1324350:AOY20 RS08935
gene id: 1324350:AOY20_RS08935
uniprot id: A0A0N9VZL5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1324350:AOY20 RS00475
gene id: 1324350:AOY20_RS00475
uniprot id: A0A0N9VVR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1324350:AOY20 RS09935
gene id: 1324350:AOY20_RS09935
uniprot id: A0A0N9VEY9
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1324350:AOY20 RS13215
gene id: 1324350:AOY20_RS13215
uniprot id: A0A0N9VFT3
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Involved in pyrimidine catabolism. Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously. RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.

1324350:AOY20 RS01270
gene id: 1324350:AOY20_RS01270
uniprot id: A0A0N9VZW2
names: Similarity
messages: Belongs to the YggT family.

1324350:AOY20 RS08490
gene id: 1324350:AOY20_RS08490
uniprot id: A0A0N9VQC5
names: Similarity
messages: Belongs to the peptidase S49 family.

1324350:AOY20 RS09275
gene id: 1324350:AOY20_RS09275
uniprot id: A0A0N9W3S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

1324350:AOY20 RS04745
gene id: 1324350:AOY20_RS04745
uniprot id: A0A0N9V6Q3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1324350:AOY20 RS04250
gene id: 1324350:AOY20_RS04250
uniprot id: A0A0N9W1A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1324350:AOY20 RS10365
gene id: 1324350:AOY20_RS10365
uniprot id: A0A0N9W462
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1324350:AOY20 RS06235
gene id: 1324350:AOY20_RS06235
uniprot id: A0A0N9W0W8
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1324350:AOY20 RS01915
gene id: 1324350:AOY20_RS01915
uniprot id: A0A0N9VAX7
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS10500
gene id: 1324350:AOY20_RS10500
uniprot id: A0A0N9VRE9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1324350:AOY20 RS05670
gene id: 1324350:AOY20_RS05670
uniprot id: A0A0N9W211
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1324350:AOY20 RS02825
gene id: 1324350:AOY20_RS02825
uniprot id: A0A0N9VMG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1324350:AOY20 RS09000
gene id: 1324350:AOY20_RS09000
uniprot id: A0A0N9VE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS08250
gene id: 1324350:AOY20_RS08250
uniprot id: A0A0N9W483
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1324350:AOY20 RS01745
gene id: 1324350:AOY20_RS01745
uniprot id: A0A0N9VYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1324350:AOY20 RS12205
gene id: 1324350:AOY20_RS12205
uniprot id: A0A0N9W0X2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS12865
gene id: 1324350:AOY20_RS12865
uniprot id: A0A0N9WFV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

1324350:AOY20 RS01890
gene id: 1324350:AOY20_RS01890
uniprot id: A0A0N9VT82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1324350:AOY20 RS08180
gene id: 1324350:AOY20_RS08180
uniprot id: A0A0N9VQ86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1324350:AOY20 RS03965
gene id: 1324350:AOY20_RS03965
uniprot id: A0A0N7GXH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1324350:AOY20 RS04305
gene id: 1324350:AOY20_RS04305
uniprot id: A0A0N9VB82
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1324350:AOY20 RS01730
gene id: 1324350:AOY20_RS01730
uniprot id: A0A0N7GXC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1324350:AOY20 RS08555
gene id: 1324350:AOY20_RS08555
uniprot id: A0A0N7GXT0
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1324350:AOY20 RS13345
gene id: 1324350:AOY20_RS13345
uniprot id: A0A0N9W3M9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1324350:AOY20 RS08415
gene id: 1324350:AOY20_RS08415
uniprot id: A0A0N7GXS7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS01760
gene id: 1324350:AOY20_RS01760
uniprot id: A0A0N9W048
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS03250
gene id: 1324350:AOY20_RS03250
uniprot id: A0A0N9VZD3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1324350:AOY20 RS03670
gene id: 1324350:AOY20_RS03670
uniprot id: A0A0N9V647
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1324350:AOY20 RS06910
gene id: 1324350:AOY20_RS06910
uniprot id: A0A0N9W2Q6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1324350:AOY20 RS02830
gene id: 1324350:AOY20_RS02830
uniprot id: A0A0N9VWV4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.

1324350:AOY20 RS00295
gene id: 1324350:AOY20_RS00295
uniprot id: A0A0N7GX96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1324350:AOY20 RS08265
gene id: 1324350:AOY20_RS08265
uniprot id: A0A0N9W1P1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1324350:AOY20 RS08225
gene id: 1324350:AOY20_RS08225
uniprot id: A0A0N9V8M6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS01160
gene id: 1324350:AOY20_RS01160
uniprot id: A0A0N9VAI8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1324350:AOY20 RS12980
gene id: 1324350:AOY20_RS12980
uniprot id: A0A0N9W3T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1324350:AOY20 RS12935
gene id: 1324350:AOY20_RS12935
uniprot id: A0A0N9WFV9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS04465
gene id: 1324350:AOY20_RS04465
uniprot id: A0A0N9VZY8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1324350:AOY20 RS07335
gene id: 1324350:AOY20_RS07335
uniprot id: A0A0N7GXQ4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS06655
gene id: 1324350:AOY20_RS06655
uniprot id: A0A0N9W150
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1324350:AOY20 RS13490
gene id: 1324350:AOY20_RS13490
uniprot id: A0A0N9VYE5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1324350:AOY20 RS13820
gene id: 1324350:AOY20_RS13820
uniprot id: A0A0N9VSR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1324350:AOY20 RS08945
gene id: 1324350:AOY20_RS08945
uniprot id: A0A0N9VE49
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1324350:AOY20 RS09800
gene id: 1324350:AOY20_RS09800
uniprot id: A0A0N7GXV8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1324350:AOY20 RS12220
gene id: 1324350:AOY20_RS12220
uniprot id: A0A0N9W369
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1324350:AOY20 RS05610
gene id: 1324350:AOY20_RS05610
uniprot id: A0A0N9VD66
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1324350:AOY20 RS14195
gene id: 1324350:AOY20_RS14195
uniprot id: A0A0N7GY59
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS12230
gene id: 1324350:AOY20_RS12230
uniprot id: A0A0N9VFV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS03945
gene id: 1324350:AOY20_RS03945
uniprot id: A0A0N9VXD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1324350:AOY20 RS05515
gene id: 1324350:AOY20_RS05515
uniprot id: A0A0N9W0E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1324350:AOY20 RS01500
gene id: 1324350:AOY20_RS01500
uniprot id: A0A0N9VYF7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1324350:AOY20 RS08515
gene id: 1324350:AOY20_RS08515
uniprot id: A0A0N9W232
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1324350:AOY20 RS10205
gene id: 1324350:AOY20_RS10205
uniprot id: A0A0N9W030
names: Similarity
messages: Belongs to the peptidase M16 family.

1324350:AOY20 RS11585
gene id: 1324350:AOY20_RS11585
uniprot id: A0A0N9VXQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1324350:AOY20 RS02485
gene id: 1324350:AOY20_RS02485
uniprot id: A0A0N9VTJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1324350:AOY20 RS02850
gene id: 1324350:AOY20_RS02850
uniprot id: A0A0N9VZ44
names: Similarity
messages: Belongs to the GSP N family.

1324350:AOY20 RS12370
gene id: 1324350:AOY20_RS12370
uniprot id: A0A0N9W4Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS04625
gene id: 1324350:AOY20_RS04625
uniprot id: A0A0N9VNB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1324350:AOY20 RS01095
gene id: 1324350:AOY20_RS01095
uniprot id: A0A0N9VAH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1324350:AOY20 RS11635
gene id: 1324350:AOY20_RS11635
uniprot id: A0A0N9W4N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1324350:AOY20 RS02680
gene id: 1324350:AOY20_RS02680
uniprot id: A0A0N9VME3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1324350:AOY20 RS12275
gene id: 1324350:AOY20_RS12275
uniprot id: A0A0N7GY15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

1324350:AOY20 RS06580
gene id: 1324350:AOY20_RS06580
uniprot id: A0A0N9VPD9
names: Similarity
messages: Belongs to the YkuD family.

1324350:AOY20 RS05640
gene id: 1324350:AOY20_RS05640
uniprot id: A0A0N9VY53
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1324350:AOY20 RS09875
gene id: 1324350:AOY20_RS09875
uniprot id: A0A0N9W3Z5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1324350:AOY20 RS01965
gene id: 1324350:AOY20_RS01965
uniprot id: A0A0N9VWH0
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1324350:AOY20 RS09695
gene id: 1324350:AOY20_RS09695
uniprot id: A0A0N9VEF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1324350:AOY20 RS12180
gene id: 1324350:AOY20_RS12180
uniprot id: A0A0N9W4W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1324350:AOY20 RS00105
gene id: 1324350:AOY20_RS00105
uniprot id: A0A0N9VA02
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS07345
gene id: 1324350:AOY20_RS07345
uniprot id: A0A0N9V865
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS04010
gene id: 1324350:AOY20_RS04010
uniprot id: A0A0N9VBX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1324350:AOY20 RS06770
gene id: 1324350:AOY20_RS06770
uniprot id: A0A0N9WD66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1324350:AOY20 RS00875
gene id: 1324350:AOY20_RS00875
uniprot id: A0A0N9VY16
names: Similarity
messages: Belongs to the UPF0145 family.

1324350:AOY20 RS00800
gene id: 1324350:AOY20_RS00800
uniprot id: A0A0N9VAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1324350:AOY20 RS05390
gene id: 1324350:AOY20_RS05390
uniprot id: A0A0N9WCD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1324350:AOY20 RS05435
gene id: 1324350:AOY20_RS05435
uniprot id: A0A0N9VGV6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1324350:AOY20 RS08860
gene id: 1324350:AOY20_RS08860
uniprot id: A0A0N9V8W4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1324350:AOY20 RS13000
gene id: 1324350:AOY20_RS13000
uniprot id: A0A0N9VG58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1324350:AOY20 RS07700
gene id: 1324350:AOY20_RS07700
uniprot id: A0A0N9VDQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS13470
gene id: 1324350:AOY20_RS13470
uniprot id: A0A0N9WG56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1324350:AOY20 RS02770
gene id: 1324350:AOY20_RS02770
uniprot id: A0A0N9WB28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1324350:AOY20 RS04520
gene id: 1324350:AOY20_RS04520
uniprot id: A0A0N9VC76
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1324350:AOY20 RS12025
gene id: 1324350:AOY20_RS12025
uniprot id: A0A0N9W0V1
names: Similarity
messages: Belongs to the HesB/IscA family.

1324350:AOY20 RS08280
gene id: 1324350:AOY20_RS08280
uniprot id: A0A0N7GXS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1324350:AOY20 RS00145
gene id: 1324350:AOY20_RS00145
uniprot id: A0A0N9VS98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1324350:AOY20 RS12695
gene id: 1324350:AOY20_RS12695
uniprot id: A0A0N9VAE4
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1324350:AOY20 RS00050
gene id: 1324350:AOY20_RS00050
uniprot id: A0A0N9W9G4
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS02895
gene id: 1324350:AOY20_RS02895
uniprot id: A0A0N9VMH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1324350:AOY20 RS10630
gene id: 1324350:AOY20_RS10630
uniprot id: A0A0N9V9I8
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1324350:AOY20 RS12300
gene id: 1324350:AOY20_RS12300
uniprot id: A0A0N9W4Y4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1324350:AOY20 RS08590
gene id: 1324350:AOY20_RS08590
uniprot id: A0A0N9WE37
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1324350:AOY20 RS14125
gene id: 1324350:AOY20_RS14125
uniprot id: A0A0N9VYM4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1324350:AOY20 RS10935
gene id: 1324350:AOY20_RS10935
uniprot id: A0A0N9VFC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1324350:AOY20 RS14275
gene id: 1324350:AOY20_RS14275
uniprot id: A0A0N9VXK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1324350:AOY20 RS03775
gene id: 1324350:AOY20_RS03775
uniprot id: A0A0N9VCB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1324350:AOY20 RS09050
gene id: 1324350:AOY20_RS09050
uniprot id: A0A0N9VQL0
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

1324350:AOY20 RS07355
gene id: 1324350:AOY20_RS07355
uniprot id: A0A0N9VPT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1324350:AOY20 RS05315
gene id: 1324350:AOY20_RS05315
uniprot id: A0A0N7GXK9
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1324350:AOY20 RS13485
gene id: 1324350:AOY20_RS13485
uniprot id: A0A0N9VAT7
names: Similarity
messages: Belongs to the Gfa family.

1324350:AOY20 RS01665
gene id: 1324350:AOY20_RS01665
uniprot id: A0A0N9VAT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1324350:AOY20 RS05395
gene id: 1324350:AOY20_RS05395
uniprot id: A0A0N7GXL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1324350:AOY20 RS09575
gene id: 1324350:AOY20_RS09575
uniprot id: A0A0N9W2G2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1324350:AOY20 RS02965
gene id: 1324350:AOY20_RS02965
uniprot id: A0A0N9VWX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1324350:AOY20 RS08485
gene id: 1324350:AOY20_RS08485
uniprot id: A0A0N9VWK2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1324350:AOY20 RS00345
gene id: 1324350:AOY20_RS00345
uniprot id: A0A0N9VSD1
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS03810
gene id: 1324350:AOY20_RS03810
uniprot id: A0A0N9VBT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS00565
gene id: 1324350:AOY20_RS00565
uniprot id: A0A0N9VAW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1324350:AOY20 RS03065
gene id: 1324350:AOY20_RS03065
uniprot id: A0A0N9V5T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS02760
gene id: 1324350:AOY20_RS02760
uniprot id: A0A0N9VZ61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1324350:AOY20 RS01750
gene id: 1324350:AOY20_RS01750
uniprot id: A0A0N9WAI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1324350:AOY20 RS13545
gene id: 1324350:AOY20_RS13545
uniprot id: A0A0N9W5E5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1324350:AOY20 RS13410
gene id: 1324350:AOY20_RS13410
uniprot id: A0A0N9WG42
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1324350:AOY20 RS01355
gene id: 1324350:AOY20_RS01355
uniprot id: A0A0N9VAM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1324350:AOY20 RS10910
gene id: 1324350:AOY20_RS10910
uniprot id: A0A0N9W0E1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1324350:AOY20 RS01690
gene id: 1324350:AOY20_RS01690
uniprot id: A0A0N9WAH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1324350:AOY20 RS02415
gene id: 1324350:AOY20_RS02415
uniprot id: A0A0N9W0E9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1324350:AOY20 RS07890
gene id: 1324350:AOY20_RS07890
uniprot id: A0A0N9VE82
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1324350:AOY20 RS04485
gene id: 1324350:AOY20_RS04485
uniprot id: A0A0N9W1F4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1324350:AOY20 RS00550
gene id: 1324350:AOY20_RS00550
uniprot id: A0A0N9VY06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1324350:AOY20 RS10495
gene id: 1324350:AOY20_RS10495
uniprot id: A0A0N9VXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1324350:AOY20 RS04815
gene id: 1324350:AOY20_RS04815
uniprot id: A0A0N9VUU9
names: Similarity
messages: Belongs to the RecJ family.

1324350:AOY20 RS12200
gene id: 1324350:AOY20_RS12200
uniprot id: A0A0N9VS82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1324350:AOY20 RS01115
gene id: 1324350:AOY20_RS01115
uniprot id: A0A0N9WA48
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1324350:AOY20 RS11500
gene id: 1324350:AOY20_RS11500
uniprot id: A0A0N7GXZ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1324350:AOY20 RS02900
gene id: 1324350:AOY20_RS02900
uniprot id: A0A0N9VWW5
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1324350:AOY20 RS03380
gene id: 1324350:AOY20_RS03380
uniprot id: A0A0N9VZF5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

1324350:AOY20 RS00805
gene id: 1324350:AOY20_RS00805
uniprot id: A0A0N9VY48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1324350:AOY20 RS07980
gene id: 1324350:AOY20_RS07980
uniprot id: A0A0N9VQ59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS03640
gene id: 1324350:AOY20_RS03640
uniprot id: A0A0N9VZJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1324350:AOY20 RS07365
gene id: 1324350:AOY20_RS07365
uniprot id: A0A0N9VDJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1324350:AOY20 RS08315
gene id: 1324350:AOY20_RS08315
uniprot id: A0A0N9VDW8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1324350:AOY20 RS05505
gene id: 1324350:AOY20_RS05505
uniprot id: A0A0N9VCS4
names: Similarity
messages: Belongs to the GSP E family.

1324350:AOY20 RS01755
gene id: 1324350:AOY20_RS01755
uniprot id: A0A0N9VBD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS03240
gene id: 1324350:AOY20_RS03240
uniprot id: A0A0N9VBH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1324350:AOY20 RS09065
gene id: 1324350:AOY20_RS09065
uniprot id: A0A0N7GXU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1324350:AOY20 RS12015
gene id: 1324350:AOY20_RS12015
uniprot id: A0A0N9VXV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1324350:AOY20 RS11700
gene id: 1324350:AOY20_RS11700
uniprot id: A0A0N9W4P6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1324350:AOY20 RS07395
gene id: 1324350:AOY20_RS07395
uniprot id: A0A0N9W2Z6
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS03635
gene id: 1324350:AOY20_RS03635
uniprot id: A0A0N9VBQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1324350:AOY20 RS05400
gene id: 1324350:AOY20_RS05400
uniprot id: A0A0N9VD33
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1324350:AOY20 RS11450
gene id: 1324350:AOY20_RS11450
uniprot id: A0A0N7GXZ6
names: Similarity
messages: Belongs to the PrpD family.

1324350:AOY20 RS13860
gene id: 1324350:AOY20_RS13860
uniprot id: A0A0N9W5I2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1324350:AOY20 RS03695
gene id: 1324350:AOY20_RS03695
uniprot id: A0A0N7GXH2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1324350:AOY20 RS13135
gene id: 1324350:AOY20_RS13135
uniprot id: A0A0N9VYA0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1324350:AOY20 RS04840
gene id: 1324350:AOY20_RS04840
uniprot id: A0A0N9W018
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1324350:AOY20 RS00460
gene id: 1324350:AOY20_RS00460
uniprot id: A0A0N7GXA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1324350:AOY20 RS10195
gene id: 1324350:AOY20_RS10195
uniprot id: A0A0N9VX90
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1324350:AOY20 RS04415
gene id: 1324350:AOY20_RS04415
uniprot id: A0A0N9WBR5
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS07680
gene id: 1324350:AOY20_RS07680
uniprot id: A0A0N9V8E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1324350:AOY20 RS10785
gene id: 1324350:AOY20_RS10785
uniprot id: A0A0N9VEU6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1324350:AOY20 RS05345
gene id: 1324350:AOY20_RS05345
uniprot id: A0A0N9W1W2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1324350:AOY20 RS02970
gene id: 1324350:AOY20_RS02970
uniprot id: A0A0N9VBD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1324350:AOY20 RS10750
gene id: 1324350:AOY20_RS10750
uniprot id: A0A0N9W4B4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS13065
gene id: 1324350:AOY20_RS13065
uniprot id: A0A0N9VAK9
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1324350:AOY20 RS12650
gene id: 1324350:AOY20_RS12650
uniprot id: A0A0N9W124
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1324350:AOY20 RS03980
gene id: 1324350:AOY20_RS03980
uniprot id: A0A0N9W164
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS11995
gene id: 1324350:AOY20_RS11995
uniprot id: A0A0N9WFI1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1324350:AOY20 RS00125
gene id: 1324350:AOY20_RS00125
uniprot id: A0A0N9W9H5
names: Subcellular Location Annotation
messages: Cell surface

1324350:AOY20 RS09700
gene id: 1324350:AOY20_RS09700
uniprot id: A0A0N9W5X8
names: Subunit
messages: Monomer.

1324350:AOY20 RS08015
gene id: 1324350:AOY20_RS08015
uniprot id: A0A0N9VEA2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS03800
gene id: 1324350:AOY20_RS03800
uniprot id: A0A0N9VMW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1324350:AOY20 RS11475
gene id: 1324350:AOY20_RS11475
uniprot id: A0A0N9W4N9
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS08840
gene id: 1324350:AOY20_RS08840
uniprot id: A0A0N9WE73
names: Similarity
messages: Belongs to the TelA family.

1324350:AOY20 RS05945
gene id: 1324350:AOY20_RS05945
uniprot id: A0A0N9VCZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1324350:AOY20 RS02945
gene id: 1324350:AOY20_RS02945
uniprot id: A0A0N9V5R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1324350:AOY20 RS10530
gene id: 1324350:AOY20_RS10530
uniprot id: A0A0N9WEY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1324350:AOY20 RS02505
gene id: 1324350:AOY20_RS02505
uniprot id: A0A0N9VB63
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS06410
gene id: 1324350:AOY20_RS06410
uniprot id: A0A0N9W106
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS10905
gene id: 1324350:AOY20_RS10905
uniprot id: A0A0N9W5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1324350:AOY20 RS13415
gene id: 1324350:AOY20_RS13415
uniprot id: A0A0N7GY41
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS11040
gene id: 1324350:AOY20_RS11040
uniprot id: A0A0N9W321
names: Similarity
messages: Belongs to the peptidase M1 family.

1324350:AOY20 RS01675
gene id: 1324350:AOY20_RS01675
uniprot id: A0A0N9VYI5
names: Similarity
messages: Belongs to the peptidase S41A family.

1324350:AOY20 RS06290
gene id: 1324350:AOY20_RS06290
uniprot id: A0A0N9VD29
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1324350:AOY20 RS04970
gene id: 1324350:AOY20_RS04970
uniprot id: A0A0N7GXK1
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS12210
gene id: 1324350:AOY20_RS12210
uniprot id: A0A0N9VFE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1324350:AOY20 RS00710
gene id: 1324350:AOY20_RS00710
uniprot id: A0A0N9V4M7
names: Similarity
messages: Belongs to the peptidase C59 family.

1324350:AOY20 RS08600
gene id: 1324350:AOY20_RS08600
uniprot id: A0A0N9VEI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1324350:AOY20 RS00340
gene id: 1324350:AOY20_RS00340
uniprot id: A0A0N9V4G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1324350:AOY20 RS11785
gene id: 1324350:AOY20_RS11785
uniprot id: A0A0N9VT25
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1324350:AOY20 RS01515
gene id: 1324350:AOY20_RS01515
uniprot id: A0A0N7GXC4
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1324350:AOY20 RS02275
gene id: 1324350:AOY20_RS02275
uniprot id: A0A0N9VYU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1324350:AOY20 RS08535
gene id: 1324350:AOY20_RS08535
uniprot id: A0A0N9VT09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1324350:AOY20 RS03300
gene id: 1324350:AOY20_RS03300
uniprot id: A0A0N9VMN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1324350:AOY20 RS14075
gene id: 1324350:AOY20_RS14075
uniprot id: A0A0N9W490
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1324350:AOY20 RS09970
gene id: 1324350:AOY20_RS09970
uniprot id: A0A0N9VZZ0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1324350:AOY20 RS13705
gene id: 1324350:AOY20_RS13705
uniprot id: A0A0N9W3S9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS01320
gene id: 1324350:AOY20_RS01320
uniprot id: A0A0N9VB64
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1324350:AOY20 RS05420
gene id: 1324350:AOY20_RS05420
uniprot id: A0A0N9V736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS07670
gene id: 1324350:AOY20_RS07670
uniprot id: A0A0N9VE56
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1324350:AOY20 RS06795
gene id: 1324350:AOY20_RS06795
uniprot id: A0A0N9VVU3
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS13885
gene id: 1324350:AOY20_RS13885
uniprot id: A0A0N9VG37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1324350:AOY20 RS04160
gene id: 1324350:AOY20_RS04160
uniprot id: A0A0N7GXI2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS11110
gene id: 1324350:AOY20_RS11110
uniprot id: A0A0N9W2S1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1324350:AOY20 RS07490
gene id: 1324350:AOY20_RS07490
uniprot id: A0A0N9VDL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1324350:AOY20 RS09855
gene id: 1324350:AOY20_RS09855
uniprot id: A0A0N9W2J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1324350:AOY20 RS05585
gene id: 1324350:AOY20_RS05585
uniprot id: A0A0N9VCT5
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS05195
gene id: 1324350:AOY20_RS05195
uniprot id: A0A0N7GXK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1324350:AOY20 RS11920
gene id: 1324350:AOY20_RS11920
uniprot id: A0A0N9W3D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1324350:AOY20 RS05060
gene id: 1324350:AOY20_RS05060
uniprot id: A0A0N7GXK3
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1324350:AOY20 RS02270
gene id: 1324350:AOY20_RS02270
uniprot id: A0A0N9VYX5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1324350:AOY20 RS11440
gene id: 1324350:AOY20_RS11440
uniprot id: A0A0N9VXN8
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS06900
gene id: 1324350:AOY20_RS06900
uniprot id: A0A0N9VDR6
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1324350:AOY20 RS07655
gene id: 1324350:AOY20_RS07655
uniprot id: A0A0N9W1I6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1324350:AOY20 RS09725
gene id: 1324350:AOY20_RS09725
uniprot id: A0A0N9W3X8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1324350:AOY20 RS06990
gene id: 1324350:AOY20_RS06990
uniprot id: A0A0N9VPL6
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1324350:AOY20 RS14880
gene id: 1324350:AOY20_RS14880
uniprot id: A0A0N9VXL6
names: Subcellular Location Annotation
messages: Cell surface

1324350:AOY20 RS11570
gene id: 1324350:AOY20_RS11570
uniprot id: A0A0N9VFL6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1324350:AOY20 RS12035
gene id: 1324350:AOY20_RS12035
uniprot id: A0A0N9VFB4
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1324350:AOY20 RS13375
gene id: 1324350:AOY20_RS13375
uniprot id: A0A0N7GY40
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1324350:AOY20 RS12175
gene id: 1324350:AOY20_RS12175
uniprot id: A0A0N9VFU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1324350:AOY20 RS06505
gene id: 1324350:AOY20_RS06505
uniprot id: A0A0N9W2I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS02040
gene id: 1324350:AOY20_RS02040
uniprot id: A0A0N7GXD6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1324350:AOY20 RS06385
gene id: 1324350:AOY20_RS06385
uniprot id: A0A0N9VVN6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1324350:AOY20 RS03755
gene id: 1324350:AOY20_RS03755
uniprot id: A0A0N9VBS8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1324350:AOY20 RS08560
gene id: 1324350:AOY20_RS08560
uniprot id: A0A0N9VWL2
names: Similarity
messages: Belongs to the peptidase S16 family.

1324350:AOY20 RS09585
gene id: 1324350:AOY20_RS09585
uniprot id: A0A0N9WEK4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1324350:AOY20 RS10080
gene id: 1324350:AOY20_RS10080
uniprot id: A0A0N9VR72
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1324350:AOY20 RS04005
gene id: 1324350:AOY20_RS04005
uniprot id: A0A0N7GXH9
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS13205
gene id: 1324350:AOY20_RS13205
uniprot id: A0A0N7GY36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1324350:AOY20 RS12380
gene id: 1324350:AOY20_RS12380
uniprot id: A0A0N9VAA3
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1324350:AOY20 RS09385
gene id: 1324350:AOY20_RS09385
uniprot id: A0A0N9VEB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1324350:AOY20 RS06905
gene id: 1324350:AOY20_RS06905
uniprot id: A0A0N7GXP4
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS02595
gene id: 1324350:AOY20_RS02595
uniprot id: A0A0N9VBR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1324350:AOY20 RS08920
gene id: 1324350:AOY20_RS08920
uniprot id: A0A0N9V8X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1324350:AOY20 RS07125
gene id: 1324350:AOY20_RS07125
uniprot id: A0A0N7GXP9
names: Function
messages: Involved in the transposition of the insertion sequence.

1324350:AOY20 RS11470
gene id: 1324350:AOY20_RS11470
uniprot id: A0A0N9W2W9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1324350:AOY20 RS12710
gene id: 1324350:AOY20_RS12710
uniprot id: A0A0N9W129
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1324350:AOY20 RS07910
gene id: 1324350:AOY20_RS07910
uniprot id: A0A0N9VQ48
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS12600
gene id: 1324350:AOY20_RS12600
uniprot id: A0A0N9VG10
names: Similarity
messages: Belongs to the asparaginase 1 family.

1324350:AOY20 RS04285
gene id: 1324350:AOY20_RS04285
uniprot id: A0A0N7GXI5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1324350:AOY20 RS10330
gene id: 1324350:AOY20_RS10330
uniprot id: A0A0N9VEN8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1324350:AOY20 RS08940
gene id: 1324350:AOY20_RS08940
uniprot id: A0A0N7GXT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1324350:AOY20 RS04255
gene id: 1324350:AOY20_RS04255
uniprot id: A0A0N9V6D7
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1324350:AOY20 RS02975
gene id: 1324350:AOY20_RS02975
uniprot id: A0A0N9VZ90
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1324350:AOY20 RS06165
gene id: 1324350:AOY20_RS06165
uniprot id: A0A0N9VD14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1324350:AOY20 RS05925
gene id: 1324350:AOY20_RS05925
uniprot id: A0A0N9VVF5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1324350:AOY20 RS12850
gene id: 1324350:AOY20_RS12850
uniprot id: A0A0N9W3F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1324350:AOY20 RS04810
gene id: 1324350:AOY20_RS04810
uniprot id: A0A0N9V6R6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS13540
gene id: 1324350:AOY20_RS13540
uniprot id: A0A0N7GY44
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1324350:AOY20 RS14135
gene id: 1324350:AOY20_RS14135
uniprot id: A0A0N9W1L0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1324350:AOY20 RS06175
gene id: 1324350:AOY20_RS06175
uniprot id: A0A0N9W0R1
names: Similarity
messages: Belongs to the YciI family.

1324350:AOY20 RS07290
gene id: 1324350:AOY20_RS07290
uniprot id: A0A0N9VW45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS07975
gene id: 1324350:AOY20_RS07975
uniprot id: A0A0N9VWE5
names: Similarity
messages: Belongs to the YkuD family.

1324350:AOY20 RS11675
gene id: 1324350:AOY20_RS11675
uniprot id: A0A0N9W398
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1324350:AOY20 RS01770
gene id: 1324350:AOY20_RS01770
uniprot id: A0A0N7GXD0
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1324350:AOY20 RS13965
gene id: 1324350:AOY20_RS13965
uniprot id: A0A0N9WGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1324350:AOY20 RS00360
gene id: 1324350:AOY20_RS00360
uniprot id: A0A0N9VA46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1324350:AOY20 RS05290
gene id: 1324350:AOY20_RS05290
uniprot id: A0A0N9W1U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1324350:AOY20 RS08320
gene id: 1324350:AOY20_RS08320
uniprot id: A0A0N9W206
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1324350:AOY20 RS04730
gene id: 1324350:AOY20_RS04730
uniprot id: A0A0N9WBY7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1324350:AOY20 RS01550
gene id: 1324350:AOY20_RS01550
uniprot id: A0A0N9VYH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1324350:AOY20 RS00765
gene id: 1324350:AOY20_RS00765
uniprot id: A0A0N9VZJ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1324350:AOY20 RS13180
gene id: 1324350:AOY20_RS13180
uniprot id: A0A0N9W595
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS03115
gene id: 1324350:AOY20_RS03115
uniprot id: A0A0N9W0R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1324350:AOY20 RS14185
gene id: 1324350:AOY20_RS14185
uniprot id: A0A0N9VSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS04035
gene id: 1324350:AOY20_RS04035
uniprot id: A0A0N9W173
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1324350:AOY20 RS14360
gene id: 1324350:AOY20_RS14360
uniprot id: A0A0N9VG95
names: Subcellular Location Annotation
messages: Cell surface

1324350:AOY20 RS03290
gene id: 1324350:AOY20_RS03290
uniprot id: A0A0N9VU03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1324350:AOY20 RS05725
gene id: 1324350:AOY20_RS05725
uniprot id: A0A0N9W5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS07150
gene id: 1324350:AOY20_RS07150
uniprot id: A0A0N9WDH4
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1324350:AOY20 RS09785
gene id: 1324350:AOY20_RS09785
uniprot id: A0A0N9VEF8
names: Similarity
messages: Belongs to the Gfa family.

1324350:AOY20 RS10150
gene id: 1324350:AOY20_RS10150
uniprot id: A0A0N9VEK9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1324350:AOY20 RS02880
gene id: 1324350:AOY20_RS02880
uniprot id: A0A0N9VGS9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1324350:AOY20 RS05480
gene id: 1324350:AOY20_RS05480
uniprot id: A0A0N9V750
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1324350:AOY20 RS07080
gene id: 1324350:AOY20_RS07080
uniprot id: A0A0N7GXP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1324350:AOY20 RS09710
gene id: 1324350:AOY20_RS09710
uniprot id: A0A0N9W279
names: Similarity
messages: Belongs to the fabD family.

1324350:AOY20 RS11445
gene id: 1324350:AOY20_RS11445
uniprot id: A0A0N9VRW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS07750
gene id: 1324350:AOY20_RS07750
uniprot id: A0A0N9VQ35
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS04210
gene id: 1324350:AOY20_RS04210
uniprot id: A0A0N9VXH7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1324350:AOY20 RS02265
gene id: 1324350:AOY20_RS02265
uniprot id: A0A0N9VB22
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1324350:AOY20 RS03975
gene id: 1324350:AOY20_RS03975
uniprot id: A0A0N9VCE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS13070
gene id: 1324350:AOY20_RS13070
uniprot id: A0A0N9VY86
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1324350:AOY20 RS09865
gene id: 1324350:AOY20_RS09865
uniprot id: A0A0N9WEP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1324350:AOY20 RS05090
gene id: 1324350:AOY20_RS05090
uniprot id: A0A0N9WC70
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1324350:AOY20 RS01640
gene id: 1324350:AOY20_RS01640
uniprot id: A0A0N7GXC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1324350:AOY20 RS04235
gene id: 1324350:AOY20_RS04235
uniprot id: A0A0N9WBM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1324350:AOY20 RS06515
gene id: 1324350:AOY20_RS06515
uniprot id: A0A0N9VVQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS02260
gene id: 1324350:AOY20_RS02260
uniprot id: A0A0N9VWL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1324350:AOY20 RS06680
gene id: 1324350:AOY20_RS06680
uniprot id: A0A0N9V7U6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1324350:AOY20 RS07495
gene id: 1324350:AOY20_RS07495
uniprot id: A0A0N9W1L4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1324350:AOY20 RS03235
gene id: 1324350:AOY20_RS03235
uniprot id: A0A0N9VX13
names: Similarity
messages: Belongs to the DprA/Smf family.

1324350:AOY20 RS14180
gene id: 1324350:AOY20_RS14180
uniprot id: A0A0N9VYN2
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS08755
gene id: 1324350:AOY20_RS08755
uniprot id: A0A0N9VQF6
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1324350:AOY20 RS08375
gene id: 1324350:AOY20_RS08375
uniprot id: A0A0N7GXS6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1324350:AOY20 RS10155
gene id: 1324350:AOY20_RS10155
uniprot id: A0A0N9W2P3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1324350:AOY20 RS02465
gene id: 1324350:AOY20_RS02465
uniprot id: A0A0N9VBP5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1324350:AOY20 RS05205
gene id: 1324350:AOY20_RS05205
uniprot id: A0A0N9VCK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1324350:AOY20 RS14165
gene id: 1324350:AOY20_RS14165
uniprot id: A0A0N9VGN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS10390
gene id: 1324350:AOY20_RS10390
uniprot id: A0A0N9VEP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1324350:AOY20 RS11835
gene id: 1324350:AOY20_RS11835
uniprot id: A0A0N9VXT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1324350:AOY20 RS02355
gene id: 1324350:AOY20_RS02355
uniprot id: A0A0N9V5G8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1324350:AOY20 RS02980
gene id: 1324350:AOY20_RS02980
uniprot id: A0A0N9VZ66
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1324350:AOY20 RS09965
gene id: 1324350:AOY20_RS09965
uniprot id: A0A0N9VR46
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1324350:AOY20 RS05200
gene id: 1324350:AOY20_RS05200
uniprot id: A0A0N9VXX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1324350:AOY20 RS08220
gene id: 1324350:AOY20_RS08220
uniprot id: A0A0N9W3B7
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS00855
gene id: 1324350:AOY20_RS00855
uniprot id: A0A0N7GXA9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1324350:AOY20 RS10835
gene id: 1324350:AOY20_RS10835
uniprot id: A0A0N9W0D2
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1324350:AOY20 RS05910
gene id: 1324350:AOY20_RS05910
uniprot id: A0A0N9VDB7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1324350:AOY20 RS07545
gene id: 1324350:AOY20_RS07545
uniprot id: A0A0N9V8C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1324350:AOY20 RS04340
gene id: 1324350:AOY20_RS04340
uniprot id: A0A0N9VC37
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1324350:AOY20 RS09870
gene id: 1324350:AOY20_RS09870
uniprot id: A0A0N9VEY5
names: Similarity
messages: Belongs to the GARS family.

1324350:AOY20 RS13425
gene id: 1324350:AOY20_RS13425
uniprot id: A0A0N9W5D0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1324350:AOY20 RS11125
gene id: 1324350:AOY20_RS11125
uniprot id: A0A0N9VFE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1324350:AOY20 RS14065
gene id: 1324350:AOY20_RS14065
uniprot id: A0A0N9W1K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS03225
gene id: 1324350:AOY20_RS03225
uniprot id: A0A0N9VTZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1324350:AOY20 RS13335
gene id: 1324350:AOY20_RS13335
uniprot id: A0A0N9VFU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1324350:AOY20 RS02240
gene id: 1324350:AOY20_RS02240
uniprot id: A0A0N9V5E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1324350:AOY20 RS12155
gene id: 1324350:AOY20_RS12155
uniprot id: A0A0N7GY12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1324350:AOY20 RS07455
gene id: 1324350:AOY20_RS07455
uniprot id: A0A0N9VE15
names: Similarity
messages: Belongs to the YjdM family.

1324350:AOY20 RS11875
gene id: 1324350:AOY20_RS11875
uniprot id: A0A0N9VFQ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1324350:AOY20 RS11790
gene id: 1324350:AOY20_RS11790
uniprot id: A0A0N9W0R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS13680
gene id: 1324350:AOY20_RS13680
uniprot id: A0A0N9VYG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1324350:AOY20 RS00750
gene id: 1324350:AOY20_RS00750
uniprot id: A0A0N9VXZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1324350:AOY20 RS12580
gene id: 1324350:AOY20_RS12580
uniprot id: A0A0N7GY22
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1324350:AOY20 RS14285
gene id: 1324350:AOY20_RS14285
uniprot id: A0A0N7GX91
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS01785
gene id: 1324350:AOY20_RS01785
uniprot id: A0A0N9VWD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1324350:AOY20 RS08460
gene id: 1324350:AOY20_RS08460
uniprot id: A0A0N9WE20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS09560
gene id: 1324350:AOY20_RS09560
uniprot id: A0A0N9VQX9
names: Similarity
messages: Belongs to the peptidase M24B family.

1324350:AOY20 RS13870
gene id: 1324350:AOY20_RS13870
uniprot id: A0A0N9VYJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1324350:AOY20 RS05270
gene id: 1324350:AOY20_RS05270
uniprot id: A0A0N9W096
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS04040
gene id: 1324350:AOY20_RS04040
uniprot id: A0A0N9V6A7
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS07540
gene id: 1324350:AOY20_RS07540
uniprot id: A0A0N9W337
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1324350:AOY20 RS11015
gene id: 1324350:AOY20_RS11015
uniprot id: A0A0N9VXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1324350:AOY20 RS05260
gene id: 1324350:AOY20_RS05260
uniprot id: A0A0N9VCL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS14250
gene id: 1324350:AOY20_RS14250
uniprot id: A0A0N7GY60
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1324350:AOY20 RS13125
gene id: 1324350:AOY20_RS13125
uniprot id: A0A0N9W588
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1324350:AOY20 RS10450
gene id: 1324350:AOY20_RS10450
uniprot id: A0A0N9VEQ3
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1324350:AOY20 RS12415
gene id: 1324350:AOY20_RS12415
uniprot id: A0A0N7GY18
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS01220
gene id: 1324350:AOY20_RS01220
uniprot id: A0A0N9V4V8
names: Similarity
messages: Belongs to the MlaA family.

1324350:AOY20 RS09300
gene id: 1324350:AOY20_RS09300
uniprot id: A0A0N9VQP2
names: Similarity
messages: Belongs to the peptidase C40 family.

1324350:AOY20 RS11730
gene id: 1324350:AOY20_RS11730
uniprot id: A0A0N7GY02
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1324350:AOY20 RS07550
gene id: 1324350:AOY20_RS07550
uniprot id: A0A0N9VWA1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1324350:AOY20 RS01285
gene id: 1324350:AOY20_RS01285
uniprot id: A0A0N9VLN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1324350:AOY20 RS11345
gene id: 1324350:AOY20_RS11345
uniprot id: A0A0N9W360
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1324350:AOY20 RS00490
gene id: 1324350:AOY20_RS00490
uniprot id: A0A0N9VXW0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1324350:AOY20 RS11090
gene id: 1324350:AOY20_RS11090
uniprot id: A0A0N9W0H2
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS06595
gene id: 1324350:AOY20_RS06595
uniprot id: A0A0N9W140
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS04475
gene id: 1324350:AOY20_RS04475
uniprot id: A0A0N9WBT4
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1324350:AOY20 RS10815
gene id: 1324350:AOY20_RS10815
uniprot id: A0A0N9W4B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1324350:AOY20 RS13765
gene id: 1324350:AOY20_RS13765
uniprot id: A0A0N9W1G4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1324350:AOY20 RS07020
gene id: 1324350:AOY20_RS07020
uniprot id: A0A0N9WDB7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1324350:AOY20 RS08395
gene id: 1324350:AOY20_RS08395
uniprot id: A0A0N9W1Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1324350:AOY20 RS10200
gene id: 1324350:AOY20_RS10200
uniprot id: A0A0N9VR88
names: Similarity
messages: Belongs to the PhzF family.

1324350:AOY20 RS07025
gene id: 1324350:AOY20_RS07025
uniprot id: A0A0N9VDU4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1324350:AOY20 RS07725
gene id: 1324350:AOY20_RS07725
uniprot id: A0A0N9VE65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1324350:AOY20 RS03665
gene id: 1324350:AOY20_RS03665
uniprot id: A0A0N9W107
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS12970
gene id: 1324350:AOY20_RS12970
uniprot id: A0A0N9W152
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1324350:AOY20 RS01345
gene id: 1324350:AOY20_RS01345
uniprot id: A0A0N9VLQ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1324350:AOY20 RS04605
gene id: 1324350:AOY20_RS04605
uniprot id: A0A0N9W1H4
names: Similarity
messages: Belongs to the allantoicase family.

1324350:AOY20 RS03920
gene id: 1324350:AOY20_RS03920
uniprot id: A0A0N9W153
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1324350:AOY20 RS01465
gene id: 1324350:AOY20_RS01465
uniprot id: A0A0N9VSZ3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1324350:AOY20 RS05415
gene id: 1324350:AOY20_RS05415
uniprot id: A0A0N9WGM3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1324350:AOY20 RS05210
gene id: 1324350:AOY20_RS05210
uniprot id: A0A0N9W0B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1324350:AOY20 RS09610
gene id: 1324350:AOY20_RS09610
uniprot id: A0A0N9VX18
names: Similarity
messages: Belongs to the UPF0102 family.

1324350:AOY20 RS05745
gene id: 1324350:AOY20_RS05745
uniprot id: A0A0N9VVB7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1324350:AOY20 RS06830
gene id: 1324350:AOY20_RS06830
uniprot id: A0A0N9W126
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1324350:AOY20 RS03700
gene id: 1324350:AOY20_RS03700
uniprot id: A0A0N9VZK8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1324350:AOY20 RS04780
gene id: 1324350:AOY20_RS04780
uniprot id: A0A0N9W005
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1324350:AOY20 RS06610
gene id: 1324350:AOY20_RS06610
uniprot id: A0A0N9WD29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS12080
gene id: 1324350:AOY20_RS12080
uniprot id: A0A0N9VS59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1324350:AOY20 RS12490
gene id: 1324350:AOY20_RS12490
uniprot id: A0A0N9W509
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1324350:AOY20 RS01310
gene id: 1324350:AOY20_RS01310
uniprot id: A0A0N9VYB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1324350:AOY20 RS08785
gene id: 1324350:AOY20_RS08785
uniprot id: A0A0N9WE59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1324350:AOY20 RS13975
gene id: 1324350:AOY20_RS13975
uniprot id: A0A0N7GY54
names: Similarity
messages: Belongs to the UPF0178 family.

1324350:AOY20 RS12665
gene id: 1324350:AOY20_RS12665
uniprot id: A0A0N9W3C4
names: Similarity
messages: Belongs to the universal stress protein A family.

1324350:AOY20 RS00240
gene id: 1324350:AOY20_RS00240
uniprot id: A0A0N9VA18
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1324350:AOY20 RS08090
gene id: 1324350:AOY20_RS08090
uniprot id: A0A0N9V8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1324350:AOY20 RS02045
gene id: 1324350:AOY20_RS02045
uniprot id: A0A0N9VWI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1324350:AOY20 RS12365
gene id: 1324350:AOY20_RS12365
uniprot id: A0A0N9VFX9
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

1324350:AOY20 RS00870
gene id: 1324350:AOY20_RS00870
uniprot id: A0A0N9VGA2
names: Similarity
messages: Belongs to the UPF0145 family.

1324350:AOY20 RS02640
gene id: 1324350:AOY20_RS02640
uniprot id: A0A0N9VZ37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1324350:AOY20 RS02435
gene id: 1324350:AOY20_RS02435
uniprot id: A0A0N9VWQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1324350:AOY20 RS11045
gene id: 1324350:AOY20_RS11045
uniprot id: A0A0N9W2R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1324350:AOY20 RS05715
gene id: 1324350:AOY20_RS05715
uniprot id: A0A0N7GXL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1324350:AOY20 RS06240
gene id: 1324350:AOY20_RS06240
uniprot id: A0A0N9W0S1
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1324350:AOY20 RS02090
gene id: 1324350:AOY20_RS02090
uniprot id: A0A0N9V5C3
names: Similarity
messages: Belongs to the Gfa family.

1324350:AOY20 RS05325
gene id: 1324350:AOY20_RS05325
uniprot id: A0A0N9W0E6
names: Similarity
messages: Belongs to the RutC family.

1324350:AOY20 RS11285
gene id: 1324350:AOY20_RS11285
uniprot id: A0A0N9W347
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1324350:AOY20 RS03165
gene id: 1324350:AOY20_RS03165
uniprot id: A0A0N9VYS6
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS08025
gene id: 1324350:AOY20_RS08025
uniprot id: A0A0N9V8K0
names: Similarity
messages: Belongs to the VgrG protein family.

1324350:AOY20 RS00780
gene id: 1324350:AOY20_RS00780
uniprot id: A0A0N9VSL6
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS07235
gene id: 1324350:AOY20_RS07235
uniprot id: A0A0N9VW21
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1324350:AOY20 RS10830
gene id: 1324350:AOY20_RS10830
uniprot id: A0A0N9VRJ7
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS02495
gene id: 1324350:AOY20_RS02495
uniprot id: A0A0N7GXE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1324350:AOY20 RS10490
gene id: 1324350:AOY20_RS10490
uniprot id: A0A0N9V9H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1324350:AOY20 RS11690
gene id: 1324350:AOY20_RS11690
uniprot id: A0A0N7GY01
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS07330
gene id: 1324350:AOY20_RS07330
uniprot id: A0A0N9VDY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS04385
gene id: 1324350:AOY20_RS04385
uniprot id: A0A0N9VN69
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1324350:AOY20 RS03215
gene id: 1324350:AOY20_RS03215
uniprot id: A0A0N9W0T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS04980
gene id: 1324350:AOY20_RS04980
uniprot id: A0A0N9W1P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1324350:AOY20 RS03850
gene id: 1324350:AOY20_RS03850
uniprot id: A0A0N9VUD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1324350:AOY20 RS03970
gene id: 1324350:AOY20_RS03970
uniprot id: A0A0N9WBJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1324350:AOY20 RS13025
gene id: 1324350:AOY20_RS13025
uniprot id: A0A0N9W160
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS11855
gene id: 1324350:AOY20_RS11855
uniprot id: A0A0N9W3C6
names: Similarity
messages: Belongs to the nitroreductase family.

1324350:AOY20 RS11735
gene id: 1324350:AOY20_RS11735
uniprot id: A0A0N9W3A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1324350:AOY20 RS10420
gene id: 1324350:AOY20_RS10420
uniprot id: A0A0N9W467
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1324350:AOY20 RS11650
gene id: 1324350:AOY20_RS11650
uniprot id: A0A0N9VXR3
names: Similarity
messages: Belongs to the glutamate synthase family.

1324350:AOY20 RS02335
gene id: 1324350:AOY20_RS02335
uniprot id: A0A0N9VYV4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1324350:AOY20 RS01430
gene id: 1324350:AOY20_RS01430
uniprot id: A0A0N9VYG3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1324350:AOY20 RS08215
gene id: 1324350:AOY20_RS08215
uniprot id: A0A0N9VEC5
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS03305
gene id: 1324350:AOY20_RS03305
uniprot id: A0A0N9VX24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1324350:AOY20 RS11615
gene id: 1324350:AOY20_RS11615
uniprot id: A0A0N9W391
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1324350:AOY20 RS05960
gene id: 1324350:AOY20_RS05960
uniprot id: A0A0N9WCP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS01180
gene id: 1324350:AOY20_RS01180
uniprot id: A0A0N9VB45
names: Similarity
messages: Belongs to the BolA/IbaG family.

1324350:AOY20 RS11350
gene id: 1324350:AOY20_RS11350
uniprot id: A0A0N9VGH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

1324350:AOY20 RS11050
gene id: 1324350:AOY20_RS11050
uniprot id: A0A0N9WF55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1324350:AOY20 RS05550
gene id: 1324350:AOY20_RS05550
uniprot id: A0A0N9VD55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1324350:AOY20 RS01480
gene id: 1324350:AOY20_RS01480
uniprot id: A0A0N9VW88
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS02800
gene id: 1324350:AOY20_RS02800
uniprot id: A0A0N7GXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1324350:AOY20 RS02345
gene id: 1324350:AOY20_RS02345
uniprot id: A0A0N9VBM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1324350:AOY20 RS01685
gene id: 1324350:AOY20_RS01685
uniprot id: A0A0N9VB65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1324350:AOY20 RS03280
gene id: 1324350:AOY20_RS03280
uniprot id: A0A0N9W0U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1324350:AOY20 RS13945
gene id: 1324350:AOY20_RS13945
uniprot id: A0A0N9W1I4
names: Similarity
messages: Belongs to the peptidase S49 family.

1324350:AOY20 RS11165
gene id: 1324350:AOY20_RS11165
uniprot id: A0A0N9W333
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1324350:AOY20 RS13865
gene id: 1324350:AOY20_RS13865
uniprot id: A0A0N9VAZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1324350:AOY20 RS14040
gene id: 1324350:AOY20_RS14040
uniprot id: A0A0N9W5K4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1324350:AOY20 RS00685
gene id: 1324350:AOY20_RS00685
uniprot id: A0A0N7GXA5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS07755
gene id: 1324350:AOY20_RS07755
uniprot id: A0A0N9VZ47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS01340
gene id: 1324350:AOY20_RS01340
uniprot id: A0A0N9VSX1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1324350:AOY20 RS08965
gene id: 1324350:AOY20_RS08965
uniprot id: A0A0N9VEM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1324350:AOY20 RS13315
gene id: 1324350:AOY20_RS13315
uniprot id: A0A0N9VYC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1324350:AOY20 RS01530
gene id: 1324350:AOY20_RS01530
uniprot id: A0A0N9VT04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1324350:AOY20 RS05760
gene id: 1324350:AOY20_RS05760
uniprot id: A0A0N7GXL9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1324350:AOY20 RS02235
gene id: 1324350:AOY20_RS02235
uniprot id: A0A0N9W0B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1324350:AOY20 RS07485
gene id: 1324350:AOY20_RS07485
uniprot id: A0A0N9VYZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1324350:AOY20 RS10075
gene id: 1324350:AOY20_RS10075
uniprot id: A0A0N9VX72
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1324350:AOY20 RS08510
gene id: 1324350:AOY20_RS08510
uniprot id: A0A0N9VBA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS06255
gene id: 1324350:AOY20_RS06255
uniprot id: A0A0N9VDH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1324350:AOY20 RS06965
gene id: 1324350:AOY20_RS06965
uniprot id: A0A0N9VDS7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1324350:AOY20 RS09505
gene id: 1324350:AOY20_RS09505
uniprot id: A0A0N9VEC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1324350:AOY20 RS04375
gene id: 1324350:AOY20_RS04375
uniprot id: A0A0N9V6H0
names: Similarity
messages: Belongs to the UPF0260 family.

1324350:AOY20 RS04760
gene id: 1324350:AOY20_RS04760
uniprot id: A0A0N7GXJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1324350:AOY20 RS06050
gene id: 1324350:AOY20_RS06050
uniprot id: A0A0N9W284
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1324350:AOY20 RS00055
gene id: 1324350:AOY20_RS00055
uniprot id: A0A0N7GX91
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS11580
gene id: 1324350:AOY20_RS11580
uniprot id: A0A0N9V9V8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1324350:AOY20 RS13570
gene id: 1324350:AOY20_RS13570
uniprot id: A0A0N9W4Q7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1324350:AOY20 RS00955
gene id: 1324350:AOY20_RS00955
uniprot id: A0A0N9V4R9
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS11490
gene id: 1324350:AOY20_RS11490
uniprot id: A0A0N9W4M4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1324350:AOY20 RS01610
gene id: 1324350:AOY20_RS01610
uniprot id: A0A0N9VAT0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1324350:AOY20 RS10255
gene id: 1324350:AOY20_RS10255
uniprot id: A0A0N9VRA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1324350:AOY20 RS07650
gene id: 1324350:AOY20_RS07650
uniprot id: A0A0N9W1R7
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1324350:AOY20 RS12255
gene id: 1324350:AOY20_RS12255
uniprot id: A0A0N9VS96
names: Similarity
messages: Belongs to the UPF0053 family.

1324350:AOY20 RS03655
gene id: 1324350:AOY20_RS03655
uniprot id: A0A0N7GXH1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1324350:AOY20 RS13985
gene id: 1324350:AOY20_RS13985
uniprot id: A0A0N9VB04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS00210
gene id: 1324350:AOY20_RS00210
uniprot id: A0A0N7GX94
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1324350:AOY20 RS06195
gene id: 1324350:AOY20_RS06195
uniprot id: A0A0N9W2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1324350:AOY20 RS07255
gene id: 1324350:AOY20_RS07255
uniprot id: A0A0N7GXQ2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1324350:AOY20 RS12400
gene id: 1324350:AOY20_RS12400
uniprot id: A0A0N9VFH0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1324350:AOY20 RS08470
gene id: 1324350:AOY20_RS08470
uniprot id: A0A0N9W5W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS13645
gene id: 1324350:AOY20_RS13645
uniprot id: A0A0N9W440
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1324350:AOY20 RS07880
gene id: 1324350:AOY20_RS07880
uniprot id: A0A0N9W1K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

1324350:AOY20 RS03690
gene id: 1324350:AOY20_RS03690
uniprot id: A0A0N9VBR5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1324350:AOY20 RS13265
gene id: 1324350:AOY20_RS13265
uniprot id: A0A0N9W195
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1324350:AOY20 RS05880
gene id: 1324350:AOY20_RS05880
uniprot id: A0A0N9VCY2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1324350:AOY20 RS00155
gene id: 1324350:AOY20_RS00155
uniprot id: A0A0N9VL53
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS12775
gene id: 1324350:AOY20_RS12775
uniprot id: A0A0N9W133
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1324350:AOY20 RS07050
gene id: 1324350:AOY20_RS07050
uniprot id: A0A0N9VPN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1324350:AOY20 RS06620
gene id: 1324350:AOY20_RS06620
uniprot id: A0A0N9W2L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1324350:AOY20 RS04755
gene id: 1324350:AOY20_RS04755
uniprot id: A0A0N9VNE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1324350:AOY20 RS00655
gene id: 1324350:AOY20_RS00655
uniprot id: A0A0N9V4L5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS13325
gene id: 1324350:AOY20_RS13325
uniprot id: A0A0N9W1A2
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1324350:AOY20 RS12515
gene id: 1324350:AOY20_RS12515
uniprot id: A0A0N9W109
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1324350:AOY20 RS05905
gene id: 1324350:AOY20_RS05905
uniprot id: A0A0N9WCN2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1324350:AOY20 RS14190
gene id: 1324350:AOY20_RS14190
uniprot id: A0A0N9W1Q1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1324350:AOY20 RS01930
gene id: 1324350:AOY20_RS01930
uniprot id: A0A0N9WAM0
names: Similarity
names: Subunit
messages: Belongs to the LigB/MhpB extradiol dioxygenase family.
messages: Homotetramer.

1324350:AOY20 RS12040
gene id: 1324350:AOY20_RS12040
uniprot id: A0A0N9W3F1
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1324350:AOY20 RS14170
gene id: 1324350:AOY20_RS14170
uniprot id: A0A0N9W5N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1324350:AOY20 RS14210
gene id: 1324350:AOY20_RS14210
uniprot id: A0A0N9W412
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1324350:AOY20 RS12520
gene id: 1324350:AOY20_RS12520
uniprot id: A0A0N9VFI7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1324350:AOY20 RS02875
gene id: 1324350:AOY20_RS02875
uniprot id: A0A0N9V5Q3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1324350:AOY20 RS09795
gene id: 1324350:AOY20_RS09795
uniprot id: A0A0N9W286
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1324350:AOY20 RS14265
gene id: 1324350:AOY20_RS14265
uniprot id: A0A0N9V9Z3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS07940
gene id: 1324350:AOY20_RS07940
uniprot id: A0A0N9WDU8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1324350:AOY20 RS03875
gene id: 1324350:AOY20_RS03875
uniprot id: A0A0N9VZN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
messages: Membrane

1324350:AOY20 RS00390
gene id: 1324350:AOY20_RS00390
uniprot id: A0A0N9VZD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1324350:AOY20 RS05340
gene id: 1324350:AOY20_RS05340
uniprot id: A0A0N9VD20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1324350:AOY20 RS02250
gene id: 1324350:AOY20_RS02250
uniprot id: A0A0N9VTD9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1324350:AOY20 RS07195
gene id: 1324350:AOY20_RS07195
uniprot id: A0A0N9VRT2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1324350:AOY20 RS02035
gene id: 1324350:AOY20_RS02035
uniprot id: A0A0N9VM25
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS13635
gene id: 1324350:AOY20_RS13635
uniprot id: A0A0N9W1E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1324350:AOY20 RS05185
gene id: 1324350:AOY20_RS05185
uniprot id: A0A0N9VV13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1324350:AOY20 RS01435
gene id: 1324350:AOY20_RS01435
uniprot id: A0A0N9VYE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1324350:AOY20 RS13300
gene id: 1324350:AOY20_RS13300
uniprot id: A0A0N9VGA0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS13615
gene id: 1324350:AOY20_RS13615
uniprot id: A0A0N9VAV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1324350:AOY20 RS01780
gene id: 1324350:AOY20_RS01780
uniprot id: A0A0N9VLY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS06260
gene id: 1324350:AOY20_RS06260
uniprot id: A0A0N9W2C3
names: Similarity
messages: Belongs to the hyi family.

1324350:AOY20 RS02360
gene id: 1324350:AOY20_RS02360
uniprot id: A0A0N9VTG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1324350:AOY20 RS10880
gene id: 1324350:AOY20_RS10880
uniprot id: A0A0N9W4C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS07400
gene id: 1324350:AOY20_RS07400
uniprot id: A0A0N9V889
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1324350:AOY20 RS06930
gene id: 1324350:AOY20_RS06930
uniprot id: A0A0N9VYQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1324350:AOY20 RS00795
gene id: 1324350:AOY20_RS00795
uniprot id: A0A0N9VVY2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1324350:AOY20 RS01175
gene id: 1324350:AOY20_RS01175
uniprot id: A0A0N9WA58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS12450
gene id: 1324350:AOY20_RS12450
uniprot id: A0A0N9VSC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS13595
gene id: 1324350:AOY20_RS13595
uniprot id: A0A0N9WG71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS03985
gene id: 1324350:AOY20_RS03985
uniprot id: A0A0N9V696
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1324350:AOY20 RS10610
gene id: 1324350:AOY20_RS10610
uniprot id: A0A0N9WEZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1324350:AOY20 RS08780
gene id: 1324350:AOY20_RS08780
uniprot id: A0A0N9W1V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1324350:AOY20 RS03680
gene id: 1324350:AOY20_RS03680
uniprot id: A0A0N9VMT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1324350:AOY20 RS13730
gene id: 1324350:AOY20_RS13730
uniprot id: A0A0N7GY78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1324350:AOY20 RS12090
gene id: 1324350:AOY20_RS12090
uniprot id: A0A0N9VFC4
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS06825
gene id: 1324350:AOY20_RS06825
uniprot id: A0A0N9W179
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS13130
gene id: 1324350:AOY20_RS13130
uniprot id: A0A0N9VAL7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1324350:AOY20 RS13075
gene id: 1324350:AOY20_RS13075
uniprot id: A0A0N7GY33
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS00470
gene id: 1324350:AOY20_RS00470
uniprot id: A0A0N9VLA2
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1324350:AOY20 RS04445
gene id: 1324350:AOY20_RS04445
uniprot id: A0A0N9VXL3
names: Similarity
messages: Belongs to the catalase family.

1324350:AOY20 RS04425
gene id: 1324350:AOY20_RS04425
uniprot id: A0A0N9W1D9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1324350:AOY20 RS06955
gene id: 1324350:AOY20_RS06955
uniprot id: A0A0N9W147
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1324350:AOY20 RS12030
gene id: 1324350:AOY20_RS12030
uniprot id: A0A0N7GY09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1324350:AOY20 RS03055
gene id: 1324350:AOY20_RS03055
uniprot id: A0A0N9VBZ1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1324350:AOY20 RS08850
gene id: 1324350:AOY20_RS08850
uniprot id: A0A0N9W3L8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1324350:AOY20 RS07795
gene id: 1324350:AOY20_RS07795
uniprot id: A0A0N9V8I2
names: Subcellular Location Annotation
messages: Cell inner membrane

1324350:AOY20 RS06405
gene id: 1324350:AOY20_RS06405
uniprot id: A0A0N9VD46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1324350:AOY20 RS04915
gene id: 1324350:AOY20_RS04915
uniprot id: A0A0N9W1N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1324350:AOY20 RS04300
gene id: 1324350:AOY20_RS04300
uniprot id: A0A0N9VCJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1324350:AOY20 RS06650
gene id: 1324350:AOY20_RS06650
uniprot id: A0A0N9VD76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1324350:AOY20 RS10970
gene id: 1324350:AOY20_RS10970
uniprot id: A0A0N9VEX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1324350:AOY20 RS05055
gene id: 1324350:AOY20_RS05055
uniprot id: A0A0N9VUZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1324350:AOY20 RS02305
gene id: 1324350:AOY20_RS02305
uniprot id: A0A0N9VTF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1324350:AOY20 RS00980
gene id: 1324350:AOY20_RS00980
uniprot id: A0A0N7GXB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS04110
gene id: 1324350:AOY20_RS04110
uniprot id: A0A0N9VN22
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1324350:AOY20 RS02860
gene id: 1324350:AOY20_RS02860
uniprot id: A0A0N9VBV8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1324350:AOY20 RS11420
gene id: 1324350:AOY20_RS11420
uniprot id: A0A0N9WF95
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1324350:AOY20 RS04790
gene id: 1324350:AOY20_RS04790
uniprot id: A0A0N9VCT6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1324350:AOY20 RS04850
gene id: 1324350:AOY20_RS04850
uniprot id: A0A0N9WC17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1324350:AOY20 RS01570
gene id: 1324350:AOY20_RS01570
uniprot id: A0A0N9VBA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1324350:AOY20 RS09890
gene id: 1324350:AOY20_RS09890
uniprot id: A0A0N9VX50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1324350:AOY20 RS11435
gene id: 1324350:AOY20_RS11435
uniprot id: A0A0N9V9U0
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1324350:AOY20 RS11805
gene id: 1324350:AOY20_RS11805
uniprot id: A0A0N9W312
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1324350:AOY20 RS01245
gene id: 1324350:AOY20_RS01245
uniprot id: A0A0N9VYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1324350:AOY20 RS09645
gene id: 1324350:AOY20_RS09645
uniprot id: A0A0N9WGQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1324350:AOY20 RS06805
gene id: 1324350:AOY20_RS06805
uniprot id: A0A0N9W4I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1324350:AOY20 RS05545
gene id: 1324350:AOY20_RS05545
uniprot id: A0A0N9WCF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1324350:AOY20 RS08480
gene id: 1324350:AOY20_RS08480
uniprot id: A0A0N9V8Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS11495
gene id: 1324350:AOY20_RS11495
uniprot id: A0A0N7GY75
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1324350:AOY20 RS13405
gene id: 1324350:AOY20_RS13405
uniprot id: A0A0N9W3N8
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS01130
gene id: 1324350:AOY20_RS01130
uniprot id: A0A0N9V4V1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS13475
gene id: 1324350:AOY20_RS13475
uniprot id: A0A0N9VGC2
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS06995
gene id: 1324350:AOY20_RS06995
uniprot id: A0A0N7GXP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1324350:AOY20 RS06460
gene id: 1324350:AOY20_RS06460
uniprot id: A0A0N9VPB5
names: Similarity
messages: Belongs to the stealth family.

1324350:AOY20 RS07165
gene id: 1324350:AOY20_RS07165
uniprot id: A0A0N9V822
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS08855
gene id: 1324350:AOY20_RS08855
uniprot id: A0A0N7GXT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1324350:AOY20 RS04100
gene id: 1324350:AOY20_RS04100
uniprot id: A0A0N9V6B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1324350:AOY20 RS04925
gene id: 1324350:AOY20_RS04925
uniprot id: A0A0N9W461
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1324350:AOY20 RS00365
gene id: 1324350:AOY20_RS00365
uniprot id: A0A0N9VXX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1324350:AOY20 RS07575
gene id: 1324350:AOY20_RS07575
uniprot id: A0A0N9W1P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1324350:AOY20 RS12235
gene id: 1324350:AOY20_RS12235
uniprot id: A0A0N7GY14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1324350:AOY20 RS06775
gene id: 1324350:AOY20_RS06775
uniprot id: A0A0N7GXP1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1324350:AOY20 RS05155
gene id: 1324350:AOY20_RS05155
uniprot id: A0A0N9W077
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1324350:AOY20 RS10795
gene id: 1324350:AOY20_RS10795
uniprot id: A0A0N9W2N1
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1324350:AOY20 RS11480
gene id: 1324350:AOY20_RS11480
uniprot id: A0A0N9W2W9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1324350:AOY20 RS03950
gene id: 1324350:AOY20_RS03950
uniprot id: A0A0N9VBW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1324350:AOY20 RS10380
gene id: 1324350:AOY20_RS10380
uniprot id: A0A0N9VRC0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1324350:AOY20 RS05915
gene id: 1324350:AOY20_RS05915
uniprot id: A0A0N9W259
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1324350:AOY20 RS13775
gene id: 1324350:AOY20_RS13775
uniprot id: A0A0N9VG19
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1324350:AOY20 RS03010
gene id: 1324350:AOY20_RS03010
uniprot id: A0A0N9V5S2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1324350:AOY20 RS01100
gene id: 1324350:AOY20_RS01100
uniprot id: A0A0N9VY97
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1324350:AOY20 RS07160
gene id: 1324350:AOY20_RS07160
uniprot id: A0A0N9W2V3
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS09675
gene id: 1324350:AOY20_RS09675
uniprot id: A0A0N9VR04
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1324350:AOY20 RS13280
gene id: 1324350:AOY20_RS13280
uniprot id: A0A0N9W3M1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS05015
gene id: 1324350:AOY20_RS05015
uniprot id: A0A0N7GXK2
names: Similarity
messages: Belongs to the SurE nucleotidase family.

1324350:AOY20 RS04065
gene id: 1324350:AOY20_RS04065
uniprot id: A0A0N9VBY2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1324350:AOY20 RS06425
gene id: 1324350:AOY20_RS06425
uniprot id: A0A0N9VDJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1324350:AOY20 RS07380
gene id: 1324350:AOY20_RS07380
uniprot id: A0A0N9W1D6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1324350:AOY20 RS03080
gene id: 1324350:AOY20_RS03080
uniprot id: A0A0N9VWZ9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1324350:AOY20 RS02000
gene id: 1324350:AOY20_RS02000
uniprot id: A0A0N9W090
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1324350:AOY20 RS01300
gene id: 1324350:AOY20_RS01300
uniprot id: A0A0N9VAL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1324350:AOY20 RS00220
gene id: 1324350:AOY20_RS00220
uniprot id: A0A0N9V4E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1324350:AOY20 RS07215
gene id: 1324350:AOY20_RS07215
uniprot id: A0A0N9VDW9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1324350:AOY20 RS05170
gene id: 1324350:AOY20_RS05170
uniprot id: A0A0N9W1S5
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS13905
gene id: 1324350:AOY20_RS13905
uniprot id: A0A0N9VH23
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1324350:AOY20 RS09395
gene id: 1324350:AOY20_RS09395
uniprot id: A0A0N9W233
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1324350:AOY20 RS11830
gene id: 1324350:AOY20_RS11830
uniprot id: A0A0N9VA21
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1324350:AOY20 RS02925
gene id: 1324350:AOY20_RS02925
uniprot id: A0A0N9VZ56
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1324350:AOY20 RS02940
gene id: 1324350:AOY20_RS02940
uniprot id: A0A0N9W0N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1324350:AOY20 RS08445
gene id: 1324350:AOY20_RS08445
uniprot id: A0A0N9W220
names: Similarity
messages: Belongs to the group II decarboxylase family.

1324350:AOY20 RS08340
gene id: 1324350:AOY20_RS08340
uniprot id: A0A0N9WDY9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1324350:AOY20 RS10460
gene id: 1324350:AOY20_RS10460
uniprot id: A0A0N9W4L7
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1324350:AOY20 RS11265
gene id: 1324350:AOY20_RS11265
uniprot id: A0A0N9VRT2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1324350:AOY20 RS08475
gene id: 1324350:AOY20_RS08475
uniprot id: A0A0N9W3G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS00480
gene id: 1324350:AOY20_RS00480
uniprot id: A0A0N9VA61
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1324350:AOY20 RS01620
gene id: 1324350:AOY20_RS01620
uniprot id: A0A0N9VYH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1324350:AOY20 RS03135
gene id: 1324350:AOY20_RS03135
uniprot id: A0A0N9VML1
names: Similarity
messages: Belongs to the UPF0053 family.

1324350:AOY20 RS02400
gene id: 1324350:AOY20_RS02400
uniprot id: A0A0N9VBN8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1324350:AOY20 RS11525
gene id: 1324350:AOY20_RS11525
uniprot id: A0A0N9W0N1
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1324350:AOY20 RS04805
gene id: 1324350:AOY20_RS04805
uniprot id: A0A0N7GXJ7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1324350:AOY20 RS13465
gene id: 1324350:AOY20_RS13465
uniprot id: A0A0N9W3P8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1324350:AOY20 RS05385
gene id: 1324350:AOY20_RS05385
uniprot id: A0A0N9W0B6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1324350:AOY20 RS04455
gene id: 1324350:AOY20_RS04455
uniprot id: A0A0N9VYT5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1324350:AOY20 RS01015
gene id: 1324350:AOY20_RS01015
uniprot id: A0A0N9VSR3
names: Similarity
messages: Belongs to the transposase 8 family.

1324350:AOY20 RS05660
gene id: 1324350:AOY20_RS05660
uniprot id: A0A0N9WCI0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1324350:AOY20 RS05590
gene id: 1324350:AOY20_RS05590
uniprot id: A0A0N9W0J3
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS01955
gene id: 1324350:AOY20_RS01955
uniprot id: A0A0N9VT96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS04360
gene id: 1324350:AOY20_RS04360
uniprot id: A0A0N9VCL1
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1324350:AOY20 RS10825
gene id: 1324350:AOY20_RS10825
uniprot id: A0A0N9VXH0
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1324350:AOY20 RS03160
gene id: 1324350:AOY20_RS03160
uniprot id: A0A0N9VZ94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1324350:AOY20 RS05095
gene id: 1324350:AOY20_RS05095
uniprot id: A0A0N9VCY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1324350:AOY20 RS00075
gene id: 1324350:AOY20_RS00075
uniprot id: A0A0N9VZ80
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1324350:AOY20 RS11595
gene id: 1324350:AOY20_RS11595
uniprot id: A0A0N9VRY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1324350:AOY20 RS11925
gene id: 1324350:AOY20_RS11925
uniprot id: A0A0N9W326
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1324350:AOY20 RS03855
gene id: 1324350:AOY20_RS03855
uniprot id: A0A0N9VMX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1324350:AOY20 RS13160
gene id: 1324350:AOY20_RS13160
uniprot id: A0A0N7GY35
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1324350:AOY20 RS02340
gene id: 1324350:AOY20_RS02340
uniprot id: A0A0N9WAV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1324350:AOY20 RS03070
gene id: 1324350:AOY20_RS03070
uniprot id: A0A0N9VTW2
names: Similarity
messages: Belongs to the P(II) protein family.

1324350:AOY20 RS02790
gene id: 1324350:AOY20_RS02790
uniprot id: A0A0N9VTR1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS01525
gene id: 1324350:AOY20_RS01525
uniprot id: A0A0N9V528
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS10745
gene id: 1324350:AOY20_RS10745
uniprot id: A0A0N9VFA3
names: Similarity
messages: Belongs to the MQO family.

1324350:AOY20 RS06985
gene id: 1324350:AOY20_RS06985
uniprot id: A0A0N9VVX5
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1324350:AOY20 RS00320
gene id: 1324350:AOY20_RS00320
uniprot id: A0A0N9W9L5
names: Subcellular Location Annotation
messages: Cytoplasm

1324350:AOY20 RS10190
gene id: 1324350:AOY20_RS10190
uniprot id: A0A0N9V9C7
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1324350:AOY20 RS00840
gene id: 1324350:AOY20_RS00840
uniprot id: A0A0N9VSN1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1324350:AOY20 RS01505
gene id: 1324350:AOY20_RS01505
uniprot id: A0A0N9WAC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1324350:AOY20 RS06645
gene id: 1324350:AOY20_RS06645
uniprot id: A0A0N7GXN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1324350:AOY20 RS04200
gene id: 1324350:AOY20_RS04200
uniprot id: A0A0N7GXI3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1324350:AOY20 RS13925
gene id: 1324350:AOY20_RS13925
uniprot id: A0A0N9VB00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1324350:AOY20 RS00595
gene id: 1324350:AOY20_RS00595
uniprot id: A0A0N9VLC1
names: Similarity
messages: Belongs to the citrate synthase family.

1324350:AOY20 RS12135
gene id: 1324350:AOY20_RS12135
uniprot id: A0A0N9VS70
names: Similarity
messages: Belongs to the HSP15 family.

1324350:AOY20 RS07190
gene id: 1324350:AOY20_RS07190
uniprot id: A0A0N9VDG9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1324350:AOY20 RS04975
gene id: 1324350:AOY20_RS04975
uniprot id: A0A0N9VCW8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1324350:AOY20 RS06270
gene id: 1324350:AOY20_RS06270
uniprot id: A0A0N7GXN0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1324350:AOY20 RS02310
gene id: 1324350:AOY20_RS02310
uniprot id: A0A0N9VM66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1324350:AOY20 RS15035
gene id: 1324350:AOY20_RS15035
uniprot id: A0A0N9W185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS02515
gene id: 1324350:AOY20_RS02515
uniprot id: A0A0N9VYY6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1324350:AOY20 RS12405
gene id: 1324350:AOY20_RS12405
uniprot id: A0A0N9W3J7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS13590
gene id: 1324350:AOY20_RS13590
uniprot id: A0A0N9W3R3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1324350:AOY20 RS14000
gene id: 1324350:AOY20_RS14000
uniprot id: A0A0N9W1J5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS01265
gene id: 1324350:AOY20_RS01265
uniprot id: A0A0N9VB55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1324350:AOY20 RS04015
gene id: 1324350:AOY20_RS04015
uniprot id: A0A0N9VZR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1324350:AOY20 RS02350
gene id: 1324350:AOY20_RS02350
uniprot id: A0A0N9W0D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1324350:AOY20 RS13720
gene id: 1324350:AOY20_RS13720
uniprot id: A0A0N9VGG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1324350:AOY20 RS01190
gene id: 1324350:AOY20_RS01190
uniprot id: A0A0N7GXB7
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1324350:AOY20 RS12350
gene id: 1324350:AOY20_RS12350
uniprot id: A0A0N9VGI1
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS00885
gene id: 1324350:AOY20_RS00885
uniprot id: A0A0N9VB06
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1324350:AOY20 RS10625
gene id: 1324350:AOY20_RS10625
uniprot id: A0A0N7GXX7
names: Similarity
messages: Belongs to the citrate synthase family.

1324350:AOY20 RS07730
gene id: 1324350:AOY20_RS07730
uniprot id: A0A0N9W355
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1324350:AOY20 RS08390
gene id: 1324350:AOY20_RS08390
uniprot id: A0A0N9W216
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1324350:AOY20 RS08815
gene id: 1324350:AOY20_RS08815
uniprot id: A0A0N7GXT6
names: Similarity
messages: Belongs to the peptidase S8 family.

1324350:AOY20 RS02775
gene id: 1324350:AOY20_RS02775
uniprot id: A0A0N9VBU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1324350:AOY20 RS13120
gene id: 1324350:AOY20_RS13120
uniprot id: A0A0N7GY34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1324350:AOY20 RS05460
gene id: 1324350:AOY20_RS05460
uniprot id: A0A0N9W0D6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1324350:AOY20 RS03150
gene id: 1324350:AOY20_RS03150
uniprot id: A0A0N9VZC1
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS04740
gene id: 1324350:AOY20_RS04740
uniprot id: A0A0N9W1J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1324350:AOY20 RS14030
gene id: 1324350:AOY20_RS14030
uniprot id: A0A0N9WGD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS04880
gene id: 1324350:AOY20_RS04880
uniprot id: A0A0N9VXS4
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS06670
gene id: 1324350:AOY20_RS06670
uniprot id: A0A0N9VDN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1324350:AOY20 RS12170
gene id: 1324350:AOY20_RS12170
uniprot id: A0A0N9WFK5
names: Similarity
messages: Belongs to the Skp family.

1324350:AOY20 RS06440
gene id: 1324350:AOY20_RS06440
uniprot id: A0A0N7GXN4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1324350:AOY20 RS13455
gene id: 1324350:AOY20_RS13455
uniprot id: A0A0N7GY42
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1324350:AOY20 RS12640
gene id: 1324350:AOY20_RS12640
uniprot id: A0A0N7GY23
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS09920
gene id: 1324350:AOY20_RS09920
uniprot id: A0A0N9W2A4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1324350:AOY20 RS05770
gene id: 1324350:AOY20_RS05770
uniprot id: A0A0N9W0M7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1324350:AOY20 RS13225
gene id: 1324350:AOY20_RS13225
uniprot id: A0A0N9W3L5
names: Function
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
messages: Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo.

1324350:AOY20 RS12145
gene id: 1324350:AOY20_RS12145
uniprot id: A0A0N9VFD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1324350:AOY20 RS13530
gene id: 1324350:AOY20_RS13530
uniprot id: A0A0N9WG62
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1324350:AOY20 RS06225
gene id: 1324350:AOY20_RS06225
uniprot id: A0A0N7GXM9
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS00350
gene id: 1324350:AOY20_RS00350
uniprot id: A0A0N9VL81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1324350:AOY20 RS07325
gene id: 1324350:AOY20_RS07325
uniprot id: A0A0N9WDM0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1324350:AOY20 RS04050
gene id: 1324350:AOY20_RS04050
uniprot id: A0A0N9VUG2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1324350:AOY20 RS05310
gene id: 1324350:AOY20_RS05310
uniprot id: A0A0N9VY03
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS04610
gene id: 1324350:AOY20_RS04610
uniprot id: A0A0N9V6N3
names: Similarity
messages: Belongs to the FAD-dependent urate hydroxylase family.

1324350:AOY20 RS07065
gene id: 1324350:AOY20_RS07065
uniprot id: A0A0N9W1C5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1324350:AOY20 RS08425
gene id: 1324350:AOY20_RS08425
uniprot id: A0A0N9VWJ2
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS02405
gene id: 1324350:AOY20_RS02405
uniprot id: A0A0N7GXE4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1324350:AOY20 RS06035
gene id: 1324350:AOY20_RS06035
uniprot id: A0A0N9WCR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1324350:AOY20 RS05675
gene id: 1324350:AOY20_RS05675
uniprot id: A0A0N7GXL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1324350:AOY20 RS08360
gene id: 1324350:AOY20_RS08360
uniprot id: A0A0N9VWI5
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1324350:AOY20 RS08285
gene id: 1324350:AOY20_RS08285
uniprot id: A0A0N9W3C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1324350:AOY20 RS03565
gene id: 1324350:AOY20_RS03565
uniprot id: A0A0N9VX63
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS07555
gene id: 1324350:AOY20_RS07555
uniprot id: A0A0N9VQ07
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1324350:AOY20 RS10735
gene id: 1324350:AOY20_RS10735
uniprot id: A0A0N9WF15
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1324350:AOY20 RS03570
gene id: 1324350:AOY20_RS03570
uniprot id: A0A0N7GXG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

1324350:AOY20 RS10465
gene id: 1324350:AOY20_RS10465
uniprot id: A0A0N9W2I3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1324350:AOY20 RS09495
gene id: 1324350:AOY20_RS09495
uniprot id: A0A0N9VQU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS06585
gene id: 1324350:AOY20_RS06585
uniprot id: A0A0N9VYK5
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1324350:AOY20 RS11825
gene id: 1324350:AOY20_RS11825
uniprot id: A0A0N9W4R4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1324350:AOY20 RS13675
gene id: 1324350:AOY20_RS13675
uniprot id: A0A0N9VAW6
names: Subunit
messages: Homodimer.

1324350:AOY20 RS08900
gene id: 1324350:AOY20_RS08900
uniprot id: A0A0N9WE76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1324350:AOY20 RS13020
gene id: 1324350:AOY20_RS13020
uniprot id: A0A0N9VSJ2
names: Similarity
messages: Belongs to the GST superfamily.

1324350:AOY20 RS10980
gene id: 1324350:AOY20_RS10980
uniprot id: A0A0N7GXY5
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

1324350:AOY20 RS12860
gene id: 1324350:AOY20_RS12860
uniprot id: A0A0N7GY28
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1324350:AOY20 RS06135
gene id: 1324350:AOY20_RS06135
uniprot id: A0A0N9W295
names: Similarity
messages: Belongs to the thioredoxin family.

1324350:AOY20 RS04930
gene id: 1324350:AOY20_RS04930
uniprot id: A0A0N7GXK0
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS06940
gene id: 1324350:AOY20_RS06940
uniprot id: A0A0N7GXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1324350:AOY20 RS13535
gene id: 1324350:AOY20_RS13535
uniprot id: A0A0N9VGD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1324350:AOY20 RS10790
gene id: 1324350:AOY20_RS10790
uniprot id: A0A0N9W2Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1324350:AOY20 RS02755
gene id: 1324350:AOY20_RS02755
uniprot id: A0A0N7GXF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1324350:AOY20 RS05595
gene id: 1324350:AOY20_RS05595
uniprot id: A0A0N7GXL5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS09840
gene id: 1324350:AOY20_RS09840
uniprot id: A0A0N9VBC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS10985
gene id: 1324350:AOY20_RS10985
uniprot id: A0A0N9W2Q4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1324350:AOY20 RS05470
gene id: 1324350:AOY20_RS05470
uniprot id: A0A0N9VD43
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1324350:AOY20 RS12720
gene id: 1324350:AOY20_RS12720
uniprot id: A0A0N9W3P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1324350:AOY20 RS11325
gene id: 1324350:AOY20_RS11325
uniprot id: A0A0N9VRU0
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS06315
gene id: 1324350:AOY20_RS06315
uniprot id: A0A0N9VDH9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1324350:AOY20 RS03315
gene id: 1324350:AOY20_RS03315
uniprot id: A0A0N9VZE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1324350:AOY20 RS12050
gene id: 1324350:AOY20_RS12050
uniprot id: A0A0N9WFJ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS08570
gene id: 1324350:AOY20_RS08570
uniprot id: A0A0N9VZF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1324350:AOY20 RS12810
gene id: 1324350:AOY20_RS12810
uniprot id: A0A0N9W548
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1324350:AOY20 RS05450
gene id: 1324350:AOY20_RS05450
uniprot id: A0A0N7GXL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1324350:AOY20 RS03330
gene id: 1324350:AOY20_RS03330
uniprot id: A0A0N9VC35
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1324350:AOY20 RS07350
gene id: 1324350:AOY20_RS07350
uniprot id: A0A0N9VW53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

1324350:AOY20 RS06780
gene id: 1324350:AOY20_RS06780
uniprot id: A0A0N9VDP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1324350:AOY20 RS03685
gene id: 1324350:AOY20_RS03685
uniprot id: A0A0N9VX83
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1324350:AOY20 RS13270
gene id: 1324350:AOY20_RS13270
uniprot id: A0A0N9VFU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1324350:AOY20 RS05335
gene id: 1324350:AOY20_RS05335
uniprot id: A0A0N9WCC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1324350:AOY20 RS07015
gene id: 1324350:AOY20_RS07015
uniprot id: A0A0N9W159
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1324350:AOY20 RS12915
gene id: 1324350:AOY20_RS12915
uniprot id: A0A0N7GY29
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS10870
gene id: 1324350:AOY20_RS10870
uniprot id: A0A0N9VFB8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1324350:AOY20 RS07780
gene id: 1324350:AOY20_RS07780
uniprot id: A0A0N9VE76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1324350:AOY20 RS00380
gene id: 1324350:AOY20_RS00380
uniprot id: A0A0N9W9N0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1324350:AOY20 RS13835
gene id: 1324350:AOY20_RS13835
uniprot id: A0A0N9W465
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1324350:AOY20 RS02735
gene id: 1324350:AOY20_RS02735
uniprot id: A0A0N9VTQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1324350:AOY20 RS12730
gene id: 1324350:AOY20_RS12730
uniprot id: A0A0N9W3D6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1324350:AOY20 RS11025
gene id: 1324350:AOY20_RS11025
uniprot id: A0A0N7GXY6
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1324350:AOY20 RS13220
gene id: 1324350:AOY20_RS13220
uniprot id: A0A0N9W3X7
names: Function
names: Similarity
messages: Belongs to the isochorismatase family. RutB subfamily.
messages: Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate. The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.

1324350:AOY20 RS13360
gene id: 1324350:AOY20_RS13360
uniprot id: A0A0N9W5C0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1324350:AOY20 RS00175
gene id: 1324350:AOY20_RS00175
uniprot id: A0A0N9VXP2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS02390
gene id: 1324350:AOY20_RS02390
uniprot id: A0A0N9VYW2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1324350:AOY20 RS02370
gene id: 1324350:AOY20_RS02370
uniprot id: A0A0N9VM80
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1324350:AOY20 RS05045
gene id: 1324350:AOY20_RS05045
uniprot id: A0A0N9W1Q3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1324350:AOY20 RS07030
gene id: 1324350:AOY20_RS07030
uniprot id: A0A0N9W2S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1324350:AOY20 RS01390
gene id: 1324350:AOY20_RS01390
uniprot id: A0A0N9VZX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1324350:AOY20 RS03120
gene id: 1324350:AOY20_RS03120
uniprot id: A0A0N9V5U5
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS00140
gene id: 1324350:AOY20_RS00140
uniprot id: A0A0N9V4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1324350:AOY20 RS03785
gene id: 1324350:AOY20_RS03785
uniprot id: A0A0N9W130
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1324350:AOY20 RS04070
gene id: 1324350:AOY20_RS04070
uniprot id: A0A0N9VZS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1324350:AOY20 RS04440
gene id: 1324350:AOY20_RS04440
uniprot id: A0A0N9VN79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS11600
gene id: 1324350:AOY20_RS11600
uniprot id: A0A0N9W0N8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1324350:AOY20 RS07525
gene id: 1324350:AOY20_RS07525
uniprot id: A0A0N7GXQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1324350:AOY20 RS13085
gene id: 1324350:AOY20_RS13085
uniprot id: A0A0N9W170
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

1324350:AOY20 RS02315
gene id: 1324350:AOY20_RS02315
uniprot id: A0A0N9VWN0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1324350:AOY20 RS01235
gene id: 1324350:AOY20_RS01235
uniprot id: A0A0N9VW56
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1324350:AOY20 RS03955
gene id: 1324350:AOY20_RS03955
uniprot id: A0A0N9VZQ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1324350:AOY20 RS08260
gene id: 1324350:AOY20_RS08260
uniprot id: A0A0N9W203
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1324350:AOY20 RS05940
gene id: 1324350:AOY20_RS05940
uniprot id: A0A0N9VYA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1324350:AOY20 RS00600
gene id: 1324350:AOY20_RS00600
uniprot id: A0A0N9VVU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1324350:AOY20 RS04525
gene id: 1324350:AOY20_RS04525
uniprot id: A0A0N9VZZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1324350:AOY20 RS08380
gene id: 1324350:AOY20_RS08380
uniprot id: A0A0N9VZC9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1324350:AOY20 RS05490
gene id: 1324350:AOY20_RS05490
uniprot id: A0A0N7GXL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1324350:AOY20 RS00465
gene id: 1324350:AOY20_RS00465
uniprot id: A0A0N9VSF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1324350:AOY20 RS12140
gene id: 1324350:AOY20_RS12140
uniprot id: A0A0N9W0W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1324350:AOY20 RS01475
gene id: 1324350:AOY20_RS01475
uniprot id: A0A0N9VLS1
names: Similarity
messages: Belongs to the YfgM family.

1324350:AOY20 RS12535
gene id: 1324350:AOY20_RS12535
uniprot id: A0A0N9WFQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1324350:AOY20 RS12395
gene id: 1324350:AOY20_RS12395
uniprot id: A0A0N9W0Z7
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS00625
gene id: 1324350:AOY20_RS00625
uniprot id: A0A0N9W9U2
names: Similarity
messages: Belongs to the peptidase M24B family.

1324350:AOY20 RS12020
gene id: 1324350:AOY20_RS12020
uniprot id: A0A0N9VS52
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1324350:AOY20 RS11455
gene id: 1324350:AOY20_RS11455
uniprot id: A0A0N9W0M5
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS01625
gene id: 1324350:AOY20_RS01625
uniprot id: A0A0N9WAF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1324350:AOY20 RS14010
gene id: 1324350:AOY20_RS14010
uniprot id: A0A0N9W487
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS05215
gene id: 1324350:AOY20_RS05215
uniprot id: A0A0N9W087
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS01740
gene id: 1324350:AOY20_RS01740
uniprot id: A0A0N9VYK4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1324350:AOY20 RS02920
gene id: 1324350:AOY20_RS02920
uniprot id: A0A0N7GXF5
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1324350:AOY20 RS10180
gene id: 1324350:AOY20_RS10180
uniprot id: A0A0N7GXW7
names: Similarity
messages: Belongs to the UPF0246 family.

1324350:AOY20 RS06005
gene id: 1324350:AOY20_RS06005
uniprot id: A0A0N9VYU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS11070
gene id: 1324350:AOY20_RS11070
uniprot id: A0A0N7GXY7
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1324350:AOY20 RS05125
gene id: 1324350:AOY20_RS05125
uniprot id: A0A0N9VV06
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1324350:AOY20 RS00485
gene id: 1324350:AOY20_RS00485
uniprot id: A0A0N9VXZ5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1324350:AOY20 RS05720
gene id: 1324350:AOY20_RS05720
uniprot id: A0A0N9WCJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1324350:AOY20 RS00415
gene id: 1324350:AOY20_RS00415
uniprot id: A0A0N7GX99
names: Similarity
messages: Belongs to the PrpF family.

1324350:AOY20 RS05150
gene id: 1324350:AOY20_RS05150
uniprot id: A0A0N7GXK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1324350:AOY20 RS12780
gene id: 1324350:AOY20_RS12780
uniprot id: A0A0N9VFM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS15015
gene id: 1324350:AOY20_RS15015
uniprot id: A0A0N9VSY2
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS11865
gene id: 1324350:AOY20_RS11865
uniprot id: A0A0N9W319
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1324350:AOY20 RS13305
gene id: 1324350:AOY20_RS13305
uniprot id: A0A0N9W5B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1324350:AOY20 RS06200
gene id: 1324350:AOY20_RS06200
uniprot id: A0A0N9V7I5
names: Similarity
messages: Belongs to the UPF0758 family.

1324350:AOY20 RS06530
gene id: 1324350:AOY20_RS06530
uniprot id: A0A0N9VYJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS11930
gene id: 1324350:AOY20_RS11930
uniprot id: A0A0N9WFH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1324350:AOY20 RS06640
gene id: 1324350:AOY20_RS06640
uniprot id: A0A0N9VYL5
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS07100
gene id: 1324350:AOY20_RS07100
uniprot id: A0A0N9W2U1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1324350:AOY20 RS08870
gene id: 1324350:AOY20_RS08870
uniprot id: A0A0N9VQH4
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS10925
gene id: 1324350:AOY20_RS10925
uniprot id: A0A0N9W2P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1324350:AOY20 RS00860
gene id: 1324350:AOY20_RS00860
uniprot id: A0A0N9VAC7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1324350:AOY20 RS01535
gene id: 1324350:AOY20_RS01535
uniprot id: A0A0N9VLS9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1324350:AOY20 RS02675
gene id: 1324350:AOY20_RS02675
uniprot id: A0A0N9VTN6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

1324350:AOY20 RS06370
gene id: 1324350:AOY20_RS06370
uniprot id: A0A0N9VDI4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1324350:AOY20 RS13930
gene id: 1324350:AOY20_RS13930
uniprot id: A0A0N9VYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1324350:AOY20 RS07090
gene id: 1324350:AOY20_RS07090
uniprot id: A0A0N9VB98
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1324350:AOY20 RS13095
gene id: 1324350:AOY20_RS13095
uniprot id: A0A0N9W3V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1324350:AOY20 RS07970
gene id: 1324350:AOY20_RS07970
uniprot id: A0A0N9V8J4
names: Similarity
messages: Belongs to the pirin family.

1324350:AOY20 RS00995
gene id: 1324350:AOY20_RS00995
uniprot id: A0A0N9WA24
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1324350:AOY20 RS11885
gene id: 1324350:AOY20_RS11885
uniprot id: A0A0N9VA40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1324350:AOY20 RS03020
gene id: 1324350:AOY20_RS03020
uniprot id: A0A0N9VMJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1324350:AOY20 RS14070
gene id: 1324350:AOY20_RS14070
uniprot id: A0A0N9VG64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1324350:AOY20 RS01070
gene id: 1324350:AOY20_RS01070
uniprot id: A0A0N9V4T9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1324350:AOY20 RS12890
gene id: 1324350:AOY20_RS12890
uniprot id: A0A0N9VSH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1324350:AOY20 RS11970
gene id: 1324350:AOY20_RS11970
uniprot id: A0A0N9W0U6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1324350:AOY20 RS01295
gene id: 1324350:AOY20_RS01295
uniprot id: A0A0N7GXB9
names: Similarity
messages: Belongs to the thioredoxin family.

1324350:AOY20 RS10885
gene id: 1324350:AOY20_RS10885
uniprot id: A0A0N9V9M3
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1324350:AOY20 RS13960
gene id: 1324350:AOY20_RS13960
uniprot id: A0A0N9W3W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1324350:AOY20 RS05560
gene id: 1324350:AOY20_RS05560
uniprot id: A0A0N9W1Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1324350:AOY20 RS00845
gene id: 1324350:AOY20_RS00845
uniprot id: A0A0N9VLG3
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS08500
gene id: 1324350:AOY20_RS08500
uniprot id: A0A0N7GXS9
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1324350:AOY20 RS01545
gene id: 1324350:AOY20_RS01545
uniprot id: A0A0N9VAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1324350:AOY20 RS12985
gene id: 1324350:AOY20_RS12985
uniprot id: A0A0N9W3H3
names: Subcellular Location Annotation
messages: Cytoplasm

1324350:AOY20 RS14305
gene id: 1324350:AOY20_RS14305
uniprot id: A0A0N9VZ80
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1324350:AOY20 RS00305
gene id: 1324350:AOY20_RS00305
uniprot id: A0A0N9VA33
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1324350:AOY20 RS01815
gene id: 1324350:AOY20_RS01815
uniprot id: A0A0N9VBF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1324350:AOY20 RS02430
gene id: 1324350:AOY20_RS02430
uniprot id: A0A0N9VM93
names: Similarity
messages: Belongs to the LOG family.

1324350:AOY20 RS10765
gene id: 1324350:AOY20_RS10765
uniprot id: A0A0N7GXY0
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1324350:AOY20 RS03320
gene id: 1324350:AOY20_RS03320
uniprot id: A0A0N9VZB8
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS00245
gene id: 1324350:AOY20_RS00245
uniprot id: A0A0N9VXV8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS04785
gene id: 1324350:AOY20_RS04785
uniprot id: A0A0N9WC04
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1324350:AOY20 RS10125
gene id: 1324350:AOY20_RS10125
uniprot id: A0A0N9V9B6
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1324350:AOY20 RS04290
gene id: 1324350:AOY20_RS04290
uniprot id: A0A0N9VZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1324350:AOY20 RS04960
gene id: 1324350:AOY20_RS04960
uniprot id: A0A0N9W046
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

1324350:AOY20 RS01440
gene id: 1324350:AOY20_RS01440
uniprot id: A0A0N9WAB4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1324350:AOY20 RS05830
gene id: 1324350:AOY20_RS05830
uniprot id: A0A0N9W0K2
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS00150
gene id: 1324350:AOY20_RS00150
uniprot id: A0A0N7GX93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1324350:AOY20 RS00570
gene id: 1324350:AOY20_RS00570
uniprot id: A0A0N7GY63
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1324350:AOY20 RS00695
gene id: 1324350:AOY20_RS00695
uniprot id: A0A0N9W9V4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1324350:AOY20 RS00375
gene id: 1324350:AOY20_RS00375
uniprot id: A0A0N7GX98
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1324350:AOY20 RS07135
gene id: 1324350:AOY20_RS07135
uniprot id: A0A0N9VDG1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS10840
gene id: 1324350:AOY20_RS10840
uniprot id: A0A0N9VEV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1324350:AOY20 RS01885
gene id: 1324350:AOY20_RS01885
uniprot id: A0A0N9V595
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1324350:AOY20 RS13140
gene id: 1324350:AOY20_RS13140
uniprot id: A0A0N9VSK1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS06915
gene id: 1324350:AOY20_RS06915
uniprot id: A0A0N9V7X9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1324350:AOY20 RS01840
gene id: 1324350:AOY20_RS01840
uniprot id: A0A0N9VLZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1324350:AOY20 RS09465
gene id: 1324350:AOY20_RS09465
uniprot id: A0A0N9WEI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1324350:AOY20 RS00660
gene id: 1324350:AOY20_RS00660
uniprot id: A0A0N9VSI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

1324350:AOY20 RS12700
gene id: 1324350:AOY20_RS12700
uniprot id: A0A0N9VY45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1324350:AOY20 RS10345
gene id: 1324350:AOY20_RS10345
uniprot id: A0A0N9VGG0
names: Similarity
messages: Belongs to the TPP enzyme family.

1324350:AOY20 RS07120
gene id: 1324350:AOY20_RS07120
uniprot id: A0A0N9VYT7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS13330
gene id: 1324350:AOY20_RS13330
uniprot id: A0A0N7GY39
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1324350:AOY20 RS08290
gene id: 1324350:AOY20_RS08290
uniprot id: A0A0N9V8N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1324350:AOY20 RS08975
gene id: 1324350:AOY20_RS08975
uniprot id: A0A0N9V8X6
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1324350:AOY20 RS12305
gene id: 1324350:AOY20_RS12305
uniprot id: A0A0N9VA99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1324350:AOY20 RS12315
gene id: 1324350:AOY20_RS12315
uniprot id: A0A0N9VSA6
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

1324350:AOY20 RS12465
gene id: 1324350:AOY20_RS12465
uniprot id: A0A0N9VFI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1324350:AOY20 RS07535
gene id: 1324350:AOY20_RS07535
uniprot id: A0A0N9VE41
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1324350:AOY20 RS06935
gene id: 1324350:AOY20_RS06935
uniprot id: A0A0N9WGN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1324350:AOY20 RS12835
gene id: 1324350:AOY20_RS12835
uniprot id: A0A0N9W138
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS05030
gene id: 1324350:AOY20_RS05030
uniprot id: A0A0N9W057
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1324350:AOY20 RS13690
gene id: 1324350:AOY20_RS13690
uniprot id: A0A0N9W1F6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1324350:AOY20 RS03650
gene id: 1324350:AOY20_RS03650
uniprot id: A0A0N9WBE1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1324350:AOY20 RS02695
gene id: 1324350:AOY20_RS02695
uniprot id: A0A0N9VZ49
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1324350:AOY20 RS11405
gene id: 1324350:AOY20_RS11405
uniprot id: A0A0N9W365
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1324350:AOY20 RS10900
gene id: 1324350:AOY20_RS10900
uniprot id: A0A0N9VRL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1324350:AOY20 RS13170
gene id: 1324350:AOY20_RS13170
uniprot id: A0A0N9WG04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1324350:AOY20 RS00330
gene id: 1324350:AOY20_RS00330
uniprot id: A0A0N9VZC3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1324350:AOY20 RS12605
gene id: 1324350:AOY20_RS12605
uniprot id: A0A0N9W525
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1324350:AOY20 RS05765
gene id: 1324350:AOY20_RS05765
uniprot id: A0A0N9VCX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS00250
gene id: 1324350:AOY20_RS00250
uniprot id: A0A0N7GX95
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1324350:AOY20 RS00650
gene id: 1324350:AOY20_RS00650
uniprot id: A0A0N9VZH4
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1324350:AOY20 RS10800
gene id: 1324350:AOY20_RS10800
uniprot id: A0A0N9WF26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1324350:AOY20 RS00430
gene id: 1324350:AOY20_RS00430
uniprot id: A0A0N9VXY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS05580
gene id: 1324350:AOY20_RS05580
uniprot id: A0A0N9VY44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS10695
gene id: 1324350:AOY20_RS10695
uniprot id: A0A0N9V9J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS03830
gene id: 1324350:AOY20_RS03830
uniprot id: A0A0N9WBH0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS03845
gene id: 1324350:AOY20_RS03845
uniprot id: A0A0N9V675
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1324350:AOY20 RS02930
gene id: 1324350:AOY20_RS02930
uniprot id: A0A0N9WB50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1324350:AOY20 RS01775
gene id: 1324350:AOY20_RS01775
uniprot id: A0A0N9VT54
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1324350:AOY20 RS06220
gene id: 1324350:AOY20_RS06220
uniprot id: A0A0N9VYE6
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1324350:AOY20 RS06025
gene id: 1324350:AOY20_RS06025
uniprot id: A0A0N7GXM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1324350:AOY20 RS00825
gene id: 1324350:AOY20_RS00825
uniprot id: A0A0N9VAZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1324350:AOY20 RS09510
gene id: 1324350:AOY20_RS09510
uniprot id: A0A0N7GXV2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1324350:AOY20 RS03025
gene id: 1324350:AOY20_RS03025
uniprot id: A0A0N9VWY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1324350:AOY20 RS03910
gene id: 1324350:AOY20_RS03910
uniprot id: A0A0N9WBI0
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1324350:AOY20 RS12385
gene id: 1324350:AOY20_RS12385
uniprot id: A0A0N9VY07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1324350:AOY20 RS04675
gene id: 1324350:AOY20_RS04675
uniprot id: A0A0N9V6P5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1324350:AOY20 RS10430
gene id: 1324350:AOY20_RS10430
uniprot id: A0A0N9VXB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1324350:AOY20 RS03265
gene id: 1324350:AOY20_RS03265
uniprot id: A0A0N9WB88
names: Similarity
messages: Belongs to the pirin family.

1324350:AOY20 RS12965
gene id: 1324350:AOY20_RS12965
uniprot id: A0A0N9VSI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1324350:AOY20 RS05080
gene id: 1324350:AOY20_RS05080
uniprot id: A0A0N9W085
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1324350:AOY20 RS04390
gene id: 1324350:AOY20_RS04390
uniprot id: A0A0N9VXK6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1324350:AOY20 RS02615
gene id: 1324350:AOY20_RS02615
uniprot id: A0A0N9VTM4
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS08255
gene id: 1324350:AOY20_RS08255
uniprot id: A0A0N9VDV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1324350:AOY20 RS08595
gene id: 1324350:AOY20_RS08595
uniprot id: A0A0N7GXT1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1324350:AOY20 RS01715
gene id: 1324350:AOY20_RS01715
uniprot id: A0A0N9VLW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1324350:AOY20 RS08085
gene id: 1324350:AOY20_RS08085
uniprot id: A0A0N9VT00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1324350:AOY20 RS04750
gene id: 1324350:AOY20_RS04750
uniprot id: A0A0N9VUU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1324350:AOY20 RS06545
gene id: 1324350:AOY20_RS06545
uniprot id: A0A0N9W0X8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1324350:AOY20 RS06345
gene id: 1324350:AOY20_RS06345
uniprot id: A0A0N9VD38
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1324350:AOY20 RS02560
gene id: 1324350:AOY20_RS02560
uniprot id: A0A0N9VWS0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1324350:AOY20 RS05555
gene id: 1324350:AOY20_RS05555
uniprot id: A0A0N7GXL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1324350:AOY20 RS01945
gene id: 1324350:AOY20_RS01945
uniprot id: A0A0N9W082
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1324350:AOY20 RS11400
gene id: 1324350:AOY20_RS11400
uniprot id: A0A0N9VF41
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS01975
gene id: 1324350:AOY20_RS01975
uniprot id: A0A0N9VYT4
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1324350:AOY20 RS01290
gene id: 1324350:AOY20_RS01290
uniprot id: A0A0N9VW61
names: Similarity
messages: Belongs to the GppA/Ppx family.

1324350:AOY20 RS13725
gene id: 1324350:AOY20_RS13725
uniprot id: A0A0N9W4C8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS08735
gene id: 1324350:AOY20_RS08735
uniprot id: A0A0N7GXT4
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1324350:AOY20 RS12770
gene id: 1324350:AOY20_RS12770
uniprot id: A0A0N7GY26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1324350:AOY20 RS13520
gene id: 1324350:AOY20_RS13520
uniprot id: A0A0N9W3Q8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1324350:AOY20 RS14280
gene id: 1324350:AOY20_RS14280
uniprot id: A0A0N9W9G4
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS03095
gene id: 1324350:AOY20_RS03095
uniprot id: A0A0N9VZA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1324350:AOY20 RS07425
gene id: 1324350:AOY20_RS07425
uniprot id: A0A0N9VDK8
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1324350:AOY20 RS12360
gene id: 1324350:AOY20_RS12360
uniprot id: A0A0N9WFN3
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

1324350:AOY20 RS06970
gene id: 1324350:AOY20_RS06970
uniprot id: A0A0N9VGX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1324350:AOY20 RS07610
gene id: 1324350:AOY20_RS07610
uniprot id: A0A0N9V8D4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1324350:AOY20 RS01865
gene id: 1324350:AOY20_RS01865
uniprot id: A0A0N9VYL3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS03040
gene id: 1324350:AOY20_RS03040
uniprot id: A0A0N9VZ72
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1324350:AOY20 RS05775
gene id: 1324350:AOY20_RS05775
uniprot id: A0A0N9W0J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1324350:AOY20 RS13670
gene id: 1324350:AOY20_RS13670
uniprot id: A0A0N7GY47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1324350:AOY20 RS03765
gene id: 1324350:AOY20_RS03765
uniprot id: A0A0N9VZJ4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1324350:AOY20 RS08545
gene id: 1324350:AOY20_RS08545
uniprot id: A0A0N9W3G9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS06295
gene id: 1324350:AOY20_RS06295
uniprot id: A0A0N9W0X9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1324350:AOY20 RS01805
gene id: 1324350:AOY20_RS01805
uniprot id: A0A0N9WAI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1324350:AOY20 RS01370
gene id: 1324350:AOY20_RS01370
uniprot id: A0A0N9WAA2
names: Similarity
messages: Belongs to the GST superfamily.

1324350:AOY20 RS05710
gene id: 1324350:AOY20_RS05710
uniprot id: A0A0N9W0H7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1324350:AOY20 RS08420
gene id: 1324350:AOY20_RS08420
uniprot id: A0A0N9V8Q0
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS04215
gene id: 1324350:AOY20_RS04215
uniprot id: A0A0N7GY67
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1324350:AOY20 RS07600
gene id: 1324350:AOY20_RS07600
uniprot id: A0A0N9VE46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS14050
gene id: 1324350:AOY20_RS14050
uniprot id: A0A0N9VYL6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS12165
gene id: 1324350:AOY20_RS12165
uniprot id: A0A0N9W361
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1324350:AOY20 RS13090
gene id: 1324350:AOY20_RS13090
uniprot id: A0A0N9VFR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1324350:AOY20 RS11170
gene id: 1324350:AOY20_RS11170
uniprot id: A0A0N9W2S7
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS03960
gene id: 1324350:AOY20_RS03960
uniprot id: A0A0N9VZM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1324350:AOY20 RS01680
gene id: 1324350:AOY20_RS01680
uniprot id: A0A0N7GXC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1324350:AOY20 RS07660
gene id: 1324350:AOY20_RS07660
uniprot id: A0A0N9WDS1
names: Similarity
messages: Belongs to the fabD family.

1324350:AOY20 RS02935
gene id: 1324350:AOY20_RS02935
uniprot id: A0A0N9VBX0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1324350:AOY20 RS02660
gene id: 1324350:AOY20_RS02660
uniprot id: A0A0N9W0I9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1324350:AOY20 RS09400
gene id: 1324350:AOY20_RS09400
uniprot id: A0A0N9WEH9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1324350:AOY20 RS12870
gene id: 1324350:AOY20_RS12870
uniprot id: A0A0N9VG46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

1324350:AOY20 RS12295
gene id: 1324350:AOY20_RS12295
uniprot id: A0A0N9VFW7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1324350:AOY20 RS09905
gene id: 1324350:AOY20_RS09905
uniprot id: A0A0N9VEH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1324350:AOY20 RS02745
gene id: 1324350:AOY20_RS02745
uniprot id: A0A0N9VWU0
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS13935
gene id: 1324350:AOY20_RS13935
uniprot id: A0A0N7GY53
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1324350:AOY20 RS04990
gene id: 1324350:AOY20_RS04990
uniprot id: A0A0N9VUY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1324350:AOY20 RS11715
gene id: 1324350:AOY20_RS11715
uniprot id: A0A0N9VS06
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1324350:AOY20 RS10720
gene id: 1324350:AOY20_RS10720
uniprot id: A0A0N9VET7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1324350:AOY20 RS00755
gene id: 1324350:AOY20_RS00755
uniprot id: A0A0N9W9X1
names: Similarity
messages: Belongs to the UPF0250 family.

1324350:AOY20 RS02130
gene id: 1324350:AOY20_RS02130
uniprot id: A0A0N9WAQ6
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1324350:AOY20 RS00930
gene id: 1324350:AOY20_RS00930
uniprot id: A0A0N9VY29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS09815
gene id: 1324350:AOY20_RS09815
uniprot id: A0A0N9W3Y6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1324350:AOY20 RS02295
gene id: 1324350:AOY20_RS02295
uniprot id: A0A0N9W0C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1324350:AOY20 RS04600
gene id: 1324350:AOY20_RS04600
uniprot id: A0A0N9VCQ3
names: Subunit
messages: Homodimer.

1324350:AOY20 RS01315
gene id: 1324350:AOY20_RS01315
uniprot id: A0A0N9WA87
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1324350:AOY20 RS13800
gene id: 1324350:AOY20_RS13800
uniprot id: A0A0N9W5H5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS10440
gene id: 1324350:AOY20_RS10440
uniprot id: A0A0N9VRD4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS14765
gene id: 1324350:AOY20_RS14765
uniprot id: A0A0N9WEW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1324350:AOY20 RS05665
gene id: 1324350:AOY20_RS05665
uniprot id: A0A0N9VD77
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1324350:AOY20 RS04540
gene id: 1324350:AOY20_RS04540
uniprot id: A0A0N7GXJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1324350:AOY20 RS14270
gene id: 1324350:AOY20_RS14270
uniprot id: A0A0N9VG88
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1324350:AOY20 RS07200
gene id: 1324350:AOY20_RS07200
uniprot id: A0A0N9W1A1
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

1324350:AOY20 RS04735
gene id: 1324350:AOY20_RS04735
uniprot id: A0A0N9VCS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1324350:AOY20 RS14230
gene id: 1324350:AOY20_RS14230
uniprot id: A0A0N9W5P0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1324350:AOY20 RS12240
gene id: 1324350:AOY20_RS12240
uniprot id: A0A0N9W4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1324350:AOY20 RS08580
gene id: 1324350:AOY20_RS08580
uniprot id: A0A0N9W242
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1324350:AOY20 RS04945
gene id: 1324350:AOY20_RS04945
uniprot id: A0A0N9VXS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1324350:AOY20 RS07115
gene id: 1324350:AOY20_RS07115
uniprot id: A0A0N9VPP1
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS02395
gene id: 1324350:AOY20_RS02395
uniprot id: A0A0N9WAW9
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS06785
gene id: 1324350:AOY20_RS06785
uniprot id: A0A0N9W2N9
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1324350:AOY20 RS06540
gene id: 1324350:AOY20_RS06540
uniprot id: A0A0N9W132
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1324350:AOY20 RS02070
gene id: 1324350:AOY20_RS02070
uniprot id: A0A0N9VBI8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1324350:AOY20 RS05330
gene id: 1324350:AOY20_RS05330
uniprot id: A0A0N9W0A6
names: Similarity
messages: Belongs to the RelA/SpoT family.

1324350:AOY20 RS05860
gene id: 1324350:AOY20_RS05860
uniprot id: A0A0N9VVE2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1324350:AOY20 RS00535
gene id: 1324350:AOY20_RS00535
uniprot id: A0A0N9VVT3
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS08120
gene id: 1324350:AOY20_RS08120
uniprot id: A0A0N9VGE1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS06155
gene id: 1324350:AOY20_RS06155
uniprot id: A0A0N9VP54
names: Similarity
messages: Belongs to the UPF0234 family.

1324350:AOY20 RS07565
gene id: 1324350:AOY20_RS07565
uniprot id: A0A0N7GXQ9
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS03125
gene id: 1324350:AOY20_RS03125
uniprot id: A0A0N7GXG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1324350:AOY20 RS12425
gene id: 1324350:AOY20_RS12425
uniprot id: A0A0N9WFP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1324350:AOY20 RS03400
gene id: 1324350:AOY20_RS03400
uniprot id: A0A0N9VC43
names: Similarity
messages: Belongs to the pirin family.

1324350:AOY20 RS11315
gene id: 1324350:AOY20_RS11315
uniprot id: A0A0N9VXM7
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

1324350:AOY20 RS10145
gene id: 1324350:AOY20_RS10145
uniprot id: A0A0N9W016
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

1324350:AOY20 RS00160
gene id: 1324350:AOY20_RS00160
uniprot id: A0A0N9VVL5
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS01170
gene id: 1324350:AOY20_RS01170
uniprot id: A0A0N9VY91
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1324350:AOY20 RS05575
gene id: 1324350:AOY20_RS05575
uniprot id: A0A0N9VNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS00590
gene id: 1324350:AOY20_RS00590
uniprot id: A0A0N7GXA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.

1324350:AOY20 RS09625
gene id: 1324350:AOY20_RS09625
uniprot id: A0A0N9VEE1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1324350:AOY20 RS02320
gene id: 1324350:AOY20_RS02320
uniprot id: A0A0N9VB35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1324350:AOY20 RS10775
gene id: 1324350:AOY20_RS10775
uniprot id: A0A0N9VRI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1324350:AOY20 RS12585
gene id: 1324350:AOY20_RS12585
uniprot id: A0A0N9W3M3
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1324350:AOY20 RS12920
gene id: 1324350:AOY20_RS12920
uniprot id: A0A0N9VFN5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1324350:AOY20 RS13560
gene id: 1324350:AOY20_RS13560
uniprot id: A0A0N9VSP1
names: Similarity
messages: Belongs to the aspartokinase family.

1324350:AOY20 RS10230
gene id: 1324350:AOY20_RS10230
uniprot id: A0A0N9WEV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS01135
gene id: 1324350:AOY20_RS01135
uniprot id: A0A0N9VST7
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1324350:AOY20 RS12885
gene id: 1324350:AOY20_RS12885
uniprot id: A0A0N9VY63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1324350:AOY20 RS04560
gene id: 1324350:AOY20_RS04560
uniprot id: A0A0N9VUQ4
names: Function
names: Similarity
messages: Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
messages: Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia.

1324350:AOY20 RS09515
gene id: 1324350:AOY20_RS09515
uniprot id: A0A0N9W2E8
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS00555
gene id: 1324350:AOY20_RS00555
uniprot id: A0A0N9VXX1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1324350:AOY20 RS11605
gene id: 1324350:AOY20_RS11605
uniprot id: A0A0N7GXZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1324350:AOY20 RS07045
gene id: 1324350:AOY20_RS07045
uniprot id: A0A0N9VVY8
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1324350:AOY20 RS02780
gene id: 1324350:AOY20_RS02780
uniprot id: A0A0N9W0L2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1324350:AOY20 RS03770
gene id: 1324350:AOY20_RS03770
uniprot id: A0A0N9WBG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS12265
gene id: 1324350:AOY20_RS12265
uniprot id: A0A0N9VFF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1324350:AOY20 RS05455
gene id: 1324350:AOY20_RS05455
uniprot id: A0A0N9W0G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1324350:AOY20 RS08455
gene id: 1324350:AOY20_RS08455
uniprot id: A0A0N7GXS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1324350:AOY20 RS05785
gene id: 1324350:AOY20_RS05785
uniprot id: A0A0N9VD95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS11270
gene id: 1324350:AOY20_RS11270
uniprot id: A0A0N9VDG9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1324350:AOY20 RS08175
gene id: 1324350:AOY20_RS08175
uniprot id: A0A0N9VWG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1324350:AOY20 RS12195
gene id: 1324350:AOY20_RS12195
uniprot id: A0A0N7GY13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1324350:AOY20 RS11670
gene id: 1324350:AOY20_RS11670
uniprot id: A0A0N9VF68
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1324350:AOY20 RS07250
gene id: 1324350:AOY20_RS07250
uniprot id: A0A0N9VDH8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1324350:AOY20 RS01485
gene id: 1324350:AOY20_RS01485
uniprot id: A0A0N9VAQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1324350:AOY20 RS00835
gene id: 1324350:AOY20_RS00835
uniprot id: A0A0N9V4Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1324350:AOY20 RS11910
gene id: 1324350:AOY20_RS11910
uniprot id: A0A0N9W0T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1324350:AOY20 RS09590
gene id: 1324350:AOY20_RS09590
uniprot id: A0A0N9VEU9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1324350:AOY20 RS00560
gene id: 1324350:AOY20_RS00560
uniprot id: A0A0N9W9S9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1324350:AOY20 RS07110
gene id: 1324350:AOY20_RS07110
uniprot id: A0A0N9VW01
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1324350:AOY20 RS04330
gene id: 1324350:AOY20_RS04330
uniprot id: A0A0N7GXI6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1324350:AOY20 RS08985
gene id: 1324350:AOY20_RS08985
uniprot id: A0A0N9VWR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1324350:AOY20 RS00675
gene id: 1324350:AOY20_RS00675
uniprot id: A0A0N9VAA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS00045
gene id: 1324350:AOY20_RS00045
uniprot id: A0A0N9VXK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1324350:AOY20 RS09735
gene id: 1324350:AOY20_RS09735
uniprot id: A0A0N9V973
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1324350:AOY20 RS03445
gene id: 1324350:AOY20_RS03445
uniprot id: A0A0N9VZE1
names: Similarity
messages: Belongs to the BolA/IbaG family.

1324350:AOY20 RS04480
gene id: 1324350:AOY20_RS04480
uniprot id: A0A0N9VCN6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1324350:AOY20 RS08230
gene id: 1324350:AOY20_RS08230
uniprot id: A0A0N9VWG7
names: Cofactor
messages: Can also use Mn(2+) ion.

1324350:AOY20 RS12565
gene id: 1324350:AOY20_RS12565
uniprot id: A0A0N9VSE4
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1324350:AOY20 RS08400
gene id: 1324350:AOY20_RS08400
uniprot id: A0A0N9WDZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS10160
gene id: 1324350:AOY20_RS10160
uniprot id: A0A0N9W2E3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1324350:AOY20 RS01765
gene id: 1324350:AOY20_RS01765
uniprot id: A0A0N9V573
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS03645
gene id: 1324350:AOY20_RS03645
uniprot id: A0A0N9VZH2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1324350:AOY20 RS11295
gene id: 1324350:AOY20_RS11295
uniprot id: A0A0N9WF77
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1324350:AOY20 RS13420
gene id: 1324350:AOY20_RS13420
uniprot id: A0A0N9VGB4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS14200
gene id: 1324350:AOY20_RS14200
uniprot id: A0A0N9VG80
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS14130
gene id: 1324350:AOY20_RS14130
uniprot id: A0A0N9VSV1
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1324350:AOY20 RS03625
gene id: 1324350:AOY20_RS03625
uniprot id: A0A0N9VMS3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1324350:AOY20 RS04125
gene id: 1324350:AOY20_RS04125
uniprot id: A0A0N9VBZ3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1324350:AOY20 RS04575
gene id: 1324350:AOY20_RS04575
uniprot id: A0A0N9VC97
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS11105
gene id: 1324350:AOY20_RS11105
uniprot id: A0A0N9W327
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1324350:AOY20 RS09520
gene id: 1324350:AOY20_RS09520
uniprot id: A0A0N9W257
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1324350:AOY20 RS00970
gene id: 1324350:AOY20_RS00970
uniprot id: A0A0N9VW12
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS03840
gene id: 1324350:AOY20_RS03840
uniprot id: A0A0N9W143
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1324350:AOY20 RS05825
gene id: 1324350:AOY20_RS05825
uniprot id: A0A0N9W0N9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS02455
gene id: 1324350:AOY20_RS02455
uniprot id: A0A0N9VYX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1324350:AOY20 RS05840
gene id: 1324350:AOY20_RS05840
uniprot id: A0A0N7GXM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1324350:AOY20 RS11275
gene id: 1324350:AOY20_RS11275
uniprot id: A0A0N9VF22
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1324350:AOY20 RS11335
gene id: 1324350:AOY20_RS11335
uniprot id: A0A0N9W200
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS06445
gene id: 1324350:AOY20_RS06445
uniprot id: A0A0N9W2H8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1324350:AOY20 RS12085
gene id: 1324350:AOY20_RS12085
uniprot id: A0A0N9W0V9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS11385
gene id: 1324350:AOY20_RS11385
uniprot id: A0A0N9VXN0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1324350:AOY20 RS12320
gene id: 1324350:AOY20_RS12320
uniprot id: A0A0N7GY16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS04900
gene id: 1324350:AOY20_RS04900
uniprot id: A0A0N9W033
names: Similarity
messages: Belongs to the SsuE family.

1324350:AOY20 RS03285
gene id: 1324350:AOY20_RS03285
uniprot id: A0A0N9V5X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1324350:AOY20 RS01950
gene id: 1324350:AOY20_RS01950
uniprot id: A0A0N9V5A3
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1324350:AOY20 RS00445
gene id: 1324350:AOY20_RS00445
uniprot id: A0A0N9VAU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1324350:AOY20 RS11160
gene id: 1324350:AOY20_RS11160
uniprot id: A0A0N9VF03
names: Similarity
messages: Belongs to the peptidase M16 family.

1324350:AOY20 RS01905
gene id: 1324350:AOY20_RS01905
uniprot id: A0A0N9VWF9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1324350:AOY20 RS13350
gene id: 1324350:AOY20_RS13350
uniprot id: A0A0N9WG32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1324350:AOY20 RS03605
gene id: 1324350:AOY20_RS03605
uniprot id: A0A0N9V630
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1324350:AOY20 RS03660
gene id: 1324350:AOY20_RS03660
uniprot id: A0A0N9VC83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1324350:AOY20 RS03710
gene id: 1324350:AOY20_RS03710
uniprot id: A0A0N9WBF0
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1324350:AOY20 RS11975
gene id: 1324350:AOY20_RS11975
uniprot id: A0A0N9VFA4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS11665
gene id: 1324350:AOY20_RS11665
uniprot id: A0A0N9VBE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1324350:AOY20 RS00420
gene id: 1324350:AOY20_RS00420
uniprot id: A0A0N9VA53
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS01000
gene id: 1324350:AOY20_RS01000
uniprot id: A0A0N9VB18
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1324350:AOY20 RS03015
gene id: 1324350:AOY20_RS03015
uniprot id: A0A0N9VTU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1324350:AOY20 RS08350
gene id: 1324350:AOY20_RS08350
uniprot id: A0A0N9W3E2
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1324350:AOY20 RS05875
gene id: 1324350:AOY20_RS05875
uniprot id: A0A0N9VY93
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1324350:AOY20 RS04405
gene id: 1324350:AOY20_RS04405
uniprot id: A0A0N9VZU3
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS01995
gene id: 1324350:AOY20_RS01995
uniprot id: A0A0N9VBI1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1324350:AOY20 RS12675
gene id: 1324350:AOY20_RS12675
uniprot id: A0A0N9WGR8
names: Similarity
messages: Belongs to the IMPACT family.

1324350:AOY20 RS02200
gene id: 1324350:AOY20_RS02200
uniprot id: A0A0N9VB10
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1324350:AOY20 RS09405
gene id: 1324350:AOY20_RS09405
uniprot id: A0A0N9VET1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1324350:AOY20 RS13080
gene id: 1324350:AOY20_RS13080
uniprot id: A0A0N9VSJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS08550
gene id: 1324350:AOY20_RS08550
uniprot id: A0A0N9V8R8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1324350:AOY20 RS00810
gene id: 1324350:AOY20_RS00810
uniprot id: A0A0N9VY05
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1324350:AOY20 RS07520
gene id: 1324350:AOY20_RS07520
uniprot id: A0A0N9W1F5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1324350:AOY20 RS05220
gene id: 1324350:AOY20_RS05220
uniprot id: A0A0N9WCA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1324350:AOY20 RS03090
gene id: 1324350:AOY20_RS03090
uniprot id: A0A0N9VBF5
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1324350:AOY20 RS09240
gene id: 1324350:AOY20_RS09240
uniprot id: A0A0N9VE95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS03390
gene id: 1324350:AOY20_RS03390
uniprot id: A0A0N9VZC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1324350:AOY20 RS07060
gene id: 1324350:AOY20_RS07060
uniprot id: A0A0N9VDF4
names: Similarity
messages: Belongs to the GSP E family.

1324350:AOY20 RS06925
gene id: 1324350:AOY20_RS06925
uniprot id: A0A0N9VPK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1324350:AOY20 RS12105
gene id: 1324350:AOY20_RS12105
uniprot id: A0A0N9WFJ7
names: Similarity
messages: Belongs to the MipA/OmpV family.

1324350:AOY20 RS13115
gene id: 1324350:AOY20_RS13115
uniprot id: A0A0N9VG73
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1324350:AOY20 RS05500
gene id: 1324350:AOY20_RS05500
uniprot id: A0A0N9VY33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS03420
gene id: 1324350:AOY20_RS03420
uniprot id: A0A0N9VMP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1324350:AOY20 RS02330
gene id: 1324350:AOY20_RS02330
uniprot id: A0A0N9VYZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1324350:AOY20 RS03940
gene id: 1324350:AOY20_RS03940
uniprot id: A0A0N9VMY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1324350:AOY20 RS13380
gene id: 1324350:AOY20_RS13380
uniprot id: A0A0N9VYD1
names: Similarity
messages: Belongs to the Gfa family.

1324350:AOY20 RS11840
gene id: 1324350:AOY20_RS11840
uniprot id: A0A0N9VS27
names: Subcellular Location Annotation
messages: Cytoplasm

1324350:AOY20 RS12495
gene id: 1324350:AOY20_RS12495
uniprot id: A0A0N9VAB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1324350:AOY20 RS00645
gene id: 1324350:AOY20_RS00645
uniprot id: A0A0N7GXA4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS14005
gene id: 1324350:AOY20_RS14005
uniprot id: A0A0N9VG54
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS13640
gene id: 1324350:AOY20_RS13640
uniprot id: A0A0N9VFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1324350:AOY20 RS13010
gene id: 1324350:AOY20_RS13010
uniprot id: A0A0N9VAK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1324350:AOY20 RS00580
gene id: 1324350:AOY20_RS00580
uniprot id: A0A0N9V4K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS09915
gene id: 1324350:AOY20_RS09915
uniprot id: A0A0N9W2K5
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS10570
gene id: 1324350:AOY20_RS10570
uniprot id: A0A0N9VES0
names: Similarity
messages: Belongs to the UPF0319 family.

1324350:AOY20 RS08565
gene id: 1324350:AOY20_RS08565
uniprot id: A0A0N9VQD2
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS05225
gene id: 1324350:AOY20_RS05225
uniprot id: A0A0N9VD00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS04845
gene id: 1324350:AOY20_RS04845
uniprot id: A0A0N7GXJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1324350:AOY20 RS03795
gene id: 1324350:AOY20_RS03795
uniprot id: A0A0N9VUC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1324350:AOY20 RS13955
gene id: 1324350:AOY20_RS13955
uniprot id: A0A0N9W478
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS02120
gene id: 1324350:AOY20_RS02120
uniprot id: A0A0N9VYR7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1324350:AOY20 RS06615
gene id: 1324350:AOY20_RS06615
uniprot id: A0A0N9VDM3
names: Similarity
messages: Belongs to the TrpF family.

1324350:AOY20 RS06070
gene id: 1324350:AOY20_RS06070
uniprot id: A0A0N7GXM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1324350:AOY20 RS00100
gene id: 1324350:AOY20_RS00100
uniprot id: A0A0N9VVK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1324350:AOY20 RS12055
gene id: 1324350:AOY20_RS12055
uniprot id: A0A0N9VFS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1324350:AOY20 RS09230
gene id: 1324350:AOY20_RS09230
uniprot id: A0A0N7GXU6
names: Similarity
messages: Belongs to the ArsC family.

1324350:AOY20 RS00405
gene id: 1324350:AOY20_RS00405
uniprot id: A0A0N9VL94
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1324350:AOY20 RS11425
gene id: 1324350:AOY20_RS11425
uniprot id: A0A0N9VFJ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1324350:AOY20 RS04800
gene id: 1324350:AOY20_RS04800
uniprot id: A0A0N9W1L6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1324350:AOY20 RS09570
gene id: 1324350:AOY20_RS09570
uniprot id: A0A0N9VED4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS07885
gene id: 1324350:AOY20_RS07885
uniprot id: A0A0N9WDU2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS00385
gene id: 1324350:AOY20_RS00385
uniprot id: A0A0N9VAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1324350:AOY20 RS12955
gene id: 1324350:AOY20_RS12955
uniprot id: A0A0N7GY30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1324350:AOY20 RS02565
gene id: 1324350:AOY20_RS02565
uniprot id: A0A0N7GY65
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1324350:AOY20 RS12990
gene id: 1324350:AOY20_RS12990
uniprot id: A0A0N9WFX5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1324350:AOY20 RS01565
gene id: 1324350:AOY20_RS01565
uniprot id: A0A0N9WAE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1324350:AOY20 RS13390
gene id: 1324350:AOY20_RS13390
uniprot id: A0A0N9W1C0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1324350:AOY20 RS08905
gene id: 1324350:AOY20_RS08905
uniprot id: A0A0N9VEL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS08365
gene id: 1324350:AOY20_RS08365
uniprot id: A0A0N9VQB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1324350:AOY20 RS00545
gene id: 1324350:AOY20_RS00545
uniprot id: A0A0N7GXA2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1324350:AOY20 RS06400
gene id: 1324350:AOY20_RS06400
uniprot id: A0A0N9VYH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1324350:AOY20 RS07260
gene id: 1324350:AOY20_RS07260
uniprot id: A0A0N9W1F7
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS03295
gene id: 1324350:AOY20_RS03295
uniprot id: A0A0N7GXG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1324350:AOY20 RS10425
gene id: 1324350:AOY20_RS10425
uniprot id: A0A0N9V9G4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1324350:AOY20 RS04580
gene id: 1324350:AOY20_RS04580
uniprot id: A0A0N7GXJ2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS00215
gene id: 1324350:AOY20_RS00215
uniprot id: A0A0N9VZA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1324350:AOY20 RS02290
gene id: 1324350:AOY20_RS02290
uniprot id: A0A0N9VBL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1324350:AOY20 RS13310
gene id: 1324350:AOY20_RS13310
uniprot id: A0A0N9VAQ3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1324350:AOY20 RS07055
gene id: 1324350:AOY20_RS07055
uniprot id: A0A0N9VYS7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS02475
gene id: 1324350:AOY20_RS02475
uniprot id: A0A0N9W0F7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1324350:AOY20 RS05235
gene id: 1324350:AOY20_RS05235
uniprot id: A0A0N7GXK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1324350:AOY20 RS01980
gene id: 1324350:AOY20_RS01980
uniprot id: A0A0N7GXD5
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS11355
gene id: 1324350:AOY20_RS11355
uniprot id: A0A0N9W2V0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS08160
gene id: 1324350:AOY20_RS08160
uniprot id: A0A0N9VEB7
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1324350:AOY20 RS05835
gene id: 1324350:AOY20_RS05835
uniprot id: A0A0N9WCL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

1324350:AOY20 RS02785
gene id: 1324350:AOY20_RS02785
uniprot id: A0A0N9V5P3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1324350:AOY20 RS06280
gene id: 1324350:AOY20_RS06280
uniprot id: A0A0N9VP79
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1324350:AOY20 RS02280
gene id: 1324350:AOY20_RS02280
uniprot id: A0A0N9WAT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1324350:AOY20 RS12995
gene id: 1324350:AOY20_RS12995
uniprot id: A0A0N7GY31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1324350:AOY20 RS03425
gene id: 1324350:AOY20_RS03425
uniprot id: A0A0N7GXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS04055
gene id: 1324350:AOY20_RS04055
uniprot id: A0A0N9VN11
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1324350:AOY20 RS14025
gene id: 1324350:AOY20_RS14025
uniprot id: A0A0N9W3Y1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1324350:AOY20 RS00830
gene id: 1324350:AOY20_RS00830
uniprot id: A0A0N9VZK6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1324350:AOY20 RS12500
gene id: 1324350:AOY20_RS12500
uniprot id: A0A0N7GY20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1324350:AOY20 RS12115
gene id: 1324350:AOY20_RS12115
uniprot id: A0A0N9VFT9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1324350:AOY20 RS03675
gene id: 1324350:AOY20_RS03675
uniprot id: A0A0N9VU87
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1324350:AOY20 RS04680
gene id: 1324350:AOY20_RS04680
uniprot id: A0A0N9VUT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1324350:AOY20 RS09880
gene id: 1324350:AOY20_RS09880
uniprot id: A0A0N9V987
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1324350:AOY20 RS00440
gene id: 1324350:AOY20_RS00440
uniprot id: A0A0N9W9P7
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1324350:AOY20 RS01445
gene id: 1324350:AOY20_RS01445
uniprot id: A0A0N9VB86
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1324350:AOY20 RS05495
gene id: 1324350:AOY20_RS05495
uniprot id: A0A0N9VNU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1324350:AOY20 RS01125
gene id: 1324350:AOY20_RS01125
uniprot id: A0A0N9VZS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1324350:AOY20 RS06945
gene id: 1324350:AOY20_RS06945
uniprot id: A0A0N9W1A3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS02115
gene id: 1324350:AOY20_RS02115
uniprot id: A0A0N9VYV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1324350:AOY20 RS11630
gene id: 1324350:AOY20_RS11630
uniprot id: A0A0N9VFM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1324350:AOY20 RS10890
gene id: 1324350:AOY20_RS10890
uniprot id: A0A0N9VXH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1324350:AOY20 RS08995
gene id: 1324350:AOY20_RS08995
uniprot id: A0A0N9VZM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS10115
gene id: 1324350:AOY20_RS10115
uniprot id: A0A0N9VF13
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1324350:AOY20 RS10670
gene id: 1324350:AOY20_RS10670
uniprot id: A0A0N7GXX8
names: Subcellular Location Annotation
messages: Cytoplasm

1324350:AOY20 RS08950
gene id: 1324350:AOY20_RS08950
uniprot id: A0A0N9W288
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1324350:AOY20 RS02855
gene id: 1324350:AOY20_RS02855
uniprot id: A0A0N9WB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1324350:AOY20 RS12940
gene id: 1324350:AOY20_RS12940
uniprot id: A0A0N9VG53
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS10755
gene id: 1324350:AOY20_RS10755
uniprot id: A0A0N9VGZ5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1324350:AOY20 RS12185
gene id: 1324350:AOY20_RS12185
uniprot id: A0A0N9VA79
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS12120
gene id: 1324350:AOY20_RS12120
uniprot id: A0A0N9W4U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1324350:AOY20 RS03935
gene id: 1324350:AOY20_RS03935
uniprot id: A0A0N9VUE4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1324350:AOY20 RS03805
gene id: 1324350:AOY20_RS03805
uniprot id: A0A0N9VXA6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS11130
gene id: 1324350:AOY20_RS11130
uniprot id: A0A0N9W4G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS09930
gene id: 1324350:AOY20_RS09930
uniprot id: A0A0N7GXW1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1324350:AOY20 RS13210
gene id: 1324350:AOY20_RS13210
uniprot id: A0A0N9W186
names: Function
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
messages: Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.

1324350:AOY20 RS12510
gene id: 1324350:AOY20_RS12510
uniprot id: A0A0N9VSD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1324350:AOY20 RS04025
gene id: 1324350:AOY20_RS04025
uniprot id: A0A0N9WBJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1324350:AOY20 RS02610
gene id: 1324350:AOY20_RS02610
uniprot id: A0A0N9W447
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS13355
gene id: 1324350:AOY20_RS13355
uniprot id: A0A0N9VGA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1324350:AOY20 RS14235
gene id: 1324350:AOY20_RS14235
uniprot id: A0A0N9VB37
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1324350:AOY20 RS01380
gene id: 1324350:AOY20_RS01380
uniprot id: A0A0N7GXC1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS03630
gene id: 1324350:AOY20_RS03630
uniprot id: A0A0N9VX73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1324350:AOY20 RS10620
gene id: 1324350:AOY20_RS10620
uniprot id: A0A0N9W493
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1324350:AOY20 RS07605
gene id: 1324350:AOY20_RS07605
uniprot id: A0A0N9W341
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1324350:AOY20 RS02600
gene id: 1324350:AOY20_RS02600
uniprot id: A0A0N9W0H8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1324350:AOY20 RS06415
gene id: 1324350:AOY20_RS06415
uniprot id: A0A0N9W0V4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS01275
gene id: 1324350:AOY20_RS01275
uniprot id: A0A0N9V4W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1324350:AOY20 RS10225
gene id: 1324350:AOY20_RS10225
uniprot id: A0A0N7GXW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1324350:AOY20 RS05790
gene id: 1324350:AOY20_RS05790
uniprot id: A0A0N9W234
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1324350:AOY20 RS11320
gene id: 1324350:AOY20_RS11320
uniprot id: A0A0N7GXZ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS02480
gene id: 1324350:AOY20_RS02480
uniprot id: A0A0N9V5J2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1324350:AOY20 RS07480
gene id: 1324350:AOY20_RS07480
uniprot id: A0A0N9VPW6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1324350:AOY20 RS07665
gene id: 1324350:AOY20_RS07665
uniprot id: A0A0N7GXR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1324350:AOY20 RS02535
gene id: 1324350:AOY20_RS02535
uniprot id: A0A0N7GXE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1324350:AOY20 RS00725
gene id: 1324350:AOY20_RS00725
uniprot id: A0A0N7GXA6
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1324350:AOY20 RS00040
gene id: 1324350:AOY20_RS00040
uniprot id: A0A0N9VG88
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1324350:AOY20 RS12945
gene id: 1324350:AOY20_RS12945
uniprot id: A0A0N9W564
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1324350:AOY20 RS06685
gene id: 1324350:AOY20_RS06685
uniprot id: A0A0N9VGD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1324350:AOY20 RS08305
gene id: 1324350:AOY20_RS08305
uniprot id: A0A0N9VQA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS13500
gene id: 1324350:AOY20_RS13500
uniprot id: A0A0N9VSN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS06765
gene id: 1324350:AOY20_RS06765
uniprot id: A0A0N9W112
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1324350:AOY20 RS08525
gene id: 1324350:AOY20_RS08525
uniprot id: A0A0N9W1S0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1324350:AOY20 RS10560
gene id: 1324350:AOY20_RS10560
uniprot id: A0A0N7GXX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1324350:AOY20 RS02380
gene id: 1324350:AOY20_RS02380
uniprot id: A0A0N9VB44
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS01695
gene id: 1324350:AOY20_RS01695
uniprot id: A0A0N9VBC7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1324350:AOY20 RS07800
gene id: 1324350:AOY20_RS07800
uniprot id: A0A0N9VWD1
names: Similarity
messages: Belongs to the YkuD family.

1324350:AOY20 RS11945
gene id: 1324350:AOY20_RS11945
uniprot id: A0A0N9W4S8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1324350:AOY20 RS13565
gene id: 1324350:AOY20_RS13565
uniprot id: A0A0N9W1E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1324350:AOY20 RS10780
gene id: 1324350:AOY20_RS10780
uniprot id: A0A0N9W0C4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1324350:AOY20 RS06110
gene id: 1324350:AOY20_RS06110
uniprot id: A0A0N9W0U5
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS04670
gene id: 1324350:AOY20_RS04670
uniprot id: A0A0N9W1I3
names: Similarity
messages: Belongs to the ArsC family.

1324350:AOY20 RS07240
gene id: 1324350:AOY20_RS07240
uniprot id: A0A0N9VPR3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1324350:AOY20 RS00395
gene id: 1324350:AOY20_RS00395
uniprot id: A0A0N9V4H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1324350:AOY20 RS10700
gene id: 1324350:AOY20_RS10700
uniprot id: A0A0N9VXF0
names: Subcellular Location Annotation
messages: Membrane

1324350:AOY20 RS02630
gene id: 1324350:AOY20_RS02630
uniprot id: A0A0N7GXE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1324350:AOY20 RS08010
gene id: 1324350:AOY20_RS08010
uniprot id: A0A0N9WDV8
names: Similarity
messages: Belongs to the TrpC family.

1324350:AOY20 RS06030
gene id: 1324350:AOY20_RS06030
uniprot id: A0A0N9W0N7
names: Similarity
messages: Belongs to the PhoH family.

1324350:AOY20 RS12715
gene id: 1324350:AOY20_RS12715
uniprot id: A0A0N9VFL4
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1324350:AOY20 RS08135
gene id: 1324350:AOY20_RS08135
uniprot id: A0A0N9W1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS03050
gene id: 1324350:AOY20_RS03050
uniprot id: A0A0N9WB68
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1324350:AOY20 RS04320
gene id: 1324350:AOY20_RS04320
uniprot id: A0A0N9VUK5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1324350:AOY20 RS00370
gene id: 1324350:AOY20_RS00370
uniprot id: A0A0N9VXT0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1324350:AOY20 RS13100
gene id: 1324350:AOY20_RS13100
uniprot id: A0A0N9W3J4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1324350:AOY20 RS00310
gene id: 1324350:AOY20_RS00310
uniprot id: A0A0N9VXW7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS08440
gene id: 1324350:AOY20_RS08440
uniprot id: A0A0N9VDY1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1324350:AOY20 RS00035
gene id: 1324350:AOY20_RS00035
uniprot id: A0A0N9V9Z3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS09360
gene id: 1324350:AOY20_RS09360
uniprot id: A0A0N9V921
names: Subcellular Location Annotation
messages: Cytoplasm

1324350:AOY20 RS02105
gene id: 1324350:AOY20_RS02105
uniprot id: A0A0N9VWJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1324350:AOY20 RS08790
gene id: 1324350:AOY20_RS08790
uniprot id: A0A0N9VEJ9
names: Similarity
messages: Belongs to the peptidase S11 family.

1324350:AOY20 RS06205
gene id: 1324350:AOY20_RS06205
uniprot id: A0A0N9VVK3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS03060
gene id: 1324350:AOY20_RS03060
uniprot id: A0A0N9W0Q7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1324350:AOY20 RS08825
gene id: 1324350:AOY20_RS08825
uniprot id: A0A0N9VE36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1324350:AOY20 RS00815
gene id: 1324350:AOY20_RS00815
uniprot id: A0A0N7GXA8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS08505
gene id: 1324350:AOY20_RS08505
uniprot id: A0A0N9VDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1324350:AOY20 RS02905
gene id: 1324350:AOY20_RS02905
uniprot id: A0A0N9VBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1324350:AOY20 RS00115
gene id: 1324350:AOY20_RS00115
uniprot id: A0A0N9VXT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1324350:AOY20 RS02245
gene id: 1324350:AOY20_RS02245
uniprot id: A0A0N7GXE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1324350:AOY20 RS03140
gene id: 1324350:AOY20_RS03140
uniprot id: A0A0N9VX07
names: Similarity
messages: Belongs to the LOG family.

1324350:AOY20 RS00575
gene id: 1324350:AOY20_RS00575
uniprot id: A0A0N9VZG4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1324350:AOY20 RS07950
gene id: 1324350:AOY20_RS07950
uniprot id: A0A0N9W376
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1324350:AOY20 RS11075
gene id: 1324350:AOY20_RS11075
uniprot id: A0A0N9V9P3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1324350:AOY20 RS12390
gene id: 1324350:AOY20_RS12390
uniprot id: A0A0N9VSB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1324350:AOY20 RS10090
gene id: 1324350:AOY20_RS10090
uniprot id: A0A0N9VEK1
names: Subcellular Location Annotation
messages: Cell surface

1324350:AOY20 RS13480
gene id: 1324350:AOY20_RS13480
uniprot id: A0A0N9W5D7
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1324350:AOY20 RS02285
gene id: 1324350:AOY20_RS02285
uniprot id: A0A0N7GXE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1324350:AOY20 RS11305
gene id: 1324350:AOY20_RS11305
uniprot id: A0A0N9W4K1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1324350:AOY20 RS10455
gene id: 1324350:AOY20_RS10455
uniprot id: A0A0N9W2T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS14060
gene id: 1324350:AOY20_RS14060
uniprot id: A0A0N7GY56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1324350:AOY20 RS08330
gene id: 1324350:AOY20_RS08330
uniprot id: A0A0N9W1Q0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1324350:AOY20 RS04115
gene id: 1324350:AOY20_RS04115
uniprot id: A0A0N9VXH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1324350:AOY20 RS09500
gene id: 1324350:AOY20_RS09500
uniprot id: A0A0N9VZU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS04855
gene id: 1324350:AOY20_RS04855
uniprot id: A0A0N9VCU6
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS03340
gene id: 1324350:AOY20_RS03340
uniprot id: A0A0N9W0V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS03310
gene id: 1324350:AOY20_RS03310
uniprot id: A0A0N9VBJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1324350:AOY20 RS04020
gene id: 1324350:AOY20_RS04020
uniprot id: A0A0N9VZN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

1324350:AOY20 RS05510
gene id: 1324350:AOY20_RS05510
uniprot id: A0A0N9W0I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1324350:AOY20 RS07360
gene id: 1324350:AOY20_RS07360
uniprot id: A0A0N9VYY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1324350:AOY20 RS00865
gene id: 1324350:AOY20_RS00865
uniprot id: A0A0N9VY57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1324350:AOY20 RS02225
gene id: 1324350:AOY20_RS02225
uniprot id: A0A0N9VBL0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1324350:AOY20 RS10965
gene id: 1324350:AOY20_RS10965
uniprot id: A0A0N9W0F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

1324350:AOY20 RS12335
gene id: 1324350:AOY20_RS12335
uniprot id: A0A0N9VFG1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1324350:AOY20 RS13665
gene id: 1324350:AOY20_RS13665
uniprot id: A0A0N9W5G1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1324350:AOY20 RS11520
gene id: 1324350:AOY20_RS11520
uniprot id: A0A0N9VRY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS05800
gene id: 1324350:AOY20_RS05800
uniprot id: A0A0N7GXM0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS13990
gene id: 1324350:AOY20_RS13990
uniprot id: A0A0N9VYK7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1324350:AOY20 RS13515
gene id: 1324350:AOY20_RS13515
uniprot id: A0A0N9W421
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1324350:AOY20 RS04765
gene id: 1324350:AOY20_RS04765
uniprot id: A0A0N9VXQ8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1324350:AOY20 RS05265
gene id: 1324350:AOY20_RS05265
uniprot id: A0A0N9W0D0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1324350:AOY20 RS01075
gene id: 1324350:AOY20_RS01075
uniprot id: A0A0N9VSS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS04620
gene id: 1324350:AOY20_RS04620
uniprot id: A0A0N7GXJ3
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

1324350:AOY20 RS00335
gene id: 1324350:AOY20_RS00335
uniprot id: A0A0N7GX97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1324350:AOY20 RS00925
gene id: 1324350:AOY20_RS00925
uniprot id: A0A0N9VY66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1324350:AOY20 RS06140
gene id: 1324350:AOY20_RS06140
uniprot id: A0A0N7GXM7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1324350:AOY20 RS11765
gene id: 1324350:AOY20_RS11765
uniprot id: A0A0N9V9Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1324350:AOY20 RS06075
gene id: 1324350:AOY20_RS06075
uniprot id: A0A0N9VYC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1324350:AOY20 RS02665
gene id: 1324350:AOY20_RS02665
uniprot id: A0A0N9V5M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

1324350:AOY20 RS06180
gene id: 1324350:AOY20_RS06180
uniprot id: A0A0N7GXM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1324350:AOY20 RS14255
gene id: 1324350:AOY20_RS14255
uniprot id: A0A0N9VYP0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

1324350:AOY20 RS06605
gene id: 1324350:AOY20_RS06605
uniprot id: A0A0N7GXN8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1324350:AOY20 RS04205
gene id: 1324350:AOY20_RS04205
uniprot id: A0A0N9VN33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1324350:AOY20 RS07785
gene id: 1324350:AOY20_RS07785
uniprot id: A0A0N7GXR4
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1324350:AOY20 RS11750
gene id: 1324350:AOY20_RS11750
uniprot id: A0A0N9VFN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1324350:AOY20 RS05160
gene id: 1324350:AOY20_RS05160
uniprot id: A0A0N9WC85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1324350:AOY20 RS03410
gene id: 1324350:AOY20_RS03410
uniprot id: A0A0N9V5Z1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1324350:AOY20 RS04470
gene id: 1324350:AOY20_RS04470
uniprot id: A0A0N9VZV6
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1324350:AOY20 RS09720
gene id: 1324350:AOY20_RS09720
uniprot id: A0A0N9VEX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1324350:AOY20 RS13840
gene id: 1324350:AOY20_RS13840
uniprot id: A0A0N9W3V2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1324350:AOY20 RS09605
gene id: 1324350:AOY20_RS09605
uniprot id: A0A0N9V951
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1324350:AOY20 RS07570
gene id: 1324350:AOY20_RS07570
uniprot id: A0A0N9VDN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1324350:AOY20 RS13165
gene id: 1324350:AOY20_RS13165
uniprot id: A0A0N9W3K6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1324350:AOY20 RS01560
gene id: 1324350:AOY20_RS01560
uniprot id: A0A0N9VYG7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1324350:AOY20 RS02215
gene id: 1324350:AOY20_RS02215
uniprot id: A0A0N9WAS7
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1324350:AOY20 RS00665
gene id: 1324350:AOY20_RS00665
uniprot id: A0A0N9VLC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1324350:AOY20 RS11770
gene id: 1324350:AOY20_RS11770
uniprot id: A0A0N9VXT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1324350:AOY20 RS12325
gene id: 1324350:AOY20_RS12325
uniprot id: A0A0N9W0Y8
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1324350:AOY20 RS11705
gene id: 1324350:AOY20_RS11705
uniprot id: A0A0N9V9Y4
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1324350:AOY20 RS07185
gene id: 1324350:AOY20_RS07185
uniprot id: A0A0N9VYU6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1324350:AOY20 RS11935
gene id: 1324350:AOY20_RS11935
uniprot id: A0A0N7GY76
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS00585
gene id: 1324350:AOY20_RS00585
uniprot id: A0A0N9VSH4
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1324350:AOY20 RS06950
gene id: 1324350:AOY20_RS06950
uniprot id: A0A0N7GXP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1324350:AOY20 RS02300
gene id: 1324350:AOY20_RS02300
uniprot id: A0A0N9V5F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1324350:AOY20 RS02685
gene id: 1324350:AOY20_RS02685
uniprot id: A0A0N9VWT3
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

1324350:AOY20 RS04240
gene id: 1324350:AOY20_RS04240
uniprot id: A0A0N9VCI4
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

1324350:AOY20 RS09545
gene id: 1324350:AOY20_RS09545
uniprot id: A0A0N9V941
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1324350:AOY20 RS02765
gene id: 1324350:AOY20_RS02765
uniprot id: A0A0N9VZ33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1324350:AOY20 RS01825
gene id: 1324350:AOY20_RS01825
uniprot id: A0A0N9W058
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1324350:AOY20 RS13895
gene id: 1324350:AOY20_RS13895
uniprot id: A0A0N9W475
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1324350:AOY20 RS00450
gene id: 1324350:AOY20_RS00450
uniprot id: A0A0N9VZE2
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1324350:AOY20 RS01470
gene id: 1324350:AOY20_RS01470
uniprot id: A0A0N7GXC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1324350:AOY20 RS03180
gene id: 1324350:AOY20_RS03180
uniprot id: A0A0N9VC11
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1324350:AOY20 RS01255
gene id: 1324350:AOY20_RS01255
uniprot id: A0A0N7GXB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1324350:AOY20 RS09835
gene id: 1324350:AOY20_RS09835
uniprot id: A0A0N9VZX9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1324350:AOY20 RS13630
gene id: 1324350:AOY20_RS13630
uniprot id: A0A0N7GY46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1324350:AOY20 RS10915
gene id: 1324350:AOY20_RS10915
uniprot id: A0A0N9VEW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1324350:AOY20 RS04400
gene id: 1324350:AOY20_RS04400
uniprot id: A0A0N9VZW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1324350:AOY20 RS05475
gene id: 1324350:AOY20_RS05475
uniprot id: A0A0N9W1Y2
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1324350:AOY20 RS12190
gene id: 1324350:AOY20_RS12190
uniprot id: A0A0N9VXY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1324350:AOY20 RS11310
gene id: 1324350:AOY20_RS11310
uniprot id: A0A0N9V9S6
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1324350:AOY20 RS09480
gene id: 1324350:AOY20_RS09480
uniprot id: A0A0N9W3U3
names: Subcellular Location Annotation
messages: Membrane