13689:I6G65 RS05010
gene id: 13689:I6G65_RS05010
uniprot id: A0A411LHW5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

13689:I6G65 RS14040
gene id: 13689:I6G65_RS14040
uniprot id: A0A411LMF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

13689:I6G65 RS01930
gene id: 13689:I6G65_RS01930
uniprot id: A0A411LG70
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

13689:I6G65 RS17225
gene id: 13689:I6G65_RS17225
uniprot id: A0A411LEP8
names: Similarity
messages: Belongs to the BolA/IbaG family.

13689:I6G65 RS05065
gene id: 13689:I6G65_RS05065
uniprot id: A0A411LHX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

13689:I6G65 RS19785
gene id: 13689:I6G65_RS19785
uniprot id: A0A411LFA7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS13180
gene id: 13689:I6G65_RS13180
uniprot id: A0A411LM48
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS08240
gene id: 13689:I6G65_RS08240
uniprot id: A0A411LJQ7
names: Similarity
messages: Belongs to the YkuD family.

13689:I6G65 RS18035
gene id: 13689:I6G65_RS18035
uniprot id: A0A411LF17
names: Similarity
messages: Belongs to the GST superfamily.

13689:I6G65 RS15105
gene id: 13689:I6G65_RS15105
uniprot id: A0A411LN46
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS09255
gene id: 13689:I6G65_RS09255
uniprot id: A0A411LK90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

13689:I6G65 RS09520
gene id: 13689:I6G65_RS09520
uniprot id: A0A7T3AAW1
names: Similarity
messages: Belongs to the Dps family.

13689:I6G65 RS14805
gene id: 13689:I6G65_RS14805
uniprot id: A0A411LMU7
names: Cofactor
messages: Can also use Mn(2+) ion.

13689:I6G65 RS17830
gene id: 13689:I6G65_RS17830
uniprot id: A0A411LEY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

13689:I6G65 RS10040
gene id: 13689:I6G65_RS10040
uniprot id: A0A411LKS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

13689:I6G65 RS03030
gene id: 13689:I6G65_RS03030
uniprot id: A0A411LGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

13689:I6G65 RS05715
gene id: 13689:I6G65_RS05715
uniprot id: A0A411LIF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

13689:I6G65 RS08390
gene id: 13689:I6G65_RS08390
uniprot id: A0A411LJU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

13689:I6G65 RS00845
gene id: 13689:I6G65_RS00845
uniprot id: A0A7Y2PBP6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS06775
gene id: 13689:I6G65_RS06775
uniprot id: A0A411LIX4
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

13689:I6G65 RS07470
gene id: 13689:I6G65_RS07470
uniprot id: A0A411LJ79
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

13689:I6G65 RS10665
gene id: 13689:I6G65_RS10665
uniprot id: A0A411LKV5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS03390
gene id: 13689:I6G65_RS03390
uniprot id: A0A411LH00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS06200
gene id: 13689:I6G65_RS06200
uniprot id: A0A411LIM9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

13689:I6G65 RS03200
gene id: 13689:I6G65_RS03200
uniprot id: A0A7T3E5C4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

13689:I6G65 RS10510
gene id: 13689:I6G65_RS10510
uniprot id: A0A411LKT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

13689:I6G65 RS06795
gene id: 13689:I6G65_RS06795
uniprot id: A0A411LIV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

13689:I6G65 RS07170
gene id: 13689:I6G65_RS07170
uniprot id: A0A411LJ58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

13689:I6G65 RS12555
gene id: 13689:I6G65_RS12555
uniprot id: A0A411LLT2
names: Similarity
messages: Belongs to the IlvD/Edd family.

13689:I6G65 RS09630
gene id: 13689:I6G65_RS09630
uniprot id: A0A411LKF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

13689:I6G65 RS07500
gene id: 13689:I6G65_RS07500
uniprot id: A0A411LJ90
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

13689:I6G65 RS18205
gene id: 13689:I6G65_RS18205
uniprot id: A0A411LF43
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

13689:I6G65 RS06275
gene id: 13689:I6G65_RS06275
uniprot id: A0A7T3AA18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

13689:I6G65 RS16365
gene id: 13689:I6G65_RS16365
uniprot id: A0A411LEI5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

13689:I6G65 RS13410
gene id: 13689:I6G65_RS13410
uniprot id: A0A411LM44
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

13689:I6G65 RS19225
gene id: 13689:I6G65_RS19225
uniprot id: A0A411LFK3
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

13689:I6G65 RS04620
gene id: 13689:I6G65_RS04620
uniprot id: A0A411LHK9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

13689:I6G65 RS17685
gene id: 13689:I6G65_RS17685
uniprot id: A0A411LEV3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS13580
gene id: 13689:I6G65_RS13580
uniprot id: A0A411LM72
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS05280
gene id: 13689:I6G65_RS05280
uniprot id: A0A411LI17
names: Similarity
messages: Belongs to the AlaDH/PNT family.

13689:I6G65 RS14420
gene id: 13689:I6G65_RS14420
uniprot id: A0A411LMP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

13689:I6G65 RS07045
gene id: 13689:I6G65_RS07045
uniprot id: A0A411LIZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS08505
gene id: 13689:I6G65_RS08505
uniprot id: A0A411LJV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

13689:I6G65 RS08635
gene id: 13689:I6G65_RS08635
uniprot id: A0A411LK00
names: Similarity
messages: Belongs to the ros/MucR family.

13689:I6G65 RS07190
gene id: 13689:I6G65_RS07190
uniprot id: A0A411LJ62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

13689:I6G65 RS15495
gene id: 13689:I6G65_RS15495
uniprot id: A0A411LN64
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

13689:I6G65 RS08650
gene id: 13689:I6G65_RS08650
uniprot id: A0A411LJY6
names: Similarity
messages: Belongs to the MotB family.

13689:I6G65 RS06675
gene id: 13689:I6G65_RS06675
uniprot id: A0A411LIU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

13689:I6G65 RS17180
gene id: 13689:I6G65_RS17180
uniprot id: A0A411LEP0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

13689:I6G65 RS01790
gene id: 13689:I6G65_RS01790
uniprot id: A0A031J266
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

13689:I6G65 RS09815
gene id: 13689:I6G65_RS09815
uniprot id: A0A411LKI1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

13689:I6G65 RS17765
gene id: 13689:I6G65_RS17765
uniprot id: A0A411LNG1
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

13689:I6G65 RS08870
gene id: 13689:I6G65_RS08870
uniprot id: A0A411LK27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

13689:I6G65 RS13115
gene id: 13689:I6G65_RS13115
uniprot id: A0A411LM29
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

13689:I6G65 RS02510
gene id: 13689:I6G65_RS02510
uniprot id: A0A411LGK9
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

13689:I6G65 RS04000
gene id: 13689:I6G65_RS04000
uniprot id: A0A7Y2KP07
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

13689:I6G65 RS02700
gene id: 13689:I6G65_RS02700
uniprot id: A0A411LGT0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

13689:I6G65 RS10830
gene id: 13689:I6G65_RS10830
uniprot id: A0A411LKY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

13689:I6G65 RS09725
gene id: 13689:I6G65_RS09725
uniprot id: A0A411LKG5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

13689:I6G65 RS15655
gene id: 13689:I6G65_RS15655
uniprot id: A0A411LEB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

13689:I6G65 RS16490
gene id: 13689:I6G65_RS16490
uniprot id: A0A7T3A7F7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

13689:I6G65 RS13010
gene id: 13689:I6G65_RS13010
uniprot id: A0A411LM49
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

13689:I6G65 RS11725
gene id: 13689:I6G65_RS11725
uniprot id: A0A411LLD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS06520
gene id: 13689:I6G65_RS06520
uniprot id: A0A411LIQ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS09040
gene id: 13689:I6G65_RS09040
uniprot id: A0A7Y2KRM4
names: Similarity
messages: Belongs to the glutamate synthase family.

13689:I6G65 RS08995
gene id: 13689:I6G65_RS08995
uniprot id: A0A411LK42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

13689:I6G65 RS10205
gene id: 13689:I6G65_RS10205
uniprot id: A0A411LKM5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS13105
gene id: 13689:I6G65_RS13105
uniprot id: A0A411LM02
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

13689:I6G65 RS15040
gene id: 13689:I6G65_RS15040
uniprot id: A0A411LN08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

13689:I6G65 RS19770
gene id: 13689:I6G65_RS19770
uniprot id: A0A411LFA8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

13689:I6G65 RS14120
gene id: 13689:I6G65_RS14120
uniprot id: A0A7T3E6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS18485
gene id: 13689:I6G65_RS18485
uniprot id: A0A411LG33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

13689:I6G65 RS15225
gene id: 13689:I6G65_RS15225
uniprot id: A0A411LN14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

13689:I6G65 RS16655
gene id: 13689:I6G65_RS16655
uniprot id: A0A7T3E3V6
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

13689:I6G65 RS13470
gene id: 13689:I6G65_RS13470
uniprot id: A0A411LM95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

13689:I6G65 RS12935
gene id: 13689:I6G65_RS12935
uniprot id: A0A411LLX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

13689:I6G65 RS08135
gene id: 13689:I6G65_RS08135
uniprot id: A0A411LJR3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

13689:I6G65 RS19485
gene id: 13689:I6G65_RS19485
uniprot id: A0A411LFG6
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

13689:I6G65 RS18845
gene id: 13689:I6G65_RS18845
uniprot id: A0A411LFS3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

13689:I6G65 RS10680
gene id: 13689:I6G65_RS10680
uniprot id: A0A411LKW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

13689:I6G65 RS09955
gene id: 13689:I6G65_RS09955
uniprot id: A0A411LKK5
names: Similarity
messages: Belongs to the YggT family.

13689:I6G65 RS04925
gene id: 13689:I6G65_RS04925
uniprot id: A0A411LHX2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

13689:I6G65 RS11955
gene id: 13689:I6G65_RS11955
uniprot id: A0A411LLN2
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

13689:I6G65 RS09700
gene id: 13689:I6G65_RS09700
uniprot id: A0A411LKG1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS13045
gene id: 13689:I6G65_RS13045
uniprot id: A0A411LLZ3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

13689:I6G65 RS14355
gene id: 13689:I6G65_RS14355
uniprot id: A0A411LMN0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

13689:I6G65 RS05890
gene id: 13689:I6G65_RS05890
uniprot id: A0A411LNW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

13689:I6G65 RS05840
gene id: 13689:I6G65_RS05840
uniprot id: A0A7Y2KSK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS02170
gene id: 13689:I6G65_RS02170
uniprot id: A0A411LG48
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

13689:I6G65 RS10760
gene id: 13689:I6G65_RS10760
uniprot id: A0A411LKX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

13689:I6G65 RS07370
gene id: 13689:I6G65_RS07370
uniprot id: A0A411LJ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

13689:I6G65 RS12260
gene id: 13689:I6G65_RS12260
uniprot id: A0A411LP84
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

13689:I6G65 RS09885
gene id: 13689:I6G65_RS09885
uniprot id: A0A7Y2KUA2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

13689:I6G65 RS12060
gene id: 13689:I6G65_RS12060
uniprot id: A0A411LLK3
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS19800
gene id: 13689:I6G65_RS19800
uniprot id: A0A411LFA5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

13689:I6G65 RS05055
gene id: 13689:I6G65_RS05055
uniprot id: A0A411LHZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS10500
gene id: 13689:I6G65_RS10500
uniprot id: A0A411LKS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

13689:I6G65 RS14840
gene id: 13689:I6G65_RS14840
uniprot id: A0A411LMX1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS08820
gene id: 13689:I6G65_RS08820
uniprot id: A0A411LK16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

13689:I6G65 RS06040
gene id: 13689:I6G65_RS06040
uniprot id: A0A411LIL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

13689:I6G65 RS17010
gene id: 13689:I6G65_RS17010
uniprot id: A0A7Y2KRP6
names: Similarity
messages: Belongs to the peptidase S8 family.

13689:I6G65 RS13540
gene id: 13689:I6G65_RS13540
uniprot id: A0A411LM91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

13689:I6G65 RS19010
gene id: 13689:I6G65_RS19010
uniprot id: A0A411LFM7
names: Similarity
messages: Belongs to the TrpF family.

13689:I6G65 RS18930
gene id: 13689:I6G65_RS18930
uniprot id: A0A411LFR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

13689:I6G65 RS05560
gene id: 13689:I6G65_RS05560
uniprot id: A0A411LID0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

13689:I6G65 RS01240
gene id: 13689:I6G65_RS01240
uniprot id: A0A7T3E954
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS14650
gene id: 13689:I6G65_RS14650
uniprot id: A0A411LMV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS08145
gene id: 13689:I6G65_RS08145
uniprot id: A0A411LJR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS05535
gene id: 13689:I6G65_RS05535
uniprot id: A0A411LI82
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS02230
gene id: 13689:I6G65_RS02230
uniprot id: A0A411LG90
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

13689:I6G65 RS01730
gene id: 13689:I6G65_RS01730
uniprot id: A0A7T3E7S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

13689:I6G65 RS12635
gene id: 13689:I6G65_RS12635
uniprot id: A0A7Y2KRE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS17210
gene id: 13689:I6G65_RS17210
uniprot id: A0A411LEP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

13689:I6G65 RS12045
gene id: 13689:I6G65_RS12045
uniprot id: A0A411LLJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS14075
gene id: 13689:I6G65_RS14075
uniprot id: A0A411LMK0
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

13689:I6G65 RS15760
gene id: 13689:I6G65_RS15760
uniprot id: A0A411LEC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

13689:I6G65 RS02980
gene id: 13689:I6G65_RS02980
uniprot id: A0A411LNM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

13689:I6G65 RS02845
gene id: 13689:I6G65_RS02845
uniprot id: A0A411LGW1
names: Similarity
messages: Belongs to the peptidase M17 family.

13689:I6G65 RS18425
gene id: 13689:I6G65_RS18425
uniprot id: A0A411LFX9
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS17565
gene id: 13689:I6G65_RS17565
uniprot id: A0A411LEU1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

13689:I6G65 RS11855
gene id: 13689:I6G65_RS11855
uniprot id: A0A411LLD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

13689:I6G65 RS13285
gene id: 13689:I6G65_RS13285
uniprot id: A0A411LM97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

13689:I6G65 RS01040
gene id: 13689:I6G65_RS01040
uniprot id: A0A7T3E7B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS11540
gene id: 13689:I6G65_RS11540
uniprot id: A0A7T3E5I6
names: Similarity
messages: Belongs to the CFA/CMAS family.

13689:I6G65 RS18085
gene id: 13689:I6G65_RS18085
uniprot id: A0A411LF23
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

13689:I6G65 RS16495
gene id: 13689:I6G65_RS16495
uniprot id: A0A7T3E396
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

13689:I6G65 RS03455
gene id: 13689:I6G65_RS03455
uniprot id: A0A411LH59
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

13689:I6G65 RS08230
gene id: 13689:I6G65_RS08230
uniprot id: A0A411LJQ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

13689:I6G65 RS12440
gene id: 13689:I6G65_RS12440
uniprot id: A0A411LLR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

13689:I6G65 RS14865
gene id: 13689:I6G65_RS14865
uniprot id: A0A411LMV6
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS07545
gene id: 13689:I6G65_RS07545
uniprot id: A0A7T3AA80
names: Similarity
messages: Belongs to the peptidase S8 family.

13689:I6G65 RS07290
gene id: 13689:I6G65_RS07290
uniprot id: A0A411LJ43
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

13689:I6G65 RS03615
gene id: 13689:I6G65_RS03615
uniprot id: A0A411LH76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

13689:I6G65 RS12420
gene id: 13689:I6G65_RS12420
uniprot id: A0A7T3ADD1
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

13689:I6G65 RS05500
gene id: 13689:I6G65_RS05500
uniprot id: A0A411LI70
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS06975
gene id: 13689:I6G65_RS06975
uniprot id: A0A7Y2KLV4
names: Similarity
messages: Belongs to the peptidase S66 family.

13689:I6G65 RS11550
gene id: 13689:I6G65_RS11550
uniprot id: A0A411LL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

13689:I6G65 RS06080
gene id: 13689:I6G65_RS06080
uniprot id: A0A411LIK8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

13689:I6G65 RS14700
gene id: 13689:I6G65_RS14700
uniprot id: A0A411LMU9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

13689:I6G65 RS01770
gene id: 13689:I6G65_RS01770
uniprot id: A0A031J160
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

13689:I6G65 RS07145
gene id: 13689:I6G65_RS07145
uniprot id: A0A411LJ13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

13689:I6G65 RS13965
gene id: 13689:I6G65_RS13965
uniprot id: A0A411LMH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

13689:I6G65 RS03660
gene id: 13689:I6G65_RS03660
uniprot id: A0A411LH81
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

13689:I6G65 RS09870
gene id: 13689:I6G65_RS09870
uniprot id: A0A411LKJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

13689:I6G65 RS07050
gene id: 13689:I6G65_RS07050
uniprot id: A0A411LJ25
names: Similarity
messages: Belongs to the alanine racemase family.

13689:I6G65 RS06330
gene id: 13689:I6G65_RS06330
uniprot id: A0A411LIM3
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS18815
gene id: 13689:I6G65_RS18815
uniprot id: A0A411LFT0
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

13689:I6G65 RS11470
gene id: 13689:I6G65_RS11470
uniprot id: A0A411LL79
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

13689:I6G65 RS10775
gene id: 13689:I6G65_RS10775
uniprot id: A0A411LKX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

13689:I6G65 RS16305
gene id: 13689:I6G65_RS16305
uniprot id: A0A411LEH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS00070
gene id: 13689:I6G65_RS00070
uniprot id: A0A031JAW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

13689:I6G65 RS08685
gene id: 13689:I6G65_RS08685
uniprot id: A0A411LJZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

13689:I6G65 RS07330
gene id: 13689:I6G65_RS07330
uniprot id: A0A411LJ42
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflK subfamily.

13689:I6G65 RS10755
gene id: 13689:I6G65_RS10755
uniprot id: A0A411LKX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

13689:I6G65 RS10425
gene id: 13689:I6G65_RS10425
uniprot id: A0A411LKQ4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

13689:I6G65 RS17810
gene id: 13689:I6G65_RS17810
uniprot id: A0A411LEX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

13689:I6G65 RS13420
gene id: 13689:I6G65_RS13420
uniprot id: A0A411LM83
names: Similarity
messages: Belongs to the UPF0758 family.

13689:I6G65 RS08755
gene id: 13689:I6G65_RS08755
uniprot id: A0A411LK15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

13689:I6G65 RS19755
gene id: 13689:I6G65_RS19755
uniprot id: A0A411LFA1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS08405
gene id: 13689:I6G65_RS08405
uniprot id: A0A411LJU3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

13689:I6G65 RS18935
gene id: 13689:I6G65_RS18935
uniprot id: A0A411LFQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

13689:I6G65 RS07105
gene id: 13689:I6G65_RS07105
uniprot id: A0A411LJ33
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS05650
gene id: 13689:I6G65_RS05650
uniprot id: A0A411LIC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

13689:I6G65 RS13520
gene id: 13689:I6G65_RS13520
uniprot id: A0A411LMA6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS11930
gene id: 13689:I6G65_RS11930
uniprot id: A0A411LLG5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS00100
gene id: 13689:I6G65_RS00100
uniprot id: A0A7T3E7R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

13689:I6G65 RS12700
gene id: 13689:I6G65_RS12700
uniprot id: A0A411LLW2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

13689:I6G65 RS10640
gene id: 13689:I6G65_RS10640
uniprot id: A0A411LKV7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

13689:I6G65 RS19655
gene id: 13689:I6G65_RS19655
uniprot id: A0A411LFD1
names: Similarity
messages: Belongs to the PhzF family.

13689:I6G65 RS11670
gene id: 13689:I6G65_RS11670
uniprot id: A0A411LLD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

13689:I6G65 RS14415
gene id: 13689:I6G65_RS14415
uniprot id: A0A411LMS6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS12760
gene id: 13689:I6G65_RS12760
uniprot id: A0A411LLV6
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

13689:I6G65 RS06870
gene id: 13689:I6G65_RS06870
uniprot id: A0A411LIZ2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

13689:I6G65 RS03015
gene id: 13689:I6G65_RS03015
uniprot id: A0A411LGV9
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

13689:I6G65 RS13245
gene id: 13689:I6G65_RS13245
uniprot id: A0A411LM16
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

13689:I6G65 RS11260
gene id: 13689:I6G65_RS11260
uniprot id: A0A411LL58
names: Subunit
messages: Homotetramer.

13689:I6G65 RS07165
gene id: 13689:I6G65_RS07165
uniprot id: A0A411LJ12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

13689:I6G65 RS15795
gene id: 13689:I6G65_RS15795
uniprot id: A0A7Y2KTI3
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS05360
gene id: 13689:I6G65_RS05360
uniprot id: A0A411LI79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.

13689:I6G65 RS12910
gene id: 13689:I6G65_RS12910
uniprot id: A0A411LLX9
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

13689:I6G65 RS08375
gene id: 13689:I6G65_RS08375
uniprot id: A0A411LJT5
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS06120
gene id: 13689:I6G65_RS06120
uniprot id: A0A411LIK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

13689:I6G65 RS07295
gene id: 13689:I6G65_RS07295
uniprot id: A0A411LJ72
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

13689:I6G65 RS18630
gene id: 13689:I6G65_RS18630
uniprot id: A0A411LFW1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

13689:I6G65 RS19650
gene id: 13689:I6G65_RS19650
uniprot id: A0A411LNI6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

13689:I6G65 RS10310
gene id: 13689:I6G65_RS10310
uniprot id: A0A411LKP3
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

13689:I6G65 RS13040
gene id: 13689:I6G65_RS13040
uniprot id: A0A411LM22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

13689:I6G65 RS12815
gene id: 13689:I6G65_RS12815
uniprot id: A0A411LLY5
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

13689:I6G65 RS10615
gene id: 13689:I6G65_RS10615
uniprot id: A0A411LKU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

13689:I6G65 RS03540
gene id: 13689:I6G65_RS03540
uniprot id: A0A411LH25
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS02505
gene id: 13689:I6G65_RS02505
uniprot id: A0A411LGG6
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

13689:I6G65 RS05225
gene id: 13689:I6G65_RS05225
uniprot id: A0A411LI18
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

13689:I6G65 RS02860
gene id: 13689:I6G65_RS02860
uniprot id: A0A411LGS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

13689:I6G65 RS03340
gene id: 13689:I6G65_RS03340
uniprot id: A0A411LGZ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS06710
gene id: 13689:I6G65_RS06710
uniprot id: A0A411LIS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

13689:I6G65 RS01140
gene id: 13689:I6G65_RS01140
uniprot id: A0A7T3E7W5
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

13689:I6G65 RS05645
gene id: 13689:I6G65_RS05645
uniprot id: A0A411LI87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

13689:I6G65 RS18145
gene id: 13689:I6G65_RS18145
uniprot id: A0A411LF33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

13689:I6G65 RS15790
gene id: 13689:I6G65_RS15790
uniprot id: A0A411LEE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

13689:I6G65 RS14870
gene id: 13689:I6G65_RS14870
uniprot id: A0A411LMV9
names: Similarity
messages: Belongs to the hyi family.

13689:I6G65 RS13455
gene id: 13689:I6G65_RS13455
uniprot id: A0A411LM94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

13689:I6G65 RS18475
gene id: 13689:I6G65_RS18475
uniprot id: A0A411LNI2
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

13689:I6G65 RS08830
gene id: 13689:I6G65_RS08830
uniprot id: A0A411LK19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS02995
gene id: 13689:I6G65_RS02995
uniprot id: A0A411LGY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

13689:I6G65 RS16675
gene id: 13689:I6G65_RS16675
uniprot id: A0A7T3A7H0
names: Similarity
messages: Belongs to the hyi family.

13689:I6G65 RS15475
gene id: 13689:I6G65_RS15475
uniprot id: A0A411LN80
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

13689:I6G65 RS02225
gene id: 13689:I6G65_RS02225
uniprot id: A0A411LG80
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

13689:I6G65 RS18975
gene id: 13689:I6G65_RS18975
uniprot id: A0A411LFP5
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

13689:I6G65 RS17900
gene id: 13689:I6G65_RS17900
uniprot id: A0A411LEZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

13689:I6G65 RS09780
gene id: 13689:I6G65_RS09780
uniprot id: A0A411LKJ4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS19265
gene id: 13689:I6G65_RS19265
uniprot id: A0A7T3A803
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS18780
gene id: 13689:I6G65_RS18780
uniprot id: A0A411LFT5
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

13689:I6G65 RS08975
gene id: 13689:I6G65_RS08975
uniprot id: A0A7T3E635
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

13689:I6G65 RS12800
gene id: 13689:I6G65_RS12800
uniprot id: A0A411LPA8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

13689:I6G65 RS17635
gene id: 13689:I6G65_RS17635
uniprot id: A0A411LEV1
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS02350
gene id: 13689:I6G65_RS02350
uniprot id: A0A411LGH6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

13689:I6G65 RS09565
gene id: 13689:I6G65_RS09565
uniprot id: A0A411LKE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

13689:I6G65 RS09540
gene id: 13689:I6G65_RS09540
uniprot id: A0A411LKF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS17590
gene id: 13689:I6G65_RS17590
uniprot id: A0A411LND3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS08260
gene id: 13689:I6G65_RS08260
uniprot id: A0A411LJS9
names: Subunit
messages: Homodimer.

13689:I6G65 RS15255
gene id: 13689:I6G65_RS15255
uniprot id: A0A411LN47
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

13689:I6G65 RS14085
gene id: 13689:I6G65_RS14085
uniprot id: A0A411LMN1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

13689:I6G65 RS09475
gene id: 13689:I6G65_RS09475
uniprot id: A0A411LKC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

13689:I6G65 RS08855
gene id: 13689:I6G65_RS08855
uniprot id: A0A411LK40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

13689:I6G65 RS09025
gene id: 13689:I6G65_RS09025
uniprot id: A0A411LK46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

13689:I6G65 RS02130
gene id: 13689:I6G65_RS02130
uniprot id: A0A411LG72
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

13689:I6G65 RS17945
gene id: 13689:I6G65_RS17945
uniprot id: A0A411LF01
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

13689:I6G65 RS02370
gene id: 13689:I6G65_RS02370
uniprot id: A0A411LNN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

13689:I6G65 RS10930
gene id: 13689:I6G65_RS10930
uniprot id: A0A411LKZ6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS13710
gene id: 13689:I6G65_RS13710
uniprot id: A0A411LMC5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

13689:I6G65 RS13970
gene id: 13689:I6G65_RS13970
uniprot id: A0A411LMK5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

13689:I6G65 RS00975
gene id: 13689:I6G65_RS00975
uniprot id: A0A7T3AEB8
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS13530
gene id: 13689:I6G65_RS13530
uniprot id: A0A7T3E757
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

13689:I6G65 RS10685
gene id: 13689:I6G65_RS10685
uniprot id: A0A411LL23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

13689:I6G65 RS00540
gene id: 13689:I6G65_RS00540
uniprot id: A0A7Y2PB97
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS14435
gene id: 13689:I6G65_RS14435
uniprot id: A0A411LMQ9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

13689:I6G65 RS13900
gene id: 13689:I6G65_RS13900
uniprot id: A0A411LMF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

13689:I6G65 RS12705
gene id: 13689:I6G65_RS12705
uniprot id: A0A411LLS9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

13689:I6G65 RS15455
gene id: 13689:I6G65_RS15455
uniprot id: A0A411LN77
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

13689:I6G65 RS08215
gene id: 13689:I6G65_RS08215
uniprot id: A0A411LJR4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

13689:I6G65 RS09875
gene id: 13689:I6G65_RS09875
uniprot id: A0A411LP48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

13689:I6G65 RS19295
gene id: 13689:I6G65_RS19295
uniprot id: A0A411LFI9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

13689:I6G65 RS05790
gene id: 13689:I6G65_RS05790
uniprot id: A0A411LIG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

13689:I6G65 RS12820
gene id: 13689:I6G65_RS12820
uniprot id: A0A411LLV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS08310
gene id: 13689:I6G65_RS08310
uniprot id: A0A411LJS5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

13689:I6G65 RS09185
gene id: 13689:I6G65_RS09185
uniprot id: A0A411LK83
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

13689:I6G65 RS10475
gene id: 13689:I6G65_RS10475
uniprot id: A0A411LKR9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

13689:I6G65 RS05390
gene id: 13689:I6G65_RS05390
uniprot id: A0A411LI52
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

13689:I6G65 RS13350
gene id: 13689:I6G65_RS13350
uniprot id: A0A411LM34
names: Subunit
messages: Homodimer.

13689:I6G65 RS15565
gene id: 13689:I6G65_RS15565
uniprot id: A0A411LE58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

13689:I6G65 RS00235
gene id: 13689:I6G65_RS00235
uniprot id: A0A7T3ADY2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

13689:I6G65 RS09205
gene id: 13689:I6G65_RS09205
uniprot id: A0A411LK76
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

13689:I6G65 RS10070
gene id: 13689:I6G65_RS10070
uniprot id: A0A7T3AB33
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

13689:I6G65 RS03550
gene id: 13689:I6G65_RS03550
uniprot id: A0A411LH66
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

13689:I6G65 RS14795
gene id: 13689:I6G65_RS14795
uniprot id: A0A411LMZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

13689:I6G65 RS09380
gene id: 13689:I6G65_RS09380
uniprot id: A0A7Y2KTC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

13689:I6G65 RS15130
gene id: 13689:I6G65_RS15130
uniprot id: A0A411LN28
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

13689:I6G65 RS06915
gene id: 13689:I6G65_RS06915
uniprot id: A0A411LIZ0
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS08665
gene id: 13689:I6G65_RS08665
uniprot id: A0A411LJX7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

13689:I6G65 RS06125
gene id: 13689:I6G65_RS06125
uniprot id: A0A411LIJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

13689:I6G65 RS02360
gene id: 13689:I6G65_RS02360
uniprot id: A0A411LGD7
names: Similarity
messages: Belongs to the Skp family.

13689:I6G65 RS07620
gene id: 13689:I6G65_RS07620
uniprot id: A0A7Y2PE33
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS09750
gene id: 13689:I6G65_RS09750
uniprot id: A0A411LKF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

13689:I6G65 RS12295
gene id: 13689:I6G65_RS12295
uniprot id: A0A411LLT9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS02165
gene id: 13689:I6G65_RS02165
uniprot id: A0A411LGA6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

13689:I6G65 RS10075
gene id: 13689:I6G65_RS10075
uniprot id: A0A411LKL2
names: Similarity
messages: Belongs to the acylphosphatase family.

13689:I6G65 RS08380
gene id: 13689:I6G65_RS08380
uniprot id: A0A411LJV3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

13689:I6G65 RS17410
gene id: 13689:I6G65_RS17410
uniprot id: A0A411LES5
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS05075
gene id: 13689:I6G65_RS05075
uniprot id: A0A411LI30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

13689:I6G65 RS18545
gene id: 13689:I6G65_RS18545
uniprot id: A0A411LFV5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

13689:I6G65 RS00960
gene id: 13689:I6G65_RS00960
uniprot id: A0A7T3AGM2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

13689:I6G65 RS05525
gene id: 13689:I6G65_RS05525
uniprot id: A0A411LIB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

13689:I6G65 RS13450
gene id: 13689:I6G65_RS13450
uniprot id: A0A411LMC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

13689:I6G65 RS16795
gene id: 13689:I6G65_RS16795
uniprot id: A0A7T3A7J4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

13689:I6G65 RS19205
gene id: 13689:I6G65_RS19205
uniprot id: A0A411LFL0
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS09500
gene id: 13689:I6G65_RS09500
uniprot id: A0A411LKC4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS02400
gene id: 13689:I6G65_RS02400
uniprot id: A0A411LGJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

13689:I6G65 RS05180
gene id: 13689:I6G65_RS05180
uniprot id: A0A411LI55
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

13689:I6G65 RS04995
gene id: 13689:I6G65_RS04995
uniprot id: A0A411LI04
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

13689:I6G65 RS10065
gene id: 13689:I6G65_RS10065
uniprot id: A0A411LKL0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

13689:I6G65 RS14550
gene id: 13689:I6G65_RS14550
uniprot id: A0A411LMU8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

13689:I6G65 RS12925
gene id: 13689:I6G65_RS12925
uniprot id: A0A411LLZ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

13689:I6G65 RS18245
gene id: 13689:I6G65_RS18245
uniprot id: A0A411LF68
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

13689:I6G65 RS18850
gene id: 13689:I6G65_RS18850
uniprot id: A0A411LFR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

13689:I6G65 RS08960
gene id: 13689:I6G65_RS08960
uniprot id: A0A411LK39
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

13689:I6G65 RS11850
gene id: 13689:I6G65_RS11850
uniprot id: A0A411LLG3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

13689:I6G65 RS13565
gene id: 13689:I6G65_RS13565
uniprot id: A0A411LMB6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS09965
gene id: 13689:I6G65_RS09965
uniprot id: A0A411LKM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

13689:I6G65 RS18585
gene id: 13689:I6G65_RS18585
uniprot id: A0A411LFX5
names: Similarity
messages: Belongs to the peptidase M13 family.

13689:I6G65 RS07940
gene id: 13689:I6G65_RS07940
uniprot id: A0A411LJL1
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

13689:I6G65 RS13355
gene id: 13689:I6G65_RS13355
uniprot id: A0A411LM73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

13689:I6G65 RS16400
gene id: 13689:I6G65_RS16400
uniprot id: A0A411LEJ3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

13689:I6G65 RS08580
gene id: 13689:I6G65_RS08580
uniprot id: A0A411LJZ1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

13689:I6G65 RS11600
gene id: 13689:I6G65_RS11600
uniprot id: A0A411LL93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

13689:I6G65 RS19490
gene id: 13689:I6G65_RS19490
uniprot id: A0A411LFF2
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS06680
gene id: 13689:I6G65_RS06680
uniprot id: A0A411LIT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

13689:I6G65 RS17800
gene id: 13689:I6G65_RS17800
uniprot id: A0A411LEX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

13689:I6G65 RS15490
gene id: 13689:I6G65_RS15490
uniprot id: A0A411LN54
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

13689:I6G65 RS05880
gene id: 13689:I6G65_RS05880
uniprot id: A0A411LIM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

13689:I6G65 RS05870
gene id: 13689:I6G65_RS05870
uniprot id: A0A411LII7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

13689:I6G65 RS12470
gene id: 13689:I6G65_RS12470
uniprot id: A0A411LLW6
names: Caution
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS07810
gene id: 13689:I6G65_RS07810
uniprot id: A0A411LJI7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS06540
gene id: 13689:I6G65_RS06540
uniprot id: A0A411LIX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

13689:I6G65 RS10595
gene id: 13689:I6G65_RS10595
uniprot id: A0A411LKT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

13689:I6G65 RS17235
gene id: 13689:I6G65_RS17235
uniprot id: A0A411LEP3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

13689:I6G65 RS02495
gene id: 13689:I6G65_RS02495
uniprot id: A0A411LGH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

13689:I6G65 RS08015
gene id: 13689:I6G65_RS08015
uniprot id: A0A411LJM0
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

13689:I6G65 RS06940
gene id: 13689:I6G65_RS06940
uniprot id: A0A411LJ02
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

13689:I6G65 RS05995
gene id: 13689:I6G65_RS05995
uniprot id: A0A411LNS6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

13689:I6G65 RS03040
gene id: 13689:I6G65_RS03040
uniprot id: A0A411LNP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

13689:I6G65 RS04965
gene id: 13689:I6G65_RS04965
uniprot id: A0A411LI73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

13689:I6G65 RS18625
gene id: 13689:I6G65_RS18625
uniprot id: A0A411LFX0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

13689:I6G65 RS02795
gene id: 13689:I6G65_RS02795
uniprot id: A0A411LGQ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS19170
gene id: 13689:I6G65_RS19170
uniprot id: A0A411LFL5
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS05580
gene id: 13689:I6G65_RS05580
uniprot id: A0A411LIC5
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

13689:I6G65 RS02060
gene id: 13689:I6G65_RS02060
uniprot id: A0A411LG50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

13689:I6G65 RS05725
gene id: 13689:I6G65_RS05725
uniprot id: A0A411LIK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

13689:I6G65 RS03435
gene id: 13689:I6G65_RS03435
uniprot id: A0A7T3A8L4
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

13689:I6G65 RS07965
gene id: 13689:I6G65_RS07965
uniprot id: A0A411LJL4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

13689:I6G65 RS19380
gene id: 13689:I6G65_RS19380
uniprot id: A0A411LFH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS12035
gene id: 13689:I6G65_RS12035
uniprot id: A0A411LLI4
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS19215
gene id: 13689:I6G65_RS19215
uniprot id: A0A411LFK2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

13689:I6G65 RS18295
gene id: 13689:I6G65_RS18295
uniprot id: A0A411LF79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

13689:I6G65 RS15705
gene id: 13689:I6G65_RS15705
uniprot id: A0A411LN98
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS06185
gene id: 13689:I6G65_RS06185
uniprot id: A0A7T3ABY5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

13689:I6G65 RS13140
gene id: 13689:I6G65_RS13140
uniprot id: A0A411LLZ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

13689:I6G65 RS11885
gene id: 13689:I6G65_RS11885
uniprot id: A0A411LLE2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

13689:I6G65 RS00980
gene id: 13689:I6G65_RS00980
uniprot id: A0A7T3AEF7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS05960
gene id: 13689:I6G65_RS05960
uniprot id: A0A411LIG0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

13689:I6G65 RS05630
gene id: 13689:I6G65_RS05630
uniprot id: A0A411LID6
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS05370
gene id: 13689:I6G65_RS05370
uniprot id: A0A411LI64
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

13689:I6G65 RS06640
gene id: 13689:I6G65_RS06640
uniprot id: A0A411LIW7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

13689:I6G65 RS15780
gene id: 13689:I6G65_RS15780
uniprot id: A0A411LED9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

13689:I6G65 RS18060
gene id: 13689:I6G65_RS18060
uniprot id: A0A411LF38
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

13689:I6G65 RS10260
gene id: 13689:I6G65_RS10260
uniprot id: A0A411LKN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

13689:I6G65 RS10330
gene id: 13689:I6G65_RS10330
uniprot id: A0A411LKP2
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

13689:I6G65 RS02305
gene id: 13689:I6G65_RS02305
uniprot id: A0A411LGE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS06820
gene id: 13689:I6G65_RS06820
uniprot id: A0A411LIZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

13689:I6G65 RS10530
gene id: 13689:I6G65_RS10530
uniprot id: A0A411LP42
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS18580
gene id: 13689:I6G65_RS18580
uniprot id: A0A411LFX1
names: Similarity
messages: Belongs to the peptidase M13 family.

13689:I6G65 RS17300
gene id: 13689:I6G65_RS17300
uniprot id: A0A411LEW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

13689:I6G65 RS00085
gene id: 13689:I6G65_RS00085
uniprot id: A0A7T3E759
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

13689:I6G65 RS19570
gene id: 13689:I6G65_RS19570
uniprot id: A0A411LFJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

13689:I6G65 RS12095
gene id: 13689:I6G65_RS12095
uniprot id: A0A411LLK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

13689:I6G65 RS13095
gene id: 13689:I6G65_RS13095
uniprot id: A0A411LM26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

13689:I6G65 RS09790
gene id: 13689:I6G65_RS09790
uniprot id: A0A411LKH7
names: Similarity
messages: Belongs to the SCO1/2 family.

13689:I6G65 RS03005
gene id: 13689:I6G65_RS03005
uniprot id: A0A411LGU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

13689:I6G65 RS08715
gene id: 13689:I6G65_RS08715
uniprot id: A0A411LJZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

13689:I6G65 RS11125
gene id: 13689:I6G65_RS11125
uniprot id: A0A411LL92
names: Caution
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS12430
gene id: 13689:I6G65_RS12430
uniprot id: A0A7T3ABZ7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

13689:I6G65 RS03150
gene id: 13689:I6G65_RS03150
uniprot id: A0A411LGY8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

13689:I6G65 RS07730
gene id: 13689:I6G65_RS07730
uniprot id: A0A411LJC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

13689:I6G65 RS05845
gene id: 13689:I6G65_RS05845
uniprot id: A0A411LIF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS09320
gene id: 13689:I6G65_RS09320
uniprot id: A0A411LKA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

13689:I6G65 RS13270
gene id: 13689:I6G65_RS13270
uniprot id: A0A411LM47
names: Caution
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS08690
gene id: 13689:I6G65_RS08690
uniprot id: A0A411LK10
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

13689:I6G65 RS17185
gene id: 13689:I6G65_RS17185
uniprot id: A0A411LEN4
names: Similarity
messages: Belongs to the TPP enzyme family.

13689:I6G65 RS10255
gene id: 13689:I6G65_RS10255
uniprot id: A0A411LKN4
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

13689:I6G65 RS06085
gene id: 13689:I6G65_RS06085
uniprot id: A0A411LII3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

13689:I6G65 RS13185
gene id: 13689:I6G65_RS13185
uniprot id: A0A411LM32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS05585
gene id: 13689:I6G65_RS05585
uniprot id: A0A411LIA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

13689:I6G65 RS13700
gene id: 13689:I6G65_RS13700
uniprot id: A0A7Y2KNN0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

13689:I6G65 RS10320
gene id: 13689:I6G65_RS10320
uniprot id: A0A411LKP5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS18730
gene id: 13689:I6G65_RS18730
uniprot id: A0A411LFT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

13689:I6G65 RS07535
gene id: 13689:I6G65_RS07535
uniprot id: A0A411LJ92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

13689:I6G65 RS17955
gene id: 13689:I6G65_RS17955
uniprot id: A0A411LF09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

13689:I6G65 RS02910
gene id: 13689:I6G65_RS02910
uniprot id: A0A411LGY4
names: Similarity
messages: Belongs to the citrate synthase family.

13689:I6G65 RS18365
gene id: 13689:I6G65_RS18365
uniprot id: A0A411LF88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

13689:I6G65 RS15465
gene id: 13689:I6G65_RS15465
uniprot id: A0A411LN16
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

13689:I6G65 RS19210
gene id: 13689:I6G65_RS19210
uniprot id: A0A411LFL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

13689:I6G65 RS11410
gene id: 13689:I6G65_RS11410
uniprot id: A0A411LL63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

13689:I6G65 RS14425
gene id: 13689:I6G65_RS14425
uniprot id: A0A411LMN9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

13689:I6G65 RS10980
gene id: 13689:I6G65_RS10980
uniprot id: A0A411LL07
names: Caution
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS13655
gene id: 13689:I6G65_RS13655
uniprot id: A0A7Y2PBH7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

13689:I6G65 RS15570
gene id: 13689:I6G65_RS15570
uniprot id: A0A411LE55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

13689:I6G65 RS14370
gene id: 13689:I6G65_RS14370
uniprot id: A0A411LPB7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

13689:I6G65 RS17825
gene id: 13689:I6G65_RS17825
uniprot id: A0A411LEY4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

13689:I6G65 RS09360
gene id: 13689:I6G65_RS09360
uniprot id: A0A411LKA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

13689:I6G65 RS10675
gene id: 13689:I6G65_RS10675
uniprot id: A0A411LKV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

13689:I6G65 RS09910
gene id: 13689:I6G65_RS09910
uniprot id: A0A7Y2KTQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

13689:I6G65 RS01230
gene id: 13689:I6G65_RS01230
uniprot id: A0A7T3AE77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

13689:I6G65 RS18740
gene id: 13689:I6G65_RS18740
uniprot id: A0A411LNI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

13689:I6G65 RS02585
gene id: 13689:I6G65_RS02585
uniprot id: A0A7Y2PCG9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS06810
gene id: 13689:I6G65_RS06810
uniprot id: A0A411LNY8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

13689:I6G65 RS19145
gene id: 13689:I6G65_RS19145
uniprot id: A0A411LFL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

13689:I6G65 RS11570
gene id: 13689:I6G65_RS11570
uniprot id: A0A411LLA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS10550
gene id: 13689:I6G65_RS10550
uniprot id: A0A411LKT0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

13689:I6G65 RS10060
gene id: 13689:I6G65_RS10060
uniprot id: A0A411LKL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

13689:I6G65 RS14810
gene id: 13689:I6G65_RS14810
uniprot id: A0A7T3E8G2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

13689:I6G65 RS04400
gene id: 13689:I6G65_RS04400
uniprot id: A0A411LHI4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

13689:I6G65 RS09435
gene id: 13689:I6G65_RS09435
uniprot id: A0A411LKB4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS06355
gene id: 13689:I6G65_RS06355
uniprot id: A0A411LIR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

13689:I6G65 RS13375
gene id: 13689:I6G65_RS13375
uniprot id: A0A411LM56
names: Cofactor
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

13689:I6G65 RS18710
gene id: 13689:I6G65_RS18710
uniprot id: A0A411LFZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

13689:I6G65 RS19535
gene id: 13689:I6G65_RS19535
uniprot id: A0A411LFE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

13689:I6G65 RS18370
gene id: 13689:I6G65_RS18370
uniprot id: A0A411LF73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

13689:I6G65 RS05255
gene id: 13689:I6G65_RS05255
uniprot id: A0A411LIB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

13689:I6G65 RS12695
gene id: 13689:I6G65_RS12695
uniprot id: A0A411LLV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

13689:I6G65 RS18695
gene id: 13689:I6G65_RS18695
uniprot id: A0A411LFU9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

13689:I6G65 RS17895
gene id: 13689:I6G65_RS17895
uniprot id: A0A411LEZ7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

13689:I6G65 RS09945
gene id: 13689:I6G65_RS09945
uniprot id: A0A411LKJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

13689:I6G65 RS14175
gene id: 13689:I6G65_RS14175
uniprot id: A0A411LMN6
names: Similarity
messages: Belongs to the Lgt family.

13689:I6G65 RS19560
gene id: 13689:I6G65_RS19560
uniprot id: A0A411LFE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

13689:I6G65 RS00020
gene id: 13689:I6G65_RS00020
uniprot id: A0A7T3E8A3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

13689:I6G65 RS16455
gene id: 13689:I6G65_RS16455
uniprot id: A0A7T3A6Z0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

13689:I6G65 RS11875
gene id: 13689:I6G65_RS11875
uniprot id: A0A7Y2KQS1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS04390
gene id: 13689:I6G65_RS04390
uniprot id: A0A411LHH0
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.

13689:I6G65 RS18045
gene id: 13689:I6G65_RS18045
uniprot id: A0A411LF75
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS08705
gene id: 13689:I6G65_RS08705
uniprot id: A0A411LJZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

13689:I6G65 RS08320
gene id: 13689:I6G65_RS08320
uniprot id: A0A411LJS7
names: Similarity
messages: Belongs to the BolA/IbaG family.

13689:I6G65 RS13485
gene id: 13689:I6G65_RS13485
uniprot id: A0A411LM80
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS08250
gene id: 13689:I6G65_RS08250
uniprot id: A0A411LJT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

13689:I6G65 RS15825
gene id: 13689:I6G65_RS15825
uniprot id: A0A411LEF0
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

13689:I6G65 RS18520
gene id: 13689:I6G65_RS18520
uniprot id: A0A411LFY2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

13689:I6G65 RS08700
gene id: 13689:I6G65_RS08700
uniprot id: A0A411LK05
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

13689:I6G65 RS01620
gene id: 13689:I6G65_RS01620
uniprot id: A0A7T3AE66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.

13689:I6G65 RS05480
gene id: 13689:I6G65_RS05480
uniprot id: A0A411LI84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

13689:I6G65 RS15060
gene id: 13689:I6G65_RS15060
uniprot id: A0A411LMZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

13689:I6G65 RS19420
gene id: 13689:I6G65_RS19420
uniprot id: A0A411LFG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

13689:I6G65 RS06740
gene id: 13689:I6G65_RS06740
uniprot id: A0A411LIU0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

13689:I6G65 RS06950
gene id: 13689:I6G65_RS06950
uniprot id: A0A411LJ16
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

13689:I6G65 RS07950
gene id: 13689:I6G65_RS07950
uniprot id: A0A411LJK9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

13689:I6G65 RS19575
gene id: 13689:I6G65_RS19575
uniprot id: A0A411LFC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

13689:I6G65 RS04700
gene id: 13689:I6G65_RS04700
uniprot id: A0A7Y2KRT2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS02745
gene id: 13689:I6G65_RS02745
uniprot id: A0A411LGP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

13689:I6G65 RS10460
gene id: 13689:I6G65_RS10460
uniprot id: A0A411LKY3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

13689:I6G65 RS15665
gene id: 13689:I6G65_RS15665
uniprot id: A0A7Y2KTM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS07510
gene id: 13689:I6G65_RS07510
uniprot id: A0A411LJB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS09495
gene id: 13689:I6G65_RS09495
uniprot id: A0A411LKD5
names: Similarity
messages: Belongs to the AAA ATPase family.

13689:I6G65 RS02320
gene id: 13689:I6G65_RS02320
uniprot id: A0A7Y2KPM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

13689:I6G65 RS13740
gene id: 13689:I6G65_RS13740
uniprot id: A0A411LME0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

13689:I6G65 RS13845
gene id: 13689:I6G65_RS13845
uniprot id: A0A411LME3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

13689:I6G65 RS00120
gene id: 13689:I6G65_RS00120
uniprot id: A0A7T3AE56
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

13689:I6G65 RS01000
gene id: 13689:I6G65_RS01000
uniprot id: A0A7T3E7F0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

13689:I6G65 RS08255
gene id: 13689:I6G65_RS08255
uniprot id: A0A411LJR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

13689:I6G65 RS13820
gene id: 13689:I6G65_RS13820
uniprot id: A0A411LMG2
names: Similarity
messages: Belongs to the GSP E family.

13689:I6G65 RS01415
gene id: 13689:I6G65_RS01415
uniprot id: A0A7T3E941
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

13689:I6G65 RS03565
gene id: 13689:I6G65_RS03565
uniprot id: A0A7T3A8T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

13689:I6G65 RS18265
gene id: 13689:I6G65_RS18265
uniprot id: A0A411LF53
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

13689:I6G65 RS09975
gene id: 13689:I6G65_RS09975
uniprot id: A0A411LKK6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

13689:I6G65 RS13030
gene id: 13689:I6G65_RS13030
uniprot id: A0A411LM14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

13689:I6G65 RS19860
gene id: 13689:I6G65_RS19860
uniprot id: A0A411LNF7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

13689:I6G65 RS18765
gene id: 13689:I6G65_RS18765
uniprot id: A0A7T3A7P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

13689:I6G65 RS04980
gene id: 13689:I6G65_RS04980
uniprot id: A0A411LHZ1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS06090
gene id: 13689:I6G65_RS06090
uniprot id: A0A411LIM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

13689:I6G65 RS03970
gene id: 13689:I6G65_RS03970
uniprot id: A0A411LHF3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS03620
gene id: 13689:I6G65_RS03620
uniprot id: A0A411LNM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

13689:I6G65 RS19040
gene id: 13689:I6G65_RS19040
uniprot id: A0A411LFN9
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS11315
gene id: 13689:I6G65_RS11315
uniprot id: A0A411LL60
names: Similarity
messages: Belongs to the peptidase M24B family.

13689:I6G65 RS05665
gene id: 13689:I6G65_RS05665
uniprot id: A0A411LI91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

13689:I6G65 RS18805
gene id: 13689:I6G65_RS18805
uniprot id: A0A411LFT8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

13689:I6G65 RS19105
gene id: 13689:I6G65_RS19105
uniprot id: A0A411LFM5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

13689:I6G65 RS07040
gene id: 13689:I6G65_RS07040
uniprot id: A0A411LIZ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

13689:I6G65 RS11120
gene id: 13689:I6G65_RS11120
uniprot id: A0A411LL35
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS06015
gene id: 13689:I6G65_RS06015
uniprot id: A0A411LII4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: With S4 and S12 plays an important role in translational accuracy.

13689:I6G65 RS15155
gene id: 13689:I6G65_RS15155
uniprot id: A0A7T3AD02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS06105
gene id: 13689:I6G65_RS06105
uniprot id: A0A411LIM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

13689:I6G65 RS05765
gene id: 13689:I6G65_RS05765
uniprot id: A0A411LIB7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS19340
gene id: 13689:I6G65_RS19340
uniprot id: A0A411LFN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

13689:I6G65 RS10340
gene id: 13689:I6G65_RS10340
uniprot id: A0A411LKQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

13689:I6G65 RS11595
gene id: 13689:I6G65_RS11595
uniprot id: A0A411LLB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

13689:I6G65 RS06095
gene id: 13689:I6G65_RS06095
uniprot id: A0A411LIH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

13689:I6G65 RS05640
gene id: 13689:I6G65_RS05640
uniprot id: A0A411LIA3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

13689:I6G65 RS07740
gene id: 13689:I6G65_RS07740
uniprot id: A0A411LJC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

13689:I6G65 RS18480
gene id: 13689:I6G65_RS18480
uniprot id: A0A411LFW9
names: Similarity
messages: Belongs to the ArsC family.

13689:I6G65 RS12350
gene id: 13689:I6G65_RS12350
uniprot id: A0A411LLU9
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS09720
gene id: 13689:I6G65_RS09720
uniprot id: A0A411LKI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

13689:I6G65 RS14500
gene id: 13689:I6G65_RS14500
uniprot id: A0A411LMV3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

13689:I6G65 RS02040
gene id: 13689:I6G65_RS02040
uniprot id: A0A411LG22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

13689:I6G65 RS06650
gene id: 13689:I6G65_RS06650
uniprot id: A0A411LJ00
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

13689:I6G65 RS01405
gene id: 13689:I6G65_RS01405
uniprot id: A0A7T3AE60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

13689:I6G65 RS02685
gene id: 13689:I6G65_RS02685
uniprot id: A0A411LGU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

13689:I6G65 RS06455
gene id: 13689:I6G65_RS06455
uniprot id: A0A411LIT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

13689:I6G65 RS12780
gene id: 13689:I6G65_RS12780
uniprot id: A0A411LLY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

13689:I6G65 RS07465
gene id: 13689:I6G65_RS07465
uniprot id: A0A411LJB1
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

13689:I6G65 RS13940
gene id: 13689:I6G65_RS13940
uniprot id: A0A411LMI3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

13689:I6G65 RS17140
gene id: 13689:I6G65_RS17140
uniprot id: A0A7Y2PF12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS03180
gene id: 13689:I6G65_RS03180
uniprot id: A0A411LH07
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS03120
gene id: 13689:I6G65_RS03120
uniprot id: A0A411LGW5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

13689:I6G65 RS16245
gene id: 13689:I6G65_RS16245
uniprot id: A0A411LEL9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS14460
gene id: 13689:I6G65_RS14460
uniprot id: A0A411LMK6
names: Similarity
messages: Belongs to the DEAD box helicase family.

13689:I6G65 RS19845
gene id: 13689:I6G65_RS19845
uniprot id: A0A411LFA9
names: Similarity
messages: Belongs to the ArsC family.

13689:I6G65 RS03710
gene id: 13689:I6G65_RS03710
uniprot id: A0A411LH54
names: Similarity
messages: Belongs to the SufE family.

13689:I6G65 RS08305
gene id: 13689:I6G65_RS08305
uniprot id: A0A411LJR7
names: Similarity
messages: Belongs to the pirin family.

13689:I6G65 RS17850
gene id: 13689:I6G65_RS17850
uniprot id: A0A411LEY9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

13689:I6G65 RS19700
gene id: 13689:I6G65_RS19700
uniprot id: A0A411LFH8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS02600
gene id: 13689:I6G65_RS02600
uniprot id: A0A411LGN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

13689:I6G65 RS03420
gene id: 13689:I6G65_RS03420
uniprot id: A0A411LH01
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

13689:I6G65 RS05545
gene id: 13689:I6G65_RS05545
uniprot id: A0A411LI68
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

13689:I6G65 RS11490
gene id: 13689:I6G65_RS11490
uniprot id: A0A411LL76
names: Similarity
messages: Belongs to the LOG family.

13689:I6G65 RS01575
gene id: 13689:I6G65_RS01575
uniprot id: A0A7T3AFP3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

13689:I6G65 RS15525
gene id: 13689:I6G65_RS15525
uniprot id: A0A411LN81
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS07970
gene id: 13689:I6G65_RS07970
uniprot id: A0A411LJM7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

13689:I6G65 RS16320
gene id: 13689:I6G65_RS16320
uniprot id: A0A411LEI8
names: Similarity
messages: Belongs to the GcvT family.

13689:I6G65 RS01320
gene id: 13689:I6G65_RS01320
uniprot id: A0A7T3AE69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

13689:I6G65 RS13650
gene id: 13689:I6G65_RS13650
uniprot id: A0A411LMC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS07475
gene id: 13689:I6G65_RS07475
uniprot id: A0A411LJA6
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS01315
gene id: 13689:I6G65_RS01315
uniprot id: A0A7T3E7V6
names: Similarity
messages: Belongs to the FrmR/RcnR family.

13689:I6G65 RS02890
gene id: 13689:I6G65_RS02890
uniprot id: A0A411LGS9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

13689:I6G65 RS02005
gene id: 13689:I6G65_RS02005
uniprot id: A0A411LG47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

13689:I6G65 RS08545
gene id: 13689:I6G65_RS08545
uniprot id: A0A411LJY0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

13689:I6G65 RS04895
gene id: 13689:I6G65_RS04895
uniprot id: A0A411LI03
names: Similarity
messages: Belongs to the HesB/IscA family.

13689:I6G65 RS08765
gene id: 13689:I6G65_RS08765
uniprot id: A0A411LK17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

13689:I6G65 RS05850
gene id: 13689:I6G65_RS05850
uniprot id: A0A411LIE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

13689:I6G65 RS02880
gene id: 13689:I6G65_RS02880
uniprot id: A0A411LGW0
names: Similarity
messages: Belongs to the TrpC family.

13689:I6G65 RS13510
gene id: 13689:I6G65_RS13510
uniprot id: A0A411LM96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

13689:I6G65 RS05245
gene id: 13689:I6G65_RS05245
uniprot id: A0A411LI66
names: Similarity
messages: Belongs to the pirin family.

13689:I6G65 RS18555
gene id: 13689:I6G65_RS18555
uniprot id: A0A411LFV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

13689:I6G65 RS07605
gene id: 13689:I6G65_RS07605
uniprot id: A0A411LJA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS19030
gene id: 13689:I6G65_RS19030
uniprot id: A0A7Y2KQ49
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

13689:I6G65 RS13190
gene id: 13689:I6G65_RS13190
uniprot id: A0A411LM06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS11450
gene id: 13689:I6G65_RS11450
uniprot id: A0A411LL91
names: Caution
names: Similarity
messages: Belongs to the MipA/OmpV family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS10505
gene id: 13689:I6G65_RS10505
uniprot id: A0A411LKS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

13689:I6G65 RS04305
gene id: 13689:I6G65_RS04305
uniprot id: A0A7Y2KRZ1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS15120
gene id: 13689:I6G65_RS15120
uniprot id: A0A411LN11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

13689:I6G65 RS11385
gene id: 13689:I6G65_RS11385
uniprot id: A0A411LLD1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

13689:I6G65 RS11910
gene id: 13689:I6G65_RS11910
uniprot id: A0A411LLI0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

13689:I6G65 RS16380
gene id: 13689:I6G65_RS16380
uniprot id: A0A411LEJ4
names: Similarity
messages: Belongs to the GcvT family.

13689:I6G65 RS06735
gene id: 13689:I6G65_RS06735
uniprot id: A0A411LIT9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

13689:I6G65 RS05045
gene id: 13689:I6G65_RS05045
uniprot id: A0A411LHX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

13689:I6G65 RS06290
gene id: 13689:I6G65_RS06290
uniprot id: A0A411LIP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

13689:I6G65 RS06065
gene id: 13689:I6G65_RS06065
uniprot id: A0A411LIJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

13689:I6G65 RS18120
gene id: 13689:I6G65_RS18120
uniprot id: A0A7Y2PCB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

13689:I6G65 RS18700
gene id: 13689:I6G65_RS18700
uniprot id: A0A411LFU4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS08845
gene id: 13689:I6G65_RS08845
uniprot id: A0A411LK18
names: Similarity
messages: Belongs to the type III secretion exporter family.

13689:I6G65 RS07420
gene id: 13689:I6G65_RS07420
uniprot id: A0A411LJ94
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

13689:I6G65 RS01435
gene id: 13689:I6G65_RS01435
uniprot id: A0A7T3AEA0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

13689:I6G65 RS07070
gene id: 13689:I6G65_RS07070
uniprot id: A0A411LJ53
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

13689:I6G65 RS00055
gene id: 13689:I6G65_RS00055
uniprot id: A0A031J9C6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

13689:I6G65 RS16485
gene id: 13689:I6G65_RS16485
uniprot id: A0A7T3E4A4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

13689:I6G65 RS02380
gene id: 13689:I6G65_RS02380
uniprot id: A0A411LNI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS16330
gene id: 13689:I6G65_RS16330
uniprot id: A0A411LEI1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

13689:I6G65 RS05345
gene id: 13689:I6G65_RS05345
uniprot id: A0A411LI86
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

13689:I6G65 RS06525
gene id: 13689:I6G65_RS06525
uniprot id: A0A411LIU5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

13689:I6G65 RS06715
gene id: 13689:I6G65_RS06715
uniprot id: A0A411LJ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

13689:I6G65 RS13905
gene id: 13689:I6G65_RS13905
uniprot id: A0A411LMG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

13689:I6G65 RS10855
gene id: 13689:I6G65_RS10855
uniprot id: A0A411LKZ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

13689:I6G65 RS16235
gene id: 13689:I6G65_RS16235
uniprot id: A0A411LEG1
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS18685
gene id: 13689:I6G65_RS18685
uniprot id: A0A411LFV0
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS16210
gene id: 13689:I6G65_RS16210
uniprot id: A0A411LEG2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS19515
gene id: 13689:I6G65_RS19515
uniprot id: A0A411LFD4
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

13689:I6G65 RS19165
gene id: 13689:I6G65_RS19165
uniprot id: A0A411LFM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

13689:I6G65 RS07095
gene id: 13689:I6G65_RS07095
uniprot id: A0A411LJ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

13689:I6G65 RS01615
gene id: 13689:I6G65_RS01615
uniprot id: A0A031J2R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

13689:I6G65 RS10215
gene id: 13689:I6G65_RS10215
uniprot id: A0A411LKL7
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS13735
gene id: 13689:I6G65_RS13735
uniprot id: A0A411LME6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

13689:I6G65 RS17145
gene id: 13689:I6G65_RS17145
uniprot id: A0A411LES7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

13689:I6G65 RS18415
gene id: 13689:I6G65_RS18415
uniprot id: A0A411LG06
names: Similarity
messages: Belongs to the DapA family.

13689:I6G65 RS06375
gene id: 13689:I6G65_RS06375
uniprot id: A0A411LIM5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

13689:I6G65 RS16435
gene id: 13689:I6G65_RS16435
uniprot id: A0A7Y2PC37
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

13689:I6G65 RS07385
gene id: 13689:I6G65_RS07385
uniprot id: A0A411LNX5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

13689:I6G65 RS17905
gene id: 13689:I6G65_RS17905
uniprot id: A0A411LEZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

13689:I6G65 RS10395
gene id: 13689:I6G65_RS10395
uniprot id: A0A411LKS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

13689:I6G65 RS14050
gene id: 13689:I6G65_RS14050
uniprot id: A0A7Y2PAY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

13689:I6G65 RS13675
gene id: 13689:I6G65_RS13675
uniprot id: A0A411LMG0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

13689:I6G65 RS17910
gene id: 13689:I6G65_RS17910
uniprot id: A0A411LEZ2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

13689:I6G65 RS15380
gene id: 13689:I6G65_RS15380
uniprot id: A0A411LN53
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

13689:I6G65 RS06400
gene id: 13689:I6G65_RS06400
uniprot id: A0A411LIV9
names: Similarity
messages: Belongs to the LOG family.

13689:I6G65 RS07120
gene id: 13689:I6G65_RS07120
uniprot id: A0A411LIZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS09290
gene id: 13689:I6G65_RS09290
uniprot id: A0A411LKB5
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS16225
gene id: 13689:I6G65_RS16225
uniprot id: A0A7T3A9C4
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS08280
gene id: 13689:I6G65_RS08280
uniprot id: A0A411LJR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

13689:I6G65 RS10780
gene id: 13689:I6G65_RS10780
uniprot id: A0A411LKX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

13689:I6G65 RS08060
gene id: 13689:I6G65_RS08060
uniprot id: A0A7Y2KSX9
names: Caution
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS09860
gene id: 13689:I6G65_RS09860
uniprot id: A0A411LKI2
names: Similarity
messages: Belongs to the OprB family.

13689:I6G65 RS08065
gene id: 13689:I6G65_RS08065
uniprot id: A0A411LJN1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

13689:I6G65 RS11070
gene id: 13689:I6G65_RS11070
uniprot id: A0A411LL81
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

13689:I6G65 RS13400
gene id: 13689:I6G65_RS13400
uniprot id: A0A411LM86
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

13689:I6G65 RS14235
gene id: 13689:I6G65_RS14235
uniprot id: A0A411LML0
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

13689:I6G65 RS05510
gene id: 13689:I6G65_RS05510
uniprot id: A0A411LI59
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

13689:I6G65 RS17535
gene id: 13689:I6G65_RS17535
uniprot id: A0A7Y2KLI3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS14380
gene id: 13689:I6G65_RS14380
uniprot id: A0A411LMR1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

13689:I6G65 RS09415
gene id: 13689:I6G65_RS09415
uniprot id: A0A411LKB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

13689:I6G65 RS09130
gene id: 13689:I6G65_RS09130
uniprot id: A0A411LK63
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

13689:I6G65 RS07355
gene id: 13689:I6G65_RS07355
uniprot id: A0A411LJ63
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

13689:I6G65 RS04985
gene id: 13689:I6G65_RS04985
uniprot id: A0A411LHY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

13689:I6G65 RS19510
gene id: 13689:I6G65_RS19510
uniprot id: A0A411LFK6
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

13689:I6G65 RS11975
gene id: 13689:I6G65_RS11975
uniprot id: A0A411LLG9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

13689:I6G65 RS18025
gene id: 13689:I6G65_RS18025
uniprot id: A0A411LF18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

13689:I6G65 RS18020
gene id: 13689:I6G65_RS18020
uniprot id: A0A411LF21
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

13689:I6G65 RS15640
gene id: 13689:I6G65_RS15640
uniprot id: A0A411LN87
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

13689:I6G65 RS14095
gene id: 13689:I6G65_RS14095
uniprot id: A0A411LMK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

13689:I6G65 RS10630
gene id: 13689:I6G65_RS10630
uniprot id: A0A411LL13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

13689:I6G65 RS17290
gene id: 13689:I6G65_RS17290
uniprot id: A0A411LEQ6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

13689:I6G65 RS11685
gene id: 13689:I6G65_RS11685
uniprot id: A0A7T3ADR9
names: Similarity
messages: Belongs to the AlaDH/PNT family.

13689:I6G65 RS13465
gene id: 13689:I6G65_RS13465
uniprot id: A0A411LM53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS17555
gene id: 13689:I6G65_RS17555
uniprot id: A0A411LEZ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

13689:I6G65 RS10045
gene id: 13689:I6G65_RS10045
uniprot id: A0A411LKL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

13689:I6G65 RS08575
gene id: 13689:I6G65_RS08575
uniprot id: A0A411LJW9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

13689:I6G65 RS18865
gene id: 13689:I6G65_RS18865
uniprot id: A0A411LFR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

13689:I6G65 RS11230
gene id: 13689:I6G65_RS11230
uniprot id: A0A411LL53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS08540
gene id: 13689:I6G65_RS08540
uniprot id: A0A411LP41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS02665
gene id: 13689:I6G65_RS02665
uniprot id: A0A411LGM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS01740
gene id: 13689:I6G65_RS01740
uniprot id: A0A7T3AE24
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

13689:I6G65 RS13850
gene id: 13689:I6G65_RS13850
uniprot id: A0A411LMF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

13689:I6G65 RS10560
gene id: 13689:I6G65_RS10560
uniprot id: A0A411LKT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

13689:I6G65 RS13670
gene id: 13689:I6G65_RS13670
uniprot id: A0A411LMC8
names: Similarity
messages: Belongs to the CobH/CbiC family.

13689:I6G65 RS09505
gene id: 13689:I6G65_RS09505
uniprot id: A0A411LKD1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

13689:I6G65 RS15200
gene id: 13689:I6G65_RS15200
uniprot id: A0A411LN32
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

13689:I6G65 RS19635
gene id: 13689:I6G65_RS19635
uniprot id: A0A411LFC1
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS11870
gene id: 13689:I6G65_RS11870
uniprot id: A0A411LLE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS06490
gene id: 13689:I6G65_RS06490
uniprot id: A0A411LIR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

13689:I6G65 RS12400
gene id: 13689:I6G65_RS12400
uniprot id: A0A411LLQ6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

13689:I6G65 RS05395
gene id: 13689:I6G65_RS05395
uniprot id: A0A411LI96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS13415
gene id: 13689:I6G65_RS13415
uniprot id: A0A411LM84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

13689:I6G65 RS03105
gene id: 13689:I6G65_RS03105
uniprot id: A0A411LH26
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

13689:I6G65 RS08760
gene id: 13689:I6G65_RS08760
uniprot id: A0A411LK06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

13689:I6G65 RS02895
gene id: 13689:I6G65_RS02895
uniprot id: A0A411LGW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

13689:I6G65 RS07265
gene id: 13689:I6G65_RS07265
uniprot id: A0A411LJ41
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS13225
gene id: 13689:I6G65_RS13225
uniprot id: A0A411LM88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

13689:I6G65 RS04535
gene id: 13689:I6G65_RS04535
uniprot id: A0A411LHM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

13689:I6G65 RS06030
gene id: 13689:I6G65_RS06030
uniprot id: A0A411LIJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

13689:I6G65 RS07530
gene id: 13689:I6G65_RS07530
uniprot id: A0A411LJB5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS18995
gene id: 13689:I6G65_RS18995
uniprot id: A0A411LFP6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS04850
gene id: 13689:I6G65_RS04850
uniprot id: Q93UV0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the condensation of L-serine with palmitoyl-CoA (hexadecanoyl-CoA) to produce 3-oxosphinganine (PubMed:11279212, PubMed:17557831, PubMed:17559874, PubMed:19376777). Exhibits a broad substrate specificity concerning the chain length and the degree of unsaturation of acyl-CoA (PubMed:11279212, PubMed:19376777).
messages: Cytoplasm
messages: Homodimer.
messages: Not inhibited by relatively high concentrations of palmitoyl-CoA (PubMed:11279212). Inhibited by both D-cycloserine (DCS) and L-cycloserine (LCS), which inactivate SPT by transamination to form a free pyridoxamine 5'-phosphate (PMP) and beta-aminooxyacetaldehyde that remain bound at the active site (PubMed:20445930). Inhibition is reversed by incubation with excess pyridoxal phosphate (PubMed:20445930). Inhibited by the fungal natural product myriocin, which acts as a competitive inhibitor for both L-serine and palmitoyl-CoA substrates (PubMed:23957439).

13689:I6G65 RS06585
gene id: 13689:I6G65_RS06585
uniprot id: A0A411LIQ5
names: Caution
names: Similarity
messages: In the N-terminal section; belongs to the cytochrome P450 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS17790
gene id: 13689:I6G65_RS17790
uniprot id: A0A411LEX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

13689:I6G65 RS13765
gene id: 13689:I6G65_RS13765
uniprot id: A0A411LMD6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS17835
gene id: 13689:I6G65_RS17835
uniprot id: A0A411LEZ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

13689:I6G65 RS09480
gene id: 13689:I6G65_RS09480
uniprot id: A0A411LP31
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

13689:I6G65 RS19505
gene id: 13689:I6G65_RS19505
uniprot id: A0A411LFE3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

13689:I6G65 RS13840
gene id: 13689:I6G65_RS13840
uniprot id: A0A411LPC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

13689:I6G65 RS11945
gene id: 13689:I6G65_RS11945
uniprot id: A0A411LLH1
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

13689:I6G65 RS10345
gene id: 13689:I6G65_RS10345
uniprot id: A0A411LKR5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS09600
gene id: 13689:I6G65_RS09600
uniprot id: A0A411LKF2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

13689:I6G65 RS13645
gene id: 13689:I6G65_RS13645
uniprot id: A0A411LMC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

13689:I6G65 RS00050
gene id: 13689:I6G65_RS00050
uniprot id: A0A031J7C1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

13689:I6G65 RS06060
gene id: 13689:I6G65_RS06060
uniprot id: A0A411LIL1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

13689:I6G65 RS15295
gene id: 13689:I6G65_RS15295
uniprot id: A0A411LPE6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

13689:I6G65 RS06050
gene id: 13689:I6G65_RS06050
uniprot id: A0A411LIQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

13689:I6G65 RS07020
gene id: 13689:I6G65_RS07020
uniprot id: A0A411LJ11
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

13689:I6G65 RS18260
gene id: 13689:I6G65_RS18260
uniprot id: A0A411LF62
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

13689:I6G65 RS03885
gene id: 13689:I6G65_RS03885
uniprot id: A0A411LH82
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

13689:I6G65 RS14215
gene id: 13689:I6G65_RS14215
uniprot id: A0A411LMM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

13689:I6G65 RS03835
gene id: 13689:I6G65_RS03835
uniprot id: A0A411LH75
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS06005
gene id: 13689:I6G65_RS06005
uniprot id: A0A411LIJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

13689:I6G65 RS14480
gene id: 13689:I6G65_RS14480
uniprot id: A0A411LMQ0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS05295
gene id: 13689:I6G65_RS05295
uniprot id: A0A411LI76
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

13689:I6G65 RS08955
gene id: 13689:I6G65_RS08955
uniprot id: A0A7Y2PDW3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

13689:I6G65 RS11620
gene id: 13689:I6G65_RS11620
uniprot id: A0A411LLC2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

13689:I6G65 RS07555
gene id: 13689:I6G65_RS07555
uniprot id: A0A411LNU0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS14720
gene id: 13689:I6G65_RS14720
uniprot id: A0A411LMP6
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

13689:I6G65 RS13490
gene id: 13689:I6G65_RS13490
uniprot id: A0A411LM85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

13689:I6G65 RS09930
gene id: 13689:I6G65_RS09930
uniprot id: A0A411LP52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

13689:I6G65 RS06495
gene id: 13689:I6G65_RS06495
uniprot id: A0A411LIP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

13689:I6G65 RS17815
gene id: 13689:I6G65_RS17815
uniprot id: A0A411LEX2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

13689:I6G65 RS06295
gene id: 13689:I6G65_RS06295
uniprot id: A0A411LIQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

13689:I6G65 RS14045
gene id: 13689:I6G65_RS14045
uniprot id: A0A411LMK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

13689:I6G65 RS13990
gene id: 13689:I6G65_RS13990
uniprot id: A0A411LMI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

13689:I6G65 RS12710
gene id: 13689:I6G65_RS12710
uniprot id: A0A411LLU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

13689:I6G65 RS11280
gene id: 13689:I6G65_RS11280
uniprot id: A0A411LP28
names: Similarity
messages: Belongs to the peptidase M1 family.

13689:I6G65 RS06345
gene id: 13689:I6G65_RS06345
uniprot id: A0A411LIL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

13689:I6G65 RS07795
gene id: 13689:I6G65_RS07795
uniprot id: A0A411LJI4
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

13689:I6G65 RS07110
gene id: 13689:I6G65_RS07110
uniprot id: A0A411LJ03
names: Similarity
messages: Belongs to the UPF0111 family.

13689:I6G65 RS16800
gene id: 13689:I6G65_RS16800
uniprot id: A0A7T3E3B5
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

13689:I6G65 RS08285
gene id: 13689:I6G65_RS08285
uniprot id: A0A411LP11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

13689:I6G65 RS08985
gene id: 13689:I6G65_RS08985
uniprot id: A0A411LK45
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

13689:I6G65 RS05600
gene id: 13689:I6G65_RS05600
uniprot id: A0A411LIB8
names: Similarity
messages: Belongs to the peptidase A24 family.

13689:I6G65 RS11430
gene id: 13689:I6G65_RS11430
uniprot id: A0A411LL75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

13689:I6G65 RS08530
gene id: 13689:I6G65_RS08530
uniprot id: A0A411LJX6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

13689:I6G65 RS01645
gene id: 13689:I6G65_RS01645
uniprot id: A0A7T3E7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS04785
gene id: 13689:I6G65_RS04785
uniprot id: A0A411LHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

13689:I6G65 RS06615
gene id: 13689:I6G65_RS06615
uniprot id: A0A411LIS0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-56 and Arg-59) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

13689:I6G65 RS16605
gene id: 13689:I6G65_RS16605
uniprot id: A0A7T3A8G4
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS02355
gene id: 13689:I6G65_RS02355
uniprot id: A0A411LNM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

13689:I6G65 RS03000
gene id: 13689:I6G65_RS03000
uniprot id: A0A411LGU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

13689:I6G65 RS06610
gene id: 13689:I6G65_RS06610
uniprot id: A0A411LIT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

13689:I6G65 RS06825
gene id: 13689:I6G65_RS06825
uniprot id: A0A411LIU6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS02965
gene id: 13689:I6G65_RS02965
uniprot id: A0A411LGZ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS03445
gene id: 13689:I6G65_RS03445
uniprot id: A0A411LH11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS11215
gene id: 13689:I6G65_RS11215
uniprot id: A0A7T3E6B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS08430
gene id: 13689:I6G65_RS08430
uniprot id: A0A411LJW4
names: Similarity
messages: Belongs to the peptidase M16 family.

13689:I6G65 RS07350
gene id: 13689:I6G65_RS07350
uniprot id: A0A411LJ81
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS02735
gene id: 13689:I6G65_RS02735
uniprot id: A0A411LGQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

13689:I6G65 RS12915
gene id: 13689:I6G65_RS12915
uniprot id: A0A411LLW0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

13689:I6G65 RS01475
gene id: 13689:I6G65_RS01475
uniprot id: A0A7T3E7U7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

13689:I6G65 RS02530
gene id: 13689:I6G65_RS02530
uniprot id: A0A411LNL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

13689:I6G65 RS03050
gene id: 13689:I6G65_RS03050
uniprot id: A0A411LGY9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

13689:I6G65 RS06160
gene id: 13689:I6G65_RS06160
uniprot id: A0A411LII2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

13689:I6G65 RS13630
gene id: 13689:I6G65_RS13630
uniprot id: A0A411LMB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

13689:I6G65 RS13035
gene id: 13689:I6G65_RS13035
uniprot id: A0A411LM13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

13689:I6G65 RS05185
gene id: 13689:I6G65_RS05185
uniprot id: A0A411LHZ8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

13689:I6G65 RS14775
gene id: 13689:I6G65_RS14775
uniprot id: A0A411LMQ6
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS10725
gene id: 13689:I6G65_RS10725
uniprot id: A0A411LKW5
names: Similarity
messages: Belongs to the aspartokinase family.

13689:I6G65 RS11780
gene id: 13689:I6G65_RS11780
uniprot id: A0A411LLE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

13689:I6G65 RS01225
gene id: 13689:I6G65_RS01225
uniprot id: A0A7T3AG85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

13689:I6G65 RS07430
gene id: 13689:I6G65_RS07430
uniprot id: A0A411LJ70
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

13689:I6G65 RS18335
gene id: 13689:I6G65_RS18335
uniprot id: A0A411LF67
names: Similarity
messages: Belongs to the histone deacetylase family.

13689:I6G65 RS01400
gene id: 13689:I6G65_RS01400
uniprot id: A0A7T3AG64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

13689:I6G65 RS11660
gene id: 13689:I6G65_RS11660
uniprot id: A0A411LLC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

13689:I6G65 RS18600
gene id: 13689:I6G65_RS18600
uniprot id: A0A411LG09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS00715
gene id: 13689:I6G65_RS00715
uniprot id: A0A7T3E858
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

13689:I6G65 RS07325
gene id: 13689:I6G65_RS07325
uniprot id: A0A411LJ55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

13689:I6G65 RS01735
gene id: 13689:I6G65_RS01735
uniprot id: A0A7T3AG31
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

13689:I6G65 RS04950
gene id: 13689:I6G65_RS04950
uniprot id: A0A411LHW9
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

13689:I6G65 RS05935
gene id: 13689:I6G65_RS05935
uniprot id: A0A7Y2PE00
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

13689:I6G65 RS17075
gene id: 13689:I6G65_RS17075
uniprot id: A0A411LEL3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS05070
gene id: 13689:I6G65_RS05070
uniprot id: A0A411LI92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS09550
gene id: 13689:I6G65_RS09550
uniprot id: A0A411LKD2
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS13220
gene id: 13689:I6G65_RS13220
uniprot id: A0A411LM50
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

13689:I6G65 RS19805
gene id: 13689:I6G65_RS19805
uniprot id: A0A411LF91
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

13689:I6G65 RS09450
gene id: 13689:I6G65_RS09450
uniprot id: A0A411LKB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

13689:I6G65 RS18955
gene id: 13689:I6G65_RS18955
uniprot id: A0A7T3AA79
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

13689:I6G65 RS08090
gene id: 13689:I6G65_RS08090
uniprot id: A0A411LJP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS05775
gene id: 13689:I6G65_RS05775
uniprot id: A0A411LIB2
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

13689:I6G65 RS15210
gene id: 13689:I6G65_RS15210
uniprot id: A0A7Y2KT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS16240
gene id: 13689:I6G65_RS16240
uniprot id: A0A411LEG5
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

13689:I6G65 RS06955
gene id: 13689:I6G65_RS06955
uniprot id: A0A411LIW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

13689:I6G65 RS08170
gene id: 13689:I6G65_RS08170
uniprot id: A0A411LP01
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

13689:I6G65 RS08775
gene id: 13689:I6G65_RS08775
uniprot id: A0A411LK02
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

13689:I6G65 RS03465
gene id: 13689:I6G65_RS03465
uniprot id: A0A411LH74
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

13689:I6G65 RS03255
gene id: 13689:I6G65_RS03255
uniprot id: A0A411LH19
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

13689:I6G65 RS09135
gene id: 13689:I6G65_RS09135
uniprot id: A0A411LK71
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

13689:I6G65 RS19550
gene id: 13689:I6G65_RS19550
uniprot id: A0A7Y2KPZ5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

13689:I6G65 RS09940
gene id: 13689:I6G65_RS09940
uniprot id: A0A411LKJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS03840
gene id: 13689:I6G65_RS03840
uniprot id: A0A411LHA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

13689:I6G65 RS19830
gene id: 13689:I6G65_RS19830
uniprot id: A0A7T3AAI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

13689:I6G65 RS15445
gene id: 13689:I6G65_RS15445
uniprot id: A0A411LN62
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

13689:I6G65 RS13745
gene id: 13689:I6G65_RS13745
uniprot id: A0A411LMA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

13689:I6G65 RS18215
gene id: 13689:I6G65_RS18215
uniprot id: A0A411LF35
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

13689:I6G65 RS02825
gene id: 13689:I6G65_RS02825
uniprot id: A0A411LNQ3
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

13689:I6G65 RS10610
gene id: 13689:I6G65_RS10610
uniprot id: A0A411LKU5
names: Similarity
messages: Belongs to the threonine synthase family.

13689:I6G65 RS16700
gene id: 13689:I6G65_RS16700
uniprot id: A0A7T3A7P9
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS06755
gene id: 13689:I6G65_RS06755
uniprot id: A0A411LIU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

13689:I6G65 RS05515
gene id: 13689:I6G65_RS05515
uniprot id: A0A411LIG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

13689:I6G65 RS03950
gene id: 13689:I6G65_RS03950
uniprot id: A0A411LHA3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

13689:I6G65 RS04110
gene id: 13689:I6G65_RS04110
uniprot id: A0A411LHI2
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

13689:I6G65 RS18240
gene id: 13689:I6G65_RS18240
uniprot id: A0A411LF51
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

13689:I6G65 RS02435
gene id: 13689:I6G65_RS02435
uniprot id: A0A411LGI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

13689:I6G65 RS04810
gene id: 13689:I6G65_RS04810
uniprot id: A0A411LHU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

13689:I6G65 RS08440
gene id: 13689:I6G65_RS08440
uniprot id: A0A7Y2KT17
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS03790
gene id: 13689:I6G65_RS03790
uniprot id: A0A411LHA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

13689:I6G65 RS03250
gene id: 13689:I6G65_RS03250
uniprot id: A0A411LH16
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

13689:I6G65 RS17305
gene id: 13689:I6G65_RS17305
uniprot id: A0A411LER3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

13689:I6G65 RS10625
gene id: 13689:I6G65_RS10625
uniprot id: A0A411LKW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

13689:I6G65 RS12375
gene id: 13689:I6G65_RS12375
uniprot id: A0A411LLP6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

13689:I6G65 RS00090
gene id: 13689:I6G65_RS00090
uniprot id: A0A7Y2KN17
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

13689:I6G65 RS04865
gene id: 13689:I6G65_RS04865
uniprot id: A0A411LHZ7
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS17805
gene id: 13689:I6G65_RS17805
uniprot id: A0A411LEX0
names: Similarity
messages: Belongs to the MreC family.

13689:I6G65 RS08270
gene id: 13689:I6G65_RS08270
uniprot id: A0A411LJS6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

13689:I6G65 RS10430
gene id: 13689:I6G65_RS10430
uniprot id: A0A411LKR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

13689:I6G65 RS20650
gene id: 13689:I6G65_RS20650
uniprot id: A0A411LFM4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

13689:I6G65 RS09560
gene id: 13689:I6G65_RS09560
uniprot id: A0A411LP37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

13689:I6G65 RS10410
gene id: 13689:I6G65_RS10410
uniprot id: A0A411LKR0
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

13689:I6G65 RS19645
gene id: 13689:I6G65_RS19645
uniprot id: A0A411LFB4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS01185
gene id: 13689:I6G65_RS01185
uniprot id: A0A031J175
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

13689:I6G65 RS04425
gene id: 13689:I6G65_RS04425
uniprot id: A0A411LHL6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

13689:I6G65 RS10010
gene id: 13689:I6G65_RS10010
uniprot id: A0A411LKK8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

13689:I6G65 RS04465
gene id: 13689:I6G65_RS04465
uniprot id: A0A411LHI3
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

13689:I6G65 RS14510
gene id: 13689:I6G65_RS14510
uniprot id: A0A411LMS4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

13689:I6G65 RS05795
gene id: 13689:I6G65_RS05795
uniprot id: A0A411LIE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

13689:I6G65 RS04370
gene id: 13689:I6G65_RS04370
uniprot id: A0A411LHK6
names: Cofactor
names: Function
messages: Alkaline phosphatase with broad substrate specificity.
messages: Binds 2 Zn(2+) ions.

13689:I6G65 RS15540
gene id: 13689:I6G65_RS15540
uniprot id: A0A411LN65
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

13689:I6G65 RS13705
gene id: 13689:I6G65_RS13705
uniprot id: A0A411LME2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

13689:I6G65 RS09425
gene id: 13689:I6G65_RS09425
uniprot id: A0A411LKB0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

13689:I6G65 RS08710
gene id: 13689:I6G65_RS08710
uniprot id: A0A411LK07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. In Gram-negative bacteria, at least four rings, L, P, S and M are present, whereas Gram-positive bacteria lack the L and P rings. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF build up the proximal portion of the rod with about 6 subunits each. Rod assembly occurs by export via the flagellum-specific pathway of its constituent proteins and by their incorporation into the rod structure in the probable order of FlgB, FlgC, FlgF and FlgG. Another protein, FliE, also assembles onto the stable rod structure.

13689:I6G65 RS19375
gene id: 13689:I6G65_RS19375
uniprot id: A0A411LFI7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

13689:I6G65 RS06230
gene id: 13689:I6G65_RS06230
uniprot id: A0A411LIP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS08810
gene id: 13689:I6G65_RS08810
uniprot id: A0A411LK14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

13689:I6G65 RS18835
gene id: 13689:I6G65_RS18835
uniprot id: A0A411LFX2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

13689:I6G65 RS06900
gene id: 13689:I6G65_RS06900
uniprot id: A0A411LIV7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

13689:I6G65 RS14645
gene id: 13689:I6G65_RS14645
uniprot id: A0A411LMX4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS13755
gene id: 13689:I6G65_RS13755
uniprot id: A0A411LME5
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

13689:I6G65 RS15485
gene id: 13689:I6G65_RS15485
uniprot id: A0A411LNA5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS19750
gene id: 13689:I6G65_RS19750
uniprot id: A0A411LFB6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS07920
gene id: 13689:I6G65_RS07920
uniprot id: A0A7T3ACJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

13689:I6G65 RS06210
gene id: 13689:I6G65_RS06210
uniprot id: A0A411LIQ0
names: Similarity
messages: Belongs to the peptidase M16 family.

13689:I6G65 RS03770
gene id: 13689:I6G65_RS03770
uniprot id: A0A411LH64
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

13689:I6G65 RS01290
gene id: 13689:I6G65_RS01290
uniprot id: A0A7T3AEA2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

13689:I6G65 RS13230
gene id: 13689:I6G65_RS13230
uniprot id: A0A411LM58
names: Similarity
messages: Belongs to the PhoH family.

13689:I6G65 RS01170
gene id: 13689:I6G65_RS01170
uniprot id: A0A7T3AE55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

13689:I6G65 RS11980
gene id: 13689:I6G65_RS11980
uniprot id: A0A411LLH5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

13689:I6G65 RS07090
gene id: 13689:I6G65_RS07090
uniprot id: A0A411LJ20
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

13689:I6G65 RS05760
gene id: 13689:I6G65_RS05760
uniprot id: A0A411LIE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

13689:I6G65 RS05470
gene id: 13689:I6G65_RS05470
uniprot id: A0A411LIA0
names: Similarity
messages: Belongs to the peptidase C56 family.

13689:I6G65 RS13535
gene id: 13689:I6G65_RS13535
uniprot id: A0A411LMB3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

13689:I6G65 RS08055
gene id: 13689:I6G65_RS08055
uniprot id: A0A411LJM8
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

13689:I6G65 RS09055
gene id: 13689:I6G65_RS09055
uniprot id: A0A411LK65
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS08850
gene id: 13689:I6G65_RS08850
uniprot id: A0A411LK24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

13689:I6G65 RS13175
gene id: 13689:I6G65_RS13175
uniprot id: A0A411LM78
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS11515
gene id: 13689:I6G65_RS11515
uniprot id: A0A7Y2PB34
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

13689:I6G65 RS15725
gene id: 13689:I6G65_RS15725
uniprot id: A0A411LEI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

13689:I6G65 RS01780
gene id: 13689:I6G65_RS01780
uniprot id: A0A031J2T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS10455
gene id: 13689:I6G65_RS10455
uniprot id: A0A7T3E6L0
names: Subcellular Location Annotation
messages: Cytoplasm

13689:I6G65 RS11175
gene id: 13689:I6G65_RS11175
uniprot id: A0A7Y2KLK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS08625
gene id: 13689:I6G65_RS08625
uniprot id: A0A411LJX5
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

13689:I6G65 RS17215
gene id: 13689:I6G65_RS17215
uniprot id: A0A411LEQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

13689:I6G65 RS06110
gene id: 13689:I6G65_RS06110
uniprot id: A0A411LNS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

13689:I6G65 RS15405
gene id: 13689:I6G65_RS15405
uniprot id: A0A7Y2KTA2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

13689:I6G65 RS11985
gene id: 13689:I6G65_RS11985
uniprot id: A0A7T3ABW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

13689:I6G65 RS14690
gene id: 13689:I6G65_RS14690
uniprot id: A0A411LMS9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

13689:I6G65 RS01180
gene id: 13689:I6G65_RS01180
uniprot id: A0A7T3AFP3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

13689:I6G65 RS15205
gene id: 13689:I6G65_RS15205
uniprot id: A0A7Y2KT68
names: Caution
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS05720
gene id: 13689:I6G65_RS05720
uniprot id: A0A411LIA1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

13689:I6G65 RS16445
gene id: 13689:I6G65_RS16445
uniprot id: A0A411LEK3
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

13689:I6G65 RS18800
gene id: 13689:I6G65_RS18800
uniprot id: A0A411LFS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS15100
gene id: 13689:I6G65_RS15100
uniprot id: A0A411LN17
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

13689:I6G65 RS09625
gene id: 13689:I6G65_RS09625
uniprot id: A0A411LKE6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

13689:I6G65 RS15190
gene id: 13689:I6G65_RS15190
uniprot id: A0A411LN60
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS19740
gene id: 13689:I6G65_RS19740
uniprot id: A0A411LFB2
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS03070
gene id: 13689:I6G65_RS03070
uniprot id: A0A411LGZ9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS19395
gene id: 13689:I6G65_RS19395
uniprot id: A0A411LFG4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS17230
gene id: 13689:I6G65_RS17230
uniprot id: A0A411LEQ0
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

13689:I6G65 RS06190
gene id: 13689:I6G65_RS06190
uniprot id: A0A411LIK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

13689:I6G65 RS02790
gene id: 13689:I6G65_RS02790
uniprot id: A0A411LGW3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

13689:I6G65 RS18690
gene id: 13689:I6G65_RS18690
uniprot id: A0A411LNG2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

13689:I6G65 RS18525
gene id: 13689:I6G65_RS18525
uniprot id: A0A411LFY5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

13689:I6G65 RS11520
gene id: 13689:I6G65_RS11520
uniprot id: A0A411LL95
names: Similarity
messages: Belongs to the lycopene cyclase family.

13689:I6G65 RS00990
gene id: 13689:I6G65_RS00990
uniprot id: A0A7T3AEE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS03020
gene id: 13689:I6G65_RS03020
uniprot id: A0A411LH03
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

13689:I6G65 RS01955
gene id: 13689:I6G65_RS01955
uniprot id: A0A411LG41
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS14595
gene id: 13689:I6G65_RS14595
uniprot id: A0A411LMM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS02755
gene id: 13689:I6G65_RS02755
uniprot id: A0A411LGU2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

13689:I6G65 RS04520
gene id: 13689:I6G65_RS04520
uniprot id: A0A411LHV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

13689:I6G65 RS05815
gene id: 13689:I6G65_RS05815
uniprot id: A0A411LIC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS01990
gene id: 13689:I6G65_RS01990
uniprot id: A0A411LG79
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

13689:I6G65 RS07415
gene id: 13689:I6G65_RS07415
uniprot id: A0A411LJ56
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

13689:I6G65 RS08010
gene id: 13689:I6G65_RS08010
uniprot id: A0A411LJN8
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS10515
gene id: 13689:I6G65_RS10515
uniprot id: A0A411LKU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

13689:I6G65 RS02330
gene id: 13689:I6G65_RS02330
uniprot id: A0A411LGG9
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS01870
gene id: 13689:I6G65_RS01870
uniprot id: A0A411LG61
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

13689:I6G65 RS03985
gene id: 13689:I6G65_RS03985
uniprot id: A0A7Y2KQ11
names: Similarity
messages: Belongs to the manganese catalase family.

13689:I6G65 RS12395
gene id: 13689:I6G65_RS12395
uniprot id: A0A411LLP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS15545
gene id: 13689:I6G65_RS15545
uniprot id: A0A411LN74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

13689:I6G65 RS12785
gene id: 13689:I6G65_RS12785
uniprot id: A0A411LLV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

13689:I6G65 RS02405
gene id: 13689:I6G65_RS02405
uniprot id: A0A411LGE2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

13689:I6G65 RS14530
gene id: 13689:I6G65_RS14530
uniprot id: A0A411LML3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

13689:I6G65 RS08660
gene id: 13689:I6G65_RS08660
uniprot id: A0A411LJY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

13689:I6G65 RS01410
gene id: 13689:I6G65_RS01410
uniprot id: A0A7T3AEB2
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

13689:I6G65 RS17840
gene id: 13689:I6G65_RS17840
uniprot id: A0A411LEY7
names: Similarity
messages: Belongs to the fabD family.

13689:I6G65 RS18155
gene id: 13689:I6G65_RS18155
uniprot id: A0A411LF25
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

13689:I6G65 RS19465
gene id: 13689:I6G65_RS19465
uniprot id: A0A411LFE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

13689:I6G65 RS03900
gene id: 13689:I6G65_RS03900
uniprot id: A0A411LHA1
names: Similarity
messages: Belongs to the asparagine synthetase family.

13689:I6G65 RS14230
gene id: 13689:I6G65_RS14230
uniprot id: A0A411LML1
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS03480
gene id: 13689:I6G65_RS03480
uniprot id: A0A411LNQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

13689:I6G65 RS14985
gene id: 13689:I6G65_RS14985
uniprot id: A0A411LPD6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS07460
gene id: 13689:I6G65_RS07460
uniprot id: A0A411LJ76
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

13689:I6G65 RS01075
gene id: 13689:I6G65_RS01075
uniprot id: A0A7T3AEE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS18500
gene id: 13689:I6G65_RS18500
uniprot id: A0A411LFW8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

13689:I6G65 RS15575
gene id: 13689:I6G65_RS15575
uniprot id: A0A411LE57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

13689:I6G65 RS10655
gene id: 13689:I6G65_RS10655
uniprot id: A0A411LKV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

13689:I6G65 RS10400
gene id: 13689:I6G65_RS10400
uniprot id: A0A411LKX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

13689:I6G65 RS16895
gene id: 13689:I6G65_RS16895
uniprot id: A0A7Y2PF26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

13689:I6G65 RS19360
gene id: 13689:I6G65_RS19360
uniprot id: A0A411LFH9
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

13689:I6G65 RS12460
gene id: 13689:I6G65_RS12460
uniprot id: A0A411LLQ5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

13689:I6G65 RS14310
gene id: 13689:I6G65_RS14310
uniprot id: A0A7Y2KMQ4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

13689:I6G65 RS06960
gene id: 13689:I6G65_RS06960
uniprot id: A0A411LJ30
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS09850
gene id: 13689:I6G65_RS09850
uniprot id: A0A411LKI9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS17260
gene id: 13689:I6G65_RS17260
uniprot id: A0A411LEQ7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

13689:I6G65 RS18810
gene id: 13689:I6G65_RS18810
uniprot id: A0A411LFS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

13689:I6G65 RS13000
gene id: 13689:I6G65_RS13000
uniprot id: A0A411LLZ7
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

13689:I6G65 RS01840
gene id: 13689:I6G65_RS01840
uniprot id: A0A411LG13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS14495
gene id: 13689:I6G65_RS14495
uniprot id: A0A411LMS0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

13689:I6G65 RS19075
gene id: 13689:I6G65_RS19075
uniprot id: A0A411LFM8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

13689:I6G65 RS01580
gene id: 13689:I6G65_RS01580
uniprot id: A0A031J175
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

13689:I6G65 RS12750
gene id: 13689:I6G65_RS12750
uniprot id: A0A411LLX5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

13689:I6G65 RS05380
gene id: 13689:I6G65_RS05380
uniprot id: A0A411LI33
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

13689:I6G65 RS02555
gene id: 13689:I6G65_RS02555
uniprot id: A0A411LGR4
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS04805
gene id: 13689:I6G65_RS04805
uniprot id: A0A411LHW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

13689:I6G65 RS13600
gene id: 13689:I6G65_RS13600
uniprot id: A0A411LMC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

13689:I6G65 RS13370
gene id: 13689:I6G65_RS13370
uniprot id: A0A411LM81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

13689:I6G65 RS01015
gene id: 13689:I6G65_RS01015
uniprot id: A0A7T3AEJ1
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS16175
gene id: 13689:I6G65_RS16175
uniprot id: A0A411LEL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS20300
gene id: 13689:I6G65_RS20300
uniprot id: A0A7Y2KS37
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS12875
gene id: 13689:I6G65_RS12875
uniprot id: A0A411LLY3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

13689:I6G65 RS00005
gene id: 13689:I6G65_RS00005
uniprot id: A0A7T3AG23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

13689:I6G65 RS03045
gene id: 13689:I6G65_RS03045
uniprot id: A0A411LH15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

13689:I6G65 RS16500
gene id: 13689:I6G65_RS16500
uniprot id: A0A7T3ADP2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

13689:I6G65 RS15680
gene id: 13689:I6G65_RS15680
uniprot id: A0A411LEC9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

13689:I6G65 RS17855
gene id: 13689:I6G65_RS17855
uniprot id: A0A411LEY0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

13689:I6G65 RS14035
gene id: 13689:I6G65_RS14035
uniprot id: A0A411LMJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

13689:I6G65 RS05050
gene id: 13689:I6G65_RS05050
uniprot id: A0A411LI12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

13689:I6G65 RS18340
gene id: 13689:I6G65_RS18340
uniprot id: A0A411LF72
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

13689:I6G65 RS07980
gene id: 13689:I6G65_RS07980
uniprot id: A0A7T3AAD4
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

13689:I6G65 RS10390
gene id: 13689:I6G65_RS10390
uniprot id: A0A411LKR2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS06605
gene id: 13689:I6G65_RS06605
uniprot id: A0A411LIU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

13689:I6G65 RS14265
gene id: 13689:I6G65_RS14265
uniprot id: A0A411LMN3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

13689:I6G65 RS05610
gene id: 13689:I6G65_RS05610
uniprot id: A0A411LID9
names: Caution
names: Similarity
messages: Belongs to the bacterial secretin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS02855
gene id: 13689:I6G65_RS02855
uniprot id: A0A411LGX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS05475
gene id: 13689:I6G65_RS05475
uniprot id: A0A411LIA5
names: Similarity
messages: Belongs to the type IB topoisomerase family.

13689:I6G65 RS07410
gene id: 13689:I6G65_RS07410
uniprot id: A0A411LJA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

13689:I6G65 RS19005
gene id: 13689:I6G65_RS19005
uniprot id: A0A411LFU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

13689:I6G65 RS05305
gene id: 13689:I6G65_RS05305
uniprot id: A0A411LIC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS11375
gene id: 13689:I6G65_RS11375
uniprot id: A0A7Y2PBZ2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

13689:I6G65 RS08435
gene id: 13689:I6G65_RS08435
uniprot id: A0A411LJU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

13689:I6G65 RS12140
gene id: 13689:I6G65_RS12140
uniprot id: A0A7Y2KRL5
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS09375
gene id: 13689:I6G65_RS09375
uniprot id: A0A411LKB6
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

13689:I6G65 RS04585
gene id: 13689:I6G65_RS04585
uniprot id: A0A411LHW7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

13689:I6G65 RS06935
gene id: 13689:I6G65_RS06935
uniprot id: A0A411LIX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

13689:I6G65 RS16805
gene id: 13689:I6G65_RS16805
uniprot id: A0A7T3E3W7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

13689:I6G65 RS10005
gene id: 13689:I6G65_RS10005
uniprot id: A0A411LKK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

13689:I6G65 RS06420
gene id: 13689:I6G65_RS06420
uniprot id: A0A411LIN7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

13689:I6G65 RS19410
gene id: 13689:I6G65_RS19410
uniprot id: A0A411LFG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

13689:I6G65 RS18615
gene id: 13689:I6G65_RS18615
uniprot id: A0A411LFV1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

13689:I6G65 RS12090
gene id: 13689:I6G65_RS12090
uniprot id: A0A411LLJ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

13689:I6G65 RS12810
gene id: 13689:I6G65_RS12810
uniprot id: A0A411LLX3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS16345
gene id: 13689:I6G65_RS16345
uniprot id: A0A411LEI4
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS09950
gene id: 13689:I6G65_RS09950
uniprot id: A0A411LKJ3
names: Similarity
messages: Belongs to the UPF0235 family.

13689:I6G65 RS15320
gene id: 13689:I6G65_RS15320
uniprot id: A0A7T3A6P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

13689:I6G65 RS16155
gene id: 13689:I6G65_RS16155
uniprot id: A0A411LEF3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

13689:I6G65 RS13925
gene id: 13689:I6G65_RS13925
uniprot id: A0A411LMC9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

13689:I6G65 RS05195
gene id: 13689:I6G65_RS05195
uniprot id: A0A411LI50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

13689:I6G65 RS08835
gene id: 13689:I6G65_RS08835
uniprot id: A0A411LK13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

13689:I6G65 RS14375
gene id: 13689:I6G65_RS14375
uniprot id: A0A411LMT3
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

13689:I6G65 RS01065
gene id: 13689:I6G65_RS01065
uniprot id: A0A7T3AGA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS06115
gene id: 13689:I6G65_RS06115
uniprot id: A0A411LIM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

13689:I6G65 RS16890
gene id: 13689:I6G65_RS16890
uniprot id: A0A7Y2KRB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS05975
gene id: 13689:I6G65_RS05975
uniprot id: A0A411LNX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

13689:I6G65 RS02975
gene id: 13689:I6G65_RS02975
uniprot id: A0A411LGX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

13689:I6G65 RS05575
gene id: 13689:I6G65_RS05575
uniprot id: A0A7T3A9T3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

13689:I6G65 RS04835
gene id: 13689:I6G65_RS04835
uniprot id: A0A411LHZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

13689:I6G65 RS16975
gene id: 13689:I6G65_RS16975
uniprot id: A0A7Y2PF19
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS14670
gene id: 13689:I6G65_RS14670
uniprot id: A0A411LMU2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

13689:I6G65 RS05030
gene id: 13689:I6G65_RS05030
uniprot id: A0A411LI01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

13689:I6G65 RS12305
gene id: 13689:I6G65_RS12305
uniprot id: A0A411LLM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

13689:I6G65 RS05700
gene id: 13689:I6G65_RS05700
uniprot id: A0A411LID8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

13689:I6G65 RS06760
gene id: 13689:I6G65_RS06760
uniprot id: A0A7Y2PC23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

13689:I6G65 RS01545
gene id: 13689:I6G65_RS01545
uniprot id: A0A7T3E781
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS02645
gene id: 13689:I6G65_RS02645
uniprot id: A0A411LGR9
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS07025
gene id: 13689:I6G65_RS07025
uniprot id: A0A411LJ17
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

13689:I6G65 RS06020
gene id: 13689:I6G65_RS06020
uniprot id: A0A411LIG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

13689:I6G65 RS15730
gene id: 13689:I6G65_RS15730
uniprot id: A0A411LED7
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

13689:I6G65 RS12940
gene id: 13689:I6G65_RS12940
uniprot id: A0A411LLY8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

13689:I6G65 RS05825
gene id: 13689:I6G65_RS05825
uniprot id: A0A411LIC2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

13689:I6G65 RS15450
gene id: 13689:I6G65_RS15450
uniprot id: A0A411LN94
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

13689:I6G65 RS13980
gene id: 13689:I6G65_RS13980
uniprot id: A0A411LMH5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

13689:I6G65 RS08675
gene id: 13689:I6G65_RS08675
uniprot id: A0A411LJY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

13689:I6G65 RS05865
gene id: 13689:I6G65_RS05865
uniprot id: A0A411LID7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

13689:I6G65 RS06745
gene id: 13689:I6G65_RS06745
uniprot id: A0A411LIW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

13689:I6G65 RS17330
gene id: 13689:I6G65_RS17330
uniprot id: A0A411LER0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

13689:I6G65 RS16260
gene id: 13689:I6G65_RS16260
uniprot id: A0A411LEH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS15720
gene id: 13689:I6G65_RS15720
uniprot id: A0A7T3A796
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS13445
gene id: 13689:I6G65_RS13445
uniprot id: A0A411LM89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

13689:I6G65 RS12525
gene id: 13689:I6G65_RS12525
uniprot id: A0A411LLX6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

13689:I6G65 RS16200
gene id: 13689:I6G65_RS16200
uniprot id: A0A411LEG7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

13689:I6G65 RS18760
gene id: 13689:I6G65_RS18760
uniprot id: A0A411LFT3
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

13689:I6G65 RS18925
gene id: 13689:I6G65_RS18925
uniprot id: A0A411LFQ8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

13689:I6G65 RS04830
gene id: 13689:I6G65_RS04830
uniprot id: A0A7T3E6M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

13689:I6G65 RS13595
gene id: 13689:I6G65_RS13595
uniprot id: A0A411LMB0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

13689:I6G65 RS03215
gene id: 13689:I6G65_RS03215
uniprot id: A0A411LH20
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

13689:I6G65 RS07060
gene id: 13689:I6G65_RS07060
uniprot id: A0A411LJ45
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

13689:I6G65 RS17860
gene id: 13689:I6G65_RS17860
uniprot id: A0A411LEY6
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

13689:I6G65 RS09660
gene id: 13689:I6G65_RS09660
uniprot id: A0A7Y2KL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

13689:I6G65 RS08265
gene id: 13689:I6G65_RS08265
uniprot id: A0A411LJR2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

13689:I6G65 RS02800
gene id: 13689:I6G65_RS02800
uniprot id: A0A411LGU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS16360
gene id: 13689:I6G65_RS16360
uniprot id: A0A411LEI2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

13689:I6G65 RS00080
gene id: 13689:I6G65_RS00080
uniprot id: A0A7Y2KP42
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

13689:I6G65 RS18610
gene id: 13689:I6G65_RS18610
uniprot id: A0A7Y2KQA2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS00075
gene id: 13689:I6G65_RS00075
uniprot id: A0A7Y2KMX9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS05310
gene id: 13689:I6G65_RS05310
uniprot id: A0A411LI71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

13689:I6G65 RS17155
gene id: 13689:I6G65_RS17155
uniprot id: A0A411LEN2
names: Similarity
messages: Belongs to the ArsC family.

13689:I6G65 RS17680
gene id: 13689:I6G65_RS17680
uniprot id: A0A411LEV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

13689:I6G65 RS16370
gene id: 13689:I6G65_RS16370
uniprot id: A0A411LEN8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

13689:I6G65 RS08970
gene id: 13689:I6G65_RS08970
uniprot id: A0A411LK41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

13689:I6G65 RS06170
gene id: 13689:I6G65_RS06170
uniprot id: A0A411LIN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

13689:I6G65 RS03640
gene id: 13689:I6G65_RS03640
uniprot id: A0A411LH57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

13689:I6G65 RS16575
gene id: 13689:I6G65_RS16575
uniprot id: A0A7T3A7G7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

13689:I6G65 RS06010
gene id: 13689:I6G65_RS06010
uniprot id: A0A411LIK2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

13689:I6G65 RS14125
gene id: 13689:I6G65_RS14125
uniprot id: A0A411LMJ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

13689:I6G65 RS18680
gene id: 13689:I6G65_RS18680
uniprot id: A0A411LFV8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS06175
gene id: 13689:I6G65_RS06175
uniprot id: A0A411LNW5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

13689:I6G65 RS09610
gene id: 13689:I6G65_RS09610
uniprot id: A0A411LKE5
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS08920
gene id: 13689:I6G65_RS08920
uniprot id: A0A411LK52
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

13689:I6G65 RS11335
gene id: 13689:I6G65_RS11335
uniprot id: A0A411LL72
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

13689:I6G65 RS09420
gene id: 13689:I6G65_RS09420
uniprot id: A0A411LKD4
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS02535
gene id: 13689:I6G65_RS02535
uniprot id: A0A411LGK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS08680
gene id: 13689:I6G65_RS08680
uniprot id: A0A7T3E7I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

13689:I6G65 RS12285
gene id: 13689:I6G65_RS12285
uniprot id: A0A411LLN1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

13689:I6G65 RS03995
gene id: 13689:I6G65_RS03995
uniprot id: A0A411LHD5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

13689:I6G65 RS19025
gene id: 13689:I6G65_RS19025
uniprot id: A0A411LFN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

13689:I6G65 RS16820
gene id: 13689:I6G65_RS16820
uniprot id: A0A7T3A771
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

13689:I6G65 RS08550
gene id: 13689:I6G65_RS08550
uniprot id: A0A411LJW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

13689:I6G65 RS14210
gene id: 13689:I6G65_RS14210
uniprot id: A0A411LMH6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

13689:I6G65 RS19385
gene id: 13689:I6G65_RS19385
uniprot id: A0A411LFI1
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

13689:I6G65 RS13860
gene id: 13689:I6G65_RS13860
uniprot id: A0A411LMG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

13689:I6G65 RS15115
gene id: 13689:I6G65_RS15115
uniprot id: A0A411LN02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS10230
gene id: 13689:I6G65_RS10230
uniprot id: A0A411LKM6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

13689:I6G65 RS17255
gene id: 13689:I6G65_RS17255
uniprot id: A0A411LEQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

13689:I6G65 RS12895
gene id: 13689:I6G65_RS12895
uniprot id: A0A411LLY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

13689:I6G65 RS15000
gene id: 13689:I6G65_RS15000
uniprot id: A0A411LMY0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS17200
gene id: 13689:I6G65_RS17200
uniprot id: A0A411LEP7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

13689:I6G65 RS08840
gene id: 13689:I6G65_RS08840
uniprot id: A0A411LK20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

13689:I6G65 RS13020
gene id: 13689:I6G65_RS13020
uniprot id: A0A411LM00
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

13689:I6G65 RS13910
gene id: 13689:I6G65_RS13910
uniprot id: A0A411LMJ5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

13689:I6G65 RS08730
gene id: 13689:I6G65_RS08730
uniprot id: A0A411LK01
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

13689:I6G65 RS07765
gene id: 13689:I6G65_RS07765
uniprot id: A0A411LJD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS09385
gene id: 13689:I6G65_RS09385
uniprot id: A0A411LKB2
names: Similarity
messages: Belongs to the peptidase U62 family.

13689:I6G65 RS17700
gene id: 13689:I6G65_RS17700
uniprot id: A0A411LEW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

13689:I6G65 RS19080
gene id: 13689:I6G65_RS19080
uniprot id: A0A411LFP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS17055
gene id: 13689:I6G65_RS17055
uniprot id: A0A411LEL7
names: Similarity
messages: Belongs to the RecJ family.

13689:I6G65 RS08150
gene id: 13689:I6G65_RS08150
uniprot id: A0A411LJP5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

13689:I6G65 RS15520
gene id: 13689:I6G65_RS15520
uniprot id: A0A411LN27
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

13689:I6G65 RS06380
gene id: 13689:I6G65_RS06380
uniprot id: A0A411LIR0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

13689:I6G65 RS02420
gene id: 13689:I6G65_RS02420
uniprot id: A0A411LGI6
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

13689:I6G65 RS17950
gene id: 13689:I6G65_RS17950
uniprot id: A0A411LF15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS13915
gene id: 13689:I6G65_RS13915
uniprot id: A0A411LMH7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

13689:I6G65 RS07995
gene id: 13689:I6G65_RS07995
uniprot id: A0A411LJL6
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

13689:I6G65 RS18570
gene id: 13689:I6G65_RS18570
uniprot id: A0A411LFY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

13689:I6G65 RS18040
gene id: 13689:I6G65_RS18040
uniprot id: A0A7Y2PDZ7
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS14825
gene id: 13689:I6G65_RS14825
uniprot id: A0A7Y2PDG4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS03560
gene id: 13689:I6G65_RS03560
uniprot id: A0A411LH69
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

13689:I6G65 RS02515
gene id: 13689:I6G65_RS02515
uniprot id: A0A411LGG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

13689:I6G65 RS03010
gene id: 13689:I6G65_RS03010
uniprot id: A0A411LGY7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

13689:I6G65 RS14725
gene id: 13689:I6G65_RS14725
uniprot id: A0A411LMV2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

13689:I6G65 RS14080
gene id: 13689:I6G65_RS14080
uniprot id: A0A411LPC3
names: Similarity
messages: Belongs to the UPF0262 family.

13689:I6G65 RS15555
gene id: 13689:I6G65_RS15555
uniprot id: A0A411LE52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS17970
gene id: 13689:I6G65_RS17970
uniprot id: A0A411LF07
names: Similarity
messages: Belongs to the glutathione peroxidase family.

13689:I6G65 RS14060
gene id: 13689:I6G65_RS14060
uniprot id: A0A411LPF0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS08480
gene id: 13689:I6G65_RS08480
uniprot id: A0A411LJV6
names: Similarity
messages: Belongs to the GARS family.

13689:I6G65 RS17170
gene id: 13689:I6G65_RS17170
uniprot id: A0A411LEN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

13689:I6G65 RS13725
gene id: 13689:I6G65_RS13725
uniprot id: A0A411LMH1
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS14200
gene id: 13689:I6G65_RS14200
uniprot id: A0A411LMN4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

13689:I6G65 RS10265
gene id: 13689:I6G65_RS10265
uniprot id: A0A7Y2KNM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

13689:I6G65 RS10200
gene id: 13689:I6G65_RS10200
uniprot id: A0A411LKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS16145
gene id: 13689:I6G65_RS16145
uniprot id: A0A411LEF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS15635
gene id: 13689:I6G65_RS15635
uniprot id: A0A411LEB3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

13689:I6G65 RS18325
gene id: 13689:I6G65_RS18325
uniprot id: A0A411LF56
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

13689:I6G65 RS02390
gene id: 13689:I6G65_RS02390
uniprot id: A0A411LGE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

13689:I6G65 RS05900
gene id: 13689:I6G65_RS05900
uniprot id: A0A411LII6
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS14405
gene id: 13689:I6G65_RS14405
uniprot id: A0A411LPH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

13689:I6G65 RS08365
gene id: 13689:I6G65_RS08365
uniprot id: A0A411LJT3
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS06285
gene id: 13689:I6G65_RS06285
uniprot id: A0A411LIU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

13689:I6G65 RS08745
gene id: 13689:I6G65_RS08745
uniprot id: A0A411LK21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

13689:I6G65 RS08990
gene id: 13689:I6G65_RS08990
uniprot id: A0A411LK62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

13689:I6G65 RS02395
gene id: 13689:I6G65_RS02395
uniprot id: A0A411LNK3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS07100
gene id: 13689:I6G65_RS07100
uniprot id: A0A411LJ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

13689:I6G65 RS12950
gene id: 13689:I6G65_RS12950
uniprot id: A0A411LM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

13689:I6G65 RS08005
gene id: 13689:I6G65_RS08005
uniprot id: A0A411LJM2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

13689:I6G65 RS19665
gene id: 13689:I6G65_RS19665
uniprot id: A0A411LFD7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

13689:I6G65 RS18640
gene id: 13689:I6G65_RS18640
uniprot id: A0A411LFV7
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

13689:I6G65 RS04545
gene id: 13689:I6G65_RS04545
uniprot id: A0A411LHJ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

13689:I6G65 RS03580
gene id: 13689:I6G65_RS03580
uniprot id: A0A411LH52
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

13689:I6G65 RS10970
gene id: 13689:I6G65_RS10970
uniprot id: A0A411LL02
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

13689:I6G65 RS13715
gene id: 13689:I6G65_RS13715
uniprot id: A0A411LMC6
names: Function
messages: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.

13689:I6G65 RS18795
gene id: 13689:I6G65_RS18795
uniprot id: A0A411LNC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

13689:I6G65 RS04890
gene id: 13689:I6G65_RS04890
uniprot id: A0A411LHV9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

13689:I6G65 RS19060
gene id: 13689:I6G65_RS19060
uniprot id: A0A411LFL7
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS02415
gene id: 13689:I6G65_RS02415
uniprot id: A0A411LGI1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

13689:I6G65 RS09275
gene id: 13689:I6G65_RS09275
uniprot id: A0A411LK98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

13689:I6G65 RS16290
gene id: 13689:I6G65_RS16290
uniprot id: A0A411LEH3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

13689:I6G65 RS05035
gene id: 13689:I6G65_RS05035
uniprot id: A0A411LHZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

13689:I6G65 RS04580
gene id: 13689:I6G65_RS04580
uniprot id: A0A7T3E4T6
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS10635
gene id: 13689:I6G65_RS10635
uniprot id: A0A411LKV6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

13689:I6G65 RS14620
gene id: 13689:I6G65_RS14620
uniprot id: A0A411LMR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

13689:I6G65 RS13665
gene id: 13689:I6G65_RS13665
uniprot id: A0A411LMB8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS18250
gene id: 13689:I6G65_RS18250
uniprot id: A0A411LF55
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

13689:I6G65 RS15765
gene id: 13689:I6G65_RS15765
uniprot id: A0A411LEE0
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

13689:I6G65 RS16915
gene id: 13689:I6G65_RS16915
uniprot id: A0A7Y2KSD1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS10375
gene id: 13689:I6G65_RS10375
uniprot id: A0A411LKP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

13689:I6G65 RS06045
gene id: 13689:I6G65_RS06045
uniprot id: A0A411LIG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

13689:I6G65 RS09270
gene id: 13689:I6G65_RS09270
uniprot id: A0A7T3AAR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS00140
gene id: 13689:I6G65_RS00140
uniprot id: A0A7T3E909
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

13689:I6G65 RS03645
gene id: 13689:I6G65_RS03645
uniprot id: A0A411LHA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

13689:I6G65 RS14920
gene id: 13689:I6G65_RS14920
uniprot id: A0A7Y2KQV1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

13689:I6G65 RS14655
gene id: 13689:I6G65_RS14655
uniprot id: A0A411LMU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS06075
gene id: 13689:I6G65_RS06075
uniprot id: A0A411LIH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

13689:I6G65 RS01235
gene id: 13689:I6G65_RS01235
uniprot id: A0A7T3AEC8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.

13689:I6G65 RS11360
gene id: 13689:I6G65_RS11360
uniprot id: A0A411LL74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

13689:I6G65 RS10315
gene id: 13689:I6G65_RS10315
uniprot id: A0A411LKP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

13689:I6G65 RS02710
gene id: 13689:I6G65_RS02710
uniprot id: A0A411LGS7
names: Similarity
messages: Belongs to the thioredoxin family.

13689:I6G65 RS06750
gene id: 13689:I6G65_RS06750
uniprot id: A0A7T3ABA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

13689:I6G65 RS03815
gene id: 13689:I6G65_RS03815
uniprot id: A0A411LH91
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

13689:I6G65 RS03785
gene id: 13689:I6G65_RS03785
uniprot id: A0A411LHD7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

13689:I6G65 RS19835
gene id: 13689:I6G65_RS19835
uniprot id: A0A411LF99
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS06280
gene id: 13689:I6G65_RS06280
uniprot id: A0A411LIK5
names: Similarity
messages: Belongs to the PhzF family.

13689:I6G65 RS02180
gene id: 13689:I6G65_RS02180
uniprot id: A0A411LG77
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

13689:I6G65 RS02070
gene id: 13689:I6G65_RS02070
uniprot id: A0A411LG52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

13689:I6G65 RS04560
gene id: 13689:I6G65_RS04560
uniprot id: A0A411LHL2
names: Caution
names: Similarity
messages: Belongs to the YkuD family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS12040
gene id: 13689:I6G65_RS12040
uniprot id: A0A411LLJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS04440
gene id: 13689:I6G65_RS04440
uniprot id: A0A7Y2PCT4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS13975
gene id: 13689:I6G65_RS13975
uniprot id: A0A411LMI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

13689:I6G65 RS17730
gene id: 13689:I6G65_RS17730
uniprot id: A0A411LEW9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

13689:I6G65 RS12720
gene id: 13689:I6G65_RS12720
uniprot id: A0A7Y2PF36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

13689:I6G65 RS11655
gene id: 13689:I6G65_RS11655
uniprot id: A0A411LLB6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

13689:I6G65 RS15660
gene id: 13689:I6G65_RS15660
uniprot id: A0A411LEH2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

13689:I6G65 RS09810
gene id: 13689:I6G65_RS09810
uniprot id: A0A411LKH0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

13689:I6G65 RS18305
gene id: 13689:I6G65_RS18305
uniprot id: A0A411LF70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

13689:I6G65 RS04525
gene id: 13689:I6G65_RS04525
uniprot id: A0A411LHN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

13689:I6G65 RS13440
gene id: 13689:I6G65_RS13440
uniprot id: A0A411LM76
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

13689:I6G65 RS05250
gene id: 13689:I6G65_RS05250
uniprot id: A0A411LI11
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS10860
gene id: 13689:I6G65_RS10860
uniprot id: A0A411LL52
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

13689:I6G65 RS05435
gene id: 13689:I6G65_RS05435
uniprot id: A0A411LI47
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

13689:I6G65 RS13720
gene id: 13689:I6G65_RS13720
uniprot id: A0A411LMD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

13689:I6G65 RS14115
gene id: 13689:I6G65_RS14115
uniprot id: A0A411LMM4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

13689:I6G65 RS18290
gene id: 13689:I6G65_RS18290
uniprot id: A0A411LF61
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

13689:I6G65 RS05855
gene id: 13689:I6G65_RS05855
uniprot id: A0A411LIC9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

13689:I6G65 RS10440
gene id: 13689:I6G65_RS10440
uniprot id: A0A411LP03
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

13689:I6G65 RS07055
gene id: 13689:I6G65_RS07055
uniprot id: A0A411LIZ3
names: Similarity
messages: Belongs to the HIBADH-related family.

13689:I6G65 RS18505
gene id: 13689:I6G65_RS18505
uniprot id: A0A411LFX3
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

13689:I6G65 RS17940
gene id: 13689:I6G65_RS17940
uniprot id: A0A411LF03
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS08565
gene id: 13689:I6G65_RS08565
uniprot id: A0A411LJX0
names: Subcellular Location Annotation
messages: Mitochondrion

13689:I6G65 RS18465
gene id: 13689:I6G65_RS18465
uniprot id: A0A7Y2KQH1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

13689:I6G65 RS19825
gene id: 13689:I6G65_RS19825
uniprot id: A0A7Y2PDM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

13689:I6G65 RS17325
gene id: 13689:I6G65_RS17325
uniprot id: A0A7Y2KNS2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

13689:I6G65 RS05980
gene id: 13689:I6G65_RS05980
uniprot id: A0A411LIF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

13689:I6G65 RS03605
gene id: 13689:I6G65_RS03605
uniprot id: A0A411LHA6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

13689:I6G65 RS10580
gene id: 13689:I6G65_RS10580
uniprot id: A0A411LL03
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

13689:I6G65 RS02850
gene id: 13689:I6G65_RS02850
uniprot id: A0A411LGT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

13689:I6G65 RS05060
gene id: 13689:I6G65_RS05060
uniprot id: A0A411LI32
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS05460
gene id: 13689:I6G65_RS05460
uniprot id: A0A411LI49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

13689:I6G65 RS08945
gene id: 13689:I6G65_RS08945
uniprot id: A0A411LK37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

13689:I6G65 RS09400
gene id: 13689:I6G65_RS09400
uniprot id: A0A7T3AB30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

13689:I6G65 RS18830
gene id: 13689:I6G65_RS18830
uniprot id: A0A411LFQ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS19140
gene id: 13689:I6G65_RS19140
uniprot id: A0A411LNH4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS16750
gene id: 13689:I6G65_RS16750
uniprot id: A0A7T3A7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS12055
gene id: 13689:I6G65_RS12055
uniprot id: A0A411LLI9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS05770
gene id: 13689:I6G65_RS05770
uniprot id: A0A411LIG7
names: Similarity
messages: Belongs to the UPF0102 family.

13689:I6G65 RS05730
gene id: 13689:I6G65_RS05730
uniprot id: A0A411LIF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

13689:I6G65 RS15695
gene id: 13689:I6G65_RS15695
uniprot id: A0A411LED1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

13689:I6G65 RS08200
gene id: 13689:I6G65_RS08200
uniprot id: A0A411LJQ6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

13689:I6G65 RS15845
gene id: 13689:I6G65_RS15845
uniprot id: A0A411LEE8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

13689:I6G65 RS05095
gene id: 13689:I6G65_RS05095
uniprot id: A0A411LHY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

13689:I6G65 RS15785
gene id: 13689:I6G65_RS15785
uniprot id: A0A411LEJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

13689:I6G65 RS12805
gene id: 13689:I6G65_RS12805
uniprot id: A0A411LLX2
names: Similarity
messages: Belongs to the RelE toxin family.

13689:I6G65 RS05745
gene id: 13689:I6G65_RS05745
uniprot id: A0A411LID4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

13689:I6G65 RS14070
gene id: 13689:I6G65_RS14070
uniprot id: A0A411LMJ0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

13689:I6G65 RS19020
gene id: 13689:I6G65_RS19020
uniprot id: A0A411LFN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

13689:I6G65 RS04180
gene id: 13689:I6G65_RS04180
uniprot id: A0A411LHH7
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

13689:I6G65 RS18010
gene id: 13689:I6G65_RS18010
uniprot id: A0A411LF26
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

13689:I6G65 RS13555
gene id: 13689:I6G65_RS13555
uniprot id: A0A411LME1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS19725
gene id: 13689:I6G65_RS19725
uniprot id: A0A411LFC8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

13689:I6G65 RS19850
gene id: 13689:I6G65_RS19850
uniprot id: A0A411LF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS10995
gene id: 13689:I6G65_RS10995
uniprot id: A0A411LL18
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

13689:I6G65 RS10975
gene id: 13689:I6G65_RS10975
uniprot id: A0A7Y2PC96
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS14130
gene id: 13689:I6G65_RS14130
uniprot id: A0A411LMK8
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

13689:I6G65 RS02410
gene id: 13689:I6G65_RS02410
uniprot id: A0A411LGI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

13689:I6G65 RS08655
gene id: 13689:I6G65_RS08655
uniprot id: A0A411LJZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

13689:I6G65 RS02120
gene id: 13689:I6G65_RS02120
uniprot id: A0A411LG67
names: Similarity
messages: Belongs to the UPF0246 family.

13689:I6G65 RS03205
gene id: 13689:I6G65_RS03205
uniprot id: A0A411LGW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

13689:I6G65 RS06625
gene id: 13689:I6G65_RS06625
uniprot id: A0A411LIR6
names: Similarity
messages: Belongs to the peptidase U62 family.

13689:I6G65 RS19160
gene id: 13689:I6G65_RS19160
uniprot id: A0A411LFL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

13689:I6G65 RS00770
gene id: 13689:I6G65_RS00770
uniprot id: A0A7Y2PBP3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS08860
gene id: 13689:I6G65_RS08860
uniprot id: A0A411LK23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

13689:I6G65 RS05875
gene id: 13689:I6G65_RS05875
uniprot id: A0A411LID1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

13689:I6G65 RS06025
gene id: 13689:I6G65_RS06025
uniprot id: A0A411LIG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

13689:I6G65 RS02875
gene id: 13689:I6G65_RS02875
uniprot id: A0A411LGY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS13955
gene id: 13689:I6G65_RS13955
uniprot id: A0A411LPE3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS08105
gene id: 13689:I6G65_RS08105
uniprot id: A0A411LJP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

13689:I6G65 RS19530
gene id: 13689:I6G65_RS19530
uniprot id: A0A411LFE2
names: Similarity
messages: Belongs to the FrmR/RcnR family.

13689:I6G65 RS08695
gene id: 13689:I6G65_RS08695
uniprot id: A0A411LJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

13689:I6G65 RS17915
gene id: 13689:I6G65_RS17915
uniprot id: A0A411LEZ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS11950
gene id: 13689:I6G65_RS11950
uniprot id: A0A7Y2KQQ9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

13689:I6G65 RS19065
gene id: 13689:I6G65_RS19065
uniprot id: A0A411LFN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

13689:I6G65 RS11565
gene id: 13689:I6G65_RS11565
uniprot id: A0A411LLB1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS01610
gene id: 13689:I6G65_RS01610
uniprot id: A0A031J272
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

13689:I6G65 RS10960
gene id: 13689:I6G65_RS10960
uniprot id: A0A411LL04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS17920
gene id: 13689:I6G65_RS17920
uniprot id: A0A411LEZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

13689:I6G65 RS08410
gene id: 13689:I6G65_RS08410
uniprot id: A0A411LJT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

13689:I6G65 RS12625
gene id: 13689:I6G65_RS12625
uniprot id: A0A7T3AC19
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

13689:I6G65 RS02765
gene id: 13689:I6G65_RS02765
uniprot id: A0A411LGT9
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

13689:I6G65 RS05625
gene id: 13689:I6G65_RS05625
uniprot id: A0A411LID2
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS12250
gene id: 13689:I6G65_RS12250
uniprot id: A0A411LLL8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

13689:I6G65 RS03440
gene id: 13689:I6G65_RS03440
uniprot id: A0A411LH50
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

13689:I6G65 RS19460
gene id: 13689:I6G65_RS19460
uniprot id: A0A411LFL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

13689:I6G65 RS06835
gene id: 13689:I6G65_RS06835
uniprot id: A0A7T3A9W7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS06920
gene id: 13689:I6G65_RS06920
uniprot id: A0A411LIZ9
names: Similarity
messages: Belongs to the peptidase S41A family.

13689:I6G65 RS14470
gene id: 13689:I6G65_RS14470
uniprot id: A0A411LMR5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

13689:I6G65 RS08190
gene id: 13689:I6G65_RS08190
uniprot id: A0A411LJQ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

13689:I6G65 RS14335
gene id: 13689:I6G65_RS14335
uniprot id: A0A7T3ACR6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

13689:I6G65 RS15470
gene id: 13689:I6G65_RS15470
uniprot id: A0A411LN71
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

13689:I6G65 RS14710
gene id: 13689:I6G65_RS14710
uniprot id: A0A411LMW0
names: Similarity
messages: Belongs to the HesB/IscA family.

13689:I6G65 RS17165
gene id: 13689:I6G65_RS17165
uniprot id: A0A7T3E3Y7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

13689:I6G65 RS17080
gene id: 13689:I6G65_RS17080
uniprot id: A0A411LER8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

13689:I6G65 RS09530
gene id: 13689:I6G65_RS09530
uniprot id: A0A411LKC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

13689:I6G65 RS07435
gene id: 13689:I6G65_RS07435
uniprot id: A0A411LNX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

13689:I6G65 RS14900
gene id: 13689:I6G65_RS14900
uniprot id: A0A411LMS7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS01025
gene id: 13689:I6G65_RS01025
uniprot id: A0A7T3AED4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

13689:I6G65 RS17160
gene id: 13689:I6G65_RS17160
uniprot id: A0A411LEN6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

13689:I6G65 RS10355
gene id: 13689:I6G65_RS10355
uniprot id: A0A411LKQ7
names: Similarity
messages: Belongs to the UPF0174 family.

13689:I6G65 RS02885
gene id: 13689:I6G65_RS02885
uniprot id: A0A411LGS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

13689:I6G65 RS14680
gene id: 13689:I6G65_RS14680
uniprot id: A0A411LMX2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

13689:I6G65 RS11905
gene id: 13689:I6G65_RS11905
uniprot id: A0A411LLM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS09005
gene id: 13689:I6G65_RS09005
uniprot id: A0A411LK47
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

13689:I6G65 RS02200
gene id: 13689:I6G65_RS02200
uniprot id: A0A411LG56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

13689:I6G65 RS19015
gene id: 13689:I6G65_RS19015
uniprot id: A0A411LFP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

13689:I6G65 RS14730
gene id: 13689:I6G65_RS14730
uniprot id: A0A411LMV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

13689:I6G65 RS10935
gene id: 13689:I6G65_RS10935
uniprot id: A0A411LKY7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS02090
gene id: 13689:I6G65_RS02090
uniprot id: A0A411LG35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

13689:I6G65 RS13935
gene id: 13689:I6G65_RS13935
uniprot id: A0A411LMH2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS02010
gene id: 13689:I6G65_RS02010
uniprot id: A0A411LG43
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

13689:I6G65 RS02375
gene id: 13689:I6G65_RS02375
uniprot id: A0A411LGH5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS17270
gene id: 13689:I6G65_RS17270
uniprot id: A0A411LEQ5
names: Similarity
messages: Belongs to the RNase T2 family.

13689:I6G65 RS12870
gene id: 13689:I6G65_RS12870
uniprot id: A0A411LLY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS12550
gene id: 13689:I6G65_RS12550
uniprot id: A0A411LLS8
names: Similarity
messages: Belongs to the aldose epimerase family.

13689:I6G65 RS07240
gene id: 13689:I6G65_RS07240
uniprot id: A0A411LJ18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

13689:I6G65 RS18280
gene id: 13689:I6G65_RS18280
uniprot id: A0A411LFB3
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS18270
gene id: 13689:I6G65_RS18270
uniprot id: A0A411LF54
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

13689:I6G65 RS06070
gene id: 13689:I6G65_RS06070
uniprot id: A0A411LII0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

13689:I6G65 RS06930
gene id: 13689:I6G65_RS06930
uniprot id: A0A411LIX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

13689:I6G65 RS10750
gene id: 13689:I6G65_RS10750
uniprot id: A0A411LL32
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

13689:I6G65 RS05950
gene id: 13689:I6G65_RS05950
uniprot id: A0A411LIJ3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS17400
gene id: 13689:I6G65_RS17400
uniprot id: A0A411LER4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

13689:I6G65 RS08780
gene id: 13689:I6G65_RS08780
uniprot id: A0A411LK11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

13689:I6G65 RS17935
gene id: 13689:I6G65_RS17935
uniprot id: A0A411LF57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

13689:I6G65 RS05820
gene id: 13689:I6G65_RS05820
uniprot id: A0A411LIH7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

13689:I6G65 RS13460
gene id: 13689:I6G65_RS13460
uniprot id: A0A411LM87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

13689:I6G65 RS01495
gene id: 13689:I6G65_RS01495
uniprot id: A0A7T3AEA6
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS09035
gene id: 13689:I6G65_RS09035
uniprot id: A0A411LK48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

13689:I6G65 RS13875
gene id: 13689:I6G65_RS13875
uniprot id: A0A411LMH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

13689:I6G65 RS12310
gene id: 13689:I6G65_RS12310
uniprot id: A0A411LLL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS12270
gene id: 13689:I6G65_RS12270
uniprot id: A0A411LLM6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

13689:I6G65 RS05315
gene id: 13689:I6G65_RS05315
uniprot id: A0A411LI75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

13689:I6G65 RS07005
gene id: 13689:I6G65_RS07005
uniprot id: A0A7Y2KN88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

13689:I6G65 RS19305
gene id: 13689:I6G65_RS19305
uniprot id: A0A411LFJ2
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

13689:I6G65 RS13065
gene id: 13689:I6G65_RS13065
uniprot id: A0A411LM57
names: Similarity
messages: Belongs to the pyruvate kinase family.

13689:I6G65 RS13365
gene id: 13689:I6G65_RS13365
uniprot id: A0A411LM74
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

13689:I6G65 RS06725
gene id: 13689:I6G65_RS06725
uniprot id: A0A411LIX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

13689:I6G65 RS18620
gene id: 13689:I6G65_RS18620
uniprot id: A0A411LFV3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS10535
gene id: 13689:I6G65_RS10535
uniprot id: A0A411LKT2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

13689:I6G65 RS09370
gene id: 13689:I6G65_RS09370
uniprot id: A0A411LKA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS12010
gene id: 13689:I6G65_RS12010
uniprot id: A0A7T3ABS8
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

13689:I6G65 RS09915
gene id: 13689:I6G65_RS09915
uniprot id: A0A411LKJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS01835
gene id: 13689:I6G65_RS01835
uniprot id: A0A7Y2KQX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS01755
gene id: 13689:I6G65_RS01755
uniprot id: A0A7T3AE28
names: Similarity
messages: Belongs to the FrmR/RcnR family.

13689:I6G65 RS01490
gene id: 13689:I6G65_RS01490
uniprot id: A0A7T3AE48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Periplasm

13689:I6G65 RS04435
gene id: 13689:I6G65_RS04435
uniprot id: A0A411LHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS08950
gene id: 13689:I6G65_RS08950
uniprot id: A0A411LK44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

13689:I6G65 RS12725
gene id: 13689:I6G65_RS12725
uniprot id: A0A411LLX0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS07220
gene id: 13689:I6G65_RS07220
uniprot id: A0A411LNZ6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

13689:I6G65 RS11510
gene id: 13689:I6G65_RS11510
uniprot id: A0A411LLF2
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS16930
gene id: 13689:I6G65_RS16930
uniprot id: A0A7Y2KRQ6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS18350
gene id: 13689:I6G65_RS18350
uniprot id: A0A411LF74
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS13625
gene id: 13689:I6G65_RS13625
uniprot id: A0A411LMC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

13689:I6G65 RS15375
gene id: 13689:I6G65_RS15375
uniprot id: A0A411LN45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS05695
gene id: 13689:I6G65_RS05695
uniprot id: A0A411LI98
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

13689:I6G65 RS04415
gene id: 13689:I6G65_RS04415
uniprot id: A0A7T3E6K4
names: Similarity
messages: Belongs to the MQO family.

13689:I6G65 RS14610
gene id: 13689:I6G65_RS14610
uniprot id: A0A411LMW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

13689:I6G65 RS01500
gene id: 13689:I6G65_RS01500
uniprot id: A0A7T3E938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

13689:I6G65 RS12445
gene id: 13689:I6G65_RS12445
uniprot id: A0A411LLQ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

13689:I6G65 RS13100
gene id: 13689:I6G65_RS13100
uniprot id: A0A411LM33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

13689:I6G65 RS18635
gene id: 13689:I6G65_RS18635
uniprot id: A0A411LFW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

13689:I6G65 RS16375
gene id: 13689:I6G65_RS16375
uniprot id: A0A411LEJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

13689:I6G65 RS13870
gene id: 13689:I6G65_RS13870
uniprot id: A0A411LMC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

13689:I6G65 RS06945
gene id: 13689:I6G65_RS06945
uniprot id: A0A411LIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

13689:I6G65 RS11255
gene id: 13689:I6G65_RS11255
uniprot id: A0A411LL62
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS06335
gene id: 13689:I6G65_RS06335
uniprot id: A0A7T3E6L4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

13689:I6G65 RS06450
gene id: 13689:I6G65_RS06450
uniprot id: A0A411LIP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

13689:I6G65 RS13110
gene id: 13689:I6G65_RS13110
uniprot id: A0A411LM19
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

13689:I6G65 RS05680
gene id: 13689:I6G65_RS05680
uniprot id: A0A411LIE6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

13689:I6G65 RS19895
gene id: 13689:I6G65_RS19895
uniprot id: A0A7T3E660
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

13689:I6G65 RS14270
gene id: 13689:I6G65_RS14270
uniprot id: A0A411LMI4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

13689:I6G65 RS06055
gene id: 13689:I6G65_RS06055
uniprot id: A0A411LIK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

13689:I6G65 RS08815
gene id: 13689:I6G65_RS08815
uniprot id: A0A411LK22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

13689:I6G65 RS07550
gene id: 13689:I6G65_RS07550
uniprot id: A0A411LJA1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

13689:I6G65 RS05965
gene id: 13689:I6G65_RS05965
uniprot id: A0A411LIF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

13689:I6G65 RS10940
gene id: 13689:I6G65_RS10940
uniprot id: A0A411LL00
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS07395
gene id: 13689:I6G65_RS07395
uniprot id: A0A411LJ51
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS03820
gene id: 13689:I6G65_RS03820
uniprot id: A0A411LHD3
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

13689:I6G65 RS19905
gene id: 13689:I6G65_RS19905
uniprot id: A0A411LF95
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

13689:I6G65 RS12740
gene id: 13689:I6G65_RS12740
uniprot id: A0A411LLW3
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

13689:I6G65 RS09970
gene id: 13689:I6G65_RS09970
uniprot id: A0A411LKR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

13689:I6G65 RS18550
gene id: 13689:I6G65_RS18550
uniprot id: A0A411LFX8
names: Similarity
messages: Belongs to the virb1 family.

13689:I6G65 RS01210
gene id: 13689:I6G65_RS01210
uniprot id: A0A7T3E6U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

13689:I6G65 RS03675
gene id: 13689:I6G65_RS03675
uniprot id: A0A411LHB6
names: Similarity
messages: Belongs to the PspA/IM30 family.

13689:I6G65 RS10670
gene id: 13689:I6G65_RS10670
uniprot id: A0A411LKV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

13689:I6G65 RS15325
gene id: 13689:I6G65_RS15325
uniprot id: A0A411LN78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS01310
gene id: 13689:I6G65_RS01310
uniprot id: A0A7T3AE89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

13689:I6G65 RS13215
gene id: 13689:I6G65_RS13215
uniprot id: A0A7T3AC91
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

13689:I6G65 RS14565
gene id: 13689:I6G65_RS14565
uniprot id: A0A411LMQ8
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS19155
gene id: 13689:I6G65_RS19155
uniprot id: A0A411LFM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

13689:I6G65 RS07140
gene id: 13689:I6G65_RS07140
uniprot id: A0A411LJ24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

13689:I6G65 RS16680
gene id: 13689:I6G65_RS16680
uniprot id: A0A7T3A8H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

13689:I6G65 RS17995
gene id: 13689:I6G65_RS17995
uniprot id: A0A411LF13
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

13689:I6G65 RS16195
gene id: 13689:I6G65_RS16195
uniprot id: A0A411LEG3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

13689:I6G65 RS06910
gene id: 13689:I6G65_RS06910
uniprot id: A0A411LJ28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

13689:I6G65 RS17845
gene id: 13689:I6G65_RS17845
uniprot id: A0A411LEY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

13689:I6G65 RS10305
gene id: 13689:I6G65_RS10305
uniprot id: A0A411LKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

13689:I6G65 RS03685
gene id: 13689:I6G65_RS03685
uniprot id: A0A411LH61
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS04955
gene id: 13689:I6G65_RS04955
uniprot id: A0A411LI13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

13689:I6G65 RS11695
gene id: 13689:I6G65_RS11695
uniprot id: A0A411LLD0
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

13689:I6G65 RS08475
gene id: 13689:I6G65_RS08475
uniprot id: A0A7T3E6A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

13689:I6G65 RS13635
gene id: 13689:I6G65_RS13635
uniprot id: A0A411LM82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

13689:I6G65 RS09880
gene id: 13689:I6G65_RS09880
uniprot id: A0A411LKI5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

13689:I6G65 RS13930
gene id: 13689:I6G65_RS13930
uniprot id: A0A411LMI0
names: Similarity
messages: Belongs to the OprB family.

13689:I6G65 RS11785
gene id: 13689:I6G65_RS11785
uniprot id: A0A411LLC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

13689:I6G65 RS13605
gene id: 13689:I6G65_RS13605
uniprot id: A0A411LMA1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

13689:I6G65 RS01205
gene id: 13689:I6G65_RS01205
uniprot id: A0A7T3E7A2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

13689:I6G65 RS19455
gene id: 13689:I6G65_RS19455
uniprot id: A0A411LFF4
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS11485
gene id: 13689:I6G65_RS11485
uniprot id: A0A7Y2KMN3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS06100
gene id: 13689:I6G65_RS06100
uniprot id: A0A411LIR7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

13689:I6G65 RS15550
gene id: 13689:I6G65_RS15550
uniprot id: A0A411LN83
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

13689:I6G65 RS09640
gene id: 13689:I6G65_RS09640
uniprot id: A0A411LKE0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

13689:I6G65 RS19630
gene id: 13689:I6G65_RS19630
uniprot id: A0A411LFD5
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

13689:I6G65 RS02670
gene id: 13689:I6G65_RS02670
uniprot id: A0A411LGP5
names: Similarity
messages: Belongs to the UPF0047 family.

13689:I6G65 RS07520
gene id: 13689:I6G65_RS07520
uniprot id: A0A411LJC1
names: Similarity
messages: Belongs to the FBPase class 2 family.

13689:I6G65 RS05240
gene id: 13689:I6G65_RS05240
uniprot id: A0A411LI24
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS13945
gene id: 13689:I6G65_RS13945
uniprot id: A0A411LMG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

13689:I6G65 RS03535
gene id: 13689:I6G65_RS03535
uniprot id: A0A411LH84
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

13689:I6G65 RS01860
gene id: 13689:I6G65_RS01860
uniprot id: A0A411LG18
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

13689:I6G65 RS01155
gene id: 13689:I6G65_RS01155
uniprot id: A0A7T3AED9
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

13689:I6G65 RS17150
gene id: 13689:I6G65_RS17150
uniprot id: A0A411LEN7
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

13689:I6G65 RS03055
gene id: 13689:I6G65_RS03055
uniprot id: A0A411LGV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

13689:I6G65 RS03530
gene id: 13689:I6G65_RS03530
uniprot id: A0A411LH42
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS03730
gene id: 13689:I6G65_RS03730
uniprot id: A0A411LHC7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

13689:I6G65 RS02550
gene id: 13689:I6G65_RS02550
uniprot id: A0A411LGM0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

13689:I6G65 RS17295
gene id: 13689:I6G65_RS17295
uniprot id: A0A411LEQ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

13689:I6G65 RS16440
gene id: 13689:I6G65_RS16440
uniprot id: A0A411LEK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

13689:I6G65 RS18355
gene id: 13689:I6G65_RS18355
uniprot id: A0A411LF80
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

13689:I6G65 RS01425
gene id: 13689:I6G65_RS01425
uniprot id: A0A7T3AE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

13689:I6G65 RS16250
gene id: 13689:I6G65_RS16250
uniprot id: A0A411LEH8
names: Similarity
messages: Belongs to the YkuD family.

13689:I6G65 RS10485
gene id: 13689:I6G65_RS10485
uniprot id: A0A411LKS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

13689:I6G65 RS06000
gene id: 13689:I6G65_RS06000
uniprot id: A0A411LIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

13689:I6G65 RS13300
gene id: 13689:I6G65_RS13300
uniprot id: A0A411LM25
names: Subcellular Location Annotation
messages: Nucleus

13689:I6G65 RS19355
gene id: 13689:I6G65_RS19355
uniprot id: A0A411LNG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

13689:I6G65 RS15805
gene id: 13689:I6G65_RS15805
uniprot id: A0A411LEE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

13689:I6G65 RS15195
gene id: 13689:I6G65_RS15195
uniprot id: A0A411LN36
names: Subcellular Location Annotation
messages: Membrane

13689:I6G65 RS20395
gene id: 13689:I6G65_RS20395
uniprot id: A0A7Y2KRT6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS09405
gene id: 13689:I6G65_RS09405
uniprot id: A0A411LKA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

13689:I6G65 RS05550
gene id: 13689:I6G65_RS05550
uniprot id: A0A411LIA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

13689:I6G65 RS01985
gene id: 13689:I6G65_RS01985
uniprot id: A0A411LG11
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

13689:I6G65 RS14545
gene id: 13689:I6G65_RS14545
uniprot id: A0A411LPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

13689:I6G65 RS03095
gene id: 13689:I6G65_RS03095
uniprot id: A0A411LGZ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

13689:I6G65 RS10540
gene id: 13689:I6G65_RS10540
uniprot id: A0A411LKS9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

13689:I6G65 RS18660
gene id: 13689:I6G65_RS18660
uniprot id: A0A411LFT7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

13689:I6G65 RS03035
gene id: 13689:I6G65_RS03035
uniprot id: A0A411LGZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

13689:I6G65 RS05375
gene id: 13689:I6G65_RS05375
uniprot id: A0A411LI51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

13689:I6G65 RS06235
gene id: 13689:I6G65_RS06235
uniprot id: A0A411LIP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

13689:I6G65 RS08165
gene id: 13689:I6G65_RS08165
uniprot id: A0A411LJQ1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

13689:I6G65 RS06035
gene id: 13689:I6G65_RS06035
uniprot id: A0A411LIH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

13689:I6G65 RS04345
gene id: 13689:I6G65_RS04345
uniprot id: A0A411LHH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

13689:I6G65 RS12545
gene id: 13689:I6G65_RS12545
uniprot id: A0A411LLQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

13689:I6G65 RS11075
gene id: 13689:I6G65_RS11075
uniprot id: A0A411LL30
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the maleate isomerase family.
messages: Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
messages: Homodimer.
messages: Reaction is initiated by nucleophilic attack of cysteine at the double bond, yielding a covalent succinylcysteine-like intermediate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

13689:I6G65 RS18130
gene id: 13689:I6G65_RS18130
uniprot id: A0A411LF37
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

13689:I6G65 RS07205
gene id: 13689:I6G65_RS07205
uniprot id: A0A411LJ22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

13689:I6G65 RS10800
gene id: 13689:I6G65_RS10800
uniprot id: A0A411LKY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

13689:I6G65 RS03245
gene id: 13689:I6G65_RS03245
uniprot id: A0A411LGX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

13689:I6G65 RS01430
gene id: 13689:I6G65_RS01430
uniprot id: A0A7T3AFK0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.