1404245:CGLY RS10875
gene id: 1404245:CGLY_RS10875
uniprot id: X5EB17
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1404245:CGLY RS03770
gene id: 1404245:CGLY_RS03770
uniprot id: X5E6Z5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1404245:CGLY RS10160
gene id: 1404245:CGLY_RS10160
uniprot id: X5DT33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS06755
gene id: 1404245:CGLY_RS06755
uniprot id: X5DRB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1404245:CGLY RS07970
gene id: 1404245:CGLY_RS07970
uniprot id: X5DLP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1404245:CGLY RS11350
gene id: 1404245:CGLY_RS11350
uniprot id: X5DTU8
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1404245:CGLY RS04990
gene id: 1404245:CGLY_RS04990
uniprot id: X5DQ69
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1404245:CGLY RS02680
gene id: 1404245:CGLY_RS02680
uniprot id: X5E6B0
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS06105
gene id: 1404245:CGLY_RS06105
uniprot id: X5DKM1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1404245:CGLY RS12660
gene id: 1404245:CGLY_RS12660
uniprot id: X5EEA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1404245:CGLY RS14750
gene id: 1404245:CGLY_RS14750
uniprot id: X5EFJ3
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1404245:CGLY RS10835
gene id: 1404245:CGLY_RS10835
uniprot id: X5DVB5
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1404245:CGLY RS04890
gene id: 1404245:CGLY_RS04890
uniprot id: X5DJZ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1404245:CGLY RS13315
gene id: 1404245:CGLY_RS13315
uniprot id: X5DPF1
names: Similarity
messages: Belongs to the citrate synthase family.

1404245:CGLY RS14725
gene id: 1404245:CGLY_RS14725
uniprot id: X5EFI8
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS04845
gene id: 1404245:CGLY_RS04845
uniprot id: X5DQ49
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1404245:CGLY RS01800
gene id: 1404245:CGLY_RS01800
uniprot id: X5DIF5
names: Similarity
messages: Belongs to the allantoicase family.

1404245:CGLY RS03025
gene id: 1404245:CGLY_RS03025
uniprot id: X5E6I1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1404245:CGLY RS09160
gene id: 1404245:CGLY_RS09160
uniprot id: X5ECE1
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS07105
gene id: 1404245:CGLY_RS07105
uniprot id: X5DRF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1404245:CGLY RS08105
gene id: 1404245:CGLY_RS08105
uniprot id: X5E9F8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

1404245:CGLY RS12305
gene id: 1404245:CGLY_RS12305
uniprot id: X5DWA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1404245:CGLY RS16225
gene id: 1404245:CGLY_RS16225
uniprot id: X5EGC2
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS03530
gene id: 1404245:CGLY_RS03530
uniprot id: X5DR56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1404245:CGLY RS06270
gene id: 1404245:CGLY_RS06270
uniprot id: X5EAM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1404245:CGLY RS13875
gene id: 1404245:CGLY_RS13875
uniprot id: X5EF05
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1404245:CGLY RS08395
gene id: 1404245:CGLY_RS08395
uniprot id: X5DTV9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS09260
gene id: 1404245:CGLY_RS09260
uniprot id: X5ECI5
names: Similarity
messages: Belongs to the TlyA family.

1404245:CGLY RS06745
gene id: 1404245:CGLY_RS06745
uniprot id: X5DT21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1404245:CGLY RS16075
gene id: 1404245:CGLY_RS16075
uniprot id: X5DYC8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1404245:CGLY RS02305
gene id: 1404245:CGLY_RS02305
uniprot id: X5E8B7
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS03925
gene id: 1404245:CGLY_RS03925
uniprot id: X5E9A1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS17290
gene id: 1404245:CGLY_RS17290
uniprot id: X5EGD6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1404245:CGLY RS08285
gene id: 1404245:CGLY_RS08285
uniprot id: X5DS26
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1404245:CGLY RS07500
gene id: 1404245:CGLY_RS07500
uniprot id: X5DRL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1404245:CGLY RS12260
gene id: 1404245:CGLY_RS12260
uniprot id: X5DNX7
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS09795
gene id: 1404245:CGLY_RS09795
uniprot id: X5DMP3
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS12485
gene id: 1404245:CGLY_RS12485
uniprot id: X5EE75
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1404245:CGLY RS13515
gene id: 1404245:CGLY_RS13515
uniprot id: X5DPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1404245:CGLY RS15860
gene id: 1404245:CGLY_RS15860
uniprot id: X5DW73
names: Similarity
messages: Belongs to the CFA/CMAS family.

1404245:CGLY RS06015
gene id: 1404245:CGLY_RS06015
uniprot id: X5E875
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS10685
gene id: 1404245:CGLY_RS10685
uniprot id: X5DV84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1404245:CGLY RS06975
gene id: 1404245:CGLY_RS06975
uniprot id: X5DL66
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS04995
gene id: 1404245:CGLY_RS04995
uniprot id: X5E7N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1404245:CGLY RS11545
gene id: 1404245:CGLY_RS11545
uniprot id: X5DNK6
names: Similarity
messages: Belongs to the LOG family.

1404245:CGLY RS00025
gene id: 1404245:CGLY_RS00025
uniprot id: X5E4Q4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1404245:CGLY RS13435
gene id: 1404245:CGLY_RS13435
uniprot id: X5DWU4
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS12985
gene id: 1404245:CGLY_RS12985
uniprot id: X5EC88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1404245:CGLY RS01710
gene id: 1404245:CGLY_RS01710
uniprot id: X5E5U3
names: Similarity
messages: Belongs to the sulfatase family.

1404245:CGLY RS07645
gene id: 1404245:CGLY_RS07645
uniprot id: X5DLI1
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS16130
gene id: 1404245:CGLY_RS16130
uniprot id: X5DQY7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1404245:CGLY RS04125
gene id: 1404245:CGLY_RS04125
uniprot id: X5E782
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS14105
gene id: 1404245:CGLY_RS14105
uniprot id: X5ECX6
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS13830
gene id: 1404245:CGLY_RS13830
uniprot id: X5DX14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1404245:CGLY RS14810
gene id: 1404245:CGLY_RS14810
uniprot id: X5DQ75
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1404245:CGLY RS10725
gene id: 1404245:CGLY_RS10725
uniprot id: X5EAY0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1404245:CGLY RS01405
gene id: 1404245:CGLY_RS01405
uniprot id: X5DI57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS10555
gene id: 1404245:CGLY_RS10555
uniprot id: X5ED28
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1404245:CGLY RS16370
gene id: 1404245:CGLY_RS16370
uniprot id: X5DR40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS01530
gene id: 1404245:CGLY_RS01530
uniprot id: X5DNA1
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS01295
gene id: 1404245:CGLY_RS01295
uniprot id: X5E5G2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1404245:CGLY RS10115
gene id: 1404245:CGLY_RS10115
uniprot id: X5DT20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1404245:CGLY RS07530
gene id: 1404245:CGLY_RS07530
uniprot id: X5E933
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS15855
gene id: 1404245:CGLY_RS15855
uniprot id: X5DQS9
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS03565
gene id: 1404245:CGLY_RS03565
uniprot id: X5DPE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1404245:CGLY RS06875
gene id: 1404245:CGLY_RS06875
uniprot id: X5DL57
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS03295
gene id: 1404245:CGLY_RS03295
uniprot id: X5DP89
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1404245:CGLY RS08190
gene id: 1404245:CGLY_RS08190
uniprot id: X5E9G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1404245:CGLY RS04040
gene id: 1404245:CGLY_RS04040
uniprot id: X5DJI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1404245:CGLY RS16105
gene id: 1404245:CGLY_RS16105
uniprot id: X5DQY1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS01475
gene id: 1404245:CGLY_RS01475
uniprot id: X5DQ12
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS10195
gene id: 1404245:CGLY_RS10195
uniprot id: X5EAP0
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1404245:CGLY RS15540
gene id: 1404245:CGLY_RS15540
uniprot id: X5DW07
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS06265
gene id: 1404245:CGLY_RS06265
uniprot id: X5E8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1404245:CGLY RS02105
gene id: 1404245:CGLY_RS02105
uniprot id: X5E605
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1404245:CGLY RS12725
gene id: 1404245:CGLY_RS12725
uniprot id: X5DUJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1404245:CGLY RS10315
gene id: 1404245:CGLY_RS10315
uniprot id: X5DV16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1404245:CGLY RS01565
gene id: 1404245:CGLY_RS01565
uniprot id: X5E7X5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1404245:CGLY RS11500
gene id: 1404245:CGLY_RS11500
uniprot id: X5DTY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1404245:CGLY RS01870
gene id: 1404245:CGLY_RS01870
uniprot id: X5DIG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1404245:CGLY RS07295
gene id: 1404245:CGLY_RS07295
uniprot id: X5DRI1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1404245:CGLY RS09250
gene id: 1404245:CGLY_RS09250
uniprot id: X5DSN6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1404245:CGLY RS12280
gene id: 1404245:CGLY_RS12280
uniprot id: X5DW99
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1404245:CGLY RS09955
gene id: 1404245:CGLY_RS09955
uniprot id: X5ECU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1404245:CGLY RS16100
gene id: 1404245:CGLY_RS16100
uniprot id: X5DYD0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1404245:CGLY RS03575
gene id: 1404245:CGLY_RS03575
uniprot id: X5E921
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1404245:CGLY RS14845
gene id: 1404245:CGLY_RS14845
uniprot id: X5EDB7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1404245:CGLY RS09610
gene id: 1404245:CGLY_RS09610
uniprot id: X5ECN7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1404245:CGLY RS09075
gene id: 1404245:CGLY_RS09075
uniprot id: X5EA21
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1404245:CGLY RS03145
gene id: 1404245:CGLY_RS03145
uniprot id: X5DP56
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1404245:CGLY RS07600
gene id: 1404245:CGLY_RS07600
uniprot id: X5DRN7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1404245:CGLY RS08075
gene id: 1404245:CGLY_RS08075
uniprot id: X5DRY8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1404245:CGLY RS15000
gene id: 1404245:CGLY_RS15000
uniprot id: X5EFN5
names: Similarity
messages: Belongs to the DapA family.

1404245:CGLY RS02685
gene id: 1404245:CGLY_RS02685
uniprot id: X5E8I7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1404245:CGLY RS09235
gene id: 1404245:CGLY_RS09235
uniprot id: X5ECH4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS12015
gene id: 1404245:CGLY_RS12015
uniprot id: X5DU88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS00860
gene id: 1404245:CGLY_RS00860
uniprot id: X5DHU9
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS09910
gene id: 1404245:CGLY_RS09910
uniprot id: X5DUT9
names: Similarity
messages: Belongs to the peptidase C40 family.

1404245:CGLY RS13820
gene id: 1404245:CGLY_RS13820
uniprot id: X5ECR0
names: Similarity
messages: Belongs to the peptidase S13 family.

1404245:CGLY RS14940
gene id: 1404245:CGLY_RS14940
uniprot id: X5DQ94
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1404245:CGLY RS09555
gene id: 1404245:CGLY_RS09555
uniprot id: X5EAC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1404245:CGLY RS11175
gene id: 1404245:CGLY_RS11175
uniprot id: X5DTR0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1404245:CGLY RS07275
gene id: 1404245:CGLY_RS07275
uniprot id: X5E8Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS09715
gene id: 1404245:CGLY_RS09715
uniprot id: X5DUQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1404245:CGLY RS10535
gene id: 1404245:CGLY_RS10535
uniprot id: X5DV58
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS07300
gene id: 1404245:CGLY_RS07300
uniprot id: X5E8Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1404245:CGLY RS10980
gene id: 1404245:CGLY_RS10980
uniprot id: X5EDC4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1404245:CGLY RS11710
gene id: 1404245:CGLY_RS11710
uniprot id: X5EDU5
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1404245:CGLY RS03010
gene id: 1404245:CGLY_RS03010
uniprot id: X5DQW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1404245:CGLY RS09930
gene id: 1404245:CGLY_RS09930
uniprot id: X5ECT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1404245:CGLY RS00390
gene id: 1404245:CGLY_RS00390
uniprot id: X5DHL2
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS04655
gene id: 1404245:CGLY_RS04655
uniprot id: X5DRV2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1404245:CGLY RS11555
gene id: 1404245:CGLY_RS11555
uniprot id: X5EBH6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1404245:CGLY RS14710
gene id: 1404245:CGLY_RS14710
uniprot id: X5DQ63
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1404245:CGLY RS06300
gene id: 1404245:CGLY_RS06300
uniprot id: X5DSP8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1404245:CGLY RS06870
gene id: 1404245:CGLY_RS06870
uniprot id: X5DT44
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS12885
gene id: 1404245:CGLY_RS12885
uniprot id: X5EC69
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1404245:CGLY RS10550
gene id: 1404245:CGLY_RS10550
uniprot id: X5EAU9
names: Similarity
messages: Belongs to the AHA1 family.

1404245:CGLY RS01775
gene id: 1404245:CGLY_RS01775
uniprot id: X5DIF3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1404245:CGLY RS08250
gene id: 1404245:CGLY_RS08250
uniprot id: X5DTT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1404245:CGLY RS12710
gene id: 1404245:CGLY_RS12710
uniprot id: X5EEB4
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1404245:CGLY RS14540
gene id: 1404245:CGLY_RS14540
uniprot id: X5ED70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1404245:CGLY RS11605
gene id: 1404245:CGLY_RS11605
uniprot id: X5EBI6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1404245:CGLY RS09835
gene id: 1404245:CGLY_RS09835
uniprot id: X5ECS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1404245:CGLY RS04265
gene id: 1404245:CGLY_RS04265
uniprot id: X5DJP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1404245:CGLY RS13625
gene id: 1404245:CGLY_RS13625
uniprot id: X5DV13
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS15265
gene id: 1404245:CGLY_RS15265
uniprot id: X5DVU9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1404245:CGLY RS09085
gene id: 1404245:CGLY_RS09085
uniprot id: X5DU98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1404245:CGLY RS01350
gene id: 1404245:CGLY_RS01350
uniprot id: X5E7R9
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS02125
gene id: 1404245:CGLY_RS02125
uniprot id: X5DNL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS00890
gene id: 1404245:CGLY_RS00890
uniprot id: X5DMV2
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS08795
gene id: 1404245:CGLY_RS08795
uniprot id: X5DU28
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1404245:CGLY RS08370
gene id: 1404245:CGLY_RS08370
uniprot id: X5DTV5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1404245:CGLY RS06605
gene id: 1404245:CGLY_RS06605
uniprot id: X5E8M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1404245:CGLY RS04270
gene id: 1404245:CGLY_RS04270
uniprot id: X5DPW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS10525
gene id: 1404245:CGLY_RS10525
uniprot id: X5EAU5
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS15060
gene id: 1404245:CGLY_RS15060
uniprot id: X5DQB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1404245:CGLY RS09560
gene id: 1404245:CGLY_RS09560
uniprot id: X5ECM9
names: Similarity
messages: Belongs to the TrpC family.

1404245:CGLY RS07205
gene id: 1404245:CGLY_RS07205
uniprot id: X5EB83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1404245:CGLY RS00560
gene id: 1404245:CGLY_RS00560
uniprot id: X5DPH0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1404245:CGLY RS04925
gene id: 1404245:CGLY_RS04925
uniprot id: X5E9V4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1404245:CGLY RS13360
gene id: 1404245:CGLY_RS13360
uniprot id: X5DWT1
names: Similarity
messages: Belongs to the GARS family.

1404245:CGLY RS06570
gene id: 1404245:CGLY_RS06570
uniprot id: X5DSW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1404245:CGLY RS12640
gene id: 1404245:CGLY_RS12640
uniprot id: X5DWG1
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

1404245:CGLY RS07935
gene id: 1404245:CGLY_RS07935
uniprot id: X5EBK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1404245:CGLY RS11435
gene id: 1404245:CGLY_RS11435
uniprot id: X5EDN6
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1404245:CGLY RS03460
gene id: 1404245:CGLY_RS03460
uniprot id: X5DJ74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1404245:CGLY RS14210
gene id: 1404245:CGLY_RS14210
uniprot id: X5EF80
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1404245:CGLY RS10310
gene id: 1404245:CGLY_RS10310
uniprot id: X5ECZ3
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS09985
gene id: 1404245:CGLY_RS09985
uniprot id: X5DUV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1404245:CGLY RS13565
gene id: 1404245:CGLY_RS13565
uniprot id: X5DPJ0
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1404245:CGLY RS00255
gene id: 1404245:CGLY_RS00255
uniprot id: X5E749
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1404245:CGLY RS07900
gene id: 1404245:CGLY_RS07900
uniprot id: X5DRV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS04225
gene id: 1404245:CGLY_RS04225
uniprot id: X5E7B2
names: Function
names: Subunit
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1404245:CGLY RS08255
gene id: 1404245:CGLY_RS08255
uniprot id: X5DLT7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1404245:CGLY RS09915
gene id: 1404245:CGLY_RS09915
uniprot id: X5DMR3
names: Similarity
messages: Belongs to the peptidase C40 family.

1404245:CGLY RS03765
gene id: 1404245:CGLY_RS03765
uniprot id: X5DPI8
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS03905
gene id: 1404245:CGLY_RS03905
uniprot id: X5DRD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1404245:CGLY RS09540
gene id: 1404245:CGLY_RS09540
uniprot id: X5DUL9
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1404245:CGLY RS11940
gene id: 1404245:CGLY_RS11940
uniprot id: X5DU77
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1404245:CGLY RS13890
gene id: 1404245:CGLY_RS13890
uniprot id: X5DV66
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS10930
gene id: 1404245:CGLY_RS10930
uniprot id: X5EDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS12495
gene id: 1404245:CGLY_RS12495
uniprot id: X5DP14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1404245:CGLY RS12970
gene id: 1404245:CGLY_RS12970
uniprot id: X5DWL8
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1404245:CGLY RS06730
gene id: 1404245:CGLY_RS06730
uniprot id: X5DRB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1404245:CGLY RS14995
gene id: 1404245:CGLY_RS14995
uniprot id: X5EDE2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1404245:CGLY RS02095
gene id: 1404245:CGLY_RS02095
uniprot id: X5DIJ8
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1404245:CGLY RS14445
gene id: 1404245:CGLY_RS14445
uniprot id: X5DXK5
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS09775
gene id: 1404245:CGLY_RS09775
uniprot id: X5DSW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1404245:CGLY RS10335
gene id: 1404245:CGLY_RS10335
uniprot id: X5ECZ6
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS07715
gene id: 1404245:CGLY_RS07715
uniprot id: X5DTI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1404245:CGLY RS15115
gene id: 1404245:CGLY_RS15115
uniprot id: X5DVS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cell inner membrane
messages: Membrane

1404245:CGLY RS12525
gene id: 1404245:CGLY_RS12525
uniprot id: X5DUF6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1404245:CGLY RS15485
gene id: 1404245:CGLY_RS15485
uniprot id: X5DQK7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS10775
gene id: 1404245:CGLY_RS10775
uniprot id: X5EAZ3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1404245:CGLY RS09655
gene id: 1404245:CGLY_RS09655
uniprot id: X5EAE1
names: Similarity
messages: Belongs to the HSP15 family.

1404245:CGLY RS09615
gene id: 1404245:CGLY_RS09615
uniprot id: X5DUN1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1404245:CGLY RS11470
gene id: 1404245:CGLY_RS11470
uniprot id: X5DNJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1404245:CGLY RS02575
gene id: 1404245:CGLY_RS02575
uniprot id: X5DNS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1404245:CGLY RS14550
gene id: 1404245:CGLY_RS14550
uniprot id: X5DXM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1404245:CGLY RS07285
gene id: 1404245:CGLY_RS07285
uniprot id: X5DTB4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1404245:CGLY RS03580
gene id: 1404245:CGLY_RS03580
uniprot id: X5DR64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1404245:CGLY RS06190
gene id: 1404245:CGLY_RS06190
uniprot id: X5E8B6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS08510
gene id: 1404245:CGLY_RS08510
uniprot id: X5E9N3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1404245:CGLY RS08425
gene id: 1404245:CGLY_RS08425
uniprot id: X5DLX1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS06050
gene id: 1404245:CGLY_RS06050
uniprot id: X5DSK0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1404245:CGLY RS14765
gene id: 1404245:CGLY_RS14765
uniprot id: X5DVL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

1404245:CGLY RS00160
gene id: 1404245:CGLY_RS00160
uniprot id: X5DP99
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1404245:CGLY RS06555
gene id: 1404245:CGLY_RS06555
uniprot id: X5DR60
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1404245:CGLY RS03555
gene id: 1404245:CGLY_RS03555
uniprot id: X5DR61
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1404245:CGLY RS07025
gene id: 1404245:CGLY_RS07025
uniprot id: X5DL72
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS05420
gene id: 1404245:CGLY_RS05420
uniprot id: X5EA45
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS02015
gene id: 1404245:CGLY_RS02015
uniprot id: X5DQC7
names: Similarity
messages: Belongs to the peptidase M20A family.

1404245:CGLY RS07850
gene id: 1404245:CGLY_RS07850
uniprot id: X5DRU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1404245:CGLY RS04030
gene id: 1404245:CGLY_RS04030
uniprot id: X5E9C8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1404245:CGLY RS13790
gene id: 1404245:CGLY_RS13790
uniprot id: X5DV47
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1404245:CGLY RS15590
gene id: 1404245:CGLY_RS15590
uniprot id: X5EFX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS09025
gene id: 1404245:CGLY_RS09025
uniprot id: X5EA09
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1404245:CGLY RS00435
gene id: 1404245:CGLY_RS00435
uniprot id: X5DPE8
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS07485
gene id: 1404245:CGLY_RS07485
uniprot id: X5EBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1404245:CGLY RS03200
gene id: 1404245:CGLY_RS03200
uniprot id: X5E6L8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1404245:CGLY RS15090
gene id: 1404245:CGLY_RS15090
uniprot id: X5DVR6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1404245:CGLY RS08530
gene id: 1404245:CGLY_RS08530
uniprot id: X5DS72
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1404245:CGLY RS04870
gene id: 1404245:CGLY_RS04870
uniprot id: X5DQ52
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS01725
gene id: 1404245:CGLY_RS01725
uniprot id: X5DIE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS16110
gene id: 1404245:CGLY_RS16110
uniprot id: X5DWC9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1404245:CGLY RS02485
gene id: 1404245:CGLY_RS02485
uniprot id: X5E8E6
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

1404245:CGLY RS05765
gene id: 1404245:CGLY_RS05765
uniprot id: X5DQN6
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1404245:CGLY RS03640
gene id: 1404245:CGLY_RS03640
uniprot id: X5DPG1
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1404245:CGLY RS10585
gene id: 1404245:CGLY_RS10585
uniprot id: X5DV68
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1404245:CGLY RS03550
gene id: 1404245:CGLY_RS03550
uniprot id: X5E915
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1404245:CGLY RS15305
gene id: 1404245:CGLY_RS15305
uniprot id: X5DXZ6
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS11675
gene id: 1404245:CGLY_RS11675
uniprot id: X5DU18
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS08380
gene id: 1404245:CGLY_RS08380
uniprot id: X5DS46
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1404245:CGLY RS16640
gene id: 1404245:CGLY_RS16640
uniprot id: X5DJ85
names: Similarity
messages: Belongs to the asp23 family.

1404245:CGLY RS13175
gene id: 1404245:CGLY_RS13175
uniprot id: X5ECB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1404245:CGLY RS15310
gene id: 1404245:CGLY_RS15310
uniprot id: X5DQH1
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS05555
gene id: 1404245:CGLY_RS05555
uniprot id: X5DKB6
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS04885
gene id: 1404245:CGLY_RS04885
uniprot id: X5DRZ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1404245:CGLY RS07280
gene id: 1404245:CGLY_RS07280
uniprot id: X5EB97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1404245:CGLY RS03635
gene id: 1404245:CGLY_RS03635
uniprot id: X5DJB0
names: Similarity
messages: Belongs to the DszC flavin monooxygenase family.

1404245:CGLY RS15130
gene id: 1404245:CGLY_RS15130
uniprot id: X5DXW2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1404245:CGLY RS04965
gene id: 1404245:CGLY_RS04965
uniprot id: X5DQ65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1404245:CGLY RS11925
gene id: 1404245:CGLY_RS11925
uniprot id: X5DU74
names: Similarity
messages: Belongs to the TfdA dioxygenase family.
messages: Belongs to the clavaminate synthase family.

1404245:CGLY RS04800
gene id: 1404245:CGLY_RS04800
uniprot id: X5E7J8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1404245:CGLY RS07995
gene id: 1404245:CGLY_RS07995
uniprot id: X5DLP6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1404245:CGLY RS12875
gene id: 1404245:CGLY_RS12875
uniprot id: X5DP82
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS12955
gene id: 1404245:CGLY_RS12955
uniprot id: X5DUN7
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1404245:CGLY RS00945
gene id: 1404245:CGLY_RS00945
uniprot id: X5E588
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1404245:CGLY RS06810
gene id: 1404245:CGLY_RS06810
uniprot id: X5E8R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS08850
gene id: 1404245:CGLY_RS08850
uniprot id: X5DM56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS04920
gene id: 1404245:CGLY_RS04920
uniprot id: X5E7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1404245:CGLY RS08035
gene id: 1404245:CGLY_RS08035
uniprot id: X5EBM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1404245:CGLY RS10855
gene id: 1404245:CGLY_RS10855
uniprot id: X5ED92
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1404245:CGLY RS00975
gene id: 1404245:CGLY_RS00975
uniprot id: X5E7I3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1404245:CGLY RS08280
gene id: 1404245:CGLY_RS08280
uniprot id: X5DLU3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1404245:CGLY RS06690
gene id: 1404245:CGLY_RS06690
uniprot id: X5EAZ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS14040
gene id: 1404245:CGLY_RS14040
uniprot id: X5DX75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1404245:CGLY RS01790
gene id: 1404245:CGLY_RS01790
uniprot id: X5E839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1404245:CGLY RS12735
gene id: 1404245:CGLY_RS12735
uniprot id: X5EEB9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1404245:CGLY RS03475
gene id: 1404245:CGLY_RS03475
uniprot id: X5E8Z9
names: Similarity
messages: Belongs to the isochorismate synthase family.

1404245:CGLY RS05445
gene id: 1404245:CGLY_RS05445
uniprot id: X5EA49
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS11290
gene id: 1404245:CGLY_RS11290
uniprot id: X5DVK2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

1404245:CGLY RS07960
gene id: 1404245:CGLY_RS07960
uniprot id: X5EBL1
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1404245:CGLY RS07895
gene id: 1404245:CGLY_RS07895
uniprot id: X5DLM7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1404245:CGLY RS13415
gene id: 1404245:CGLY_RS13415
uniprot id: X5DPG8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1404245:CGLY RS04220
gene id: 1404245:CGLY_RS04220
uniprot id: X5DPW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1404245:CGLY RS13990
gene id: 1404245:CGLY_RS13990
uniprot id: X5DV86
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS14255
gene id: 1404245:CGLY_RS14255
uniprot id: X5ED09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1404245:CGLY RS13815
gene id: 1404245:CGLY_RS13815
uniprot id: X5DV52
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1404245:CGLY RS16240
gene id: 1404245:CGLY_RS16240
uniprot id: X5DWF7
names: Similarity
messages: Belongs to the thioredoxin family.

1404245:CGLY RS15530
gene id: 1404245:CGLY_RS15530
uniprot id: X5DY37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1404245:CGLY RS09830
gene id: 1404245:CGLY_RS09830
uniprot id: X5EAG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1404245:CGLY RS04415
gene id: 1404245:CGLY_RS04415
uniprot id: X5DPY7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS09480
gene id: 1404245:CGLY_RS09480
uniprot id: X5ECL8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1404245:CGLY RS04875
gene id: 1404245:CGLY_RS04875
uniprot id: X5E7L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1404245:CGLY RS06185
gene id: 1404245:CGLY_RS06185
uniprot id: X5DQY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1404245:CGLY RS04185
gene id: 1404245:CGLY_RS04185
uniprot id: X5DRL7
names: Similarity
messages: Belongs to the peptidase S9C family.

1404245:CGLY RS10620
gene id: 1404245:CGLY_RS10620
uniprot id: X5DTD7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1404245:CGLY RS11615
gene id: 1404245:CGLY_RS11615
uniprot id: X5DVV3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1404245:CGLY RS13255
gene id: 1404245:CGLY_RS13255
uniprot id: X5EEJ7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1404245:CGLY RS09060
gene id: 1404245:CGLY_RS09060
uniprot id: X5DU89
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1404245:CGLY RS08445
gene id: 1404245:CGLY_RS08445
uniprot id: X5DTW8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1404245:CGLY RS09800
gene id: 1404245:CGLY_RS09800
uniprot id: X5DSW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1404245:CGLY RS13250
gene id: 1404245:CGLY_RS13250
uniprot id: X5ECC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1404245:CGLY RS10075
gene id: 1404245:CGLY_RS10075
uniprot id: X5ECV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS03230
gene id: 1404245:CGLY_RS03230
uniprot id: X5E8U3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1404245:CGLY RS12170
gene id: 1404245:CGLY_RS12170
uniprot id: X5EE28
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1404245:CGLY RS02675
gene id: 1404245:CGLY_RS02675
uniprot id: X5DNU3
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS05710
gene id: 1404245:CGLY_RS05710
uniprot id: X5DKE4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1404245:CGLY RS03630
gene id: 1404245:CGLY_RS03630
uniprot id: X5DR75
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1404245:CGLY RS00265
gene id: 1404245:CGLY_RS00265
uniprot id: X5DHJ0
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS09790
gene id: 1404245:CGLY_RS09790
uniprot id: X5DUR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS06160
gene id: 1404245:CGLY_RS06160
uniprot id: X5DQX8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1404245:CGLY RS03410
gene id: 1404245:CGLY_RS03410
uniprot id: X5DJ64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1404245:CGLY RS05820
gene id: 1404245:CGLY_RS05820
uniprot id: X5E833
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1404245:CGLY RS08585
gene id: 1404245:CGLY_RS08585
uniprot id: X5E9Q3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1404245:CGLY RS02560
gene id: 1404245:CGLY_RS02560
uniprot id: X5E8G2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1404245:CGLY RS01020
gene id: 1404245:CGLY_RS01020
uniprot id: X5E5A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1404245:CGLY RS00855
gene id: 1404245:CGLY_RS00855
uniprot id: X5DPN1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1404245:CGLY RS09225
gene id: 1404245:CGLY_RS09225
uniprot id: X5DSM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1404245:CGLY RS08595
gene id: 1404245:CGLY_RS08595
uniprot id: X5DTZ5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1404245:CGLY RS14785
gene id: 1404245:CGLY_RS14785
uniprot id: X5DQ73
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1404245:CGLY RS10210
gene id: 1404245:CGLY_RS10210
uniprot id: X5DMW1
names: Similarity
messages: Belongs to the AHA1 family.

1404245:CGLY RS01720
gene id: 1404245:CGLY_RS01720
uniprot id: X5DQ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS11715
gene id: 1404245:CGLY_RS11715
uniprot id: X5DVY4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1404245:CGLY RS01695
gene id: 1404245:CGLY_RS01695
uniprot id: X5DQ79
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

1404245:CGLY RS13290
gene id: 1404245:CGLY_RS13290
uniprot id: X5DPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS03815
gene id: 1404245:CGLY_RS03815
uniprot id: X5DPJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1404245:CGLY RS13620
gene id: 1404245:CGLY_RS13620
uniprot id: X5DPJ8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1404245:CGLY RS09810
gene id: 1404245:CGLY_RS09810
uniprot id: X5ECR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1404245:CGLY RS06250
gene id: 1404245:CGLY_RS06250
uniprot id: X5DSN5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1404245:CGLY RS00895
gene id: 1404245:CGLY_RS00895
uniprot id: X5E578
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS07445
gene id: 1404245:CGLY_RS07445
uniprot id: X5DLE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1404245:CGLY RS04080
gene id: 1404245:CGLY_RS04080
uniprot id: X5E9E0
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1404245:CGLY RS09995
gene id: 1404245:CGLY_RS09995
uniprot id: X5DSZ5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1404245:CGLY RS11950
gene id: 1404245:CGLY_RS11950
uniprot id: X5EE03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1404245:CGLY RS14850
gene id: 1404245:CGLY_RS14850
uniprot id: X5EFK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

1404245:CGLY RS03205
gene id: 1404245:CGLY_RS03205
uniprot id: X5E8T6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1404245:CGLY RS09255
gene id: 1404245:CGLY_RS09255
uniprot id: X5EA78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS13090
gene id: 1404245:CGLY_RS13090
uniprot id: X5EEH1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1404245:CGLY RS11050
gene id: 1404245:CGLY_RS11050
uniprot id: X5DTN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS02425
gene id: 1404245:CGLY_RS02425
uniprot id: X5E657
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1404245:CGLY RS02440
gene id: 1404245:CGLY_RS02440
uniprot id: X5DIQ1
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

1404245:CGLY RS07055
gene id: 1404245:CGLY_RS07055
uniprot id: X5DRF2
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS10045
gene id: 1404245:CGLY_RS10045
uniprot id: X5DT05
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS01065
gene id: 1404245:CGLY_RS01065
uniprot id: X5DMZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1404245:CGLY RS07455
gene id: 1404245:CGLY_RS07455
uniprot id: X5E923
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1404245:CGLY RS10130
gene id: 1404245:CGLY_RS10130
uniprot id: X5DUY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1404245:CGLY RS09365
gene id: 1404245:CGLY_RS09365
uniprot id: X5DSQ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1404245:CGLY RS04880
gene id: 1404245:CGLY_RS04880
uniprot id: X5E9U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1404245:CGLY RS03745
gene id: 1404245:CGLY_RS03745
uniprot id: X5E6Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1404245:CGLY RS15525
gene id: 1404245:CGLY_RS15525
uniprot id: X5EFW9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1404245:CGLY RS08325
gene id: 1404245:CGLY_RS08325
uniprot id: X5DLV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1404245:CGLY RS12460
gene id: 1404245:CGLY_RS12460
uniprot id: X5EE71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1404245:CGLY RS13675
gene id: 1404245:CGLY_RS13675
uniprot id: X5EEV2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1404245:CGLY RS03845
gene id: 1404245:CGLY_RS03845
uniprot id: X5E715
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1404245:CGLY RS00630
gene id: 1404245:CGLY_RS00630
uniprot id: X5E7A9
names: Similarity
messages: Belongs to the pirin family.

1404245:CGLY RS08320
gene id: 1404245:CGLY_RS08320
uniprot id: X5DTU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1404245:CGLY RS00715
gene id: 1404245:CGLY_RS00715
uniprot id: X5DMS0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1404245:CGLY RS03560
gene id: 1404245:CGLY_RS03560
uniprot id: X5DJ96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1404245:CGLY RS03715
gene id: 1404245:CGLY_RS03715
uniprot id: X5DPH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1404245:CGLY RS08355
gene id: 1404245:CGLY_RS08355
uniprot id: X5DS42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1404245:CGLY RS10025
gene id: 1404245:CGLY_RS10025
uniprot id: X5EAK4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1404245:CGLY RS08315
gene id: 1404245:CGLY_RS08315
uniprot id: X5EBT4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1404245:CGLY RS13680
gene id: 1404245:CGLY_RS13680
uniprot id: X5DWY2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1404245:CGLY RS03985
gene id: 1404245:CGLY_RS03985
uniprot id: X5DJH9
names: Similarity
messages: Belongs to the WXG100 family.

1404245:CGLY RS11265
gene id: 1404245:CGLY_RS11265
uniprot id: X5DVJ7
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS09140
gene id: 1404245:CGLY_RS09140
uniprot id: X5DMC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1404245:CGLY RS10320
gene id: 1404245:CGLY_RS10320
uniprot id: X5DMX7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1404245:CGLY RS11115
gene id: 1404245:CGLY_RS11115
uniprot id: X5DVG5
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1404245:CGLY RS09550
gene id: 1404245:CGLY_RS09550
uniprot id: X5DSS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1404245:CGLY RS00950
gene id: 1404245:CGLY_RS00950
uniprot id: X5E7H7
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS13060
gene id: 1404245:CGLY_RS13060
uniprot id: X5DWN0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1404245:CGLY RS04950
gene id: 1404245:CGLY_RS04950
uniprot id: X5E9V9
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS05305
gene id: 1404245:CGLY_RS05305
uniprot id: X5DS71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS03990
gene id: 1404245:CGLY_RS03990
uniprot id: X5DPP7
names: Similarity
messages: Belongs to the WXG100 family.

1404245:CGLY RS01225
gene id: 1404245:CGLY_RS01225
uniprot id: X5E5E5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1404245:CGLY RS12760
gene id: 1404245:CGLY_RS12760
uniprot id: X5EEC3
names: Similarity
messages: Belongs to the FPG family.

1404245:CGLY RS07290
gene id: 1404245:CGLY_RS07290
uniprot id: X5DLB7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1404245:CGLY RS15800
gene id: 1404245:CGLY_RS15800
uniprot id: X5DY79
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1404245:CGLY RS05575
gene id: 1404245:CGLY_RS05575
uniprot id: X5DSC0
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS00540
gene id: 1404245:CGLY_RS00540
uniprot id: X5DHN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS02110
gene id: 1404245:CGLY_RS02110
uniprot id: X5E887
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1404245:CGLY RS08825
gene id: 1404245:CGLY_RS08825
uniprot id: X5DM51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1404245:CGLY RS06295
gene id: 1404245:CGLY_RS06295
uniprot id: X5EAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1404245:CGLY RS16265
gene id: 1404245:CGLY_RS16265
uniprot id: X5DWG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1404245:CGLY RS04685
gene id: 1404245:CGLY_RS04685
uniprot id: X5DJV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1404245:CGLY RS06895
gene id: 1404245:CGLY_RS06895
uniprot id: X5DT49
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS03725
gene id: 1404245:CGLY_RS03725
uniprot id: X5E951
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1404245:CGLY RS02400
gene id: 1404245:CGLY_RS02400
uniprot id: X5E652
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1404245:CGLY RS08390
gene id: 1404245:CGLY_RS08390
uniprot id: X5EBU9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1404245:CGLY RS06670
gene id: 1404245:CGLY_RS06670
uniprot id: X5DSY1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1404245:CGLY RS05795
gene id: 1404245:CGLY_RS05795
uniprot id: X5E828
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1404245:CGLY RS07255
gene id: 1404245:CGLY_RS07255
uniprot id: X5EB92
names: Similarity
messages: Belongs to the acylphosphatase family.

1404245:CGLY RS09545
gene id: 1404245:CGLY_RS09545
uniprot id: X5DMK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1404245:CGLY RS02705
gene id: 1404245:CGLY_RS02705
uniprot id: X5E6B5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1404245:CGLY RS06795
gene id: 1404245:CGLY_RS06795
uniprot id: X5DT31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1404245:CGLY RS01050
gene id: 1404245:CGLY_RS01050
uniprot id: X5E7J7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

1404245:CGLY RS00365
gene id: 1404245:CGLY_RS00365
uniprot id: X5DHK8
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS13805
gene id: 1404245:CGLY_RS13805
uniprot id: X5DX08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1404245:CGLY RS09860
gene id: 1404245:CGLY_RS09860
uniprot id: X5ECS5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1404245:CGLY RS10060
gene id: 1404245:CGLY_RS10060
uniprot id: X5DUW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1404245:CGLY RS09100
gene id: 1404245:CGLY_RS09100
uniprot id: X5EA28
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS05085
gene id: 1404245:CGLY_RS05085
uniprot id: X5E7P9
names: Similarity
messages: Belongs to the FPG family.

1404245:CGLY RS07700
gene id: 1404245:CGLY_RS07700
uniprot id: X5DRQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1404245:CGLY RS12500
gene id: 1404245:CGLY_RS12500
uniprot id: X5DUF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1404245:CGLY RS07005
gene id: 1404245:CGLY_RS07005
uniprot id: X5DRE7
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS09095
gene id: 1404245:CGLY_RS09095
uniprot id: X5DSI8
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS01250
gene id: 1404245:CGLY_RS01250
uniprot id: X5E5F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1404245:CGLY RS04625
gene id: 1404245:CGLY_RS04625
uniprot id: X5E9Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1404245:CGLY RS13615
gene id: 1404245:CGLY_RS13615
uniprot id: X5DWX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1404245:CGLY RS02960
gene id: 1404245:CGLY_RS02960
uniprot id: X5E8N7
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

1404245:CGLY RS07860
gene id: 1404245:CGLY_RS07860
uniprot id: X5EBJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS03095
gene id: 1404245:CGLY_RS03095
uniprot id: X5DP45
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1404245:CGLY RS04275
gene id: 1404245:CGLY_RS04275
uniprot id: X5E7B8
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS09340
gene id: 1404245:CGLY_RS09340
uniprot id: X5DSP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1404245:CGLY RS07630
gene id: 1404245:CGLY_RS07630
uniprot id: X5E952
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS10340
gene id: 1404245:CGLY_RS10340
uniprot id: X5DV21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1404245:CGLY RS07050
gene id: 1404245:CGLY_RS07050
uniprot id: X5DL78
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1404245:CGLY RS08240
gene id: 1404245:CGLY_RS08240
uniprot id: X5E9H5
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS06995
gene id: 1404245:CGLY_RS06995
uniprot id: X5DT65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1404245:CGLY RS08515
gene id: 1404245:CGLY_RS08515
uniprot id: X5EBY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1404245:CGLY RS09455
gene id: 1404245:CGLY_RS09455
uniprot id: X5ECL3
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS03740
gene id: 1404245:CGLY_RS03740
uniprot id: X5DPI1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1404245:CGLY RS11590
gene id: 1404245:CGLY_RS11590
uniprot id: X5DVU4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1404245:CGLY RS09360
gene id: 1404245:CGLY_RS09360
uniprot id: X5DMI1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1404245:CGLY RS13855
gene id: 1404245:CGLY_RS13855
uniprot id: X5DX22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1404245:CGLY RS04600
gene id: 1404245:CGLY_RS04600
uniprot id: X5E9P6
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1404245:CGLY RS11225
gene id: 1404245:CGLY_RS11225
uniprot id: X5DTS0
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS14120
gene id: 1404245:CGLY_RS14120
uniprot id: X5DPU7
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS10925
gene id: 1404245:CGLY_RS10925
uniprot id: X5EB30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS03855
gene id: 1404245:CGLY_RS03855
uniprot id: X5DRC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1404245:CGLY RS00980
gene id: 1404245:CGLY_RS00980
uniprot id: X5DPQ6
names: Similarity
messages: Belongs to the peptidase C56 family.

1404245:CGLY RS03370
gene id: 1404245:CGLY_RS03370
uniprot id: X5DPA5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1404245:CGLY RS00785
gene id: 1404245:CGLY_RS00785
uniprot id: X5DHT8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1404245:CGLY RS16550
gene id: 1404245:CGLY_RS16550
uniprot id: X5DMJ3
names: Similarity
messages: Belongs to the PhzA/PhzB family.

1404245:CGLY RS13460
gene id: 1404245:CGLY_RS13460
uniprot id: X5DWU8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1404245:CGLY RS00070
gene id: 1404245:CGLY_RS00070
uniprot id: X5DMF2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1404245:CGLY RS16255
gene id: 1404245:CGLY_RS16255
uniprot id: X5DYF6
names: Similarity
messages: Belongs to the ParB family.

1404245:CGLY RS07490
gene id: 1404245:CGLY_RS07490
uniprot id: X5DTE9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1404245:CGLY RS01665
gene id: 1404245:CGLY_RS01665
uniprot id: X5E819
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS15970
gene id: 1404245:CGLY_RS15970
uniprot id: X5EG62
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1404245:CGLY RS03445
gene id: 1404245:CGLY_RS03445
uniprot id: X5E6R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1404245:CGLY RS14545
gene id: 1404245:CGLY_RS14545
uniprot id: X5EFG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1404245:CGLY RS00690
gene id: 1404245:CGLY_RS00690
uniprot id: X5DMR4
names: Subcellular Location Annotation
messages: Cytoplasm

1404245:CGLY RS12800
gene id: 1404245:CGLY_RS12800
uniprot id: X5DUK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1404245:CGLY RS08555
gene id: 1404245:CGLY_RS08555
uniprot id: X5DS77
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1404245:CGLY RS09200
gene id: 1404245:CGLY_RS09200
uniprot id: X5DSK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1404245:CGLY RS08080
gene id: 1404245:CGLY_RS08080
uniprot id: X5E9F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1404245:CGLY RS13140
gene id: 1404245:CGLY_RS13140
uniprot id: X5DUR9
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS09575
gene id: 1404245:CGLY_RS09575
uniprot id: X5DST3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1404245:CGLY RS14385
gene id: 1404245:CGLY_RS14385
uniprot id: X5EFD8
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS06390
gene id: 1404245:CGLY_RS06390
uniprot id: X5E8G7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1404245:CGLY RS10760
gene id: 1404245:CGLY_RS10760
uniprot id: X5DVA1
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1404245:CGLY RS11365
gene id: 1404245:CGLY_RS11365
uniprot id: X5DVL9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1404245:CGLY RS08340
gene id: 1404245:CGLY_RS08340
uniprot id: X5EBU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1404245:CGLY RS16150
gene id: 1404245:CGLY_RS16150
uniprot id: X5DYD6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS00375
gene id: 1404245:CGLY_RS00375
uniprot id: X5E4W9
names: Similarity
messages: Belongs to the PhzA/PhzB family.

1404245:CGLY RS05945
gene id: 1404245:CGLY_RS05945
uniprot id: X5EAF4
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS12745
gene id: 1404245:CGLY_RS12745
uniprot id: X5DP60
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1404245:CGLY RS13810
gene id: 1404245:CGLY_RS13810
uniprot id: X5DPN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1404245:CGLY RS05675
gene id: 1404245:CGLY_RS05675
uniprot id: X5EA91
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1404245:CGLY RS13740
gene id: 1404245:CGLY_RS13740
uniprot id: X5DV37
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS11095
gene id: 1404245:CGLY_RS11095
uniprot id: X5DNC2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1404245:CGLY RS01150
gene id: 1404245:CGLY_RS01150
uniprot id: X5E5D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS07120
gene id: 1404245:CGLY_RS07120
uniprot id: X5E8W5
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

1404245:CGLY RS04960
gene id: 1404245:CGLY_RS04960
uniprot id: X5DK06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1404245:CGLY RS00600
gene id: 1404245:CGLY_RS00600
uniprot id: X5E518
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1404245:CGLY RS10695
gene id: 1404245:CGLY_RS10695
uniprot id: X5DTF5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1404245:CGLY RS06735
gene id: 1404245:CGLY_RS06735
uniprot id: X5E8Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1404245:CGLY RS07540
gene id: 1404245:CGLY_RS07540
uniprot id: X5DTF7
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1404245:CGLY RS02520
gene id: 1404245:CGLY_RS02520
uniprot id: X5DIR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1404245:CGLY RS03545
gene id: 1404245:CGLY_RS03545
uniprot id: X5E6T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1404245:CGLY RS10770
gene id: 1404245:CGLY_RS10770
uniprot id: X5DTH0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1404245:CGLY RS16205
gene id: 1404245:CGLY_RS16205
uniprot id: X5DYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1404245:CGLY RS06630
gene id: 1404245:CGLY_RS06630
uniprot id: X5E8M6
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS02620
gene id: 1404245:CGLY_RS02620
uniprot id: X5DIT2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS01015
gene id: 1404245:CGLY_RS01015
uniprot id: X5DMX9
names: Similarity
messages: Belongs to the Dps family.

1404245:CGLY RS11100
gene id: 1404245:CGLY_RS11100
uniprot id: X5DTP3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1404245:CGLY RS03750
gene id: 1404245:CGLY_RS03750
uniprot id: X5E957
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1404245:CGLY RS00015
gene id: 1404245:CGLY_RS00015
uniprot id: X5DHF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1404245:CGLY RS06510
gene id: 1404245:CGLY_RS06510
uniprot id: X5E8J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1404245:CGLY RS02555
gene id: 1404245:CGLY_RS02555
uniprot id: X5E684
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1404245:CGLY RS15565
gene id: 1404245:CGLY_RS15565
uniprot id: X5DW11
names: Similarity
messages: Belongs to the universal stress protein A family.

1404245:CGLY RS11390
gene id: 1404245:CGLY_RS11390
uniprot id: X5DVM7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1404245:CGLY RS09320
gene id: 1404245:CGLY_RS09320
uniprot id: X5EA88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1404245:CGLY RS09310
gene id: 1404245:CGLY_RS09310
uniprot id: X5DMH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS11170
gene id: 1404245:CGLY_RS11170
uniprot id: X5DND3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1404245:CGLY RS17915
gene id: 1404245:CGLY_RS17915
uniprot id: X5DMM7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1404245:CGLY RS12085
gene id: 1404245:CGLY_RS12085
uniprot id: X5EE17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS08540
gene id: 1404245:CGLY_RS08540
uniprot id: X5EBY8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS00885
gene id: 1404245:CGLY_RS00885
uniprot id: X5DHV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1404245:CGLY RS12490
gene id: 1404245:CGLY_RS12490
uniprot id: X5DWD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1404245:CGLY RS01835
gene id: 1404245:CGLY_RS01835
uniprot id: X5E5V9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1404245:CGLY RS07480
gene id: 1404245:CGLY_RS07480
uniprot id: X5E925
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS05025
gene id: 1404245:CGLY_RS05025
uniprot id: X5DS19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1404245:CGLY RS12780
gene id: 1404245:CGLY_RS12780
uniprot id: X5EC50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1404245:CGLY RS06075
gene id: 1404245:CGLY_RS06075
uniprot id: X5DSK3
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS05115
gene id: 1404245:CGLY_RS05115
uniprot id: X5E9Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1404245:CGLY RS04650
gene id: 1404245:CGLY_RS04650
uniprot id: X5E9Q6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS08290
gene id: 1404245:CGLY_RS08290
uniprot id: X5E9I4
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS09760
gene id: 1404245:CGLY_RS09760
uniprot id: X5ECR3
names: Similarity
messages: Belongs to the YggT family.

1404245:CGLY RS12505
gene id: 1404245:CGLY_RS12505
uniprot id: X5EBZ7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1404245:CGLY RS03885
gene id: 1404245:CGLY_RS03885
uniprot id: X5DJG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1404245:CGLY RS08230
gene id: 1404245:CGLY_RS08230
uniprot id: X5DLT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1404245:CGLY RS03420
gene id: 1404245:CGLY_RS03420
uniprot id: X5E6Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1404245:CGLY RS13350
gene id: 1404245:CGLY_RS13350
uniprot id: X5ECF2
names: Similarity
messages: Belongs to the FPG family.

1404245:CGLY RS04235
gene id: 1404245:CGLY_RS04235
uniprot id: X5DRN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1404245:CGLY RS08460
gene id: 1404245:CGLY_RS08460
uniprot id: X5E9M1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1404245:CGLY RS03850
gene id: 1404245:CGLY_RS03850
uniprot id: X5E982
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1404245:CGLY RS03570
gene id: 1404245:CGLY_RS03570
uniprot id: X5E6U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1404245:CGLY RS02430
gene id: 1404245:CGLY_RS02430
uniprot id: X5E8D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS08160
gene id: 1404245:CGLY_RS08160
uniprot id: X5DRZ7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS12265
gene id: 1404245:CGLY_RS12265
uniprot id: X5DUC0
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS11630
gene id: 1404245:CGLY_RS11630
uniprot id: X5EBJ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1404245:CGLY RS14100
gene id: 1404245:CGLY_RS14100
uniprot id: X5DVA2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1404245:CGLY RS12445
gene id: 1404245:CGLY_RS12445
uniprot id: X5DP06
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS08235
gene id: 1404245:CGLY_RS08235
uniprot id: X5DS13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1404245:CGLY RS07225
gene id: 1404245:CGLY_RS07225
uniprot id: X5E8Y3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1404245:CGLY RS10490
gene id: 1404245:CGLY_RS10490
uniprot id: X5DN09
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS08885
gene id: 1404245:CGLY_RS08885
uniprot id: X5E9X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1404245:CGLY RS07000
gene id: 1404245:CGLY_RS07000
uniprot id: X5DL68
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS07800
gene id: 1404245:CGLY_RS07800
uniprot id: X5DRT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1404245:CGLY RS07920
gene id: 1404245:CGLY_RS07920
uniprot id: X5DLN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1404245:CGLY RS12510
gene id: 1404245:CGLY_RS12510
uniprot id: X5EE79
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1404245:CGLY RS09325
gene id: 1404245:CGLY_RS09325
uniprot id: X5ECJ2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1404245:CGLY RS06610
gene id: 1404245:CGLY_RS06610
uniprot id: X5EAW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1404245:CGLY RS07270
gene id: 1404245:CGLY_RS07270
uniprot id: X5DRH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1404245:CGLY RS11745
gene id: 1404245:CGLY_RS11745
uniprot id: X5EDV2
names: Similarity
messages: Belongs to the TPP enzyme family.

1404245:CGLY RS00195
gene id: 1404245:CGLY_RS00195
uniprot id: X5DMG3
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS14720
gene id: 1404245:CGLY_RS14720
uniprot id: X5ED98
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1404245:CGLY RS09330
gene id: 1404245:CGLY_RS09330
uniprot id: X5DUI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1404245:CGLY RS03110
gene id: 1404245:CGLY_RS03110
uniprot id: X5DQY0
names: Similarity
messages: Belongs to the AccD/PCCB family.

1404245:CGLY RS16235
gene id: 1404245:CGLY_RS16235
uniprot id: X5DR08
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1404245:CGLY RS07820
gene id: 1404245:CGLY_RS07820
uniprot id: X5DLL4
names: Similarity
messages: Belongs to the PspA/IM30 family.

1404245:CGLY RS12665
gene id: 1404245:CGLY_RS12665
uniprot id: X5DWG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1404245:CGLY RS10175
gene id: 1404245:CGLY_RS10175
uniprot id: X5DUZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1404245:CGLY RS04630
gene id: 1404245:CGLY_RS04630
uniprot id: X5DRU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1404245:CGLY RS02510
gene id: 1404245:CGLY_RS02510
uniprot id: X5E8F3
names: Similarity
messages: Belongs to the AccD/PCCB family.

1404245:CGLY RS07440
gene id: 1404245:CGLY_RS07440
uniprot id: X5DTE0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1404245:CGLY RS09295
gene id: 1404245:CGLY_RS09295
uniprot id: X5EA83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1404245:CGLY RS05120
gene id: 1404245:CGLY_RS05120
uniprot id: X5DS35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1404245:CGLY RS10780
gene id: 1404245:CGLY_RS10780
uniprot id: X5ED71
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1404245:CGLY RS08225
gene id: 1404245:CGLY_RS08225
uniprot id: X5DTS5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1404245:CGLY RS08275
gene id: 1404245:CGLY_RS08275
uniprot id: X5DTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1404245:CGLY RS06890
gene id: 1404245:CGLY_RS06890
uniprot id: X5EB33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS13490
gene id: 1404245:CGLY_RS13490
uniprot id: X5DPH9
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS02405
gene id: 1404245:CGLY_RS02405
uniprot id: X5E8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS03610
gene id: 1404245:CGLY_RS03610
uniprot id: X5DJA6
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1404245:CGLY RS08220
gene id: 1404245:CGLY_RS08220
uniprot id: X5EBQ8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1404245:CGLY RS16065
gene id: 1404245:CGLY_RS16065
uniprot id: X5EDX9
names: Similarity
messages: Belongs to the thioredoxin family.

1404245:CGLY RS03260
gene id: 1404245:CGLY_RS03260
uniprot id: X5DR10
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS03620
gene id: 1404245:CGLY_RS03620
uniprot id: X5E6V3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1404245:CGLY RS08100
gene id: 1404245:CGLY_RS08100
uniprot id: X5DRZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1404245:CGLY RS15495
gene id: 1404245:CGLY_RS15495
uniprot id: X5EDN1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1404245:CGLY RS07830
gene id: 1404245:CGLY_RS07830
uniprot id: X5E997
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS08440
gene id: 1404245:CGLY_RS08440
uniprot id: X5EBW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1404245:CGLY RS04755
gene id: 1404245:CGLY_RS04755
uniprot id: X5DRW9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1404245:CGLY RS06665
gene id: 1404245:CGLY_RS06665
uniprot id: X5EAX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1404245:CGLY RS11400
gene id: 1404245:CGLY_RS11400
uniprot id: X5DTW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1404245:CGLY RS08625
gene id: 1404245:CGLY_RS08625
uniprot id: X5DM10
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1404245:CGLY RS12690
gene id: 1404245:CGLY_RS12690
uniprot id: X5DWH1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1404245:CGLY RS04245
gene id: 1404245:CGLY_RS04245
uniprot id: X5DPW6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1404245:CGLY RS04935
gene id: 1404245:CGLY_RS04935
uniprot id: X5DK01
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1404245:CGLY RS09805
gene id: 1404245:CGLY_RS09805
uniprot id: X5EAG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS13065
gene id: 1404245:CGLY_RS13065
uniprot id: X5DPB2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1404245:CGLY RS03915
gene id: 1404245:CGLY_RS03915
uniprot id: X5DPM7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1404245:CGLY RS12590
gene id: 1404245:CGLY_RS12590
uniprot id: X5DWF1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1404245:CGLY RS04455
gene id: 1404245:CGLY_RS04455
uniprot id: X5DRR8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS01040
gene id: 1404245:CGLY_RS01040
uniprot id: X5DMY5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1404245:CGLY RS10520
gene id: 1404245:CGLY_RS10520
uniprot id: X5DTB2
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS03425
gene id: 1404245:CGLY_RS03425
uniprot id: X5E8Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1404245:CGLY RS02135
gene id: 1404245:CGLY_RS02135
uniprot id: X5E890
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-67 and Arg-70) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1404245:CGLY RS01740
gene id: 1404245:CGLY_RS01740
uniprot id: X5E830
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1404245:CGLY RS08345
gene id: 1404245:CGLY_RS08345
uniprot id: X5DTV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1404245:CGLY RS07140
gene id: 1404245:CGLY_RS07140
uniprot id: X5DL89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1404245:CGLY RS12890
gene id: 1404245:CGLY_RS12890
uniprot id: X5EEE8
names: Similarity
messages: Belongs to the citrate synthase family.

1404245:CGLY RS00330
gene id: 1404245:CGLY_RS00330
uniprot id: X5E762
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1404245:CGLY RS04285
gene id: 1404245:CGLY_RS04285
uniprot id: X5DRP1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1404245:CGLY RS14530
gene id: 1404245:CGLY_RS14530
uniprot id: X5DQ39
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS03255
gene id: 1404245:CGLY_RS03255
uniprot id: X5E8V1
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS15400
gene id: 1404245:CGLY_RS15400
uniprot id: X5EFU9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1404245:CGLY RS07770
gene id: 1404245:CGLY_RS07770
uniprot id: X5DLK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1404245:CGLY RS11210
gene id: 1404245:CGLY_RS11210
uniprot id: X5EDI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1404245:CGLY RS01035
gene id: 1404245:CGLY_RS01035
uniprot id: X5DHY6
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS07990
gene id: 1404245:CGLY_RS07990
uniprot id: X5DTN9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1404245:CGLY RS06505
gene id: 1404245:CGLY_RS06505
uniprot id: X5DR50
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS07690
gene id: 1404245:CGLY_RS07690
uniprot id: X5DTI5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1404245:CGLY RS14525
gene id: 1404245:CGLY_RS14525
uniprot id: X5DXL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1404245:CGLY RS08300
gene id: 1404245:CGLY_RS08300
uniprot id: X5DLU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1404245:CGLY RS00625
gene id: 1404245:CGLY_RS00625
uniprot id: X5E523
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1404245:CGLY RS13310
gene id: 1404245:CGLY_RS13310
uniprot id: X5DWS3
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1404245:CGLY RS02420
gene id: 1404245:CGLY_RS02420
uniprot id: X5DNQ4
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1404245:CGLY RS07705
gene id: 1404245:CGLY_RS07705
uniprot id: X5E967
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1404245:CGLY RS01230
gene id: 1404245:CGLY_RS01230
uniprot id: X5E7N3
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1404245:CGLY RS03930
gene id: 1404245:CGLY_RS03930
uniprot id: X5DRD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1404245:CGLY RS13955
gene id: 1404245:CGLY_RS13955
uniprot id: X5DX51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1404245:CGLY RS11955
gene id: 1404245:CGLY_RS11955
uniprot id: X5DW52
names: Similarity
messages: Belongs to the asp23 family.

1404245:CGLY RS12815
gene id: 1404245:CGLY_RS12815
uniprot id: X5EED3
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS14055
gene id: 1404245:CGLY_RS14055
uniprot id: X5ECW3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1404245:CGLY RS05040
gene id: 1404245:CGLY_RS05040
uniprot id: X5E7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1404245:CGLY RS09700
gene id: 1404245:CGLY_RS09700
uniprot id: X5DSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1404245:CGLY RS01450
gene id: 1404245:CGLY_RS01450
uniprot id: X5DQ07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS06615
gene id: 1404245:CGLY_RS06615
uniprot id: X5DSX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1404245:CGLY RS12165
gene id: 1404245:CGLY_RS12165
uniprot id: X5EBU2
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS13165
gene id: 1404245:CGLY_RS13165
uniprot id: X5DPC5
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1404245:CGLY RS08675
gene id: 1404245:CGLY_RS08675
uniprot id: X5DM19
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS02115
gene id: 1404245:CGLY_RS02115
uniprot id: X5DQE6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1404245:CGLY RS12370
gene id: 1404245:CGLY_RS12370
uniprot id: X5DUD5
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS14080
gene id: 1404245:CGLY_RS14080
uniprot id: X5ECW9
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS00550
gene id: 1404245:CGLY_RS00550
uniprot id: X5E508
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS15955
gene id: 1404245:CGLY_RS15955
uniprot id: X5DQU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS04215
gene id: 1404245:CGLY_RS04215
uniprot id: X5DJN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1404245:CGLY RS06935
gene id: 1404245:CGLY_RS06935
uniprot id: X5E8T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS09430
gene id: 1404245:CGLY_RS09430
uniprot id: X5ECK9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1404245:CGLY RS01095
gene id: 1404245:CGLY_RS01095
uniprot id: X5E5B9
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1404245:CGLY RS12290
gene id: 1404245:CGLY_RS12290
uniprot id: X5DUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1404245:CGLY RS02535
gene id: 1404245:CGLY_RS02535
uniprot id: X5E8F7
names: Similarity
messages: Belongs to the DapA family.

1404245:CGLY RS02310
gene id: 1404245:CGLY_RS02310
uniprot id: X5DQH3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1404245:CGLY RS10300
gene id: 1404245:CGLY_RS10300
uniprot id: X5DT64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1404245:CGLY RS07580
gene id: 1404245:CGLY_RS07580
uniprot id: X5E941
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS04075
gene id: 1404245:CGLY_RS04075
uniprot id: X5E770
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1404245:CGLY RS02465
gene id: 1404245:CGLY_RS02465
uniprot id: X5DQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS01080
gene id: 1404245:CGLY_RS01080
uniprot id: X5DPS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1404245:CGLY RS05330
gene id: 1404245:CGLY_RS05330
uniprot id: X5DS73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS07220
gene id: 1404245:CGLY_RS07220
uniprot id: X5DRH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1404245:CGLY RS01430
gene id: 1404245:CGLY_RS01430
uniprot id: X5DI62
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1404245:CGLY RS04595
gene id: 1404245:CGLY_RS04595
uniprot id: X5E7G5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1404245:CGLY RS08450
gene id: 1404245:CGLY_RS08450
uniprot id: X5DLX7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1404245:CGLY RS08780
gene id: 1404245:CGLY_RS08780
uniprot id: X5DSB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1404245:CGLY RS11285
gene id: 1404245:CGLY_RS11285
uniprot id: X5EDJ8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1404245:CGLY RS04380
gene id: 1404245:CGLY_RS04380
uniprot id: X5DJR1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1404245:CGLY RS12205
gene id: 1404245:CGLY_RS12205
uniprot id: X5DW88
names: Subcellular Location Annotation
messages: Cell membrane

1404245:CGLY RS13265
gene id: 1404245:CGLY_RS13265
uniprot id: X5DPE1
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS01745
gene id: 1404245:CGLY_RS01745
uniprot id: X5DQ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1404245:CGLY RS02595
gene id: 1404245:CGLY_RS02595
uniprot id: X5DIS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1404245:CGLY RS03840
gene id: 1404245:CGLY_RS03840
uniprot id: X5DPK6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS09730
gene id: 1404245:CGLY_RS09730
uniprot id: X5EAF3
names: Similarity
messages: Belongs to the asparaginase 1 family.

1404245:CGLY RS13795
gene id: 1404245:CGLY_RS13795
uniprot id: X5ECQ4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1404245:CGLY RS06055
gene id: 1404245:CGLY_RS06055
uniprot id: X5DKL1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1404245:CGLY RS00845
gene id: 1404245:CGLY_RS00845
uniprot id: X5E569
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1404245:CGLY RS07855
gene id: 1404245:CGLY_RS07855
uniprot id: X5E9A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1404245:CGLY RS07760
gene id: 1404245:CGLY_RS07760
uniprot id: X5EBI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1404245:CGLY RS03870
gene id: 1404245:CGLY_RS03870
uniprot id: X5E721
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1404245:CGLY RS00320
gene id: 1404245:CGLY_RS00320
uniprot id: X5DMI2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1404245:CGLY RS00405
gene id: 1404245:CGLY_RS00405
uniprot id: X5E775
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS02590
gene id: 1404245:CGLY_RS02590
uniprot id: X5DQM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1404245:CGLY RS10650
gene id: 1404245:CGLY_RS10650
uniprot id: X5EAW9
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1404245:CGLY RS02490
gene id: 1404245:CGLY_RS02490
uniprot id: X5DQK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1404245:CGLY RS03525
gene id: 1404245:CGLY_RS03525
uniprot id: X5E910
names: Similarity
messages: Belongs to the asp23 family.

1404245:CGLY RS00115
gene id: 1404245:CGLY_RS00115
uniprot id: X5E726
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1404245:CGLY RS09535
gene id: 1404245:CGLY_RS09535
uniprot id: X5ECM6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS01845
gene id: 1404245:CGLY_RS01845
uniprot id: X5DQ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS14020
gene id: 1404245:CGLY_RS14020
uniprot id: X5DPT0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1404245:CGLY RS11665
gene id: 1404245:CGLY_RS11665
uniprot id: X5DVW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1404245:CGLY RS03400
gene id: 1404245:CGLY_RS03400
uniprot id: X5E8Y2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1404245:CGLY RS03330
gene id: 1404245:CGLY_RS03330
uniprot id: X5E8W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1404245:CGLY RS08695
gene id: 1404245:CGLY_RS08695
uniprot id: X5DU12
names: Similarity
messages: Belongs to the UPF0098 family.

1404245:CGLY RS04260
gene id: 1404245:CGLY_RS04260
uniprot id: X5DRN9
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS12585
gene id: 1404245:CGLY_RS12585
uniprot id: X5EE91
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1404245:CGLY RS03405
gene id: 1404245:CGLY_RS03405
uniprot id: X5DR36
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1404245:CGLY RS09070
gene id: 1404245:CGLY_RS09070
uniprot id: X5DSI2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS03890
gene id: 1404245:CGLY_RS03890
uniprot id: X5DPM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1404245:CGLY RS02335
gene id: 1404245:CGLY_RS02335
uniprot id: X5DQH7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS03720
gene id: 1404245:CGLY_RS03720
uniprot id: X5E6Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1404245:CGLY RS03865
gene id: 1404245:CGLY_RS03865
uniprot id: X5DPL5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1404245:CGLY RS03785
gene id: 1404245:CGLY_RS03785
uniprot id: X5DJD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1404245:CGLY RS08525
gene id: 1404245:CGLY_RS08525
uniprot id: X5DLZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1404245:CGLY RS07160
gene id: 1404245:CGLY_RS07160
uniprot id: X5DT92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1404245:CGLY RS13275
gene id: 1404245:CGLY_RS13275
uniprot id: X5ECD3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1404245:CGLY RS02640
gene id: 1404245:CGLY_RS02640
uniprot id: X5DQN5
names: Similarity
messages: Belongs to the catalase family.

1404245:CGLY RS07015
gene id: 1404245:CGLY_RS07015
uniprot id: X5EB54
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1404245:CGLY RS13305
gene id: 1404245:CGLY_RS13305
uniprot id: X5EEK7
names: Similarity
messages: Belongs to the PrpD family.

1404245:CGLY RS04280
gene id: 1404245:CGLY_RS04280
uniprot id: X5E9J7
names: Similarity
messages: Belongs to the peptidase S11 family.

1404245:CGLY RS07430
gene id: 1404245:CGLY_RS07430
uniprot id: X5E918
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1404245:CGLY RS04785
gene id: 1404245:CGLY_RS04785
uniprot id: X5DJX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

1404245:CGLY RS01880
gene id: 1404245:CGLY_RS01880
uniprot id: X5E5W5
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS00385
gene id: 1404245:CGLY_RS00385
uniprot id: X5DPD9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1404245:CGLY RS00830
gene id: 1404245:CGLY_RS00830
uniprot id: X5DPM6
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS05525
gene id: 1404245:CGLY_RS05525
uniprot id: X5DSB1
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS10470
gene id: 1404245:CGLY_RS10470
uniprot id: X5DN04
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS13760
gene id: 1404245:CGLY_RS13760
uniprot id: X5DPM9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1404245:CGLY RS08210
gene id: 1404245:CGLY_RS08210
uniprot id: X5DS07
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1404245:CGLY RS15535
gene id: 1404245:CGLY_RS15535
uniprot id: X5DQL6
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS01205
gene id: 1404245:CGLY_RS01205
uniprot id: X5E7M9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1404245:CGLY RS04370
gene id: 1404245:CGLY_RS04370
uniprot id: X5E9K7
names: Similarity
messages: Belongs to the peptidase C40 family.

1404245:CGLY RS06725
gene id: 1404245:CGLY_RS06725
uniprot id: X5DL37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1404245:CGLY RS07915
gene id: 1404245:CGLY_RS07915
uniprot id: X5DTM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1404245:CGLY RS08635
gene id: 1404245:CGLY_RS08635
uniprot id: X5E9R5
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1404245:CGLY RS07260
gene id: 1404245:CGLY_RS07260
uniprot id: X5DTA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1404245:CGLY RS16380
gene id: 1404245:CGLY_RS16380
uniprot id: X5DYK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS11420
gene id: 1404245:CGLY_RS11420
uniprot id: X5DNI2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1404245:CGLY RS13905
gene id: 1404245:CGLY_RS13905
uniprot id: X5DX36
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1404245:CGLY RS01245
gene id: 1404245:CGLY_RS01245
uniprot id: X5DN32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1404245:CGLY RS12035
gene id: 1404245:CGLY_RS12035
uniprot id: X5DW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS08920
gene id: 1404245:CGLY_RS08920
uniprot id: X5DM74
names: Similarity
messages: Belongs to the UPF0045 family.

1404245:CGLY RS01855
gene id: 1404245:CGLY_RS01855
uniprot id: X5DNH6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1404245:CGLY RS06205
gene id: 1404245:CGLY_RS06205
uniprot id: X5DKN9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1404245:CGLY RS10410
gene id: 1404245:CGLY_RS10410
uniprot id: X5ED08
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1404245:CGLY RS15865
gene id: 1404245:CGLY_RS15865
uniprot id: X5EDU0
names: Similarity
messages: Belongs to the CFA/CMAS family.

1404245:CGLY RS04440
gene id: 1404245:CGLY_RS04440
uniprot id: X5DPZ1
names: Similarity
messages: Belongs to the AccD/PCCB family.

1404245:CGLY RS03900
gene id: 1404245:CGLY_RS03900
uniprot id: X5E995
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1404245:CGLY RS06180
gene id: 1404245:CGLY_RS06180
uniprot id: X5DKN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS10020
gene id: 1404245:CGLY_RS10020
uniprot id: X5DSZ9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1404245:CGLY RS01805
gene id: 1404245:CGLY_RS01805
uniprot id: X5DNG9
names: Subunit
messages: Homotetramer.

1404245:CGLY RS02615
gene id: 1404245:CGLY_RS02615
uniprot id: X5DQN0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1404245:CGLY RS04575
gene id: 1404245:CGLY_RS04575
uniprot id: X5E9P2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1404245:CGLY RS06835
gene id: 1404245:CGLY_RS06835
uniprot id: X5E8R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1404245:CGLY RS12415
gene id: 1404245:CGLY_RS12415
uniprot id: X5DWC0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1404245:CGLY RS00665
gene id: 1404245:CGLY_RS00665
uniprot id: X5DMQ9
names: Similarity
messages: Belongs to the group II decarboxylase family.

1404245:CGLY RS12700
gene id: 1404245:CGLY_RS12700
uniprot id: X5DUI6
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1404245:CGLY RS14690
gene id: 1404245:CGLY_RS14690
uniprot id: X5DVK8
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1404245:CGLY RS11330
gene id: 1404245:CGLY_RS11330
uniprot id: X5EBD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1404245:CGLY RS13150
gene id: 1404245:CGLY_RS13150
uniprot id: X5ECB0
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1404245:CGLY RS09745
gene id: 1404245:CGLY_RS09745
uniprot id: X5DMN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1404245:CGLY RS10670
gene id: 1404245:CGLY_RS10670
uniprot id: X5DTF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1404245:CGLY RS11255
gene id: 1404245:CGLY_RS11255
uniprot id: X5EBB0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1404245:CGLY RS13485
gene id: 1404245:CGLY_RS13485
uniprot id: X5DWV3
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS14580
gene id: 1404245:CGLY_RS14580
uniprot id: X5DQ47
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1404245:CGLY RS08455
gene id: 1404245:CGLY_RS08455
uniprot id: X5DS59
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1404245:CGLY RS06710
gene id: 1404245:CGLY_RS06710
uniprot id: X5E8Q5
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS09410
gene id: 1404245:CGLY_RS09410
uniprot id: X5DUJ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1404245:CGLY RS05000
gene id: 1404245:CGLY_RS05000
uniprot id: X5E9W7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1404245:CGLY RS10860
gene id: 1404245:CGLY_RS10860
uniprot id: X5DVC2
names: Similarity
messages: Belongs to the histone deacetylase family.

1404245:CGLY RS09880
gene id: 1404245:CGLY_RS09880
uniprot id: X5ECS9
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

1404245:CGLY RS03450
gene id: 1404245:CGLY_RS03450
uniprot id: X5E8Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1404245:CGLY RS11525
gene id: 1404245:CGLY_RS11525
uniprot id: X5DTZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1404245:CGLY RS02700
gene id: 1404245:CGLY_RS02700
uniprot id: X5DNU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1404245:CGLY RS01110
gene id: 1404245:CGLY_RS01110
uniprot id: X5DHZ7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1404245:CGLY RS03910
gene id: 1404245:CGLY_RS03910
uniprot id: X5DJG5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1404245:CGLY RS07250
gene id: 1404245:CGLY_RS07250
uniprot id: X5E8Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS02460
gene id: 1404245:CGLY_RS02460
uniprot id: X5E8E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS16005
gene id: 1404245:CGLY_RS16005
uniprot id: X5DQV9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1404245:CGLY RS01505
gene id: 1404245:CGLY_RS01505
uniprot id: X5DN95
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1404245:CGLY RS09385
gene id: 1404245:CGLY_RS09385
uniprot id: X5DUJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1404245:CGLY RS06240
gene id: 1404245:CGLY_RS06240
uniprot id: X5E8C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1404245:CGLY RS06230
gene id: 1404245:CGLY_RS06230
uniprot id: X5DKP5
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS06790
gene id: 1404245:CGLY_RS06790
uniprot id: X5EB15
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1404245:CGLY RS08660
gene id: 1404245:CGLY_RS08660
uniprot id: X5E9S2
names: Similarity
messages: Belongs to the peptidase C40 family.

1404245:CGLY RS13645
gene id: 1404245:CGLY_RS13645
uniprot id: X5DPK3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1404245:CGLY RS06010
gene id: 1404245:CGLY_RS06010
uniprot id: X5DQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS11755
gene id: 1404245:CGLY_RS11755
uniprot id: X5DNP6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1404245:CGLY RS11395
gene id: 1404245:CGLY_RS11395
uniprot id: X5DNH7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1404245:CGLY RS03005
gene id: 1404245:CGLY_RS03005
uniprot id: X5E8P6
names: Cofactor
messages: Can also use Mn(2+) ion.

1404245:CGLY RS03540
gene id: 1404245:CGLY_RS03540
uniprot id: X5DPE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1404245:CGLY RS06990
gene id: 1404245:CGLY_RS06990
uniprot id: X5EB50
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1404245:CGLY RS07720
gene id: 1404245:CGLY_RS07720
uniprot id: X5DLJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1404245:CGLY RS00710
gene id: 1404245:CGLY_RS00710
uniprot id: X5DHS4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1404245:CGLY RS07785
gene id: 1404245:CGLY_RS07785
uniprot id: X5EBI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1404245:CGLY RS10705
gene id: 1404245:CGLY_RS10705
uniprot id: X5ED54
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1404245:CGLY RS03860
gene id: 1404245:CGLY_RS03860
uniprot id: X5DJF4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1404245:CGLY RS03310
gene id: 1404245:CGLY_RS03310
uniprot id: X5DR20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1404245:CGLY RS02410
gene id: 1404245:CGLY_RS02410
uniprot id: X5DQJ2
names: Similarity
messages: Belongs to the universal stress protein A family.

1404245:CGLY RS13105
gene id: 1404245:CGLY_RS13105
uniprot id: X5DWN4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1404245:CGLY RS04485
gene id: 1404245:CGLY_RS04485
uniprot id: X5DJS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS05870
gene id: 1404245:CGLY_RS05870
uniprot id: X5EAD5
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1404245:CGLY RS05365
gene id: 1404245:CGLY_RS05365
uniprot id: X5E7U7
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS05345
gene id: 1404245:CGLY_RS05345
uniprot id: X5E7U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS07145
gene id: 1404245:CGLY_RS07145
uniprot id: X5DRG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1404245:CGLY RS08505
gene id: 1404245:CGLY_RS08505
uniprot id: X5DS67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1404245:CGLY RS14375
gene id: 1404245:CGLY_RS14375
uniprot id: X5DVH3
names: Similarity
messages: Belongs to the arginase family.

1404245:CGLY RS14575
gene id: 1404245:CGLY_RS14575
uniprot id: X5DXM8
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS07865
gene id: 1404245:CGLY_RS07865
uniprot id: X5DTL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS12120
gene id: 1404245:CGLY_RS12120
uniprot id: X5DNV5
names: Similarity
messages: Belongs to the HsdR family.

1404245:CGLY RS05150
gene id: 1404245:CGLY_RS05150
uniprot id: X5DS39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS08650
gene id: 1404245:CGLY_RS08650
uniprot id: X5DM15
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1404245:CGLY RS09960
gene id: 1404245:CGLY_RS09960
uniprot id: X5DUU8
names: Similarity
messages: Belongs to the asparagine synthetase family.

1404245:CGLY RS11930
gene id: 1404245:CGLY_RS11930
uniprot id: X5EBQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS04050
gene id: 1404245:CGLY_RS04050
uniprot id: X5E765
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1404245:CGLY RS13655
gene id: 1404245:CGLY_RS13655
uniprot id: X5ECL6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1404245:CGLY RS13425
gene id: 1404245:CGLY_RS13425
uniprot id: X5ECG6
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS05850
gene id: 1404245:CGLY_RS05850
uniprot id: X5DSG6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1404245:CGLY RS13260
gene id: 1404245:CGLY_RS13260
uniprot id: X5DWR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1404245:CGLY RS02215
gene id: 1404245:CGLY_RS02215
uniprot id: X5E8A2
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1404245:CGLY RS05075
gene id: 1404245:CGLY_RS05075
uniprot id: X5DK28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS07175
gene id: 1404245:CGLY_RS07175
uniprot id: X5E8X4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1404245:CGLY RS09190
gene id: 1404245:CGLY_RS09190
uniprot id: X5DUD0
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS04975
gene id: 1404245:CGLY_RS04975
uniprot id: X5E9W3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1404245:CGLY RS03055
gene id: 1404245:CGLY_RS03055
uniprot id: X5E8Q2
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1404245:CGLY RS06120
gene id: 1404245:CGLY_RS06120
uniprot id: X5EAJ1
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS00705
gene id: 1404245:CGLY_RS00705
uniprot id: X5DPK0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1404245:CGLY RS02390
gene id: 1404245:CGLY_RS02390
uniprot id: X5DIP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1404245:CGLY RS00535
gene id: 1404245:CGLY_RS00535
uniprot id: X5DPG6
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

1404245:CGLY RS06080
gene id: 1404245:CGLY_RS06080
uniprot id: X5DKL6
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS01940
gene id: 1404245:CGLY_RS01940
uniprot id: X5E862
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS02850
gene id: 1404245:CGLY_RS02850
uniprot id: X5DNY4
names: Subcellular Location Annotation
messages: Cytoplasm

1404245:CGLY RS06860
gene id: 1404245:CGLY_RS06860
uniprot id: X5E8S3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1404245:CGLY RS04060
gene id: 1404245:CGLY_RS04060
uniprot id: X5DRG8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1404245:CGLY RS11680
gene id: 1404245:CGLY_RS11680
uniprot id: X5EBK0
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

1404245:CGLY RS06495
gene id: 1404245:CGLY_RS06495
uniprot id: X5DSU6
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1404245:CGLY RS09475
gene id: 1404245:CGLY_RS09475
uniprot id: X5EAB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1404245:CGLY RS08365
gene id: 1404245:CGLY_RS08365
uniprot id: X5EBU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1404245:CGLY RS09205
gene id: 1404245:CGLY_RS09205
uniprot id: X5EA51
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1404245:CGLY RS04705
gene id: 1404245:CGLY_RS04705
uniprot id: X5DRW0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1404245:CGLY RS08205
gene id: 1404245:CGLY_RS08205
uniprot id: X5DLS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1404245:CGLY RS03535
gene id: 1404245:CGLY_RS03535
uniprot id: X5DJ90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1404245:CGLY RS03265
gene id: 1404245:CGLY_RS03265
uniprot id: X5DJ40
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1404245:CGLY RS14700
gene id: 1404245:CGLY_RS14700
uniprot id: X5EFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS11505
gene id: 1404245:CGLY_RS11505
uniprot id: X5EBG5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1404245:CGLY RS07950
gene id: 1404245:CGLY_RS07950
uniprot id: X5DRW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1404245:CGLY RS07320
gene id: 1404245:CGLY_RS07320
uniprot id: X5DRI5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1404245:CGLY RS00310
gene id: 1404245:CGLY_RS00310
uniprot id: X5DPC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1404245:CGLY RS04095
gene id: 1404245:CGLY_RS04095
uniprot id: X5DPR8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1404245:CGLY RS16270
gene id: 1404245:CGLY_RS16270
uniprot id: X5EE30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1404245:CGLY RS14115
gene id: 1404245:CGLY_RS14115
uniprot id: X5DX98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1404245:CGLY RS09580
gene id: 1404245:CGLY_RS09580
uniprot id: X5EAC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1404245:CGLY RS12595
gene id: 1404245:CGLY_RS12595
uniprot id: X5DP33
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1404245:CGLY RS05460
gene id: 1404245:CGLY_RS05460
uniprot id: X5DQH2
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS15160
gene id: 1404245:CGLY_RS15160
uniprot id: X5DQE0
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS02875
gene id: 1404245:CGLY_RS02875
uniprot id: X5DNZ2
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1404245:CGLY RS10030
gene id: 1404245:CGLY_RS10030
uniprot id: X5ECV1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1404245:CGLY RS03175
gene id: 1404245:CGLY_RS03175
uniprot id: X5E6L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1404245:CGLY RS03030
gene id: 1404245:CGLY_RS03030
uniprot id: X5E8P9
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS04535
gene id: 1404245:CGLY_RS04535
uniprot id: X5DJT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1404245:CGLY RS08385
gene id: 1404245:CGLY_RS08385
uniprot id: X5E9K4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1404245:CGLY RS08815
gene id: 1404245:CGLY_RS08815
uniprot id: X5EC57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1404245:CGLY RS10385
gene id: 1404245:CGLY_RS10385
uniprot id: X5ED04
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1404245:CGLY RS06765
gene id: 1404245:CGLY_RS06765
uniprot id: X5EB09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1404245:CGLY RS13120
gene id: 1404245:CGLY_RS13120
uniprot id: X5ECA6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1404245:CGLY RS05895
gene id: 1404245:CGLY_RS05895
uniprot id: X5EAE2
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS10305
gene id: 1404245:CGLY_RS10305
uniprot id: X5EAR0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1404245:CGLY RS03335
gene id: 1404245:CGLY_RS03335
uniprot id: X5DR25
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS02010
gene id: 1404245:CGLY_RS02010
uniprot id: X5E873
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1404245:CGLY RS05965
gene id: 1404245:CGLY_RS05965
uniprot id: X5E866
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1404245:CGLY RS05200
gene id: 1404245:CGLY_RS05200
uniprot id: X5EA05
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1404245:CGLY RS15020
gene id: 1404245:CGLY_RS15020
uniprot id: X5EDE7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1404245:CGLY RS04175
gene id: 1404245:CGLY_RS04175
uniprot id: X5E7A6
names: Similarity
messages: Belongs to the peptidase C1 family.

1404245:CGLY RS02665
gene id: 1404245:CGLY_RS02665
uniprot id: X5DQP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS02570
gene id: 1404245:CGLY_RS02570
uniprot id: X5DIS3
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS10250
gene id: 1404245:CGLY_RS10250
uniprot id: X5DT52
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1404245:CGLY RS06900
gene id: 1404245:CGLY_RS06900
uniprot id: X5DL59
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1404245:CGLY RS13320
gene id: 1404245:CGLY_RS13320
uniprot id: X5DUV2
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1404245:CGLY RS11775
gene id: 1404245:CGLY_RS11775
uniprot id: X5DW14
names: Similarity
messages: Belongs to the peptidase M1 family.

1404245:CGLY RS05625
gene id: 1404245:CGLY_RS05625
uniprot id: X5EA79
names: Similarity
messages: Belongs to the universal stress protein A family.

1404245:CGLY RS01455
gene id: 1404245:CGLY_RS01455
uniprot id: X5DI66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1404245:CGLY RS09150
gene id: 1404245:CGLY_RS09150
uniprot id: X5EA41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1404245:CGLY RS04675
gene id: 1404245:CGLY_RS04675
uniprot id: X5E9R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS05205
gene id: 1404245:CGLY_RS05205
uniprot id: X5DS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS04005
gene id: 1404245:CGLY_RS04005
uniprot id: X5DRF7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1404245:CGLY RS14150
gene id: 1404245:CGLY_RS14150
uniprot id: X5DVB2
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS11570
gene id: 1404245:CGLY_RS11570
uniprot id: X5DNL2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1404245:CGLY RS08060
gene id: 1404245:CGLY_RS08060
uniprot id: X5EBM7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1404245:CGLY RS06855
gene id: 1404245:CGLY_RS06855
uniprot id: X5DRD1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1404245:CGLY RS02200
gene id: 1404245:CGLY_RS02200
uniprot id: X5DIL4
names: Similarity
messages: Belongs to the CFA/CMAS family.

1404245:CGLY RS02495
gene id: 1404245:CGLY_RS02495
uniprot id: X5DIR0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1404245:CGLY RS08715
gene id: 1404245:CGLY_RS08715
uniprot id: X5EC33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1404245:CGLY RS04740
gene id: 1404245:CGLY_RS04740
uniprot id: X5DQ31
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1404245:CGLY RS04895
gene id: 1404245:CGLY_RS04895
uniprot id: X5DQ55
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1404245:CGLY RS05270
gene id: 1404245:CGLY_RS05270
uniprot id: X5E7S9
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS11190
gene id: 1404245:CGLY_RS11190
uniprot id: X5DVI0
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1404245:CGLY RS07675
gene id: 1404245:CGLY_RS07675
uniprot id: X5DRQ3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1404245:CGLY RS11730
gene id: 1404245:CGLY_RS11730
uniprot id: X5EBL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1404245:CGLY RS05175
gene id: 1404245:CGLY_RS05175
uniprot id: X5DS44
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1404245:CGLY RS07775
gene id: 1404245:CGLY_RS07775
uniprot id: X5DRS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1404245:CGLY RS09935
gene id: 1404245:CGLY_RS09935
uniprot id: X5DUU4
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1404245:CGLY RS06675
gene id: 1404245:CGLY_RS06675
uniprot id: X5DL03
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1404245:CGLY RS06750
gene id: 1404245:CGLY_RS06750
uniprot id: X5DL40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1404245:CGLY RS13160
gene id: 1404245:CGLY_RS13160
uniprot id: X5DWP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1404245:CGLY RS08375
gene id: 1404245:CGLY_RS08375
uniprot id: X5DLW1
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1404245:CGLY RS15135
gene id: 1404245:CGLY_RS15135
uniprot id: X5DQD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1404245:CGLY RS14175
gene id: 1404245:CGLY_RS14175
uniprot id: X5DVB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS03975
gene id: 1404245:CGLY_RS03975
uniprot id: X5E9B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1404245:CGLY RS04000
gene id: 1404245:CGLY_RS04000
uniprot id: X5E9C1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1404245:CGLY RS05885
gene id: 1404245:CGLY_RS05885
uniprot id: X5DQR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1404245:CGLY RS01615
gene id: 1404245:CGLY_RS01615
uniprot id: X5E7Y8
names: Similarity
messages: Belongs to the TPP enzyme family.

1404245:CGLY RS16170
gene id: 1404245:CGLY_RS16170
uniprot id: X5EE04
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1404245:CGLY RS04240
gene id: 1404245:CGLY_RS04240
uniprot id: X5DJP3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1404245:CGLY RS06285
gene id: 1404245:CGLY_RS06285
uniprot id: X5DR05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1404245:CGLY RS01945
gene id: 1404245:CGLY_RS01945
uniprot id: X5DQB3
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS05620
gene id: 1404245:CGLY_RS05620
uniprot id: X5E7Z6
names: Similarity
messages: Belongs to the universal stress protein A family.

1404245:CGLY RS03340
gene id: 1404245:CGLY_RS03340
uniprot id: X5DJ55
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1404245:CGLY RS09950
gene id: 1404245:CGLY_RS09950
uniprot id: X5EAI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1404245:CGLY RS03995
gene id: 1404245:CGLY_RS03995
uniprot id: X5E753
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1404245:CGLY RS10270
gene id: 1404245:CGLY_RS10270
uniprot id: X5DMW8
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1404245:CGLY RS05065
gene id: 1404245:CGLY_RS05065
uniprot id: X5E9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

1404245:CGLY RS12895
gene id: 1404245:CGLY_RS12895
uniprot id: X5DWK4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1404245:CGLY RS14310
gene id: 1404245:CGLY_RS14310
uniprot id: X5EF99
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1404245:CGLY RS13895
gene id: 1404245:CGLY_RS13895
uniprot id: X5ECS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1404245:CGLY RS04430
gene id: 1404245:CGLY_RS04430
uniprot id: X5DRR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1404245:CGLY RS12520
gene id: 1404245:CGLY_RS12520
uniprot id: X5DP18
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1404245:CGLY RS03875
gene id: 1404245:CGLY_RS03875
uniprot id: X5E988
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1404245:CGLY RS04865
gene id: 1404245:CGLY_RS04865
uniprot id: X5DJY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS01580
gene id: 1404245:CGLY_RS01580
uniprot id: X5DNB0
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1404245:CGLY RS14610
gene id: 1404245:CGLY_RS14610
uniprot id: X5DVJ9
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS09755
gene id: 1404245:CGLY_RS09755
uniprot id: X5EAF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1404245:CGLY RS08485
gene id: 1404245:CGLY_RS08485
uniprot id: X5E9M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1404245:CGLY RS08550
gene id: 1404245:CGLY_RS08550
uniprot id: X5DLZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1404245:CGLY RS12930
gene id: 1404245:CGLY_RS12930
uniprot id: X5DUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1404245:CGLY RS03395
gene id: 1404245:CGLY_RS03395
uniprot id: X5E6P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1404245:CGLY RS16965
gene id: 1404245:CGLY_RS16965
uniprot id: X5DQR9
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS09855
gene id: 1404245:CGLY_RS09855
uniprot id: X5EAH1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1404245:CGLY RS01470
gene id: 1404245:CGLY_RS01470
uniprot id: X5E7V0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1404245:CGLY RS11965
gene id: 1404245:CGLY_RS11965
uniprot id: X5DU80
names: Similarity
messages: Belongs to the asp23 family.

1404245:CGLY RS05735
gene id: 1404245:CGLY_RS05735
uniprot id: X5DKE8
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS12845
gene id: 1404245:CGLY_RS12845
uniprot id: X5DWJ5
names: Subcellular Location Annotation
messages: Cell membrane

1404245:CGLY RS11510
gene id: 1404245:CGLY_RS11510
uniprot id: X5EDQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1404245:CGLY RS00870
gene id: 1404245:CGLY_RS00870
uniprot id: X5E574
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS04805
gene id: 1404245:CGLY_RS04805
uniprot id: X5E9S9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1404245:CGLY RS03455
gene id: 1404245:CGLY_RS03455
uniprot id: X5DR43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1404245:CGLY RS13070
gene id: 1404245:CGLY_RS13070
uniprot id: X5DUQ9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1404245:CGLY RS05680
gene id: 1404245:CGLY_RS05680
uniprot id: X5DSD6
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS15500
gene id: 1404245:CGLY_RS15500
uniprot id: X5EFW5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1404245:CGLY RS08270
gene id: 1404245:CGLY_RS08270
uniprot id: X5EBS2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1404245:CGLY RS05105
gene id: 1404245:CGLY_RS05105
uniprot id: X5DQ90
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1404245:CGLY RS11575
gene id: 1404245:CGLY_RS11575
uniprot id: X5DU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1404245:CGLY RS02055
gene id: 1404245:CGLY_RS02055
uniprot id: X5E5Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS09345
gene id: 1404245:CGLY_RS09345
uniprot id: X5EA92
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1404245:CGLY RS15670
gene id: 1404245:CGLY_RS15670
uniprot id: X5EFZ3
names: Similarity
messages: Belongs to the peptidase M13 family.

1404245:CGLY RS02785
gene id: 1404245:CGLY_RS02785
uniprot id: X5E8K6
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS12430
gene id: 1404245:CGLY_RS12430
uniprot id: X5EBY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1404245:CGLY RS09595
gene id: 1404245:CGLY_RS09595
uniprot id: X5DML1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1404245:CGLY RS09605
gene id: 1404245:CGLY_RS09605
uniprot id: X5EAD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1404245:CGLY RS06200
gene id: 1404245:CGLY_RS06200
uniprot id: X5DSM4
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1404245:CGLY RS03820
gene id: 1404245:CGLY_RS03820
uniprot id: X5E707
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1404245:CGLY RS11820
gene id: 1404245:CGLY_RS11820
uniprot id: X5EDZ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1404245:CGLY RS06475
gene id: 1404245:CGLY_RS06475
uniprot id: X5DKV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1404245:CGLY RS05880
gene id: 1404245:CGLY_RS05880
uniprot id: X5DKH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS11620
gene id: 1404245:CGLY_RS11620
uniprot id: X5DNM3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1404245:CGLY RS16060
gene id: 1404245:CGLY_RS16060
uniprot id: X5DWB8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1404245:CGLY RS00010
gene id: 1404245:CGLY_RS00010
uniprot id: X5DP73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1404245:CGLY RS06150
gene id: 1404245:CGLY_RS06150
uniprot id: X5DSL4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1404245:CGLY RS14705
gene id: 1404245:CGLY_RS14705
uniprot id: X5DXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS12310
gene id: 1404245:CGLY_RS12310
uniprot id: X5DNY5
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1404245:CGLY RS05955
gene id: 1404245:CGLY_RS05955
uniprot id: X5DKJ4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1404245:CGLY RS01390
gene id: 1404245:CGLY_RS01390
uniprot id: X5E5I4
names: Similarity
messages: Belongs to the creatininase superfamily.

1404245:CGLY RS04255
gene id: 1404245:CGLY_RS04255
uniprot id: X5E9J4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1404245:CGLY RS02625
gene id: 1404245:CGLY_RS02625
uniprot id: X5DNT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS08475
gene id: 1404245:CGLY_RS08475
uniprot id: X5DLY3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1404245:CGLY RS03755
gene id: 1404245:CGLY_RS03755
uniprot id: X5DR99
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1404245:CGLY RS03895
gene id: 1404245:CGLY_RS03895
uniprot id: X5E727
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1404245:CGLY RS10580
gene id: 1404245:CGLY_RS10580
uniprot id: X5ED32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1404245:CGLY RS08545
gene id: 1404245:CGLY_RS08545
uniprot id: X5DTY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1404245:CGLY RS02630
gene id: 1404245:CGLY_RS02630
uniprot id: X5E6A0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1404245:CGLY RS14670
gene id: 1404245:CGLY_RS14670
uniprot id: X5EFI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1404245:CGLY RS08680
gene id: 1404245:CGLY_RS08680
uniprot id: X5DSA0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1404245:CGLY RS15990
gene id: 1404245:CGLY_RS15990
uniprot id: X5EDW5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1404245:CGLY RS14045
gene id: 1404245:CGLY_RS14045
uniprot id: X5DPT4
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

1404245:CGLY RS09500
gene id: 1404245:CGLY_RS09500
uniprot id: X5DSS0
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1404245:CGLY RS03440
gene id: 1404245:CGLY_RS03440
uniprot id: X5DPB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1404245:CGLY RS00990
gene id: 1404245:CGLY_RS00990
uniprot id: X5DMX3
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1404245:CGLY RS00340
gene id: 1404245:CGLY_RS00340
uniprot id: X5DHK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1404245:CGLY RS07595
gene id: 1404245:CGLY_RS07595
uniprot id: X5DLH2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1404245:CGLY RS07745
gene id: 1404245:CGLY_RS07745
uniprot id: X5DLJ9
names: Similarity
messages: Belongs to the PrpD family.

1404245:CGLY RS10880
gene id: 1404245:CGLY_RS10880
uniprot id: X5ED99
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1404245:CGLY RS13850
gene id: 1404245:CGLY_RS13850
uniprot id: X5EEZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1404245:CGLY RS14645
gene id: 1404245:CGLY_RS14645
uniprot id: X5EFH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1404245:CGLY RS14070
gene id: 1404245:CGLY_RS14070
uniprot id: X5DPT9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1404245:CGLY RS06740
gene id: 1404245:CGLY_RS06740
uniprot id: X5EB05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1404245:CGLY RS02080
gene id: 1404245:CGLY_RS02080
uniprot id: X5E600
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1404245:CGLY RS10350
gene id: 1404245:CGLY_RS10350
uniprot id: X5DT73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1404245:CGLY RS15490
gene id: 1404245:CGLY_RS15490
uniprot id: X5DVZ8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1404245:CGLY RS03880
gene id: 1404245:CGLY_RS03880
uniprot id: X5DRC7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1404245:CGLY RS01560
gene id: 1404245:CGLY_RS01560
uniprot id: X5E5M9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1404245:CGLY RS16015
gene id: 1404245:CGLY_RS16015
uniprot id: X5EDW9
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1404245:CGLY RS04900
gene id: 1404245:CGLY_RS04900
uniprot id: X5E7L5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1404245:CGLY RS06720
gene id: 1404245:CGLY_RS06720
uniprot id: X5DT16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1404245:CGLY RS13045
gene id: 1404245:CGLY_RS13045
uniprot id: X5DUQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS04170
gene id: 1404245:CGLY_RS04170
uniprot id: X5DPV3
names: Similarity
messages: Belongs to the peptidase C1 family.

1404245:CGLY RS12605
gene id: 1404245:CGLY_RS12605
uniprot id: X5EC17
names: Subcellular Location Annotation
messages: Membrane

1404245:CGLY RS01640
gene id: 1404245:CGLY_RS01640
uniprot id: X5E809
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1404245:CGLY RS13430
gene id: 1404245:CGLY_RS13430
uniprot id: X5EEN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Siderophore-Fe(3+) uptake transporter (SIUT) (TC 3.A.1.21) family.
messages: Cell inner membrane
messages: Forms a heterodimer with IrtB.
messages: Membrane

1404245:CGLY RS13965
gene id: 1404245:CGLY_RS13965
uniprot id: X5DV79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1404245:CGLY RS07660
gene id: 1404245:CGLY_RS07660
uniprot id: X5EBG0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1404245:CGLY RS04055
gene id: 1404245:CGLY_RS04055
uniprot id: X5E9D5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1404245:CGLY RS11780
gene id: 1404245:CGLY_RS11780
uniprot id: X5DNR3
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1404245:CGLY RS15200
gene id: 1404245:CGLY_RS15200
uniprot id: X5EFR8
names: Similarity
messages: Belongs to the AccD/PCCB family.

1404245:CGLY RS05935
gene id: 1404245:CGLY_RS05935
uniprot id: X5DQS8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1404245:CGLY RS08600
gene id: 1404245:CGLY_RS08600
uniprot id: X5DM05
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1404245:CGLY RS15150
gene id: 1404245:CGLY_RS15150
uniprot id: X5EFR0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS06950
gene id: 1404245:CGLY_RS06950
uniprot id: X5DL63
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1404245:CGLY RS07840
gene id: 1404245:CGLY_RS07840
uniprot id: X5DTL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1404245:CGLY RS09590
gene id: 1404245:CGLY_RS09590
uniprot id: X5DUM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1404245:CGLY RS08260
gene id: 1404245:CGLY_RS08260
uniprot id: X5DS21
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1404245:CGLY RS08865
gene id: 1404245:CGLY_RS08865
uniprot id: X5EC72
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1404245:CGLY RS11690
gene id: 1404245:CGLY_RS11690
uniprot id: X5DVX7
names: Subcellular Location Annotation
messages: Membrane