1376:AWM73 RS02140
gene id: 1376:AWM73_RS02140
uniprot id: A0A0X8FF61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1376:AWM73 RS04650
gene id: 1376:AWM73_RS04650
uniprot id: A0A7T2RPQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1376:AWM73 RS05235
gene id: 1376:AWM73_RS05235
uniprot id: A0A0X8FG94
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1376:AWM73 RS04350
gene id: 1376:AWM73_RS04350
uniprot id: A0A120I9S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

1376:AWM73 RS05080
gene id: 1376:AWM73_RS05080
uniprot id: A0A0X8FG74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1376:AWM73 RS00975
gene id: 1376:AWM73_RS00975
uniprot id: A0A109RE60
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1376:AWM73 RS03615
gene id: 1376:AWM73_RS03615
uniprot id: A0A0X8FE25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1376:AWM73 RS02060
gene id: 1376:AWM73_RS02060
uniprot id: A0A0X8FF50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1376:AWM73 RS07710
gene id: 1376:AWM73_RS07710
uniprot id: A0A0X8FFI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1376:AWM73 RS02270
gene id: 1376:AWM73_RS02270
uniprot id: A0A0X8FDN1
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1376:AWM73 RS08075
gene id: 1376:AWM73_RS08075
uniprot id: A0A120I9Z6
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS06970
gene id: 1376:AWM73_RS06970
uniprot id: A0A0X8FF93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1376:AWM73 RS04180
gene id: 1376:AWM73_RS04180
uniprot id: A0A120I9R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1376:AWM73 RS06905
gene id: 1376:AWM73_RS06905
uniprot id: A0A0X8FF86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1376:AWM73 RS02830
gene id: 1376:AWM73_RS02830
uniprot id: A0A0X8FDU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1376:AWM73 RS02370
gene id: 1376:AWM73_RS02370
uniprot id: A0A120I9N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1376:AWM73 RS07515
gene id: 1376:AWM73_RS07515
uniprot id: A0A0X8FGX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1376:AWM73 RS02950
gene id: 1376:AWM73_RS02950
uniprot id: A0A0X8FE13
names: Similarity
messages: Belongs to the acylphosphatase family.

1376:AWM73 RS06695
gene id: 1376:AWM73_RS06695
uniprot id: A0A120I9W6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1376:AWM73 RS06825
gene id: 1376:AWM73_RS06825
uniprot id: A0A0X8FFL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1376:AWM73 RS04675
gene id: 1376:AWM73_RS04675
uniprot id: A0A109REC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1376:AWM73 RS08450
gene id: 1376:AWM73_RS08450
uniprot id: A0A109REY2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS00200
gene id: 1376:AWM73_RS00200
uniprot id: A0A0X8FCW1
names: Similarity
messages: Belongs to the ycf81 family.

1376:AWM73 RS02850
gene id: 1376:AWM73_RS02850
uniprot id: A0A109REI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1376:AWM73 RS03825
gene id: 1376:AWM73_RS03825
uniprot id: A0A0X8FE75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1376:AWM73 RS03605
gene id: 1376:AWM73_RS03605
uniprot id: A0A0X8FE30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1376:AWM73 RS07015
gene id: 1376:AWM73_RS07015
uniprot id: A0A0X8FFD7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1376:AWM73 RS01310
gene id: 1376:AWM73_RS01310
uniprot id: A0A0X8FDF5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1376:AWM73 RS05170
gene id: 1376:AWM73_RS05170
uniprot id: A0A109REU1
names: Similarity
messages: Belongs to the XFP family.

1376:AWM73 RS08840
gene id: 1376:AWM73_RS08840
uniprot id: A0A0X8FHF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1376:AWM73 RS05470
gene id: 1376:AWM73_RS05470
uniprot id: A0A0X8FER2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1376:AWM73 RS05780
gene id: 1376:AWM73_RS05780
uniprot id: A0A0X8FF30
names: Similarity
messages: Belongs to the EamA transporter family.

1376:AWM73 RS02500
gene id: 1376:AWM73_RS02500
uniprot id: A0A0X8FDS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1376:AWM73 RS03830
gene id: 1376:AWM73_RS03830
uniprot id: A0A0X8FE56
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1376:AWM73 RS01475
gene id: 1376:AWM73_RS01475
uniprot id: A0A0X8FDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1376:AWM73 RS02175
gene id: 1376:AWM73_RS02175
uniprot id: A0A0X8FDL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1376:AWM73 RS07355
gene id: 1376:AWM73_RS07355
uniprot id: A0A0X8FFF0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1376:AWM73 RS07925
gene id: 1376:AWM73_RS07925
uniprot id: A0A0X8FFP7
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS00995
gene id: 1376:AWM73_RS00995
uniprot id: A0A0X8FD64
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1376:AWM73 RS08550
gene id: 1376:AWM73_RS08550
uniprot id: A0A0X8FFY7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1376:AWM73 RS03690
gene id: 1376:AWM73_RS03690
uniprot id: A0A0X8FE35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1376:AWM73 RS07650
gene id: 1376:AWM73_RS07650
uniprot id: A0A0X8FFW3
names: Similarity
messages: Belongs to the UPF0246 family.

1376:AWM73 RS08465
gene id: 1376:AWM73_RS08465
uniprot id: A0A329NHX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1376:AWM73 RS04405
gene id: 1376:AWM73_RS04405
uniprot id: A0A0X8FED9
names: Similarity
messages: Belongs to the DHPS family.

1376:AWM73 RS01535
gene id: 1376:AWM73_RS01535
uniprot id: A0A0X8FDI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS04010
gene id: 1376:AWM73_RS04010
uniprot id: A0A7T2RPY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1376:AWM73 RS06725
gene id: 1376:AWM73_RS06725
uniprot id: A0A0X8FF76
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

1376:AWM73 RS01840
gene id: 1376:AWM73_RS01840
uniprot id: A0A0X8FDM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS06460
gene id: 1376:AWM73_RS06460
uniprot id: A0A109REN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS08765
gene id: 1376:AWM73_RS08765
uniprot id: A0A120IA08
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1376:AWM73 RS05480
gene id: 1376:AWM73_RS05480
uniprot id: A0A0X8FGC2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1376:AWM73 RS01430
gene id: 1376:AWM73_RS01430
uniprot id: A0A0X8FEW9
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS00910
gene id: 1376:AWM73_RS00910
uniprot id: A0A0X8FDB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1376:AWM73 RS04755
gene id: 1376:AWM73_RS04755
uniprot id: A0A7T2RP58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1376:AWM73 RS08645
gene id: 1376:AWM73_RS08645
uniprot id: A0A0X8FFU1
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS09020
gene id: 1376:AWM73_RS09020
uniprot id: A0A2I1L5Y8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1376:AWM73 RS02425
gene id: 1376:AWM73_RS02425
uniprot id: A0A0X8FDQ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1376:AWM73 RS02675
gene id: 1376:AWM73_RS02675
uniprot id: A0A109RE93
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1376:AWM73 RS02845
gene id: 1376:AWM73_RS02845
uniprot id: A0A120I9P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1376:AWM73 RS03560
gene id: 1376:AWM73_RS03560
uniprot id: A0A109RFR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1376:AWM73 RS04365
gene id: 1376:AWM73_RS04365
uniprot id: A0A0X8FEG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1376:AWM73 RS00150
gene id: 1376:AWM73_RS00150
uniprot id: A0A0X8FCW0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1376:AWM73 RS04320
gene id: 1376:AWM73_RS04320
uniprot id: A0A0X8FEC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS05410
gene id: 1376:AWM73_RS05410
uniprot id: A0A7T2RPP0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1376:AWM73 RS06050
gene id: 1376:AWM73_RS06050
uniprot id: A0A0X8FEY3
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS03135
gene id: 1376:AWM73_RS03135
uniprot id: A0A0X8FE03
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1376:AWM73 RS06025
gene id: 1376:AWM73_RS06025
uniprot id: A0A0X8FF58
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1376:AWM73 RS07245
gene id: 1376:AWM73_RS07245
uniprot id: A0A7T2RRJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS00735
gene id: 1376:AWM73_RS00735
uniprot id: A0A120I9J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1376:AWM73 RS03970
gene id: 1376:AWM73_RS03970
uniprot id: A0A0X8FE98
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS05315
gene id: 1376:AWM73_RS05315
uniprot id: A0A0X8FGA3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1376:AWM73 RS01700
gene id: 1376:AWM73_RS01700
uniprot id: A0A0X8FDF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1376:AWM73 RS03695
gene id: 1376:AWM73_RS03695
uniprot id: A0A109REC7
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1376:AWM73 RS08095
gene id: 1376:AWM73_RS08095
uniprot id: A0A0X8FFW1
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS02235
gene id: 1376:AWM73_RS02235
uniprot id: A0A109RFK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1376:AWM73 RS04505
gene id: 1376:AWM73_RS04505
uniprot id: A0A7T2RPZ3
names: Similarity
messages: Belongs to the fructosamine kinase family.

1376:AWM73 RS00255
gene id: 1376:AWM73_RS00255
uniprot id: A0A109RE90
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1376:AWM73 RS04940
gene id: 1376:AWM73_RS04940
uniprot id: A0A329NLX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1376:AWM73 RS03160
gene id: 1376:AWM73_RS03160
uniprot id: A0A109REB2
names: Similarity
messages: Belongs to the CvfB family.

1376:AWM73 RS05060
gene id: 1376:AWM73_RS05060
uniprot id: A0A0X8FEZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1376:AWM73 RS06830
gene id: 1376:AWM73_RS06830
uniprot id: A0A0X8FF74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1376:AWM73 RS01295
gene id: 1376:AWM73_RS01295
uniprot id: A0A109RFI8
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1376:AWM73 RS05505
gene id: 1376:AWM73_RS05505
uniprot id: A0A7T2RNW7
names: Similarity
messages: Belongs to the asp23 family.

1376:AWM73 RS01015
gene id: 1376:AWM73_RS01015
uniprot id: A0A0X8FD67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1376:AWM73 RS08360
gene id: 1376:AWM73_RS08360
uniprot id: A0A0X8FH95
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS07085
gene id: 1376:AWM73_RS07085
uniprot id: A0A120I9X6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS05855
gene id: 1376:AWM73_RS05855
uniprot id: A0A0X8FEX0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1376:AWM73 RS05645
gene id: 1376:AWM73_RS05645
uniprot id: A0A120I9U2
names: Similarity
messages: Belongs to the thioredoxin family.

1376:AWM73 RS04925
gene id: 1376:AWM73_RS04925
uniprot id: A0A7T2RPE1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1376:AWM73 RS05715
gene id: 1376:AWM73_RS05715
uniprot id: A0A109RF69
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1376:AWM73 RS02685
gene id: 1376:AWM73_RS02685
uniprot id: A0A0X8FFD8
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1376:AWM73 RS02825
gene id: 1376:AWM73_RS02825
uniprot id: A0A0X8FE80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS06180
gene id: 1376:AWM73_RS06180
uniprot id: A0A0X8FF80
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1376:AWM73 RS03640
gene id: 1376:AWM73_RS03640
uniprot id: A0A120I9Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1376:AWM73 RS04575
gene id: 1376:AWM73_RS04575
uniprot id: A0A7T2RPR1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1376:AWM73 RS01545
gene id: 1376:AWM73_RS01545
uniprot id: A0A0X8FDD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1376:AWM73 RS02450
gene id: 1376:AWM73_RS02450
uniprot id: A0A109REA5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1376:AWM73 RS06900
gene id: 1376:AWM73_RS06900
uniprot id: A0A0X8FFM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1376:AWM73 RS00130
gene id: 1376:AWM73_RS00130
uniprot id: A0A0X8FCV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Cell membrane
messages: Probably a homodimer.

1376:AWM73 RS06885
gene id: 1376:AWM73_RS06885
uniprot id: A0A0X8FF75
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1376:AWM73 RS04570
gene id: 1376:AWM73_RS04570
uniprot id: A0A0X8FEF8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1376:AWM73 RS02355
gene id: 1376:AWM73_RS02355
uniprot id: A0A0X8FDP0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1376:AWM73 RS06085
gene id: 1376:AWM73_RS06085
uniprot id: A0A0X8FF27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1376:AWM73 RS04565
gene id: 1376:AWM73_RS04565
uniprot id: A0A0X8FET2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS06965
gene id: 1376:AWM73_RS06965
uniprot id: A0A0X8FFA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1376:AWM73 RS08225
gene id: 1376:AWM73_RS08225
uniprot id: A0A109RG68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS06850
gene id: 1376:AWM73_RS06850
uniprot id: A0A120I9W9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1376:AWM73 RS05760
gene id: 1376:AWM73_RS05760
uniprot id: A0A0X8FEW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS03625
gene id: 1376:AWM73_RS03625
uniprot id: A0A0X8FFP1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS07205
gene id: 1376:AWM73_RS07205
uniprot id: A0A0X8FFA9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1376:AWM73 RS04660
gene id: 1376:AWM73_RS04660
uniprot id: A0A120I9S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1376:AWM73 RS07440
gene id: 1376:AWM73_RS07440
uniprot id: A0A120I9X9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1376:AWM73 RS03540
gene id: 1376:AWM73_RS03540
uniprot id: A0A109REC4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS08625
gene id: 1376:AWM73_RS08625
uniprot id: A0A0X8FFZ6
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS05185
gene id: 1376:AWM73_RS05185
uniprot id: A0A0X8FER5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS06075
gene id: 1376:AWM73_RS06075
uniprot id: A0A120I9V5
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS07745
gene id: 1376:AWM73_RS07745
uniprot id: A0A109RET1
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1376:AWM73 RS06185
gene id: 1376:AWM73_RS06185
uniprot id: A0A0X8FEZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS03980
gene id: 1376:AWM73_RS03980
uniprot id: A0A0X8FEG5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1376:AWM73 RS02515
gene id: 1376:AWM73_RS02515
uniprot id: A0A0X8FDR0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1376:AWM73 RS07760
gene id: 1376:AWM73_RS07760
uniprot id: A0A7T2RRM2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1376:AWM73 RS00695
gene id: 1376:AWM73_RS00695
uniprot id: A0A0X8FD92
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1376:AWM73 RS06240
gene id: 1376:AWM73_RS06240
uniprot id: A0A109RFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS07865
gene id: 1376:AWM73_RS07865
uniprot id: A0A0X8FFJ7
names: Similarity
messages: Belongs to the peptidase C56 family.

1376:AWM73 RS00800
gene id: 1376:AWM73_RS00800
uniprot id: A0A109RE12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1376:AWM73 RS01850
gene id: 1376:AWM73_RS01850
uniprot id: A0A0X8FDH3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1376:AWM73 RS01895
gene id: 1376:AWM73_RS01895
uniprot id: A0A0X8FF29
names: Similarity
messages: Belongs to the thioredoxin family.

1376:AWM73 RS05955
gene id: 1376:AWM73_RS05955
uniprot id: A0A0X8FFB2
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS04835
gene id: 1376:AWM73_RS04835
uniprot id: A0A120I9T1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS06870
gene id: 1376:AWM73_RS06870
uniprot id: A0A0X8FF88
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1376:AWM73 RS00950
gene id: 1376:AWM73_RS00950
uniprot id: A0A0X8FD62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS01225
gene id: 1376:AWM73_RS01225
uniprot id: A0A109RDZ0
names: Similarity
messages: Belongs to the carbamate kinase family.

1376:AWM73 RS04145
gene id: 1376:AWM73_RS04145
uniprot id: A0A0X8FEC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1376:AWM73 RS01970
gene id: 1376:AWM73_RS01970
uniprot id: A0A109RE59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS05820
gene id: 1376:AWM73_RS05820
uniprot id: A0A120I9U7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gtf3 glucosyltransferase family.
messages: Dimerizes via the C-terminus; dimerization is required for tetramer formation. Binds protein substrate via an exposed loop in the N-terminus.
messages: Homotetramer; a dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the second step in glycosylation by transferring a sugar from a UDP-activated sugar to the terminal GlcNAc moiety of the 3-O-(N-acetyl-alpha-D-glucosaminyl)-L-seryl-[protein] resulting from the first glycosylation step.

1376:AWM73 RS02265
gene id: 1376:AWM73_RS02265
uniprot id: A0A0X8FDP2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1376:AWM73 RS04625
gene id: 1376:AWM73_RS04625
uniprot id: A0A0X8FEG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1376:AWM73 RS02840
gene id: 1376:AWM73_RS02840
uniprot id: A0A0X8FFF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

1376:AWM73 RS06880
gene id: 1376:AWM73_RS06880
uniprot id: A0A0X8FFF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1376:AWM73 RS04550
gene id: 1376:AWM73_RS04550
uniprot id: A0A0X8FEF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1376:AWM73 RS05615
gene id: 1376:AWM73_RS05615
uniprot id: A0A0X8FEU8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1376:AWM73 RS02925
gene id: 1376:AWM73_RS02925
uniprot id: A0A0X8FFH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1376:AWM73 RS06980
gene id: 1376:AWM73_RS06980
uniprot id: A0A0X8FF96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1376:AWM73 RS07625
gene id: 1376:AWM73_RS07625
uniprot id: A0A0X8FFI4
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1376:AWM73 RS08980
gene id: 1376:AWM73_RS08980
uniprot id: A0A0X8FFY0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS01835
gene id: 1376:AWM73_RS01835
uniprot id: A0A120I9L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS08320
gene id: 1376:AWM73_RS08320
uniprot id: A0A0X8FFR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1376:AWM73 RS07665
gene id: 1376:AWM73_RS07665
uniprot id: A0A0X8FGZ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1376:AWM73 RS05180
gene id: 1376:AWM73_RS05180
uniprot id: A0A109REE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS06760
gene id: 1376:AWM73_RS06760
uniprot id: A0A109REY5
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

1376:AWM73 RS05405
gene id: 1376:AWM73_RS05405
uniprot id: A0A109REU7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1376:AWM73 RS04530
gene id: 1376:AWM73_RS04530
uniprot id: A0A0X8FEI1
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS05075
gene id: 1376:AWM73_RS05075
uniprot id: A0A109REM9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1376:AWM73 RS02475
gene id: 1376:AWM73_RS02475
uniprot id: A0A0X8FDV1
names: Similarity
messages: Belongs to the UPF0758 family.

1376:AWM73 RS07335
gene id: 1376:AWM73_RS07335
uniprot id: A0A120I9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1376:AWM73 RS08540
gene id: 1376:AWM73_RS08540
uniprot id: A0A120IA04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1376:AWM73 RS00905
gene id: 1376:AWM73_RS00905
uniprot id: A0A120I9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1376:AWM73 RS07190
gene id: 1376:AWM73_RS07190
uniprot id: A0A0X8FFC8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1376:AWM73 RS06395
gene id: 1376:AWM73_RS06395
uniprot id: A0A109REQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1376:AWM73 RS06860
gene id: 1376:AWM73_RS06860
uniprot id: A0A120I9X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1376:AWM73 RS02220
gene id: 1376:AWM73_RS02220
uniprot id: A0A109RE97
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS03315
gene id: 1376:AWM73_RS03315
uniprot id: A0A0X8FED1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS02560
gene id: 1376:AWM73_RS02560
uniprot id: A0A0X8FDW7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1376:AWM73 RS00990
gene id: 1376:AWM73_RS00990
uniprot id: A0A0X8FDB6
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

1376:AWM73 RS05165
gene id: 1376:AWM73_RS05165
uniprot id: A0A120I9T2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1376:AWM73 RS03150
gene id: 1376:AWM73_RS03150
uniprot id: A0A0X8FDY6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS01525
gene id: 1376:AWM73_RS01525
uniprot id: A0A109RFJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

1376:AWM73 RS06780
gene id: 1376:AWM73_RS06780
uniprot id: A0A109RG25
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1376:AWM73 RS00495
gene id: 1376:AWM73_RS00495
uniprot id: A0A109REA0
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS03760
gene id: 1376:AWM73_RS03760
uniprot id: A0A0X8FEH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS04135
gene id: 1376:AWM73_RS04135
uniprot id: A0A0X8FEI4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS04560
gene id: 1376:AWM73_RS04560
uniprot id: A0A0X8FEF5
names: Similarity
messages: Belongs to the universal stress protein A family.

1376:AWM73 RS08060
gene id: 1376:AWM73_RS08060
uniprot id: A0A120I9Z4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1376:AWM73 RS07115
gene id: 1376:AWM73_RS07115
uniprot id: A0A0X8FFA2
names: Similarity
messages: Belongs to the barstar family.

1376:AWM73 RS07005
gene id: 1376:AWM73_RS07005
uniprot id: A0A109RG32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1376:AWM73 RS02365
gene id: 1376:AWM73_RS02365
uniprot id: A0A0X8FF94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1376:AWM73 RS05875
gene id: 1376:AWM73_RS05875
uniprot id: A0A7T2VU03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1376:AWM73 RS04630
gene id: 1376:AWM73_RS04630
uniprot id: A0A0X8FEI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1376:AWM73 RS02705
gene id: 1376:AWM73_RS02705
uniprot id: A0A109RFL9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1376:AWM73 RS04590
gene id: 1376:AWM73_RS04590
uniprot id: A0A120I9S6
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1376:AWM73 RS02550
gene id: 1376:AWM73_RS02550
uniprot id: A0A120I9N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1376:AWM73 RS02045
gene id: 1376:AWM73_RS02045
uniprot id: A0A0X8FDY5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1376:AWM73 RS03545
gene id: 1376:AWM73_RS03545
uniprot id: A0A7T2RQ45
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1376:AWM73 RS03285
gene id: 1376:AWM73_RS03285
uniprot id: A0A0X8FE51
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1376:AWM73 RS04970
gene id: 1376:AWM73_RS04970
uniprot id: A0A0X8FEK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1376:AWM73 RS08430
gene id: 1376:AWM73_RS08430
uniprot id: A0A7T2RR20
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1376:AWM73 RS05565
gene id: 1376:AWM73_RS05565
uniprot id: A0A120I9U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1376:AWM73 RS07490
gene id: 1376:AWM73_RS07490
uniprot id: A0A0X8FFG3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1376:AWM73 RS03725
gene id: 1376:AWM73_RS03725
uniprot id: A0A0X8FE97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

1376:AWM73 RS01730
gene id: 1376:AWM73_RS01730
uniprot id: A0A0X8FDF9
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS07450
gene id: 1376:AWM73_RS07450
uniprot id: A0A109REU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1376:AWM73 RS00615
gene id: 1376:AWM73_RS00615
uniprot id: A0A0X8FD83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1376:AWM73 RS03595
gene id: 1376:AWM73_RS03595
uniprot id: A0A0X8FE21
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS04100
gene id: 1376:AWM73_RS04100
uniprot id: A0A120I9R6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

1376:AWM73 RS03590
gene id: 1376:AWM73_RS03590
uniprot id: A0A0X8FE96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1376:AWM73 RS00095
gene id: 1376:AWM73_RS00095
uniprot id: A0A109RFC4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1376:AWM73 RS08390
gene id: 1376:AWM73_RS08390
uniprot id: A0A0X8FFR8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1376:AWM73 RS09015
gene id: 1376:AWM73_RS09015
uniprot id: A0A178HEU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1376:AWM73 RS05610
gene id: 1376:AWM73_RS05610
uniprot id: A0A0X8FES7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1376:AWM73 RS02920
gene id: 1376:AWM73_RS02920
uniprot id: A0A109RET7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1376:AWM73 RS01350
gene id: 1376:AWM73_RS01350
uniprot id: A0A109REA1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1376:AWM73 RS00120
gene id: 1376:AWM73_RS00120
uniprot id: A0A0X8FCV7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1376:AWM73 RS01785
gene id: 1376:AWM73_RS01785
uniprot id: A0A0X8FDG1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1376:AWM73 RS08000
gene id: 1376:AWM73_RS08000
uniprot id: A0A109RG62
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1376:AWM73 RS07525
gene id: 1376:AWM73_RS07525
uniprot id: A0A109RER7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1376:AWM73 RS05740
gene id: 1376:AWM73_RS05740
uniprot id: A0A109REG9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1376:AWM73 RS08690
gene id: 1376:AWM73_RS08690
uniprot id: A0A109RG96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1376:AWM73 RS03500
gene id: 1376:AWM73_RS03500
uniprot id: A0A7T2RPV3
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1376:AWM73 RS02655
gene id: 1376:AWM73_RS02655
uniprot id: A0A0X8FDU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

1376:AWM73 RS07975
gene id: 1376:AWM73_RS07975
uniprot id: A0A109RF34
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1376:AWM73 RS03610
gene id: 1376:AWM73_RS03610
uniprot id: A0A0X8FEF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1376:AWM73 RS04635
gene id: 1376:AWM73_RS04635
uniprot id: A0A0X8FEG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1376:AWM73 RS07575
gene id: 1376:AWM73_RS07575
uniprot id: A0A0X8FFV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1376:AWM73 RS06950
gene id: 1376:AWM73_RS06950
uniprot id: A0A0X8FFA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1376:AWM73 RS05190
gene id: 1376:AWM73_RS05190
uniprot id: A0A0X8FEP7
names: Similarity
messages: Belongs to the peptidase M13 family.

1376:AWM73 RS02935
gene id: 1376:AWM73_RS02935
uniprot id: A0A109RE82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1376:AWM73 RS06795
gene id: 1376:AWM73_RS06795
uniprot id: A0A7T2VTI5
names: Subcellular Location Annotation
messages: cell wall

1376:AWM73 RS01245
gene id: 1376:AWM73_RS01245
uniprot id: A0A7T2RQR2
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1376:AWM73 RS02075
gene id: 1376:AWM73_RS02075
uniprot id: A0A120I9M1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS02330
gene id: 1376:AWM73_RS02330
uniprot id: A0A7T2VT03
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1376:AWM73 RS01795
gene id: 1376:AWM73_RS01795
uniprot id: A0A0X8FDH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1376:AWM73 RS06500
gene id: 1376:AWM73_RS06500
uniprot id: A0A0X8FFB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1376:AWM73 RS02100
gene id: 1376:AWM73_RS02100
uniprot id: A0A0X8FDK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1376:AWM73 RS08820
gene id: 1376:AWM73_RS08820
uniprot id: A0A0X8FGA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1376:AWM73 RS06805
gene id: 1376:AWM73_RS06805
uniprot id: A0A0X8FFE8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1376:AWM73 RS07500
gene id: 1376:AWM73_RS07500
uniprot id: A0A0X8FFU4
names: Similarity
messages: Belongs to the KdgT transporter family.

1376:AWM73 RS04855
gene id: 1376:AWM73_RS04855
uniprot id: A0A0X8FEK2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1376:AWM73 RS07350
gene id: 1376:AWM73_RS07350
uniprot id: A0A0X8FFH2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1376:AWM73 RS03740
gene id: 1376:AWM73_RS03740
uniprot id: A0A0X8FEB9
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS02795
gene id: 1376:AWM73_RS02795
uniprot id: A0A109RF88
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1376:AWM73 RS00935
gene id: 1376:AWM73_RS00935
uniprot id: A0A0X8FD80
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1376:AWM73 RS00960
gene id: 1376:AWM73_RS00960
uniprot id: A0A0X8FEQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS08740
gene id: 1376:AWM73_RS08740
uniprot id: A0A0X8FFW2
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS06390
gene id: 1376:AWM73_RS06390
uniprot id: A0A109REY1
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS02545
gene id: 1376:AWM73_RS02545
uniprot id: A0A329NE01
names: Similarity
messages: Belongs to the peptidase M20A family.

1376:AWM73 RS07920
gene id: 1376:AWM73_RS07920
uniprot id: A0A109REN5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1376:AWM73 RS03140
gene id: 1376:AWM73_RS03140
uniprot id: A0A0X8FDY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1376:AWM73 RS01595
gene id: 1376:AWM73_RS01595
uniprot id: A0A120I9L2
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1376:AWM73 RS08665
gene id: 1376:AWM73_RS08665
uniprot id: A0A0X8FFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS06080
gene id: 1376:AWM73_RS06080
uniprot id: A0A120I9V6
names: Similarity
messages: Belongs to the peptidase C1 family.

1376:AWM73 RS03180
gene id: 1376:AWM73_RS03180
uniprot id: A0A109RED0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS02205
gene id: 1376:AWM73_RS02205
uniprot id: A0A0X8FDM0
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1376:AWM73 RS01200
gene id: 1376:AWM73_RS01200
uniprot id: A0A109RE21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1376:AWM73 RS06030
gene id: 1376:AWM73_RS06030
uniprot id: A0A0X8FEX8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1376:AWM73 RS01855
gene id: 1376:AWM73_RS01855
uniprot id: A0A0X8FDP8
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1376:AWM73 RS08100
gene id: 1376:AWM73_RS08100
uniprot id: A0A0X8FFM4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1376:AWM73 RS07195
gene id: 1376:AWM73_RS07195
uniprot id: A0A0X8FFD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS05975
gene id: 1376:AWM73_RS05975
uniprot id: A0A120IA17
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

1376:AWM73 RS05085
gene id: 1376:AWM73_RS05085
uniprot id: A0A120I9T3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1376:AWM73 RS00915
gene id: 1376:AWM73_RS00915
uniprot id: A0A0X8FDA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1376:AWM73 RS03930
gene id: 1376:AWM73_RS03930
uniprot id: A0A109RED5
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS00660
gene id: 1376:AWM73_RS00660
uniprot id: A0A120I9J3
names: Similarity
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Homotetramer.

1376:AWM73 RS04735
gene id: 1376:AWM73_RS04735
uniprot id: A0A0X8FG38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1376:AWM73 RS07200
gene id: 1376:AWM73_RS07200
uniprot id: A0A0X8FFK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1376:AWM73 RS06660
gene id: 1376:AWM73_RS06660
uniprot id: A0A0X8FF46
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1376:AWM73 RS05055
gene id: 1376:AWM73_RS05055
uniprot id: A0A0X8FEL4
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1376:AWM73 RS01005
gene id: 1376:AWM73_RS01005
uniprot id: A0A0X8FD60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1376:AWM73 RS05595
gene id: 1376:AWM73_RS05595
uniprot id: A0A7T2RS20
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1376:AWM73 RS04610
gene id: 1376:AWM73_RS04610
uniprot id: A0A0X8FEH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1376:AWM73 RS04850
gene id: 1376:AWM73_RS04850
uniprot id: A0A0X8FEK7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1376:AWM73 RS02915
gene id: 1376:AWM73_RS02915
uniprot id: A0A109REA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

1376:AWM73 RS01690
gene id: 1376:AWM73_RS01690
uniprot id: A0A0X8FDK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1376:AWM73 RS02875
gene id: 1376:AWM73_RS02875
uniprot id: A0A0X8FE07
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1376:AWM73 RS01230
gene id: 1376:AWM73_RS01230
uniprot id: A0A7T2VU28
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1376:AWM73 RS01020
gene id: 1376:AWM73_RS01020
uniprot id: A0A0X8FDK7
names: Similarity
messages: Belongs to the DCK/DGK family.

1376:AWM73 RS07950
gene id: 1376:AWM73_RS07950
uniprot id: A0A0X8FFK5
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1376:AWM73 RS05090
gene id: 1376:AWM73_RS05090
uniprot id: A0A329NHV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1376:AWM73 RS07785
gene id: 1376:AWM73_RS07785
uniprot id: A0A7T2VSW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1376:AWM73 RS02380
gene id: 1376:AWM73_RS02380
uniprot id: A0A109REB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1376:AWM73 RS00215
gene id: 1376:AWM73_RS00215
uniprot id: A0A0X8FCZ3
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS08810
gene id: 1376:AWM73_RS08810
uniprot id: A0A0X8FFY9
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS08505
gene id: 1376:AWM73_RS08505
uniprot id: A0A7T2RR11
names: Similarity
messages: Belongs to the peptidase S11 family.

1376:AWM73 RS08930
gene id: 1376:AWM73_RS08930
uniprot id: A0A109REW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1376:AWM73 RS00220
gene id: 1376:AWM73_RS00220
uniprot id: A0A0X8FCW8
names: Similarity
messages: Belongs to the leucine-binding protein family.

1376:AWM73 RS06225
gene id: 1376:AWM73_RS06225
uniprot id: A0A109REM7
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS06625
gene id: 1376:AWM73_RS06625
uniprot id: A0A120I9W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1376:AWM73 RS05970
gene id: 1376:AWM73_RS05970
uniprot id: A0A0X8FGI0
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1376:AWM73 RS05980
gene id: 1376:AWM73_RS05980
uniprot id: A0A7T2RSL6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1376:AWM73 RS00725
gene id: 1376:AWM73_RS00725
uniprot id: A0A109RDW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1376:AWM73 RS06455
gene id: 1376:AWM73_RS06455
uniprot id: A0A0X8FGN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS04845
gene id: 1376:AWM73_RS04845
uniprot id: A0A0X8FEM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1376:AWM73 RS02835
gene id: 1376:AWM73_RS02835
uniprot id: A0A109RE96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS04080
gene id: 1376:AWM73_RS04080
uniprot id: A0A0X8FEM5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1376:AWM73 RS09105
gene id: 1376:AWM73_RS09105
uniprot id: A0A0X8FD25
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1376:AWM73 RS04685
gene id: 1376:AWM73_RS04685
uniprot id: A0A0X8FEI9
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS08365
gene id: 1376:AWM73_RS08365
uniprot id: A0A120I9Z8
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.

1376:AWM73 RS00295
gene id: 1376:AWM73_RS00295
uniprot id: A0A0X8FCX7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1376:AWM73 RS01930
gene id: 1376:AWM73_RS01930
uniprot id: A0A0X8FDI4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1376:AWM73 RS05460
gene id: 1376:AWM73_RS05460
uniprot id: A0A0X8FER6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1376:AWM73 RS06590
gene id: 1376:AWM73_RS06590
uniprot id: A0A0X8FF41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1376:AWM73 RS07870
gene id: 1376:AWM73_RS07870
uniprot id: A0A0X8FFL3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS02105
gene id: 1376:AWM73_RS02105
uniprot id: A0A0X8FDT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1376:AWM73 RS02890
gene id: 1376:AWM73_RS02890
uniprot id: A0A0X8FDV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1376:AWM73 RS02910
gene id: 1376:AWM73_RS02910
uniprot id: A0A0X8FDV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1376:AWM73 RS07045
gene id: 1376:AWM73_RS07045
uniprot id: A0A0X8FFA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1376:AWM73 RS02530
gene id: 1376:AWM73_RS02530
uniprot id: A0A120I9N2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS02630
gene id: 1376:AWM73_RS02630
uniprot id: A0A0X8FDX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1376:AWM73 RS08055
gene id: 1376:AWM73_RS08055
uniprot id: A0A0X8FH53
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS05585
gene id: 1376:AWM73_RS05585
uniprot id: A0A120I9U4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1376:AWM73 RS00405
gene id: 1376:AWM73_RS00405
uniprot id: A0A0X8FEH7
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1376:AWM73 RS01425
gene id: 1376:AWM73_RS01425
uniprot id: A0A109RE37
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1376:AWM73 RS06260
gene id: 1376:AWM73_RS06260
uniprot id: A0A0X8FF90
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS03840
gene id: 1376:AWM73_RS03840
uniprot id: A0A0X8FEI6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1376:AWM73 RS04705
gene id: 1376:AWM73_RS04705
uniprot id: A0A0X8FEH4
names: Similarity
messages: Belongs to the KdgT transporter family.

1376:AWM73 RS05655
gene id: 1376:AWM73_RS05655
uniprot id: A0A109REV3
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS08620
gene id: 1376:AWM73_RS08620
uniprot id: A0A109RES0
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS01845
gene id: 1376:AWM73_RS01845
uniprot id: A0A0X8FDM5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1376:AWM73 RS06190
gene id: 1376:AWM73_RS06190
uniprot id: A0A0X8FG37
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1376:AWM73 RS02665
gene id: 1376:AWM73_RS02665
uniprot id: A0A7T2VS53
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

1376:AWM73 RS06920
gene id: 1376:AWM73_RS06920
uniprot id: A0A120I9X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1376:AWM73 RS02190
gene id: 1376:AWM73_RS02190
uniprot id: A0A0X8FDN2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

1376:AWM73 RS02710
gene id: 1376:AWM73_RS02710
uniprot id: A0A0X8FDY3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1376:AWM73 RS01745
gene id: 1376:AWM73_RS01745
uniprot id: A0A109RE77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1376:AWM73 RS04585
gene id: 1376:AWM73_RS04585
uniprot id: A0A120I9S3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1376:AWM73 RS08285
gene id: 1376:AWM73_RS08285
uniprot id: A0A0X8FH86
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1376:AWM73 RS06955
gene id: 1376:AWM73_RS06955
uniprot id: A0A0X8FFG8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1376:AWM73 RS01265
gene id: 1376:AWM73_RS01265
uniprot id: A0A0X8FDN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1376:AWM73 RS02590
gene id: 1376:AWM73_RS02590
uniprot id: A0A0X8FE52
names: Similarity
messages: Belongs to the MecA family.

1376:AWM73 RS02445
gene id: 1376:AWM73_RS02445
uniprot id: A0A0X8FFA5
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS03565
gene id: 1376:AWM73_RS03565
uniprot id: A0A109RFQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1376:AWM73 RS08325
gene id: 1376:AWM73_RS08325
uniprot id: A0A0X8FFY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1376:AWM73 RS02670
gene id: 1376:AWM73_RS02670
uniprot id: A0A0X8FDS8
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1376:AWM73 RS01395
gene id: 1376:AWM73_RS01395
uniprot id: A0A0X8FDI8
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1376:AWM73 RS02510
gene id: 1376:AWM73_RS02510
uniprot id: A0A0X8FE42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1376:AWM73 RS00340
gene id: 1376:AWM73_RS00340
uniprot id: A0A109RFF5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1376:AWM73 RS00305
gene id: 1376:AWM73_RS00305
uniprot id: A0A0X8FCX8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1376:AWM73 RS07830
gene id: 1376:AWM73_RS07830
uniprot id: A0A120I9Y9
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1376:AWM73 RS00540
gene id: 1376:AWM73_RS00540
uniprot id: A0A7T2RQT6
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS04780
gene id: 1376:AWM73_RS04780
uniprot id: A0A0X8FEJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

1376:AWM73 RS08705
gene id: 1376:AWM73_RS08705
uniprot id: A0A0X8FFV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1376:AWM73 RS05915
gene id: 1376:AWM73_RS05915
uniprot id: A0A109REH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS01925
gene id: 1376:AWM73_RS01925
uniprot id: A0A0X8FDN6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1376:AWM73 RS01390
gene id: 1376:AWM73_RS01390
uniprot id: A0A0X8FDB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1376:AWM73 RS02460
gene id: 1376:AWM73_RS02460
uniprot id: A0A109RFM6
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1376:AWM73 RS02945
gene id: 1376:AWM73_RS02945
uniprot id: A0A7T2RQ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1376:AWM73 RS01965
gene id: 1376:AWM73_RS01965
uniprot id: A0A0X8FDJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS02050
gene id: 1376:AWM73_RS02050
uniprot id: A0A0X8FDK0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1376:AWM73 RS03465
gene id: 1376:AWM73_RS03465
uniprot id: A0A0X8FFM0
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1376:AWM73 RS02245
gene id: 1376:AWM73_RS02245
uniprot id: A0A0X8FDS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1376:AWM73 RS03865
gene id: 1376:AWM73_RS03865
uniprot id: A0A120I9R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1376:AWM73 RS04275
gene id: 1376:AWM73_RS04275
uniprot id: A0A109RFT3
names: Similarity
messages: Belongs to the PemK/MazF family.

1376:AWM73 RS03880
gene id: 1376:AWM73_RS03880
uniprot id: A0A120I9Q9
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS08600
gene id: 1376:AWM73_RS08600
uniprot id: A0A0X8FHC7
names: Subcellular Location Annotation
messages: cell wall

1376:AWM73 RS04975
gene id: 1376:AWM73_RS04975
uniprot id: A0A0X8FEY1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1376:AWM73 RS05940
gene id: 1376:AWM73_RS05940
uniprot id: A0A0X8FEW6
names: Similarity
messages: Belongs to the TPP enzyme family.

1376:AWM73 RS00620
gene id: 1376:AWM73_RS00620
uniprot id: A0A0X8FD15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1376:AWM73 RS04200
gene id: 1376:AWM73_RS04200
uniprot id: A0A0X8FEE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1376:AWM73 RS01695
gene id: 1376:AWM73_RS01695
uniprot id: A0A0X8FDK5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1376:AWM73 RS08880
gene id: 1376:AWM73_RS08880
uniprot id: A0A0X8FFX7
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS00160
gene id: 1376:AWM73_RS00160
uniprot id: A0A0X8FEE4
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1376:AWM73 RS01190
gene id: 1376:AWM73_RS01190
uniprot id: A0A329NN94
names: Similarity
messages: Belongs to the EamA transporter family.

1376:AWM73 RS01205
gene id: 1376:AWM73_RS01205
uniprot id: A0A0X8FET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS07365
gene id: 1376:AWM73_RS07365
uniprot id: A0A0X8FFL7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1376:AWM73 RS03730
gene id: 1376:AWM73_RS03730
uniprot id: A0A0X8FE77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1376:AWM73 RS01080
gene id: 1376:AWM73_RS01080
uniprot id: A0A0X8FD72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS00180
gene id: 1376:AWM73_RS00180
uniprot id: A0A7T2RQV6
names: Similarity
messages: Belongs to the peptidase M16 family.

1376:AWM73 RS01790
gene id: 1376:AWM73_RS01790
uniprot id: A0A0X8FDI6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1376:AWM73 RS01515
gene id: 1376:AWM73_RS01515
uniprot id: A0A109RE68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1376:AWM73 RS04060
gene id: 1376:AWM73_RS04060
uniprot id: A0A0X8FEH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1376:AWM73 RS08460
gene id: 1376:AWM73_RS08460
uniprot id: A0A109RG77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1376:AWM73 RS02595
gene id: 1376:AWM73_RS02595
uniprot id: A0A0X8FDS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

1376:AWM73 RS06930
gene id: 1376:AWM73_RS06930
uniprot id: A0A109RES4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1376:AWM73 RS01995
gene id: 1376:AWM73_RS01995
uniprot id: A0A7T2VTY2
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS06150
gene id: 1376:AWM73_RS06150
uniprot id: A0A109REX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1376:AWM73 RS06045
gene id: 1376:AWM73_RS06045
uniprot id: A0A0X8FFC5
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS04345
gene id: 1376:AWM73_RS04345
uniprot id: A0A120I9S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1376:AWM73 RS02490
gene id: 1376:AWM73_RS02490
uniprot id: A0A0X8FDY4
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1376:AWM73 RS03860
gene id: 1376:AWM73_RS03860
uniprot id: A0A120I9Q7
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1376:AWM73 RS06995
gene id: 1376:AWM73_RS06995
uniprot id: A0A109REQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1376:AWM73 RS01590
gene id: 1376:AWM73_RS01590
uniprot id: A0A120I9L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS05815
gene id: 1376:AWM73_RS05815
uniprot id: A0A0X8FGG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.
messages: Cell membrane
messages: Component of the accessory SecA2/SecY2 protein translocase complex required to export cell wall proteins. May form heterotrimers with SecE and SecG subunits.
messages: Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins. The central subunit of a protein translocation channel.

1376:AWM73 RS03195
gene id: 1376:AWM73_RS03195
uniprot id: A0A109RFP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1376:AWM73 RS02775
gene id: 1376:AWM73_RS02775
uniprot id: A0A120I9N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1376:AWM73 RS04205
gene id: 1376:AWM73_RS04205
uniprot id: A0A0X8FED6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1376:AWM73 RS02255
gene id: 1376:AWM73_RS02255
uniprot id: A0A0X8FDV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1376:AWM73 RS02870
gene id: 1376:AWM73_RS02870
uniprot id: A0A0X8FE02
names: Subcellular Location Annotation
messages: Cytoplasm

1376:AWM73 RS06855
gene id: 1376:AWM73_RS06855
uniprot id: A0A120I9W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1376:AWM73 RS05880
gene id: 1376:AWM73_RS05880
uniprot id: A0A7T2VTN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1376:AWM73 RS04615
gene id: 1376:AWM73_RS04615
uniprot id: A0A0X8FEH1
names: Similarity
messages: Belongs to the RecJ family.

1376:AWM73 RS03650
gene id: 1376:AWM73_RS03650
uniprot id: A0A0X8FE90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1376:AWM73 RS02720
gene id: 1376:AWM73_RS02720
uniprot id: A0A0X8FDU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1376:AWM73 RS02600
gene id: 1376:AWM73_RS02600
uniprot id: A0A109RE86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1376:AWM73 RS06360
gene id: 1376:AWM73_RS06360
uniprot id: A0A0X8FF21
names: Similarity
messages: Belongs to the UPF0342 family.

1376:AWM73 RS02200
gene id: 1376:AWM73_RS02200
uniprot id: A0A0X8FE04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1376:AWM73 RS05515
gene id: 1376:AWM73_RS05515
uniprot id: A0A0X8FET4
names: Similarity
messages: Belongs to the peptidase M24B family.

1376:AWM73 RS07595
gene id: 1376:AWM73_RS07595
uniprot id: A0A120I9Y4
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS04605
gene id: 1376:AWM73_RS04605
uniprot id: A0A0X8FEJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1376:AWM73 RS03820
gene id: 1376:AWM73_RS03820
uniprot id: A0A0X8FE55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1376:AWM73 RS01975
gene id: 1376:AWM73_RS01975
uniprot id: A0A0X8FF40
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1376:AWM73 RS07895
gene id: 1376:AWM73_RS07895
uniprot id: A0A0X8FH29
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1376:AWM73 RS08335
gene id: 1376:AWM73_RS08335
uniprot id: A0A0X8FFS2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1376:AWM73 RS04965
gene id: 1376:AWM73_RS04965
uniprot id: A0A0X8FEM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1376:AWM73 RS00565
gene id: 1376:AWM73_RS00565
uniprot id: A0A0X8FD12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1376:AWM73 RS06155
gene id: 1376:AWM73_RS06155
uniprot id: A0A109REP4
names: Similarity
messages: Belongs to the UPF0340 family.

1376:AWM73 RS07580
gene id: 1376:AWM73_RS07580
uniprot id: A0A0X8FFG1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1376:AWM73 RS03765
gene id: 1376:AWM73_RS03765
uniprot id: A0A0X8FE49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS03240
gene id: 1376:AWM73_RS03240
uniprot id: A0A0X8FDZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1376:AWM73 RS04980
gene id: 1376:AWM73_RS04980
uniprot id: A0A0X8FEK6
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1376:AWM73 RS08975
gene id: 1376:AWM73_RS08975
uniprot id: A0A0X8FG65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1376:AWM73 RS00400
gene id: 1376:AWM73_RS00400
uniprot id: A0A109RE58
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1376:AWM73 RS07080
gene id: 1376:AWM73_RS07080
uniprot id: A0A120I9X3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1376:AWM73 RS02115
gene id: 1376:AWM73_RS02115
uniprot id: A0A0X8FDM4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1376:AWM73 RS00280
gene id: 1376:AWM73_RS00280
uniprot id: A0A0X8FCX1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1376:AWM73 RS08760
gene id: 1376:AWM73_RS08760
uniprot id: A0A120IA10
names: Similarity
messages: Belongs to the sigma-54 factor family.

1376:AWM73 RS07165
gene id: 1376:AWM73_RS07165
uniprot id: A0A120I9X4
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS04155
gene id: 1376:AWM73_RS04155
uniprot id: A0A0X8FEN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1376:AWM73 RS02305
gene id: 1376:AWM73_RS02305
uniprot id: A0A120I9M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1376:AWM73 RS07370
gene id: 1376:AWM73_RS07370
uniprot id: A0A0X8FFD4
names: Similarity
messages: Belongs to the CtsR family.

1376:AWM73 RS02470
gene id: 1376:AWM73_RS02470
uniprot id: A0A109RFL1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1376:AWM73 RS02395
gene id: 1376:AWM73_RS02395
uniprot id: A0A7T2RQA7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS00945
gene id: 1376:AWM73_RS00945
uniprot id: A0A0X8FDJ7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1376:AWM73 RS02805
gene id: 1376:AWM73_RS02805
uniprot id: A0A0X8FE28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1376:AWM73 RS07075
gene id: 1376:AWM73_RS07075
uniprot id: A0A120I9X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1376:AWM73 RS07240
gene id: 1376:AWM73_RS07240
uniprot id: A0A0X8FGV7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS06650
gene id: 1376:AWM73_RS06650
uniprot id: A0A0X8FF67
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1376:AWM73 RS01735
gene id: 1376:AWM73_RS01735
uniprot id: A0A7T2VS46
names: Function
names: Similarity
messages: Belongs to the CpsD/CapB family.
messages: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide.

1376:AWM73 RS04090
gene id: 1376:AWM73_RS04090
uniprot id: A0A109REK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1376:AWM73 RS00365
gene id: 1376:AWM73_RS00365
uniprot id: A0A0X8FD50
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1376:AWM73 RS05870
gene id: 1376:AWM73_RS05870
uniprot id: A0A7T2RS88
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1376:AWM73 RS07960
gene id: 1376:AWM73_RS07960
uniprot id: A0A0X8FFK7
names: Similarity
messages: Belongs to the UPF0047 family.

1376:AWM73 RS00655
gene id: 1376:AWM73_RS00655
uniprot id: A0A120I9J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS05290
gene id: 1376:AWM73_RS05290
uniprot id: A0A0X8FEQ9
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS03265
gene id: 1376:AWM73_RS03265
uniprot id: A0A120I9P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1376:AWM73 RS00970
gene id: 1376:AWM73_RS00970
uniprot id: A0A109REB5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS02090
gene id: 1376:AWM73_RS02090
uniprot id: A0A0X8FDQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS08720
gene id: 1376:AWM73_RS08720
uniprot id: A0A0X8FFV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1376:AWM73 RS08195
gene id: 1376:AWM73_RS08195
uniprot id: A0A0X8FFP6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1376:AWM73 RS01340
gene id: 1376:AWM73_RS01340
uniprot id: A0A0X8FDP7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1376:AWM73 RS05050
gene id: 1376:AWM73_RS05050
uniprot id: A0A0X8FEM9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1376:AWM73 RS06220
gene id: 1376:AWM73_RS06220
uniprot id: A0A0X8FGK6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1376:AWM73 RS02285
gene id: 1376:AWM73_RS02285
uniprot id: A0A109RED6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1376:AWM73 RS00805
gene id: 1376:AWM73_RS00805
uniprot id: A0A0X8FEN0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1376:AWM73 RS04240
gene id: 1376:AWM73_RS04240
uniprot id: A0A0X8FEC4
names: Similarity
messages: Belongs to the ribF family.

1376:AWM73 RS05490
gene id: 1376:AWM73_RS05490
uniprot id: A0A109REG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1376:AWM73 RS07640
gene id: 1376:AWM73_RS07640
uniprot id: A0A0X8FFI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1376:AWM73 RS06820
gene id: 1376:AWM73_RS06820
uniprot id: A0A0X8FF73
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS01575
gene id: 1376:AWM73_RS01575
uniprot id: A0A0X8FDD7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1376:AWM73 RS02740
gene id: 1376:AWM73_RS02740
uniprot id: A0A0X8FDT7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1376:AWM73 RS01600
gene id: 1376:AWM73_RS01600
uniprot id: A0A120I9L9
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS03705
gene id: 1376:AWM73_RS03705
uniprot id: A0A120I9Q5
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS04935
gene id: 1376:AWM73_RS04935
uniprot id: A0A0X8FEL0
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1376:AWM73 RS04425
gene id: 1376:AWM73_RS04425
uniprot id: A0A120I9R7
names: Similarity
messages: Belongs to the peptidase S66 family.

1376:AWM73 RS01550
gene id: 1376:AWM73_RS01550
uniprot id: A0A0X8FDK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1376:AWM73 RS04130
gene id: 1376:AWM73_RS04130
uniprot id: A0A0X8FEA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS06875
gene id: 1376:AWM73_RS06875
uniprot id: A0A0X8FF95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1376:AWM73 RS04875
gene id: 1376:AWM73_RS04875
uniprot id: A0A0X8FEJ6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1376:AWM73 RS04860
gene id: 1376:AWM73_RS04860
uniprot id: A0A0X8FES3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1376:AWM73 RS04120
gene id: 1376:AWM73_RS04120
uniprot id: A0A0X8FED2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1376:AWM73 RS05620
gene id: 1376:AWM73_RS05620
uniprot id: A0A0X8FET1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1376:AWM73 RS06380
gene id: 1376:AWM73_RS06380
uniprot id: A0A0X8FGM5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1376:AWM73 RS02350
gene id: 1376:AWM73_RS02350
uniprot id: A0A0X8FE23
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1376:AWM73 RS00100
gene id: 1376:AWM73_RS00100
uniprot id: A0A0X8FD05
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1376:AWM73 RS02625
gene id: 1376:AWM73_RS02625
uniprot id: A0A109RE47
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1376:AWM73 RS05425
gene id: 1376:AWM73_RS05425
uniprot id: A0A0X8FES6
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS08040
gene id: 1376:AWM73_RS08040
uniprot id: A0A0X8FG06
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS03665
gene id: 1376:AWM73_RS03665
uniprot id: A0A0X8FEB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1376:AWM73 RS04720
gene id: 1376:AWM73_RS04720
uniprot id: A0A0X8FEV2
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS08890
gene id: 1376:AWM73_RS08890
uniprot id: A0A0X8FG57
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1376:AWM73 RS04525
gene id: 1376:AWM73_RS04525
uniprot id: A0A109RFT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cell envelope
messages: Cytoplasm

1376:AWM73 RS07030
gene id: 1376:AWM73_RS07030
uniprot id: A0A0X8FFH7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1376:AWM73 RS03255
gene id: 1376:AWM73_RS03255
uniprot id: A0A120I9P9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1376:AWM73 RS07040
gene id: 1376:AWM73_RS07040
uniprot id: A0A0X8FFB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1376:AWM73 RS03655
gene id: 1376:AWM73_RS03655
uniprot id: A0A0X8FE70
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1376:AWM73 RS04640
gene id: 1376:AWM73_RS04640
uniprot id: A0A0X8FEU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1376:AWM73 RS05695
gene id: 1376:AWM73_RS05695
uniprot id: A0A0X8FEV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1376:AWM73 RS08480
gene id: 1376:AWM73_RS08480
uniprot id: A0A7T2VSJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS05825
gene id: 1376:AWM73_RS05825
uniprot id: A0A7T2RSN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GtfB family.
messages: Cell membrane
messages: Forms a heterotetramer with 2 subunits each of GtfA and GtfB. Part of the accessory SecA2/SecY2 protein translocation apparatus.
messages: Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.

1376:AWM73 RS04710
gene id: 1376:AWM73_RS04710
uniprot id: A0A0X8FEJ2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1376:AWM73 RS04995
gene id: 1376:AWM73_RS04995
uniprot id: A0A7T2RP20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1376:AWM73 RS05795
gene id: 1376:AWM73_RS05795
uniprot id: A0A0X8FEV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1376:AWM73 RS04065
gene id: 1376:AWM73_RS04065
uniprot id: A0A0X8FE87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1376:AWM73 RS00850
gene id: 1376:AWM73_RS00850
uniprot id: A0A0X8FDB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1376:AWM73 RS04260
gene id: 1376:AWM73_RS04260
uniprot id: A0A109REF8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1376:AWM73 RS01095
gene id: 1376:AWM73_RS01095
uniprot id: A0A0X8FD81
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS02035
gene id: 1376:AWM73_RS02035
uniprot id: A0A0X8FDL6
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS04125
gene id: 1376:AWM73_RS04125
uniprot id: A0A0X8FEC0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1376:AWM73 RS02170
gene id: 1376:AWM73_RS02170
uniprot id: A0A0X8FDR4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1376:AWM73 RS08270
gene id: 1376:AWM73_RS08270
uniprot id: A0A0X8FG34
names: Similarity
messages: Belongs to the YoeB family.

1376:AWM73 RS06675
gene id: 1376:AWM73_RS06675
uniprot id: A0A0X8FFJ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS08575
gene id: 1376:AWM73_RS08575
uniprot id: A0A0X8FFV5
names: Similarity
messages: Belongs to the FemABX family.

1376:AWM73 RS02360
gene id: 1376:AWM73_RS02360
uniprot id: A0A109RE75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1376:AWM73 RS04140
gene id: 1376:AWM73_RS04140
uniprot id: A0A0X8FEA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1376:AWM73 RS02975
gene id: 1376:AWM73_RS02975
uniprot id: A0A0X8FDY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1376:AWM73 RS04880
gene id: 1376:AWM73_RS04880
uniprot id: A0A0X8FEX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1376:AWM73 RS05465
gene id: 1376:AWM73_RS05465
uniprot id: A0A0X8FF49
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1376:AWM73 RS08825
gene id: 1376:AWM73_RS08825
uniprot id: A0A0X8FFW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1376:AWM73 RS08710
gene id: 1376:AWM73_RS08710
uniprot id: A0A0X8FFW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1376:AWM73 RS08875
gene id: 1376:AWM73_RS08875
uniprot id: A0A0X8FG33
names: Similarity
messages: Belongs to the asparaginase 1 family.

1376:AWM73 RS02465
gene id: 1376:AWM73_RS02465
uniprot id: A0A0X8FHI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1376:AWM73 RS03095
gene id: 1376:AWM73_RS03095
uniprot id: A0A109REE1
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1376:AWM73 RS05665
gene id: 1376:AWM73_RS05665
uniprot id: A0A109REF7
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS08805
gene id: 1376:AWM73_RS08805
uniprot id: A0A0X8FFV8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1376:AWM73 RS04300
gene id: 1376:AWM73_RS04300
uniprot id: A0A0X8FEK3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1376:AWM73 RS04225
gene id: 1376:AWM73_RS04225
uniprot id: A0A0X8FED0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1376:AWM73 RS08785
gene id: 1376:AWM73_RS08785
uniprot id: A0A0X8FFX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1376:AWM73 RS07100
gene id: 1376:AWM73_RS07100
uniprot id: A0A0X8FG29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0213 family.
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1376:AWM73 RS04235
gene id: 1376:AWM73_RS04235
uniprot id: A0A0X8FEP4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1376:AWM73 RS07585
gene id: 1376:AWM73_RS07585
uniprot id: A0A109RF04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1376:AWM73 RS05775
gene id: 1376:AWM73_RS05775
uniprot id: A0A120IA21
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS03205
gene id: 1376:AWM73_RS03205
uniprot id: A0A0X8FE48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1376:AWM73 RS01415
gene id: 1376:AWM73_RS01415
uniprot id: A0A0X8FDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1376:AWM73 RS01010
gene id: 1376:AWM73_RS01010
uniprot id: A0A0X8FD87
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1376:AWM73 RS06740
gene id: 1376:AWM73_RS06740
uniprot id: A0A0X8FF71
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1376:AWM73 RS07325
gene id: 1376:AWM73_RS07325
uniprot id: A0A120I9X7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1376:AWM73 RS03470
gene id: 1376:AWM73_RS03470
uniprot id: A0A120I9Q1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1376:AWM73 RS04540
gene id: 1376:AWM73_RS04540
uniprot id: A0A0X8FEG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS07235
gene id: 1376:AWM73_RS07235
uniprot id: A0A109RF03
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1376:AWM73 RS04325
gene id: 1376:AWM73_RS04325
uniprot id: A0A0X8FEQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1376:AWM73 RS01285
gene id: 1376:AWM73_RS01285
uniprot id: A0A109RE62
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1376:AWM73 RS06665
gene id: 1376:AWM73_RS06665
uniprot id: A0A0X8FF60
names: Similarity
messages: Belongs to the LOG family.

1376:AWM73 RS06135
gene id: 1376:AWM73_RS06135
uniprot id: A0A109REL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1376:AWM73 RS00955
gene id: 1376:AWM73_RS00955
uniprot id: A0A109RDX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1376:AWM73 RS01530
gene id: 1376:AWM73_RS01530
uniprot id: A0A109RFH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1376:AWM73 RS00815
gene id: 1376:AWM73_RS00815
uniprot id: A0A109RDZ8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1376:AWM73 RS06945
gene id: 1376:AWM73_RS06945
uniprot id: A0A0X8FF98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1376:AWM73 RS05475
gene id: 1376:AWM73_RS05475
uniprot id: A0A109RER0
names: Similarity
messages: Belongs to the TlyA family.

1376:AWM73 RS08355
gene id: 1376:AWM73_RS08355
uniprot id: A0A109REX5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1376:AWM73 RS07750
gene id: 1376:AWM73_RS07750
uniprot id: A0A109RES7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1376:AWM73 RS05025
gene id: 1376:AWM73_RS05025
uniprot id: A0A0X8FEM7
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS00705
gene id: 1376:AWM73_RS00705
uniprot id: A0A0X8FD52
names: Similarity
messages: Belongs to the KdgT transporter family.

1376:AWM73 RS05890
gene id: 1376:AWM73_RS05890
uniprot id: A0A109REL1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1376:AWM73 RS01360
gene id: 1376:AWM73_RS01360
uniprot id: A0A120I9K6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1376:AWM73 RS06035
gene id: 1376:AWM73_RS06035
uniprot id: A0A0X8FEZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1376:AWM73 RS02620
gene id: 1376:AWM73_RS02620
uniprot id: A0A109REC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS02555
gene id: 1376:AWM73_RS02555
uniprot id: A0A0X8FDW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1376:AWM73 RS08750
gene id: 1376:AWM73_RS08750
uniprot id: A0A0X8FHE5
names: Subcellular Location Annotation
messages: Cytoplasm

1376:AWM73 RS01610
gene id: 1376:AWM73_RS01610
uniprot id: A0A7T2VU05
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS01915
gene id: 1376:AWM73_RS01915
uniprot id: A0A109RE17
names: Similarity
messages: Belongs to the threonine synthase family.

1376:AWM73 RS08650
gene id: 1376:AWM73_RS08650
uniprot id: A0A0X8FFW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1376:AWM73 RS00625
gene id: 1376:AWM73_RS00625
uniprot id: A0A0X8FD42
names: Similarity
messages: Belongs to the TrpF family.

1376:AWM73 RS04645
gene id: 1376:AWM73_RS04645
uniprot id: A0A0X8FEG8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1376:AWM73 RS05200
gene id: 1376:AWM73_RS05200
uniprot id: A0A0X8FEW3
names: Similarity
messages: Belongs to the LOR family.

1376:AWM73 RS05630
gene id: 1376:AWM73_RS05630
uniprot id: A0A0X8FET0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

1376:AWM73 RS01990
gene id: 1376:AWM73_RS01990
uniprot id: A0A109RFL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1376:AWM73 RS00170
gene id: 1376:AWM73_RS00170
uniprot id: A0A120I9I4
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1376:AWM73 RS05045
gene id: 1376:AWM73_RS05045
uniprot id: A0A7T2VS96
names: Similarity
messages: Belongs to the GARS family.

1376:AWM73 RS00040
gene id: 1376:AWM73_RS00040
uniprot id: A0A0X8FED5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1376:AWM73 RS08290
gene id: 1376:AWM73_RS08290
uniprot id: A0A120I9Z7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1376:AWM73 RS00395
gene id: 1376:AWM73_RS00395
uniprot id: A0A0X8FCZ0
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS01905
gene id: 1376:AWM73_RS01905
uniprot id: A0A109REE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS08375
gene id: 1376:AWM73_RS08375
uniprot id: A0A109REW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1376:AWM73 RS05920
gene id: 1376:AWM73_RS05920
uniprot id: A0A0X8FF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS05415
gene id: 1376:AWM73_RS05415
uniprot id: A0A109REE9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1376:AWM73 RS03635
gene id: 1376:AWM73_RS03635
uniprot id: A0A120I9Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1376:AWM73 RS05380
gene id: 1376:AWM73_RS05380
uniprot id: A0A0X8FF38
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1376:AWM73 RS08045
gene id: 1376:AWM73_RS08045
uniprot id: A0A7T2RR74
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS01860
gene id: 1376:AWM73_RS01860
uniprot id: A0A0X8FDG9
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1376:AWM73 RS01115
gene id: 1376:AWM73_RS01115
uniprot id: A0A0X8FG47
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1376:AWM73 RS06835
gene id: 1376:AWM73_RS06835
uniprot id: A0A109REX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS08020
gene id: 1376:AWM73_RS08020
uniprot id: A0A0X8FFV0
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS04440
gene id: 1376:AWM73_RS04440
uniprot id: A0A109REB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS03965
gene id: 1376:AWM73_RS03965
uniprot id: A0A0X8FEC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1376:AWM73 RS04765
gene id: 1376:AWM73_RS04765
uniprot id: A0A0X8FEL2
names: Subcellular Location Annotation
messages: Cytoplasm

1376:AWM73 RS00350
gene id: 1376:AWM73_RS00350
uniprot id: A0A0X8FD35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1376:AWM73 RS02660
gene id: 1376:AWM73_RS02660
uniprot id: A0A0X8FDS9
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1376:AWM73 RS06810
gene id: 1376:AWM73_RS06810
uniprot id: A0A0X8FF64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1376:AWM73 RS05420
gene id: 1376:AWM73_RS05420
uniprot id: A0A7T2VTE0
names: Function
names: Similarity
messages: Belongs to the CpsD/CapB family.
messages: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide.

1376:AWM73 RS02960
gene id: 1376:AWM73_RS02960
uniprot id: A0A0X8FDY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1376:AWM73 RS08070
gene id: 1376:AWM73_RS08070
uniprot id: A0A120I9Z2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1376:AWM73 RS03550
gene id: 1376:AWM73_RS03550
uniprot id: A0A109RED7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1376:AWM73 RS05965
gene id: 1376:AWM73_RS05965
uniprot id: A0A109RES8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1376:AWM73 RS01660
gene id: 1376:AWM73_RS01660
uniprot id: A0A109RE48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1376:AWM73 RS03845
gene id: 1376:AWM73_RS03845
uniprot id: A0A0X8FE74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1376:AWM73 RS03850
gene id: 1376:AWM73_RS03850
uniprot id: A0A109REJ1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1376:AWM73 RS06305
gene id: 1376:AWM73_RS06305
uniprot id: A0A120I9V7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS04920
gene id: 1376:AWM73_RS04920
uniprot id: A0A109RED3
names: Similarity
messages: Belongs to the UPF0297 family.

1376:AWM73 RS07295
gene id: 1376:AWM73_RS07295
uniprot id: A0A0X8FG26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1376:AWM73 RS07720
gene id: 1376:AWM73_RS07720
uniprot id: A0A0X8FFH8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1376:AWM73 RS04245
gene id: 1376:AWM73_RS04245
uniprot id: A0A109REI5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1376:AWM73 RS06960
gene id: 1376:AWM73_RS06960
uniprot id: A0A0X8FF84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1376:AWM73 RS06800
gene id: 1376:AWM73_RS06800
uniprot id: A0A0X8FF85
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1376:AWM73 RS01235
gene id: 1376:AWM73_RS01235
uniprot id: A0A0X8FDE5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1376:AWM73 RS06110
gene id: 1376:AWM73_RS06110
uniprot id: A0A7T2RSC6
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS04160
gene id: 1376:AWM73_RS04160
uniprot id: A0A0X8FEB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1376:AWM73 RS03630
gene id: 1376:AWM73_RS03630
uniprot id: A0A120I9Q2
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1376:AWM73 RS04480
gene id: 1376:AWM73_RS04480
uniprot id: A0A0X8FEG1
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

1376:AWM73 RS01030
gene id: 1376:AWM73_RS01030
uniprot id: A0A109RE25
names: Similarity
messages: Belongs to the IMPACT family.

1376:AWM73 RS06270
gene id: 1376:AWM73_RS06270
uniprot id: A0A0X8FF22
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1376:AWM73 RS04105
gene id: 1376:AWM73_RS04105
uniprot id: A0A120I9R3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1376:AWM73 RS04580
gene id: 1376:AWM73_RS04580
uniprot id: A0A0X8FG17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1376:AWM73 RS04360
gene id: 1376:AWM73_RS04360
uniprot id: A0A120I9R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1376:AWM73 RS07530
gene id: 1376:AWM73_RS07530
uniprot id: A0A109RG50
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1376:AWM73 RS04000
gene id: 1376:AWM73_RS04000
uniprot id: A0A0X8FEL5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Homohexamer.

1376:AWM73 RS07430
gene id: 1376:AWM73_RS07430
uniprot id: A0A109REQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1376:AWM73 RS02580
gene id: 1376:AWM73_RS02580
uniprot id: A0A0X8FDT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1376:AWM73 RS02765
gene id: 1376:AWM73_RS02765
uniprot id: A0A120I9P1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1376:AWM73 RS04020
gene id: 1376:AWM73_RS04020
uniprot id: A0A0X8FFU7
names: Similarity
messages: Belongs to the RNase H family.

1376:AWM73 RS06370
gene id: 1376:AWM73_RS06370
uniprot id: A0A0X8FF26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS03900
gene id: 1376:AWM73_RS03900
uniprot id: A0A0X8FEF7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS07020
gene id: 1376:AWM73_RS07020
uniprot id: A0A7T2VST6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1376:AWM73 RS00925
gene id: 1376:AWM73_RS00925
uniprot id: A0A0X8FDC8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1376:AWM73 RS02150
gene id: 1376:AWM73_RS02150
uniprot id: A0A109REF4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1376:AWM73 RS02575
gene id: 1376:AWM73_RS02575
uniprot id: A0A0X8FDR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS08970
gene id: 1376:AWM73_RS08970
uniprot id: A0A0X8FFZ5
names: Similarity
messages: Belongs to the peptidase M20A family.

1376:AWM73 RS02565
gene id: 1376:AWM73_RS02565
uniprot id: A0A0X8FDR6
names: Similarity
messages: Belongs to the Dps family.

1376:AWM73 RS02715
gene id: 1376:AWM73_RS02715
uniprot id: A0A0X8FDY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

1376:AWM73 RS03510
gene id: 1376:AWM73_RS03510
uniprot id: A0A0X8FE85
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1376:AWM73 RS00475
gene id: 1376:AWM73_RS00475
uniprot id: A0A0X8FCZ8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1376:AWM73 RS06935
gene id: 1376:AWM73_RS06935
uniprot id: A0A109REL2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1376:AWM73 RS05495
gene id: 1376:AWM73_RS05495
uniprot id: A0A109RFX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1376:AWM73 RS08605
gene id: 1376:AWM73_RS08605
uniprot id: A0A120IA02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1376:AWM73 RS07135
gene id: 1376:AWM73_RS07135
uniprot id: A0A0X8FFB5
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1376:AWM73 RS08235
gene id: 1376:AWM73_RS08235
uniprot id: A0A7T2RRG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1376:AWM73 RS03520
gene id: 1376:AWM73_RS03520
uniprot id: A0A0X8FE36
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1376:AWM73 RS00175
gene id: 1376:AWM73_RS00175
uniprot id: A0A120I9H9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1376:AWM73 RS05700
gene id: 1376:AWM73_RS05700
uniprot id: A0A0X8FEU4
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1376:AWM73 RS02110
gene id: 1376:AWM73_RS02110
uniprot id: A0A0X8FDK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1376:AWM73 RS05545
gene id: 1376:AWM73_RS05545
uniprot id: A0A7T2RP72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1376:AWM73 RS03800
gene id: 1376:AWM73_RS03800
uniprot id: A0A0X8FEA5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1376:AWM73 RS00610
gene id: 1376:AWM73_RS00610
uniprot id: A0A0X8FD14
names: Similarity
messages: Belongs to the peptidase S49 family.

1376:AWM73 RS08030
gene id: 1376:AWM73_RS08030
uniprot id: A0A0X8FFN5
names: Subcellular Location Annotation
messages: Cytoplasm

1376:AWM73 RS02735
gene id: 1376:AWM73_RS02735
uniprot id: A0A0X8FDV4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS08265
gene id: 1376:AWM73_RS08265
uniprot id: A0A0X8FFP8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1376:AWM73 RS02650
gene id: 1376:AWM73_RS02650
uniprot id: A0A0X8FDS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1376:AWM73 RS07175
gene id: 1376:AWM73_RS07175
uniprot id: A0A109RET4
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS01705
gene id: 1376:AWM73_RS01705
uniprot id: A0A0X8FDM8
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1376:AWM73 RS02815
gene id: 1376:AWM73_RS02815
uniprot id: A0A0X8FDW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1376:AWM73 RS08530
gene id: 1376:AWM73_RS08530
uniprot id: A0A120IA03
names: Similarity
messages: Belongs to the FemABX family.

1376:AWM73 RS03670
gene id: 1376:AWM73_RS03670
uniprot id: A0A0X8FE32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS06285
gene id: 1376:AWM73_RS06285
uniprot id: A0A0X8FF17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1376:AWM73 RS05635
gene id: 1376:AWM73_RS05635
uniprot id: A0A109REK1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1376:AWM73 RS09010
gene id: 1376:AWM73_RS09010
uniprot id: A0A329NZK9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1376:AWM73 RS03120
gene id: 1376:AWM73_RS03120
uniprot id: A0A0X8FDZ9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1376:AWM73 RS08080
gene id: 1376:AWM73_RS08080
uniprot id: A0A0X8FFS3
names: Subcellular Location Annotation
messages: Cytoplasm

1376:AWM73 RS05575
gene id: 1376:AWM73_RS05575
uniprot id: A0A120I9U5
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1376:AWM73 RS00115
gene id: 1376:AWM73_RS00115
uniprot id: A0A0X8FD17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1376:AWM73 RS08595
gene id: 1376:AWM73_RS08595
uniprot id: A0A109REY3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1376:AWM73 RS06235
gene id: 1376:AWM73_RS06235
uniprot id: A0A109RG05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS06375
gene id: 1376:AWM73_RS06375
uniprot id: A0A109REM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1376:AWM73 RS04035
gene id: 1376:AWM73_RS04035
uniprot id: A0A109RFS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS08445
gene id: 1376:AWM73_RS08445
uniprot id: A0A109REU9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1376:AWM73 RS05500
gene id: 1376:AWM73_RS05500
uniprot id: A0A109RFW5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1376:AWM73 RS06845
gene id: 1376:AWM73_RS06845
uniprot id: A0A120I9W8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1376:AWM73 RS05550
gene id: 1376:AWM73_RS05550
uniprot id: A0A0X8FES0
names: Similarity
messages: Belongs to the GSP E family.

1376:AWM73 RS03295
gene id: 1376:AWM73_RS03295
uniprot id: A0A0X8FE78
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1376:AWM73 RS04330
gene id: 1376:AWM73_RS04330
uniprot id: A0A0X8FEC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1376:AWM73 RS06975
gene id: 1376:AWM73_RS06975
uniprot id: A0A0X8FFN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1376:AWM73 RS01945
gene id: 1376:AWM73_RS01945
uniprot id: A0A0X8FDK6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1376:AWM73 RS05930
gene id: 1376:AWM73_RS05930
uniprot id: A0A0X8FEY0
names: Function
names: Similarity
names: Subunit
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.

1376:AWM73 RS03645
gene id: 1376:AWM73_RS03645
uniprot id: A0A120I9Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1376:AWM73 RS06890
gene id: 1376:AWM73_RS06890
uniprot id: A0A0X8FF89
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1376:AWM73 RS00235
gene id: 1376:AWM73_RS00235
uniprot id: A0A2N6PAW1
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS07215
gene id: 1376:AWM73_RS07215
uniprot id: A0A0X8FFD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1376:AWM73 RS02820
gene id: 1376:AWM73_RS02820
uniprot id: A0A0X8FDU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS07065
gene id: 1376:AWM73_RS07065
uniprot id: A0A7T2RS22
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS01780
gene id: 1376:AWM73_RS01780
uniprot id: A0A0X8FDN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1376:AWM73 RS06160
gene id: 1376:AWM73_RS06160
uniprot id: A0A109REI2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1376:AWM73 RS04955
gene id: 1376:AWM73_RS04955
uniprot id: A0A7T2VUZ9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1376:AWM73 RS05210
gene id: 1376:AWM73_RS05210
uniprot id: A0A0X8FEP9
names: Similarity
messages: Belongs to the ArsC family.

1376:AWM73 RS07705
gene id: 1376:AWM73_RS07705
uniprot id: A0A0X8FFR3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1376:AWM73 RS07540
gene id: 1376:AWM73_RS07540
uniprot id: A0A0X8FFJ6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1376:AWM73 RS02965
gene id: 1376:AWM73_RS02965
uniprot id: A0A0X8FE43
names: Similarity
messages: Belongs to the CinA family.

1376:AWM73 RS00240
gene id: 1376:AWM73_RS00240
uniprot id: A0A109RDV1
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS00050
gene id: 1376:AWM73_RS00050
uniprot id: A0A7T2VSF8
names: Similarity
messages: Belongs to the UPF0177 family.

1376:AWM73 RS05625
gene id: 1376:AWM73_RS05625
uniprot id: A0A0X8FF70
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1376:AWM73 RS07520
gene id: 1376:AWM73_RS07520
uniprot id: A0A109RER9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1376:AWM73 RS02135
gene id: 1376:AWM73_RS02135
uniprot id: A0A109RE65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1376:AWM73 RS02335
gene id: 1376:AWM73_RS02335
uniprot id: A0A7T2VSQ6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1376:AWM73 RS04285
gene id: 1376:AWM73_RS04285
uniprot id: A0A0X8FEF1
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1376:AWM73 RS08965
gene id: 1376:AWM73_RS08965
uniprot id: A0A0X8FFZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1376:AWM73 RS03905
gene id: 1376:AWM73_RS03905
uniprot id: A0A0X8FE63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1376:AWM73 RS08725
gene id: 1376:AWM73_RS08725
uniprot id: A0A0X8FFX5
names: Similarity
messages: Belongs to the UPF0145 family.

1376:AWM73 RS02300
gene id: 1376:AWM73_RS02300
uniprot id: A0A120I9M7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1376:AWM73 RS01260
gene id: 1376:AWM73_RS01260
uniprot id: A0A0X8FDA1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1376:AWM73 RS03620
gene id: 1376:AWM73_RS03620
uniprot id: A0A109REI3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1376:AWM73 RS03305
gene id: 1376:AWM73_RS03305
uniprot id: A0A0X8FE24
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1376:AWM73 RS08305
gene id: 1376:AWM73_RS08305
uniprot id: A0A120IA01
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1376:AWM73 RS03925
gene id: 1376:AWM73_RS03925
uniprot id: A0A0X8FE84
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS06865
gene id: 1376:AWM73_RS06865
uniprot id: A0A0X8FFB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1376:AWM73 RS00715
gene id: 1376:AWM73_RS00715
uniprot id: A0A329NJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1376:AWM73 RS04215
gene id: 1376:AWM73_RS04215
uniprot id: A0A0X8FEJ4
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS02435
gene id: 1376:AWM73_RS02435
uniprot id: A0A0X8FDQ0
names: Similarity
messages: Belongs to the LuxC family.

1376:AWM73 RS02635
gene id: 1376:AWM73_RS02635
uniprot id: A0A0X8FDX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1376:AWM73 RS08300
gene id: 1376:AWM73_RS08300
uniprot id: A0A120I9Z9
names: Similarity
messages: Belongs to the thioredoxin family.

1376:AWM73 RS08795
gene id: 1376:AWM73_RS08795
uniprot id: A0A0X8FGB7
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1376:AWM73 RS00335
gene id: 1376:AWM73_RS00335
uniprot id: A0A7T2RQT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS02700
gene id: 1376:AWM73_RS02700
uniprot id: A0A109RFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1376:AWM73 RS04790
gene id: 1376:AWM73_RS04790
uniprot id: A0A0X8FEI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1376:AWM73 RS02210
gene id: 1376:AWM73_RS02210
uniprot id: A0A109RE71
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1376:AWM73 RS08570
gene id: 1376:AWM73_RS08570
uniprot id: A0A0X8FFT1
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS07160
gene id: 1376:AWM73_RS07160
uniprot id: A0A0X8FGV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1376:AWM73 RS02165
gene id: 1376:AWM73_RS02165
uniprot id: A0A7T2RQ87
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1376:AWM73 RS01725
gene id: 1376:AWM73_RS01725
uniprot id: A0A0X8FDU5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1376:AWM73 RS04915
gene id: 1376:AWM73_RS04915
uniprot id: A0A109REL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1376:AWM73 RS08745
gene id: 1376:AWM73_RS08745
uniprot id: A0A109RF54
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS04185
gene id: 1376:AWM73_RS04185
uniprot id: A0A109REQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1376:AWM73 RS04725
gene id: 1376:AWM73_RS04725
uniprot id: A0A0X8FEH8
names: Similarity
messages: Belongs to the peptidase S49 family.

1376:AWM73 RS05590
gene id: 1376:AWM73_RS05590
uniprot id: A0A0X8FEW2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1376:AWM73 RS01250
gene id: 1376:AWM73_RS01250
uniprot id: A0A0X8FD91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1376:AWM73 RS06990
gene id: 1376:AWM73_RS06990
uniprot id: A0A0X8FGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1376:AWM73 RS07300
gene id: 1376:AWM73_RS07300
uniprot id: A0A0X8FFC9
names: Similarity
messages: Belongs to the UPF0213 family.

1376:AWM73 RS08775
gene id: 1376:AWM73_RS08775
uniprot id: A0A0X8FG20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

1376:AWM73 RS04335
gene id: 1376:AWM73_RS04335
uniprot id: A0A109REL4
names: Similarity
messages: Belongs to the DprA/Smf family.

1376:AWM73 RS08050
gene id: 1376:AWM73_RS08050
uniprot id: A0A109RF23
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1376:AWM73 RS02495
gene id: 1376:AWM73_RS02495
uniprot id: A0A0X8FDQ6
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1376:AWM73 RS00265
gene id: 1376:AWM73_RS00265
uniprot id: A0A109RDR6
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1376:AWM73 RS03895
gene id: 1376:AWM73_RS03895
uniprot id: A0A0X8FE65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1376:AWM73 RS02535
gene id: 1376:AWM73_RS02535
uniprot id: A0A120I9N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1376:AWM73 RS00300
gene id: 1376:AWM73_RS00300
uniprot id: A0A0X8FD03
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1376:AWM73 RS07725
gene id: 1376:AWM73_RS07725
uniprot id: A0A7T2RRB8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1376:AWM73 RS08715
gene id: 1376:AWM73_RS08715
uniprot id: A0A0X8FG35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1376:AWM73 RS06595
gene id: 1376:AWM73_RS06595
uniprot id: A0A0X8FFI6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1376:AWM73 RS08490
gene id: 1376:AWM73_RS08490
uniprot id: A0A0X8FFS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1376:AWM73 RS06195
gene id: 1376:AWM73_RS06195
uniprot id: A0A0X8FF14
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1376:AWM73 RS00630
gene id: 1376:AWM73_RS00630
uniprot id: A0A0X8FD18
names: Similarity
messages: Belongs to the TrpC family.

1376:AWM73 RS04150
gene id: 1376:AWM73_RS04150
uniprot id: A0A0X8FEA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1376:AWM73 RS05040
gene id: 1376:AWM73_RS05040
uniprot id: A0A0X8FEU6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1376:AWM73 RS02860
gene id: 1376:AWM73_RS02860
uniprot id: A0A109REZ8
names: Similarity
messages: Belongs to the YggT family.

1376:AWM73 RS05260
gene id: 1376:AWM73_RS05260
uniprot id: A0A109RFV5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1376:AWM73 RS04050
gene id: 1376:AWM73_RS04050
uniprot id: A0A0X8FEA6
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS08940
gene id: 1376:AWM73_RS08940
uniprot id: A0A109RGA4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1376:AWM73 RS08895
gene id: 1376:AWM73_RS08895
uniprot id: A0A0X8FFW9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1376:AWM73 RS05985
gene id: 1376:AWM73_RS05985
uniprot id: A0A109REM1
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS08700
gene id: 1376:AWM73_RS08700
uniprot id: A0A0X8FG08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1376:AWM73 RS03475
gene id: 1376:AWM73_RS03475
uniprot id: A0A109REJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1376:AWM73 RS07985
gene id: 1376:AWM73_RS07985
uniprot id: A0A109RET8
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS05840
gene id: 1376:AWM73_RS05840
uniprot id: A0A120I9V0
names: Similarity
messages: Belongs to the peptidase M20A family.

1376:AWM73 RS01920
gene id: 1376:AWM73_RS01920
uniprot id: A0A0X8FDN9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS02185
gene id: 1376:AWM73_RS02185
uniprot id: A0A0X8FDL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1376:AWM73 RS04380
gene id: 1376:AWM73_RS04380
uniprot id: A0A0X8FEL3
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS06735
gene id: 1376:AWM73_RS06735
uniprot id: A0A0X8FF56
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1376:AWM73 RS05095
gene id: 1376:AWM73_RS05095
uniprot id: A0A0X8FG42
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1376:AWM73 RS02320
gene id: 1376:AWM73_RS02320
uniprot id: A0A0X8FDT9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1376:AWM73 RS00635
gene id: 1376:AWM73_RS00635
uniprot id: A0A0X8FDF3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS01405
gene id: 1376:AWM73_RS01405
uniprot id: A0A0X8FDD8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS04900
gene id: 1376:AWM73_RS04900
uniprot id: A0A120I9S7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1376:AWM73 RS07435
gene id: 1376:AWM73_RS07435
uniprot id: A0A0X8FGX2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1376:AWM73 RS03675
gene id: 1376:AWM73_RS03675
uniprot id: A0A0X8FE61
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1376:AWM73 RS04865
gene id: 1376:AWM73_RS04865
uniprot id: A0A0X8FEJ0
names: Similarity
messages: Belongs to the fabD family.

1376:AWM73 RS04555
gene id: 1376:AWM73_RS04555
uniprot id: A0A0X8FEH0
names: Similarity
messages: Belongs to the universal stress protein A family.

1376:AWM73 RS01470
gene id: 1376:AWM73_RS01470
uniprot id: A0A0X8FDC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1376:AWM73 RS01750
gene id: 1376:AWM73_RS01750
uniprot id: A0A109RE33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1376:AWM73 RS02810
gene id: 1376:AWM73_RS02810
uniprot id: A0A0X8FDU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1376:AWM73 RS07565
gene id: 1376:AWM73_RS07565
uniprot id: A0A0X8FFH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1376:AWM73 RS03975
gene id: 1376:AWM73_RS03975
uniprot id: A0A0X8FE79
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1376:AWM73 RS06925
gene id: 1376:AWM73_RS06925
uniprot id: A0A109RF05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1376:AWM73 RS07250
gene id: 1376:AWM73_RS07250
uniprot id: A0A109REQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1376:AWM73 RS02065
gene id: 1376:AWM73_RS02065
uniprot id: A0A120I9M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1376:AWM73 RS02695
gene id: 1376:AWM73_RS02695
uniprot id: A0A109RE72
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1376:AWM73 RS03145
gene id: 1376:AWM73_RS03145
uniprot id: A0A0X8FEB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1376:AWM73 RS08900
gene id: 1376:AWM73_RS08900
uniprot id: A0A0X8FFZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1376:AWM73 RS07000
gene id: 1376:AWM73_RS07000
uniprot id: A0A109REP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1376:AWM73 RS06940
gene id: 1376:AWM73_RS06940
uniprot id: A0A0X8FFC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1376:AWM73 RS02970
gene id: 1376:AWM73_RS02970
uniprot id: A0A0X8FDW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1376:AWM73 RS05510
gene id: 1376:AWM73_RS05510
uniprot id: A0A0X8FET6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1376:AWM73 RS03495
gene id: 1376:AWM73_RS03495
uniprot id: A0A0X8FE83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1376:AWM73 RS01050
gene id: 1376:AWM73_RS01050
uniprot id: A0A109RFI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1376:AWM73 RS02955
gene id: 1376:AWM73_RS02955
uniprot id: A0A0X8FE16
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1376:AWM73 RS04475
gene id: 1376:AWM73_RS04475
uniprot id: A0A7T2VSM8
names: Similarity
messages: Belongs to the peptidase M20A family.

1376:AWM73 RS03505
gene id: 1376:AWM73_RS03505
uniprot id: A0A7T2RPU5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1376:AWM73 RS08915
gene id: 1376:AWM73_RS08915
uniprot id: A0A0X8FFX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1376:AWM73 RS02745
gene id: 1376:AWM73_RS02745
uniprot id: A0A0X8FE71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1376:AWM73 RS03795
gene id: 1376:AWM73_RS03795
uniprot id: A0A109RFQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1376:AWM73 RS03190
gene id: 1376:AWM73_RS03190
uniprot id: A0A109RFP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1376:AWM73 RS03600
gene id: 1376:AWM73_RS03600
uniprot id: A0A0X8FE47
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1376:AWM73 RS03250
gene id: 1376:AWM73_RS03250
uniprot id: A0A0X8FFK6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1376:AWM73 RS06645
gene id: 1376:AWM73_RS06645
uniprot id: A0A0X8FF59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1376:AWM73 RS04255
gene id: 1376:AWM73_RS04255
uniprot id: A0A0X8FFX6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1376:AWM73 RS04730
gene id: 1376:AWM73_RS04730
uniprot id: A0A109REK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS07850
gene id: 1376:AWM73_RS07850
uniprot id: A0A0X8FFK1
names: Similarity
messages: Belongs to the FBPase class 3 family.

1376:AWM73 RS04115
gene id: 1376:AWM73_RS04115
uniprot id: A0A120I9R5
names: Similarity
messages: Belongs to the CapA family.

1376:AWM73 RS04930
gene id: 1376:AWM73_RS04930
uniprot id: A0A0X8FEL7
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1376:AWM73 RS08675
gene id: 1376:AWM73_RS08675
uniprot id: A0A0X8FHD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1376:AWM73 RS01045
gene id: 1376:AWM73_RS01045
uniprot id: A0A109RE09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1376:AWM73 RS05845
gene id: 1376:AWM73_RS05845
uniprot id: A0A0X8FEZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1376:AWM73 RS03745
gene id: 1376:AWM73_RS03745
uniprot id: A0A0X8FE46
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS02225
gene id: 1376:AWM73_RS02225
uniprot id: A0A109RE53
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS04340
gene id: 1376:AWM73_RS04340
uniprot id: A0A0X8FFY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1376:AWM73 RS02180
gene id: 1376:AWM73_RS02180
uniprot id: A0A0X8FDU4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1376:AWM73 RS05680
gene id: 1376:AWM73_RS05680
uniprot id: A0A0X8FEV3
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS05885
gene id: 1376:AWM73_RS05885
uniprot id: A0A0X8FEW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1376:AWM73 RS02250
gene id: 1376:AWM73_RS02250
uniprot id: A0A0X8FDM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1376:AWM73 RS04600
gene id: 1376:AWM73_RS04600
uniprot id: A0A120I9S4
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1376:AWM73 RS08685
gene id: 1376:AWM73_RS08685
uniprot id: A0A109REZ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS05345
gene id: 1376:AWM73_RS05345
uniprot id: A0A0X8FET5
names: Similarity
messages: Belongs to the PemK/MazF family.

1376:AWM73 RS07570
gene id: 1376:AWM73_RS07570
uniprot id: A0A0X8FFG0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1376:AWM73 RS04840
gene id: 1376:AWM73_RS04840
uniprot id: A0A120I9T0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1376:AWM73 RS00940
gene id: 1376:AWM73_RS00940
uniprot id: A0A0X8FD61
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS02855
gene id: 1376:AWM73_RS02855
uniprot id: A0A109RED4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1376:AWM73 RS03885
gene id: 1376:AWM73_RS03885
uniprot id: A0A0X8FEB5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS06275
gene id: 1376:AWM73_RS06275
uniprot id: A0A7T2RS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1376:AWM73 RS03915
gene id: 1376:AWM73_RS03915
uniprot id: A0A0X8FE64
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1376:AWM73 RS00390
gene id: 1376:AWM73_RS00390
uniprot id: A0A0X8FDC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1376:AWM73 RS02080
gene id: 1376:AWM73_RS02080
uniprot id: A0A120I9M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS07780
gene id: 1376:AWM73_RS07780
uniprot id: A0A0X8FFK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1376:AWM73 RS02505
gene id: 1376:AWM73_RS02505
uniprot id: A0A0X8FDR1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1376:AWM73 RS00380
gene id: 1376:AWM73_RS00380
uniprot id: A0A0X8FD13
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1376:AWM73 RS05705
gene id: 1376:AWM73_RS05705
uniprot id: A0A0X8FF81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cell envelope

1376:AWM73 RS04030
gene id: 1376:AWM73_RS04030
uniprot id: A0A109REB8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1376:AWM73 RS02215
gene id: 1376:AWM73_RS02215
uniprot id: A0A0X8FF72
names: Similarity
messages: Belongs to the FemABX family.

1376:AWM73 RS06915
gene id: 1376:AWM73_RS06915
uniprot id: A0A0X8FGS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1376:AWM73 RS08845
gene id: 1376:AWM73_RS08845
uniprot id: A0A329NKD5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1376:AWM73 RS00820
gene id: 1376:AWM73_RS00820
uniprot id: A0A109RFH2
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1376:AWM73 RS07120
gene id: 1376:AWM73_RS07120
uniprot id: A0A0X8FFC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

1376:AWM73 RS03680
gene id: 1376:AWM73_RS03680
uniprot id: A0A0X8FE40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS03125
gene id: 1376:AWM73_RS03125
uniprot id: A0A0X8FE60
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS08345
gene id: 1376:AWM73_RS08345
uniprot id: A0A0X8FG44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1376:AWM73 RS04715
gene id: 1376:AWM73_RS04715
uniprot id: A0A0X8FEH5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1376:AWM73 RS06765
gene id: 1376:AWM73_RS06765
uniprot id: A0A0X8FGR1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS02155
gene id: 1376:AWM73_RS02155
uniprot id: A0A109REA6
names: Similarity
messages: Belongs to the asp23 family.

1376:AWM73 RS03200
gene id: 1376:AWM73_RS03200
uniprot id: A0A0X8FE41
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1376:AWM73 RS04700
gene id: 1376:AWM73_RS04700
uniprot id: A0A0X8FEQ1
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1376:AWM73 RS01290
gene id: 1376:AWM73_RS01290
uniprot id: A0A109RE15
names: Similarity
messages: Belongs to the CobH/CbiC family.

1376:AWM73 RS07285
gene id: 1376:AWM73_RS07285
uniprot id: A0A0X8FFC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1376:AWM73 RS01025
gene id: 1376:AWM73_RS01025
uniprot id: A0A0X8FD71
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1376:AWM73 RS04455
gene id: 1376:AWM73_RS04455
uniprot id: A0A0X8FEF9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1376:AWM73 RS06910
gene id: 1376:AWM73_RS06910
uniprot id: A0A109REN7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1376:AWM73 RS04230
gene id: 1376:AWM73_RS04230
uniprot id: A0A0X8FEB1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1376:AWM73 RS04745
gene id: 1376:AWM73_RS04745
uniprot id: A0A109REH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1376:AWM73 RS01345
gene id: 1376:AWM73_RS01345
uniprot id: A0A0X8FDA7
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1376:AWM73 RS05135
gene id: 1376:AWM73_RS05135
uniprot id: A0A0X8FEP0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1376:AWM73 RS05220
gene id: 1376:AWM73_RS05220
uniprot id: A0A7T2VRI0
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS08935
gene id: 1376:AWM73_RS08935
uniprot id: A0A109RF02
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1376:AWM73 RS03735
gene id: 1376:AWM73_RS03735
uniprot id: A0A0X8FE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1376:AWM73 RS00450
gene id: 1376:AWM73_RS00450
uniprot id: A0A0X8FD65
names: Similarity
messages: Belongs to the PemK/MazF family.

1376:AWM73 RS00920
gene id: 1376:AWM73_RS00920
uniprot id: A0A0X8FD55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1376:AWM73 RS05960
gene id: 1376:AWM73_RS05960
uniprot id: A0A0X8FEX6
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1376:AWM73 RS03130
gene id: 1376:AWM73_RS03130
uniprot id: A0A0X8FDY2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1376:AWM73 RS08370
gene id: 1376:AWM73_RS08370
uniprot id: A0A109RF61
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1376:AWM73 RS01940
gene id: 1376:AWM73_RS01940
uniprot id: A0A0X8FDI1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1376:AWM73 RS04895
gene id: 1376:AWM73_RS04895
uniprot id: A0A0X8FG54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1376:AWM73 RS01110
gene id: 1376:AWM73_RS01110
uniprot id: A0A109RE89
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1376:AWM73 RS00665
gene id: 1376:AWM73_RS00665
uniprot id: A0A120I9J5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1376:AWM73 RS00195
gene id: 1376:AWM73_RS00195
uniprot id: A0A0X8FD21
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1376:AWM73 RS07990
gene id: 1376:AWM73_RS07990
uniprot id: A0A109REW7
names: Subcellular Location Annotation
messages: Cytoplasm

1376:AWM73 RS02260
gene id: 1376:AWM73_RS02260
uniprot id: A0A0X8FDM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1376:AWM73 RS08380
gene id: 1376:AWM73_RS08380
uniprot id: A0A109RER1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1376:AWM73 RS03785
gene id: 1376:AWM73_RS03785
uniprot id: A0A109REA7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1376:AWM73 RS07970
gene id: 1376:AWM73_RS07970
uniprot id: A0A0X8FFL6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1376:AWM73 RS06335
gene id: 1376:AWM73_RS06335
uniprot id: A0A0X8FF33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1376:AWM73 RS04075
gene id: 1376:AWM73_RS04075
uniprot id: A0A0X8FE81
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1376:AWM73 RS03700
gene id: 1376:AWM73_RS03700
uniprot id: A0A0X8FFQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1376:AWM73 RS07375
gene id: 1376:AWM73_RS07375
uniprot id: A0A7T2RRF6
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS01490
gene id: 1376:AWM73_RS01490
uniprot id: A0A0X8FDD2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1376:AWM73 RS01075
gene id: 1376:AWM73_RS01075
uniprot id: A0A0X8FDE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1376:AWM73 RS07035
gene id: 1376:AWM73_RS07035
uniprot id: A0A0X8FF92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1376:AWM73 RS05215
gene id: 1376:AWM73_RS05215
uniprot id: A0A0X8FEN3
names: Subcellular Location Annotation
messages: Membrane

1376:AWM73 RS08025
gene id: 1376:AWM73_RS08025
uniprot id: A0A0X8FFL5
names: Subcellular Location Annotation
messages: Membrane