135719:SAMIE RS09640
gene id: 135719:SAMIE_RS09640
uniprot id: A0A494W4W0
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

135719:SAMIE RS11925
gene id: 135719:SAMIE_RS11925
uniprot id: A0A494WDX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

135719:SAMIE RS21080
gene id: 135719:SAMIE_RS21080
uniprot id: A0A494W7L3
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS04725
gene id: 135719:SAMIE_RS04725
uniprot id: A0A494WAU9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

135719:SAMIE RS18790
gene id: 135719:SAMIE_RS18790
uniprot id: A0A494WAY5
names: Similarity
messages: Belongs to the UPF0111 family.

135719:SAMIE RS08225
gene id: 135719:SAMIE_RS08225
uniprot id: A0A494W187
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

135719:SAMIE RS08190
gene id: 135719:SAMIE_RS08190
uniprot id: A0A494WBR3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

135719:SAMIE RS03915
gene id: 135719:SAMIE_RS03915
uniprot id: A0A494W1J4
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS01670
gene id: 135719:SAMIE_RS01670
uniprot id: A0A494W080
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS03030
gene id: 135719:SAMIE_RS03030
uniprot id: A0A494VXC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

135719:SAMIE RS03375
gene id: 135719:SAMIE_RS03375
uniprot id: A0A494VXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

135719:SAMIE RS13940
gene id: 135719:SAMIE_RS13940
uniprot id: A0A494WDN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

135719:SAMIE RS18780
gene id: 135719:SAMIE_RS18780
uniprot id: A0A494WG13
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

135719:SAMIE RS03180
gene id: 135719:SAMIE_RS03180
uniprot id: A0A494VYX2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

135719:SAMIE RS14465
gene id: 135719:SAMIE_RS14465
uniprot id: A0A494WE85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

135719:SAMIE RS13600
gene id: 135719:SAMIE_RS13600
uniprot id: A0A494WDI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

135719:SAMIE RS19430
gene id: 135719:SAMIE_RS19430
uniprot id: A0A494WG99
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

135719:SAMIE RS01715
gene id: 135719:SAMIE_RS01715
uniprot id: A0A494VWL6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS00185
gene id: 135719:SAMIE_RS00185
uniprot id: A0A494VVV2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

135719:SAMIE RS05335
gene id: 135719:SAMIE_RS05335
uniprot id: A0A494VYF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

135719:SAMIE RS06325
gene id: 135719:SAMIE_RS06325
uniprot id: A0A494WAU3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

135719:SAMIE RS16105
gene id: 135719:SAMIE_RS16105
uniprot id: A0A494W864
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

135719:SAMIE RS11450
gene id: 135719:SAMIE_RS11450
uniprot id: A0A494W1P5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

135719:SAMIE RS02070
gene id: 135719:SAMIE_RS02070
uniprot id: A0A494W114
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

135719:SAMIE RS00550
gene id: 135719:SAMIE_RS00550
uniprot id: A0A494W7K5
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

135719:SAMIE RS17875
gene id: 135719:SAMIE_RS17875
uniprot id: A0A494W8M4
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS15970
gene id: 135719:SAMIE_RS15970
uniprot id: A0A494W402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

135719:SAMIE RS06415
gene id: 135719:SAMIE_RS06415
uniprot id: A0A494WAW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS14555
gene id: 135719:SAMIE_RS14555
uniprot id: A0A494W398
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

135719:SAMIE RS14430
gene id: 135719:SAMIE_RS14430
uniprot id: A0A494W7D4
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

135719:SAMIE RS19145
gene id: 135719:SAMIE_RS19145
uniprot id: A0A494W5Q6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

135719:SAMIE RS02295
gene id: 135719:SAMIE_RS02295
uniprot id: A0A494W145
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS20820
gene id: 135719:SAMIE_RS20820
uniprot id: A0A494WH79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

135719:SAMIE RS16740
gene id: 135719:SAMIE_RS16740
uniprot id: A0A494WF87
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

135719:SAMIE RS13585
gene id: 135719:SAMIE_RS13585
uniprot id: A0A494W6T2
names: Similarity
messages: Belongs to the type III secretion exporter family.

135719:SAMIE RS05850
gene id: 135719:SAMIE_RS05850
uniprot id: A0A494W4L8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

135719:SAMIE RS14790
gene id: 135719:SAMIE_RS14790
uniprot id: A0A494W7K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

135719:SAMIE RS16135
gene id: 135719:SAMIE_RS16135
uniprot id: A0A494W494
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

135719:SAMIE RS00920
gene id: 135719:SAMIE_RS00920
uniprot id: A0A494W0G6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS07680
gene id: 135719:SAMIE_RS07680
uniprot id: A0A494W3F8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

135719:SAMIE RS18240
gene id: 135719:SAMIE_RS18240
uniprot id: A0A494W8T3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

135719:SAMIE RS03870
gene id: 135719:SAMIE_RS03870
uniprot id: A0A494W1Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

135719:SAMIE RS06255
gene id: 135719:SAMIE_RS06255
uniprot id: A0A494WAU4
names: Similarity
messages: Belongs to the universal stress protein A family.

135719:SAMIE RS07390
gene id: 135719:SAMIE_RS07390
uniprot id: A0A494W5G4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

135719:SAMIE RS17195
gene id: 135719:SAMIE_RS17195
uniprot id: A0A494WF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

135719:SAMIE RS22700
gene id: 135719:SAMIE_RS22700
uniprot id: A0A494W7I6
names: Similarity
messages: Belongs to the YciI family.

135719:SAMIE RS07785
gene id: 135719:SAMIE_RS07785
uniprot id: A0A494VZP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

135719:SAMIE RS18200
gene id: 135719:SAMIE_RS18200
uniprot id: A0A494W993
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS13410
gene id: 135719:SAMIE_RS13410
uniprot id: A0A494W7L6
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

135719:SAMIE RS12845
gene id: 135719:SAMIE_RS12845
uniprot id: A0A494WDI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

135719:SAMIE RS11570
gene id: 135719:SAMIE_RS11570
uniprot id: A0A494W7K8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

135719:SAMIE RS04275
gene id: 135719:SAMIE_RS04275
uniprot id: A0A494VXZ9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

135719:SAMIE RS07485
gene id: 135719:SAMIE_RS07485
uniprot id: A0A494WBC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

135719:SAMIE RS14295
gene id: 135719:SAMIE_RS14295
uniprot id: A0A494WE63
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

135719:SAMIE RS08470
gene id: 135719:SAMIE_RS08470
uniprot id: A0A494W629
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

135719:SAMIE RS11680
gene id: 135719:SAMIE_RS11680
uniprot id: A0A494W5H8
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS14270
gene id: 135719:SAMIE_RS14270
uniprot id: A0A494WDS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

135719:SAMIE RS05715
gene id: 135719:SAMIE_RS05715
uniprot id: A0A494WAN0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS02155
gene id: 135719:SAMIE_RS02155
uniprot id: A0A494VWU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

135719:SAMIE RS10280
gene id: 135719:SAMIE_RS10280
uniprot id: A0A494W4R5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

135719:SAMIE RS03260
gene id: 135719:SAMIE_RS03260
uniprot id: A0A494W194
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

135719:SAMIE RS07380
gene id: 135719:SAMIE_RS07380
uniprot id: A0A494WBC0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

135719:SAMIE RS04255
gene id: 135719:SAMIE_RS04255
uniprot id: A0A494W9D3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

135719:SAMIE RS11740
gene id: 135719:SAMIE_RS11740
uniprot id: A0A494W5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

135719:SAMIE RS18870
gene id: 135719:SAMIE_RS18870
uniprot id: A0A494WFW5
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

135719:SAMIE RS02435
gene id: 135719:SAMIE_RS02435
uniprot id: A0A494VX08
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

135719:SAMIE RS19765
gene id: 135719:SAMIE_RS19765
uniprot id: A0A494WBF4
names: Similarity
messages: Belongs to the GSP E family.

135719:SAMIE RS12650
gene id: 135719:SAMIE_RS12650
uniprot id: A0A494W289
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

135719:SAMIE RS14015
gene id: 135719:SAMIE_RS14015
uniprot id: A0A494W366
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

135719:SAMIE RS04295
gene id: 135719:SAMIE_RS04295
uniprot id: A0A494W287
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

135719:SAMIE RS20005
gene id: 135719:SAMIE_RS20005
uniprot id: A0A494W9Q6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

135719:SAMIE RS10235
gene id: 135719:SAMIE_RS10235
uniprot id: A0A494WD88
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

135719:SAMIE RS19120
gene id: 135719:SAMIE_RS19120
uniprot id: A0A494W9R6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

135719:SAMIE RS12580
gene id: 135719:SAMIE_RS12580
uniprot id: A0A494WDE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

135719:SAMIE RS05860
gene id: 135719:SAMIE_RS05860
uniprot id: A0A494WBB2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS06520
gene id: 135719:SAMIE_RS06520
uniprot id: A0A494WBL4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

135719:SAMIE RS22030
gene id: 135719:SAMIE_RS22030
uniprot id: A0A494W830
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

135719:SAMIE RS11860
gene id: 135719:SAMIE_RS11860
uniprot id: A0A494W7R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

135719:SAMIE RS13770
gene id: 135719:SAMIE_RS13770
uniprot id: A0A494WDW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

135719:SAMIE RS19445
gene id: 135719:SAMIE_RS19445
uniprot id: A0A494W9Y3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

135719:SAMIE RS20620
gene id: 135719:SAMIE_RS20620
uniprot id: A0A494WA01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS11175
gene id: 135719:SAMIE_RS11175
uniprot id: A0A494W589
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

135719:SAMIE RS07985
gene id: 135719:SAMIE_RS07985
uniprot id: A0A494WAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

135719:SAMIE RS16440
gene id: 135719:SAMIE_RS16440
uniprot id: A0A494W496
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

135719:SAMIE RS13955
gene id: 135719:SAMIE_RS13955
uniprot id: A0A494W2Y2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

135719:SAMIE RS00705
gene id: 135719:SAMIE_RS00705
uniprot id: A0A494W882
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS14275
gene id: 135719:SAMIE_RS14275
uniprot id: A0A494W491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

135719:SAMIE RS09670
gene id: 135719:SAMIE_RS09670
uniprot id: A0A494W0T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS15960
gene id: 135719:SAMIE_RS15960
uniprot id: A0A494W529
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

135719:SAMIE RS09320
gene id: 135719:SAMIE_RS09320
uniprot id: A0A494W0M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

135719:SAMIE RS07100
gene id: 135719:SAMIE_RS07100
uniprot id: A0A494WB70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

135719:SAMIE RS09410
gene id: 135719:SAMIE_RS09410
uniprot id: A0A494W4R9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS16215
gene id: 135719:SAMIE_RS16215
uniprot id: A0A494WEL4
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

135719:SAMIE RS15025
gene id: 135719:SAMIE_RS15025
uniprot id: A0A494W4M4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

135719:SAMIE RS16780
gene id: 135719:SAMIE_RS16780
uniprot id: A0A494WF39
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

135719:SAMIE RS15915
gene id: 135719:SAMIE_RS15915
uniprot id: A0A494W7L9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

135719:SAMIE RS08480
gene id: 135719:SAMIE_RS08480
uniprot id: A0A494W4B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

135719:SAMIE RS18650
gene id: 135719:SAMIE_RS18650
uniprot id: A0A494WFT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

135719:SAMIE RS00865
gene id: 135719:SAMIE_RS00865
uniprot id: A0A494W244
names: Similarity
messages: Belongs to the ParB family.

135719:SAMIE RS05480
gene id: 135719:SAMIE_RS05480
uniprot id: A0A494W2U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

135719:SAMIE RS17980
gene id: 135719:SAMIE_RS17980
uniprot id: A0A494W554
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

135719:SAMIE RS12725
gene id: 135719:SAMIE_RS12725
uniprot id: A0A494WE90
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS07115
gene id: 135719:SAMIE_RS07115
uniprot id: A0A494W5B4
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS07170
gene id: 135719:SAMIE_RS07170
uniprot id: A0A494W351
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

135719:SAMIE RS09150
gene id: 135719:SAMIE_RS09150
uniprot id: A0A494W446
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS07800
gene id: 135719:SAMIE_RS07800
uniprot id: A0A494WBJ1
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

135719:SAMIE RS10050
gene id: 135719:SAMIE_RS10050
uniprot id: A0A494W4N1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS11970
gene id: 135719:SAMIE_RS11970
uniprot id: A0A494W1X4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

135719:SAMIE RS01295
gene id: 135719:SAMIE_RS01295
uniprot id: A0A494W8K0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS19275
gene id: 135719:SAMIE_RS19275
uniprot id: A0A494WG79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

135719:SAMIE RS12955
gene id: 135719:SAMIE_RS12955
uniprot id: A0A494WDJ6
names: Similarity
messages: Belongs to the peptidase M17 family.

135719:SAMIE RS07885
gene id: 135719:SAMIE_RS07885
uniprot id: A0A494W132
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

135719:SAMIE RS04755
gene id: 135719:SAMIE_RS04755
uniprot id: A0A494WAA3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

135719:SAMIE RS03200
gene id: 135719:SAMIE_RS03200
uniprot id: A0A494W9G5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

135719:SAMIE RS07725
gene id: 135719:SAMIE_RS07725
uniprot id: A0A494VZN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

135719:SAMIE RS08010
gene id: 135719:SAMIE_RS08010
uniprot id: A0A494VZT1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

135719:SAMIE RS04640
gene id: 135719:SAMIE_RS04640
uniprot id: A0A494VY59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

135719:SAMIE RS14775
gene id: 135719:SAMIE_RS14775
uniprot id: A0A494WEE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS07735
gene id: 135719:SAMIE_RS07735
uniprot id: A0A494WBH2
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

135719:SAMIE RS20945
gene id: 135719:SAMIE_RS20945
uniprot id: A0A494WGH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

135719:SAMIE RS07745
gene id: 135719:SAMIE_RS07745
uniprot id: A0A494W5N5
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS01615
gene id: 135719:SAMIE_RS01615
uniprot id: A0A494W8N8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

135719:SAMIE RS16145
gene id: 135719:SAMIE_RS16145
uniprot id: A0A494W7R1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

135719:SAMIE RS10085
gene id: 135719:SAMIE_RS10085
uniprot id: A0A494WCH6
names: Similarity
messages: Belongs to the HesB/IscA family.

135719:SAMIE RS12490
gene id: 135719:SAMIE_RS12490
uniprot id: A0A494W818
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS00475
gene id: 135719:SAMIE_RS00475
uniprot id: A0A494W1W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

135719:SAMIE RS07920
gene id: 135719:SAMIE_RS07920
uniprot id: A0A494W5R5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

135719:SAMIE RS05170
gene id: 135719:SAMIE_RS05170
uniprot id: A0A494W275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

135719:SAMIE RS07145
gene id: 135719:SAMIE_RS07145
uniprot id: A0A494W7L6
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

135719:SAMIE RS00150
gene id: 135719:SAMIE_RS00150
uniprot id: A0A494W1R4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

135719:SAMIE RS16795
gene id: 135719:SAMIE_RS16795
uniprot id: A0A494WF97
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

135719:SAMIE RS05360
gene id: 135719:SAMIE_RS05360
uniprot id: A0A494WB39
names: Similarity
messages: Belongs to the Skp family.

135719:SAMIE RS22830
gene id: 135719:SAMIE_RS22830
uniprot id: A0A494W8H3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

135719:SAMIE RS12505
gene id: 135719:SAMIE_RS12505
uniprot id: A0A494WCZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

135719:SAMIE RS14285
gene id: 135719:SAMIE_RS14285
uniprot id: A0A494W343
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

135719:SAMIE RS05105
gene id: 135719:SAMIE_RS05105
uniprot id: A0A494W266
names: Similarity
messages: Belongs to the peptidase S26 family.

135719:SAMIE RS05330
gene id: 135719:SAMIE_RS05330
uniprot id: A0A494VYG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

135719:SAMIE RS18830
gene id: 135719:SAMIE_RS18830
uniprot id: A0A494W5K1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

135719:SAMIE RS05680
gene id: 135719:SAMIE_RS05680
uniprot id: A0A494WAL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

135719:SAMIE RS09520
gene id: 135719:SAMIE_RS09520
uniprot id: A0A494W4B1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

135719:SAMIE RS07945
gene id: 135719:SAMIE_RS07945
uniprot id: A0A494WBJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

135719:SAMIE RS10520
gene id: 135719:SAMIE_RS10520
uniprot id: A0A494W5D1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

135719:SAMIE RS07550
gene id: 135719:SAMIE_RS07550
uniprot id: A0A494WBE5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS18405
gene id: 135719:SAMIE_RS18405
uniprot id: A0A494WGB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

135719:SAMIE RS06590
gene id: 135719:SAMIE_RS06590
uniprot id: A0A494WB00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

135719:SAMIE RS01315
gene id: 135719:SAMIE_RS01315
uniprot id: A0A494W014
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is located at the dimer interface.

135719:SAMIE RS21470
gene id: 135719:SAMIE_RS21470
uniprot id: A0A494W7L6
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

135719:SAMIE RS22945
gene id: 135719:SAMIE_RS22945
uniprot id: A0A494WBR5
names: Similarity
messages: Belongs to the transposase 7 family.

135719:SAMIE RS00245
gene id: 135719:SAMIE_RS00245
uniprot id: A0A494W7Z5
names: Similarity
messages: Belongs to the AlaDH/PNT family.

135719:SAMIE RS23160
gene id: 135719:SAMIE_RS23160
uniprot id: A0A494W7Q1
names: Similarity
messages: Belongs to the transposase 7 family.

135719:SAMIE RS06870
gene id: 135719:SAMIE_RS06870
uniprot id: A0A494VZ70
names: Similarity
messages: Belongs to the MreC family.

135719:SAMIE RS14490
gene id: 135719:SAMIE_RS14490
uniprot id: A0A494WDV4
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS05420
gene id: 135719:SAMIE_RS05420
uniprot id: A0A494W2T8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

135719:SAMIE RS10840
gene id: 135719:SAMIE_RS10840
uniprot id: A0A494WCB7
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.
messages: Binds 1 heme c group per subunit.

135719:SAMIE RS07675
gene id: 135719:SAMIE_RS07675
uniprot id: A0A494WBG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

135719:SAMIE RS12530
gene id: 135719:SAMIE_RS12530
uniprot id: A0A494W262
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

135719:SAMIE RS12415
gene id: 135719:SAMIE_RS12415
uniprot id: A0A494W250
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

135719:SAMIE RS14975
gene id: 135719:SAMIE_RS14975
uniprot id: A0A494W4L4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

135719:SAMIE RS13665
gene id: 135719:SAMIE_RS13665
uniprot id: A0A494WDV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

135719:SAMIE RS17780
gene id: 135719:SAMIE_RS17780
uniprot id: A0A494WG33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

135719:SAMIE RS02210
gene id: 135719:SAMIE_RS02210
uniprot id: A0A494W925
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

135719:SAMIE RS06790
gene id: 135719:SAMIE_RS06790
uniprot id: A0A494WBQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: May be required for disulfide bond formation in some proteins.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

135719:SAMIE RS09205
gene id: 135719:SAMIE_RS09205
uniprot id: A0A494W456
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

135719:SAMIE RS11230
gene id: 135719:SAMIE_RS11230
uniprot id: A0A494W597
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS00810
gene id: 135719:SAMIE_RS00810
uniprot id: A0A494W233
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS11800
gene id: 135719:SAMIE_RS11800
uniprot id: A0A494W5J5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

135719:SAMIE RS18460
gene id: 135719:SAMIE_RS18460
uniprot id: A0A494WAS9
names: Similarity
messages: Belongs to the Dps family.

135719:SAMIE RS18645
gene id: 135719:SAMIE_RS18645
uniprot id: A0A494W6E3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

135719:SAMIE RS07430
gene id: 135719:SAMIE_RS07430
uniprot id: A0A494VZH8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

135719:SAMIE RS11495
gene id: 135719:SAMIE_RS11495
uniprot id: A0A494W1L8
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

135719:SAMIE RS22115
gene id: 135719:SAMIE_RS22115
uniprot id: A0A494WCK0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS17090
gene id: 135719:SAMIE_RS17090
uniprot id: A0A494WF82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS10210
gene id: 135719:SAMIE_RS10210
uniprot id: A0A494W139
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

135719:SAMIE RS04770
gene id: 135719:SAMIE_RS04770
uniprot id: A0A494VY78
names: Similarity
messages: Belongs to the transketolase family.

135719:SAMIE RS11255
gene id: 135719:SAMIE_RS11255
uniprot id: A0A494W2S8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS17525
gene id: 135719:SAMIE_RS17525
uniprot id: A0A494WFD3
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS08290
gene id: 135719:SAMIE_RS08290
uniprot id: A0A494VZX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

135719:SAMIE RS07335
gene id: 135719:SAMIE_RS07335
uniprot id: A0A494W381
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

135719:SAMIE RS13485
gene id: 135719:SAMIE_RS13485
uniprot id: A0A494W6R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

135719:SAMIE RS08160
gene id: 135719:SAMIE_RS08160
uniprot id: A0A494WCC7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

135719:SAMIE RS17765
gene id: 135719:SAMIE_RS17765
uniprot id: A0A494W8K6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

135719:SAMIE RS09445
gene id: 135719:SAMIE_RS09445
uniprot id: A0A494W0Q3
names: Similarity
messages: Belongs to the peptidase C40 family.

135719:SAMIE RS06540
gene id: 135719:SAMIE_RS06540
uniprot id: A0A494VZ21
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS10980
gene id: 135719:SAMIE_RS10980
uniprot id: A0A494W1G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

135719:SAMIE RS01555
gene id: 135719:SAMIE_RS01555
uniprot id: A0A494VWI5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

135719:SAMIE RS05790
gene id: 135719:SAMIE_RS05790
uniprot id: A0A494W4K6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

135719:SAMIE RS21710
gene id: 135719:SAMIE_RS21710
uniprot id: A0A494WHJ0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

135719:SAMIE RS13575
gene id: 135719:SAMIE_RS13575
uniprot id: A0A494W6G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

135719:SAMIE RS19840
gene id: 135719:SAMIE_RS19840
uniprot id: A0A494WA40
names: Similarity
messages: Belongs to the peptidase S9A family.

135719:SAMIE RS07765
gene id: 135719:SAMIE_RS07765
uniprot id: A0A494WAV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

135719:SAMIE RS01940
gene id: 135719:SAMIE_RS01940
uniprot id: A0A494W8T5
names: Similarity
messages: Belongs to the peptidase A24 family.

135719:SAMIE RS14420
gene id: 135719:SAMIE_RS14420
uniprot id: A0A494W6W2
names: Similarity
messages: Belongs to the type IB topoisomerase family.

135719:SAMIE RS18655
gene id: 135719:SAMIE_RS18655
uniprot id: A0A494W5G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

135719:SAMIE RS09245
gene id: 135719:SAMIE_RS09245
uniprot id: A0A494W1R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS16705
gene id: 135719:SAMIE_RS16705
uniprot id: A0A494W8H5
names: Similarity
messages: Belongs to the pirin family.

135719:SAMIE RS13505
gene id: 135719:SAMIE_RS13505
uniprot id: A0A494WDS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

135719:SAMIE RS17870
gene id: 135719:SAMIE_RS17870
uniprot id: A0A494WFN0
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

135719:SAMIE RS07585
gene id: 135719:SAMIE_RS07585
uniprot id: A0A494WAT2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

135719:SAMIE RS02300
gene id: 135719:SAMIE_RS02300
uniprot id: A0A494W9P5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

135719:SAMIE RS02360
gene id: 135719:SAMIE_RS02360
uniprot id: A0A494W8E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS01290
gene id: 135719:SAMIE_RS01290
uniprot id: A0A494VXZ5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

135719:SAMIE RS16205
gene id: 135719:SAMIE_RS16205
uniprot id: A0A494W880
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

135719:SAMIE RS07665
gene id: 135719:SAMIE_RS07665
uniprot id: A0A494VZM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

135719:SAMIE RS20030
gene id: 135719:SAMIE_RS20030
uniprot id: A0A494W748
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

135719:SAMIE RS09535
gene id: 135719:SAMIE_RS09535
uniprot id: A0A494WCY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

135719:SAMIE RS00250
gene id: 135719:SAMIE_RS00250
uniprot id: A0A494VZI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

135719:SAMIE RS02900
gene id: 135719:SAMIE_RS02900
uniprot id: A0A494W329
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

135719:SAMIE RS15980
gene id: 135719:SAMIE_RS15980
uniprot id: A0A494WEX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

135719:SAMIE RS06505
gene id: 135719:SAMIE_RS06505
uniprot id: A0A494W4Y5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

135719:SAMIE RS07150
gene id: 135719:SAMIE_RS07150
uniprot id: A0A494VZ17
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

135719:SAMIE RS00015
gene id: 135719:SAMIE_RS00015
uniprot id: A0A494W7Z3
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS16880
gene id: 135719:SAMIE_RS16880
uniprot id: A0A494WF54
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

135719:SAMIE RS06805
gene id: 135719:SAMIE_RS06805
uniprot id: A0A494WB29
names: Similarity
messages: Belongs to the MobA/MobL family.

135719:SAMIE RS20180
gene id: 135719:SAMIE_RS20180
uniprot id: A0A494WGZ6
names: Function
messages: Acts on leucine, isoleucine and valine.

135719:SAMIE RS09260
gene id: 135719:SAMIE_RS09260
uniprot id: A0A494W0M3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

135719:SAMIE RS12545
gene id: 135719:SAMIE_RS12545
uniprot id: A0A494W5X5
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS16605
gene id: 135719:SAMIE_RS16605
uniprot id: A0A494W8F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

135719:SAMIE RS05570
gene id: 135719:SAMIE_RS05570
uniprot id: A0A494WAJ9
names: Similarity
messages: Belongs to the asparagine synthetase family.

135719:SAMIE RS14070
gene id: 135719:SAMIE_RS14070
uniprot id: A0A494W379
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

135719:SAMIE RS10335
gene id: 135719:SAMIE_RS10335
uniprot id: A0A494W4T3
names: Similarity
messages: Belongs to the GSP E family.

135719:SAMIE RS18695
gene id: 135719:SAMIE_RS18695
uniprot id: A0A494WFL8
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

135719:SAMIE RS03070
gene id: 135719:SAMIE_RS03070
uniprot id: A0A494W8S5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

135719:SAMIE RS19780
gene id: 135719:SAMIE_RS19780
uniprot id: A0A494WGT6
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

135719:SAMIE RS03480
gene id: 135719:SAMIE_RS03480
uniprot id: A0A494VXL6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

135719:SAMIE RS01705
gene id: 135719:SAMIE_RS01705
uniprot id: A0A494W8U4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS14325
gene id: 135719:SAMIE_RS14325
uniprot id: A0A494W4A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

135719:SAMIE RS19530
gene id: 135719:SAMIE_RS19530
uniprot id: A0A494W5Y6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

135719:SAMIE RS22300
gene id: 135719:SAMIE_RS22300
uniprot id: A0A494VZ17
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

135719:SAMIE RS17920
gene id: 135719:SAMIE_RS17920
uniprot id: A0A494W544
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS16725
gene id: 135719:SAMIE_RS16725
uniprot id: A0A494WF32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

135719:SAMIE RS08235
gene id: 135719:SAMIE_RS08235
uniprot id: A0A494VZX3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

135719:SAMIE RS12330
gene id: 135719:SAMIE_RS12330
uniprot id: A0A494WE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

135719:SAMIE RS22060
gene id: 135719:SAMIE_RS22060
uniprot id: A0A494WAN3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

135719:SAMIE RS17130
gene id: 135719:SAMIE_RS17130
uniprot id: A0A494WF06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

135719:SAMIE RS01890
gene id: 135719:SAMIE_RS01890
uniprot id: A0A494W8S7
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS02335
gene id: 135719:SAMIE_RS02335
uniprot id: A0A494W0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

135719:SAMIE RS04555
gene id: 135719:SAMIE_RS04555
uniprot id: A0A494W2E8
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

135719:SAMIE RS00525
gene id: 135719:SAMIE_RS00525
uniprot id: A0A494VZP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS14170
gene id: 135719:SAMIE_RS14170
uniprot id: A0A494W469
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

135719:SAMIE RS21130
gene id: 135719:SAMIE_RS21130
uniprot id: A0A494WGJ5
names: Similarity
messages: Belongs to the Dps family.

135719:SAMIE RS18930
gene id: 135719:SAMIE_RS18930
uniprot id: A0A494W5M7
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS13965
gene id: 135719:SAMIE_RS13965
uniprot id: A0A494WE16
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

135719:SAMIE RS05625
gene id: 135719:SAMIE_RS05625
uniprot id: A0A494W2F3
names: Similarity
messages: Belongs to the UPF0758 family.

135719:SAMIE RS20930
gene id: 135719:SAMIE_RS20930
uniprot id: A0A494WBZ5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

135719:SAMIE RS14535
gene id: 135719:SAMIE_RS14535
uniprot id: A0A494WEX1
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS15600
gene id: 135719:SAMIE_RS15600
uniprot id: A0A494W4Y6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

135719:SAMIE RS19880
gene id: 135719:SAMIE_RS19880
uniprot id: A0A494W9N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

135719:SAMIE RS23070
gene id: 135719:SAMIE_RS23070
uniprot id: A0A494WHA0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

135719:SAMIE RS18310
gene id: 135719:SAMIE_RS18310
uniprot id: A0A494WFF9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

135719:SAMIE RS16005
gene id: 135719:SAMIE_RS16005
uniprot id: A0A494WEI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

135719:SAMIE RS03675
gene id: 135719:SAMIE_RS03675
uniprot id: A0A494W3H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

135719:SAMIE RS07880
gene id: 135719:SAMIE_RS07880
uniprot id: A0A494WAX4
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

135719:SAMIE RS02445
gene id: 135719:SAMIE_RS02445
uniprot id: A0A494W916
names: Similarity
messages: Belongs to the fabD family.

135719:SAMIE RS17960
gene id: 135719:SAMIE_RS17960
uniprot id: A0A494WFA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

135719:SAMIE RS18230
gene id: 135719:SAMIE_RS18230
uniprot id: A0A494W599
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

135719:SAMIE RS14565
gene id: 135719:SAMIE_RS14565
uniprot id: A0A494WEA4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

135719:SAMIE RS16405
gene id: 135719:SAMIE_RS16405
uniprot id: A0A494W7V2
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

135719:SAMIE RS19690
gene id: 135719:SAMIE_RS19690
uniprot id: A0A494W610
names: Similarity
messages: Belongs to the virb1 family.

135719:SAMIE RS16445
gene id: 135719:SAMIE_RS16445
uniprot id: A0A494W4E6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

135719:SAMIE RS13825
gene id: 135719:SAMIE_RS13825
uniprot id: A0A494W2W0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

135719:SAMIE RS11195
gene id: 135719:SAMIE_RS11195
uniprot id: A0A494WCF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

135719:SAMIE RS07540
gene id: 135719:SAMIE_RS07540
uniprot id: A0A494VZJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

135719:SAMIE RS02030
gene id: 135719:SAMIE_RS02030
uniprot id: A0A494VWS6
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

135719:SAMIE RS11895
gene id: 135719:SAMIE_RS11895
uniprot id: A0A494W1U1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

135719:SAMIE RS11085
gene id: 135719:SAMIE_RS11085
uniprot id: A0A494W2P5
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS11065
gene id: 135719:SAMIE_RS11065
uniprot id: A0A494W5L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS09930
gene id: 135719:SAMIE_RS09930
uniprot id: A0A494W4K2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

135719:SAMIE RS02135
gene id: 135719:SAMIE_RS02135
uniprot id: A0A494W8B1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

135719:SAMIE RS16160
gene id: 135719:SAMIE_RS16160
uniprot id: A0A494WFI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

135719:SAMIE RS04815
gene id: 135719:SAMIE_RS04815
uniprot id: A0A494W7L6
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

135719:SAMIE RS05185
gene id: 135719:SAMIE_RS05185
uniprot id: A0A494WB18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

135719:SAMIE RS10240
gene id: 135719:SAMIE_RS10240
uniprot id: A0A494WC18
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS12645
gene id: 135719:SAMIE_RS12645
uniprot id: A0A494W288
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

135719:SAMIE RS07405
gene id: 135719:SAMIE_RS07405
uniprot id: A0A494WAQ7
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

135719:SAMIE RS05255
gene id: 135719:SAMIE_RS05255
uniprot id: A0A494WB25
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS07470
gene id: 135719:SAMIE_RS07470
uniprot id: A0A494WC22
names: Similarity
messages: Belongs to the TrpC family.

135719:SAMIE RS11995
gene id: 135719:SAMIE_RS11995
uniprot id: A0A494WDY3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

135719:SAMIE RS07555
gene id: 135719:SAMIE_RS07555
uniprot id: A0A494W3C6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

135719:SAMIE RS14255
gene id: 135719:SAMIE_RS14255
uniprot id: A0A494W8X0
names: Similarity
messages: Belongs to the histone deacetylase family.

135719:SAMIE RS03025
gene id: 135719:SAMIE_RS03025
uniprot id: A0A494W9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS10260
gene id: 135719:SAMIE_RS10260
uniprot id: A0A494W0Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

135719:SAMIE RS16480
gene id: 135719:SAMIE_RS16480
uniprot id: A0A494W5C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

135719:SAMIE RS01230
gene id: 135719:SAMIE_RS01230
uniprot id: A0A494W8J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

135719:SAMIE RS05400
gene id: 135719:SAMIE_RS05400
uniprot id: A0A494W2B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

135719:SAMIE RS22200
gene id: 135719:SAMIE_RS22200
uniprot id: A0A494WAP9
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.

135719:SAMIE RS01915
gene id: 135719:SAMIE_RS01915
uniprot id: A0A494W886
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS19845
gene id: 135719:SAMIE_RS19845
uniprot id: A0A494WGU5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

135719:SAMIE RS04685
gene id: 135719:SAMIE_RS04685
uniprot id: A0A494VY74
names: Similarity
messages: Belongs to the peptidase U62 family.

135719:SAMIE RS08405
gene id: 135719:SAMIE_RS08405
uniprot id: A0A494VZZ5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

135719:SAMIE RS03535
gene id: 135719:SAMIE_RS03535
uniprot id: A0A494W9N7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

135719:SAMIE RS10820
gene id: 135719:SAMIE_RS10820
uniprot id: A0A494W532
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS03415
gene id: 135719:SAMIE_RS03415
uniprot id: A0A494VZ17
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

135719:SAMIE RS11235
gene id: 135719:SAMIE_RS11235
uniprot id: A0A494W7G0
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS18115
gene id: 135719:SAMIE_RS18115
uniprot id: A0A494W642
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

135719:SAMIE RS15250
gene id: 135719:SAMIE_RS15250
uniprot id: A0A494W3N1
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

135719:SAMIE RS05295
gene id: 135719:SAMIE_RS05295
uniprot id: A0A494W4B8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

135719:SAMIE RS22165
gene id: 135719:SAMIE_RS22165
uniprot id: A0A494W857
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

135719:SAMIE RS08455
gene id: 135719:SAMIE_RS08455
uniprot id: A0A494W004
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

135719:SAMIE RS06460
gene id: 135719:SAMIE_RS06460
uniprot id: A0A494WBK6
names: Similarity
messages: Belongs to the thioredoxin family.

135719:SAMIE RS13670
gene id: 135719:SAMIE_RS13670
uniprot id: A0A494W2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

135719:SAMIE RS02045
gene id: 135719:SAMIE_RS02045
uniprot id: A0A494W0M4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

135719:SAMIE RS00350
gene id: 135719:SAMIE_RS00350
uniprot id: A0A494W815
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

135719:SAMIE RS09175
gene id: 135719:SAMIE_RS09175
uniprot id: A0A494WBI1
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

135719:SAMIE RS07875
gene id: 135719:SAMIE_RS07875
uniprot id: A0A494WC92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

135719:SAMIE RS09145
gene id: 135719:SAMIE_RS09145
uniprot id: A0A494WC78
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.
messages: Binds 1 heme c group per subunit.

135719:SAMIE RS12760
gene id: 135719:SAMIE_RS12760
uniprot id: A0A494W612
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

135719:SAMIE RS00260
gene id: 135719:SAMIE_RS00260
uniprot id: A0A494W078
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

135719:SAMIE RS03990
gene id: 135719:SAMIE_RS03990
uniprot id: A0A494WAH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

135719:SAMIE RS22710
gene id: 135719:SAMIE_RS22710
uniprot id: A0A494WHF7
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS22000
gene id: 135719:SAMIE_RS22000
uniprot id: A0A494WAM8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

135719:SAMIE RS22380
gene id: 135719:SAMIE_RS22380
uniprot id: A0A494WAS8
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

135719:SAMIE RS03985
gene id: 135719:SAMIE_RS03985
uniprot id: A0A494W213
names: Similarity
messages: Belongs to the ABC transporter superfamily.

135719:SAMIE RS18045
gene id: 135719:SAMIE_RS18045
uniprot id: A0A494WAK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

135719:SAMIE RS09335
gene id: 135719:SAMIE_RS09335
uniprot id: A0A494W6G4
names: Similarity
messages: Belongs to the YkuD family.

135719:SAMIE RS01970
gene id: 135719:SAMIE_RS01970
uniprot id: A0A494VYB3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

135719:SAMIE RS12790
gene id: 135719:SAMIE_RS12790
uniprot id: A0A494WDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS07290
gene id: 135719:SAMIE_RS07290
uniprot id: A0A494W3N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

135719:SAMIE RS07780
gene id: 135719:SAMIE_RS07780
uniprot id: A0A494WBG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

135719:SAMIE RS17860
gene id: 135719:SAMIE_RS17860
uniprot id: A0A494W4Z7
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS05285
gene id: 135719:SAMIE_RS05285
uniprot id: A0A494WAF6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

135719:SAMIE RS10525
gene id: 135719:SAMIE_RS10525
uniprot id: A0A494WDC2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

135719:SAMIE RS20250
gene id: 135719:SAMIE_RS20250
uniprot id: A0A494WGE9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

135719:SAMIE RS11225
gene id: 135719:SAMIE_RS11225
uniprot id: A0A494WD06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

135719:SAMIE RS03160
gene id: 135719:SAMIE_RS03160
uniprot id: A0A494W380
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

135719:SAMIE RS07360
gene id: 135719:SAMIE_RS07360
uniprot id: A0A494W0U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

135719:SAMIE RS18325
gene id: 135719:SAMIE_RS18325
uniprot id: A0A494W5A2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

135719:SAMIE RS15840
gene id: 135719:SAMIE_RS15840
uniprot id: A0A494W3Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

135719:SAMIE RS11180
gene id: 135719:SAMIE_RS11180
uniprot id: A0A494W7F0
names: Similarity
messages: Belongs to the GcvT family.

135719:SAMIE RS00990
gene id: 135719:SAMIE_RS00990
uniprot id: A0A494VXW2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

135719:SAMIE RS05550
gene id: 135719:SAMIE_RS05550
uniprot id: A0A494W010
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

135719:SAMIE RS02625
gene id: 135719:SAMIE_RS02625
uniprot id: A0A494VX37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

135719:SAMIE RS08410
gene id: 135719:SAMIE_RS08410
uniprot id: A0A494WBU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

135719:SAMIE RS13490
gene id: 135719:SAMIE_RS13490
uniprot id: A0A494WEI6
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

135719:SAMIE RS07730
gene id: 135719:SAMIE_RS07730
uniprot id: A0A494VZN5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS16870
gene id: 135719:SAMIE_RS16870
uniprot id: A0A494WEX0
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

135719:SAMIE RS07220
gene id: 135719:SAMIE_RS07220
uniprot id: A0A494VZD4
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

135719:SAMIE RS13255
gene id: 135719:SAMIE_RS13255
uniprot id: A0A494WDA7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

135719:SAMIE RS17930
gene id: 135719:SAMIE_RS17930
uniprot id: A0A494W8N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

135719:SAMIE RS09665
gene id: 135719:SAMIE_RS09665
uniprot id: A0A494W0L8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS10020
gene id: 135719:SAMIE_RS10020
uniprot id: A0A494WBX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

135719:SAMIE RS11735
gene id: 135719:SAMIE_RS11735
uniprot id: A0A494W7P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

135719:SAMIE RS04390
gene id: 135719:SAMIE_RS04390
uniprot id: A0A494W3W8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

135719:SAMIE RS15030
gene id: 135719:SAMIE_RS15030
uniprot id: A0A494WEH0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

135719:SAMIE RS14230
gene id: 135719:SAMIE_RS14230
uniprot id: A0A494WE41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

135719:SAMIE RS15910
gene id: 135719:SAMIE_RS15910
uniprot id: A0A494WEW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

135719:SAMIE RS05340
gene id: 135719:SAMIE_RS05340
uniprot id: A0A494WAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

135719:SAMIE RS08200
gene id: 135719:SAMIE_RS08200
uniprot id: A0A494W5W8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

135719:SAMIE RS08150
gene id: 135719:SAMIE_RS08150
uniprot id: A0A494W5W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

135719:SAMIE RS22645
gene id: 135719:SAMIE_RS22645
uniprot id: A0A292GN06
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

135719:SAMIE RS01225
gene id: 135719:SAMIE_RS01225
uniprot id: A0A494VXY3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

135719:SAMIE RS03170
gene id: 135719:SAMIE_RS03170
uniprot id: A0A494WA45
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

135719:SAMIE RS01570
gene id: 135719:SAMIE_RS01570
uniprot id: A0A494W063
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS14705
gene id: 135719:SAMIE_RS14705
uniprot id: A0A494W4G4
names: Similarity
messages: Belongs to the SufE family.

135719:SAMIE RS19150
gene id: 135719:SAMIE_RS19150
uniprot id: A0A494W5R2
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS03205
gene id: 135719:SAMIE_RS03205
uniprot id: A0A494W179
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

135719:SAMIE RS01005
gene id: 135719:SAMIE_RS01005
uniprot id: A0A494VZX1
names: Similarity
messages: Belongs to the HsdR family.

135719:SAMIE RS20925
gene id: 135719:SAMIE_RS20925
uniprot id: A0A494WA56
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

135719:SAMIE RS21620
gene id: 135719:SAMIE_RS21620
uniprot id: A0A494W703
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

135719:SAMIE RS03265
gene id: 135719:SAMIE_RS03265
uniprot id: A0A494W3B0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS02820
gene id: 135719:SAMIE_RS02820
uniprot id: A0A494W9D0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

135719:SAMIE RS10780
gene id: 135719:SAMIE_RS10780
uniprot id: A0A494W5H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

135719:SAMIE RS00610
gene id: 135719:SAMIE_RS00610
uniprot id: A0A494VZ17
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

135719:SAMIE RS11355
gene id: 135719:SAMIE_RS11355
uniprot id: A0A494W5R1
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

135719:SAMIE RS12100
gene id: 135719:SAMIE_RS12100
uniprot id: A0A494W7U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

135719:SAMIE RS17110
gene id: 135719:SAMIE_RS17110
uniprot id: A0A494W892
names: Similarity
messages: Belongs to the PrpF family.

135719:SAMIE RS00690
gene id: 135719:SAMIE_RS00690
uniprot id: A0A494VW53
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

135719:SAMIE RS06410
gene id: 135719:SAMIE_RS06410
uniprot id: A0A494W0E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

135719:SAMIE RS04890
gene id: 135719:SAMIE_RS04890
uniprot id: A0A494WA99
names: Similarity
messages: Belongs to the ABC transporter superfamily.

135719:SAMIE RS07810
gene id: 135719:SAMIE_RS07810
uniprot id: A0A494W5Q0
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

135719:SAMIE RS04635
gene id: 135719:SAMIE_RS04635
uniprot id: A0A494VY69
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

135719:SAMIE RS11875
gene id: 135719:SAMIE_RS11875
uniprot id: A0A494WCQ5
names: Cofactor
messages: Can also use Mn(2+) ion.

135719:SAMIE RS20815
gene id: 135719:SAMIE_RS20815
uniprot id: A0A494WAJ0
names: Similarity
messages: Belongs to the ArsC family.

135719:SAMIE RS07050
gene id: 135719:SAMIE_RS07050
uniprot id: A0A494WB63
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

135719:SAMIE RS19830
gene id: 135719:SAMIE_RS19830
uniprot id: A0A494W9M5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

135719:SAMIE RS20085
gene id: 135719:SAMIE_RS20085
uniprot id: A0A494WG58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

135719:SAMIE RS04510
gene id: 135719:SAMIE_RS04510
uniprot id: A0A494WAR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

135719:SAMIE RS16805
gene id: 135719:SAMIE_RS16805
uniprot id: A0A494WA43
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

135719:SAMIE RS03720
gene id: 135719:SAMIE_RS03720
uniprot id: A0A494W1G7
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

135719:SAMIE RS03710
gene id: 135719:SAMIE_RS03710
uniprot id: A0A494VXQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

135719:SAMIE RS07375
gene id: 135719:SAMIE_RS07375
uniprot id: A0A494VZF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

135719:SAMIE RS21740
gene id: 135719:SAMIE_RS21740
uniprot id: A0A494W734
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

135719:SAMIE RS16905
gene id: 135719:SAMIE_RS16905
uniprot id: A0A494WA60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

135719:SAMIE RS17990
gene id: 135719:SAMIE_RS17990
uniprot id: A0A494W8P0
names: Similarity
messages: Belongs to the peptidase U62 family.

135719:SAMIE RS10750
gene id: 135719:SAMIE_RS10750
uniprot id: A0A494WCR2
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

135719:SAMIE RS07465
gene id: 135719:SAMIE_RS07465
uniprot id: A0A494W3S9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS15670
gene id: 135719:SAMIE_RS15670
uniprot id: A0A494W4Z3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

135719:SAMIE RS02245
gene id: 135719:SAMIE_RS02245
uniprot id: A0A494W9N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

135719:SAMIE RS21960
gene id: 135719:SAMIE_RS21960
uniprot id: A0A494W819
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

135719:SAMIE RS05465
gene id: 135719:SAMIE_RS05465
uniprot id: A0A494WAI4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

135719:SAMIE RS16220
gene id: 135719:SAMIE_RS16220
uniprot id: A0A494W575
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

135719:SAMIE RS18725
gene id: 135719:SAMIE_RS18725
uniprot id: A0A494WG06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

135719:SAMIE RS15545
gene id: 135719:SAMIE_RS15545
uniprot id: A0A494W4X9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

135719:SAMIE RS17530
gene id: 135719:SAMIE_RS17530
uniprot id: A0A494W4T1
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

135719:SAMIE RS14455
gene id: 135719:SAMIE_RS14455
uniprot id: A0A494W374
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

135719:SAMIE RS07775
gene id: 135719:SAMIE_RS07775
uniprot id: A0A494W110
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

135719:SAMIE RS01480
gene id: 135719:SAMIE_RS01480
uniprot id: A0A494W2E0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

135719:SAMIE RS07130
gene id: 135719:SAMIE_RS07130
uniprot id: A0A494WBV9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

135719:SAMIE RS02965
gene id: 135719:SAMIE_RS02965
uniprot id: A0A494W8R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS01605
gene id: 135719:SAMIE_RS01605
uniprot id: A0A494VWJ8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

135719:SAMIE RS11710
gene id: 135719:SAMIE_RS11710
uniprot id: A0A494WD32
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

135719:SAMIE RS21135
gene id: 135719:SAMIE_RS21135
uniprot id: A0A494W7M2
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

135719:SAMIE RS19360
gene id: 135719:SAMIE_RS19360
uniprot id: A0A494W6T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

135719:SAMIE RS11545
gene id: 135719:SAMIE_RS11545
uniprot id: A0A494WD03
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

135719:SAMIE RS04955
gene id: 135719:SAMIE_RS04955
uniprot id: A0A494W2L8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

135719:SAMIE RS02555
gene id: 135719:SAMIE_RS02555
uniprot id: A0A494VX30
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

135719:SAMIE RS10370
gene id: 135719:SAMIE_RS10370
uniprot id: A0A494WCL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS09310
gene id: 135719:SAMIE_RS09310
uniprot id: A0A494WC64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

135719:SAMIE RS17935
gene id: 135719:SAMIE_RS17935
uniprot id: A0A494WAJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

135719:SAMIE RS02290
gene id: 135719:SAMIE_RS02290
uniprot id: A0A494W2S9
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro).

135719:SAMIE RS14000
gene id: 135719:SAMIE_RS14000
uniprot id: A0A494WDZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

135719:SAMIE RS10430
gene id: 135719:SAMIE_RS10430
uniprot id: A0A494W118
names: Similarity
messages: Belongs to the peptidase S9C family.

135719:SAMIE RS00045
gene id: 135719:SAMIE_RS00045
uniprot id: A0A494W1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

135719:SAMIE RS13685
gene id: 135719:SAMIE_RS13685
uniprot id: A0A494W6I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

135719:SAMIE RS22705
gene id: 135719:SAMIE_RS22705
uniprot id: A0A494W7J1
names: Similarity
messages: Belongs to the pirin family.

135719:SAMIE RS12965
gene id: 135719:SAMIE_RS12965
uniprot id: A0A494W2E7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS03085
gene id: 135719:SAMIE_RS03085
uniprot id: A0A494VXD7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

135719:SAMIE RS02845
gene id: 135719:SAMIE_RS02845
uniprot id: A0A494W112
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

135719:SAMIE RS21715
gene id: 135719:SAMIE_RS21715
uniprot id: A0A494WGS3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

135719:SAMIE RS18750
gene id: 135719:SAMIE_RS18750
uniprot id: A0A494WFM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

135719:SAMIE RS04445
gene id: 135719:SAMIE_RS04445
uniprot id: A0A494W3X8
names: Similarity
messages: Belongs to the ros/MucR family.

135719:SAMIE RS16520
gene id: 135719:SAMIE_RS16520
uniprot id: A0A494WFN1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

135719:SAMIE RS01310
gene id: 135719:SAMIE_RS01310
uniprot id: A0A494W8I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

135719:SAMIE RS14210
gene id: 135719:SAMIE_RS14210
uniprot id: A0A494W788
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

135719:SAMIE RS07495
gene id: 135719:SAMIE_RS07495
uniprot id: A0A494VZI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

135719:SAMIE RS22290
gene id: 135719:SAMIE_RS22290
uniprot id: A0A494WGZ7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

135719:SAMIE RS15635
gene id: 135719:SAMIE_RS15635
uniprot id: A0A494W403
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

135719:SAMIE RS19110
gene id: 135719:SAMIE_RS19110
uniprot id: A0A494W999
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

135719:SAMIE RS04575
gene id: 135719:SAMIE_RS04575
uniprot id: A0A494WA80
names: Similarity
messages: Belongs to the TrpF family.

135719:SAMIE RS14135
gene id: 135719:SAMIE_RS14135
uniprot id: A0A494W6Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

135719:SAMIE RS15490
gene id: 135719:SAMIE_RS15490
uniprot id: A0A494W4X3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

135719:SAMIE RS08945
gene id: 135719:SAMIE_RS08945
uniprot id: A0A494WC36
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

135719:SAMIE RS01305
gene id: 135719:SAMIE_RS01305
uniprot id: A0A494VWD5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

135719:SAMIE RS16655
gene id: 135719:SAMIE_RS16655
uniprot id: A0A494W8G1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

135719:SAMIE RS19515
gene id: 135719:SAMIE_RS19515
uniprot id: A0A494W6V9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

135719:SAMIE RS09940
gene id: 135719:SAMIE_RS09940
uniprot id: A0A494W524
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS01900
gene id: 135719:SAMIE_RS01900
uniprot id: A0A494W2L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

135719:SAMIE RS06570
gene id: 135719:SAMIE_RS06570
uniprot id: A0A494W3B1
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

135719:SAMIE RS03470
gene id: 135719:SAMIE_RS03470
uniprot id: A0A494VZ25
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

135719:SAMIE RS07870
gene id: 135719:SAMIE_RS07870
uniprot id: A0A494W401
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

135719:SAMIE RS04950
gene id: 135719:SAMIE_RS04950
uniprot id: A0A494W464
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

135719:SAMIE RS07415
gene id: 135719:SAMIE_RS07415
uniprot id: A0A494WBB6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

135719:SAMIE RS11385
gene id: 135719:SAMIE_RS11385
uniprot id: A0A494W1J0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

135719:SAMIE RS11510
gene id: 135719:SAMIE_RS11510
uniprot id: A0A494WD42
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

135719:SAMIE RS11360
gene id: 135719:SAMIE_RS11360
uniprot id: A0A494WDP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

135719:SAMIE RS14175
gene id: 135719:SAMIE_RS14175
uniprot id: A0A494WE37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

135719:SAMIE RS00205
gene id: 135719:SAMIE_RS00205
uniprot id: A0A494W1S2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

135719:SAMIE RS18505
gene id: 135719:SAMIE_RS18505
uniprot id: A0A494WFX3
names: Similarity
messages: Belongs to the pirin family.

135719:SAMIE RS19800
gene id: 135719:SAMIE_RS19800
uniprot id: A0A494WG88
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS05365
gene id: 135719:SAMIE_RS05365
uniprot id: A0A494W9Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

135719:SAMIE RS14315
gene id: 135719:SAMIE_RS14315
uniprot id: A0A494WEU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

135719:SAMIE RS20210
gene id: 135719:SAMIE_RS20210
uniprot id: A0A494WGJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

135719:SAMIE RS20050
gene id: 135719:SAMIE_RS20050
uniprot id: A0A494W674
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS03670
gene id: 135719:SAMIE_RS03670
uniprot id: A0A494W1F7
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

135719:SAMIE RS06365
gene id: 135719:SAMIE_RS06365
uniprot id: A0A494VYZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

135719:SAMIE RS17915
gene id: 135719:SAMIE_RS17915
uniprot id: A0A494W507
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

135719:SAMIE RS11185
gene id: 135719:SAMIE_RS11185
uniprot id: A0A494W5N8
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

135719:SAMIE RS00835
gene id: 135719:SAMIE_RS00835
uniprot id: A0A494W8E0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

135719:SAMIE RS04545
gene id: 135719:SAMIE_RS04545
uniprot id: A0A494W1W7
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS16465
gene id: 135719:SAMIE_RS16465
uniprot id: A0A494W8C9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

135719:SAMIE RS11470
gene id: 135719:SAMIE_RS11470
uniprot id: A0A494W5T0
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS21950
gene id: 135719:SAMIE_RS21950
uniprot id: A0A494WHM6
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

135719:SAMIE RS08245
gene id: 135719:SAMIE_RS08245
uniprot id: A0A494WBS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

135719:SAMIE RS14215
gene id: 135719:SAMIE_RS14215
uniprot id: A0A494WET0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

135719:SAMIE RS18545
gene id: 135719:SAMIE_RS18545
uniprot id: A0A494W5E3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

135719:SAMIE RS07225
gene id: 135719:SAMIE_RS07225
uniprot id: A0A494WB88
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

135719:SAMIE RS09130
gene id: 135719:SAMIE_RS09130
uniprot id: A0A494WC37
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS14735
gene id: 135719:SAMIE_RS14735
uniprot id: A0A494W954
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

135719:SAMIE RS04380
gene id: 135719:SAMIE_RS04380
uniprot id: A0A494WA21
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

135719:SAMIE RS03040
gene id: 135719:SAMIE_RS03040
uniprot id: A0A494W9E0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS02650
gene id: 135719:SAMIE_RS02650
uniprot id: A0A494W9V8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

135719:SAMIE RS16535
gene id: 135719:SAMIE_RS16535
uniprot id: A0A494W5D4
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS11625
gene id: 135719:SAMIE_RS11625
uniprot id: A0A494W8B9
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

135719:SAMIE RS05795
gene id: 135719:SAMIE_RS05795
uniprot id: A0A494W2Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

135719:SAMIE RS04245
gene id: 135719:SAMIE_RS04245
uniprot id: A0A494W273
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

135719:SAMIE RS21930
gene id: 135719:SAMIE_RS21930
uniprot id: A0A494WAL4
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

135719:SAMIE RS19755
gene id: 135719:SAMIE_RS19755
uniprot id: A0A494WGE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

135719:SAMIE RS04395
gene id: 135719:SAMIE_RS04395
uniprot id: A0A494W2B3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

135719:SAMIE RS02600
gene id: 135719:SAMIE_RS02600
uniprot id: A0A494W8I9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

135719:SAMIE RS10080
gene id: 135719:SAMIE_RS10080
uniprot id: A0A494W277
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

135719:SAMIE RS09185
gene id: 135719:SAMIE_RS09185
uniprot id: A0A494WC53
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

135719:SAMIE RS19715
gene id: 135719:SAMIE_RS19715
uniprot id: A0A494WA26
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

135719:SAMIE RS13510
gene id: 135719:SAMIE_RS13510
uniprot id: A0A494W2P3
names: Subunit
messages: Homodimer.

135719:SAMIE RS06475
gene id: 135719:SAMIE_RS06475
uniprot id: A0A494WAX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

135719:SAMIE RS08155
gene id: 135719:SAMIE_RS08155
uniprot id: A0A494W449
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

135719:SAMIE RS02275
gene id: 135719:SAMIE_RS02275
uniprot id: A0A494VWX6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

135719:SAMIE RS15100
gene id: 135719:SAMIE_RS15100
uniprot id: A0A494W3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS22790
gene id: 135719:SAMIE_RS22790
uniprot id: A0A494WAZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

135719:SAMIE RS21625
gene id: 135719:SAMIE_RS21625
uniprot id: A0A494W715
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

135719:SAMIE RS16770
gene id: 135719:SAMIE_RS16770
uniprot id: A0A494WEV5
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

135719:SAMIE RS10305
gene id: 135719:SAMIE_RS10305
uniprot id: A0A494W2A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

135719:SAMIE RS12435
gene id: 135719:SAMIE_RS12435
uniprot id: A0A494W806
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

135719:SAMIE RS09355
gene id: 135719:SAMIE_RS09355
uniprot id: A0A494W1T8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

135719:SAMIE RS05325
gene id: 135719:SAMIE_RS05325
uniprot id: A0A494WAH9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS07325
gene id: 135719:SAMIE_RS07325
uniprot id: A0A494VZF1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

135719:SAMIE RS02410
gene id: 135719:SAMIE_RS02410
uniprot id: A0A494W163
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

135719:SAMIE RS03680
gene id: 135719:SAMIE_RS03680
uniprot id: A0A494W1V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

135719:SAMIE RS04155
gene id: 135719:SAMIE_RS04155
uniprot id: A0A494VZD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

135719:SAMIE RS09255
gene id: 135719:SAMIE_RS09255
uniprot id: A0A494W0E8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

135719:SAMIE RS03275
gene id: 135719:SAMIE_RS03275
uniprot id: A0A494WA63
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

135719:SAMIE RS07235
gene id: 135719:SAMIE_RS07235
uniprot id: A0A494W5D6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

135719:SAMIE RS13980
gene id: 135719:SAMIE_RS13980
uniprot id: A0A494W707
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

135719:SAMIE RS04150
gene id: 135719:SAMIE_RS04150
uniprot id: A0A494W9B5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

135719:SAMIE RS07625
gene id: 135719:SAMIE_RS07625
uniprot id: A0A494W3V9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

135719:SAMIE RS13455
gene id: 135719:SAMIE_RS13455
uniprot id: A0A494WDR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

135719:SAMIE RS03120
gene id: 135719:SAMIE_RS03120
uniprot id: A0A494WA37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS14150
gene id: 135719:SAMIE_RS14150
uniprot id: A0A494WES7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

135719:SAMIE RS17895
gene id: 135719:SAMIE_RS17895
uniprot id: A0A494WG44
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

135719:SAMIE RS13495
gene id: 135719:SAMIE_RS13495
uniprot id: A0A494WDG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

135719:SAMIE RS13000
gene id: 135719:SAMIE_RS13000
uniprot id: A0A494WD67
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

135719:SAMIE RS03505
gene id: 135719:SAMIE_RS03505
uniprot id: A0A494W3E7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

135719:SAMIE RS02230
gene id: 135719:SAMIE_RS02230
uniprot id: A0A494W0Q2
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

135719:SAMIE RS21475
gene id: 135719:SAMIE_RS21475
uniprot id: A0A494VZ17
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

135719:SAMIE RS08390
gene id: 135719:SAMIE_RS08390
uniprot id: A0A494W1C2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

135719:SAMIE RS00410
gene id: 135719:SAMIE_RS00410
uniprot id: A0A494W825
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

135719:SAMIE RS19475
gene id: 135719:SAMIE_RS19475
uniprot id: A0A494W5X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS09605
gene id: 135719:SAMIE_RS09605
uniprot id: A0A494W1X9
names: Similarity
messages: Belongs to the MlaA family.

135719:SAMIE RS08020
gene id: 135719:SAMIE_RS08020
uniprot id: A0A494WBM9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

135719:SAMIE RS13795
gene id: 135719:SAMIE_RS13795
uniprot id: A0A494W8P2
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

135719:SAMIE RS14020
gene id: 135719:SAMIE_RS14020
uniprot id: A0A494WE20
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

135719:SAMIE RS02015
gene id: 135719:SAMIE_RS02015
uniprot id: A0A494W8A0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

135719:SAMIE RS13460
gene id: 135719:SAMIE_RS13460
uniprot id: A0A494W2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS11975
gene id: 135719:SAMIE_RS11975
uniprot id: A0A494WD90
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.

135719:SAMIE RS21970
gene id: 135719:SAMIE_RS21970
uniprot id: A0A494WH31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

135719:SAMIE RS17535
gene id: 135719:SAMIE_RS17535
uniprot id: A0A494W4X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

135719:SAMIE RS14575
gene id: 135719:SAMIE_RS14575
uniprot id: A0A494W930
names: Similarity
messages: Belongs to the glutamate synthase family.

135719:SAMIE RS01645
gene id: 135719:SAMIE_RS01645
uniprot id: A0A494VY66
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

135719:SAMIE RS02880
gene id: 135719:SAMIE_RS02880
uniprot id: A0A494VX89
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

135719:SAMIE RS16370
gene id: 135719:SAMIE_RS16370
uniprot id: A0A494WEQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS02735
gene id: 135719:SAMIE_RS02735
uniprot id: A0A494W985
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS13345
gene id: 135719:SAMIE_RS13345
uniprot id: A0A494WDS1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

135719:SAMIE RS17675
gene id: 135719:SAMIE_RS17675
uniprot id: A0A494W8X8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

135719:SAMIE RS06140
gene id: 135719:SAMIE_RS06140
uniprot id: A0A494W0A9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

135719:SAMIE RS11435
gene id: 135719:SAMIE_RS11435
uniprot id: A0A494W2V5
names: Similarity
messages: Belongs to the TlyA family.

135719:SAMIE RS00750
gene id: 135719:SAMIE_RS00750
uniprot id: A0A494W891
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

135719:SAMIE RS14040
gene id: 135719:SAMIE_RS14040
uniprot id: A0A494W716
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

135719:SAMIE RS17830
gene id: 135719:SAMIE_RS17830
uniprot id: A0A494VZ17
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

135719:SAMIE RS07860
gene id: 135719:SAMIE_RS07860
uniprot id: A0A494W3I7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS00330
gene id: 135719:SAMIE_RS00330
uniprot id: A0A494VXL0
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

135719:SAMIE RS20105
gene id: 135719:SAMIE_RS20105
uniprot id: A0A494W684
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

135719:SAMIE RS18130
gene id: 135719:SAMIE_RS18130
uniprot id: A0A494W582
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

135719:SAMIE RS18730
gene id: 135719:SAMIE_RS18730
uniprot id: A0A494W931
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

135719:SAMIE RS12230
gene id: 135719:SAMIE_RS12230
uniprot id: A0A494W375
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

135719:SAMIE RS07475
gene id: 135719:SAMIE_RS07475
uniprot id: A0A494WAR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

135719:SAMIE RS15565
gene id: 135719:SAMIE_RS15565
uniprot id: A0A494W3Y9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

135719:SAMIE RS13065
gene id: 135719:SAMIE_RS13065
uniprot id: A0A494WDL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

135719:SAMIE RS14835
gene id: 135719:SAMIE_RS14835
uniprot id: A0A494W3L6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

135719:SAMIE RS14860
gene id: 135719:SAMIE_RS14860
uniprot id: A0A494WF15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS13925
gene id: 135719:SAMIE_RS13925
uniprot id: A0A494W8R3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS05180
gene id: 135719:SAMIE_RS05180
uniprot id: A0A494W2Q3
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

135719:SAMIE RS20055
gene id: 135719:SAMIE_RS20055
uniprot id: A0A494WGH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

135719:SAMIE RS01240
gene id: 135719:SAMIE_RS01240
uniprot id: A0A494VWD1
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

135719:SAMIE RS06945
gene id: 135719:SAMIE_RS06945
uniprot id: A0A494W3I6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

135719:SAMIE RS15460
gene id: 135719:SAMIE_RS15460
uniprot id: A0A494W7X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS15335
gene id: 135719:SAMIE_RS15335
uniprot id: A0A494W7V4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

135719:SAMIE RS19940
gene id: 135719:SAMIE_RS19940
uniprot id: A0A494W9P7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

135719:SAMIE RS03525
gene id: 135719:SAMIE_RS03525
uniprot id: A0A494W902
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

135719:SAMIE RS18785
gene id: 135719:SAMIE_RS18785
uniprot id: A0A494W942
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS02035
gene id: 135719:SAMIE_RS02035
uniprot id: A0A494VWT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

135719:SAMIE RS10390
gene id: 135719:SAMIE_RS10390
uniprot id: A0A494W4U3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

135719:SAMIE RS17505
gene id: 135719:SAMIE_RS17505
uniprot id: A0A494WFZ8
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

135719:SAMIE RS15765
gene id: 135719:SAMIE_RS15765
uniprot id: A0A494W823
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

135719:SAMIE RS15665
gene id: 135719:SAMIE_RS15665
uniprot id: A0A494WEE4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

135719:SAMIE RS20065
gene id: 135719:SAMIE_RS20065
uniprot id: A0A494WBK0
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS00395
gene id: 135719:SAMIE_RS00395
uniprot id: A0A494W863
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

135719:SAMIE RS04940
gene id: 135719:SAMIE_RS04940
uniprot id: A0A494WAA6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

135719:SAMIE RS06395
gene id: 135719:SAMIE_RS06395
uniprot id: A0A494WBJ6
names: Similarity
messages: Belongs to the Dps family.

135719:SAMIE RS12295
gene id: 135719:SAMIE_RS12295
uniprot id: A0A494W221
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

135719:SAMIE RS19960
gene id: 135719:SAMIE_RS19960
uniprot id: A0A494WA54
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS04180
gene id: 135719:SAMIE_RS04180
uniprot id: A0A494W9Y7
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

135719:SAMIE RS15005
gene id: 135719:SAMIE_RS15005
uniprot id: A0A494W996
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

135719:SAMIE RS12990
gene id: 135719:SAMIE_RS12990
uniprot id: A0A494W6J3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

135719:SAMIE RS01685
gene id: 135719:SAMIE_RS01685
uniprot id: A0A494W9C8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS13050
gene id: 135719:SAMIE_RS13050
uniprot id: A0A494WED6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

135719:SAMIE RS14675
gene id: 135719:SAMIE_RS14675
uniprot id: A0A494WEC3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

135719:SAMIE RS03380
gene id: 135719:SAMIE_RS03380
uniprot id: A0A494VXI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

135719:SAMIE RS08365
gene id: 135719:SAMIE_RS08365
uniprot id: A0A494W609
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS16045
gene id: 135719:SAMIE_RS16045
uniprot id: A0A494W9Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

135719:SAMIE RS09655
gene id: 135719:SAMIE_RS09655
uniprot id: A0A494W1Y9
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

135719:SAMIE RS02160
gene id: 135719:SAMIE_RS02160
uniprot id: A0A494VWW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

135719:SAMIE RS16350
gene id: 135719:SAMIE_RS16350
uniprot id: A0A494W7U6
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

135719:SAMIE RS13650
gene id: 135719:SAMIE_RS13650
uniprot id: A0A494WEL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

135719:SAMIE RS04025
gene id: 135719:SAMIE_RS04025
uniprot id: A0A494W1L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS18975
gene id: 135719:SAMIE_RS18975
uniprot id: A0A494W5M5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

135719:SAMIE RS20910
gene id: 135719:SAMIE_RS20910
uniprot id: A0A494WBR5
names: Similarity
messages: Belongs to the transposase 7 family.

135719:SAMIE RS01330
gene id: 135719:SAMIE_RS01330
uniprot id: A0A494W955
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

135719:SAMIE RS14510
gene id: 135719:SAMIE_RS14510
uniprot id: A0A494W3G0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

135719:SAMIE RS17790
gene id: 135719:SAMIE_RS17790
uniprot id: A0A494W5Y7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

135719:SAMIE RS10120
gene id: 135719:SAMIE_RS10120
uniprot id: A0A494W6T4
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS08425
gene id: 135719:SAMIE_RS08425
uniprot id: A0A494W4A2
names: Similarity
messages: Belongs to the Gfa family.

135719:SAMIE RS18620
gene id: 135719:SAMIE_RS18620
uniprot id: A0A494W910
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

135719:SAMIE RS00780
gene id: 135719:SAMIE_RS00780
uniprot id: A0A494VXT2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

135719:SAMIE RS05135
gene id: 135719:SAMIE_RS05135
uniprot id: A0A494VZU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

135719:SAMIE RS20045
gene id: 135719:SAMIE_RS20045
uniprot id: A0A494W669
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

135719:SAMIE RS00050
gene id: 135719:SAMIE_RS00050
uniprot id: A0A494W046
names: Similarity
messages: Belongs to the Tim44 family.

135719:SAMIE RS17735
gene id: 135719:SAMIE_RS17735
uniprot id: A0A494WF79
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

135719:SAMIE RS04080
gene id: 135719:SAMIE_RS04080
uniprot id: A0A494W3P9
names: Similarity
messages: Belongs to the DSD1 family.

135719:SAMIE RS08975
gene id: 135719:SAMIE_RS08975
uniprot id: A0A494W1L6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

135719:SAMIE RS14845
gene id: 135719:SAMIE_RS14845
uniprot id: A0A494W744
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

135719:SAMIE RS16685
gene id: 135719:SAMIE_RS16685
uniprot id: A0A494W4J0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

135719:SAMIE RS01955
gene id: 135719:SAMIE_RS01955
uniprot id: A0A494W0Z3
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS22810
gene id: 135719:SAMIE_RS22810
uniprot id: A0A494WBH0
names: Similarity
messages: Belongs to the MobA/MobL family.

135719:SAMIE RS01675
gene id: 135719:SAMIE_RS01675
uniprot id: A0A494W2I3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M81 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC).

135719:SAMIE RS11725
gene id: 135719:SAMIE_RS11725
uniprot id: A0A494WD61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

135719:SAMIE RS14520
gene id: 135719:SAMIE_RS14520
uniprot id: A0A494W6X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

135719:SAMIE RS15020
gene id: 135719:SAMIE_RS15020
uniprot id: A0A494WE36
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

135719:SAMIE RS08450
gene id: 135719:SAMIE_RS08450
uniprot id: A0A494W011
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

135719:SAMIE RS14085
gene id: 135719:SAMIE_RS14085
uniprot id: A0A494W8T9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

135719:SAMIE RS14800
gene id: 135719:SAMIE_RS14800
uniprot id: A0A494WF09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

135719:SAMIE RS04430
gene id: 135719:SAMIE_RS04430
uniprot id: A0A494VY31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

135719:SAMIE RS18665
gene id: 135719:SAMIE_RS18665
uniprot id: A0A494WFZ7
names: Similarity
messages: Belongs to the threonine synthase family.

135719:SAMIE RS05395
gene id: 135719:SAMIE_RS05395
uniprot id: A0A494WAH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

135719:SAMIE RS19855
gene id: 135719:SAMIE_RS19855
uniprot id: A0A494W723
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

135719:SAMIE RS23950
gene id: 135719:SAMIE_RS23950
uniprot id: A0A494W0S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS12850
gene id: 135719:SAMIE_RS12850
uniprot id: A0A494W2C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

135719:SAMIE RS16710
gene id: 135719:SAMIE_RS16710
uniprot id: A0A494WFQ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS15115
gene id: 135719:SAMIE_RS15115
uniprot id: A0A494W778
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS09325
gene id: 135719:SAMIE_RS09325
uniprot id: A0A494WCB2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

135719:SAMIE RS22575
gene id: 135719:SAMIE_RS22575
uniprot id: A0A494WH33
names: Function
messages: Involved in the transposition of the insertion sequence.

135719:SAMIE RS06290
gene id: 135719:SAMIE_RS06290
uniprot id: A0A494WBH6
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS14760
gene id: 135719:SAMIE_RS14760
uniprot id: A0A494WEC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

135719:SAMIE RS03035
gene id: 135719:SAMIE_RS03035
uniprot id: A0A494VXB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

135719:SAMIE RS05265
gene id: 135719:SAMIE_RS05265
uniprot id: A0A494VZV8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

135719:SAMIE RS14320
gene id: 135719:SAMIE_RS14320
uniprot id: A0A494WDT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

135719:SAMIE RS13205
gene id: 135719:SAMIE_RS13205
uniprot id: A0A494W3N6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

135719:SAMIE RS10225
gene id: 135719:SAMIE_RS10225
uniprot id: A0A494W6V2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

135719:SAMIE RS06455
gene id: 135719:SAMIE_RS06455
uniprot id: A0A494W397
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

135719:SAMIE RS11430
gene id: 135719:SAMIE_RS11430
uniprot id: A0A494WCI6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

135719:SAMIE RS09880
gene id: 135719:SAMIE_RS09880
uniprot id: A0A494W6Q1
names: Similarity
messages: Belongs to the MobA/MobL family.

135719:SAMIE RS15595
gene id: 135719:SAMIE_RS15595
uniprot id: A0A494WEC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

135719:SAMIE RS02005
gene id: 135719:SAMIE_RS02005
uniprot id: A0A494W105
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

135719:SAMIE RS11475
gene id: 135719:SAMIE_RS11475
uniprot id: A0A494WDQ7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

135719:SAMIE RS05720
gene id: 135719:SAMIE_RS05720
uniprot id: A0A494VYN7
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS20190
gene id: 135719:SAMIE_RS20190
uniprot id: A0A494W767
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

135719:SAMIE RS15985
gene id: 135719:SAMIE_RS15985
uniprot id: A0A494W7N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

135719:SAMIE RS22650
gene id: 135719:SAMIE_RS22650
uniprot id: A0A292GNB8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

135719:SAMIE RS07910
gene id: 135719:SAMIE_RS07910
uniprot id: A0A494W3J5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

135719:SAMIE RS09630
gene id: 135719:SAMIE_RS09630
uniprot id: A0A494W4D5
names: Similarity
messages: Belongs to the FGGY kinase family.

135719:SAMIE RS14195
gene id: 135719:SAMIE_RS14195
uniprot id: A0A494WE38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

135719:SAMIE RS12740
gene id: 135719:SAMIE_RS12740
uniprot id: A0A494WDG7
names: Subcellular Location Annotation
messages: Cytoplasm

135719:SAMIE RS03385
gene id: 135719:SAMIE_RS03385
uniprot id: A0A494W9J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

135719:SAMIE RS06655
gene id: 135719:SAMIE_RS06655
uniprot id: A0A494VZ31
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS11565
gene id: 135719:SAMIE_RS11565
uniprot id: A0A494W5F1
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS22585
gene id: 135719:SAMIE_RS22585
uniprot id: A0A494W5Z7
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

135719:SAMIE RS17750
gene id: 135719:SAMIE_RS17750
uniprot id: A0A494W4W7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

135719:SAMIE RS04960
gene id: 135719:SAMIE_RS04960
uniprot id: A0A494WAY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

135719:SAMIE RS03550
gene id: 135719:SAMIE_RS03550
uniprot id: A0A494W9M4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

135719:SAMIE RS05500
gene id: 135719:SAMIE_RS05500
uniprot id: A0A494WAK3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

135719:SAMIE RS13730
gene id: 135719:SAMIE_RS13730
uniprot id: A0A494W304
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

135719:SAMIE RS20185
gene id: 135719:SAMIE_RS20185
uniprot id: A0A494WG74
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

135719:SAMIE RS03185
gene id: 135719:SAMIE_RS03185
uniprot id: A0A494W9I9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

135719:SAMIE RS10815
gene id: 135719:SAMIE_RS10815
uniprot id: A0A494WCW3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS04420
gene id: 135719:SAMIE_RS04420
uniprot id: A0A494WA57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

135719:SAMIE RS02990
gene id: 135719:SAMIE_RS02990
uniprot id: A0A494W9D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

135719:SAMIE RS16280
gene id: 135719:SAMIE_RS16280
uniprot id: A0A494W465
names: Similarity
messages: Belongs to the UPF0260 family.

135719:SAMIE RS11340
gene id: 135719:SAMIE_RS11340
uniprot id: A0A494WD20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

135719:SAMIE RS21725
gene id: 135719:SAMIE_RS21725
uniprot id: A0A494WGZ8
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS16490
gene id: 135719:SAMIE_RS16490
uniprot id: A0A494W4A0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

135719:SAMIE RS16650
gene id: 135719:SAMIE_RS16650
uniprot id: A0A494WA12
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

135719:SAMIE RS04595
gene id: 135719:SAMIE_RS04595
uniprot id: A0A494W1X5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

135719:SAMIE RS18555
gene id: 135719:SAMIE_RS18555
uniprot id: A0A494W5F5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

135719:SAMIE RS07070
gene id: 135719:SAMIE_RS07070
uniprot id: A0A494WBV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

135719:SAMIE RS20200
gene id: 135719:SAMIE_RS20200
uniprot id: A0A494W697
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

135719:SAMIE RS01630
gene id: 135719:SAMIE_RS01630
uniprot id: A0A494W0T2
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS18120
gene id: 135719:SAMIE_RS18120
uniprot id: A0A494WFL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

135719:SAMIE RS05160
gene id: 135719:SAMIE_RS05160
uniprot id: A0A494VYD5
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

135719:SAMIE RS05315
gene id: 135719:SAMIE_RS05315
uniprot id: A0A494W9X6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

135719:SAMIE RS20230
gene id: 135719:SAMIE_RS20230
uniprot id: A0A494WH04
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS03910
gene id: 135719:SAMIE_RS03910
uniprot id: A0A494W9T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

135719:SAMIE RS10655
gene id: 135719:SAMIE_RS10655
uniprot id: A0A494W164
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

135719:SAMIE RS22045
gene id: 135719:SAMIE_RS22045
uniprot id: A0A494W770
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Periplasm

135719:SAMIE RS05450
gene id: 135719:SAMIE_RS05450
uniprot id: A0A494VYI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

135719:SAMIE RS15590
gene id: 135719:SAMIE_RS15590
uniprot id: A0A494WFA8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

135719:SAMIE RS05825
gene id: 135719:SAMIE_RS05825
uniprot id: A0A494VYQ5
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

135719:SAMIE RS16630
gene id: 135719:SAMIE_RS16630
uniprot id: A0A494W4C5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

135719:SAMIE RS04375
gene id: 135719:SAMIE_RS04375
uniprot id: A0A494VY21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

135719:SAMIE RS20475
gene id: 135719:SAMIE_RS20475
uniprot id: A0A494WBR5
names: Similarity
messages: Belongs to the transposase 7 family.

135719:SAMIE RS07030
gene id: 135719:SAMIE_RS07030
uniprot id: A0A494VZA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS11305
gene id: 135719:SAMIE_RS11305
uniprot id: A0A494WDN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

135719:SAMIE RS14145
gene id: 135719:SAMIE_RS14145
uniprot id: A0A494W731
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

135719:SAMIE RS18690
gene id: 135719:SAMIE_RS18690
uniprot id: A0A494WGE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS04280
gene id: 135719:SAMIE_RS04280
uniprot id: A0A494WA02
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

135719:SAMIE RS17635
gene id: 135719:SAMIE_RS17635
uniprot id: A0A494WFE7
names: Similarity
messages: Belongs to the peptidase M24B family.

135719:SAMIE RS07410
gene id: 135719:SAMIE_RS07410
uniprot id: A0A494W0V5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

135719:SAMIE RS17480
gene id: 135719:SAMIE_RS17480
uniprot id: A0A494WFI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

135719:SAMIE RS09340
gene id: 135719:SAMIE_RS09340
uniprot id: A0A494W4R2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS19480
gene id: 135719:SAMIE_RS19480
uniprot id: A0A494W5W5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

135719:SAMIE RS08215
gene id: 135719:SAMIE_RS08215
uniprot id: A0A494WCD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

135719:SAMIE RS20980
gene id: 135719:SAMIE_RS20980
uniprot id: A0A494WC03
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

135719:SAMIE RS08040
gene id: 135719:SAMIE_RS08040
uniprot id: A0A494WCB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

135719:SAMIE RS14065
gene id: 135719:SAMIE_RS14065
uniprot id: A0A494W305
names: Similarity
messages: Belongs to the YciI family.

135719:SAMIE RS09250
gene id: 135719:SAMIE_RS09250
uniprot id: A0A494WC59
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

135719:SAMIE RS02370
gene id: 135719:SAMIE_RS02370
uniprot id: A0A494W957
names: Function
messages: Multidrug efflux pump.

135719:SAMIE RS20225
gene id: 135719:SAMIE_RS20225
uniprot id: A0A494WA96
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

135719:SAMIE RS00380
gene id: 135719:SAMIE_RS00380
uniprot id: A0A494W8S9
names: Function
messages: Acts on leucine, isoleucine and valine.

135719:SAMIE RS19795
gene id: 135719:SAMIE_RS19795
uniprot id: A0A494W718
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

135719:SAMIE RS20505
gene id: 135719:SAMIE_RS20505
uniprot id: A0A494W7A9
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

135719:SAMIE RS10230
gene id: 135719:SAMIE_RS10230
uniprot id: A0A494W577
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

135719:SAMIE RS22395
gene id: 135719:SAMIE_RS22395
uniprot id: A0A494WH11
names: Similarity
messages: Belongs to the ros/MucR family.

135719:SAMIE RS03055
gene id: 135719:SAMIE_RS03055
uniprot id: A0A494W1H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

135719:SAMIE RS15660
gene id: 135719:SAMIE_RS15660
uniprot id: A0A494WFB8
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

135719:SAMIE RS12140
gene id: 135719:SAMIE_RS12140
uniprot id: A0A494WDB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

135719:SAMIE RS15585
gene id: 135719:SAMIE_RS15585
uniprot id: A0A494W7Z4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

135719:SAMIE RS14125
gene id: 135719:SAMIE_RS14125
uniprot id: A0A494W390
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

135719:SAMIE RS11600
gene id: 135719:SAMIE_RS11600
uniprot id: A0A494WD09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

135719:SAMIE RS04370
gene id: 135719:SAMIE_RS04370
uniprot id: A0A494VY19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

135719:SAMIE RS02465
gene id: 135719:SAMIE_RS02465
uniprot id: A0A494W174
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

135719:SAMIE RS18395
gene id: 135719:SAMIE_RS18395
uniprot id: A0A494WAS1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

135719:SAMIE RS05530
gene id: 135719:SAMIE_RS05530
uniprot id: A0A494W4F9
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS05595
gene id: 135719:SAMIE_RS05595
uniprot id: A0A494WA22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

135719:SAMIE RS06965
gene id: 135719:SAMIE_RS06965
uniprot id: A0A494W0N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

135719:SAMIE RS19285
gene id: 135719:SAMIE_RS19285
uniprot id: A0A494WB66
names: Similarity
messages: Belongs to the CFA/CMAS family.

135719:SAMIE RS14200
gene id: 135719:SAMIE_RS14200
uniprot id: A0A494W6R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

135719:SAMIE RS03475
gene id: 135719:SAMIE_RS03475
uniprot id: A0A494W9M7
names: Similarity
messages: Belongs to the bacterial glucokinase family.

135719:SAMIE RS05345
gene id: 135719:SAMIE_RS05345
uniprot id: A0A494W2A4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS11045
gene id: 135719:SAMIE_RS11045
uniprot id: A0A494WCY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

135719:SAMIE RS02285
gene id: 135719:SAMIE_RS02285
uniprot id: A0A494W0R2
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

135719:SAMIE RS18985
gene id: 135719:SAMIE_RS18985
uniprot id: A0A494WG45
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS09625
gene id: 135719:SAMIE_RS09625
uniprot id: A0A494WCF1
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

135719:SAMIE RS09000
gene id: 135719:SAMIE_RS09000
uniprot id: A0A494W416
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

135719:SAMIE RS13615
gene id: 135719:SAMIE_RS13615
uniprot id: A0A494WDU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

135719:SAMIE RS00005
gene id: 135719:SAMIE_RS00005
uniprot id: A0A494W7C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

135719:SAMIE RS16310
gene id: 135719:SAMIE_RS16310
uniprot id: A0A494W896
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

135719:SAMIE RS18660
gene id: 135719:SAMIE_RS18660
uniprot id: A0A494W5H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

135719:SAMIE RS11090
gene id: 135719:SAMIE_RS11090
uniprot id: A0A494WCU7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS16815
gene id: 135719:SAMIE_RS16815
uniprot id: A0A494WFR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS16900
gene id: 135719:SAMIE_RS16900
uniprot id: A0A494W844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS19700
gene id: 135719:SAMIE_RS19700
uniprot id: A0A494WGD3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

135719:SAMIE RS11985
gene id: 135719:SAMIE_RS11985
uniprot id: A0A494W7T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

135719:SAMIE RS15570
gene id: 135719:SAMIE_RS15570
uniprot id: A0A494WER6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

135719:SAMIE RS07315
gene id: 135719:SAMIE_RS07315
uniprot id: A0A494WBA1
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

135719:SAMIE RS18195
gene id: 135719:SAMIE_RS18195
uniprot id: A0A494WAN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

135719:SAMIE RS18760
gene id: 135719:SAMIE_RS18760
uniprot id: A0A494WFU8
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS12290
gene id: 135719:SAMIE_RS12290
uniprot id: A0A494WDB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

135719:SAMIE RS11500
gene id: 135719:SAMIE_RS11500
uniprot id: A0A494W1Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

135719:SAMIE RS18635
gene id: 135719:SAMIE_RS18635
uniprot id: A0A494WGE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

135719:SAMIE RS09015
gene id: 135719:SAMIE_RS09015
uniprot id: A0A494WCR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS15830
gene id: 135719:SAMIE_RS15830
uniprot id: A0A494W514
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

135719:SAMIE RS20525
gene id: 135719:SAMIE_RS20525
uniprot id: A0A494WGM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

135719:SAMIE RS05650
gene id: 135719:SAMIE_RS05650
uniprot id: A0A494WA30
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

135719:SAMIE RS15895
gene id: 135719:SAMIE_RS15895
uniprot id: A0A494WET7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

135719:SAMIE RS21925
gene id: 135719:SAMIE_RS21925
uniprot id: A0A494WH62
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

135719:SAMIE RS01540
gene id: 135719:SAMIE_RS01540
uniprot id: A0A494W808
names: Similarity
messages: Belongs to the glutamine synthetase family.

135719:SAMIE RS13270
gene id: 135719:SAMIE_RS13270
uniprot id: A0A494WDP4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

135719:SAMIE RS20770
gene id: 135719:SAMIE_RS20770
uniprot id: A0A494W6J1
names: Similarity
messages: Belongs to the virb1 family.

135719:SAMIE RS07995
gene id: 135719:SAMIE_RS07995
uniprot id: A0A494W147
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

135719:SAMIE RS03130
gene id: 135719:SAMIE_RS03130
uniprot id: A0A494VYW3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

135719:SAMIE RS13740
gene id: 135719:SAMIE_RS13740
uniprot id: A0A494W6I8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

135719:SAMIE RS04790
gene id: 135719:SAMIE_RS04790
uniprot id: A0A494W2J3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS15865
gene id: 135719:SAMIE_RS15865
uniprot id: A0A494W841
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS16360
gene id: 135719:SAMIE_RS16360
uniprot id: A0A494W8A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

135719:SAMIE RS12400
gene id: 135719:SAMIE_RS12400
uniprot id: A0A494W399
names: Similarity
messages: Belongs to the aspartokinase family.

135719:SAMIE RS17040
gene id: 135719:SAMIE_RS17040
uniprot id: A0A494W4Q6
names: Similarity
messages: Belongs to the UPF0311 family.

135719:SAMIE RS22885
gene id: 135719:SAMIE_RS22885
uniprot id: A0A494W8J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS14130
gene id: 135719:SAMIE_RS14130
uniprot id: A0A494WE33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

135719:SAMIE RS08050
gene id: 135719:SAMIE_RS08050
uniprot id: A0A494W160
names: Similarity
messages: Belongs to the DEAD box helicase family.

135719:SAMIE RS08320
gene id: 135719:SAMIE_RS08320
uniprot id: A0A494WCG0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

135719:SAMIE RS14605
gene id: 135719:SAMIE_RS14605
uniprot id: A0A494WE95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS03640
gene id: 135719:SAMIE_RS03640
uniprot id: A0A494VZ55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

135719:SAMIE RS05820
gene id: 135719:SAMIE_RS05820
uniprot id: A0A494WAP6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

135719:SAMIE RS08180
gene id: 135719:SAMIE_RS08180
uniprot id: A0A494VZW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS12110
gene id: 135719:SAMIE_RS12110
uniprot id: A0A494WDZ7
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS13810
gene id: 135719:SAMIE_RS13810
uniprot id: A0A494VZ17
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

135719:SAMIE RS14225
gene id: 135719:SAMIE_RS14225
uniprot id: A0A494W481
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

135719:SAMIE RS22525
gene id: 135719:SAMIE_RS22525
uniprot id: A0A494W8B9
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

135719:SAMIE RS06955
gene id: 135719:SAMIE_RS06955
uniprot id: A0A494WAK0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

135719:SAMIE RS13765
gene id: 135719:SAMIE_RS13765
uniprot id: A0A494W404
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

135719:SAMIE RS05375
gene id: 135719:SAMIE_RS05375
uniprot id: A0A494WAI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS14440
gene id: 135719:SAMIE_RS14440
uniprot id: A0A494WDU6
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS08145
gene id: 135719:SAMIE_RS08145
uniprot id: A0A494W3M2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

135719:SAMIE RS16930
gene id: 135719:SAMIE_RS16930
uniprot id: A0A494WF62
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS05610
gene id: 135719:SAMIE_RS05610
uniprot id: A0A494VYL7
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

135719:SAMIE RS08965
gene id: 135719:SAMIE_RS08965
uniprot id: A0A494WCR1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

135719:SAMIE RS12305
gene id: 135719:SAMIE_RS12305
uniprot id: A0A494VXW2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

135719:SAMIE RS08140
gene id: 135719:SAMIE_RS08140
uniprot id: A0A494WBQ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

135719:SAMIE RS16325
gene id: 135719:SAMIE_RS16325
uniprot id: A0A494W594
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

135719:SAMIE RS16790
gene id: 135719:SAMIE_RS16790
uniprot id: A0A494W4L3
names: Similarity
messages: Belongs to the HIBADH-related family.

135719:SAMIE RS17835
gene id: 135719:SAMIE_RS17835
uniprot id: A0A494W7L6
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

135719:SAMIE RS22305
gene id: 135719:SAMIE_RS22305
uniprot id: A0A494W7L6
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

135719:SAMIE RS20530
gene id: 135719:SAMIE_RS20530
uniprot id: A0A494W9Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

135719:SAMIE RS22530
gene id: 135719:SAMIE_RS22530
uniprot id: A0A494W7Q1
names: Similarity
messages: Belongs to the transposase 7 family.

135719:SAMIE RS11660
gene id: 135719:SAMIE_RS11660
uniprot id: A0A494WD18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS18895
gene id: 135719:SAMIE_RS18895
uniprot id: A0A494WB01
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS07950
gene id: 135719:SAMIE_RS07950
uniprot id: A0A494VZR6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

135719:SAMIE RS07905
gene id: 135719:SAMIE_RS07905
uniprot id: A0A494WBL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

135719:SAMIE RS19805
gene id: 135719:SAMIE_RS19805
uniprot id: A0A494W627
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

135719:SAMIE RS14155
gene id: 135719:SAMIE_RS14155
uniprot id: A0A494WDR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

135719:SAMIE RS04535
gene id: 135719:SAMIE_RS04535
uniprot id: A0A494VY45
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

135719:SAMIE RS12160
gene id: 135719:SAMIE_RS12160
uniprot id: A0A494W641
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS11705
gene id: 135719:SAMIE_RS11705
uniprot id: A0A494W2Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS07270
gene id: 135719:SAMIE_RS07270
uniprot id: A0A494VZE1
names: Similarity
messages: Belongs to the thioredoxin family.

135719:SAMIE RS05590
gene id: 135719:SAMIE_RS05590
uniprot id: A0A494WB68
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

135719:SAMIE RS16125
gene id: 135719:SAMIE_RS16125
uniprot id: A0A494WEV9
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

135719:SAMIE RS15720
gene id: 135719:SAMIE_RS15720
uniprot id: A0A494WEE8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

135719:SAMIE RS10810
gene id: 135719:SAMIE_RS10810
uniprot id: A0A494W1E1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

135719:SAMIE RS04340
gene id: 135719:SAMIE_RS04340
uniprot id: A0A494W3V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

135719:SAMIE RS19860
gene id: 135719:SAMIE_RS19860
uniprot id: A0A494WG97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

135719:SAMIE RS01640
gene id: 135719:SAMIE_RS01640
uniprot id: A0A494W826
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS06515
gene id: 135719:SAMIE_RS06515
uniprot id: A0A494W3A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

135719:SAMIE RS05025
gene id: 135719:SAMIE_RS05025
uniprot id: A0A494W9T3
names: Similarity
messages: Belongs to the autoinducer synthase family.

135719:SAMIE RS01210
gene id: 135719:SAMIE_RS01210
uniprot id: A0A494W0K7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

135719:SAMIE RS09960
gene id: 135719:SAMIE_RS09960
uniprot id: A0A494WBX7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

135719:SAMIE RS16225
gene id: 135719:SAMIE_RS16225
uniprot id: A0A494WEX3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS16645
gene id: 135719:SAMIE_RS16645
uniprot id: A0A494W7Y9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

135719:SAMIE RS15755
gene id: 135719:SAMIE_RS15755
uniprot id: A0A494W7J4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS05475
gene id: 135719:SAMIE_RS05475
uniprot id: A0A494W4E8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

135719:SAMIE RS16175
gene id: 135719:SAMIE_RS16175
uniprot id: A0A494WEW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

135719:SAMIE RS05815
gene id: 135719:SAMIE_RS05815
uniprot id: A0A494W050
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

135719:SAMIE RS00035
gene id: 135719:SAMIE_RS00035
uniprot id: A0A494VZE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

135719:SAMIE RS09435
gene id: 135719:SAMIE_RS09435
uniprot id: A0A494WC82
names: Similarity
messages: Belongs to the peptidase M17 family.

135719:SAMIE RS16365
gene id: 135719:SAMIE_RS16365
uniprot id: A0A494WFK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

135719:SAMIE RS03925
gene id: 135719:SAMIE_RS03925
uniprot id: A0A494W203
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

135719:SAMIE RS13540
gene id: 135719:SAMIE_RS13540
uniprot id: A0A494WEJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS19340
gene id: 135719:SAMIE_RS19340
uniprot id: A0A494WB75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

135719:SAMIE RS04990
gene id: 135719:SAMIE_RS04990
uniprot id: A0A494VYA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS01035
gene id: 135719:SAMIE_RS01035
uniprot id: A0A494VXW2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

135719:SAMIE RS16295
gene id: 135719:SAMIE_RS16295
uniprot id: A0A494WF27
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

135719:SAMIE RS16840
gene id: 135719:SAMIE_RS16840
uniprot id: A0A494W4L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

135719:SAMIE RS11210
gene id: 135719:SAMIE_RS11210
uniprot id: A0A494W1G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

135719:SAMIE RS17665
gene id: 135719:SAMIE_RS17665
uniprot id: A0A494WAG0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

135719:SAMIE RS05320
gene id: 135719:SAMIE_RS05320
uniprot id: A0A494VZW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

135719:SAMIE RS10205
gene id: 135719:SAMIE_RS10205
uniprot id: A0A494W0Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

135719:SAMIE RS06880
gene id: 135719:SAMIE_RS06880
uniprot id: A0A494WB31
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

135719:SAMIE RS14450
gene id: 135719:SAMIE_RS14450
uniprot id: A0A494WE73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

135719:SAMIE RS22180
gene id: 135719:SAMIE_RS22180
uniprot id: A0A494W790
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

135719:SAMIE RS15860
gene id: 135719:SAMIE_RS15860
uniprot id: A0A494W9N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

135719:SAMIE RS01875
gene id: 135719:SAMIE_RS01875
uniprot id: A0A494W8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

135719:SAMIE RS04360
gene id: 135719:SAMIE_RS04360
uniprot id: A0A494VZG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

135719:SAMIE RS13260
gene id: 135719:SAMIE_RS13260
uniprot id: A0A494W3R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

135719:SAMIE RS19095
gene id: 135719:SAMIE_RS19095
uniprot id: A0A494W5P2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

135719:SAMIE RS10075
gene id: 135719:SAMIE_RS10075
uniprot id: A0A494WBZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

135719:SAMIE RS12635
gene id: 135719:SAMIE_RS12635
uniprot id: A0A494WDF0
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

135719:SAMIE RS07930
gene id: 135719:SAMIE_RS07930
uniprot id: A0A494WCA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

135719:SAMIE RS23120
gene id: 135719:SAMIE_RS23120
uniprot id: A0A494WB47
names: Similarity
messages: Belongs to the RelE toxin family.

135719:SAMIE RS10425
gene id: 135719:SAMIE_RS10425
uniprot id: A0A494WCM1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

135719:SAMIE RS12260
gene id: 135719:SAMIE_RS12260
uniprot id: A0A494W5T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

135719:SAMIE RS18455
gene id: 135719:SAMIE_RS18455
uniprot id: A0A494W8X2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

135719:SAMIE RS05785
gene id: 135719:SAMIE_RS05785
uniprot id: A0A494W2H9
names: Similarity
messages: Belongs to the UPF0262 family.

135719:SAMIE RS10300
gene id: 135719:SAMIE_RS10300
uniprot id: A0A494WC23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

135719:SAMIE RS17190
gene id: 135719:SAMIE_RS17190
uniprot id: A0A494W5P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS05350
gene id: 135719:SAMIE_RS05350
uniprot id: A0A494W4C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

135719:SAMIE RS11515
gene id: 135719:SAMIE_RS11515
uniprot id: A0A494W5E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

135719:SAMIE RS00265
gene id: 135719:SAMIE_RS00265
uniprot id: A0A494W8R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS19850
gene id: 135719:SAMIE_RS19850
uniprot id: A0A494WG30
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

135719:SAMIE RS08955
gene id: 135719:SAMIE_RS08955
uniprot id: A0A494W6A4
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS15410
gene id: 135719:SAMIE_RS15410
uniprot id: A0A494WF93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

135719:SAMIE RS15945
gene id: 135719:SAMIE_RS15945
uniprot id: A0A494W848
names: Similarity
messages: Belongs to the PspA/IM30 family.

135719:SAMIE RS15870
gene id: 135719:SAMIE_RS15870
uniprot id: A0A494WFE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

135719:SAMIE RS06820
gene id: 135719:SAMIE_RS06820
uniprot id: A0A494W2Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS04780
gene id: 135719:SAMIE_RS04780
uniprot id: A0A494W207
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

135719:SAMIE RS13750
gene id: 135719:SAMIE_RS13750
uniprot id: A0A494W6W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

135719:SAMIE RS05730
gene id: 135719:SAMIE_RS05730
uniprot id: A0A494WAL9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS15070
gene id: 135719:SAMIE_RS15070
uniprot id: A0A494W9B1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

135719:SAMIE RS01490
gene id: 135719:SAMIE_RS01490
uniprot id: A0A494W987
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

135719:SAMIE RS12710
gene id: 135719:SAMIE_RS12710
uniprot id: A0A494W602
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

135719:SAMIE RS08375
gene id: 135719:SAMIE_RS08375
uniprot id: A0A494WCH1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS09165
gene id: 135719:SAMIE_RS09165
uniprot id: A0A494WCU4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

135719:SAMIE RS18625
gene id: 135719:SAMIE_RS18625
uniprot id: A0A494WAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

135719:SAMIE RS06225
gene id: 135719:SAMIE_RS06225
uniprot id: A0A494W2Q1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

135719:SAMIE RS16580
gene id: 135719:SAMIE_RS16580
uniprot id: A0A494W4B6
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

135719:SAMIE RS09705
gene id: 135719:SAMIE_RS09705
uniprot id: A0A494W204
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

135719:SAMIE RS22485
gene id: 135719:SAMIE_RS22485
uniprot id: A0A494WBR5
names: Similarity
messages: Belongs to the transposase 7 family.

135719:SAMIE RS09730
gene id: 135719:SAMIE_RS09730
uniprot id: A0A494W4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS05910
gene id: 135719:SAMIE_RS05910
uniprot id: A0A494W316
names: Similarity
messages: Belongs to the ParB family.

135719:SAMIE RS21680
gene id: 135719:SAMIE_RS21680
uniprot id: A0A494W725
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

135719:SAMIE RS09100
gene id: 135719:SAMIE_RS09100
uniprot id: A0A494W435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS11005
gene id: 135719:SAMIE_RS11005
uniprot id: A0A494W5K5
names: Similarity
messages: Belongs to the AlaDH/PNT family.

135719:SAMIE RS16180
gene id: 135719:SAMIE_RS16180
uniprot id: A0A494W441
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS21990
gene id: 135719:SAMIE_RS21990
uniprot id: A0A494W762
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

135719:SAMIE RS04200
gene id: 135719:SAMIE_RS04200
uniprot id: A0A494WAL7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

135719:SAMIE RS18640
gene id: 135719:SAMIE_RS18640
uniprot id: A0A494WFL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

135719:SAMIE RS12995
gene id: 135719:SAMIE_RS12995
uniprot id: A0A494WED1
names: Similarity
messages: Belongs to the OmpW/AlkL family.

135719:SAMIE RS13570
gene id: 135719:SAMIE_RS13570
uniprot id: A0A494WDV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

135719:SAMIE RS06305
gene id: 135719:SAMIE_RS06305
uniprot id: A0A494WAV4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

135719:SAMIE RS11170
gene id: 135719:SAMIE_RS11170
uniprot id: A0A494WCZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

135719:SAMIE RS10250
gene id: 135719:SAMIE_RS10250
uniprot id: A0A494WCJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

135719:SAMIE RS06990
gene id: 135719:SAMIE_RS06990
uniprot id: A0A494W319
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

135719:SAMIE RS13735
gene id: 135719:SAMIE_RS13735
uniprot id: A0A494WDY1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

135719:SAMIE RS14140
gene id: 135719:SAMIE_RS14140
uniprot id: A0A494W8V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

135719:SAMIE RS01865
gene id: 135719:SAMIE_RS01865
uniprot id: A0A494W876
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

135719:SAMIE RS11980
gene id: 135719:SAMIE_RS11980
uniprot id: A0A494W5N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

135719:SAMIE RS11060
gene id: 135719:SAMIE_RS11060
uniprot id: A0A494W7D2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

135719:SAMIE RS12065
gene id: 135719:SAMIE_RS12065
uniprot id: A0A494WCT3
names: Similarity
messages: Belongs to the UPF0102 family.

135719:SAMIE RS06855
gene id: 135719:SAMIE_RS06855
uniprot id: A0A494WAI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

135719:SAMIE RS10025
gene id: 135719:SAMIE_RS10025
uniprot id: A0A494W268
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

135719:SAMIE RS07620
gene id: 135719:SAMIE_RS07620
uniprot id: A0A494W5L8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-55 and Arg-58) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

135719:SAMIE RS10700
gene id: 135719:SAMIE_RS10700
uniprot id: A0A494WCQ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

135719:SAMIE RS04205
gene id: 135719:SAMIE_RS04205
uniprot id: A0A494W9C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

135719:SAMIE RS01930
gene id: 135719:SAMIE_RS01930
uniprot id: A0A494VWQ9
names: Similarity
messages: Belongs to the bacterial secretin family.

135719:SAMIE RS10265
gene id: 135719:SAMIE_RS10265
uniprot id: A0A494W152
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

135719:SAMIE RS12525
gene id: 135719:SAMIE_RS12525
uniprot id: A0A494WDD9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

135719:SAMIE RS04320
gene id: 135719:SAMIE_RS04320
uniprot id: A0A494VY12
names: Similarity
messages: Belongs to the bacterial glucokinase family.

135719:SAMIE RS20150
gene id: 135719:SAMIE_RS20150
uniprot id: A0A494W689
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

135719:SAMIE RS15805
gene id: 135719:SAMIE_RS15805
uniprot id: A0A494W7K1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

135719:SAMIE RS07435
gene id: 135719:SAMIE_RS07435
uniprot id: A0A494WBC9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

135719:SAMIE RS03495
gene id: 135719:SAMIE_RS03495
uniprot id: A0A494W1C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

135719:SAMIE RS06195
gene id: 135719:SAMIE_RS06195
uniprot id: A0A494W0C1
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

135719:SAMIE RS05670
gene id: 135719:SAMIE_RS05670
uniprot id: A0A494VYN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

135719:SAMIE RS13590
gene id: 135719:SAMIE_RS13590
uniprot id: A0A494WEK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

135719:SAMIE RS04230
gene id: 135719:SAMIE_RS04230
uniprot id: A0A494W9Z4
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

135719:SAMIE RS08230
gene id: 135719:SAMIE_RS08230
uniprot id: A0A494WBP5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

135719:SAMIE RS01250
gene id: 135719:SAMIE_RS01250
uniprot id: A0A494W005
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

135719:SAMIE RS10405
gene id: 135719:SAMIE_RS10405
uniprot id: A0A494W5B1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

135719:SAMIE RS11965
gene id: 135719:SAMIE_RS11965
uniprot id: A0A494W1V3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

135719:SAMIE RS07960
gene id: 135719:SAMIE_RS07960
uniprot id: A0A494WBM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

135719:SAMIE RS11245
gene id: 135719:SAMIE_RS11245
uniprot id: A0A494WDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

135719:SAMIE RS12345
gene id: 135719:SAMIE_RS12345
uniprot id: A0A494WDC1
names: Similarity
messages: Belongs to the AHA1 family.

135719:SAMIE RS07535
gene id: 135719:SAMIE_RS07535
uniprot id: A0A494WBD2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

135719:SAMIE RS07890
gene id: 135719:SAMIE_RS07890
uniprot id: A0A494WBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

135719:SAMIE RS07935
gene id: 135719:SAMIE_RS07935
uniprot id: A0A494WAY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

135719:SAMIE RS14515
gene id: 135719:SAMIE_RS14515
uniprot id: A0A494WE93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

135719:SAMIE RS16130
gene id: 135719:SAMIE_RS16130
uniprot id: A0A494W432
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

135719:SAMIE RS04110
gene id: 135719:SAMIE_RS04110
uniprot id: A0A494WA00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

135719:SAMIE RS06905
gene id: 135719:SAMIE_RS06905
uniprot id: A0A494WAJ5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

135719:SAMIE RS04270
gene id: 135719:SAMIE_RS04270
uniprot id: A0A494VY03
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS03515
gene id: 135719:SAMIE_RS03515
uniprot id: A0A494W1R8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

135719:SAMIE RS14090
gene id: 135719:SAMIE_RS14090
uniprot id: A0A494W722
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

135719:SAMIE RS09505
gene id: 135719:SAMIE_RS09505
uniprot id: A0A494W0Q9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

135719:SAMIE RS18965
gene id: 135719:SAMIE_RS18965
uniprot id: A0A494W6L2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

135719:SAMIE RS09910
gene id: 135719:SAMIE_RS09910
uniprot id: A0A494WCG4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

135719:SAMIE RS17940
gene id: 135719:SAMIE_RS17940
uniprot id: A0A494W933
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

135719:SAMIE RS03155
gene id: 135719:SAMIE_RS03155
uniprot id: A0A494W170
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

135719:SAMIE RS16085
gene id: 135719:SAMIE_RS16085
uniprot id: A0A494WEZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

135719:SAMIE RS20270
gene id: 135719:SAMIE_RS20270
uniprot id: A0A494WGJ6
names: Similarity
messages: Belongs to the ParB family.

135719:SAMIE RS05470
gene id: 135719:SAMIE_RS05470
uniprot id: A0A494W2B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

135719:SAMIE RS22600
gene id: 135719:SAMIE_RS22600
uniprot id: A0A292GNB3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

135719:SAMIE RS00195
gene id: 135719:SAMIE_RS00195
uniprot id: A0A494VZH9
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

135719:SAMIE RS17160
gene id: 135719:SAMIE_RS17160
uniprot id: A0A494WFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS11205
gene id: 135719:SAMIE_RS11205
uniprot id: A0A494WCW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

135719:SAMIE RS16500
gene id: 135719:SAMIE_RS16500
uniprot id: A0A494WF58
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

135719:SAMIE RS04355
gene id: 135719:SAMIE_RS04355
uniprot id: A0A494W9G3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

135719:SAMIE RS11120
gene id: 135719:SAMIE_RS11120
uniprot id: A0A494W7E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

135719:SAMIE RS16210
gene id: 135719:SAMIE_RS16210
uniprot id: A0A494WFI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS13780
gene id: 135719:SAMIE_RS13780
uniprot id: A0A494W314
names: Similarity
messages: Belongs to the MotB family.

135719:SAMIE RS08510
gene id: 135719:SAMIE_RS08510
uniprot id: A0A494W016
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS19125
gene id: 135719:SAMIE_RS19125
uniprot id: A0A494WGK4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

135719:SAMIE RS10985
gene id: 135719:SAMIE_RS10985
uniprot id: A0A494WCY2
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

135719:SAMIE RS14840
gene id: 135719:SAMIE_RS14840
uniprot id: A0A494WEF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

135719:SAMIE RS12865
gene id: 135719:SAMIE_RS12865
uniprot id: A0A494WDK3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

135719:SAMIE RS16825
gene id: 135719:SAMIE_RS16825
uniprot id: A0A494W5J0
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

135719:SAMIE RS04490
gene id: 135719:SAMIE_RS04490
uniprot id: A0A494W7V4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

135719:SAMIE RS04560
gene id: 135719:SAMIE_RS04560
uniprot id: A0A494WAR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

135719:SAMIE RS11685
gene id: 135719:SAMIE_RS11685
uniprot id: A0A494W7N0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

135719:SAMIE RS14695
gene id: 135719:SAMIE_RS14695
uniprot id: A0A494WEZ8
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

135719:SAMIE RS10035
gene id: 135719:SAMIE_RS10035
uniprot id: A0A494W0U4
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS09155
gene id: 135719:SAMIE_RS09155
uniprot id: A0A494W6D5
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS04690
gene id: 135719:SAMIE_RS04690
uniprot id: A0A494VY68
names: Similarity
messages: Belongs to the peptidase U62 family.

135719:SAMIE RS13565
gene id: 135719:SAMIE_RS13565
uniprot id: A0A494W2Q4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

135719:SAMIE RS01895
gene id: 135719:SAMIE_RS01895
uniprot id: A0A494W0J0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

135719:SAMIE RS08250
gene id: 135719:SAMIE_RS08250
uniprot id: A0A494W3P6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS19320
gene id: 135719:SAMIE_RS19320
uniprot id: A0A494W5U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

135719:SAMIE RS15475
gene id: 135719:SAMIE_RS15475
uniprot id: A0A494WF98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

135719:SAMIE RS04425
gene id: 135719:SAMIE_RS04425
uniprot id: A0A494VY30
names: Similarity
messages: Belongs to the PhoH family.

135719:SAMIE RS05380
gene id: 135719:SAMIE_RS05380
uniprot id: A0A494VYH2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

135719:SAMIE RS03645
gene id: 135719:SAMIE_RS03645
uniprot id: A0A494W9R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

135719:SAMIE RS12495
gene id: 135719:SAMIE_RS12495
uniprot id: A0A494W6A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS08270
gene id: 135719:SAMIE_RS08270
uniprot id: A0A494WB41
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS18865
gene id: 135719:SAMIE_RS18865
uniprot id: A0A494W6I1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

135719:SAMIE RS00255
gene id: 135719:SAMIE_RS00255
uniprot id: A0A494W1T0
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

135719:SAMIE RS08025
gene id: 135719:SAMIE_RS08025
uniprot id: A0A494W3L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS07340
gene id: 135719:SAMIE_RS07340
uniprot id: A0A494W5F8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

135719:SAMIE RS15650
gene id: 135719:SAMIE_RS15650
uniprot id: A0A494W9K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

135719:SAMIE RS11165
gene id: 135719:SAMIE_RS11165
uniprot id: A0A494W1J9
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

135719:SAMIE RS15955
gene id: 135719:SAMIE_RS15955
uniprot id: A0A494WEI0
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

135719:SAMIE RS07570
gene id: 135719:SAMIE_RS07570
uniprot id: A0A494WC43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

135719:SAMIE RS03995
gene id: 135719:SAMIE_RS03995
uniprot id: A0A494W980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

135719:SAMIE RS06930
gene id: 135719:SAMIE_RS06930
uniprot id: A0A494WB40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

135719:SAMIE RS02400
gene id: 135719:SAMIE_RS02400
uniprot id: A0A494W2U3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

135719:SAMIE RS05685
gene id: 135719:SAMIE_RS05685
uniprot id: A0A494W2G4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

135719:SAMIE RS23165
gene id: 135719:SAMIE_RS23165
uniprot id: A0A494W8B9
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

135719:SAMIE RS18400
gene id: 135719:SAMIE_RS18400
uniprot id: A0A494W9C9
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS12250
gene id: 135719:SAMIE_RS12250
uniprot id: A0A494W223
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

135719:SAMIE RS09360
gene id: 135719:SAMIE_RS09360
uniprot id: A0A494WC73
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS12585
gene id: 135719:SAMIE_RS12585
uniprot id: A0A494W280
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

135719:SAMIE RS00450
gene id: 135719:SAMIE_RS00450
uniprot id: A0A494W872
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

135719:SAMIE RS04715
gene id: 135719:SAMIE_RS04715
uniprot id: A0A494W427
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

135719:SAMIE RS19060
gene id: 135719:SAMIE_RS19060
uniprot id: A0A494W992
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

135719:SAMIE RS20255
gene id: 135719:SAMIE_RS20255
uniprot id: A0A494W6A6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

135719:SAMIE RS01115
gene id: 135719:SAMIE_RS01115
uniprot id: A0A494VZZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

135719:SAMIE RS18570
gene id: 135719:SAMIE_RS18570
uniprot id: A0A494WAU7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

135719:SAMIE RS08370
gene id: 135719:SAMIE_RS08370
uniprot id: A0A494W489
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

135719:SAMIE RS02000
gene id: 135719:SAMIE_RS02000
uniprot id: A0A494W2N7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

135719:SAMIE RS11630
gene id: 135719:SAMIE_RS11630
uniprot id: A0A494W7Q1
names: Similarity
messages: Belongs to the transposase 7 family.

135719:SAMIE RS20960
gene id: 135719:SAMIE_RS20960
uniprot id: A0A494W6M4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

135719:SAMIE RS18900
gene id: 135719:SAMIE_RS18900
uniprot id: A0A494W9M2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS08265
gene id: 135719:SAMIE_RS08265
uniprot id: A0A494WCE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

135719:SAMIE RS12060
gene id: 135719:SAMIE_RS12060
uniprot id: A0A494WDZ2
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

135719:SAMIE RS18140
gene id: 135719:SAMIE_RS18140
uniprot id: A0A494W8R7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

135719:SAMIE RS12085
gene id: 135719:SAMIE_RS12085
uniprot id: A0A494W1Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

135719:SAMIE RS02140
gene id: 135719:SAMIE_RS02140
uniprot id: A0A494VYD9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS16830
gene id: 135719:SAMIE_RS16830
uniprot id: A0A494WF48
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

135719:SAMIE RS14870
gene id: 135719:SAMIE_RS14870
uniprot id: A0A494W4I9
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

135719:SAMIE RS07545
gene id: 135719:SAMIE_RS07545
uniprot id: A0A494VZJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

135719:SAMIE RS18600
gene id: 135719:SAMIE_RS18600
uniprot id: A0A494WFS7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

135719:SAMIE RS12025
gene id: 135719:SAMIE_RS12025
uniprot id: A0A494W1Y2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

135719:SAMIE RS11145
gene id: 135719:SAMIE_RS11145
uniprot id: A0A494WCE7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

135719:SAMIE RS18720
gene id: 135719:SAMIE_RS18720
uniprot id: A0A494W5I2
names: Similarity
messages: Belongs to the virb1 family.

135719:SAMIE RS12005
gene id: 135719:SAMIE_RS12005
uniprot id: A0A494W339
names: Similarity
messages: Belongs to the RNase T2 family.

135719:SAMIE RS00335
gene id: 135719:SAMIE_RS00335
uniprot id: A0A494W855
names: Similarity
messages: Belongs to the LOG family.

135719:SAMIE RS14425
gene id: 135719:SAMIE_RS14425
uniprot id: A0A494W8Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

135719:SAMIE RS09330
gene id: 135719:SAMIE_RS09330
uniprot id: A0A494W474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS13775
gene id: 135719:SAMIE_RS13775
uniprot id: A0A494W2U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

135719:SAMIE RS13935
gene id: 135719:SAMIE_RS13935
uniprot id: A0A494WEP1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

135719:SAMIE RS05520
gene id: 135719:SAMIE_RS05520
uniprot id: A0A494WAJ1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

135719:SAMIE RS01985
gene id: 135719:SAMIE_RS01985
uniprot id: A0A494VWR4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

135719:SAMIE RS21985
gene id: 135719:SAMIE_RS21985
uniprot id: A0A494W766
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

135719:SAMIE RS04035
gene id: 135719:SAMIE_RS04035
uniprot id: A0A494W225
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS11200
gene id: 135719:SAMIE_RS11200
uniprot id: A0A494W2S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

135719:SAMIE RS22150
gene id: 135719:SAMIE_RS22150
uniprot id: A0A494WHR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

135719:SAMIE RS04475
gene id: 135719:SAMIE_RS04475
uniprot id: A0A494VY39
names: Similarity
messages: Belongs to the peptidase M16 family.

135719:SAMIE RS19705
gene id: 135719:SAMIE_RS19705
uniprot id: A0A494W9K4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS04785
gene id: 135719:SAMIE_RS04785
uniprot id: A0A494W438
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

135719:SAMIE RS01360
gene id: 135719:SAMIE_RS01360
uniprot id: A0A494W8J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

135719:SAMIE RS16775
gene id: 135719:SAMIE_RS16775
uniprot id: A0A494W5I3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS13100
gene id: 135719:SAMIE_RS13100
uniprot id: A0A494W6L3
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS12215
gene id: 135719:SAMIE_RS12215
uniprot id: A0A494W650
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

135719:SAMIE RS05110
gene id: 135719:SAMIE_RS05110
uniprot id: A0A494W490
names: Similarity
messages: Belongs to the virb1 family.

135719:SAMIE RS08335
gene id: 135719:SAMIE_RS08335
uniprot id: A0A494WBR0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

135719:SAMIE RS12500
gene id: 135719:SAMIE_RS12500
uniprot id: A0A494WE51
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

135719:SAMIE RS00385
gene id: 135719:SAMIE_RS00385
uniprot id: A0A494W7H9
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

135719:SAMIE RS19835
gene id: 135719:SAMIE_RS19835
uniprot id: A0A494WBG3
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS02020
gene id: 135719:SAMIE_RS02020
uniprot id: A0A494VYC1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

135719:SAMIE RS19495
gene id: 135719:SAMIE_RS19495
uniprot id: A0A494WBA4
names: Similarity
messages: Belongs to the hyi family.

135719:SAMIE RS15655
gene id: 135719:SAMIE_RS15655
uniprot id: A0A494W804
names: Similarity
messages: Belongs to the phosphohexose mutase family.

135719:SAMIE RS07520
gene id: 135719:SAMIE_RS07520
uniprot id: A0A494WC32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

135719:SAMIE RS16700
gene id: 135719:SAMIE_RS16700
uniprot id: A0A494WA25
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

135719:SAMIE RS09485
gene id: 135719:SAMIE_RS09485
uniprot id: A0A494WBN2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

135719:SAMIE RS04440
gene id: 135719:SAMIE_RS04440
uniprot id: A0A494W1U8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

135719:SAMIE RS02130
gene id: 135719:SAMIE_RS02130
uniprot id: A0A494W9M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

135719:SAMIE RS04400
gene id: 135719:SAMIE_RS04400
uniprot id: A0A494WAP7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

135719:SAMIE RS06360
gene id: 135719:SAMIE_RS06360
uniprot id: A0A494WAW3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

135719:SAMIE RS19810
gene id: 135719:SAMIE_RS19810
uniprot id: A0A494W632
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

135719:SAMIE RS02690
gene id: 135719:SAMIE_RS02690
uniprot id: A0A494W2Y7
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

135719:SAMIE RS16970
gene id: 135719:SAMIE_RS16970
uniprot id: A0A494WEY3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

135719:SAMIE RS10785
gene id: 135719:SAMIE_RS10785
uniprot id: A0A494WDG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

135719:SAMIE RS03075
gene id: 135719:SAMIE_RS03075
uniprot id: A0A494VYV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

135719:SAMIE RS06285
gene id: 135719:SAMIE_RS06285
uniprot id: A0A494W369
names: Similarity
messages: Belongs to the universal stress protein A family.

135719:SAMIE RS15715
gene id: 135719:SAMIE_RS15715
uniprot id: A0A494WFC3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS07925
gene id: 135719:SAMIE_RS07925
uniprot id: A0A494W409
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

135719:SAMIE RS03020
gene id: 135719:SAMIE_RS03020
uniprot id: A0A494VYT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

135719:SAMIE RS06465
gene id: 135719:SAMIE_RS06465
uniprot id: A0A494WAD6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

135719:SAMIE RS03920
gene id: 135719:SAMIE_RS03920
uniprot id: A0A494W3M3
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

135719:SAMIE RS10710
gene id: 135719:SAMIE_RS10710
uniprot id: A0A494W1B7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

135719:SAMIE RS16760
gene id: 135719:SAMIE_RS16760
uniprot id: A0A494WFR1
names: Similarity
messages: Belongs to the RelE toxin family.

135719:SAMIE RS14190
gene id: 135719:SAMIE_RS14190
uniprot id: A0A494W3A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

135719:SAMIE RS02455
gene id: 135719:SAMIE_RS02455
uniprot id: A0A494W2V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

135719:SAMIE RS05755
gene id: 135719:SAMIE_RS05755
uniprot id: A0A494WA44
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

135719:SAMIE RS02580
gene id: 135719:SAMIE_RS02580
uniprot id: A0A494W2W6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

135719:SAMIE RS12450
gene id: 135719:SAMIE_RS12450
uniprot id: A0A494WCY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

135719:SAMIE RS04565
gene id: 135719:SAMIE_RS04565
uniprot id: A0A494W9K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

135719:SAMIE RS01910
gene id: 135719:SAMIE_RS01910
uniprot id: A0A494W9G6
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS18055
gene id: 135719:SAMIE_RS18055
uniprot id: A0A494WG71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

135719:SAMIE RS19005
gene id: 135719:SAMIE_RS19005
uniprot id: A0A494WB22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

135719:SAMIE RS00800
gene id: 135719:SAMIE_RS00800
uniprot id: A0A494W899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

135719:SAMIE RS03105
gene id: 135719:SAMIE_RS03105
uniprot id: A0A494W161
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS00615
gene id: 135719:SAMIE_RS00615
uniprot id: A0A494W7L6
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

135719:SAMIE RS07710
gene id: 135719:SAMIE_RS07710
uniprot id: A0A494WAV1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

135719:SAMIE RS06650
gene id: 135719:SAMIE_RS06650
uniprot id: A0A494VZ39
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS22915
gene id: 135719:SAMIE_RS22915
uniprot id: A0A494WHI1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

135719:SAMIE RS04330
gene id: 135719:SAMIE_RS04330
uniprot id: A0A494WA15
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

135719:SAMIE RS07895
gene id: 135719:SAMIE_RS07895
uniprot id: A0A494VZQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

135719:SAMIE RS04325
gene id: 135719:SAMIE_RS04325
uniprot id: A0A494VY06
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

135719:SAMIE RS06915
gene id: 135719:SAMIE_RS06915
uniprot id: A0A494WB43
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

135719:SAMIE RS15835
gene id: 135719:SAMIE_RS15835
uniprot id: A0A494WES8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

135719:SAMIE RS07020
gene id: 135719:SAMIE_RS07020
uniprot id: A0A494WB57
names: Subcellular Location Annotation
messages: Nucleus

135719:SAMIE RS20090
gene id: 135719:SAMIE_RS20090
uniprot id: A0A494W754
names: Similarity
messages: Belongs to the PhzF family.

135719:SAMIE RS20730
gene id: 135719:SAMIE_RS20730
uniprot id: A0A494WGQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

135719:SAMIE RS00155
gene id: 135719:SAMIE_RS00155
uniprot id: A0A494W058
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

135719:SAMIE RS03655
gene id: 135719:SAMIE_RS03655
uniprot id: A0A494VXP1
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS14180
gene id: 135719:SAMIE_RS14180
uniprot id: A0A494W327
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

135719:SAMIE RS00815
gene id: 135719:SAMIE_RS00815
uniprot id: A0A494W0F2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS17925
gene id: 135719:SAMIE_RS17925
uniprot id: A0A494WFN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

135719:SAMIE RS16595
gene id: 135719:SAMIE_RS16595
uniprot id: A0A494W7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS08280
gene id: 135719:SAMIE_RS08280
uniprot id: A0A494W198
names: Similarity
messages: Belongs to the GbsR family.

135719:SAMIE RS00145
gene id: 135719:SAMIE_RS00145
uniprot id: A0A494VZG9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

135719:SAMIE RS14500
gene id: 135719:SAMIE_RS14500
uniprot id: A0A494WE81
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

135719:SAMIE RS08325
gene id: 135719:SAMIE_RS08325
uniprot id: A0A494WB49
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

135719:SAMIE RS21705
gene id: 135719:SAMIE_RS21705
uniprot id: A0A494WAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

135719:SAMIE RS19985
gene id: 135719:SAMIE_RS19985
uniprot id: A0A494WGB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

135719:SAMIE RS11690
gene id: 135719:SAMIE_RS11690
uniprot id: A0A494W5W4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

135719:SAMIE RS16235
gene id: 135719:SAMIE_RS16235
uniprot id: A0A494W4B0
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

135719:SAMIE RS11880
gene id: 135719:SAMIE_RS11880
uniprot id: A0A494W325
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

135719:SAMIE RS00030
gene id: 135719:SAMIE_RS00030
uniprot id: A0A494W7V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

135719:SAMIE RS10640
gene id: 135719:SAMIE_RS10640
uniprot id: A0A494WC83
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS09955
gene id: 135719:SAMIE_RS09955
uniprot id: A0A494WD48
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

135719:SAMIE RS13285
gene id: 135719:SAMIE_RS13285
uniprot id: A0A494W2J6
names: Similarity
messages: Belongs to the UPF0276 family.

135719:SAMIE RS19930
gene id: 135719:SAMIE_RS19930
uniprot id: A0A494W653
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

135719:SAMIE RS06980
gene id: 135719:SAMIE_RS06980
uniprot id: A0A494VZ91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

135719:SAMIE RS16625
gene id: 135719:SAMIE_RS16625
uniprot id: A0A494WF23
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

135719:SAMIE RS05690
gene id: 135719:SAMIE_RS05690
uniprot id: A0A494W4J7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS06950
gene id: 135719:SAMIE_RS06950
uniprot id: A0A494WBT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

135719:SAMIE RS04570
gene id: 135719:SAMIE_RS04570
uniprot id: A0A494VZK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

135719:SAMIE RS00275
gene id: 135719:SAMIE_RS00275
uniprot id: A0A494VXK2
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

135719:SAMIE RS14690
gene id: 135719:SAMIE_RS14690
uniprot id: A0A494W7I2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

135719:SAMIE RS15390
gene id: 135719:SAMIE_RS15390
uniprot id: A0A494W7C8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

135719:SAMIE RS13645
gene id: 135719:SAMIE_RS13645
uniprot id: A0A494W6U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

135719:SAMIE RS02425
gene id: 135719:SAMIE_RS02425
uniprot id: A0A494VYJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

135719:SAMIE RS11865
gene id: 135719:SAMIE_RS11865
uniprot id: A0A494W5Y9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

135719:SAMIE RS02795
gene id: 135719:SAMIE_RS02795
uniprot id: A0A494W1C7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS11420
gene id: 135719:SAMIE_RS11420
uniprot id: A0A494W5S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

135719:SAMIE RS12275
gene id: 135719:SAMIE_RS12275
uniprot id: A0A494WE14
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

135719:SAMIE RS20520
gene id: 135719:SAMIE_RS20520
uniprot id: A0A494W6G1
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

135719:SAMIE RS11795
gene id: 135719:SAMIE_RS11795
uniprot id: A0A494WD66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

135719:SAMIE RS15415
gene id: 135719:SAMIE_RS15415
uniprot id: A0A494WEA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

135719:SAMIE RS00130
gene id: 135719:SAMIE_RS00130
uniprot id: A0A494VVU0
names: Similarity
messages: Belongs to the ArsC family.

135719:SAMIE RS01280
gene id: 135719:SAMIE_RS01280
uniprot id: A0A494W943
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

135719:SAMIE RS11820
gene id: 135719:SAMIE_RS11820
uniprot id: A0A494WCP5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

135719:SAMIE RS18560
gene id: 135719:SAMIE_RS18560
uniprot id: A0A494WFY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

135719:SAMIE RS14625
gene id: 135719:SAMIE_RS14625
uniprot id: A0A494WEB6
names: Subunit
messages: Homotetramer.

135719:SAMIE RS06260
gene id: 135719:SAMIE_RS06260
uniprot id: A0A494VYX1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

135719:SAMIE RS17045
gene id: 135719:SAMIE_RS17045
uniprot id: A0A494WFD7
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS07480
gene id: 135719:SAMIE_RS07480
uniprot id: A0A494W0W4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

135719:SAMIE RS01980
gene id: 135719:SAMIE_RS01980
uniprot id: A0A494VWR8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

135719:SAMIE RS14750
gene id: 135719:SAMIE_RS14750
uniprot id: A0A494WDZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

135719:SAMIE RS14205
gene id: 135719:SAMIE_RS14205
uniprot id: A0A494W8V9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

135719:SAMIE RS22005
gene id: 135719:SAMIE_RS22005
uniprot id: A0A494WCI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

135719:SAMIE RS21685
gene id: 135719:SAMIE_RS21685
uniprot id: A0A494WH34
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

135719:SAMIE RS14720
gene id: 135719:SAMIE_RS14720
uniprot id: A0A494W3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

135719:SAMIE RS07230
gene id: 135719:SAMIE_RS07230
uniprot id: A0A494W363
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

135719:SAMIE RS12405
gene id: 135719:SAMIE_RS12405
uniprot id: A0A494WDC4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

135719:SAMIE RS04775
gene id: 135719:SAMIE_RS04775
uniprot id: A0A494WA72
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

135719:SAMIE RS13610
gene id: 135719:SAMIE_RS13610
uniprot id: A0A494W3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

135719:SAMIE RS04945
gene id: 135719:SAMIE_RS04945
uniprot id: A0A494W238
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

135719:SAMIE RS07980
gene id: 135719:SAMIE_RS07980
uniprot id: A0A494WCA7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

135719:SAMIE RS16660
gene id: 135719:SAMIE_RS16660
uniprot id: A0A494WFP5
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

135719:SAMIE RS07165
gene id: 135719:SAMIE_RS07165
uniprot id: A0A494WB79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

135719:SAMIE RS18840
gene id: 135719:SAMIE_RS18840
uniprot id: A0A494W951
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS22860
gene id: 135719:SAMIE_RS22860
uniprot id: A0A494WB09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS09965
gene id: 135719:SAMIE_RS09965
uniprot id: A0A494W259
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

135719:SAMIE RS16695
gene id: 135719:SAMIE_RS16695
uniprot id: A0A494W7Z6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

135719:SAMIE RS07560
gene id: 135719:SAMIE_RS07560
uniprot id: A0A494W5K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

135719:SAMIE RS18795
gene id: 135719:SAMIE_RS18795
uniprot id: A0A494W9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS15965
gene id: 135719:SAMIE_RS15965
uniprot id: A0A494WEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

135719:SAMIE RS17730
gene id: 135719:SAMIE_RS17730
uniprot id: A0A494WG28
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

135719:SAMIE RS14475
gene id: 135719:SAMIE_RS14475
uniprot id: A0A494W906
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

135719:SAMIE RS02105
gene id: 135719:SAMIE_RS02105
uniprot id: A0A494VWV0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS14540
gene id: 135719:SAMIE_RS14540
uniprot id: A0A494WDW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

135719:SAMIE RS09740
gene id: 135719:SAMIE_RS09740
uniprot id: A0A494W4Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

135719:SAMIE RS12590
gene id: 135719:SAMIE_RS12590
uniprot id: A0A494W279
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

135719:SAMIE RS15170
gene id: 135719:SAMIE_RS15170
uniprot id: A0A494W9D1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

135719:SAMIE RS07090
gene id: 135719:SAMIE_RS07090
uniprot id: A0A494VZA6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

135719:SAMIE RS01420
gene id: 135719:SAMIE_RS01420
uniprot id: A0A494W8K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS17550
gene id: 135719:SAMIE_RS17550
uniprot id: A0A494W8G8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

135719:SAMIE RS15015
gene id: 135719:SAMIE_RS15015
uniprot id: A0A494WF36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

135719:SAMIE RS22580
gene id: 135719:SAMIE_RS22580
uniprot id: A0A494W8C4
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS05705
gene id: 135719:SAMIE_RS05705
uniprot id: A0A494WA36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

135719:SAMIE RS05655
gene id: 135719:SAMIE_RS05655
uniprot id: A0A494W029
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

135719:SAMIE RS18630
gene id: 135719:SAMIE_RS18630
uniprot id: A0A494W9H4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS05725
gene id: 135719:SAMIE_RS05725
uniprot id: A0A494VYN0
names: Similarity
messages: Belongs to the pirin family.

135719:SAMIE RS18685
gene id: 135719:SAMIE_RS18685
uniprot id: A0A494W9I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

135719:SAMIE RS04345
gene id: 135719:SAMIE_RS04345
uniprot id: A0A494W298
names: Similarity
messages: Belongs to the DprA/Smf family.

135719:SAMIE RS03450
gene id: 135719:SAMIE_RS03450
uniprot id: A0A494W3D8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

135719:SAMIE RS14640
gene id: 135719:SAMIE_RS14640
uniprot id: A0A494W7H3
names: Similarity
messages: Belongs to the HesB/IscA family.

135719:SAMIE RS00700
gene id: 135719:SAMIE_RS00700
uniprot id: A0A494VW38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

135719:SAMIE RS10375
gene id: 135719:SAMIE_RS10375
uniprot id: A0A494W109
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

135719:SAMIE RS16475
gene id: 135719:SAMIE_RS16475
uniprot id: A0A494WES3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

135719:SAMIE RS14265
gene id: 135719:SAMIE_RS14265
uniprot id: A0A494WEU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

135719:SAMIE RS05770
gene id: 135719:SAMIE_RS05770
uniprot id: A0A494VYP4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS16720
gene id: 135719:SAMIE_RS16720
uniprot id: A0A494W5H2
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS12515
gene id: 135719:SAMIE_RS12515
uniprot id: A0A494W3B5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

135719:SAMIE RS14530
gene id: 135719:SAMIE_RS14530
uniprot id: A0A494W7F1
names: Similarity
messages: Belongs to the peptidase S41A family.

135719:SAMIE RS14620
gene id: 135719:SAMIE_RS14620
uniprot id: A0A494W3I2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

135719:SAMIE RS13840
gene id: 135719:SAMIE_RS13840
uniprot id: A0A494VXW2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

135719:SAMIE RS14480
gene id: 135719:SAMIE_RS14480
uniprot id: A0A494W7E4
names: Similarity
messages: Belongs to the FBPase class 2 family.

135719:SAMIE RS06865
gene id: 135719:SAMIE_RS06865
uniprot id: A0A494WB37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

135719:SAMIE RS13525
gene id: 135719:SAMIE_RS13525
uniprot id: A0A494W6E5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

135719:SAMIE RS20885
gene id: 135719:SAMIE_RS20885
uniprot id: A0A494WH84
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

135719:SAMIE RS02790
gene id: 135719:SAMIE_RS02790
uniprot id: A0A494W309
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

135719:SAMIE RS10295
gene id: 135719:SAMIE_RS10295
uniprot id: A0A494WD95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

135719:SAMIE RS04365
gene id: 135719:SAMIE_RS04365
uniprot id: A0A494WA49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

135719:SAMIE RS20010
gene id: 135719:SAMIE_RS20010
uniprot id: A0A494WBJ5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

135719:SAMIE RS22295
gene id: 135719:SAMIE_RS22295
uniprot id: A0A494W885
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

135719:SAMIE RS04070
gene id: 135719:SAMIE_RS04070
uniprot id: A0A494W9W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS01355
gene id: 135719:SAMIE_RS01355
uniprot id: A0A494VWE9
names: Similarity
messages: Belongs to the IlvD/Edd family.

135719:SAMIE RS03100
gene id: 135719:SAMIE_RS03100
uniprot id: A0A494W9E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

135719:SAMIE RS11675
gene id: 135719:SAMIE_RS11675
uniprot id: A0A494WD59
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

135719:SAMIE RS05235
gene id: 135719:SAMIE_RS05235
uniprot id: A0A494WAF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

135719:SAMIE RS18910
gene id: 135719:SAMIE_RS18910
uniprot id: A0A494WFQ2
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS12050
gene id: 135719:SAMIE_RS12050
uniprot id: A0A494W7U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

135719:SAMIE RS12410
gene id: 135719:SAMIE_RS12410
uniprot id: A0A494W241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS22735
gene id: 135719:SAMIE_RS22735
uniprot id: A0A494WHY8
names: Similarity
messages: Belongs to the transposase 7 family.

135719:SAMIE RS12745
gene id: 135719:SAMIE_RS12745
uniprot id: A0A494W2A9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

135719:SAMIE RS16140
gene id: 135719:SAMIE_RS16140
uniprot id: A0A494WEZ5
names: Similarity
messages: Belongs to the YkuD family.

135719:SAMIE RS16925
gene id: 135719:SAMIE_RS16925
uniprot id: A0A494W5L0
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS10440
gene id: 135719:SAMIE_RS10440
uniprot id: A0A494WCS2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

135719:SAMIE RS13545
gene id: 135719:SAMIE_RS13545
uniprot id: A0A494WDH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

135719:SAMIE RS14405
gene id: 135719:SAMIE_RS14405
uniprot id: A0A494W362
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

135719:SAMIE RS14660
gene id: 135719:SAMIE_RS14660
uniprot id: A0A494WEA3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

135719:SAMIE RS02450
gene id: 135719:SAMIE_RS02450
uniprot id: A0A494W0U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

135719:SAMIE RS03050
gene id: 135719:SAMIE_RS03050
uniprot id: A0A494W359
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

135719:SAMIE RS03195
gene id: 135719:SAMIE_RS03195
uniprot id: A0A494VXF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

135719:SAMIE RS19295
gene id: 135719:SAMIE_RS19295
uniprot id: A0A494WGM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

135719:SAMIE RS16185
gene id: 135719:SAMIE_RS16185
uniprot id: A0A494W4A5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

135719:SAMIE RS14730
gene id: 135719:SAMIE_RS14730
uniprot id: A0A494W727
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

135719:SAMIE RS11240
gene id: 135719:SAMIE_RS11240
uniprot id: A0A494W5P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

135719:SAMIE RS05665
gene id: 135719:SAMIE_RS05665
uniprot id: A0A494WAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

135719:SAMIE RS00775
gene id: 135719:SAMIE_RS00775
uniprot id: A0A494W7P1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

135719:SAMIE RS16425
gene id: 135719:SAMIE_RS16425
uniprot id: A0A494WER8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

135719:SAMIE RS01285
gene id: 135719:SAMIE_RS01285
uniprot id: A0A494W7V5
names: Similarity
messages: Belongs to the serpin family.

135719:SAMIE RS00500
gene id: 135719:SAMIE_RS00500
uniprot id: A0A494W877
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

135719:SAMIE RS10420
gene id: 135719:SAMIE_RS10420
uniprot id: A0A494W2C5
names: Function
messages: Multidrug efflux pump.

135719:SAMIE RS13560
gene id: 135719:SAMIE_RS13560
uniprot id: A0A494W2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

135719:SAMIE RS06425
gene id: 135719:SAMIE_RS06425
uniprot id: A0A494VYZ7
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS09450
gene id: 135719:SAMIE_RS09450
uniprot id: A0A494WCC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

135719:SAMIE RS15745
gene id: 135719:SAMIE_RS15745
uniprot id: A0A494W422
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

135719:SAMIE RS10190
gene id: 135719:SAMIE_RS10190
uniprot id: A0A494WC10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

135719:SAMIE RS16240
gene id: 135719:SAMIE_RS16240
uniprot id: A0A494WF13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

135719:SAMIE RS11915
gene id: 135719:SAMIE_RS11915
uniprot id: A0A494W7S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

135719:SAMIE RS13745
gene id: 135719:SAMIE_RS13745
uniprot id: A0A494W8M8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

135719:SAMIE RS22475
gene id: 135719:SAMIE_RS22475
uniprot id: A0A494W7E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

135719:SAMIE RS19730
gene id: 135719:SAMIE_RS19730
uniprot id: A0A494W706
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

135719:SAMIE RS04235
gene id: 135719:SAMIE_RS04235
uniprot id: A0A494W1R3
names: Similarity
messages: Belongs to the virb1 family.

135719:SAMIE RS14300
gene id: 135719:SAMIE_RS14300
uniprot id: A0A494W6U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

135719:SAMIE RS11115
gene id: 135719:SAMIE_RS11115
uniprot id: A0A494W578
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

135719:SAMIE RS13415
gene id: 135719:SAMIE_RS13415
uniprot id: A0A494VZ17
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

135719:SAMIE RS19735
gene id: 135719:SAMIE_RS19735
uniprot id: A0A494WG83
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

135719:SAMIE RS23005
gene id: 135719:SAMIE_RS23005
uniprot id: A0A494WBR5
names: Similarity
messages: Belongs to the transposase 7 family.

135719:SAMIE RS15445
gene id: 135719:SAMIE_RS15445
uniprot id: A0A494WEQ0
names: Similarity
messages: Belongs to the ArsC family.

135719:SAMIE RS05425
gene id: 135719:SAMIE_RS05425
uniprot id: A0A494WB48
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

135719:SAMIE RS13815
gene id: 135719:SAMIE_RS13815
uniprot id: A0A494W7L6
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

135719:SAMIE RS12010
gene id: 135719:SAMIE_RS12010
uniprot id: A0A494WD68
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

135719:SAMIE RS07015
gene id: 135719:SAMIE_RS07015
uniprot id: A0A494W0P8
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

135719:SAMIE RS18715
gene id: 135719:SAMIE_RS18715
uniprot id: A0A494W5H4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

135719:SAMIE RS14600
gene id: 135719:SAMIE_RS14600
uniprot id: A0A494W4E9
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS00790
gene id: 135719:SAMIE_RS00790
uniprot id: A0A494VW77
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

135719:SAMIE RS05300
gene id: 135719:SAMIE_RS05300
uniprot id: A0A494W2S3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

135719:SAMIE RS14985
gene id: 135719:SAMIE_RS14985
uniprot id: A0A494W3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

135719:SAMIE RS16845
gene id: 135719:SAMIE_RS16845
uniprot id: A0A494WFA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS08130
gene id: 135719:SAMIE_RS08130
uniprot id: A0A494VZV7
names: Similarity
messages: Belongs to the MobA/MobL family.

135719:SAMIE RS03165
gene id: 135719:SAMIE_RS03165
uniprot id: A0A494W1J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

135719:SAMIE RS17520
gene id: 135719:SAMIE_RS17520
uniprot id: A0A494W5U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

135719:SAMIE RS19075
gene id: 135719:SAMIE_RS19075
uniprot id: A0A494WGJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS10515
gene id: 135719:SAMIE_RS10515
uniprot id: A0A494W6Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

135719:SAMIE RS07630
gene id: 135719:SAMIE_RS07630
uniprot id: A0A494WC50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

135719:SAMIE RS18035
gene id: 135719:SAMIE_RS18035
uniprot id: A0A494WFP8
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS02780
gene id: 135719:SAMIE_RS02780
uniprot id: A0A494VX65
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS04930
gene id: 135719:SAMIE_RS04930
uniprot id: A0A494VYA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

135719:SAMIE RS15935
gene id: 135719:SAMIE_RS15935
uniprot id: A0A494W9P2
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS00270
gene id: 135719:SAMIE_RS00270
uniprot id: A0A494W7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

135719:SAMIE RS04820
gene id: 135719:SAMIE_RS04820
uniprot id: A0A494VZ17
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

135719:SAMIE RS03650
gene id: 135719:SAMIE_RS03650
uniprot id: A0A494VXP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

135719:SAMIE RS05175
gene id: 135719:SAMIE_RS05175
uniprot id: A0A494W499
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS16395
gene id: 135719:SAMIE_RS16395
uniprot id: A0A494W4D8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS22040
gene id: 135719:SAMIE_RS22040
uniprot id: A0A494W774
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS07640
gene id: 135719:SAMIE_RS07640
uniprot id: A0A494W0Z5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

135719:SAMIE RS11815
gene id: 135719:SAMIE_RS11815
uniprot id: A0A494WDW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

135719:SAMIE RS04190
gene id: 135719:SAMIE_RS04190
uniprot id: A0A494W3R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

135719:SAMIE RS03690
gene id: 135719:SAMIE_RS03690
uniprot id: A0A494W934
names: Similarity
messages: Belongs to the phosphohexose mutase family.

135719:SAMIE RS16230
gene id: 135719:SAMIE_RS16230
uniprot id: A0A494W454
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

135719:SAMIE RS02180
gene id: 135719:SAMIE_RS02180
uniprot id: A0A494W130
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

135719:SAMIE RS09660
gene id: 135719:SAMIE_RS09660
uniprot id: A0A494WCB8
names: Subcellular Location Annotation
messages: Membrane

135719:SAMIE RS09635
gene id: 135719:SAMIE_RS09635
uniprot id: A0A494W6K7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

135719:SAMIE RS21820
gene id: 135719:SAMIE_RS21820
uniprot id: A0A494WB04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

135719:SAMIE RS00570
gene id: 135719:SAMIE_RS00570
uniprot id: A0A494VW31
names: Similarity
messages: Belongs to the virb1 family.

135719:SAMIE RS04170
gene id: 135719:SAMIE_RS04170
uniprot id: A0A494VXZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS19500
gene id: 135719:SAMIE_RS19500
uniprot id: A0A494W9Z6
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 copper ion per subunit.
messages: Periplasm

135719:SAMIE RS02775
gene id: 135719:SAMIE_RS02775
uniprot id: A0A494VX71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

135719:SAMIE RS15610
gene id: 135719:SAMIE_RS15610
uniprot id: A0A494W3U7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

135719:SAMIE RS03410
gene id: 135719:SAMIE_RS03410
uniprot id: A0A494W7L6
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

135719:SAMIE RS04285
gene id: 135719:SAMIE_RS04285
uniprot id: A0A494W1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

135719:SAMIE RS10195
gene id: 135719:SAMIE_RS10195
uniprot id: A0A494W295
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

135719:SAMIE RS11270
gene id: 135719:SAMIE_RS11270
uniprot id: A0A494W1L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

135719:SAMIE RS03270
gene id: 135719:SAMIE_RS03270
uniprot id: A0A494W1M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

135719:SAMIE RS04505
gene id: 135719:SAMIE_RS04505
uniprot id: A0A494W2D8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

135719:SAMIE RS12070
gene id: 135719:SAMIE_RS12070
uniprot id: A0A494W348
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

135719:SAMIE RS11535
gene id: 135719:SAMIE_RS11535
uniprot id: A0A494WCK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

135719:SAMIE RS01860
gene id: 135719:SAMIE_RS01860
uniprot id: A0A494W9F7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

135719:SAMIE RS10800
gene id: 135719:SAMIE_RS10800
uniprot id: A0A494WCR8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

135719:SAMIE RS14220
gene id: 135719:SAMIE_RS14220
uniprot id: A0A494WDR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

135719:SAMIE RS18610
gene id: 135719:SAMIE_RS18610
uniprot id: A0A494W5G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

135719:SAMIE RS17850
gene id: 135719:SAMIE_RS17850
uniprot id: A0A494W5Z7
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

135719:SAMIE RS00745
gene id: 135719:SAMIE_RS00745
uniprot id: A0A494VW50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

135719:SAMIE RS14280
gene id: 135719:SAMIE_RS14280
uniprot id: A0A494WE48
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

135719:SAMIE RS10290
gene id: 135719:SAMIE_RS10290
uniprot id: A0A494W586
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

135719:SAMIE RS21665
gene id: 135719:SAMIE_RS21665
uniprot id: A0A494W7V4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.