132473:CP975 RS21055
gene id: 132473:CP975_RS21055
uniprot id: A0A5J6HS64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

132473:CP975 RS18365
gene id: 132473:CP975_RS18365
uniprot id: A0A5J6HLI0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

132473:CP975 RS29405
gene id: 132473:CP975_RS29405
uniprot id: A0A5J6HWT3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

132473:CP975 RS20645
gene id: 132473:CP975_RS20645
uniprot id: A0A5J6HK38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

132473:CP975 RS06365
gene id: 132473:CP975_RS06365
uniprot id: A0A5J6HFL1
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

132473:CP975 RS05440
gene id: 132473:CP975_RS05440
uniprot id: A0A5J6HIM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

132473:CP975 RS32545
gene id: 132473:CP975_RS32545
uniprot id: A0A5J6HT82
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

132473:CP975 RS17500
gene id: 132473:CP975_RS17500
uniprot id: A0A5J6HIG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

132473:CP975 RS01610
gene id: 132473:CP975_RS01610
uniprot id: A0A5J6HZJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

132473:CP975 RS27965
gene id: 132473:CP975_RS27965
uniprot id: A0A5J6HN31
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

132473:CP975 RS21005
gene id: 132473:CP975_RS21005
uniprot id: A0A5J6HHM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

132473:CP975 RS17810
gene id: 132473:CP975_RS17810
uniprot id: A0A5J6HHY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

132473:CP975 RS21085
gene id: 132473:CP975_RS21085
uniprot id: A0A5J6HML4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

132473:CP975 RS13385
gene id: 132473:CP975_RS13385
uniprot id: A0A5J6HGH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

132473:CP975 RS01855
gene id: 132473:CP975_RS01855
uniprot id: A0A5J6H8S3
names: Subcellular Location Annotation
messages: Membrane

132473:CP975 RS14650
gene id: 132473:CP975_RS14650
uniprot id: A0A5J6HJG8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

132473:CP975 RS05570
gene id: 132473:CP975_RS05570
uniprot id: A0A5J6HCT1
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

132473:CP975 RS09555
gene id: 132473:CP975_RS09555
uniprot id: A0A5J6HL33
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

132473:CP975 RS11925
gene id: 132473:CP975_RS11925
uniprot id: A0A5J6HM69
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

132473:CP975 RS26710
gene id: 132473:CP975_RS26710
uniprot id: A0A5J6HN66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

132473:CP975 RS11760
gene id: 132473:CP975_RS11760
uniprot id: A0A5J6HI51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

132473:CP975 RS20925
gene id: 132473:CP975_RS20925
uniprot id: A0A5J6HMW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

132473:CP975 RS09030
gene id: 132473:CP975_RS09030
uniprot id: A0A5J6HBT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

132473:CP975 RS09310
gene id: 132473:CP975_RS09310
uniprot id: A0A5J6HH49
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

132473:CP975 RS23355
gene id: 132473:CP975_RS23355
uniprot id: A0A5J6HVM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

132473:CP975 RS17655
gene id: 132473:CP975_RS17655
uniprot id: A0A5J6HKY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

132473:CP975 RS14090
gene id: 132473:CP975_RS14090
uniprot id: A0A5J6HE24
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

132473:CP975 RS20930
gene id: 132473:CP975_RS20930
uniprot id: A0A5J6HMI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

132473:CP975 RS05660
gene id: 132473:CP975_RS05660
uniprot id: A0A5J6HAD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

132473:CP975 RS31680
gene id: 132473:CP975_RS31680
uniprot id: A0A5J6HRM0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

132473:CP975 RS13985
gene id: 132473:CP975_RS13985
uniprot id: A0A5J6HJ25
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

132473:CP975 RS05475
gene id: 132473:CP975_RS05475
uniprot id: A0A5J6HFC3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

132473:CP975 RS24495
gene id: 132473:CP975_RS24495
uniprot id: A0A5J6HPJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

132473:CP975 RS14710
gene id: 132473:CP975_RS14710
uniprot id: A0A5J6HJI6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

132473:CP975 RS09040
gene id: 132473:CP975_RS09040
uniprot id: A0A5J6HDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

132473:CP975 RS05380
gene id: 132473:CP975_RS05380
uniprot id: A0A5J6HIL4
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

132473:CP975 RS19305
gene id: 132473:CP975_RS19305
uniprot id: A0A5J6HIM3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

132473:CP975 RS11515
gene id: 132473:CP975_RS11515
uniprot id: A0A5J6HCY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

132473:CP975 RS20955
gene id: 132473:CP975_RS20955
uniprot id: A0A5J6HHM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

132473:CP975 RS25680
gene id: 132473:CP975_RS25680
uniprot id: A0A5J6HQ91
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

132473:CP975 RS11755
gene id: 132473:CP975_RS11755
uniprot id: A0A5J6HU16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

132473:CP975 RS15775
gene id: 132473:CP975_RS15775
uniprot id: A0A5J6HET6
names: Subcellular Location Annotation
messages: Cytoplasm

132473:CP975 RS06325
gene id: 132473:CP975_RS06325
uniprot id: A0A5J6HFR7
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

132473:CP975 RS07360
gene id: 132473:CP975_RS07360
uniprot id: A0A5J6HCP0
names: Similarity
messages: Belongs to the TlyA family.

132473:CP975 RS05435
gene id: 132473:CP975_RS05435
uniprot id: A0A5J6HA38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

132473:CP975 RS25785
gene id: 132473:CP975_RS25785
uniprot id: A0A5J6HQB0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

132473:CP975 RS21030
gene id: 132473:CP975_RS21030
uniprot id: A0A5J6HMZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

132473:CP975 RS11240
gene id: 132473:CP975_RS11240
uniprot id: A0A5J6HHX4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

132473:CP975 RS14910
gene id: 132473:CP975_RS14910
uniprot id: A0A5J6HJS2
names: Subcellular Location Annotation
messages: Membrane

132473:CP975 RS06110
gene id: 132473:CP975_RS06110
uniprot id: A0A5J6HAE2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

132473:CP975 RS13380
gene id: 132473:CP975_RS13380
uniprot id: A0A5J6HJ02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

132473:CP975 RS24465
gene id: 132473:CP975_RS24465
uniprot id: A0A5J6HU80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

132473:CP975 RS20880
gene id: 132473:CP975_RS20880
uniprot id: A0A5J6HK76
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

132473:CP975 RS06290
gene id: 132473:CP975_RS06290
uniprot id: A0A5J6HJ06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

132473:CP975 RS08230
gene id: 132473:CP975_RS08230
uniprot id: A0A5J6HGN7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

132473:CP975 RS18495
gene id: 132473:CP975_RS18495
uniprot id: A0A5J6HL56
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

132473:CP975 RS30250
gene id: 132473:CP975_RS30250
uniprot id: A0A5J6HLS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

132473:CP975 RS08125
gene id: 132473:CP975_RS08125
uniprot id: A0A5J6HGD8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

132473:CP975 RS07545
gene id: 132473:CP975_RS07545
uniprot id: A0A5J6HB46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

132473:CP975 RS18655
gene id: 132473:CP975_RS18655
uniprot id: A0A5J6HLC4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

132473:CP975 RS01605
gene id: 132473:CP975_RS01605
uniprot id: A0A5J6H8M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

132473:CP975 RS22065
gene id: 132473:CP975_RS22065
uniprot id: A0A5J6HI46
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

132473:CP975 RS19575
gene id: 132473:CP975_RS19575
uniprot id: A0A5J6I0K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

132473:CP975 RS20975
gene id: 132473:CP975_RS20975
uniprot id: A0A5J6HMY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

132473:CP975 RS23765
gene id: 132473:CP975_RS23765
uniprot id: A0A5J6HPD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

132473:CP975 RS21925
gene id: 132473:CP975_RS21925
uniprot id: A0A5J6HMW5
names: Subcellular Location Annotation
messages: Membrane

132473:CP975 RS25645
gene id: 132473:CP975_RS25645
uniprot id: A0A5J6HPS1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

132473:CP975 RS20960
gene id: 132473:CP975_RS20960
uniprot id: A0A5J6HRL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

132473:CP975 RS20725
gene id: 132473:CP975_RS20725
uniprot id: A0A5J6HJF8
names: Similarity
messages: Belongs to the UPF0234 family.

132473:CP975 RS07565
gene id: 132473:CP975_RS07565
uniprot id: A0A5J6HG43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

132473:CP975 RS06355
gene id: 132473:CP975_RS06355
uniprot id: A0A5J6HAN4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

132473:CP975 RS18420
gene id: 132473:CP975_RS18420
uniprot id: A0A5J6HLJ0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

132473:CP975 RS20825
gene id: 132473:CP975_RS20825
uniprot id: A0A5J6HK62
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

132473:CP975 RS26645
gene id: 132473:CP975_RS26645
uniprot id: A0A5J6HQV9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

132473:CP975 RS13370
gene id: 132473:CP975_RS13370
uniprot id: A0A5J6HDQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

132473:CP975 RS20990
gene id: 132473:CP975_RS20990
uniprot id: A0A5J6HMF7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

132473:CP975 RS22550
gene id: 132473:CP975_RS22550
uniprot id: A0A5J6HT46
names: Similarity
messages: Belongs to the FBPase class 2 family.

132473:CP975 RS09425
gene id: 132473:CP975_RS09425
uniprot id: A0A5J6HH64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

132473:CP975 RS13780
gene id: 132473:CP975_RS13780
uniprot id: A0A5J6HMM7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

132473:CP975 RS12135
gene id: 132473:CP975_RS12135
uniprot id: A0A5J6HIB3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

132473:CP975 RS23680
gene id: 132473:CP975_RS23680
uniprot id: A0A5J6HTM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

132473:CP975 RS33210
gene id: 132473:CP975_RS33210
uniprot id: A0A5J6HN60
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

132473:CP975 RS16095
gene id: 132473:CP975_RS16095
uniprot id: A0A5J6HEZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

132473:CP975 RS15290
gene id: 132473:CP975_RS15290
uniprot id: A0A5J6HJP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

132473:CP975 RS20650
gene id: 132473:CP975_RS20650
uniprot id: A0A5J6HMA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

132473:CP975 RS30940
gene id: 132473:CP975_RS30940
uniprot id: A0A5J6HPG2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

132473:CP975 RS26150
gene id: 132473:CP975_RS26150
uniprot id: A0A5J6HJR7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

132473:CP975 RS04565
gene id: 132473:CP975_RS04565
uniprot id: A0A5J6HEZ2
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

132473:CP975 RS21045
gene id: 132473:CP975_RS21045
uniprot id: A0A5J6HMG9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

132473:CP975 RS21265
gene id: 132473:CP975_RS21265
uniprot id: A0A5J6HKE7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

132473:CP975 RS21010
gene id: 132473:CP975_RS21010
uniprot id: A0A5J6HRM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

132473:CP975 RS21220
gene id: 132473:CP975_RS21220
uniprot id: A0A5J6HMF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

132473:CP975 RS24480
gene id: 132473:CP975_RS24480
uniprot id: A0A5J6HLE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

132473:CP975 RS21040
gene id: 132473:CP975_RS21040
uniprot id: A0A5J6HKA6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

132473:CP975 RS08110
gene id: 132473:CP975_RS08110
uniprot id: A0A5J6HG93
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

132473:CP975 RS09785
gene id: 132473:CP975_RS09785
uniprot id: A0A5J6HRF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

132473:CP975 RS07455
gene id: 132473:CP975_RS07455
uniprot id: A0A5J6HG23
names: Subcellular Location Annotation
messages: Membrane

132473:CP975 RS01745
gene id: 132473:CP975_RS01745
uniprot id: A0A5J6HUN0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

132473:CP975 RS05880
gene id: 132473:CP975_RS05880
uniprot id: A0A5J6HAA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

132473:CP975 RS22475
gene id: 132473:CP975_RS22475
uniprot id: A0A5J6HN62
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

132473:CP975 RS25705
gene id: 132473:CP975_RS25705
uniprot id: A0A5J6HUU4
names: Similarity
messages: Belongs to the acylphosphatase family.

132473:CP975 RS21075
gene id: 132473:CP975_RS21075
uniprot id: A0A5J6HHB6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

132473:CP975 RS24560
gene id: 132473:CP975_RS24560
uniprot id: A0A5J6HPK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

132473:CP975 RS16310
gene id: 132473:CP975_RS16310
uniprot id: A0A5J6HK75
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

132473:CP975 RS11690
gene id: 132473:CP975_RS11690
uniprot id: A0A5J6HD06
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

132473:CP975 RS24420
gene id: 132473:CP975_RS24420
uniprot id: A0A5J6HJ49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

132473:CP975 RS15770
gene id: 132473:CP975_RS15770
uniprot id: A0A5J6HP29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

132473:CP975 RS13270
gene id: 132473:CP975_RS13270
uniprot id: A0A5J6HDN9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

132473:CP975 RS21000
gene id: 132473:CP975_RS21000
uniprot id: A0A5J6HS52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

132473:CP975 RS20915
gene id: 132473:CP975_RS20915
uniprot id: A0A5J6HJJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

132473:CP975 RS20900
gene id: 132473:CP975_RS20900
uniprot id: A0A5J6HHL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

132473:CP975 RS12945
gene id: 132473:CP975_RS12945
uniprot id: A0A5J6HGA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

132473:CP975 RS07855
gene id: 132473:CP975_RS07855
uniprot id: A0A5J6HGG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

132473:CP975 RS22285
gene id: 132473:CP975_RS22285
uniprot id: A0A5J6HKB1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

132473:CP975 RS08205
gene id: 132473:CP975_RS08205
uniprot id: A0A5J6HBF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

132473:CP975 RS25855
gene id: 132473:CP975_RS25855
uniprot id: A0A5J6HPH4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

132473:CP975 RS29685
gene id: 132473:CP975_RS29685
uniprot id: A0A5J6HVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

132473:CP975 RS19820
gene id: 132473:CP975_RS19820
uniprot id: A0A5J6HR01
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

132473:CP975 RS12285
gene id: 132473:CP975_RS12285
uniprot id: A0A5J6HIE1
names: Similarity
messages: Belongs to the citrate synthase family.

132473:CP975 RS20870
gene id: 132473:CP975_RS20870
uniprot id: A0A5J6HMV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

132473:CP975 RS34685
gene id: 132473:CP975_RS34685
uniprot id: A0A5J6HP21
names: Subcellular Location Annotation
messages: Membrane

132473:CP975 RS23670
gene id: 132473:CP975_RS23670
uniprot id: A0A5J6HNR2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

132473:CP975 RS21260
gene id: 132473:CP975_RS21260
uniprot id: A0A5J6HMP6
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

132473:CP975 RS05565
gene id: 132473:CP975_RS05565
uniprot id: A0A5J6HF67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

132473:CP975 RS24550
gene id: 132473:CP975_RS24550
uniprot id: A0A5J6HIV8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

132473:CP975 RS10675
gene id: 132473:CP975_RS10675
uniprot id: A0A5J6HEC8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

132473:CP975 RS09085
gene id: 132473:CP975_RS09085
uniprot id: A0A5J6HBT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

132473:CP975 RS04925
gene id: 132473:CP975_RS04925
uniprot id: A0A5J6HEQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

132473:CP975 RS25885
gene id: 132473:CP975_RS25885
uniprot id: A0A5J6HQD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

132473:CP975 RS04430
gene id: 132473:CP975_RS04430
uniprot id: A0A5J6HEQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

132473:CP975 RS11465
gene id: 132473:CP975_RS11465
uniprot id: A0A5J6HFM9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

132473:CP975 RS21015
gene id: 132473:CP975_RS21015
uniprot id: A0A5J6HJP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

132473:CP975 RS11630
gene id: 132473:CP975_RS11630
uniprot id: A0A5J6HLM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

132473:CP975 RS24425
gene id: 132473:CP975_RS24425
uniprot id: A0A5J6HTE1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

132473:CP975 RS21090
gene id: 132473:CP975_RS21090
uniprot id: A0A5J6HKB6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

132473:CP975 RS09830
gene id: 132473:CP975_RS09830
uniprot id: A0A5J6HHD2
names: Similarity
messages: Belongs to the glutamine synthetase family.

132473:CP975 RS09640
gene id: 132473:CP975_RS09640
uniprot id: A0A5J6HUS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

132473:CP975 RS20995
gene id: 132473:CP975_RS20995
uniprot id: A0A5J6HMB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

132473:CP975 RS26190
gene id: 132473:CP975_RS26190
uniprot id: A0A5J6HK16
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

132473:CP975 RS25495
gene id: 132473:CP975_RS25495
uniprot id: A0A5J6HQ24
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

132473:CP975 RS05755
gene id: 132473:CP975_RS05755
uniprot id: A0A5J6HA87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

132473:CP975 RS21685
gene id: 132473:CP975_RS21685
uniprot id: A0A5J6HHL4
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

132473:CP975 RS16305
gene id: 132473:CP975_RS16305
uniprot id: A0A5J6HHY1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

132473:CP975 RS20465
gene id: 132473:CP975_RS20465
uniprot id: A0A5J6HM73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

132473:CP975 RS19595
gene id: 132473:CP975_RS19595
uniprot id: A0A5J6HRF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

132473:CP975 RS18080
gene id: 132473:CP975_RS18080
uniprot id: A0A5J6HL70
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

132473:CP975 RS21035
gene id: 132473:CP975_RS21035
uniprot id: A0A5J6HMK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

132473:CP975 RS20885
gene id: 132473:CP975_RS20885
uniprot id: A0A5J6HMD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

132473:CP975 RS23750
gene id: 132473:CP975_RS23750
uniprot id: A0A5J6HT37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

132473:CP975 RS21070
gene id: 132473:CP975_RS21070
uniprot id: A0A5J6HJQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

132473:CP975 RS20470
gene id: 132473:CP975_RS20470
uniprot id: A0A5J6HM23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

132473:CP975 RS11695
gene id: 132473:CP975_RS11695
uniprot id: A0A5J6HIC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

132473:CP975 RS08735
gene id: 132473:CP975_RS08735
uniprot id: A0A5J6HKM3
names: Subcellular Location Annotation
messages: Cytoplasm

132473:CP975 RS08210
gene id: 132473:CP975_RS08210
uniprot id: A0A5J6HGA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

132473:CP975 RS08615
gene id: 132473:CP975_RS08615
uniprot id: A0A5J6HK74
names: Subcellular Location Annotation
messages: Membrane

132473:CP975 RS20935
gene id: 132473:CP975_RS20935
uniprot id: A0A5J6HK89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

132473:CP975 RS11640
gene id: 132473:CP975_RS11640
uniprot id: A0A5J6HCZ8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

132473:CP975 RS29905
gene id: 132473:CP975_RS29905
uniprot id: A0A5J6HSD1
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

132473:CP975 RS26415
gene id: 132473:CP975_RS26415
uniprot id: A0A5J6HPQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

132473:CP975 RS26375
gene id: 132473:CP975_RS26375
uniprot id: A0A5J6HUC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

132473:CP975 RS05640
gene id: 132473:CP975_RS05640
uniprot id: A0A5J6HJ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

132473:CP975 RS17510
gene id: 132473:CP975_RS17510
uniprot id: A0A5J6HKN0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

132473:CP975 RS02400
gene id: 132473:CP975_RS02400
uniprot id: A0A5J6HHG9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

132473:CP975 RS23195
gene id: 132473:CP975_RS23195
uniprot id: A0A5J6HI86
names: Subcellular Location Annotation
messages: Membrane

132473:CP975 RS20985
gene id: 132473:CP975_RS20985
uniprot id: A0A5J6HK96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

132473:CP975 RS23225
gene id: 132473:CP975_RS23225
uniprot id: A0A5J6HND0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

132473:CP975 RS17485
gene id: 132473:CP975_RS17485
uniprot id: A0A5J6HFJ6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

132473:CP975 RS20285
gene id: 132473:CP975_RS20285
uniprot id: A0A5J6HLZ1
names: Subcellular Location Annotation
messages: Cytoplasm

132473:CP975 RS20860
gene id: 132473:CP975_RS20860
uniprot id: A0A5J6HH71
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

132473:CP975 RS22625
gene id: 132473:CP975_RS22625
uniprot id: A0A5J6HSH3
names: Subcellular Location Annotation
messages: Cytoplasm

132473:CP975 RS21065
gene id: 132473:CP975_RS21065
uniprot id: A0A5J6HRN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

132473:CP975 RS05425
gene id: 132473:CP975_RS05425
uniprot id: A0A5J6HFB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

132473:CP975 RS19605
gene id: 132473:CP975_RS19605
uniprot id: A0A5J6HQQ9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

132473:CP975 RS21460
gene id: 132473:CP975_RS21460
uniprot id: A0A5J6HHV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

132473:CP975 RS20905
gene id: 132473:CP975_RS20905
uniprot id: A0A5J6HRK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

132473:CP975 RS09005
gene id: 132473:CP975_RS09005
uniprot id: A0A5J6HEH0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

132473:CP975 RS08235
gene id: 132473:CP975_RS08235
uniprot id: A0A5J6HKE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

132473:CP975 RS25180
gene id: 132473:CP975_RS25180
uniprot id: A0A5J6HP61
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

132473:CP975 RS16465
gene id: 132473:CP975_RS16465
uniprot id: A0A5J6HI06
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

132473:CP975 RS22300
gene id: 132473:CP975_RS22300
uniprot id: A0A5J6HN79
names: Subcellular Location Annotation
messages: Cytoplasm

132473:CP975 RS25985
gene id: 132473:CP975_RS25985
uniprot id: A0A5J6HM39
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

132473:CP975 RS20965
gene id: 132473:CP975_RS20965
uniprot id: A0A5J6HJN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

132473:CP975 RS14820
gene id: 132473:CP975_RS14820
uniprot id: A0A5J6HNK5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

132473:CP975 RS09010
gene id: 132473:CP975_RS09010
uniprot id: A0A5J6HGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

132473:CP975 RS17640
gene id: 132473:CP975_RS17640
uniprot id: A0A5J6HFN1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

132473:CP975 RS25720
gene id: 132473:CP975_RS25720
uniprot id: A0A5J6HU00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

132473:CP975 RS06255
gene id: 132473:CP975_RS06255
uniprot id: A0A5J6HFJ1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

132473:CP975 RS28725
gene id: 132473:CP975_RS28725
uniprot id: A0A5J6HRW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

132473:CP975 RS18665
gene id: 132473:CP975_RS18665
uniprot id: A0A5J6HQY4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

132473:CP975 RS29280
gene id: 132473:CP975_RS29280
uniprot id: P13249
names: Function
messages: Detoxification of puromycin.

132473:CP975 RS05495
gene id: 132473:CP975_RS05495
uniprot id: A0A5J6HBM8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

132473:CP975 RS25790
gene id: 132473:CP975_RS25790
uniprot id: A0A5J6HQ82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

132473:CP975 RS25055
gene id: 132473:CP975_RS25055
uniprot id: A0A5J6HMC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

132473:CP975 RS23735
gene id: 132473:CP975_RS23735
uniprot id: A0A5J6HTN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

132473:CP975 RS20970
gene id: 132473:CP975_RS20970
uniprot id: A0A5J6HH96
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

132473:CP975 RS25270
gene id: 132473:CP975_RS25270
uniprot id: A0A5J6HQ13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

132473:CP975 RS08845
gene id: 132473:CP975_RS08845
uniprot id: A0A5J6HKP4
names: Similarity
messages: Belongs to the TrpC family.

132473:CP975 RS30210
gene id: 132473:CP975_RS30210
uniprot id: A0A5J6HS54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

132473:CP975 RS06285
gene id: 132473:CP975_RS06285
uniprot id: A0A5J6HTI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

132473:CP975 RS20945
gene id: 132473:CP975_RS20945
uniprot id: A0A5J6HM99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

132473:CP975 RS07450
gene id: 132473:CP975_RS07450
uniprot id: A0A5J6HDP8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

132473:CP975 RS08880
gene id: 132473:CP975_RS08880
uniprot id: A0A5J6HGV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

132473:CP975 RS20980
gene id: 132473:CP975_RS20980
uniprot id: A0A5J6HMJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

132473:CP975 RS19620
gene id: 132473:CP975_RS19620
uniprot id: A0A5J6HM97
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

132473:CP975 RS21115
gene id: 132473:CP975_RS21115
uniprot id: A0A5J6HRQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

132473:CP975 RS11405
gene id: 132473:CP975_RS11405
uniprot id: A0A5J6HI70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

132473:CP975 RS20950
gene id: 132473:CP975_RS20950
uniprot id: A0A5J6HS40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

132473:CP975 RS05620
gene id: 132473:CP975_RS05620
uniprot id: A0A5J6HCU3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

132473:CP975 RS31750
gene id: 132473:CP975_RS31750
uniprot id: A0A5J6HXY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

132473:CP975 RS11375
gene id: 132473:CP975_RS11375
uniprot id: A0A5J6HZ46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

132473:CP975 RS22570
gene id: 132473:CP975_RS22570
uniprot id: A0A5J6HHZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

132473:CP975 RS11815
gene id: 132473:CP975_RS11815
uniprot id: A0A5J6HD24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

132473:CP975 RS19500
gene id: 132473:CP975_RS19500
uniprot id: A0A5J6HM76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

132473:CP975 RS19995
gene id: 132473:CP975_RS19995
uniprot id: A0A5J6HLZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

132473:CP975 RS26775
gene id: 132473:CP975_RS26775
uniprot id: A0A5J6HPU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

132473:CP975 RS20515
gene id: 132473:CP975_RS20515
uniprot id: A0A5J6HK10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

132473:CP975 RS25475
gene id: 132473:CP975_RS25475
uniprot id: A0A5J6HLV1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

132473:CP975 RS25805
gene id: 132473:CP975_RS25805
uniprot id: A0A5J6HPF9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

132473:CP975 RS20920
gene id: 132473:CP975_RS20920
uniprot id: A0A5J6HH85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

132473:CP975 RS21080
gene id: 132473:CP975_RS21080
uniprot id: A0A5J6HN00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

132473:CP975 RS05170
gene id: 132473:CP975_RS05170
uniprot id: A0A5J6HEU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

132473:CP975 RS05290
gene id: 132473:CP975_RS05290
uniprot id: A0A5J6HEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

132473:CP975 RS06115
gene id: 132473:CP975_RS06115
uniprot id: A0A5J6HIX6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

132473:CP975 RS19855
gene id: 132473:CP975_RS19855
uniprot id: A0A5J6HM03
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

132473:CP975 RS09045
gene id: 132473:CP975_RS09045
uniprot id: A0A5J6HBU0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

132473:CP975 RS09430
gene id: 132473:CP975_RS09430
uniprot id: A0A5J6HL05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

132473:CP975 RS23835
gene id: 132473:CP975_RS23835
uniprot id: A0A5J6HNU5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

132473:CP975 RS21025
gene id: 132473:CP975_RS21025
uniprot id: A0A5J6HHA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

132473:CP975 RS09405
gene id: 132473:CP975_RS09405
uniprot id: A0A5J6HH44
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

132473:CP975 RS08170
gene id: 132473:CP975_RS08170
uniprot id: A0A5J6HE28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

132473:CP975 RS13575
gene id: 132473:CP975_RS13575
uniprot id: A0A5J6HJ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

132473:CP975 RS09410
gene id: 132473:CP975_RS09410
uniprot id: A0A5J6HEP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane