1408189:CLAC RS10620
gene id: 1408189:CLAC_RS10620
uniprot id: A0A0K2H2Y8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1408189:CLAC RS10870
gene id: 1408189:CLAC_RS10870
uniprot id: A0A0K2H337
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1408189:CLAC RS02205
gene id: 1408189:CLAC_RS02205
uniprot id: A0A0K2GYJ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1408189:CLAC RS02420
gene id: 1408189:CLAC_RS02420
uniprot id: A0A0K2GYC4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1408189:CLAC RS00095
gene id: 1408189:CLAC_RS00095
uniprot id: A0A0K2GX81
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS05655
gene id: 1408189:CLAC_RS05655
uniprot id: A0A0K2GZU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1408189:CLAC RS03035
gene id: 1408189:CLAC_RS03035
uniprot id: A0A0K2GYM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1408189:CLAC RS10730
gene id: 1408189:CLAC_RS10730
uniprot id: A0A0K2H236
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS02190
gene id: 1408189:CLAC_RS02190
uniprot id: A0A0K2GY83
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1408189:CLAC RS08260
gene id: 1408189:CLAC_RS08260
uniprot id: A0A0K2H4F0
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS06965
gene id: 1408189:CLAC_RS06965
uniprot id: A0A0K2H1C2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1408189:CLAC RS09320
gene id: 1408189:CLAC_RS09320
uniprot id: A0A0K2H2G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1408189:CLAC RS06930
gene id: 1408189:CLAC_RS06930
uniprot id: A0A0K2H0F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1408189:CLAC RS06960
gene id: 1408189:CLAC_RS06960
uniprot id: A0A0K2H0G2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1408189:CLAC RS09725
gene id: 1408189:CLAC_RS09725
uniprot id: A0A0K2H2J8
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1408189:CLAC RS10725
gene id: 1408189:CLAC_RS10725
uniprot id: A0A0K2H312
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS03465
gene id: 1408189:CLAC_RS03465
uniprot id: A0A0K2GYS3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS01155
gene id: 1408189:CLAC_RS01155
uniprot id: A0A0K2GY09
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS00335
gene id: 1408189:CLAC_RS00335
uniprot id: A0A0K2GXC0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1408189:CLAC RS06375
gene id: 1408189:CLAC_RS06375
uniprot id: A0A0K2H066
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1408189:CLAC RS11350
gene id: 1408189:CLAC_RS11350
uniprot id: A0A0K2H2E7
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS05795
gene id: 1408189:CLAC_RS05795
uniprot id: A0A0K2GZW3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1408189:CLAC RS04920
gene id: 1408189:CLAC_RS04920
uniprot id: A0A0K2GZG2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1408189:CLAC RS10360
gene id: 1408189:CLAC_RS10360
uniprot id: A0A0K2H1X4
names: Similarity
messages: Belongs to the GARS family.

1408189:CLAC RS10750
gene id: 1408189:CLAC_RS10750
uniprot id: A0A0K2H317
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1408189:CLAC RS06700
gene id: 1408189:CLAC_RS06700
uniprot id: A0A0K2H176
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1408189:CLAC RS05255
gene id: 1408189:CLAC_RS05255
uniprot id: A0A0K2GZL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1408189:CLAC RS03920
gene id: 1408189:CLAC_RS03920
uniprot id: A0A0K2GYZ6
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS02130
gene id: 1408189:CLAC_RS02130
uniprot id: A0A0K2H2Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

1408189:CLAC RS07450
gene id: 1408189:CLAC_RS07450
uniprot id: A0A0K2H1I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1408189:CLAC RS03085
gene id: 1408189:CLAC_RS03085
uniprot id: A0A0K2GYN0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1408189:CLAC RS08050
gene id: 1408189:CLAC_RS08050
uniprot id: A0A0K2H0Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS05825
gene id: 1408189:CLAC_RS05825
uniprot id: A0A0K2H0V0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1408189:CLAC RS06925
gene id: 1408189:CLAC_RS06925
uniprot id: A0A0K2H0G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1408189:CLAC RS10735
gene id: 1408189:CLAC_RS10735
uniprot id: A0A0K2H2D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS08375
gene id: 1408189:CLAC_RS08375
uniprot id: A0A0K2H1F3
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS07435
gene id: 1408189:CLAC_RS07435
uniprot id: A0A0K2H0W9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS07875
gene id: 1408189:CLAC_RS07875
uniprot id: A0A0K2H0W1
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1408189:CLAC RS09345
gene id: 1408189:CLAC_RS09345
uniprot id: A0A0K2H2H1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1408189:CLAC RS04105
gene id: 1408189:CLAC_RS04105
uniprot id: A0A0K2GZ21
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1408189:CLAC RS09285
gene id: 1408189:CLAC_RS09285
uniprot id: A0A0K2H1I7
names: Similarity
messages: Belongs to the peptidase S1C family.

1408189:CLAC RS05865
gene id: 1408189:CLAC_RS05865
uniprot id: A0A0K2GZY3
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1408189:CLAC RS05130
gene id: 1408189:CLAC_RS05130
uniprot id: A0A0K2H0H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1408189:CLAC RS08955
gene id: 1408189:CLAC_RS08955
uniprot id: A0A0K2H1D3
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS05995
gene id: 1408189:CLAC_RS05995
uniprot id: A0A0K2GZZ8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1408189:CLAC RS07855
gene id: 1408189:CLAC_RS07855
uniprot id: A0A0K2H0U8
names: Similarity
messages: Belongs to the peptidase C40 family.

1408189:CLAC RS01095
gene id: 1408189:CLAC_RS01095
uniprot id: A0A0K2GY00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1408189:CLAC RS02630
gene id: 1408189:CLAC_RS02630
uniprot id: A0A0K2GYF8
names: Similarity
messages: Belongs to the HypD family.

1408189:CLAC RS01980
gene id: 1408189:CLAC_RS01980
uniprot id: A0A0K2GY40
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS06820
gene id: 1408189:CLAC_RS06820
uniprot id: A0A0K2H0N9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS09705
gene id: 1408189:CLAC_RS09705
uniprot id: A0A0K2H1M6
names: Similarity
messages: Belongs to the GcvT family.

1408189:CLAC RS11890
gene id: 1408189:CLAC_RS11890
uniprot id: A0A0K2H2Q2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1408189:CLAC RS10150
gene id: 1408189:CLAC_RS10150
uniprot id: A0A0K2H1U4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1408189:CLAC RS06250
gene id: 1408189:CLAC_RS06250
uniprot id: A0A0K2H0F4
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS11430
gene id: 1408189:CLAC_RS11430
uniprot id: A0A0K2H2G1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1408189:CLAC RS05975
gene id: 1408189:CLAC_RS05975
uniprot id: A0A0K2H0X6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS04215
gene id: 1408189:CLAC_RS04215
uniprot id: A0A0K2GZD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1408189:CLAC RS05520
gene id: 1408189:CLAC_RS05520
uniprot id: A0A0K2H0Q9
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1408189:CLAC RS10995
gene id: 1408189:CLAC_RS10995
uniprot id: A0A0K2H291
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1408189:CLAC RS06010
gene id: 1408189:CLAC_RS06010
uniprot id: A0A0K2H0B4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1408189:CLAC RS06335
gene id: 1408189:CLAC_RS06335
uniprot id: A0A0K2H070
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1408189:CLAC RS07615
gene id: 1408189:CLAC_RS07615
uniprot id: A0A0K2H100
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1408189:CLAC RS02385
gene id: 1408189:CLAC_RS02385
uniprot id: A0A0K2GYB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1408189:CLAC RS05350
gene id: 1408189:CLAC_RS05350
uniprot id: A0A0K2H0N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1408189:CLAC RS02635
gene id: 1408189:CLAC_RS02635
uniprot id: A0A0K2GZD2
names: Similarity
messages: Belongs to the HupF/HypC family.

1408189:CLAC RS04425
gene id: 1408189:CLAC_RS04425
uniprot id: A0A0K2GZ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1408189:CLAC RS08740
gene id: 1408189:CLAC_RS08740
uniprot id: A0A0K2H1A1
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1408189:CLAC RS09755
gene id: 1408189:CLAC_RS09755
uniprot id: A0A0K2H1M7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1408189:CLAC RS02460
gene id: 1408189:CLAC_RS02460
uniprot id: A0A0K2GZA6
names: Similarity
messages: Belongs to the peptidase C40 family.

1408189:CLAC RS08875
gene id: 1408189:CLAC_RS08875
uniprot id: A0A0K2H2A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1408189:CLAC RS00675
gene id: 1408189:CLAC_RS00675
uniprot id: A0A0K2GYD6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS03720
gene id: 1408189:CLAC_RS03720
uniprot id: A0A0K2GYW4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1408189:CLAC RS01260
gene id: 1408189:CLAC_RS01260
uniprot id: A0A0K2GXR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408189:CLAC RS05770
gene id: 1408189:CLAC_RS05770
uniprot id: A0A0K2H0U1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1408189:CLAC RS02660
gene id: 1408189:CLAC_RS02660
uniprot id: A0A0K2GZD7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1408189:CLAC RS07985
gene id: 1408189:CLAC_RS07985
uniprot id: A0A0K2H1V2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1408189:CLAC RS06005
gene id: 1408189:CLAC_RS06005
uniprot id: A0A0K2GZZ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1408189:CLAC RS02020
gene id: 1408189:CLAC_RS02020
uniprot id: A0A0K2GY44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1408189:CLAC RS09265
gene id: 1408189:CLAC_RS09265
uniprot id: A0A0K2H2G0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1408189:CLAC RS02565
gene id: 1408189:CLAC_RS02565
uniprot id: A0A0K2GYE3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1408189:CLAC RS07100
gene id: 1408189:CLAC_RS07100
uniprot id: A0A0K2H0T5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1408189:CLAC RS11500
gene id: 1408189:CLAC_RS11500
uniprot id: A0A0K2H3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1408189:CLAC RS01505
gene id: 1408189:CLAC_RS01505
uniprot id: A0A0K2GXW1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1408189:CLAC RS01950
gene id: 1408189:CLAC_RS01950
uniprot id: A0A0K2GY35
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1408189:CLAC RS00125
gene id: 1408189:CLAC_RS00125
uniprot id: A0A0K2GX86
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS07425
gene id: 1408189:CLAC_RS07425
uniprot id: A0A0K2H1I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1408189:CLAC RS01945
gene id: 1408189:CLAC_RS01945
uniprot id: A0A0K2GZ03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1408189:CLAC RS10005
gene id: 1408189:CLAC_RS10005
uniprot id: A0A0K2H1R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1408189:CLAC RS06535
gene id: 1408189:CLAC_RS06535
uniprot id: A0A0K2H152
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS02440
gene id: 1408189:CLAC_RS02440
uniprot id: A0A0K2GYC3
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS06055
gene id: 1408189:CLAC_RS06055
uniprot id: A0A0K2H006
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1408189:CLAC RS06760
gene id: 1408189:CLAC_RS06760
uniprot id: A0A0K2H0N0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1408189:CLAC RS08235
gene id: 1408189:CLAC_RS08235
uniprot id: A0A0K2H112
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1408189:CLAC RS06625
gene id: 1408189:CLAC_RS06625
uniprot id: A0A0K2H0A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1408189:CLAC RS00760
gene id: 1408189:CLAC_RS00760
uniprot id: A0A0K2GXJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1408189:CLAC RS02095
gene id: 1408189:CLAC_RS02095
uniprot id: A0A0K2GY62
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1408189:CLAC RS11545
gene id: 1408189:CLAC_RS11545
uniprot id: A0A0K2H2T5
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS12020
gene id: 1408189:CLAC_RS12020
uniprot id: A0A0K2H2R5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS08350
gene id: 1408189:CLAC_RS08350
uniprot id: A0A0K2H1E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS05205
gene id: 1408189:CLAC_RS05205
uniprot id: A0A0K2GZL5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1408189:CLAC RS04060
gene id: 1408189:CLAC_RS04060
uniprot id: A0A0K2GZ06
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1408189:CLAC RS01990
gene id: 1408189:CLAC_RS01990
uniprot id: A0A0K2GY39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1408189:CLAC RS11980
gene id: 1408189:CLAC_RS11980
uniprot id: A0A0K2H2Q3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS05850
gene id: 1408189:CLAC_RS05850
uniprot id: A0A0K2H0V5
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS05600
gene id: 1408189:CLAC_RS05600
uniprot id: A0A0K2GZT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1408189:CLAC RS08820
gene id: 1408189:CLAC_RS08820
uniprot id: A0A0K2H2A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1408189:CLAC RS08060
gene id: 1408189:CLAC_RS08060
uniprot id: A0A0K2H0Z7
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS09370
gene id: 1408189:CLAC_RS09370
uniprot id: A0A0K2H1J0
names: Similarity
messages: Belongs to the AccD/PCCB family.

1408189:CLAC RS02010
gene id: 1408189:CLAC_RS02010
uniprot id: A0A0K2GY46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1408189:CLAC RS05355
gene id: 1408189:CLAC_RS05355
uniprot id: A0A0K2GZP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1408189:CLAC RS10435
gene id: 1408189:CLAC_RS10435
uniprot id: A0A0K2H1Y2
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1408189:CLAC RS03635
gene id: 1408189:CLAC_RS03635
uniprot id: A0A0K2GYU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1408189:CLAC RS02435
gene id: 1408189:CLAC_RS02435
uniprot id: A0A0K2GZA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS09970
gene id: 1408189:CLAC_RS09970
uniprot id: A0A0K2H1Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1408189:CLAC RS03105
gene id: 1408189:CLAC_RS03105
uniprot id: A0A0K2GZK8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1408189:CLAC RS04240
gene id: 1408189:CLAC_RS04240
uniprot id: A0A0K2GZE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1408189:CLAC RS08660
gene id: 1408189:CLAC_RS08660
uniprot id: A0A0K2H1J3
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS00010
gene id: 1408189:CLAC_RS00010
uniprot id: A0A0K2GY50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1408189:CLAC RS02285
gene id: 1408189:CLAC_RS02285
uniprot id: A0A0K2GY98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1408189:CLAC RS01885
gene id: 1408189:CLAC_RS01885
uniprot id: A0A0K2GY18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1408189:CLAC RS01920
gene id: 1408189:CLAC_RS01920
uniprot id: A0A0K2GYZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1408189:CLAC RS04705
gene id: 1408189:CLAC_RS04705
uniprot id: A0A0K2GZC4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1408189:CLAC RS01905
gene id: 1408189:CLAC_RS01905
uniprot id: A0A0K2GYC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1408189:CLAC RS06065
gene id: 1408189:CLAC_RS06065
uniprot id: A0A0K2H022
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1408189:CLAC RS05425
gene id: 1408189:CLAC_RS05425
uniprot id: A0A0K2GZR0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408189:CLAC RS10590
gene id: 1408189:CLAC_RS10590
uniprot id: A0A0K2H2Y3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1408189:CLAC RS08920
gene id: 1408189:CLAC_RS08920
uniprot id: A0A0K2H1D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1408189:CLAC RS03005
gene id: 1408189:CLAC_RS03005
uniprot id: A0A0K2GZJ0
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1408189:CLAC RS01925
gene id: 1408189:CLAC_RS01925
uniprot id: A0A0K2GY30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1408189:CLAC RS01795
gene id: 1408189:CLAC_RS01795
uniprot id: A0A0K2GY99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1408189:CLAC RS09710
gene id: 1408189:CLAC_RS09710
uniprot id: A0A0K2H1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1408189:CLAC RS05150
gene id: 1408189:CLAC_RS05150
uniprot id: A0A0K2GZK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1408189:CLAC RS07900
gene id: 1408189:CLAC_RS07900
uniprot id: A0A0K2H0W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1408189:CLAC RS12090
gene id: 1408189:CLAC_RS12090
uniprot id: A0A0K2H2S2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1408189:CLAC RS10465
gene id: 1408189:CLAC_RS10465
uniprot id: A0A0K2H1Y7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1408189:CLAC RS10230
gene id: 1408189:CLAC_RS10230
uniprot id: A0A0K2H1W1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1408189:CLAC RS08635
gene id: 1408189:CLAC_RS08635
uniprot id: A0A0K2H1I9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1408189:CLAC RS06050
gene id: 1408189:CLAC_RS06050
uniprot id: A0A0K2H0Z0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1408189:CLAC RS04965
gene id: 1408189:CLAC_RS04965
uniprot id: A0A0K2GZQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1408189:CLAC RS00780
gene id: 1408189:CLAC_RS00780
uniprot id: A0A0K2GXJ1
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS08880
gene id: 1408189:CLAC_RS08880
uniprot id: A0A0K2H1C3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1408189:CLAC RS02485
gene id: 1408189:CLAC_RS02485
uniprot id: A0A0K2GYD2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1408189:CLAC RS07530
gene id: 1408189:CLAC_RS07530
uniprot id: A0A0K2H0Y4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS08095
gene id: 1408189:CLAC_RS08095
uniprot id: A0A0K2H0Z3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1408189:CLAC RS02760
gene id: 1408189:CLAC_RS02760
uniprot id: A0A0K2GYH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1408189:CLAC RS02670
gene id: 1408189:CLAC_RS02670
uniprot id: A0A0K2GYS0
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1408189:CLAC RS07635
gene id: 1408189:CLAC_RS07635
uniprot id: A0A0K2H0P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1408189:CLAC RS05220
gene id: 1408189:CLAC_RS05220
uniprot id: A0A0K2H0I6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS04330
gene id: 1408189:CLAC_RS04330
uniprot id: A0A0K2GZG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS06685
gene id: 1408189:CLAC_RS06685
uniprot id: A0A0K2H0L7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1408189:CLAC RS12095
gene id: 1408189:CLAC_RS12095
uniprot id: A0A0K2H319
names: Similarity
messages: Belongs to the thioredoxin family.

1408189:CLAC RS10110
gene id: 1408189:CLAC_RS10110
uniprot id: A0A0K2H1T1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1408189:CLAC RS06025
gene id: 1408189:CLAC_RS06025
uniprot id: A0A0K2H0Y5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1408189:CLAC RS02315
gene id: 1408189:CLAC_RS02315
uniprot id: A0A0K2GZ84
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1408189:CLAC RS04535
gene id: 1408189:CLAC_RS04535
uniprot id: A0A0K2GZ80
names: Similarity
messages: Belongs to the UPF0045 family.

1408189:CLAC RS08365
gene id: 1408189:CLAC_RS08365
uniprot id: A0A0K2H233
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1408189:CLAC RS11710
gene id: 1408189:CLAC_RS11710
uniprot id: A0A0K2H2M5
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1408189:CLAC RS11875
gene id: 1408189:CLAC_RS11875
uniprot id: A0A0K2H2P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1408189:CLAC RS06100
gene id: 1408189:CLAC_RS06100
uniprot id: A0A0K2H0Z8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1408189:CLAC RS06575
gene id: 1408189:CLAC_RS06575
uniprot id: A0A0K2H0B2
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1408189:CLAC RS00755
gene id: 1408189:CLAC_RS00755
uniprot id: A0A0K2GXI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1408189:CLAC RS10535
gene id: 1408189:CLAC_RS10535
uniprot id: A0A0K2H2X3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1408189:CLAC RS10740
gene id: 1408189:CLAC_RS10740
uniprot id: A0A0K2H244
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS08280
gene id: 1408189:CLAC_RS08280
uniprot id: A0A0K2H136
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1408189:CLAC RS10705
gene id: 1408189:CLAC_RS10705
uniprot id: A0A0K2H231
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1408189:CLAC RS07920
gene id: 1408189:CLAC_RS07920
uniprot id: A0A0K2H146
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1408189:CLAC RS08900
gene id: 1408189:CLAC_RS08900
uniprot id: A0A0K2H1C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1408189:CLAC RS02015
gene id: 1408189:CLAC_RS02015
uniprot id: A0A0K2GYE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1408189:CLAC RS11130
gene id: 1408189:CLAC_RS11130
uniprot id: A0A0K2H382
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1408189:CLAC RS08240
gene id: 1408189:CLAC_RS08240
uniprot id: A0A0K2H1B0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1408189:CLAC RS08395
gene id: 1408189:CLAC_RS08395
uniprot id: A0A0K2H148
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1408189:CLAC RS10355
gene id: 1408189:CLAC_RS10355
uniprot id: A0A0K2H2U2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1408189:CLAC RS09255
gene id: 1408189:CLAC_RS09255
uniprot id: A0A0K2H1I3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1408189:CLAC RS00235
gene id: 1408189:CLAC_RS00235
uniprot id: A0A0K2GXB2
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS06630
gene id: 1408189:CLAC_RS06630
uniprot id: A0A0K2H0L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1408189:CLAC RS02085
gene id: 1408189:CLAC_RS02085
uniprot id: A0A0K2GY58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1408189:CLAC RS07830
gene id: 1408189:CLAC_RS07830
uniprot id: A0A0K2H0U3
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

1408189:CLAC RS11840
gene id: 1408189:CLAC_RS11840
uniprot id: A0A0K2H2N8
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1408189:CLAC RS02390
gene id: 1408189:CLAC_RS02390
uniprot id: A0A0K2GYB8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1408189:CLAC RS03830
gene id: 1408189:CLAC_RS03830
uniprot id: A0A0K2GYY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1408189:CLAC RS05160
gene id: 1408189:CLAC_RS05160
uniprot id: A0A0K2GZJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1408189:CLAC RS05125
gene id: 1408189:CLAC_RS05125
uniprot id: A0A0K2GZJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1408189:CLAC RS11170
gene id: 1408189:CLAC_RS11170
uniprot id: A0A0K2H2B6
names: Similarity
messages: Belongs to the HIBADH-related family.

1408189:CLAC RS08160
gene id: 1408189:CLAC_RS08160
uniprot id: A0A0K2H1Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1408189:CLAC RS02360
gene id: 1408189:CLAC_RS02360
uniprot id: A0A0K2GYB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1408189:CLAC RS09805
gene id: 1408189:CLAC_RS09805
uniprot id: A0A0K2H1Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1408189:CLAC RS06885
gene id: 1408189:CLAC_RS06885
uniprot id: A0A0K2H0E4
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS06075
gene id: 1408189:CLAC_RS06075
uniprot id: A0A0K2H0Z4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1408189:CLAC RS00840
gene id: 1408189:CLAC_RS00840
uniprot id: A0A0K2GXJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS02230
gene id: 1408189:CLAC_RS02230
uniprot id: A0A0K2GZ70
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS00185
gene id: 1408189:CLAC_RS00185
uniprot id: A0A0K2H2R7
names: Similarity
messages: Belongs to the YciI family.

1408189:CLAC RS02705
gene id: 1408189:CLAC_RS02705
uniprot id: A0A0K2GYH3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1408189:CLAC RS04670
gene id: 1408189:CLAC_RS04670
uniprot id: A0A0K2GZL7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1408189:CLAC RS02865
gene id: 1408189:CLAC_RS02865
uniprot id: A0A0K2GZG7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1408189:CLAC RS03470
gene id: 1408189:CLAC_RS03470
uniprot id: A0A0K2GYS2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1408189:CLAC RS00910
gene id: 1408189:CLAC_RS00910
uniprot id: A0A0K2GXX3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1408189:CLAC RS10560
gene id: 1408189:CLAC_RS10560
uniprot id: A0A0K2H2X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS09975
gene id: 1408189:CLAC_RS09975
uniprot id: A0A0K2H2N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1408189:CLAC RS10065
gene id: 1408189:CLAC_RS10065
uniprot id: A0A0K2H1U3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1408189:CLAC RS08860
gene id: 1408189:CLAC_RS08860
uniprot id: A0A0K2H1M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1408189:CLAC RS10430
gene id: 1408189:CLAC_RS10430
uniprot id: A0A0K2H1Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS03185
gene id: 1408189:CLAC_RS03185
uniprot id: A0A0K2GYP5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1408189:CLAC RS10970
gene id: 1408189:CLAC_RS10970
uniprot id: A0A0K2H284
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1408189:CLAC RS01650
gene id: 1408189:CLAC_RS01650
uniprot id: A0A0K2GYV3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1408189:CLAC RS02990
gene id: 1408189:CLAC_RS02990
uniprot id: A0A0K2GYX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1408189:CLAC RS04740
gene id: 1408189:CLAC_RS04740
uniprot id: A0A0K2H098
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1408189:CLAC RS01090
gene id: 1408189:CLAC_RS01090
uniprot id: A0A0K2GXN8
names: Subcellular Location Annotation
messages: Cytoplasm

1408189:CLAC RS10050
gene id: 1408189:CLAC_RS10050
uniprot id: A0A0K2H2Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1408189:CLAC RS02045
gene id: 1408189:CLAC_RS02045
uniprot id: A0A0K2GY49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1408189:CLAC RS11055
gene id: 1408189:CLAC_RS11055
uniprot id: A0A0K2H371
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1408189:CLAC RS10960
gene id: 1408189:CLAC_RS10960
uniprot id: A0A0K2H286
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1408189:CLAC RS01800
gene id: 1408189:CLAC_RS01800
uniprot id: A0A0K2GY03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1408189:CLAC RS09300
gene id: 1408189:CLAC_RS09300
uniprot id: A0A0K2H1I1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1408189:CLAC RS07565
gene id: 1408189:CLAC_RS07565
uniprot id: A0A0K2H0P0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1408189:CLAC RS09330
gene id: 1408189:CLAC_RS09330
uniprot id: A0A0K2H1U1
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS09325
gene id: 1408189:CLAC_RS09325
uniprot id: A0A0K2H1I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1408189:CLAC RS06355
gene id: 1408189:CLAC_RS06355
uniprot id: A0A0K2H130
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1408189:CLAC RS05030
gene id: 1408189:CLAC_RS05030
uniprot id: A0A0K2GZI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1408189:CLAC RS05375
gene id: 1408189:CLAC_RS05375
uniprot id: A0A0K2H0N7
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS01825
gene id: 1408189:CLAC_RS01825
uniprot id: A0A0K2GY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS04450
gene id: 1408189:CLAC_RS04450
uniprot id: A0A0K2GZ73
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS03485
gene id: 1408189:CLAC_RS03485
uniprot id: A0A0K2GYR9
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1408189:CLAC RS06845
gene id: 1408189:CLAC_RS06845
uniprot id: A0A0K2H0E0
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1408189:CLAC RS08525
gene id: 1408189:CLAC_RS08525
uniprot id: A0A0K2H184
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

1408189:CLAC RS00820
gene id: 1408189:CLAC_RS00820
uniprot id: A0A0K2GXK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1408189:CLAC RS07480
gene id: 1408189:CLAC_RS07480
uniprot id: A0A0K2H0L8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1408189:CLAC RS07735
gene id: 1408189:CLAC_RS07735
uniprot id: A0A0K2H0R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS05880
gene id: 1408189:CLAC_RS05880
uniprot id: A0A0K2GZX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1408189:CLAC RS11275
gene id: 1408189:CLAC_RS11275
uniprot id: A0A0K2H2C0
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS01995
gene id: 1408189:CLAC_RS01995
uniprot id: A0A0K2GY43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1408189:CLAC RS12060
gene id: 1408189:CLAC_RS12060
uniprot id: A0A0K2H2R8
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1408189:CLAC RS06585
gene id: 1408189:CLAC_RS06585
uniprot id: A0A0K2H161
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS07825
gene id: 1408189:CLAC_RS07825
uniprot id: A0A0K2H0V1
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1408189:CLAC RS11835
gene id: 1408189:CLAC_RS11835
uniprot id: A0A0K2H2Y5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1408189:CLAC RS03505
gene id: 1408189:CLAC_RS03505
uniprot id: A0A0K2GZ31
names: Similarity
messages: Belongs to the peptidase M1 family.

1408189:CLAC RS04860
gene id: 1408189:CLAC_RS04860
uniprot id: A0A0K2GZN5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1408189:CLAC RS06380
gene id: 1408189:CLAC_RS06380
uniprot id: A0A0K2H132
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1408189:CLAC RS01400
gene id: 1408189:CLAC_RS01400
uniprot id: A0A0K2GYQ4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1408189:CLAC RS08700
gene id: 1408189:CLAC_RS08700
uniprot id: A0A0K2H1A7
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1408189:CLAC RS08835
gene id: 1408189:CLAC_RS08835
uniprot id: A0A0K2H1M0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS04555
gene id: 1408189:CLAC_RS04555
uniprot id: A0A0K2GZ94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1408189:CLAC RS10030
gene id: 1408189:CLAC_RS10030
uniprot id: A0A0K2H1S3
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1408189:CLAC RS07405
gene id: 1408189:CLAC_RS07405
uniprot id: A0A0K2H0K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1408189:CLAC RS07370
gene id: 1408189:CLAC_RS07370
uniprot id: A0A0K2H0K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS07070
gene id: 1408189:CLAC_RS07070
uniprot id: A0A0K2H0J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1408189:CLAC RS08630
gene id: 1408189:CLAC_RS08630
uniprot id: A0A0K2H180
names: Similarity
messages: Belongs to the FBPase class 2 family.

1408189:CLAC RS00015
gene id: 1408189:CLAC_RS00015
uniprot id: A0A0K2GX72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1408189:CLAC RS03580
gene id: 1408189:CLAC_RS03580
uniprot id: A0A0K2GZ42
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1408189:CLAC RS06275
gene id: 1408189:CLAC_RS06275
uniprot id: A0A0K2H0F8
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1408189:CLAC RS06305
gene id: 1408189:CLAC_RS06305
uniprot id: A0A0K2H0G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1408189:CLAC RS07895
gene id: 1408189:CLAC_RS07895
uniprot id: A0A0K2H141
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1408189:CLAC RS09775
gene id: 1408189:CLAC_RS09775
uniprot id: A0A0K2H1Y8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1408189:CLAC RS06945
gene id: 1408189:CLAC_RS06945
uniprot id: A0A0K2H0R0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1408189:CLAC RS02910
gene id: 1408189:CLAC_RS02910
uniprot id: A0A0K2GYJ9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1408189:CLAC RS06980
gene id: 1408189:CLAC_RS06980
uniprot id: A0A0K2H0H6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1408189:CLAC RS02850
gene id: 1408189:CLAC_RS02850
uniprot id: A0A0K2GYJ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1408189:CLAC RS08725
gene id: 1408189:CLAC_RS08725
uniprot id: A0A0K2H1B2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS11480
gene id: 1408189:CLAC_RS11480
uniprot id: A0A0K2H2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cell inner membrane
messages: Membrane

1408189:CLAC RS04715
gene id: 1408189:CLAC_RS04715
uniprot id: A0A0K2H093
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS03610
gene id: 1408189:CLAC_RS03610
uniprot id: A0A0K2GYU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1408189:CLAC RS02665
gene id: 1408189:CLAC_RS02665
uniprot id: A0A0K2GYG2
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1408189:CLAC RS01595
gene id: 1408189:CLAC_RS01595
uniprot id: A0A0K2GXX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1408189:CLAC RS05800
gene id: 1408189:CLAC_RS05800
uniprot id: A0A0K2H0U6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1408189:CLAC RS06150
gene id: 1408189:CLAC_RS06150
uniprot id: A0A0K2H106
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1408189:CLAC RS07700
gene id: 1408189:CLAC_RS07700
uniprot id: A0A0K2H0R7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1408189:CLAC RS00690
gene id: 1408189:CLAC_RS00690
uniprot id: A0A0K2GXH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1408189:CLAC RS03690
gene id: 1408189:CLAC_RS03690
uniprot id: A0A0K2GYV9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1408189:CLAC RS08805
gene id: 1408189:CLAC_RS08805
uniprot id: A0A0K2H1L5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1408189:CLAC RS05180
gene id: 1408189:CLAC_RS05180
uniprot id: A0A0K2H0I1
names: Similarity
messages: Belongs to the MQO family.

1408189:CLAC RS07965
gene id: 1408189:CLAC_RS07965
uniprot id: A0A0K2H0W5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1408189:CLAC RS11050
gene id: 1408189:CLAC_RS11050
uniprot id: A0A0K2H283
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1408189:CLAC RS11105
gene id: 1408189:CLAC_RS11105
uniprot id: A0A0K2H2I3
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS04580
gene id: 1408189:CLAC_RS04580
uniprot id: A0A0K2GZ99
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1408189:CLAC RS03620
gene id: 1408189:CLAC_RS03620
uniprot id: A0A0K2GZP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1408189:CLAC RS11505
gene id: 1408189:CLAC_RS11505
uniprot id: A0A0K2H2H6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1408189:CLAC RS08780
gene id: 1408189:CLAC_RS08780
uniprot id: A0A0K2H1C0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1408189:CLAC RS00070
gene id: 1408189:CLAC_RS00070
uniprot id: A0A0K2GX76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1408189:CLAC RS01675
gene id: 1408189:CLAC_RS01675
uniprot id: A0A0K2GYW0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1408189:CLAC RS05285
gene id: 1408189:CLAC_RS05285
uniprot id: A0A0K2GZZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1408189:CLAC RS07945
gene id: 1408189:CLAC_RS07945
uniprot id: A0A0K2H154
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1408189:CLAC RS07715
gene id: 1408189:CLAC_RS07715
uniprot id: A0A0K2H118
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1408189:CLAC RS11515
gene id: 1408189:CLAC_RS11515
uniprot id: A0A0K2H2I6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1408189:CLAC RS06540
gene id: 1408189:CLAC_RS06540
uniprot id: A0A0K2H092
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1408189:CLAC RS01465
gene id: 1408189:CLAC_RS01465
uniprot id: A0A0K2GXU8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1408189:CLAC RS05680
gene id: 1408189:CLAC_RS05680
uniprot id: A0A0K2GZV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1408189:CLAC RS05930
gene id: 1408189:CLAC_RS05930
uniprot id: A0A0K2GZY4
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1408189:CLAC RS06475
gene id: 1408189:CLAC_RS06475
uniprot id: A0A0K2H083
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1408189:CLAC RS03710
gene id: 1408189:CLAC_RS03710
uniprot id: A0A0K2GZ62
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS01890
gene id: 1408189:CLAC_RS01890
uniprot id: A0A0K2GY25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1408189:CLAC RS07350
gene id: 1408189:CLAC_RS07350
uniprot id: A0A0K2H0J7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1408189:CLAC RS05065
gene id: 1408189:CLAC_RS05065
uniprot id: A0A0K2GZS6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1408189:CLAC RS03100
gene id: 1408189:CLAC_RS03100
uniprot id: A0A0K2GYN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1408189:CLAC RS07765
gene id: 1408189:CLAC_RS07765
uniprot id: A0A0K2H125
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1408189:CLAC RS06970
gene id: 1408189:CLAC_RS06970
uniprot id: A0A0K2H0G0
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1408189:CLAC RS08450
gene id: 1408189:CLAC_RS08450
uniprot id: A0A0K2H158
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1408189:CLAC RS10090
gene id: 1408189:CLAC_RS10090
uniprot id: A0A0K2H1T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1408189:CLAC RS04895
gene id: 1408189:CLAC_RS04895
uniprot id: A0A0K2GZF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1408189:CLAC RS05550
gene id: 1408189:CLAC_RS05550
uniprot id: A0A0K2H0R2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1408189:CLAC RS03020
gene id: 1408189:CLAC_RS03020
uniprot id: A0A0K2GYM0
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1408189:CLAC RS08460
gene id: 1408189:CLAC_RS08460
uniprot id: A0A0K2H157
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS01900
gene id: 1408189:CLAC_RS01900
uniprot id: A0A0K2GY24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1408189:CLAC RS05965
gene id: 1408189:CLAC_RS05965
uniprot id: A0A0K2H002
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1408189:CLAC RS07025
gene id: 1408189:CLAC_RS07025
uniprot id: A0A0K2H1D0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1408189:CLAC RS05820
gene id: 1408189:CLAC_RS05820
uniprot id: A0A0K2GZW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS04505
gene id: 1408189:CLAC_RS04505
uniprot id: A0A0K2H040
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1408189:CLAC RS09800
gene id: 1408189:CLAC_RS09800
uniprot id: A0A0K2H1Z3
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1408189:CLAC RS11555
gene id: 1408189:CLAC_RS11555
uniprot id: A0A0K2H2I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1408189:CLAC RS01290
gene id: 1408189:CLAC_RS01290
uniprot id: A0A0K2GXS2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1408189:CLAC RS00620
gene id: 1408189:CLAC_RS00620
uniprot id: A0A0K2GXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1408189:CLAC RS00025
gene id: 1408189:CLAC_RS00025
uniprot id: A0A0K2GX75
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1408189:CLAC RS04435
gene id: 1408189:CLAC_RS04435
uniprot id: A0A0K2GZ60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1408189:CLAC RS11825
gene id: 1408189:CLAC_RS11825
uniprot id: A0A0K2H2M2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

1408189:CLAC RS01910
gene id: 1408189:CLAC_RS01910
uniprot id: A0A0K2GY23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1408189:CLAC RS11760
gene id: 1408189:CLAC_RS11760
uniprot id: A0A0K2H2X0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1408189:CLAC RS05920
gene id: 1408189:CLAC_RS05920
uniprot id: A0A0K2GZY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1408189:CLAC RS08760
gene id: 1408189:CLAC_RS08760
uniprot id: A0A0K2H292
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1408189:CLAC RS06395
gene id: 1408189:CLAC_RS06395
uniprot id: A0A0K2H081
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1408189:CLAC RS04490
gene id: 1408189:CLAC_RS04490
uniprot id: A0A0K2GZI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1408189:CLAC RS05290
gene id: 1408189:CLAC_RS05290
uniprot id: A0A0K2GZP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1408189:CLAC RS06465
gene id: 1408189:CLAC_RS06465
uniprot id: A0A0K2H079
names: Similarity
messages: Belongs to the CobH/CbiC family.

1408189:CLAC RS04010
gene id: 1408189:CLAC_RS04010
uniprot id: A0A0K2GZ00
names: Similarity
messages: Belongs to the peptidase M18 family.

1408189:CLAC RS04815
gene id: 1408189:CLAC_RS04815
uniprot id: A0A0K2H0A9
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

1408189:CLAC RS08840
gene id: 1408189:CLAC_RS08840
uniprot id: A0A0K2H1C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1408189:CLAC RS10660
gene id: 1408189:CLAC_RS10660
uniprot id: A0A0K2H228
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1408189:CLAC RS10695
gene id: 1408189:CLAC_RS10695
uniprot id: A0A0K2H223
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1408189:CLAC RS07690
gene id: 1408189:CLAC_RS07690
uniprot id: A0A0K2H113
names: Similarity
messages: Belongs to the YggT family.

1408189:CLAC RS05895
gene id: 1408189:CLAC_RS05895
uniprot id: A0A0K2GZY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1408189:CLAC RS06975
gene id: 1408189:CLAC_RS06975
uniprot id: A0A0K2H0R5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1408189:CLAC RS00900
gene id: 1408189:CLAC_RS00900
uniprot id: A0A0K2GXK6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1408189:CLAC RS06940
gene id: 1408189:CLAC_RS06940
uniprot id: A0A0K2H0F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1408189:CLAC RS07540
gene id: 1408189:CLAC_RS07540
uniprot id: A0A0K2H0N5
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS11560
gene id: 1408189:CLAC_RS11560
uniprot id: A0A0K2H3I2
names: Similarity
messages: Belongs to the UPF0237 family.

1408189:CLAC RS04220
gene id: 1408189:CLAC_RS04220
uniprot id: A0A0K2GZ40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1408189:CLAC RS05200
gene id: 1408189:CLAC_RS05200
uniprot id: A0A0K2GZV6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1408189:CLAC RS00420
gene id: 1408189:CLAC_RS00420
uniprot id: A0A0K2GXE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1408189:CLAC RS05090
gene id: 1408189:CLAC_RS05090
uniprot id: A0A0K2GZT2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1408189:CLAC RS12125
gene id: 1408189:CLAC_RS12125
uniprot id: A0A0K2H324
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1408189:CLAC RS02605
gene id: 1408189:CLAC_RS02605
uniprot id: A0A0K2GYF3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1408189:CLAC RS03940
gene id: 1408189:CLAC_RS03940
uniprot id: A0A0K2GYZ0
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1408189:CLAC RS04485
gene id: 1408189:CLAC_RS04485
uniprot id: A0A0K2GZ69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1408189:CLAC RS04140
gene id: 1408189:CLAC_RS04140
uniprot id: A0A0K2GZC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1408189:CLAC RS10900
gene id: 1408189:CLAC_RS10900
uniprot id: A0A0K2H342
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1408189:CLAC RS02090
gene id: 1408189:CLAC_RS02090
uniprot id: A0A0K2GZ30
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1408189:CLAC RS08925
gene id: 1408189:CLAC_RS08925
uniprot id: A0A0K2H1C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1408189:CLAC RS07360
gene id: 1408189:CLAC_RS07360
uniprot id: A0A0K2H0V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS09900
gene id: 1408189:CLAC_RS09900
uniprot id: A0A0K2H1Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1408189:CLAC RS09985
gene id: 1408189:CLAC_RS09985
uniprot id: A0A0K2H214
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS10975
gene id: 1408189:CLAC_RS10975
uniprot id: A0A0K2H272
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1408189:CLAC RS01410
gene id: 1408189:CLAC_RS01410
uniprot id: A0A0K2GY51
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1408189:CLAC RS01350
gene id: 1408189:CLAC_RS01350
uniprot id: A0A0K2GYP4
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1408189:CLAC RS05110
gene id: 1408189:CLAC_RS05110
uniprot id: A0A0K2GZI6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1408189:CLAC RS09750
gene id: 1408189:CLAC_RS09750
uniprot id: A0A0K2H3Z1
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS02145
gene id: 1408189:CLAC_RS02145
uniprot id: A0A0K2GZ35
names: Similarity
messages: Belongs to the WXG100 family.

1408189:CLAC RS01455
gene id: 1408189:CLAC_RS01455
uniprot id: A0A0K2GXV1
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS00955
gene id: 1408189:CLAC_RS00955
uniprot id: A0A0K2GXL5
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS01040
gene id: 1408189:CLAC_RS01040
uniprot id: A0A0K2GXN6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1408189:CLAC RS05070
gene id: 1408189:CLAC_RS05070
uniprot id: A0A0K2GZI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1408189:CLAC RS07665
gene id: 1408189:CLAC_RS07665
uniprot id: A0A0K2H109
names: Similarity
messages: Belongs to the asparaginase 1 family.

1408189:CLAC RS01240
gene id: 1408189:CLAC_RS01240
uniprot id: A0A0K2GYM4
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS07675
gene id: 1408189:CLAC_RS07675
uniprot id: A0A0K2H0R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1408189:CLAC RS11335
gene id: 1408189:CLAC_RS11335
uniprot id: A0A0K2H3C0
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS03570
gene id: 1408189:CLAC_RS03570
uniprot id: A0A0K2GZN6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1408189:CLAC RS12135
gene id: 1408189:CLAC_RS12135
uniprot id: A0A0K2H2R3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1408189:CLAC RS03615
gene id: 1408189:CLAC_RS03615
uniprot id: A0A0K2GYU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1408189:CLAC RS00670
gene id: 1408189:CLAC_RS00670
uniprot id: A0A0K2GXH8
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS09880
gene id: 1408189:CLAC_RS09880
uniprot id: A0A0K2H203
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1408189:CLAC RS05745
gene id: 1408189:CLAC_RS05745
uniprot id: A0A0K2H0T7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1408189:CLAC RS06920
gene id: 1408189:CLAC_RS06920
uniprot id: A0A0K2H0Q5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS09765
gene id: 1408189:CLAC_RS09765
uniprot id: A0A0K2H1N6
names: Similarity
messages: Belongs to the AccD/PCCB family.

1408189:CLAC RS06410
gene id: 1408189:CLAC_RS06410
uniprot id: A0A0K2H071
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1408189:CLAC RS02945
gene id: 1408189:CLAC_RS02945
uniprot id: A0A0K2GYK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS08200
gene id: 1408189:CLAC_RS08200
uniprot id: A0A0K2H1A4
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS00865
gene id: 1408189:CLAC_RS00865
uniprot id: A0A0K2GXK2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS05940
gene id: 1408189:CLAC_RS05940
uniprot id: A0A0K2GZZ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1408189:CLAC RS09310
gene id: 1408189:CLAC_RS09310
uniprot id: A0A0K2H1J2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1408189:CLAC RS06815
gene id: 1408189:CLAC_RS06815
uniprot id: A0A0K2H0D6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1408189:CLAC RS08360
gene id: 1408189:CLAC_RS08360
uniprot id: A0A0K2H144
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1408189:CLAC RS05470
gene id: 1408189:CLAC_RS05470
uniprot id: A0A0K2H027
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1408189:CLAC RS00860
gene id: 1408189:CLAC_RS00860
uniprot id: A0A0K2GYG6
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1408189:CLAC RS10850
gene id: 1408189:CLAC_RS10850
uniprot id: A0A0K2H264
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1408189:CLAC RS10825
gene id: 1408189:CLAC_RS10825
uniprot id: A0A0K2H2E9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1408189:CLAC RS08565
gene id: 1408189:CLAC_RS08565
uniprot id: A0A0K2H178
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS11310
gene id: 1408189:CLAC_RS11310
uniprot id: A0A0K2H2E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

1408189:CLAC RS02290
gene id: 1408189:CLAC_RS02290
uniprot id: A0A0K2GZ79
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1408189:CLAC RS10630
gene id: 1408189:CLAC_RS10630
uniprot id: A0A0K2H2B5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1408189:CLAC RS03195
gene id: 1408189:CLAC_RS03195
uniprot id: A0A0K2GZ09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1408189:CLAC RS10770
gene id: 1408189:CLAC_RS10770
uniprot id: A0A0K2H248
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1408189:CLAC RS10260
gene id: 1408189:CLAC_RS10260
uniprot id: A0A0K2H1W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS05875
gene id: 1408189:CLAC_RS05875
uniprot id: A0A0K2H0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1408189:CLAC RS11970
gene id: 1408189:CLAC_RS11970
uniprot id: A0A0K2H2Q7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1408189:CLAC RS00145
gene id: 1408189:CLAC_RS00145
uniprot id: A0A0K2GY68
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1408189:CLAC RS10100
gene id: 1408189:CLAC_RS10100
uniprot id: A0A0K2H1U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1408189:CLAC RS02405
gene id: 1408189:CLAC_RS02405
uniprot id: A0A0K2GYM6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1408189:CLAC RS02950
gene id: 1408189:CLAC_RS02950
uniprot id: A0A0K2GZI1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1408189:CLAC RS00550
gene id: 1408189:CLAC_RS00550
uniprot id: A0A0K2GXR9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1408189:CLAC RS04890
gene id: 1408189:CLAC_RS04890
uniprot id: A0A0K2GZF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1408189:CLAC RS12110
gene id: 1408189:CLAC_RS12110
uniprot id: A0A0K2H2Q9
names: Similarity
messages: Belongs to the ParB family.

1408189:CLAC RS07110
gene id: 1408189:CLAC_RS07110
uniprot id: A0A0K2H0I9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1408189:CLAC RS04310
gene id: 1408189:CLAC_RS04310
uniprot id: A0A0K2GZ53
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS05565
gene id: 1408189:CLAC_RS05565
uniprot id: A0A0K2GZU0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS05495
gene id: 1408189:CLAC_RS05495
uniprot id: A0A0K2H032
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1408189:CLAC RS06950
gene id: 1408189:CLAC_RS06950
uniprot id: A0A0K2H0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1408189:CLAC RS05275
gene id: 1408189:CLAC_RS05275
uniprot id: A0A0K2H0J8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1408189:CLAC RS07930
gene id: 1408189:CLAC_RS07930
uniprot id: A0A0K2H0W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1408189:CLAC RS02500
gene id: 1408189:CLAC_RS02500
uniprot id: A0A0K2GYD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS04985
gene id: 1408189:CLAC_RS04985
uniprot id: A0A0K2GZG5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1408189:CLAC RS02305
gene id: 1408189:CLAC_RS02305
uniprot id: A0A0K2GYA4
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1408189:CLAC RS04730
gene id: 1408189:CLAC_RS04730
uniprot id: A0A0K2GZC9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1408189:CLAC RS06900
gene id: 1408189:CLAC_RS06900
uniprot id: A0A0K2H0F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS04145
gene id: 1408189:CLAC_RS04145
uniprot id: A0A0K2GZ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1408189:CLAC RS01195
gene id: 1408189:CLAC_RS01195
uniprot id: A0A0K2GXQ7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1408189:CLAC RS06300
gene id: 1408189:CLAC_RS06300
uniprot id: A0A0K2H051
names: Similarity
messages: Belongs to the UPF0098 family.

1408189:CLAC RS08455
gene id: 1408189:CLAC_RS08455
uniprot id: A0A0K2H247
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

1408189:CLAC RS08540
gene id: 1408189:CLAC_RS08540
uniprot id: A0A0K2H261
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1408189:CLAC RS03140
gene id: 1408189:CLAC_RS03140
uniprot id: A0A0K2H316
names: Similarity
messages: Belongs to the neocarzinostatin family.

1408189:CLAC RS04525
gene id: 1408189:CLAC_RS04525
uniprot id: A0A0K2GZ89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1408189:CLAC RS04735
gene id: 1408189:CLAC_RS04735
uniprot id: A0A0K2GZD1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1408189:CLAC RS05385
gene id: 1408189:CLAC_RS05385
uniprot id: A0A0K2H014
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1408189:CLAC RS04935
gene id: 1408189:CLAC_RS04935
uniprot id: A0A0K2GZF3
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1408189:CLAC RS03700
gene id: 1408189:CLAC_RS03700
uniprot id: A0A0K2GYV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1408189:CLAC RS10555
gene id: 1408189:CLAC_RS10555
uniprot id: A0A0K2H202
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS08325
gene id: 1408189:CLAC_RS08325
uniprot id: A0A0K2H140
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1408189:CLAC RS07465
gene id: 1408189:CLAC_RS07465
uniprot id: A0A0K2H0N1
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS02845
gene id: 1408189:CLAC_RS02845
uniprot id: A0A0K2GYJ0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1408189:CLAC RS01940
gene id: 1408189:CLAC_RS01940
uniprot id: A0A0K2GY34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1408189:CLAC RS05990
gene id: 1408189:CLAC_RS05990
uniprot id: A0A0K2H007
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1408189:CLAC RS03995
gene id: 1408189:CLAC_RS03995
uniprot id: A0A0K2GZ07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1408189:CLAC RS05330
gene id: 1408189:CLAC_RS05330
uniprot id: A0A0K2GZN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1408189:CLAC RS11180
gene id: 1408189:CLAC_RS11180
uniprot id: A0A0K2H392
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1408189:CLAC RS01775
gene id: 1408189:CLAC_RS01775
uniprot id: A0A0K2GY02
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1408189:CLAC RS05165
gene id: 1408189:CLAC_RS05165
uniprot id: A0A0K2GZU9
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS05845
gene id: 1408189:CLAC_RS05845
uniprot id: A0A0K2GZX3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1408189:CLAC RS02150
gene id: 1408189:CLAC_RS02150
uniprot id: A0A0K2GY67
names: Similarity
messages: Belongs to the WXG100 family.

1408189:CLAC RS02000
gene id: 1408189:CLAC_RS02000
uniprot id: A0A0K2GZ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1408189:CLAC RS00375
gene id: 1408189:CLAC_RS00375
uniprot id: A0A0K2GXP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1408189:CLAC RS07800
gene id: 1408189:CLAC_RS07800
uniprot id: A0A0K2H0U5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1408189:CLAC RS02960
gene id: 1408189:CLAC_RS02960
uniprot id: A0A0K2GYW8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1408189:CLAC RS06895
gene id: 1408189:CLAC_RS06895
uniprot id: A0A0K2H0G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1408189:CLAC RS04165
gene id: 1408189:CLAC_RS04165
uniprot id: A0A0K2GZ19
names: Similarity
messages: Belongs to the LOG family.

1408189:CLAC RS00205
gene id: 1408189:CLAC_RS00205
uniprot id: A0A0K2GXA8
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS08045
gene id: 1408189:CLAC_RS08045
uniprot id: A0A0K2H1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1408189:CLAC RS00275
gene id: 1408189:CLAC_RS00275
uniprot id: A0A0K2GXB0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1408189:CLAC RS00730
gene id: 1408189:CLAC_RS00730
uniprot id: A0A0K2GXI8
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS05780
gene id: 1408189:CLAC_RS05780
uniprot id: A0A0K2GZW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1408189:CLAC RS08180
gene id: 1408189:CLAC_RS08180
uniprot id: A0A0K2H120
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1408189:CLAC RS08230
gene id: 1408189:CLAC_RS08230
uniprot id: A0A0K2H1Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1408189:CLAC RS02200
gene id: 1408189:CLAC_RS02200
uniprot id: A0A0K2GY85
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1408189:CLAC RS04295
gene id: 1408189:CLAC_RS04295
uniprot id: A0A0K2H005
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1408189:CLAC RS02515
gene id: 1408189:CLAC_RS02515
uniprot id: A0A0K2GYD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1408189:CLAC RS01915
gene id: 1408189:CLAC_RS01915
uniprot id: A0A0K2GY29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1408189:CLAC RS00410
gene id: 1408189:CLAC_RS00410
uniprot id: A0A0K2H338
names: Similarity
messages: Belongs to the neocarzinostatin family.

1408189:CLAC RS12130
gene id: 1408189:CLAC_RS12130
uniprot id: A0A0K2H2S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1408189:CLAC RS07555
gene id: 1408189:CLAC_RS07555
uniprot id: A0A0K2H0Y9
names: Similarity
messages: Belongs to the AccD/PCCB family.

1408189:CLAC RS00445
gene id: 1408189:CLAC_RS00445
uniprot id: A0A0K2GXE5
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1408189:CLAC RS00635
gene id: 1408189:CLAC_RS00635
uniprot id: A0A0K2GXG5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1408189:CLAC RS02940
gene id: 1408189:CLAC_RS02940
uniprot id: A0A0K2GYK5
names: Similarity
messages: Belongs to the peptidase S16 family.

1408189:CLAC RS10235
gene id: 1408189:CLAC_RS10235
uniprot id: A0A0K2H1U7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1408189:CLAC RS02355
gene id: 1408189:CLAC_RS02355
uniprot id: A0A0K2GYL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1408189:CLAC RS04970
gene id: 1408189:CLAC_RS04970
uniprot id: A0A0K2GZH3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408189:CLAC RS07725
gene id: 1408189:CLAC_RS07725
uniprot id: A0A0K2H0S2
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS06235
gene id: 1408189:CLAC_RS06235
uniprot id: A0A0K2H044
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS03025
gene id: 1408189:CLAC_RS03025
uniprot id: A0A0K2GYM3
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS05530
gene id: 1408189:CLAC_RS05530
uniprot id: A0A0K2H036
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1408189:CLAC RS06935
gene id: 1408189:CLAC_RS06935
uniprot id: A0A0K2H1B8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1408189:CLAC RS08065
gene id: 1408189:CLAC_RS08065
uniprot id: A0A0K2H0Y8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1408189:CLAC RS01435
gene id: 1408189:CLAC_RS01435
uniprot id: A0A0K2GYQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS05485
gene id: 1408189:CLAC_RS05485
uniprot id: A0A0K2H0Q4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1408189:CLAC RS10265
gene id: 1408189:CLAC_RS10265
uniprot id: A0A0K2H1V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS04950
gene id: 1408189:CLAC_RS04950
uniprot id: A0A0K2GZG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1408189:CLAC RS04085
gene id: 1408189:CLAC_RS04085
uniprot id: A0A0K2GZX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1408189:CLAC RS00480
gene id: 1408189:CLAC_RS00480
uniprot id: A0A0K2GXE4
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1408189:CLAC RS08620
gene id: 1408189:CLAC_RS08620
uniprot id: A0A0K2H270
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1408189:CLAC RS03745
gene id: 1408189:CLAC_RS03745
uniprot id: A0A0K2GYW9
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS00845
gene id: 1408189:CLAC_RS00845
uniprot id: A0A0K2GXW3
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS09845
gene id: 1408189:CLAC_RS09845
uniprot id: A0A0K2H1P2
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1408189:CLAC RS04850
gene id: 1408189:CLAC_RS04850
uniprot id: A0A0K2H0B3
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS05870
gene id: 1408189:CLAC_RS05870
uniprot id: A0A0K2GZX7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1408189:CLAC RS11880
gene id: 1408189:CLAC_RS11880
uniprot id: A0A0K2H2N1
names: Similarity
messages: Belongs to the universal stress protein A family.

1408189:CLAC RS09315
gene id: 1408189:CLAC_RS09315
uniprot id: A0A0K2H1I0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1408189:CLAC RS10690
gene id: 1408189:CLAC_RS10690
uniprot id: A0A0K2H234
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1408189:CLAC RS03460
gene id: 1408189:CLAC_RS03460
uniprot id: A0A0K2GZ28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1408189:CLAC RS01700
gene id: 1408189:CLAC_RS01700
uniprot id: A0A0K2GY87
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1408189:CLAC RS05955
gene id: 1408189:CLAC_RS05955
uniprot id: A0A0K2GZY8
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1408189:CLAC RS05950
gene id: 1408189:CLAC_RS05950
uniprot id: A0A0K2H0X2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS11445
gene id: 1408189:CLAC_RS11445
uniprot id: A0A0K2H3E2
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1408189:CLAC RS09135
gene id: 1408189:CLAC_RS09135
uniprot id: A0A0K2H1F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

1408189:CLAC RS08915
gene id: 1408189:CLAC_RS08915
uniprot id: A0A0K2H1N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1408189:CLAC RS11330
gene id: 1408189:CLAC_RS11330
uniprot id: A0A0K2H2D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1408189:CLAC RS05015
gene id: 1408189:CLAC_RS05015
uniprot id: A0A0K2GZH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1408189:CLAC RS08380
gene id: 1408189:CLAC_RS08380
uniprot id: A0A0K2H160
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1408189:CLAC RS05650
gene id: 1408189:CLAC_RS05650
uniprot id: A0A0K2GZV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS05555
gene id: 1408189:CLAC_RS05555
uniprot id: A0A0K2GZS4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS10140
gene id: 1408189:CLAC_RS10140
uniprot id: A0A0K2H2R4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1408189:CLAC RS11670
gene id: 1408189:CLAC_RS11670
uniprot id: A0A0K2H2K0
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS07745
gene id: 1408189:CLAC_RS07745
uniprot id: A0A0K2H0T4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS02180
gene id: 1408189:CLAC_RS02180
uniprot id: A0A0K2GYI7
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1408189:CLAC RS03525
gene id: 1408189:CLAC_RS03525
uniprot id: A0A0K2GZN3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1408189:CLAC RS00490
gene id: 1408189:CLAC_RS00490
uniprot id: A0A0K2GXE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS00215
gene id: 1408189:CLAC_RS00215
uniprot id: A0A0K2GXA0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1408189:CLAC RS01230
gene id: 1408189:CLAC_RS01230
uniprot id: A0A0K2GXQ5
names: Cofactor
messages: Can also use Mn(2+) ion.

1408189:CLAC RS02840
gene id: 1408189:CLAC_RS02840
uniprot id: A0A0K2GYV0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1408189:CLAC RS09895
gene id: 1408189:CLAC_RS09895
uniprot id: A0A0K2H2M4
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS10595
gene id: 1408189:CLAC_RS10595
uniprot id: A0A0K2H213
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1408189:CLAC RS03095
gene id: 1408189:CLAC_RS03095
uniprot id: A0A0K2GYN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1408189:CLAC RS00155
gene id: 1408189:CLAC_RS00155
uniprot id: A0A0K2GX91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS10020
gene id: 1408189:CLAC_RS10020
uniprot id: A0A0K2H1R6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408189:CLAC RS10860
gene id: 1408189:CLAC_RS10860
uniprot id: A0A0K2H263
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1408189:CLAC RS10305
gene id: 1408189:CLAC_RS10305
uniprot id: A0A0K2H1W4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS08845
gene id: 1408189:CLAC_RS08845
uniprot id: A0A0K2H1B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1408189:CLAC RS10985
gene id: 1408189:CLAC_RS10985
uniprot id: A0A0K2H359
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS05560
gene id: 1408189:CLAC_RS05560
uniprot id: A0A0K2H041
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1408189:CLAC RS05115
gene id: 1408189:CLAC_RS05115
uniprot id: A0A0K2GZT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1408189:CLAC RS06390
gene id: 1408189:CLAC_RS06390
uniprot id: A0A0K2H0H7
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1408189:CLAC RS03585
gene id: 1408189:CLAC_RS03585
uniprot id: A0A0K2GYT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1408189:CLAC RS09890
gene id: 1408189:CLAC_RS09890
uniprot id: A0A0K2H1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1408189:CLAC RS07335
gene id: 1408189:CLAC_RS07335
uniprot id: A0A0K2H0K8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1408189:CLAC RS06070
gene id: 1408189:CLAC_RS06070
uniprot id: A0A0K2H013
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1408189:CLAC RS05905
gene id: 1408189:CLAC_RS05905
uniprot id: A0A0K2GZY0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS05245
gene id: 1408189:CLAC_RS05245
uniprot id: A0A0K2H0J2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1408189:CLAC RS09195
gene id: 1408189:CLAC_RS09195
uniprot id: A0A0K2H1R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1408189:CLAC RS07880
gene id: 1408189:CLAC_RS07880
uniprot id: A0A0K2H0V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1408189:CLAC RS10700
gene id: 1408189:CLAC_RS10700
uniprot id: A0A0K2H306
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1408189:CLAC RS05985
gene id: 1408189:CLAC_RS05985
uniprot id: A0A0K2H0A8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS04595
gene id: 1408189:CLAC_RS04595
uniprot id: A0A0K2GZK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS01785
gene id: 1408189:CLAC_RS01785
uniprot id: A0A0K2GXZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1408189:CLAC RS01665
gene id: 1408189:CLAC_RS01665
uniprot id: A0A0K2GXY7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1408189:CLAC RS05815
gene id: 1408189:CLAC_RS05815
uniprot id: A0A0K2GZX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1408189:CLAC RS08555
gene id: 1408189:CLAC_RS08555
uniprot id: A0A0K2H1H9
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1408189:CLAC RS00660
gene id: 1408189:CLAC_RS00660
uniprot id: A0A0K2GXH0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1408189:CLAC RS11015
gene id: 1408189:CLAC_RS11015
uniprot id: A0A0K2H364
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1408189:CLAC RS04880
gene id: 1408189:CLAC_RS04880
uniprot id: A0A0K2GZE3
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS06325
gene id: 1408189:CLAC_RS06325
uniprot id: A0A0K2H058
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1408189:CLAC RS00805
gene id: 1408189:CLAC_RS00805
uniprot id: A0A0K2GXV8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1408189:CLAC RS06530
gene id: 1408189:CLAC_RS06530
uniprot id: A0A0K2H091
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS02470
gene id: 1408189:CLAC_RS02470
uniprot id: A0A0K2GYC8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1408189:CLAC RS06740
gene id: 1408189:CLAC_RS06740
uniprot id: A0A0K2H0D5
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS05140
gene id: 1408189:CLAC_RS05140
uniprot id: A0A0K2GZU3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1408189:CLAC RS04790
gene id: 1408189:CLAC_RS04790
uniprot id: A0A0K2GZE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408189:CLAC RS08615
gene id: 1408189:CLAC_RS08615
uniprot id: A0A0K2H183
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1408189:CLAC RS04710
gene id: 1408189:CLAC_RS04710
uniprot id: A0A0K2GZC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1408189:CLAC RS04510
gene id: 1408189:CLAC_RS04510
uniprot id: A0A0K2GZ75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1408189:CLAC RS07395
gene id: 1408189:CLAC_RS07395
uniprot id: A0A0K2H0L1
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1408189:CLAC RS09670
gene id: 1408189:CLAC_RS09670
uniprot id: A0A0K2H1X3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1408189:CLAC RS11800
gene id: 1408189:CLAC_RS11800
uniprot id: A0A0K2H3L6
names: Similarity
messages: Belongs to the fructosamine kinase family.

1408189:CLAC RS00280
gene id: 1408189:CLAC_RS00280
uniprot id: A0A0K2GXN2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1408189:CLAC RS00825
gene id: 1408189:CLAC_RS00825
uniprot id: A0A0K2GYG1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1408189:CLAC RS11155
gene id: 1408189:CLAC_RS11155
uniprot id: A0A0K2H387
names: Similarity
messages: Belongs to the histone deacetylase family.

1408189:CLAC RS02795
gene id: 1408189:CLAC_RS02795
uniprot id: A0A0K2GYI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1408189:CLAC RS03765
gene id: 1408189:CLAC_RS03765
uniprot id: A0A0K2H358
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS11715
gene id: 1408189:CLAC_RS11715
uniprot id: A0A0K2H2W5
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1408189:CLAC RS01380
gene id: 1408189:CLAC_RS01380
uniprot id: A0A0K2GYP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1408189:CLAC RS00495
gene id: 1408189:CLAC_RS00495
uniprot id: A0A0K2GXF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS11930
gene id: 1408189:CLAC_RS11930
uniprot id: A0A0K2H479
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS04905
gene id: 1408189:CLAC_RS04905
uniprot id: A0A0K2GZE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1408189:CLAC RS04430
gene id: 1408189:CLAC_RS04430
uniprot id: A0A0K2H025
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1408189:CLAC RS03065
gene id: 1408189:CLAC_RS03065
uniprot id: A0A0K2GYY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1408189:CLAC RS06135
gene id: 1408189:CLAC_RS06135
uniprot id: A0A0K2H0D7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1408189:CLAC RS03805
gene id: 1408189:CLAC_RS03805
uniprot id: A0A0K2GYX9
names: Similarity
messages: Belongs to the peptidase S33 family.

1408189:CLAC RS06825
gene id: 1408189:CLAC_RS06825
uniprot id: A0A0K2H0F1
names: Similarity
messages: Belongs to the TlyA family.

1408189:CLAC RS03655
gene id: 1408189:CLAC_RS03655
uniprot id: A0A0K2GYV1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1408189:CLAC RS10640
gene id: 1408189:CLAC_RS10640
uniprot id: A0A0K2H215
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1408189:CLAC RS01210
gene id: 1408189:CLAC_RS01210
uniprot id: A0A0K2GY19
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1408189:CLAC RS08105
gene id: 1408189:CLAC_RS08105
uniprot id: A0A0K2H0Z1
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS06270
gene id: 1408189:CLAC_RS06270
uniprot id: A0A0K2H047
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1408189:CLAC RS05730
gene id: 1408189:CLAC_RS05730
uniprot id: A0A0K2H062
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1408189:CLAC RS06080
gene id: 1408189:CLAC_RS06080
uniprot id: A0A0K2H011
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1408189:CLAC RS08400
gene id: 1408189:CLAC_RS08400
uniprot id: A0A0K2H1F8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1408189:CLAC RS00970
gene id: 1408189:CLAC_RS00970
uniprot id: A0A0K2GYH8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1408189:CLAC RS04480
gene id: 1408189:CLAC_RS04480
uniprot id: A0A0K2H035
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1408189:CLAC RS08150
gene id: 1408189:CLAC_RS08150
uniprot id: A0A0K2H114
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1408189:CLAC RS09225
gene id: 1408189:CLAC_RS09225
uniprot id: A0A0K2H1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1408189:CLAC RS05325
gene id: 1408189:CLAC_RS05325
uniprot id: A0A0K2H0M8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1408189:CLAC RS10855
gene id: 1408189:CLAC_RS10855
uniprot id: A0A0K2H2F4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1408189:CLAC RS00740
gene id: 1408189:CLAC_RS00740
uniprot id: A0A0K2GXI2
names: Similarity
messages: Belongs to the CsoR family.

1408189:CLAC RS08855
gene id: 1408189:CLAC_RS08855
uniprot id: A0A0K2H1B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1408189:CLAC RS03770
gene id: 1408189:CLAC_RS03770
uniprot id: A0A0K2GYX1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1408189:CLAC RS07010
gene id: 1408189:CLAC_RS07010
uniprot id: A0A0K2H0S0
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS10655
gene id: 1408189:CLAC_RS10655
uniprot id: A0A0K2H2B9
names: Similarity
messages: Belongs to the peptidase S13 family.

1408189:CLAC RS02695
gene id: 1408189:CLAC_RS02695
uniprot id: A0A0K2GYS6
names: Similarity
messages: Belongs to the HupF/HypC family.

1408189:CLAC RS05980
gene id: 1408189:CLAC_RS05980
uniprot id: A0A0K2GZZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS05935
gene id: 1408189:CLAC_RS05935
uniprot id: A0A0K2H099
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1408189:CLAC RS02765
gene id: 1408189:CLAC_RS02765
uniprot id: A0A0K2GYH9
names: Similarity
messages: Belongs to the thymidylate kinase family.

1408189:CLAC RS11680
gene id: 1408189:CLAC_RS11680
uniprot id: A0A0K2H2M1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1408189:CLAC RS02300
gene id: 1408189:CLAC_RS02300
uniprot id: A0A0K2GYK8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1408189:CLAC RS08605
gene id: 1408189:CLAC_RS08605
uniprot id: A0A0K2H193
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1408189:CLAC RS01415
gene id: 1408189:CLAC_RS01415
uniprot id: A0A0K2GXU0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1408189:CLAC RS07925
gene id: 1408189:CLAC_RS07925
uniprot id: A0A0K2H0X1
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1408189:CLAC RS06145
gene id: 1408189:CLAC_RS06145
uniprot id: A0A0K2H029
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1408189:CLAC RS08390
gene id: 1408189:CLAC_RS08390
uniprot id: A0A0K2H238
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1408189:CLAC RS06000
gene id: 1408189:CLAC_RS06000
uniprot id: A0A0K2H0Y0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1408189:CLAC RS05370
gene id: 1408189:CLAC_RS05370
uniprot id: A0A0K2GZQ0
names: Similarity
messages: Belongs to the PspA/IM30 family.

1408189:CLAC RS07685
gene id: 1408189:CLAC_RS07685
uniprot id: A0A0K2H0Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1408189:CLAC RS06095
gene id: 1408189:CLAC_RS06095
uniprot id: A0A0K2H018
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1408189:CLAC RS10010
gene id: 1408189:CLAC_RS10010
uniprot id: A0A0K2H218
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1408189:CLAC RS05335
gene id: 1408189:CLAC_RS05335
uniprot id: A0A0K2H004
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1408189:CLAC RS07705
gene id: 1408189:CLAC_RS07705
uniprot id: A0A0K2H1N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1408189:CLAC RS00455
gene id: 1408189:CLAC_RS00455
uniprot id: A0A0K2GXD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1408189:CLAC RS01875
gene id: 1408189:CLAC_RS01875
uniprot id: A0A0K2GY16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm

1408189:CLAC RS01635
gene id: 1408189:CLAC_RS01635
uniprot id: A0A0K2GY80
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS10785
gene id: 1408189:CLAC_RS10785
uniprot id: A0A0K2H322
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1408189:CLAC RS01850
gene id: 1408189:CLAC_RS01850
uniprot id: A0A0K2GYB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1408189:CLAC RS02175
gene id: 1408189:CLAC_RS02175
uniprot id: A0A0K2GY72
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1408189:CLAC RS02250
gene id: 1408189:CLAC_RS02250
uniprot id: A0A0K2GYK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1408189:CLAC RS02965
gene id: 1408189:CLAC_RS02965
uniprot id: A0A0K2GYL0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1408189:CLAC RS09785
gene id: 1408189:CLAC_RS09785
uniprot id: A0A0K2H1N2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS10525
gene id: 1408189:CLAC_RS10525
uniprot id: A0A0K2H208
names: Similarity
messages: Belongs to the MmpS family.

1408189:CLAC RS11865
gene id: 1408189:CLAC_RS11865
uniprot id: A0A0K2H3W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1408189:CLAC RS08005
gene id: 1408189:CLAC_RS08005
uniprot id: A0A0K2H0Y7
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS06165
gene id: 1408189:CLAC_RS06165
uniprot id: A0A0K2H043
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1408189:CLAC RS03040
gene id: 1408189:CLAC_RS03040
uniprot id: A0A0K2GYY3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1408189:CLAC RS02780
gene id: 1408189:CLAC_RS02780
uniprot id: A0A0K2H3X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

1408189:CLAC RS05465
gene id: 1408189:CLAC_RS05465
uniprot id: A0A0K2GZR1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1408189:CLAC RS06915
gene id: 1408189:CLAC_RS06915
uniprot id: A0A0K2H0E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1408189:CLAC RS06360
gene id: 1408189:CLAC_RS06360
uniprot id: A0A0K2H063
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1408189:CLAC RS04585
gene id: 1408189:CLAC_RS04585
uniprot id: A0A0K2H064
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1408189:CLAC RS01140
gene id: 1408189:CLAC_RS01140
uniprot id: A0A0K2GXP9
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

1408189:CLAC RS01460
gene id: 1408189:CLAC_RS01460
uniprot id: A0A0K2GYR6
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS04515
gene id: 1408189:CLAC_RS04515
uniprot id: A0A0K2GZI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1408189:CLAC RS03860
gene id: 1408189:CLAC_RS03860
uniprot id: A0A0K2GYY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS11355
gene id: 1408189:CLAC_RS11355
uniprot id: A0A0K2H2D5
names: Similarity
messages: Belongs to the universal stress protein A family.

1408189:CLAC RS11565
gene id: 1408189:CLAC_RS11565
uniprot id: A0A0K2H2K1
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1408189:CLAC RS01255
gene id: 1408189:CLAC_RS01255
uniprot id: A0A0K2GY21
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1408189:CLAC RS08945
gene id: 1408189:CLAC_RS08945
uniprot id: A0A0K2H1E4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1408189:CLAC RS07955
gene id: 1408189:CLAC_RS07955
uniprot id: A0A0K2H0W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1408189:CLAC RS07600
gene id: 1408189:CLAC_RS07600
uniprot id: A0A0K2H1L7
names: Similarity
messages: Belongs to the IMPACT family.

1408189:CLAC RS05890
gene id: 1408189:CLAC_RS05890
uniprot id: A0A0K2GZY7
names: Similarity
messages: Belongs to the peptidase A24 family.

1408189:CLAC RS00220
gene id: 1408189:CLAC_RS00220
uniprot id: A0A0K2GXM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1408189:CLAC RS06020
gene id: 1408189:CLAC_RS06020
uniprot id: A0A0K2H003
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1408189:CLAC RS07740
gene id: 1408189:CLAC_RS07740
uniprot id: A0A0K2H122
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1408189:CLAC RS11145
gene id: 1408189:CLAC_RS11145
uniprot id: A0A0K2H2B1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1408189:CLAC RS05970
gene id: 1408189:CLAC_RS05970
uniprot id: A0A0K2GZZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1408189:CLAC RS01310
gene id: 1408189:CLAC_RS01310
uniprot id: A0A0K2GXS0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1408189:CLAC RS02075
gene id: 1408189:CLAC_RS02075
uniprot id: A0A0K2GYF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1408189:CLAC RS02080
gene id: 1408189:CLAC_RS02080
uniprot id: A0A0K2GY54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1408189:CLAC RS12000
gene id: 1408189:CLAC_RS12000
uniprot id: A0A0K2H304
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1408189:CLAC RS02035
gene id: 1408189:CLAC_RS02035
uniprot id: A0A0K2GY52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1408189:CLAC RS03890
gene id: 1408189:CLAC_RS03890
uniprot id: A0A0K2GYZ1
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS03650
gene id: 1408189:CLAC_RS03650
uniprot id: A0A0K2GZ54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS04980
gene id: 1408189:CLAC_RS04980
uniprot id: A0A0K2H0D9
names: Similarity
messages: Belongs to the acylphosphatase family.

1408189:CLAC RS02615
gene id: 1408189:CLAC_RS02615
uniprot id: A0A0K2GYF2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1408189:CLAC RS00440
gene id: 1408189:CLAC_RS00440
uniprot id: A0A0K2GXD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1408189:CLAC RS00720
gene id: 1408189:CLAC_RS00720
uniprot id: A0A0K2GXU4
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1408189:CLAC RS06755
gene id: 1408189:CLAC_RS06755
uniprot id: A0A0K2H0C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1408189:CLAC RS01235
gene id: 1408189:CLAC_RS01235
uniprot id: A0A0K2GXR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408189:CLAC RS07950
gene id: 1408189:CLAC_RS07950
uniprot id: A0A0K2H0X7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1408189:CLAC RS05265
gene id: 1408189:CLAC_RS05265
uniprot id: A0A0K2GZM4
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS11085
gene id: 1408189:CLAC_RS11085
uniprot id: A0A0K2H377
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

1408189:CLAC RS01955
gene id: 1408189:CLAC_RS01955
uniprot id: A0A0K2GYD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1408189:CLAC RS08090
gene id: 1408189:CLAC_RS08090
uniprot id: A0A0K2H103
names: Similarity
messages: Belongs to the glutamine synthetase family.

1408189:CLAC RS03560
gene id: 1408189:CLAC_RS03560
uniprot id: A0A0K2GYT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1408189:CLAC RS00255
gene id: 1408189:CLAC_RS00255
uniprot id: A0A0K2GXA9
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1408189:CLAC RS04495
gene id: 1408189:CLAC_RS04495
uniprot id: A0A0K2GZ82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1408189:CLAC RS02495
gene id: 1408189:CLAC_RS02495
uniprot id: A0A0K2GZB1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1408189:CLAC RS02450
gene id: 1408189:CLAC_RS02450
uniprot id: A0A0K2GYC7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1408189:CLAC RS08430
gene id: 1408189:CLAC_RS08430
uniprot id: A0A0K2H1G2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1408189:CLAC RS04770
gene id: 1408189:CLAC_RS04770
uniprot id: A0A0K2H0A4
names: Similarity
messages: Belongs to the isochorismate synthase family.

1408189:CLAC RS10945
gene id: 1408189:CLAC_RS10945
uniprot id: A0A0K2H267
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS00470
gene id: 1408189:CLAC_RS00470
uniprot id: A0A0K2GXF0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1408189:CLAC RS00800
gene id: 1408189:CLAC_RS00800
uniprot id: A0A0K2GXJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1408189:CLAC RS04630
gene id: 1408189:CLAC_RS04630
uniprot id: A0A0K2GZA9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1408189:CLAC RS06035
gene id: 1408189:CLAC_RS06035
uniprot id: A0A0K2H0B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1408189:CLAC RS01470
gene id: 1408189:CLAC_RS01470
uniprot id: A0A0K2GY61
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

1408189:CLAC RS06570
gene id: 1408189:CLAC_RS06570
uniprot id: A0A0K2H0K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1408189:CLAC RS02585
gene id: 1408189:CLAC_RS02585
uniprot id: A0A0K2GZC3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1408189:CLAC RS11495
gene id: 1408189:CLAC_RS11495
uniprot id: A0A0K2H2G2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1408189:CLAC RS06060
gene id: 1408189:CLAC_RS06060
uniprot id: A0A0K2H0C3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1408189:CLAC RS01020
gene id: 1408189:CLAC_RS01020
uniprot id: A0A0K2GYI9
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS05320
gene id: 1408189:CLAC_RS05320
uniprot id: A0A0K2GZP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1408189:CLAC RS06560
gene id: 1408189:CLAC_RS06560
uniprot id: A0A0K2H156
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1408189:CLAC RS09905
gene id: 1408189:CLAC_RS09905
uniprot id: A0A0K2H206
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1408189:CLAC RS10395
gene id: 1408189:CLAC_RS10395
uniprot id: A0A0K2H276
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1408189:CLAC RS02885
gene id: 1408189:CLAC_RS02885
uniprot id: A0A0K2GYJ7
names: Similarity
messages: Belongs to the DEAD box helicase family.

1408189:CLAC RS07940
gene id: 1408189:CLAC_RS07940
uniprot id: A0A0K2H0V9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1408189:CLAC RS09405
gene id: 1408189:CLAC_RS09405
uniprot id: A0A0K2H1J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1408189:CLAC RS05430
gene id: 1408189:CLAC_RS05430
uniprot id: A0A0K2H0P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS10835
gene id: 1408189:CLAC_RS10835
uniprot id: A0A0K2H246
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1408189:CLAC RS00320
gene id: 1408189:CLAC_RS00320
uniprot id: A0A0K2GXC7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1408189:CLAC RS06910
gene id: 1408189:CLAC_RS06910
uniprot id: A0A0K2H1B3
names: Similarity
messages: Belongs to the UPF0434 family.

1408189:CLAC RS04990
gene id: 1408189:CLAC_RS04990
uniprot id: A0A0K2GZR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1408189:CLAC RS03660
gene id: 1408189:CLAC_RS03660
uniprot id: A0A0K2GYV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1408189:CLAC RS07475
gene id: 1408189:CLAC_RS07475
uniprot id: A0A0K2H1J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1408189:CLAC RS02520
gene id: 1408189:CLAC_RS02520
uniprot id: A0A0K2H3X6
names: Similarity
messages: Belongs to the intimin/invasin family.

1408189:CLAC RS06730
gene id: 1408189:CLAC_RS06730
uniprot id: A0A0K2H0C0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS02370
gene id: 1408189:CLAC_RS02370
uniprot id: A0A0K2GZ92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS09260
gene id: 1408189:CLAC_RS09260
uniprot id: A0A0K2H1G9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1408189:CLAC RS01475
gene id: 1408189:CLAC_RS01475
uniprot id: A0A0K2GXV0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1408189:CLAC RS10880
gene id: 1408189:CLAC_RS10880
uniprot id: A0A0K2H2F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1408189:CLAC RS00905
gene id: 1408189:CLAC_RS00905
uniprot id: A0A0K2H2T4
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS05855
gene id: 1408189:CLAC_RS05855
uniprot id: A0A0K2GZX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1408189:CLAC RS04455
gene id: 1408189:CLAC_RS04455
uniprot id: A0A0K2H030
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1408189:CLAC RS11745
gene id: 1408189:CLAC_RS11745
uniprot id: A0A0K2H3K7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1408189:CLAC RS06495
gene id: 1408189:CLAC_RS06495
uniprot id: A0A0K2H097
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS01930
gene id: 1408189:CLAC_RS01930
uniprot id: A0A0K2GYC5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1408189:CLAC RS05810
gene id: 1408189:CLAC_RS05810
uniprot id: A0A0K2H077
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1408189:CLAC RS08685
gene id: 1408189:CLAC_RS08685
uniprot id: A0A0K2H277
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1408189:CLAC RS09155
gene id: 1408189:CLAC_RS09155
uniprot id: A0A0K2H1F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1408189:CLAC RS03800
gene id: 1408189:CLAC_RS03800
uniprot id: A0A0K2GYX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1408189:CLAC RS01780
gene id: 1408189:CLAC_RS01780
uniprot id: A0A0K2GYX0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1408189:CLAC RS11150
gene id: 1408189:CLAC_RS11150
uniprot id: A0A0K2H298
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1408189:CLAC RS11460
gene id: 1408189:CLAC_RS11460
uniprot id: A0A0K2H2G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS05235
gene id: 1408189:CLAC_RS05235
uniprot id: A0A0K2GZM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1408189:CLAC RS02415
gene id: 1408189:CLAC_RS02415
uniprot id: A0A0K2GYC2
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS01855
gene id: 1408189:CLAC_RS01855
uniprot id: A0A0K2GY13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1408189:CLAC RS05100
gene id: 1408189:CLAC_RS05100
uniprot id: A0A0K2GZJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1408189:CLAC RS10095
gene id: 1408189:CLAC_RS10095
uniprot id: A0A0K2H232
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1408189:CLAC RS08305
gene id: 1408189:CLAC_RS08305
uniprot id: A0A0K2H135
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1408189:CLAC RS04420
gene id: 1408189:CLAC_RS04420
uniprot id: A0A0K2GZ67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1408189:CLAC RS05120
gene id: 1408189:CLAC_RS05120
uniprot id: A0A0K2GZJ9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS06690
gene id: 1408189:CLAC_RS06690
uniprot id: A0A0K2H0C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS08600
gene id: 1408189:CLAC_RS08600
uniprot id: A0A0K2H1I4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1408189:CLAC RS00920
gene id: 1408189:CLAC_RS00920
uniprot id: A0A0K2GXL0
names: Similarity
messages: Belongs to the catalase family.

1408189:CLAC RS07905
gene id: 1408189:CLAC_RS07905
uniprot id: A0A0K2H0V7
names: Similarity
messages: Belongs to the asparagine synthetase family.

1408189:CLAC RS08730
gene id: 1408189:CLAC_RS08730
uniprot id: A0A0K2H1A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1408189:CLAC RS06720
gene id: 1408189:CLAC_RS06720
uniprot id: A0A0K2H0C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1408189:CLAC RS05900
gene id: 1408189:CLAC_RS05900
uniprot id: A0A0K2H0W3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1408189:CLAC RS08035
gene id: 1408189:CLAC_RS08035
uniprot id: A0A0K2H0Z2
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS09305
gene id: 1408189:CLAC_RS09305
uniprot id: A0A0K2H1T7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1408189:CLAC RS07650
gene id: 1408189:CLAC_RS07650
uniprot id: A0A0K2H0Q6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1408189:CLAC RS04500
gene id: 1408189:CLAC_RS04500
uniprot id: A0A0K2GZ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1408189:CLAC RS11975
gene id: 1408189:CLAC_RS11975
uniprot id: A0A0K2H2Z8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1408189:CLAC RS02245
gene id: 1408189:CLAC_RS02245
uniprot id: A0A0K2GY90
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS01405
gene id: 1408189:CLAC_RS01405
uniprot id: A0A0K2GXT8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1408189:CLAC RS07760
gene id: 1408189:CLAC_RS07760
uniprot id: A0A0K2H0R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1408189:CLAC RS11455
gene id: 1408189:CLAC_RS11455
uniprot id: A0A0K2H2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS06280
gene id: 1408189:CLAC_RS06280
uniprot id: A0A0K2H060
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1408189:CLAC RS10440
gene id: 1408189:CLAC_RS10440
uniprot id: A0A0K2H2V8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1408189:CLAC RS08970
gene id: 1408189:CLAC_RS08970
uniprot id: A0A0K2H1D7
names: Similarity
messages: Belongs to the CsoR family.

1408189:CLAC RS03625
gene id: 1408189:CLAC_RS03625
uniprot id: A0A0K2GYT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1408189:CLAC RS04620
gene id: 1408189:CLAC_RS04620
uniprot id: A0A0K2GZK7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1408189:CLAC RS05500
gene id: 1408189:CLAC_RS05500
uniprot id: A0A0K2GZT0
names: Similarity
messages: Belongs to the UPF0371 family.

1408189:CLAC RS02675
gene id: 1408189:CLAC_RS02675
uniprot id: A0A0K2GYG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1408189:CLAC RS03645
gene id: 1408189:CLAC_RS03645
uniprot id: A0A0K2GYU4
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1408189:CLAC RS02025
gene id: 1408189:CLAC_RS02025
uniprot id: A0A0K2GY48
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1408189:CLAC RS10530
gene id: 1408189:CLAC_RS10530
uniprot id: A0A0K2H1Z7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1408189:CLAC RS03015
gene id: 1408189:CLAC_RS03015
uniprot id: A0A0K2GYX8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1408189:CLAC RS06450
gene id: 1408189:CLAC_RS06450
uniprot id: A0A0K2H078
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1408189:CLAC RS11940
gene id: 1408189:CLAC_RS11940
uniprot id: A0A0K2H2N6
names: Similarity
messages: Belongs to the PspA/IM30 family.

1408189:CLAC RS04190
gene id: 1408189:CLAC_RS04190
uniprot id: A0A0K2GZD5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS03010
gene id: 1408189:CLAC_RS03010
uniprot id: A0A0K2GYL6
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1408189:CLAC RS08870
gene id: 1408189:CLAC_RS08870
uniprot id: A0A0K2H1C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1408189:CLAC RS02050
gene id: 1408189:CLAC_RS02050
uniprot id: A0A0K2GY53
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1408189:CLAC RS02265
gene id: 1408189:CLAC_RS02265
uniprot id: A0A0K2GZ74
names: Similarity
messages: Belongs to the TPP enzyme family.

1408189:CLAC RS08890
gene id: 1408189:CLAC_RS08890
uniprot id: A0A0K2H1D5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS02790
gene id: 1408189:CLAC_RS02790
uniprot id: A0A0K2GYI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1408189:CLAC RS05910
gene id: 1408189:CLAC_RS05910
uniprot id: A0A0K2H094
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1408189:CLAC RS01150
gene id: 1408189:CLAC_RS01150
uniprot id: A0A0K2GXP6
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS07980
gene id: 1408189:CLAC_RS07980
uniprot id: A0A0K2H0X3
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS01340
gene id: 1408189:CLAC_RS01340
uniprot id: A0A0K2GXS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

1408189:CLAC RS03905
gene id: 1408189:CLAC_RS03905
uniprot id: A0A0K2GZU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1408189:CLAC RS08055
gene id: 1408189:CLAC_RS08055
uniprot id: A0A0K2H175
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

1408189:CLAC RS03935
gene id: 1408189:CLAC_RS03935
uniprot id: A0A0K2GZV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1408189:CLAC RS06860
gene id: 1408189:CLAC_RS06860
uniprot id: A0A0K2H0E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1408189:CLAC RS10410
gene id: 1408189:CLAC_RS10410
uniprot id: A0A0K2H1X7
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1408189:CLAC RS08690
gene id: 1408189:CLAC_RS08690
uniprot id: A0A0K2H191
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1408189:CLAC RS04690
gene id: 1408189:CLAC_RS04690
uniprot id: A0A0K2H087
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS01935
gene id: 1408189:CLAC_RS01935
uniprot id: A0A0K2GY28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1408189:CLAC RS07485
gene id: 1408189:CLAC_RS07485
uniprot id: A0A0K2H0X9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1408189:CLAC RS08405
gene id: 1408189:CLAC_RS08405
uniprot id: A0A0K2H164
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1408189:CLAC RS00985
gene id: 1408189:CLAC_RS00985
uniprot id: A0A0K2GXM0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1408189:CLAC RS08650
gene id: 1408189:CLAC_RS08650
uniprot id: A0A0K2H275
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS06510
gene id: 1408189:CLAC_RS06510
uniprot id: A0A0K2H088
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1408189:CLAC RS11010
gene id: 1408189:CLAC_RS11010
uniprot id: A0A0K2H278
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1408189:CLAC RS03855
gene id: 1408189:CLAC_RS03855
uniprot id: A0A0K2GYY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1408189:CLAC RS05660
gene id: 1408189:CLAC_RS05660
uniprot id: A0A0K2H0T0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

1408189:CLAC RS12040
gene id: 1408189:CLAC_RS12040
uniprot id: A0A0K2H2R2
names: Subcellular Location Annotation
messages: Membrane

1408189:CLAC RS09910
gene id: 1408189:CLAC_RS09910
uniprot id: A0A0K2H1S0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1408189:CLAC RS04910
gene id: 1408189:CLAC_RS04910
uniprot id: A0A0K2GZP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1408189:CLAC RS00695
gene id: 1408189:CLAC_RS00695
uniprot id: A0A0K2GXI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1408189:CLAC RS07415
gene id: 1408189:CLAC_RS07415
uniprot id: A0A0K2H0M0
names: Similarity
messages: Belongs to the TrpC family.

1408189:CLAC RS07440
gene id: 1408189:CLAC_RS07440
uniprot id: A0A0K2H0M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1408189:CLAC RS07730
gene id: 1408189:CLAC_RS07730
uniprot id: A0A0K2H1P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1408189:CLAC RS05170
gene id: 1408189:CLAC_RS05170
uniprot id: A0A0K2GZL0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1408189:CLAC RS11285
gene id: 1408189:CLAC_RS11285
uniprot id: A0A0K2H2D8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1408189:CLAC RS04560
gene id: 1408189:CLAC_RS04560
uniprot id: A0A0K2H059
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1408189:CLAC RS09915
gene id: 1408189:CLAC_RS09915
uniprot id: A0A0K2H1Q1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.