene id: 1420916:AU14_RS09120
uniprot id: W5YI66
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1420916:AU14 RS04900
gene id: 1420916:AU14_RS04900
uniprot id: W5YP15
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1420916:AU14 RS05955
gene id: 1420916:AU14_RS05955
uniprot id: W5YH24
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1420916:AU14 RS16465
gene id: 1420916:AU14_RS16465
uniprot id: W5YL93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1420916:AU14 RS02075
gene id: 1420916:AU14_RS02075
uniprot id: W5YN59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS09600
gene id: 1420916:AU14_RS09600
uniprot id: W5YIZ9
names: Subcellular Location Annotation
messages: Cytoplasm

1420916:AU14 RS04215
gene id: 1420916:AU14_RS04215
uniprot id: W5YGJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

1420916:AU14 RS17255
gene id: 1420916:AU14_RS17255
uniprot id: W5YLF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1420916:AU14 RS16575
gene id: 1420916:AU14_RS16575
uniprot id: W5YT74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1420916:AU14 RS13410
gene id: 1420916:AU14_RS13410
uniprot id: W5YS30
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1420916:AU14 RS12750
gene id: 1420916:AU14_RS12750
uniprot id: W5YJD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1420916:AU14 RS17735
gene id: 1420916:AU14_RS17735
uniprot id: W5YL60
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS09650
gene id: 1420916:AU14_RS09650
uniprot id: W5YID9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS12185
gene id: 1420916:AU14_RS12185
uniprot id: W5YJ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1420916:AU14 RS01430
gene id: 1420916:AU14_RS01430
uniprot id: W5YFD4
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1420916:AU14 RS10670
gene id: 1420916:AU14_RS10670
uniprot id: W5YIQ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS07345
gene id: 1420916:AU14_RS07345
uniprot id: W5YHL7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1420916:AU14 RS10590
gene id: 1420916:AU14_RS10590
uniprot id: W5YJE6
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1420916:AU14 RS08265
gene id: 1420916:AU14_RS08265
uniprot id: W5YHS7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1420916:AU14 RS00905
gene id: 1420916:AU14_RS00905
uniprot id: W5YFJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1420916:AU14 RS10655
gene id: 1420916:AU14_RS10655
uniprot id: W5YIR6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1420916:AU14 RS12800
gene id: 1420916:AU14_RS12800
uniprot id: W5YRT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1420916:AU14 RS04580
gene id: 1420916:AU14_RS04580
uniprot id: W5YG40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1420916:AU14 RS00660
gene id: 1420916:AU14_RS00660
uniprot id: W5YFG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1420916:AU14 RS16000
gene id: 1420916:AU14_RS16000
uniprot id: W5YK41
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1420916:AU14 RS01475
gene id: 1420916:AU14_RS01475
uniprot id: W5YFP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1420916:AU14 RS04745
gene id: 1420916:AU14_RS04745
uniprot id: W5YGJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1420916:AU14 RS14165
gene id: 1420916:AU14_RS14165
uniprot id: W5YJY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1420916:AU14 RS16235
gene id: 1420916:AU14_RS16235
uniprot id: W5YKP3
names: Similarity
messages: Belongs to the Skp family.

1420916:AU14 RS06955
gene id: 1420916:AU14_RS06955
uniprot id: W5YPT5
names: Similarity
messages: Belongs to the YkuD family.

1420916:AU14 RS14590
gene id: 1420916:AU14_RS14590
uniprot id: W5YK44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1420916:AU14 RS13865
gene id: 1420916:AU14_RS13865
uniprot id: W5YJU3
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1420916:AU14 RS08230
gene id: 1420916:AU14_RS08230
uniprot id: W5YHX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

1420916:AU14 RS07640
gene id: 1420916:AU14_RS07640
uniprot id: W5YI89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1420916:AU14 RS16545
gene id: 1420916:AU14_RS16545
uniprot id: W5YKB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1420916:AU14 RS06220
gene id: 1420916:AU14_RS06220
uniprot id: W5YHB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS16165
gene id: 1420916:AU14_RS16165
uniprot id: W5YL59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS17290
gene id: 1420916:AU14_RS17290
uniprot id: W5YTE2
names: Similarity
messages: Belongs to the histone deacetylase family.

1420916:AU14 RS05420
gene id: 1420916:AU14_RS05420
uniprot id: W5YP80
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1420916:AU14 RS13525
gene id: 1420916:AU14_RS13525
uniprot id: W5YJQ0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1420916:AU14 RS01570
gene id: 1420916:AU14_RS01570
uniprot id: W5YFQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1420916:AU14 RS07650
gene id: 1420916:AU14_RS07650
uniprot id: W5YHJ6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1420916:AU14 RS00870
gene id: 1420916:AU14_RS00870
uniprot id: W5YEX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1420916:AU14 RS04075
gene id: 1420916:AU14_RS04075
uniprot id: W5YGI2
names: Similarity
messages: Belongs to the leucine-binding protein family.

1420916:AU14 RS08950
gene id: 1420916:AU14_RS08950
uniprot id: W5YIQ5
names: Similarity
messages: Belongs to the UPF0047 family.

1420916:AU14 RS07925
gene id: 1420916:AU14_RS07925
uniprot id: W5YHT4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1420916:AU14 RS10780
gene id: 1420916:AU14_RS10780
uniprot id: W5YID5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1420916:AU14 RS11295
gene id: 1420916:AU14_RS11295
uniprot id: W5YIY4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1420916:AU14 RS07370
gene id: 1420916:AU14_RS07370
uniprot id: W5YHM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1420916:AU14 RS10565
gene id: 1420916:AU14_RS10565
uniprot id: W5YJE1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1420916:AU14 RS17170
gene id: 1420916:AU14_RS17170
uniprot id: W5YLE8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1420916:AU14 RS03005
gene id: 1420916:AU14_RS03005
uniprot id: W5YFM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1420916:AU14 RS11230
gene id: 1420916:AU14_RS11230
uniprot id: W5YIX3
names: Similarity
messages: Belongs to the P(II) protein family.

1420916:AU14 RS11575
gene id: 1420916:AU14_RS11575
uniprot id: W5YJ05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1420916:AU14 RS08650
gene id: 1420916:AU14_RS08650
uniprot id: W5YIK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1420916:AU14 RS03395
gene id: 1420916:AU14_RS03395
uniprot id: W5YG29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1420916:AU14 RS03595
gene id: 1420916:AU14_RS03595
uniprot id: W5YFS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS16170
gene id: 1420916:AU14_RS16170
uniprot id: W5YKN1
names: Similarity
messages: Belongs to the ArsC family.

1420916:AU14 RS15625
gene id: 1420916:AU14_RS15625
uniprot id: W5YKG7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1420916:AU14 RS14420
gene id: 1420916:AU14_RS14420
uniprot id: W5YK05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1420916:AU14 RS14895
gene id: 1420916:AU14_RS14895
uniprot id: W5YK55
names: Similarity
messages: Belongs to the MipA/OmpV family.

1420916:AU14 RS07170
gene id: 1420916:AU14_RS07170
uniprot id: W5YHK4
names: Subunit
messages: Homodimer.

1420916:AU14 RS01420
gene id: 1420916:AU14_RS01420
uniprot id: W5YFW7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS06180
gene id: 1420916:AU14_RS06180
uniprot id: W5YPL0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1420916:AU14 RS17215
gene id: 1420916:AU14_RS17215
uniprot id: W5YKH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1420916:AU14 RS12170
gene id: 1420916:AU14_RS12170
uniprot id: W5YJU0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1420916:AU14 RS10085
gene id: 1420916:AU14_RS10085
uniprot id: W5YR10
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1420916:AU14 RS17725
gene id: 1420916:AU14_RS17725
uniprot id: W5YLM0
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS15730
gene id: 1420916:AU14_RS15730
uniprot id: W5YKH8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1420916:AU14 RS10795
gene id: 1420916:AU14_RS10795
uniprot id: W5YR75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1420916:AU14 RS12745
gene id: 1420916:AU14_RS12745
uniprot id: W5YJY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1420916:AU14 RS04920
gene id: 1420916:AU14_RS04920
uniprot id: W5YGS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1420916:AU14 RS05120
gene id: 1420916:AU14_RS05120
uniprot id: W5YGB9
names: Similarity
messages: Belongs to the GST superfamily.

1420916:AU14 RS10675
gene id: 1420916:AU14_RS10675
uniprot id: W5YIC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1420916:AU14 RS18195
gene id: 1420916:AU14_RS18195
uniprot id: W5YTV6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1420916:AU14 RS14490
gene id: 1420916:AU14_RS14490
uniprot id: W5YK13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

1420916:AU14 RS11845
gene id: 1420916:AU14_RS11845
uniprot id: W5YRI7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1420916:AU14 RS04440
gene id: 1420916:AU14_RS04440
uniprot id: W5YGG2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1420916:AU14 RS00755
gene id: 1420916:AU14_RS00755
uniprot id: W5YFH9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1420916:AU14 RS14100
gene id: 1420916:AU14_RS14100
uniprot id: W5YJX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS06075
gene id: 1420916:AU14_RS06075
uniprot id: W5YH34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1420916:AU14 RS05595
gene id: 1420916:AU14_RS05595
uniprot id: W5YH04
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1420916:AU14 RS04990
gene id: 1420916:AU14_RS04990
uniprot id: W5YGT1
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS18100
gene id: 1420916:AU14_RS18100
uniprot id: W5YLW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1420916:AU14 RS06555
gene id: 1420916:AU14_RS06555
uniprot id: W5YPP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1420916:AU14 RS11865
gene id: 1420916:AU14_RS11865
uniprot id: W5YJ41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1420916:AU14 RS02135
gene id: 1420916:AU14_RS02135
uniprot id: W5YFP6
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1420916:AU14 RS14520
gene id: 1420916:AU14_RS14520
uniprot id: W5YK15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1420916:AU14 RS01695
gene id: 1420916:AU14_RS01695
uniprot id: W5YFS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1420916:AU14 RS14790
gene id: 1420916:AU14_RS14790
uniprot id: W5YJS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1420916:AU14 RS12390
gene id: 1420916:AU14_RS12390
uniprot id: W5YJ91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1420916:AU14 RS02380
gene id: 1420916:AU14_RS02380
uniprot id: W5YGC7
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS17975
gene id: 1420916:AU14_RS17975
uniprot id: W5YTN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1420916:AU14 RS13010
gene id: 1420916:AU14_RS13010
uniprot id: W5YRW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1420916:AU14 RS14885
gene id: 1420916:AU14_RS14885
uniprot id: W5YK80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1420916:AU14 RS15320
gene id: 1420916:AU14_RS15320
uniprot id: W5YKD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1420916:AU14 RS10130
gene id: 1420916:AU14_RS10130
uniprot id: W5YJA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1420916:AU14 RS01835
gene id: 1420916:AU14_RS01835
uniprot id: W5YFL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS03835
gene id: 1420916:AU14_RS03835
uniprot id: W5YGS0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1420916:AU14 RS06815
gene id: 1420916:AU14_RS06815
uniprot id: W5YPS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1420916:AU14 RS16240
gene id: 1420916:AU14_RS16240
uniprot id: W5YKL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1420916:AU14 RS15885
gene id: 1420916:AU14_RS15885
uniprot id: W5YK27
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS04250
gene id: 1420916:AU14_RS04250
uniprot id: W5YGK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1420916:AU14 RS02935
gene id: 1420916:AU14_RS02935
uniprot id: W5YG68
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1420916:AU14 RS15310
gene id: 1420916:AU14_RS15310
uniprot id: W5YST4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1420916:AU14 RS12280
gene id: 1420916:AU14_RS12280
uniprot id: W5YRM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1420916:AU14 RS17165
gene id: 1420916:AU14_RS17165
uniprot id: W5YTC6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.

1420916:AU14 RS11775
gene id: 1420916:AU14_RS11775
uniprot id: W5YJP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1420916:AU14 RS04205
gene id: 1420916:AU14_RS04205
uniprot id: W5YGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS16610
gene id: 1420916:AU14_RS16610
uniprot id: W5YKC1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS10580
gene id: 1420916:AU14_RS10580
uniprot id: W5YIB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1420916:AU14 RS08165
gene id: 1420916:AU14_RS08165
uniprot id: W5YHR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1420916:AU14 RS04380
gene id: 1420916:AU14_RS04380
uniprot id: W5YNV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1420916:AU14 RS04830
gene id: 1420916:AU14_RS04830
uniprot id: W5YH42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS03230
gene id: 1420916:AU14_RS03230
uniprot id: W5YG15
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1420916:AU14 RS16325
gene id: 1420916:AU14_RS16325
uniprot id: W5YT43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1420916:AU14 RS11645
gene id: 1420916:AU14_RS11645
uniprot id: W5YJN2
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1420916:AU14 RS14115
gene id: 1420916:AU14_RS14115
uniprot id: W5YKN2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1420916:AU14 RS11780
gene id: 1420916:AU14_RS11780
uniprot id: W5YJ36
names: Similarity
messages: Belongs to the PhoH family.

1420916:AU14 RS12790
gene id: 1420916:AU14_RS12790
uniprot id: W5YJE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1420916:AU14 RS14455
gene id: 1420916:AU14_RS14455
uniprot id: W5YK09
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS15830
gene id: 1420916:AU14_RS15830
uniprot id: W5YKJ3
names: Similarity
messages: Belongs to the peptidase S16 family.

1420916:AU14 RS08535
gene id: 1420916:AU14_RS08535
uniprot id: W5YIJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1420916:AU14 RS06825
gene id: 1420916:AU14_RS06825
uniprot id: W5YHZ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1420916:AU14 RS15155
gene id: 1420916:AU14_RS15155
uniprot id: W5YJV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS04230
gene id: 1420916:AU14_RS04230
uniprot id: W5YFZ6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1420916:AU14 RS10850
gene id: 1420916:AU14_RS10850
uniprot id: W5YJG7
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS13040
gene id: 1420916:AU14_RS13040
uniprot id: W5YK40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1420916:AU14 RS12460
gene id: 1420916:AU14_RS12460
uniprot id: W5YJA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1420916:AU14 RS04020
gene id: 1420916:AU14_RS04020
uniprot id: W5YGA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1420916:AU14 RS18015
gene id: 1420916:AU14_RS18015
uniprot id: W5YLS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1420916:AU14 RS08810
gene id: 1420916:AU14_RS08810
uniprot id: W5YHM3
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS02930
gene id: 1420916:AU14_RS02930
uniprot id: W5YGI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1420916:AU14 RS07480
gene id: 1420916:AU14_RS07480
uniprot id: W5YI70
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS11015
gene id: 1420916:AU14_RS11015
uniprot id: W5YJH7
names: Similarity
messages: Belongs to the GppA/Ppx family.

1420916:AU14 RS11930
gene id: 1420916:AU14_RS11930
uniprot id: W5YIP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

1420916:AU14 RS00395
gene id: 1420916:AU14_RS00395
uniprot id: W5YER0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS07935
gene id: 1420916:AU14_RS07935
uniprot id: W5YHA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1420916:AU14 RS08450
gene id: 1420916:AU14_RS08450
uniprot id: W5YI02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1420916:AU14 RS09005
gene id: 1420916:AU14_RS09005
uniprot id: W5YI30
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1420916:AU14 RS17330
gene id: 1420916:AU14_RS17330
uniprot id: W5YTE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1420916:AU14 RS08570
gene id: 1420916:AU14_RS08570
uniprot id: W5YIJ4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1420916:AU14 RS08905
gene id: 1420916:AU14_RS08905
uniprot id: W5YHN8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1420916:AU14 RS05520
gene id: 1420916:AU14_RS05520
uniprot id: W5YHE2
names: Similarity
messages: Belongs to the Gfa family.

1420916:AU14 RS08700
gene id: 1420916:AU14_RS08700
uniprot id: W5YQE7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1420916:AU14 RS04335
gene id: 1420916:AU14_RS04335
uniprot id: W5YNU7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1420916:AU14 RS15510
gene id: 1420916:AU14_RS15510
uniprot id: W5YSV2
names: Similarity
messages: Belongs to the VgrG protein family.

1420916:AU14 RS11785
gene id: 1420916:AU14_RS11785
uniprot id: W5YJ28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1420916:AU14 RS11735
gene id: 1420916:AU14_RS11735
uniprot id: W5YJP3
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

1420916:AU14 RS05795
gene id: 1420916:AU14_RS05795
uniprot id: W5YH21
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1420916:AU14 RS05415
gene id: 1420916:AU14_RS05415
uniprot id: W5YGG5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1420916:AU14 RS12760
gene id: 1420916:AU14_RS12760
uniprot id: W5YIZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1420916:AU14 RS00810
gene id: 1420916:AU14_RS00810
uniprot id: W5YEX1
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1420916:AU14 RS07960
gene id: 1420916:AU14_RS07960
uniprot id: W5YHN7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS18430
gene id: 1420916:AU14_RS18430
uniprot id: W5YLE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1420916:AU14 RS00710
gene id: 1420916:AU14_RS00710
uniprot id: W5YFN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1420916:AU14 RS03415
gene id: 1420916:AU14_RS03415
uniprot id: W5YNJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS00450
gene id: 1420916:AU14_RS00450
uniprot id: W5YF34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1420916:AU14 RS08185
gene id: 1420916:AU14_RS08185
uniprot id: W5YHW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1420916:AU14 RS06945
gene id: 1420916:AU14_RS06945
uniprot id: W5YHB5
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS02960
gene id: 1420916:AU14_RS02960
uniprot id: W5YG73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1420916:AU14 RS02560
gene id: 1420916:AU14_RS02560
uniprot id: W5YFI3
names: Similarity
messages: Belongs to the acylphosphatase family.

1420916:AU14 RS12730
gene id: 1420916:AU14_RS12730
uniprot id: W5YIZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1420916:AU14 RS02910
gene id: 1420916:AU14_RS02910
uniprot id: W5YFL5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1420916:AU14 RS05820
gene id: 1420916:AU14_RS05820
uniprot id: W5YGL7
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS01380
gene id: 1420916:AU14_RS01380
uniprot id: W5YFD0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1420916:AU14 RS06290
gene id: 1420916:AU14_RS06290
uniprot id: W5YLX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S45 family.
messages: Periplasm

1420916:AU14 RS04515
gene id: 1420916:AU14_RS04515
uniprot id: W5YNW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1420916:AU14 RS04715
gene id: 1420916:AU14_RS04715
uniprot id: W5YH35
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1420916:AU14 RS16290
gene id: 1420916:AU14_RS16290
uniprot id: W5YK77
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1420916:AU14 RS16505
gene id: 1420916:AU14_RS16505
uniprot id: W5YKA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1420916:AU14 RS02890
gene id: 1420916:AU14_RS02890
uniprot id: W5YNE0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1420916:AU14 RS08340
gene id: 1420916:AU14_RS08340
uniprot id: W5YQ96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS11450
gene id: 1420916:AU14_RS11450
uniprot id: W5YII8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1420916:AU14 RS08775
gene id: 1420916:AU14_RS08775
uniprot id: W5YHM0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1420916:AU14 RS11370
gene id: 1420916:AU14_RS11370
uniprot id: W5YJK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1420916:AU14 RS01565
gene id: 1420916:AU14_RS01565
uniprot id: W5YFZ3
names: Similarity
messages: Belongs to the DsrF/TusC family.

1420916:AU14 RS05175
gene id: 1420916:AU14_RS05175
uniprot id: W5YGV4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1420916:AU14 RS13745
gene id: 1420916:AU14_RS13745
uniprot id: W5YS75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1420916:AU14 RS04670
gene id: 1420916:AU14_RS04670
uniprot id: W5YGJ1
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS06190
gene id: 1420916:AU14_RS06190
uniprot id: W5YHR8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1420916:AU14 RS11840
gene id: 1420916:AU14_RS11840
uniprot id: W5YIN1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1420916:AU14 RS12380
gene id: 1420916:AU14_RS12380
uniprot id: W5YRN2
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1420916:AU14 RS05760
gene id: 1420916:AU14_RS05760
uniprot id: W5YHH0
names: Subcellular Location Annotation
messages: Cytoplasm

1420916:AU14 RS12970
gene id: 1420916:AU14_RS12970
uniprot id: W5YJG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1420916:AU14 RS03935
gene id: 1420916:AU14_RS03935
uniprot id: W5YGG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1420916:AU14 RS00300
gene id: 1420916:AU14_RS00300
uniprot id: W5YFI2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1420916:AU14 RS17940
gene id: 1420916:AU14_RS17940
uniprot id: W5YTM9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1420916:AU14 RS03640
gene id: 1420916:AU14_RS03640
uniprot id: W5YFS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1420916:AU14 RS06700
gene id: 1420916:AU14_RS06700
uniprot id: W5YPR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1420916:AU14 RS16595
gene id: 1420916:AU14_RS16595
uniprot id: W5YKS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1420916:AU14 RS03435
gene id: 1420916:AU14_RS03435
uniprot id: W5YGA9
names: Similarity
messages: Belongs to the UPF0045 family.

1420916:AU14 RS06550
gene id: 1420916:AU14_RS06550
uniprot id: W5YGX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1420916:AU14 RS08455
gene id: 1420916:AU14_RS08455
uniprot id: W5YHV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1420916:AU14 RS08440
gene id: 1420916:AU14_RS08440
uniprot id: W5YQB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS06415
gene id: 1420916:AU14_RS06415
uniprot id: W5YPN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1420916:AU14 RS12680
gene id: 1420916:AU14_RS12680
uniprot id: W5YJY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1420916:AU14 RS06135
gene id: 1420916:AU14_RS06135
uniprot id: W5YH40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1420916:AU14 RS13560
gene id: 1420916:AU14_RS13560
uniprot id: W5YJP9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1420916:AU14 RS16260
gene id: 1420916:AU14_RS16260
uniprot id: W5YL70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1420916:AU14 RS11520
gene id: 1420916:AU14_RS11520
uniprot id: W5YJ06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1420916:AU14 RS11425
gene id: 1420916:AU14_RS11425
uniprot id: W5YIZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1420916:AU14 RS05630
gene id: 1420916:AU14_RS05630
uniprot id: W5YHF3
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1420916:AU14 RS02750
gene id: 1420916:AU14_RS02750
uniprot id: W5YGG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1420916:AU14 RS08280
gene id: 1420916:AU14_RS08280
uniprot id: W5YIG6
names: Similarity
messages: Belongs to the Dps family.

1420916:AU14 RS15360
gene id: 1420916:AU14_RS15360
uniprot id: W5YKD8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1420916:AU14 RS00460
gene id: 1420916:AU14_RS00460
uniprot id: W5YES2
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1420916:AU14 RS00745
gene id: 1420916:AU14_RS00745
uniprot id: W5YMM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1420916:AU14 RS01980
gene id: 1420916:AU14_RS01980
uniprot id: W5YL68
names: Similarity
messages: Belongs to the universal stress protein A family.

1420916:AU14 RS00465
gene id: 1420916:AU14_RS00465
uniprot id: W5YMI6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1420916:AU14 RS14580
gene id: 1420916:AU14_RS14580
uniprot id: W5YKS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1420916:AU14 RS02965
gene id: 1420916:AU14_RS02965
uniprot id: W5YFZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1420916:AU14 RS00705
gene id: 1420916:AU14_RS00705
uniprot id: W5YML9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1420916:AU14 RS03600
gene id: 1420916:AU14_RS03600
uniprot id: W5YNL5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1420916:AU14 RS07290
gene id: 1420916:AU14_RS07290
uniprot id: W5YPX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1420916:AU14 RS08500
gene id: 1420916:AU14_RS08500
uniprot id: W5YHW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1420916:AU14 RS10395
gene id: 1420916:AU14_RS10395
uniprot id: W5YR38
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS07365
gene id: 1420916:AU14_RS07365
uniprot id: W5YI59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1420916:AU14 RS03840
gene id: 1420916:AU14_RS03840
uniprot id: W5YGF5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1420916:AU14 RS06595
gene id: 1420916:AU14_RS06595
uniprot id: W5YGX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1420916:AU14 RS17495
gene id: 1420916:AU14_RS17495
uniprot id: W5YTH0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1420916:AU14 RS02070
gene id: 1420916:AU14_RS02070
uniprot id: W5YFD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS18210
gene id: 1420916:AU14_RS18210
uniprot id: W5YLE1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1420916:AU14 RS09245
gene id: 1420916:AU14_RS09245
uniprot id: W5YI67
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1420916:AU14 RS16370
gene id: 1420916:AU14_RS16370
uniprot id: W5YKN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1420916:AU14 RS10410
gene id: 1420916:AU14_RS10410
uniprot id: W5YIM9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

1420916:AU14 RS10610
gene id: 1420916:AU14_RS10610
uniprot id: W5YIQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1420916:AU14 RS00845
gene id: 1420916:AU14_RS00845
uniprot id: W5YFP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1420916:AU14 RS12950
gene id: 1420916:AU14_RS12950
uniprot id: W5YJ20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1420916:AU14 RS08395
gene id: 1420916:AU14_RS08395
uniprot id: W5YHZ2
names: Similarity
messages: Belongs to the UPF0102 family.

1420916:AU14 RS02810
gene id: 1420916:AU14_RS02810
uniprot id: W5YG54
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1420916:AU14 RS18060
gene id: 1420916:AU14_RS18060
uniprot id: W5YTQ3
names: Similarity
messages: Belongs to the peptidase M24B family.

1420916:AU14 RS14495
gene id: 1420916:AU14_RS14495
uniprot id: W5YJP5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1420916:AU14 RS13655
gene id: 1420916:AU14_RS13655
uniprot id: W5YJR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1420916:AU14 RS12070
gene id: 1420916:AU14_RS12070
uniprot id: W5YRL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1420916:AU14 RS07700
gene id: 1420916:AU14_RS07700
uniprot id: W5YI97
names: Subcellular Location Annotation
messages: Cytoplasm

1420916:AU14 RS14710
gene id: 1420916:AU14_RS14710
uniprot id: W5YKT4
names: Subcellular Location Annotation
messages: Membrane

1420916:AU14 RS03660
gene id: 1420916:AU14_RS03660
uniprot id: W5YGD3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1420916:AU14 RS03910
gene id: 1420916:AU14_RS03910
uniprot id: W5YG94
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1420916:AU14 RS08875
gene id: 1420916:AU14_RS08875
uniprot id: W5YIP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1420916:AU14 RS17130
gene id: 1420916:AU14_RS17130
uniprot id: W5YKG5
names: Similarity
messages: Belongs to the histone deacetylase family.

1420916:AU14 RS02880
gene id: 1420916:AU14_RS02880
uniprot id: W5YFX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1420916:AU14 RS09675
gene id: 1420916:AU14_RS09675
uniprot id: W5YIE5
names: Similarity
messages: Belongs to the peptidase C56 family.

1420916:AU14 RS13755
gene id: 1420916:AU14_RS13755
uniprot id: W5YKF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1420916:AU14 RS12985
gene id: 1420916:AU14_RS12985
uniprot id: W5YRW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1420916:AU14 RS11260
gene id: 1420916:AU14_RS11260
uniprot id: W5YJJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1420916:AU14 RS08065
gene id: 1420916:AU14_RS08065
uniprot id: W5YHC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1420916:AU14 RS02990
gene id: 1420916:AU14_RS02990
uniprot id: W5YGJ3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1420916:AU14 RS08430
gene id: 1420916:AU14_RS08430
uniprot id: W5YHH9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1420916:AU14 RS15300
gene id: 1420916:AU14_RS15300
uniprot id: W5YKA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1420916:AU14 RS06435
gene id: 1420916:AU14_RS06435
uniprot id: W5YH69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1420916:AU14 RS13120
gene id: 1420916:AU14_RS13120
uniprot id: W5YRY9
names: Similarity
messages: Belongs to the GSP E family.

1420916:AU14 RS01730
gene id: 1420916:AU14_RS01730
uniprot id: W5YFI1
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1420916:AU14 RS04895
gene id: 1420916:AU14_RS04895
uniprot id: W5YG83
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1420916:AU14 RS08090
gene id: 1420916:AU14_RS08090
uniprot id: W5YHQ2
names: Similarity
messages: Belongs to the GST superfamily.

1420916:AU14 RS11745
gene id: 1420916:AU14_RS11745
uniprot id: W5YJ23
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

1420916:AU14 RS06710
gene id: 1420916:AU14_RS06710
uniprot id: W5YHY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1420916:AU14 RS14010
gene id: 1420916:AU14_RS14010
uniprot id: W5YSF2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1420916:AU14 RS05965
gene id: 1420916:AU14_RS05965
uniprot id: W5YGQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1420916:AU14 RS08690
gene id: 1420916:AU14_RS08690
uniprot id: W5YHZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1420916:AU14 RS14160
gene id: 1420916:AU14_RS14160
uniprot id: W5YK04
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1420916:AU14 RS02305
gene id: 1420916:AU14_RS02305
uniprot id: W5YGB8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1420916:AU14 RS03730
gene id: 1420916:AU14_RS03730
uniprot id: W5YNN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1420916:AU14 RS12490
gene id: 1420916:AU14_RS12490
uniprot id: W5YJA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1420916:AU14 RS08155
gene id: 1420916:AU14_RS08155
uniprot id: W5YHW5
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1420916:AU14 RS17120
gene id: 1420916:AU14_RS17120
uniprot id: W5YKX2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1420916:AU14 RS02885
gene id: 1420916:AU14_RS02885
uniprot id: W5YFL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1420916:AU14 RS00735
gene id: 1420916:AU14_RS00735
uniprot id: W5YF70
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.