1322246:BN4 RS04600
gene id: 1322246:BN4_RS04600
uniprot id: M1WR67
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS16555
gene id: 1322246:BN4_RS16555
uniprot id: M1WYR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1322246:BN4 RS16715
gene id: 1322246:BN4_RS16715
uniprot id: M1WNS6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1322246:BN4 RS01895
gene id: 1322246:BN4_RS01895
uniprot id: M1WUM6
names: Similarity
messages: Belongs to the YggT family.

1322246:BN4 RS12965
gene id: 1322246:BN4_RS12965
uniprot id: M1WMN0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1322246:BN4 RS09625
gene id: 1322246:BN4_RS09625
uniprot id: M1WQS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1322246:BN4 RS13950
gene id: 1322246:BN4_RS13950
uniprot id: M1WS72
names: Similarity
messages: Belongs to the peptidase S49 family.

1322246:BN4 RS15650
gene id: 1322246:BN4_RS15650
uniprot id: M1WYG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1322246:BN4 RS16435
gene id: 1322246:BN4_RS16435
uniprot id: M1WUB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1322246:BN4 RS11555
gene id: 1322246:BN4_RS11555
uniprot id: M1WMF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1322246:BN4 RS08045
gene id: 1322246:BN4_RS08045
uniprot id: M1WM19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

1322246:BN4 RS00655
gene id: 1322246:BN4_RS00655
uniprot id: M1WL72
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1322246:BN4 RS03610
gene id: 1322246:BN4_RS03610
uniprot id: M1WJI2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1322246:BN4 RS14555
gene id: 1322246:BN4_RS14555
uniprot id: M1WN25
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1322246:BN4 RS12715
gene id: 1322246:BN4_RS12715
uniprot id: M1WXK0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1322246:BN4 RS15630
gene id: 1322246:BN4_RS15630
uniprot id: M1WSR2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1322246:BN4 RS10320
gene id: 1322246:BN4_RS10320
uniprot id: M1WKB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

1322246:BN4 RS01350
gene id: 1322246:BN4_RS01350
uniprot id: M1WLA0
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1322246:BN4 RS00280
gene id: 1322246:BN4_RS00280
uniprot id: M1WPT9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1322246:BN4 RS04955
gene id: 1322246:BN4_RS04955
uniprot id: M1WRB3
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1322246:BN4 RS09695
gene id: 1322246:BN4_RS09695
uniprot id: M1WWJ4
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1322246:BN4 RS04475
gene id: 1322246:BN4_RS04475
uniprot id: M1WJL6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1322246:BN4 RS12910
gene id: 1322246:BN4_RS12910
uniprot id: M1WXN0
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1322246:BN4 RS08495
gene id: 1322246:BN4_RS08495
uniprot id: M1WQG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1322246:BN4 RS02535
gene id: 1322246:BN4_RS02535
uniprot id: M1WLE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1322246:BN4 RS15655
gene id: 1322246:BN4_RS15655
uniprot id: M1WSR6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1322246:BN4 RS11135
gene id: 1322246:BN4_RS11135
uniprot id: M1WTC8
names: Similarity
messages: Belongs to the ParB family.

1322246:BN4 RS02665
gene id: 1322246:BN4_RS02665
uniprot id: M1WUQ6
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS00690
gene id: 1322246:BN4_RS00690
uniprot id: M1WPZ5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1322246:BN4 RS04150
gene id: 1322246:BN4_RS04150
uniprot id: M1WV01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1322246:BN4 RS00130
gene id: 1322246:BN4_RS00130
uniprot id: M1WJ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1322246:BN4 RS15975
gene id: 1322246:BN4_RS15975
uniprot id: M1WYL2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1322246:BN4 RS12615
gene id: 1322246:BN4_RS12615
uniprot id: M1WRT0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1322246:BN4 RS12390
gene id: 1322246:BN4_RS12390
uniprot id: M1WRQ3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1322246:BN4 RS04460
gene id: 1322246:BN4_RS04460
uniprot id: M1WV20
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1322246:BN4 RS11545
gene id: 1322246:BN4_RS11545
uniprot id: M1WX61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1322246:BN4 RS06675
gene id: 1322246:BN4_RS06675
uniprot id: M1WRW7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1322246:BN4 RS15255
gene id: 1322246:BN4_RS15255
uniprot id: M1WNB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1322246:BN4 RS09665
gene id: 1322246:BN4_RS09665
uniprot id: M1WSX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1322246:BN4 RS05275
gene id: 1322246:BN4_RS05275
uniprot id: M1WJQ0
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1322246:BN4 RS04020
gene id: 1322246:BN4_RS04020
uniprot id: M1WJJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1322246:BN4 RS01190
gene id: 1322246:BN4_RS01190
uniprot id: M1WQ47
names: Similarity
messages: Belongs to the bacterial glucokinase family.

1322246:BN4 RS00125
gene id: 1322246:BN4_RS00125
uniprot id: M1WL51
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1322246:BN4 RS07385
gene id: 1322246:BN4_RS07385
uniprot id: M1WLZ2
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS01595
gene id: 1322246:BN4_RS01595
uniprot id: M1WLA8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1322246:BN4 RS15855
gene id: 1322246:BN4_RS15855
uniprot id: M1WSV1
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1322246:BN4 RS14150
gene id: 1322246:BN4_RS14150
uniprot id: M1WY09
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS13070
gene id: 1322246:BN4_RS13070
uniprot id: M1WKM0
names: Similarity
messages: Belongs to the DDAH family.

1322246:BN4 RS05015
gene id: 1322246:BN4_RS05015
uniprot id: M1WLP6
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1322246:BN4 RS00090
gene id: 1322246:BN4_RS00090
uniprot id: M1WUF5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS02060
gene id: 1322246:BN4_RS02060
uniprot id: M1WLC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

1322246:BN4 RS08470
gene id: 1322246:BN4_RS08470
uniprot id: M1WQF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1322246:BN4 RS16595
gene id: 1322246:BN4_RS16595
uniprot id: M1WL10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1322246:BN4 RS10055
gene id: 1322246:BN4_RS10055
uniprot id: M1WM99
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS15665
gene id: 1322246:BN4_RS15665
uniprot id: M1WKX3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1322246:BN4 RS02735
gene id: 1322246:BN4_RS02735
uniprot id: M1WUQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS04335
gene id: 1322246:BN4_RS04335
uniprot id: M1WV12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1322246:BN4 RS16645
gene id: 1322246:BN4_RS16645
uniprot id: M1WL12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1322246:BN4 RS13690
gene id: 1322246:BN4_RS13690
uniprot id: M1WS45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1322246:BN4 RS12360
gene id: 1322246:BN4_RS12360
uniprot id: M1WRP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1322246:BN4 RS16855
gene id: 1322246:BN4_RS16855
uniprot id: M1WUD2
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS06970
gene id: 1322246:BN4_RS06970
uniprot id: M1WVN4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1322246:BN4 RS12685
gene id: 1322246:BN4_RS12685
uniprot id: M1WXJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1322246:BN4 RS02495
gene id: 1322246:BN4_RS02495
uniprot id: M1WQI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1322246:BN4 RS04620
gene id: 1322246:BN4_RS04620
uniprot id: M1WJM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS05330
gene id: 1322246:BN4_RS05330
uniprot id: M1WRG6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1322246:BN4 RS11610
gene id: 1322246:BN4_RS11610
uniprot id: M1WX68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1322246:BN4 RS09555
gene id: 1322246:BN4_RS09555
uniprot id: M1WM80
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1322246:BN4 RS01130
gene id: 1322246:BN4_RS01130
uniprot id: M1WL91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1322246:BN4 RS08480
gene id: 1322246:BN4_RS08480
uniprot id: M1WK38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1322246:BN4 RS16705
gene id: 1322246:BN4_RS16705
uniprot id: M1WYS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1322246:BN4 RS09170
gene id: 1322246:BN4_RS09170
uniprot id: M1WWC5
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS13595
gene id: 1322246:BN4_RS13595
uniprot id: M1WKP1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1322246:BN4 RS07500
gene id: 1322246:BN4_RS07500
uniprot id: M1WQ20
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1322246:BN4 RS02860
gene id: 1322246:BN4_RS02860
uniprot id: M1WUR4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS04330
gene id: 1322246:BN4_RS04330
uniprot id: M1WR36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1322246:BN4 RS13320
gene id: 1322246:BN4_RS13320
uniprot id: M1WTU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1322246:BN4 RS07415
gene id: 1322246:BN4_RS07415
uniprot id: M1WJY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

1322246:BN4 RS07765
gene id: 1322246:BN4_RS07765
uniprot id: M1WK10
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

1322246:BN4 RS11395
gene id: 1322246:BN4_RS11395
uniprot id: M1WRF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1322246:BN4 RS08120
gene id: 1322246:BN4_RS08120
uniprot id: M1WM23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1322246:BN4 RS08475
gene id: 1322246:BN4_RS08475
uniprot id: M1WM37
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS02520
gene id: 1322246:BN4_RS02520
uniprot id: M1WQI7
names: Similarity
messages: Belongs to the aspartokinase family.

1322246:BN4 RS02285
gene id: 1322246:BN4_RS02285
uniprot id: M1WJC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1322246:BN4 RS15350
gene id: 1322246:BN4_RS15350
uniprot id: M1WSN1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1322246:BN4 RS13120
gene id: 1322246:BN4_RS13120
uniprot id: M1WKM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS04145
gene id: 1322246:BN4_RS04145
uniprot id: M1WR22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1322246:BN4 RS00665
gene id: 1322246:BN4_RS00665
uniprot id: M1WPZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS04375
gene id: 1322246:BN4_RS04375
uniprot id: M1WJL2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1322246:BN4 RS16605
gene id: 1322246:BN4_RS16605
uniprot id: M1WYR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1322246:BN4 RS00070
gene id: 1322246:BN4_RS00070
uniprot id: M1WMW7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS08690
gene id: 1322246:BN4_RS08690
uniprot id: M1WSM2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1322246:BN4 RS14410
gene id: 1322246:BN4_RS14410
uniprot id: M1WN07
names: Similarity
messages: Belongs to the catalase family.

1322246:BN4 RS11380
gene id: 1322246:BN4_RS11380
uniprot id: M1WKF3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1322246:BN4 RS09140
gene id: 1322246:BN4_RS09140
uniprot id: M1WWC3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1322246:BN4 RS04240
gene id: 1322246:BN4_RS04240
uniprot id: M1WP57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1322246:BN4 RS14210
gene id: 1322246:BN4_RS14210
uniprot id: M1WKR5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1322246:BN4 RS07075
gene id: 1322246:BN4_RS07075
uniprot id: M1WVP0
names: Similarity
messages: Belongs to the peptidase A31 family.

1322246:BN4 RS08485
gene id: 1322246:BN4_RS08485
uniprot id: M1WSK1
names: Similarity
messages: Belongs to the UPF0102 family.

1322246:BN4 RS16300
gene id: 1322246:BN4_RS16300
uniprot id: M1WNP0
names: Similarity
messages: Belongs to the RemA family.

1322246:BN4 RS15485
gene id: 1322246:BN4_RS15485
uniprot id: M1WYF4
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS15815
gene id: 1322246:BN4_RS15815
uniprot id: M1WKX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1322246:BN4 RS09125
gene id: 1322246:BN4_RS09125
uniprot id: M1WM63
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1322246:BN4 RS05430
gene id: 1322246:BN4_RS05430
uniprot id: M1WVB9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1322246:BN4 RS05765
gene id: 1322246:BN4_RS05765
uniprot id: M1WVF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS16825
gene id: 1322246:BN4_RS16825
uniprot id: M1WL19
names: Similarity
messages: Belongs to the Ahb/Nir family.

1322246:BN4 RS08685
gene id: 1322246:BN4_RS08685
uniprot id: M1WK46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS04430
gene id: 1322246:BN4_RS04430
uniprot id: M1WR45
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS10090
gene id: 1322246:BN4_RS10090
uniprot id: M1WT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1322246:BN4 RS14590
gene id: 1322246:BN4_RS14590
uniprot id: M1WY53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1322246:BN4 RS02710
gene id: 1322246:BN4_RS02710
uniprot id: M1WQL5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1322246:BN4 RS05825
gene id: 1322246:BN4_RS05825
uniprot id: M1WLT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS08315
gene id: 1322246:BN4_RS08315
uniprot id: M1WW36
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS10865
gene id: 1322246:BN4_RS10865
uniprot id: M1WKD2
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1322246:BN4 RS09925
gene id: 1322246:BN4_RS09925
uniprot id: M1WK95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS16870
gene id: 1322246:BN4_RS16870
uniprot id: M1WNT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1322246:BN4 RS05445
gene id: 1322246:BN4_RS05445
uniprot id: M1WLR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1322246:BN4 RS16910
gene id: 1322246:BN4_RS16910
uniprot id: M1WYU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1322246:BN4 RS00825
gene id: 1322246:BN4_RS00825
uniprot id: M1WL79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1322246:BN4 RS03435
gene id: 1322246:BN4_RS03435
uniprot id: M1WLI1
names: Caution
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS02590
gene id: 1322246:BN4_RS02590
uniprot id: M1WQJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1322246:BN4 RS05150
gene id: 1322246:BN4_RS05150
uniprot id: M1WV91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1322246:BN4 RS14000
gene id: 1322246:BN4_RS14000
uniprot id: M1WS77
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1322246:BN4 RS15615
gene id: 1322246:BN4_RS15615
uniprot id: M1WKX1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1322246:BN4 RS05350
gene id: 1322246:BN4_RS05350
uniprot id: M1WJQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1322246:BN4 RS08965
gene id: 1322246:BN4_RS08965
uniprot id: M1WSQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1322246:BN4 RS00420
gene id: 1322246:BN4_RS00420
uniprot id: M1WPV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1322246:BN4 RS07985
gene id: 1322246:BN4_RS07985
uniprot id: M1WSD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1322246:BN4 RS16810
gene id: 1322246:BN4_RS16810
uniprot id: M1WT33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1322246:BN4 RS11475
gene id: 1322246:BN4_RS11475
uniprot id: M1WMF6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1322246:BN4 RS14955
gene id: 1322246:BN4_RS14955
uniprot id: M1WU39
names: Similarity
messages: Belongs to the leucine-binding protein family.

1322246:BN4 RS13945
gene id: 1322246:BN4_RS13945
uniprot id: M1WXY5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1322246:BN4 RS13290
gene id: 1322246:BN4_RS13290
uniprot id: M1WMQ4
names: Similarity
messages: Belongs to the UPF0751 family.

1322246:BN4 RS02790
gene id: 1322246:BN4_RS02790
uniprot id: M1WNT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1322246:BN4 RS00085
gene id: 1322246:BN4_RS00085
uniprot id: M1WPR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1322246:BN4 RS07170
gene id: 1322246:BN4_RS07170
uniprot id: M1WVP9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1322246:BN4 RS13525
gene id: 1322246:BN4_RS13525
uniprot id: M1WTV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1322246:BN4 RS01820
gene id: 1322246:BN4_RS01820
uniprot id: M1WLB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1322246:BN4 RS08780
gene id: 1322246:BN4_RS08780
uniprot id: M1WM49
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

1322246:BN4 RS16730
gene id: 1322246:BN4_RS16730
uniprot id: M1WYT0
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1322246:BN4 RS08510
gene id: 1322246:BN4_RS08510
uniprot id: M1WSK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1322246:BN4 RS05130
gene id: 1322246:BN4_RS05130
uniprot id: M1WPC7
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS07260
gene id: 1322246:BN4_RS07260
uniprot id: M1WJY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1322246:BN4 RS11210
gene id: 1322246:BN4_RS11210
uniprot id: M1WRC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

1322246:BN4 RS17270
gene id: 1322246:BN4_RS17270
uniprot id: M1WKJ7
names: Subcellular Location Annotation
messages: Cell inner membrane

1322246:BN4 RS04805
gene id: 1322246:BN4_RS04805
uniprot id: M1WLN7
names: Similarity
messages: Belongs to the universal stress protein A family.

1322246:BN4 RS03345
gene id: 1322246:BN4_RS03345
uniprot id: M1WNZ3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS07300
gene id: 1322246:BN4_RS07300
uniprot id: M1WVR1
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS05380
gene id: 1322246:BN4_RS05380
uniprot id: M1WVB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1322246:BN4 RS06035
gene id: 1322246:BN4_RS06035
uniprot id: M1WVH0
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1322246:BN4 RS16245
gene id: 1322246:BN4_RS16245
uniprot id: M1WUA8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1322246:BN4 RS12690
gene id: 1322246:BN4_RS12690
uniprot id: M1WRT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1322246:BN4 RS05110
gene id: 1322246:BN4_RS05110
uniprot id: M1WLQ0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1322246:BN4 RS14645
gene id: 1322246:BN4_RS14645
uniprot id: M1WSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS02265
gene id: 1322246:BN4_RS02265
uniprot id: M1WQF2
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS01505
gene id: 1322246:BN4_RS01505
uniprot id: M1WNE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS02750
gene id: 1322246:BN4_RS02750
uniprot id: M1WJE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1322246:BN4 RS12680
gene id: 1322246:BN4_RS12680
uniprot id: M1WTN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1322246:BN4 RS08230
gene id: 1322246:BN4_RS08230
uniprot id: M1WK28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1322246:BN4 RS04085
gene id: 1322246:BN4_RS04085
uniprot id: M1WP46
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS00065
gene id: 1322246:BN4_RS00065
uniprot id: M1WUF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1322246:BN4 RS09520
gene id: 1322246:BN4_RS09520
uniprot id: M1WWH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1322246:BN4 RS17180
gene id: 1322246:BN4_RS17180
uniprot id: M1WK48
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1322246:BN4 RS02685
gene id: 1322246:BN4_RS02685
uniprot id: M1WQL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1322246:BN4 RS15140
gene id: 1322246:BN4_RS15140
uniprot id: M1WSK2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS11935
gene id: 1322246:BN4_RS11935
uniprot id: M1WRK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS01630
gene id: 1322246:BN4_RS01630
uniprot id: M1WQ80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1322246:BN4 RS07480
gene id: 1322246:BN4_RS07480
uniprot id: M1WQ16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1322246:BN4 RS07180
gene id: 1322246:BN4_RS07180
uniprot id: M1WLY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1322246:BN4 RS01090
gene id: 1322246:BN4_RS01090
uniprot id: M1WQ39
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS05485
gene id: 1322246:BN4_RS05485
uniprot id: M1WVC4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1322246:BN4 RS14115
gene id: 1322246:BN4_RS14115
uniprot id: M1WKR1
names: Similarity
messages: Belongs to the UPF0758 family.

1322246:BN4 RS01675
gene id: 1322246:BN4_RS01675
uniprot id: M1WJA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1322246:BN4 RS06475
gene id: 1322246:BN4_RS06475
uniprot id: M1WPR1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1322246:BN4 RS13735
gene id: 1322246:BN4_RS13735
uniprot id: M1WKP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1322246:BN4 RS16050
gene id: 1322246:BN4_RS16050
uniprot id: M1WKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS10030
gene id: 1322246:BN4_RS10030
uniprot id: M1WM98
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS00415
gene id: 1322246:BN4_RS00415
uniprot id: M1WJ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1322246:BN4 RS11635
gene id: 1322246:BN4_RS11635
uniprot id: M1WX70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS15505
gene id: 1322246:BN4_RS15505
uniprot id: M1WU77
names: Similarity
messages: Belongs to the peptidase M18 family.

1322246:BN4 RS01195
gene id: 1322246:BN4_RS01195
uniprot id: M1WUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS12970
gene id: 1322246:BN4_RS12970
uniprot id: M1WTQ8
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1322246:BN4 RS16565
gene id: 1322246:BN4_RS16565
uniprot id: M1WNR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1322246:BN4 RS16130
gene id: 1322246:BN4_RS16130
uniprot id: M1WYM6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1322246:BN4 RS04450
gene id: 1322246:BN4_RS04450
uniprot id: M1WJL5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1322246:BN4 RS01390
gene id: 1322246:BN4_RS01390
uniprot id: M1WUK7
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS04815
gene id: 1322246:BN4_RS04815
uniprot id: M1WR92
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

1322246:BN4 RS06880
gene id: 1322246:BN4_RS06880
uniprot id: M1WRY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS08500
gene id: 1322246:BN4_RS08500
uniprot id: M1WM38
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1322246:BN4 RS16660
gene id: 1322246:BN4_RS16660
uniprot id: M1WT16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1322246:BN4 RS03175
gene id: 1322246:BN4_RS03175
uniprot id: M1WLH1
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS04905
gene id: 1322246:BN4_RS04905
uniprot id: M1WRA5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1322246:BN4 RS04445
gene id: 1322246:BN4_RS04445
uniprot id: M1WLM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1322246:BN4 RS16720
gene id: 1322246:BN4_RS16720
uniprot id: M1WL15
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1322246:BN4 RS00365
gene id: 1322246:BN4_RS00365
uniprot id: M1WJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1322246:BN4 RS01265
gene id: 1322246:BN4_RS01265
uniprot id: M1WUK2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1322246:BN4 RS10125
gene id: 1322246:BN4_RS10125
uniprot id: M1WQY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1322246:BN4 RS05095
gene id: 1322246:BN4_RS05095
uniprot id: M1WRD5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1322246:BN4 RS02530
gene id: 1322246:BN4_RS02530
uniprot id: M1WNQ7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1322246:BN4 RS16795
gene id: 1322246:BN4_RS16795
uniprot id: M1WL18
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1322246:BN4 RS07805
gene id: 1322246:BN4_RS07805
uniprot id: M1WQ62
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1322246:BN4 RS01815
gene id: 1322246:BN4_RS01815
uniprot id: M1WNH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1322246:BN4 RS10210
gene id: 1322246:BN4_RS10210
uniprot id: M1WKA6
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS08340
gene id: 1322246:BN4_RS08340
uniprot id: M1WW39
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1322246:BN4 RS04055
gene id: 1322246:BN4_RS04055
uniprot id: M1WUZ5
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS13885
gene id: 1322246:BN4_RS13885
uniprot id: M1WKQ2
names: Similarity
messages: Belongs to the MlaA family.

1322246:BN4 RS01415
gene id: 1322246:BN4_RS01415
uniprot id: M1WUK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1322246:BN4 RS16430
gene id: 1322246:BN4_RS16430
uniprot id: M1WL04
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1322246:BN4 RS14945
gene id: 1322246:BN4_RS14945
uniprot id: M1WN70
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS03055
gene id: 1322246:BN4_RS03055
uniprot id: M1WLG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1322246:BN4 RS10195
gene id: 1322246:BN4_RS10195
uniprot id: M1WWQ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1322246:BN4 RS08810
gene id: 1322246:BN4_RS08810
uniprot id: M1WM50
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS15605
gene id: 1322246:BN4_RS15605
uniprot id: M1WSQ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS07485
gene id: 1322246:BN4_RS07485
uniprot id: M1WLZ6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1322246:BN4 RS08570
gene id: 1322246:BN4_RS08570
uniprot id: M1WQG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1322246:BN4 RS09635
gene id: 1322246:BN4_RS09635
uniprot id: M1WK84
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1322246:BN4 RS07450
gene id: 1322246:BN4_RS07450
uniprot id: M1WVS9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS00815
gene id: 1322246:BN4_RS00815
uniprot id: M1WUI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1322246:BN4 RS17220
gene id: 1322246:BN4_RS17220
uniprot id: M1WTA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1322246:BN4 RS02570
gene id: 1322246:BN4_RS02570
uniprot id: M1WUQ2
names: Function
names: Similarity
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.

1322246:BN4 RS00615
gene id: 1322246:BN4_RS00615
uniprot id: M1WPY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1322246:BN4 RS16125
gene id: 1322246:BN4_RS16125
uniprot id: M1WUA3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1322246:BN4 RS16075
gene id: 1322246:BN4_RS16075
uniprot id: M1WKY9
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

1322246:BN4 RS13850
gene id: 1322246:BN4_RS13850
uniprot id: M1WS62
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1322246:BN4 RS00920
gene id: 1322246:BN4_RS00920
uniprot id: M1WN90
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1322246:BN4 RS01355
gene id: 1322246:BN4_RS01355
uniprot id: M1WJ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1322246:BN4 RS13250
gene id: 1322246:BN4_RS13250
uniprot id: M1WTT3
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS14445
gene id: 1322246:BN4_RS14445
uniprot id: M1WU14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1322246:BN4 RS12830
gene id: 1322246:BN4_RS12830
uniprot id: M1WRV4
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS15950
gene id: 1322246:BN4_RS15950
uniprot id: M1WYL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1322246:BN4 RS05565
gene id: 1322246:BN4_RS05565
uniprot id: M1WVD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1322246:BN4 RS12370
gene id: 1322246:BN4_RS12370
uniprot id: M1WKJ3
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1322246:BN4 RS10830
gene id: 1322246:BN4_RS10830
uniprot id: M1WR90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1322246:BN4 RS09045
gene id: 1322246:BN4_RS09045
uniprot id: M1WWB0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1322246:BN4 RS08380
gene id: 1322246:BN4_RS08380
uniprot id: M1WK34
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1322246:BN4 RS17295
gene id: 1322246:BN4_RS17295
uniprot id: M1WXU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1322246:BN4 RS16135
gene id: 1322246:BN4_RS16135
uniprot id: M1WSX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatB family.
messages: Cell inner membrane

1322246:BN4 RS02295
gene id: 1322246:BN4_RS02295
uniprot id: M1WUP1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1322246:BN4 RS01855
gene id: 1322246:BN4_RS01855
uniprot id: M1WUM4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1322246:BN4 RS04135
gene id: 1322246:BN4_RS04135
uniprot id: M1WLL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1322246:BN4 RS03870
gene id: 1322246:BN4_RS03870
uniprot id: M1WJJ2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1322246:BN4 RS14530
gene id: 1322246:BN4_RS14530
uniprot id: M1WSD3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1322246:BN4 RS01765
gene id: 1322246:BN4_RS01765
uniprot id: M1WNH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1322246:BN4 RS04370
gene id: 1322246:BN4_RS04370
uniprot id: M1WLL9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1322246:BN4 RS14870
gene id: 1322246:BN4_RS14870
uniprot id: M1WSG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1322246:BN4 RS05140
gene id: 1322246:BN4_RS05140
uniprot id: M1WJP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1322246:BN4 RS07565
gene id: 1322246:BN4_RS07565
uniprot id: M1WJZ6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1322246:BN4 RS05135
gene id: 1322246:BN4_RS05135
uniprot id: M1WLQ1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1322246:BN4 RS10805
gene id: 1322246:BN4_RS10805
uniprot id: M1WR87
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1322246:BN4 RS16700
gene id: 1322246:BN4_RS16700
uniprot id: M1WUC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1322246:BN4 RS02175
gene id: 1322246:BN4_RS02175
uniprot id: M1WLD1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1322246:BN4 RS07515
gene id: 1322246:BN4_RS07515
uniprot id: M1WS63
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS14195
gene id: 1322246:BN4_RS14195
uniprot id: M1WY15
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1322246:BN4 RS05890
gene id: 1322246:BN4_RS05890
uniprot id: M1WVG1
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1322246:BN4 RS00710
gene id: 1322246:BN4_RS00710
uniprot id: M1WJ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS08520
gene id: 1322246:BN4_RS08520
uniprot id: M1WQG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1322246:BN4 RS02675
gene id: 1322246:BN4_RS02675
uniprot id: M1WLF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1322246:BN4 RS04650
gene id: 1322246:BN4_RS04650
uniprot id: M1WR72
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1322246:BN4 RS16305
gene id: 1322246:BN4_RS16305
uniprot id: M1WKZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1322246:BN4 RS08925
gene id: 1322246:BN4_RS08925
uniprot id: M1WQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1322246:BN4 RS10380
gene id: 1322246:BN4_RS10380
uniprot id: M1WR21
names: Function
names: Similarity
messages: Belongs to the rhamnosyl O-methyltransferase family.
messages: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).

1322246:BN4 RS01060
gene id: 1322246:BN4_RS01060
uniprot id: M1WJ82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1322246:BN4 RS13215
gene id: 1322246:BN4_RS13215
uniprot id: M1WKM6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1322246:BN4 RS07775
gene id: 1322246:BN4_RS07775
uniprot id: M1WVX1
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1322246:BN4 RS06530
gene id: 1322246:BN4_RS06530
uniprot id: M1WJV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1322246:BN4 RS02830
gene id: 1322246:BN4_RS02830
uniprot id: M1WQN2
names: Similarity
messages: Belongs to the sigma-54 factor family.

1322246:BN4 RS02100
gene id: 1322246:BN4_RS02100
uniprot id: M1WUN4
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

1322246:BN4 RS09580
gene id: 1322246:BN4_RS09580
uniprot id: M1WM81
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS00390
gene id: 1322246:BN4_RS00390
uniprot id: M1WJ56
names: Similarity
messages: Belongs to the glutamate synthase family.

1322246:BN4 RS13730
gene id: 1322246:BN4_RS13730
uniprot id: M1WMU2
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1322246:BN4 RS01260
gene id: 1322246:BN4_RS01260
uniprot id: M1WQ54
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1322246:BN4 RS08700
gene id: 1322246:BN4_RS08700
uniprot id: M1WQI1
names: Subunit
messages: Homodimer.

1322246:BN4 RS12110
gene id: 1322246:BN4_RS12110
uniprot id: M1WTJ7
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1322246:BN4 RS03090
gene id: 1322246:BN4_RS03090
uniprot id: M1WUS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS05180
gene id: 1322246:BN4_RS05180
uniprot id: M1WLQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1322246:BN4 RS08085
gene id: 1322246:BN4_RS08085
uniprot id: M1WW06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1322246:BN4 RS03770
gene id: 1322246:BN4_RS03770
uniprot id: M1WUX8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS02690
gene id: 1322246:BN4_RS02690
uniprot id: M1WUQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1322246:BN4 RS09800
gene id: 1322246:BN4_RS09800
uniprot id: M1WWK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS04305
gene id: 1322246:BN4_RS04305
uniprot id: M1WR33
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1322246:BN4 RS08260
gene id: 1322246:BN4_RS08260
uniprot id: M1WSH7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1322246:BN4 RS12105
gene id: 1322246:BN4_RS12105
uniprot id: M1WKI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

1322246:BN4 RS16685
gene id: 1322246:BN4_RS16685
uniprot id: M1WT19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1322246:BN4 RS13205
gene id: 1322246:BN4_RS13205
uniprot id: M1WS01
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1322246:BN4 RS09435
gene id: 1322246:BN4_RS09435
uniprot id: M1WK76
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1322246:BN4 RS03965
gene id: 1322246:BN4_RS03965
uniprot id: M1WLK2
names: Similarity
messages: Belongs to the MEMO1 family.

1322246:BN4 RS00175
gene id: 1322246:BN4_RS00175
uniprot id: M1WL53
names: Similarity
messages: Belongs to the class-I fumarase family.

1322246:BN4 RS11365
gene id: 1322246:BN4_RS11365
uniprot id: M1WX40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1322246:BN4 RS14595
gene id: 1322246:BN4_RS14595
uniprot id: M1WSE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1322246:BN4 RS11805
gene id: 1322246:BN4_RS11805
uniprot id: M1WTH5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1322246:BN4 RS08795
gene id: 1322246:BN4_RS08795
uniprot id: M1WSN2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS12445
gene id: 1322246:BN4_RS12445
uniprot id: M1WMJ5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1322246:BN4 RS09430
gene id: 1322246:BN4_RS09430
uniprot id: M1WM75
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1322246:BN4 RS02545
gene id: 1322246:BN4_RS02545
uniprot id: M1WUQ1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1322246:BN4 RS15740
gene id: 1322246:BN4_RS15740
uniprot id: M1WKX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1322246:BN4 RS00805
gene id: 1322246:BN4_RS00805
uniprot id: M1WJ72
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1322246:BN4 RS04645
gene id: 1322246:BN4_RS04645
uniprot id: M1WJM3
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS12635
gene id: 1322246:BN4_RS12635
uniprot id: M1WXI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1322246:BN4 RS16750
gene id: 1322246:BN4_RS16750
uniprot id: M1WUC8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1322246:BN4 RS16310
gene id: 1322246:BN4_RS16310
uniprot id: M1WUB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1322246:BN4 RS15120
gene id: 1322246:BN4_RS15120
uniprot id: M1WN94
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1322246:BN4 RS08465
gene id: 1322246:BN4_RS08465
uniprot id: M1WW49
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS16370
gene id: 1322246:BN4_RS16370
uniprot id: M1WSY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1322246:BN4 RS02825
gene id: 1322246:BN4_RS02825
uniprot id: M1WJF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1322246:BN4 RS11560
gene id: 1322246:BN4_RS11560
uniprot id: M1WKG0
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS04290
gene id: 1322246:BN4_RS04290
uniprot id: M1WP60
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1322246:BN4 RS13655
gene id: 1322246:BN4_RS13655
uniprot id: M1WXV6
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS08270
gene id: 1322246:BN4_RS08270
uniprot id: M1WQD7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1322246:BN4 RS04275
gene id: 1322246:BN4_RS04275
uniprot id: M1WJK8
names: Similarity
messages: Belongs to the Skp family.

1322246:BN4 RS05555
gene id: 1322246:BN4_RS05555
uniprot id: M1WRJ8
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

1322246:BN4 RS05300
gene id: 1322246:BN4_RS05300
uniprot id: M1WJQ1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1322246:BN4 RS04115
gene id: 1322246:BN4_RS04115
uniprot id: M1WJK2
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS12425
gene id: 1322246:BN4_RS12425
uniprot id: M1WKJ5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1322246:BN4 RS11390
gene id: 1322246:BN4_RS11390
uniprot id: M1WX43
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1322246:BN4 RS12145
gene id: 1322246:BN4_RS12145
uniprot id: M1WRM5
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS01230
gene id: 1322246:BN4_RS01230
uniprot id: M1WJ89
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1322246:BN4 RS12240
gene id: 1322246:BN4_RS12240
uniprot id: M1WRN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1322246:BN4 RS12490
gene id: 1322246:BN4_RS12490
uniprot id: M1WRR4
names: Subcellular Location Annotation
messages: Cell inner membrane

1322246:BN4 RS03000
gene id: 1322246:BN4_RS03000
uniprot id: M1WLG4
names: Similarity
messages: Belongs to the class-I fumarase family.

1322246:BN4 RS11710
gene id: 1322246:BN4_RS11710
uniprot id: M1WTG7
names: Subcellular Location Annotation
messages: Nucleus

1322246:BN4 RS02445
gene id: 1322246:BN4_RS02445
uniprot id: M1WJD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1322246:BN4 RS03955
gene id: 1322246:BN4_RS03955
uniprot id: M1WUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1322246:BN4 RS15220
gene id: 1322246:BN4_RS15220
uniprot id: M1WKV6
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS14140
gene id: 1322246:BN4_RS14140
uniprot id: M1WKR2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1322246:BN4 RS03165
gene id: 1322246:BN4_RS03165
uniprot id: M1WUT6
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1322246:BN4 RS00970
gene id: 1322246:BN4_RS00970
uniprot id: M1WUJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1322246:BN4 RS09940
gene id: 1322246:BN4_RS09940
uniprot id: M1WQW1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1322246:BN4 RS15860
gene id: 1322246:BN4_RS15860
uniprot id: M1WNK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1322246:BN4 RS06045
gene id: 1322246:BN4_RS06045
uniprot id: M1WLT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1322246:BN4 RS15670
gene id: 1322246:BN4_RS15670
uniprot id: M1WU84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1322246:BN4 RS10150
gene id: 1322246:BN4_RS10150
uniprot id: M1WQY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1322246:BN4 RS09660
gene id: 1322246:BN4_RS09660
uniprot id: M1WK85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1322246:BN4 RS03320
gene id: 1322246:BN4_RS03320
uniprot id: M1WNZ1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1322246:BN4 RS14325
gene id: 1322246:BN4_RS14325
uniprot id: M1WMZ8
names: Similarity
messages: Belongs to the MipA/OmpV family.

1322246:BN4 RS02440
gene id: 1322246:BN4_RS02440
uniprot id: M1WLE1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1322246:BN4 RS16615
gene id: 1322246:BN4_RS16615
uniprot id: M1WNR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1322246:BN4 RS02995
gene id: 1322246:BN4_RS02995
uniprot id: M1WNV9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1322246:BN4 RS02095
gene id: 1322246:BN4_RS02095
uniprot id: M1WQD3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1322246:BN4 RS08505
gene id: 1322246:BN4_RS08505
uniprot id: M1WK39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1322246:BN4 RS02450
gene id: 1322246:BN4_RS02450
uniprot id: M1WQH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1322246:BN4 RS11035
gene id: 1322246:BN4_RS11035
uniprot id: M1WTC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

1322246:BN4 RS04325
gene id: 1322246:BN4_RS04325
uniprot id: M1WJL0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS15985
gene id: 1322246:BN4_RS15985
uniprot id: M1WNL2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1322246:BN4 RS03865
gene id: 1322246:BN4_RS03865
uniprot id: M1WLJ8
names: Similarity
messages: Belongs to the bacterial flagellin family.

1322246:BN4 RS03790
gene id: 1322246:BN4_RS03790
uniprot id: M1WQZ0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1322246:BN4 RS12810
gene id: 1322246:BN4_RS12810
uniprot id: M1WKL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1322246:BN4 RS16395
gene id: 1322246:BN4_RS16395
uniprot id: M1WSZ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS12440
gene id: 1322246:BN4_RS12440
uniprot id: M1WRR0
names: Similarity
messages: Belongs to the UPF0434 family.

1322246:BN4 RS00680
gene id: 1322246:BN4_RS00680
uniprot id: M1WL73
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS00735
gene id: 1322246:BN4_RS00735
uniprot id: M1WJ69
names: Similarity
messages: Belongs to the AOR/FOR family.

1322246:BN4 RS16100
gene id: 1322246:BN4_RS16100
uniprot id: M1WUA2
names: Similarity
messages: Belongs to the leucine-binding protein family.

1322246:BN4 RS15365
gene id: 1322246:BN4_RS15365
uniprot id: M1WU70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1322246:BN4 RS13560
gene id: 1322246:BN4_RS13560
uniprot id: M1WXU6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1322246:BN4 RS09515
gene id: 1322246:BN4_RS09515
uniprot id: M1WSV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS15760
gene id: 1322246:BN4_RS15760
uniprot id: M1WNI2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1322246:BN4 RS05525
gene id: 1322246:BN4_RS05525
uniprot id: M1WLR7
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

1322246:BN4 RS04280
gene id: 1322246:BN4_RS04280
uniprot id: M1WR31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1322246:BN4 RS14185
gene id: 1322246:BN4_RS14185
uniprot id: M1WKR4
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS08605
gene id: 1322246:BN4_RS08605
uniprot id: M1WK43
names: Similarity
messages: Belongs to the Ahb/Nir family.

1322246:BN4 RS06260
gene id: 1322246:BN4_RS06260
uniprot id: M1WVI6
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1322246:BN4 RS02645
gene id: 1322246:BN4_RS02645
uniprot id: M1WNS3
names: Similarity
messages: Belongs to the peptidase S41A family.

1322246:BN4 RS17310
gene id: 1322246:BN4_RS17310
uniprot id: M1WKQ3
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS06240
gene id: 1322246:BN4_RS06240
uniprot id: M1WPN8
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS09235
gene id: 1322246:BN4_RS09235
uniprot id: M1WK68
names: Similarity
messages: Belongs to the YciI family.

1322246:BN4 RS04125
gene id: 1322246:BN4_RS04125
uniprot id: M1WV00
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS13925
gene id: 1322246:BN4_RS13925
uniprot id: M1WS69
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1322246:BN4 RS16105
gene id: 1322246:BN4_RS16105
uniprot id: M1WYM3
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS11005
gene id: 1322246:BN4_RS11005
uniprot id: M1WMD7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1322246:BN4 RS05440
gene id: 1322246:BN4_RS05440
uniprot id: M1WPE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1322246:BN4 RS07265
gene id: 1322246:BN4_RS07265
uniprot id: M1WS24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1322246:BN4 RS03600
gene id: 1322246:BN4_RS03600
uniprot id: M1WP12
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1322246:BN4 RS06100
gene id: 1322246:BN4_RS06100
uniprot id: M1WVH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1322246:BN4 RS12665
gene id: 1322246:BN4_RS12665
uniprot id: M1WRT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1322246:BN4 RS00100
gene id: 1322246:BN4_RS00100
uniprot id: M1WL50
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1322246:BN4 RS00695
gene id: 1322246:BN4_RS00695
uniprot id: M1WUH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS12410
gene id: 1322246:BN4_RS12410
uniprot id: M1WXF5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1322246:BN4 RS01850
gene id: 1322246:BN4_RS01850
uniprot id: M1WQA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1322246:BN4 RS01835
gene id: 1322246:BN4_RS01835
uniprot id: M1WNH9
names: Similarity
messages: Belongs to the LOG family.

1322246:BN4 RS11930
gene id: 1322246:BN4_RS11930
uniprot id: M1WX97
names: Similarity
messages: Belongs to the P(II) protein family.

1322246:BN4 RS05865
gene id: 1322246:BN4_RS05865
uniprot id: M1WRP2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1322246:BN4 RS10105
gene id: 1322246:BN4_RS10105
uniprot id: M1WMA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1322246:BN4 RS03035
gene id: 1322246:BN4_RS03035
uniprot id: M1WJF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1322246:BN4 RS09035
gene id: 1322246:BN4_RS09035
uniprot id: M1WK60
names: Similarity
messages: Belongs to the leucine-binding protein family.

1322246:BN4 RS10120
gene id: 1322246:BN4_RS10120
uniprot id: M1WWP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1322246:BN4 RS16560
gene id: 1322246:BN4_RS16560
uniprot id: M1WT04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1322246:BN4 RS13360
gene id: 1322246:BN4_RS13360
uniprot id: M1WS17
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1322246:BN4 RS01270
gene id: 1322246:BN4_RS01270
uniprot id: M1WNC4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1322246:BN4 RS05615
gene id: 1322246:BN4_RS05615
uniprot id: M1WRK5
names: Similarity
messages: Belongs to the ros/MucR family.

1322246:BN4 RS16675
gene id: 1322246:BN4_RS16675
uniprot id: M1WUC5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1322246:BN4 RS02525
gene id: 1322246:BN4_RS02525
uniprot id: M1WUQ0
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1322246:BN4 RS10705
gene id: 1322246:BN4_RS10705
uniprot id: M1WR66
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1322246:BN4 RS13775
gene id: 1322246:BN4_RS13775
uniprot id: M1WS54
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1322246:BN4 RS04665
gene id: 1322246:BN4_RS04665
uniprot id: M1WLN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1322246:BN4 RS07875
gene id: 1322246:BN4_RS07875
uniprot id: M1WVY3
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS01490
gene id: 1322246:BN4_RS01490
uniprot id: M1WJ99
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

1322246:BN4 RS16185
gene id: 1322246:BN4_RS16185
uniprot id: M1WSX6
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS14050
gene id: 1322246:BN4_RS14050
uniprot id: M1WS82
names: Similarity
messages: Belongs to the hemerythrin family.

1322246:BN4 RS12590
gene id: 1322246:BN4_RS12590
uniprot id: M1WRS6
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1322246:BN4 RS03010
gene id: 1322246:BN4_RS03010
uniprot id: M1WQQ5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1322246:BN4 RS01990
gene id: 1322246:BN4_RS01990
uniprot id: M1WQC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1322246:BN4 RS16695
gene id: 1322246:BN4_RS16695
uniprot id: M1WL14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1322246:BN4 RS16170
gene id: 1322246:BN4_RS16170
uniprot id: M1WKZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1322246:BN4 RS03690
gene id: 1322246:BN4_RS03690
uniprot id: M1WQY2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1322246:BN4 RS06590
gene id: 1322246:BN4_RS06590
uniprot id: M1WPS6
names: Similarity
messages: Belongs to the hemerythrin family.

1322246:BN4 RS08660
gene id: 1322246:BN4_RS08660
uniprot id: M1WK45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS10155
gene id: 1322246:BN4_RS10155
uniprot id: M1WMA3
names: Similarity
messages: Belongs to the glutamine synthetase family.

1322246:BN4 RS01285
gene id: 1322246:BN4_RS01285
uniprot id: M1WQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1322246:BN4 RS05260
gene id: 1322246:BN4_RS05260
uniprot id: M1WVA2
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS07110
gene id: 1322246:BN4_RS07110
uniprot id: M1WLY1
names: Similarity
messages: Belongs to the UPF0045 family.

1322246:BN4 RS01670
gene id: 1322246:BN4_RS01670
uniprot id: M1WLB1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS01375
gene id: 1322246:BN4_RS01375
uniprot id: M1WLA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

1322246:BN4 RS14570
gene id: 1322246:BN4_RS14570
uniprot id: M1WSD8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1322246:BN4 RS11875
gene id: 1322246:BN4_RS11875
uniprot id: M1WMH2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1322246:BN4 RS01360
gene id: 1322246:BN4_RS01360
uniprot id: M1WQ61
names: Similarity
messages: Belongs to the MotB family.

1322246:BN4 RS13725
gene id: 1322246:BN4_RS13725
uniprot id: M1WS48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1322246:BN4 RS03250
gene id: 1322246:BN4_RS03250
uniprot id: M1WQU2
names: Similarity
messages: Belongs to the transposase 7 family.

1322246:BN4 RS01785
gene id: 1322246:BN4_RS01785
uniprot id: M1WUM1
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS12540
gene id: 1322246:BN4_RS12540
uniprot id: M1WRS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1322246:BN4 RS04565
gene id: 1322246:BN4_RS04565
uniprot id: M1WLM7
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1322246:BN4 RS14575
gene id: 1322246:BN4_RS14575
uniprot id: M1WN28
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1322246:BN4 RS06850
gene id: 1322246:BN4_RS06850
uniprot id: M1WJW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1322246:BN4 RS12270
gene id: 1322246:BN4_RS12270
uniprot id: M1WMI8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1322246:BN4 RS14770
gene id: 1322246:BN4_RS14770
uniprot id: M1WSF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1322246:BN4 RS08625
gene id: 1322246:BN4_RS08625
uniprot id: M1WM43
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

1322246:BN4 RS08025
gene id: 1322246:BN4_RS08025
uniprot id: M1WM18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS01910
gene id: 1322246:BN4_RS01910
uniprot id: M1WJB5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1322246:BN4 RS09990
gene id: 1322246:BN4_RS09990
uniprot id: M1WWM8
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1322246:BN4 RS09160
gene id: 1322246:BN4_RS09160
uniprot id: M1WK65
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1322246:BN4 RS14030
gene id: 1322246:BN4_RS14030
uniprot id: M1WMW9
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1322246:BN4 RS17025
gene id: 1322246:BN4_RS17025
uniprot id: M1WR28
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS00510
gene id: 1322246:BN4_RS00510
uniprot id: M1WL67
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1322246:BN4 RS15360
gene id: 1322246:BN4_RS15360
uniprot id: M1WKW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1322246:BN4 RS11485
gene id: 1322246:BN4_RS11485
uniprot id: M1WTF3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1322246:BN4 RS05170
gene id: 1322246:BN4_RS05170
uniprot id: M1WV93
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1322246:BN4 RS07580
gene id: 1322246:BN4_RS07580
uniprot id: M1WM00
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS16155
gene id: 1322246:BN4_RS16155
uniprot id: M1WYM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1322246:BN4 RS16515
gene id: 1322246:BN4_RS16515
uniprot id: M1WL07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1322246:BN4 RS15190
gene id: 1322246:BN4_RS15190
uniprot id: M1WSL0
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1322246:BN4 RS10235
gene id: 1322246:BN4_RS10235
uniprot id: M1WKA7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1322246:BN4 RS02280
gene id: 1322246:BN4_RS02280
uniprot id: M1WLD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1322246:BN4 RS00170
gene id: 1322246:BN4_RS00170
uniprot id: M1WMX9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1322246:BN4 RS02065
gene id: 1322246:BN4_RS02065
uniprot id: M1WJC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

1322246:BN4 RS05645
gene id: 1322246:BN4_RS05645
uniprot id: M1WPG9
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS12210
gene id: 1322246:BN4_RS12210
uniprot id: M1WXD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1322246:BN4 RS01970
gene id: 1322246:BN4_RS01970
uniprot id: M1WUM9
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS12835
gene id: 1322246:BN4_RS12835
uniprot id: M1WML9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1322246:BN4 RS13170
gene id: 1322246:BN4_RS13170
uniprot id: M1WTS3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1322246:BN4 RS02385
gene id: 1322246:BN4_RS02385
uniprot id: M1WNN9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1322246:BN4 RS08775
gene id: 1322246:BN4_RS08775
uniprot id: M1WQI9
names: Similarity
messages: Belongs to the UPF0047 family.

1322246:BN4 RS03145
gene id: 1322246:BN4_RS03145
uniprot id: M1WNX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1322246:BN4 RS07145
gene id: 1322246:BN4_RS07145
uniprot id: M1WS09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS14110
gene id: 1322246:BN4_RS14110
uniprot id: M1WMX5
names: Similarity
messages: Belongs to the acylphosphatase family.

1322246:BN4 RS01180
gene id: 1322246:BN4_RS01180
uniprot id: M1WL93
names: Similarity
messages: Belongs to the MotB family.

1322246:BN4 RS07050
gene id: 1322246:BN4_RS07050
uniprot id: M1WVN7
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS15880
gene id: 1322246:BN4_RS15880
uniprot id: M1WSV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1322246:BN4 RS02085
gene id: 1322246:BN4_RS02085
uniprot id: M1WNK1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1322246:BN4 RS05795
gene id: 1322246:BN4_RS05795
uniprot id: M1WLS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS16640
gene id: 1322246:BN4_RS16640
uniprot id: M1WNS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1322246:BN4 RS13380
gene id: 1322246:BN4_RS13380
uniprot id: M1WXT3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS01110
gene id: 1322246:BN4_RS01110
uniprot id: M1WJ84
names: Similarity
messages: Belongs to the CutA family.

1322246:BN4 RS10260
gene id: 1322246:BN4_RS10260
uniprot id: M1WMA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1322246:BN4 RS05090
gene id: 1322246:BN4_RS05090
uniprot id: M1WJP2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1322246:BN4 RS05175
gene id: 1322246:BN4_RS05175
uniprot id: M1WPD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1322246:BN4 RS07935
gene id: 1322246:BN4_RS07935
uniprot id: M1WVY9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1322246:BN4 RS00760
gene id: 1322246:BN4_RS00760
uniprot id: M1WL76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

1322246:BN4 RS02500
gene id: 1322246:BN4_RS02500
uniprot id: M1WUP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1322246:BN4 RS07020
gene id: 1322246:BN4_RS07020
uniprot id: M1WRZ7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1322246:BN4 RS04400
gene id: 1322246:BN4_RS04400
uniprot id: M1WR43
names: Similarity
messages: Belongs to the hemerythrin family.

1322246:BN4 RS16805
gene id: 1322246:BN4_RS16805
uniprot id: M1WYT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1322246:BN4 RS08075
gene id: 1322246:BN4_RS08075
uniprot id: M1WK22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1322246:BN4 RS11440
gene id: 1322246:BN4_RS11440
uniprot id: M1WX51
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS02090
gene id: 1322246:BN4_RS02090
uniprot id: M1WLC8
names: Similarity
messages: Belongs to the peptidase S16 family.

1322246:BN4 RS08010
gene id: 1322246:BN4_RS08010
uniprot id: M1WSD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

1322246:BN4 RS08225
gene id: 1322246:BN4_RS08225
uniprot id: M1WM27
names: Similarity
messages: Belongs to the UPF0111 family.

1322246:BN4 RS03075
gene id: 1322246:BN4_RS03075
uniprot id: M1WNW7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1322246:BN4 RS14615
gene id: 1322246:BN4_RS14615
uniprot id: M1WU21
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1322246:BN4 RS09360
gene id: 1322246:BN4_RS09360
uniprot id: M1WK73
names: Similarity
messages: Belongs to the AOR/FOR family.

1322246:BN4 RS07340
gene id: 1322246:BN4_RS07340
uniprot id: M1WJY5
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS05185
gene id: 1322246:BN4_RS05185
uniprot id: M1WJP6
names: Similarity
messages: Belongs to the hemerythrin family.

1322246:BN4 RS08705
gene id: 1322246:BN4_RS08705
uniprot id: M1WM46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

1322246:BN4 RS07095
gene id: 1322246:BN4_RS07095
uniprot id: M1WS06
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

1322246:BN4 RS06460
gene id: 1322246:BN4_RS06460
uniprot id: M1WJU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS07785
gene id: 1322246:BN4_RS07785
uniprot id: M1WK11
names: Similarity
messages: Belongs to the glutamine synthetase family.

1322246:BN4 RS05045
gene id: 1322246:BN4_RS05045
uniprot id: M1WJP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1322246:BN4 RS09840
gene id: 1322246:BN4_RS09840
uniprot id: M1WK92
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1322246:BN4 RS15725
gene id: 1322246:BN4_RS15725
uniprot id: M1WYH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1322246:BN4 RS02745
gene id: 1322246:BN4_RS02745
uniprot id: M1WLF4
names: Similarity
messages: Belongs to the peptidase M20A family.

1322246:BN4 RS02970
gene id: 1322246:BN4_RS02970
uniprot id: M1WNV7
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS09180
gene id: 1322246:BN4_RS09180
uniprot id: M1WM65
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1322246:BN4 RS09005
gene id: 1322246:BN4_RS09005
uniprot id: M1WM58
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1322246:BN4 RS02505
gene id: 1322246:BN4_RS02505
uniprot id: M1WNQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS11025
gene id: 1322246:BN4_RS11025
uniprot id: M1WMD8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1322246:BN4 RS00555
gene id: 1322246:BN4_RS00555
uniprot id: M1WUH4
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1322246:BN4 RS12790
gene id: 1322246:BN4_RS12790
uniprot id: M1WKK9
names: Similarity
messages: Belongs to the peptidase S49 family.

1322246:BN4 RS10880
gene id: 1322246:BN4_RS10880
uniprot id: M1WR97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1322246:BN4 RS02720
gene id: 1322246:BN4_RS02720
uniprot id: M1WLF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1322246:BN4 RS15875
gene id: 1322246:BN4_RS15875
uniprot id: M1WYK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1322246:BN4 RS14665
gene id: 1322246:BN4_RS14665
uniprot id: M1WY61
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS13870
gene id: 1322246:BN4_RS13870
uniprot id: M1WXX6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1322246:BN4 RS04205
gene id: 1322246:BN4_RS04205
uniprot id: M1WP55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS01275
gene id: 1322246:BN4_RS01275
uniprot id: M1WL97
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1322246:BN4 RS02730
gene id: 1322246:BN4_RS02730
uniprot id: M1WQL8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

1322246:BN4 RS16590
gene id: 1322246:BN4_RS16590
uniprot id: M1WNR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1322246:BN4 RS06595
gene id: 1322246:BN4_RS06595
uniprot id: M1WLW2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1322246:BN4 RS03890
gene id: 1322246:BN4_RS03890
uniprot id: M1WLJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1322246:BN4 RS00430
gene id: 1322246:BN4_RS00430
uniprot id: M1WN23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1322246:BN4 RS07080
gene id: 1322246:BN4_RS07080
uniprot id: M1WPX3
names: Similarity
messages: Belongs to the HupF/HypC family.

1322246:BN4 RS00955
gene id: 1322246:BN4_RS00955
uniprot id: M1WL84
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1322246:BN4 RS16600
gene id: 1322246:BN4_RS16600
uniprot id: M1WUC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1322246:BN4 RS01255
gene id: 1322246:BN4_RS01255
uniprot id: M1WJ90
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1322246:BN4 RS05475
gene id: 1322246:BN4_RS05475
uniprot id: M1WJQ8
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS06135
gene id: 1322246:BN4_RS06135
uniprot id: M1WLU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1322246:BN4 RS07090
gene id: 1322246:BN4_RS07090
uniprot id: M1WJX5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1322246:BN4 RS06150
gene id: 1322246:BN4_RS06150
uniprot id: M1WJT7
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS12265
gene id: 1322246:BN4_RS12265
uniprot id: M1WRN7
names: Similarity
messages: Belongs to the DNA photolyase class-2 family.

1322246:BN4 RS15870
gene id: 1322246:BN4_RS15870
uniprot id: M1WU93
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1322246:BN4 RS08515
gene id: 1322246:BN4_RS08515
uniprot id: M1WW53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1322246:BN4 RS15215
gene id: 1322246:BN4_RS15215
uniprot id: M1WNA9
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS02490
gene id: 1322246:BN4_RS02490
uniprot id: M1WJD7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1322246:BN4 RS00075
gene id: 1322246:BN4_RS00075
uniprot id: M1WL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1322246:BN4 RS16145
gene id: 1322246:BN4_RS16145
uniprot id: M1WKZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1322246:BN4 RS01215
gene id: 1322246:BN4_RS01215
uniprot id: M1WUK0
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS10190
gene id: 1322246:BN4_RS10190
uniprot id: M1WT42
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1322246:BN4 RS13915
gene id: 1322246:BN4_RS13915
uniprot id: M1WTY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1322246:BN4 RS03395
gene id: 1322246:BN4_RS03395
uniprot id: M1WUV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS08540
gene id: 1322246:BN4_RS08540
uniprot id: M1WW55
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1322246:BN4 RS16880
gene id: 1322246:BN4_RS16880
uniprot id: M1WUD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1322246:BN4 RS06070
gene id: 1322246:BN4_RS06070
uniprot id: M1WJT3
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS04075
gene id: 1322246:BN4_RS04075
uniprot id: M1WR15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1322246:BN4 RS07140
gene id: 1322246:BN4_RS07140
uniprot id: M1WJX7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

1322246:BN4 RS00625
gene id: 1322246:BN4_RS00625
uniprot id: M1WN48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1322246:BN4 RS07925
gene id: 1322246:BN4_RS07925
uniprot id: M1WK16
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS03085
gene id: 1322246:BN4_RS03085
uniprot id: M1WQR6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1322246:BN4 RS15660
gene id: 1322246:BN4_RS15660
uniprot id: M1WNG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1322246:BN4 RS02680
gene id: 1322246:BN4_RS02680
uniprot id: M1WJE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1322246:BN4 RS00900
gene id: 1322246:BN4_RS00900
uniprot id: M1WL82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1322246:BN4 RS15285
gene id: 1322246:BN4_RS15285
uniprot id: M1WKV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS03850
gene id: 1322246:BN4_RS03850
uniprot id: M1WQZ5
names: Similarity
messages: Belongs to the FlgM family.

1322246:BN4 RS04660
gene id: 1322246:BN4_RS04660
uniprot id: M1WP89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1322246:BN4 RS08170
gene id: 1322246:BN4_RS08170
uniprot id: M1WM25
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1322246:BN4 RS11030
gene id: 1322246:BN4_RS11030
uniprot id: M1WKD9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1322246:BN4 RS06470
gene id: 1322246:BN4_RS06470
uniprot id: M1WVK0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1322246:BN4 RS16420
gene id: 1322246:BN4_RS16420
uniprot id: M1WSZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1322246:BN4 RS02475
gene id: 1322246:BN4_RS02475
uniprot id: M1WUP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1322246:BN4 RS01315
gene id: 1322246:BN4_RS01315
uniprot id: M1WUK4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1322246:BN4 RS02340
gene id: 1322246:BN4_RS02340
uniprot id: M1WQG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1322246:BN4 RS16520
gene id: 1322246:BN4_RS16520
uniprot id: M1WUB9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1322246:BN4 RS04590
gene id: 1322246:BN4_RS04590
uniprot id: M1WLM8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1322246:BN4 RS10005
gene id: 1322246:BN4_RS10005
uniprot id: M1WM97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1322246:BN4 RS16545
gene id: 1322246:BN4_RS16545
uniprot id: M1WL08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1322246:BN4 RS15470
gene id: 1322246:BN4_RS15470
uniprot id: M1WKW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS03615
gene id: 1322246:BN4_RS03615
uniprot id: M1WQX5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS09510
gene id: 1322246:BN4_RS09510
uniprot id: M1WK79
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS07390
gene id: 1322246:BN4_RS07390
uniprot id: M1WJY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1322246:BN4 RS04910
gene id: 1322246:BN4_RS04910
uniprot id: M1WV68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1322246:BN4 RS12320
gene id: 1322246:BN4_RS12320
uniprot id: M1WKJ1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1322246:BN4 RS15850
gene id: 1322246:BN4_RS15850
uniprot id: M1WYK2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1322246:BN4 RS01100
gene id: 1322246:BN4_RS01100
uniprot id: M1WNA7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS11465
gene id: 1322246:BN4_RS11465
uniprot id: M1WX52
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1322246:BN4 RS10795
gene id: 1322246:BN4_RS10795
uniprot id: M1WKC9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1322246:BN4 RS16220
gene id: 1322246:BN4_RS16220
uniprot id: M1WKZ5
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS02380
gene id: 1322246:BN4_RS02380
uniprot id: M1WUP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1322246:BN4 RS12845
gene id: 1322246:BN4_RS12845
uniprot id: M1WTP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1322246:BN4 RS11110
gene id: 1322246:BN4_RS11110
uniprot id: M1WTC7
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS07730
gene id: 1322246:BN4_RS07730
uniprot id: M1WQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS03685
gene id: 1322246:BN4_RS03685
uniprot id: M1WJI5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1322246:BN4 RS09330
gene id: 1322246:BN4_RS09330
uniprot id: M1WM71
names: Similarity
messages: Belongs to the HdrA family.

1322246:BN4 RS01450
gene id: 1322246:BN4_RS01450
uniprot id: M1WNE1
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS04005
gene id: 1322246:BN4_RS04005
uniprot id: M1WUZ2
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1322246:BN4 RS04455
gene id: 1322246:BN4_RS04455
uniprot id: M1WR49
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1322246:BN4 RS16725
gene id: 1322246:BN4_RS16725
uniprot id: M1WUC7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1322246:BN4 RS03125
gene id: 1322246:BN4_RS03125
uniprot id: M1WLG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS16575
gene id: 1322246:BN4_RS16575
uniprot id: M1WUC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1322246:BN4 RS00295
gene id: 1322246:BN4_RS00295
uniprot id: M1WJ52
names: Similarity
messages: Belongs to the RutC family.

1322246:BN4 RS06550
gene id: 1322246:BN4_RS06550
uniprot id: M1WJV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS16585
gene id: 1322246:BN4_RS16585
uniprot id: M1WT07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1322246:BN4 RS10085
gene id: 1322246:BN4_RS10085
uniprot id: M1WKA1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1322246:BN4 RS03565
gene id: 1322246:BN4_RS03565
uniprot id: M1WQX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS07865
gene id: 1322246:BN4_RS07865
uniprot id: M1WSB6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1322246:BN4 RS04030
gene id: 1322246:BN4_RS04030
uniprot id: M1WUZ3
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

1322246:BN4 RS03045
gene id: 1322246:BN4_RS03045
uniprot id: M1WUS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1322246:BN4 RS10035
gene id: 1322246:BN4_RS10035
uniprot id: M1WK99
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1322246:BN4 RS01600
gene id: 1322246:BN4_RS01600
uniprot id: M1WJA2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1322246:BN4 RS07070
gene id: 1322246:BN4_RS07070
uniprot id: M1WS03
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1322246:BN4 RS16495
gene id: 1322246:BN4_RS16495
uniprot id: M1WSZ8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1322246:BN4 RS16620
gene id: 1322246:BN4_RS16620
uniprot id: M1WL11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1322246:BN4 RS13765
gene id: 1322246:BN4_RS13765
uniprot id: M1WTX1
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1322246:BN4 RS01790
gene id: 1322246:BN4_RS01790
uniprot id: M1WNH4
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS11550
gene id: 1322246:BN4_RS11550
uniprot id: M1WRG7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1322246:BN4 RS08255
gene id: 1322246:BN4_RS08255
uniprot id: M1WK29
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1322246:BN4 RS14350
gene id: 1322246:BN4_RS14350
uniprot id: M1WSB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS08805
gene id: 1322246:BN4_RS08805
uniprot id: M1WQJ2
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1322246:BN4 RS00335
gene id: 1322246:BN4_RS00335
uniprot id: M1WL60
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1322246:BN4 RS11915
gene id: 1322246:BN4_RS11915
uniprot id: M1WMH4
names: Similarity
messages: Belongs to the asparaginase 1 family.

1322246:BN4 RS00670
gene id: 1322246:BN4_RS00670
uniprot id: M1WUH8
names: Subunit
messages: Homodimer.

1322246:BN4 RS04595
gene id: 1322246:BN4_RS04595
uniprot id: M1WJM1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS01175
gene id: 1322246:BN4_RS01175
uniprot id: M1WNB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1322246:BN4 RS01995
gene id: 1322246:BN4_RS01995
uniprot id: M1WUN0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1322246:BN4 RS11175
gene id: 1322246:BN4_RS11175
uniprot id: M1WRC7
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS07335
gene id: 1322246:BN4_RS07335
uniprot id: M1WLZ0
names: Similarity
messages: Belongs to the GSP E family.

1322246:BN4 RS03355
gene id: 1322246:BN4_RS03355
uniprot id: M1WJH2
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS06245
gene id: 1322246:BN4_RS06245
uniprot id: M1WLU8
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS00980
gene id: 1322246:BN4_RS00980
uniprot id: M1WL85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1322246:BN4 RS12220
gene id: 1322246:BN4_RS12220
uniprot id: M1WMI6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1322246:BN4 RS08065
gene id: 1322246:BN4_RS08065
uniprot id: M1WQ98
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1322246:BN4 RS14960
gene id: 1322246:BN4_RS14960
uniprot id: M1WY89
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1322246:BN4 RS02005
gene id: 1322246:BN4_RS02005
uniprot id: M1WLC5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1322246:BN4 RS16570
gene id: 1322246:BN4_RS16570
uniprot id: M1WL09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1322246:BN4 RS08725
gene id: 1322246:BN4_RS08725
uniprot id: M1WQI4
names: Similarity
messages: Belongs to the MlaA family.

1322246:BN4 RS10915
gene id: 1322246:BN4_RS10915
uniprot id: M1WKD4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1322246:BN4 RS16875
gene id: 1322246:BN4_RS16875
uniprot id: M1WL21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1322246:BN4 RS04235
gene id: 1322246:BN4_RS04235
uniprot id: M1WV06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1322246:BN4 RS16215
gene id: 1322246:BN4_RS16215
uniprot id: M1WNN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1322246:BN4 RS09550
gene id: 1322246:BN4_RS09550
uniprot id: M1WQS0
names: Similarity
messages: Belongs to the peptidase S24 family.

1322246:BN4 RS08400
gene id: 1322246:BN4_RS08400
uniprot id: M1WM34
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1322246:BN4 RS01555
gene id: 1322246:BN4_RS01555
uniprot id: M1WUL2
names: Similarity
messages: Belongs to the ros/MucR family.

1322246:BN4 RS08190
gene id: 1322246:BN4_RS08190
uniprot id: M1WQB8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1322246:BN4 RS00810
gene id: 1322246:BN4_RS00810
uniprot id: M1WQ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1322246:BN4 RS02940
gene id: 1322246:BN4_RS02940
uniprot id: M1WUR7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1322246:BN4 RS09970
gene id: 1322246:BN4_RS09970
uniprot id: M1WQW4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS01290
gene id: 1322246:BN4_RS01290
uniprot id: M1WUK3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1322246:BN4 RS15510
gene id: 1322246:BN4_RS15510
uniprot id: M1WYF5
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1322246:BN4 RS03500
gene id: 1322246:BN4_RS03500
uniprot id: M1WUW1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1322246:BN4 RS16485
gene id: 1322246:BN4_RS16485
uniprot id: M1WUB8
names: Similarity
messages: Belongs to the HypE family.

1322246:BN4 RS11385
gene id: 1322246:BN4_RS11385
uniprot id: M1WTE7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1322246:BN4 RS13900
gene id: 1322246:BN4_RS13900
uniprot id: M1WS67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1322246:BN4 RS03640
gene id: 1322246:BN4_RS03640
uniprot id: M1WQX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1322246:BN4 RS10345
gene id: 1322246:BN4_RS10345
uniprot id: M1WKB1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1322246:BN4 RS05420
gene id: 1322246:BN4_RS05420
uniprot id: M1WJQ6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1322246:BN4 RS03930
gene id: 1322246:BN4_RS03930
uniprot id: M1WUY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1322246:BN4 RS06525
gene id: 1322246:BN4_RS06525
uniprot id: M1WLV9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1322246:BN4 RS14535
gene id: 1322246:BN4_RS14535
uniprot id: M1WN21
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS02235
gene id: 1322246:BN4_RS02235
uniprot id: M1WQE8
names: Similarity
messages: Belongs to the leucine-binding protein family.

1322246:BN4 RS15230
gene id: 1322246:BN4_RS15230
uniprot id: M1WSL5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1322246:BN4 RS00820
gene id: 1322246:BN4_RS00820
uniprot id: M1WN81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1322246:BN4 RS07400
gene id: 1322246:BN4_RS07400
uniprot id: M1WVS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1322246:BN4 RS13695
gene id: 1322246:BN4_RS13695
uniprot id: M1WMT9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1322246:BN4 RS02975
gene id: 1322246:BN4_RS02975
uniprot id: M1WLG3
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS04410
gene id: 1322246:BN4_RS04410
uniprot id: M1WV16
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS03815
gene id: 1322246:BN4_RS03815
uniprot id: M1WLJ6
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1322246:BN4 RS09770
gene id: 1322246:BN4_RS09770
uniprot id: M1WWK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1322246:BN4 RS08310
gene id: 1322246:BN4_RS08310
uniprot id: M1WSI3
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS14755
gene id: 1322246:BN4_RS14755
uniprot id: M1WKT6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1322246:BN4 RS09245
gene id: 1322246:BN4_RS09245
uniprot id: M1WWD3
names: Similarity
messages: Belongs to the histone deacetylase family.

1322246:BN4 RS12300
gene id: 1322246:BN4_RS12300
uniprot id: M1WTL0
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS00905
gene id: 1322246:BN4_RS00905
uniprot id: M1WJ76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1322246:BN4 RS13865
gene id: 1322246:BN4_RS13865
uniprot id: M1WTX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1322246:BN4 RS09030
gene id: 1322246:BN4_RS09030
uniprot id: M1WM59
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS15560
gene id: 1322246:BN4_RS15560
uniprot id: M1WU80
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1322246:BN4 RS08195
gene id: 1322246:BN4_RS08195
uniprot id: M1WM26
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS02715
gene id: 1322246:BN4_RS02715
uniprot id: M1WNS9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1322246:BN4 RS12115
gene id: 1322246:BN4_RS12115
uniprot id: M1WXC0
names: Similarity
messages: Belongs to the Skp family.

1322246:BN4 RS07010
gene id: 1322246:BN4_RS07010
uniprot id: M1WLX7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1322246:BN4 RS03750
gene id: 1322246:BN4_RS03750
uniprot id: M1WP23
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1322246:BN4 RS10095
gene id: 1322246:BN4_RS10095
uniprot id: M1WWN9
names: Similarity
messages: Belongs to the MotB family.

1322246:BN4 RS02195
gene id: 1322246:BN4_RS02195
uniprot id: M1WNL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1322246:BN4 RS16325
gene id: 1322246:BN4_RS16325
uniprot id: M1WNP2
names: Similarity
messages: Belongs to the RecJ family.

1322246:BN4 RS05100
gene id: 1322246:BN4_RS05100
uniprot id: M1WV87
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1322246:BN4 RS15730
gene id: 1322246:BN4_RS15730
uniprot id: M1WSS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemerythrin family.
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1322246:BN4 RS07320
gene id: 1322246:BN4_RS07320
uniprot id: M1WS30
names: Similarity
messages: Belongs to the bacterial secretin family.

1322246:BN4 RS11985
gene id: 1322246:BN4_RS11985
uniprot id: M1WRL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1322246:BN4 RS09630
gene id: 1322246:BN4_RS09630
uniprot id: M1WM83
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1322246:BN4 RS02855
gene id: 1322246:BN4_RS02855
uniprot id: M1WQN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1322246:BN4 RS15105
gene id: 1322246:BN4_RS15105
uniprot id: M1WU50
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1322246:BN4 RS03945
gene id: 1322246:BN4_RS03945
uniprot id: M1WJJ5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1322246:BN4 RS06555
gene id: 1322246:BN4_RS06555
uniprot id: M1WRV8
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS02695
gene id: 1322246:BN4_RS02695
uniprot id: M1WNS7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1322246:BN4 RS03130
gene id: 1322246:BN4_RS03130
uniprot id: M1WJG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS13610
gene id: 1322246:BN4_RS13610
uniprot id: M1WS39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS04165
gene id: 1322246:BN4_RS04165
uniprot id: M1WJK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1322246:BN4 RS09960
gene id: 1322246:BN4_RS09960
uniprot id: M1WWM5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1322246:BN4 RS04315
gene id: 1322246:BN4_RS04315
uniprot id: M1WP62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1322246:BN4 RS07025
gene id: 1322246:BN4_RS07025
uniprot id: M1WVN6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1322246:BN4 RS08385
gene id: 1322246:BN4_RS08385
uniprot id: M1WSJ0
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1322246:BN4 RS04255
gene id: 1322246:BN4_RS04255
uniprot id: M1WR30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1322246:BN4 RS06095
gene id: 1322246:BN4_RS06095
uniprot id: M1WRR3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1322246:BN4 RS01165
gene id: 1322246:BN4_RS01165
uniprot id: M1WQ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

1322246:BN4 RS16090
gene id: 1322246:BN4_RS16090
uniprot id: M1WSX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

1322246:BN4 RS01065
gene id: 1322246:BN4_RS01065
uniprot id: M1WQ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1322246:BN4 RS09210
gene id: 1322246:BN4_RS09210
uniprot id: M1WK67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS09470
gene id: 1322246:BN4_RS09470
uniprot id: M1WWG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1322246:BN4 RS01585
gene id: 1322246:BN4_RS01585
uniprot id: M1WUL3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1322246:BN4 RS17090
gene id: 1322246:BN4_RS17090
uniprot id: M1WVJ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1322246:BN4 RS01685
gene id: 1322246:BN4_RS01685
uniprot id: M1WUL7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1322246:BN4 RS08455
gene id: 1322246:BN4_RS08455
uniprot id: M1WK37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1322246:BN4 RS11115
gene id: 1322246:BN4_RS11115
uniprot id: M1WX15
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1322246:BN4 RS02310
gene id: 1322246:BN4_RS02310
uniprot id: M1WJD0
names: Similarity
messages: Belongs to the GcvT family.

1322246:BN4 RS02850
gene id: 1322246:BN4_RS02850
uniprot id: M1WJF2
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1322246:BN4 RS14460
gene id: 1322246:BN4_RS14460
uniprot id: M1WN13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1322246:BN4 RS14585
gene id: 1322246:BN4_RS14585
uniprot id: M1WU20
names: Similarity
messages: Belongs to the P(II) protein family.

1322246:BN4 RS16335
gene id: 1322246:BN4_RS16335
uniprot id: M1WUB2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1322246:BN4 RS10110
gene id: 1322246:BN4_RS10110
uniprot id: M1WKA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1322246:BN4 RS15930
gene id: 1322246:BN4_RS15930
uniprot id: M1WSV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1322246:BN4 RS14990
gene id: 1322246:BN4_RS14990
uniprot id: M1WSI2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1322246:BN4 RS16635
gene id: 1322246:BN4_RS16635
uniprot id: M1WT13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1322246:BN4 RS08645
gene id: 1322246:BN4_RS08645
uniprot id: M1WW63
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1322246:BN4 RS06520
gene id: 1322246:BN4_RS06520
uniprot id: M1WPR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1322246:BN4 RS02515
gene id: 1322246:BN4_RS02515
uniprot id: M1WJD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1322246:BN4 RS06770
gene id: 1322246:BN4_RS06770
uniprot id: M1WJW4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1322246:BN4 RS03755
gene id: 1322246:BN4_RS03755
uniprot id: M1WLJ4
names: Similarity
messages: Belongs to the DprA/Smf family.

1322246:BN4 RS04320
gene id: 1322246:BN4_RS04320
uniprot id: M1WLL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1322246:BN4 RS01400
gene id: 1322246:BN4_RS01400
uniprot id: M1WLA2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1322246:BN4 RS15355
gene id: 1322246:BN4_RS15355
uniprot id: M1WND0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1322246:BN4 RS02250
gene id: 1322246:BN4_RS02250
uniprot id: M1WNM0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

1322246:BN4 RS01935
gene id: 1322246:BN4_RS01935
uniprot id: M1WJB6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1322246:BN4 RS02230
gene id: 1322246:BN4_RS02230
uniprot id: M1WJC7
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS14200
gene id: 1322246:BN4_RS14200
uniprot id: M1WSA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS03520
gene id: 1322246:BN4_RS03520
uniprot id: M1WQW7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS15465
gene id: 1322246:BN4_RS15465
uniprot id: M1WNE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS02725
gene id: 1322246:BN4_RS02725
uniprot id: M1WJE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS00350
gene id: 1322246:BN4_RS00350
uniprot id: M1WUG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS16055
gene id: 1322246:BN4_RS16055
uniprot id: M1WUA0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1322246:BN4 RS15500
gene id: 1322246:BN4_RS15500
uniprot id: M1WKW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1322246:BN4 RS12995
gene id: 1322246:BN4_RS12995
uniprot id: M1WTR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS16230
gene id: 1322246:BN4_RS16230
uniprot id: M1WYN4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1322246:BN4 RS12870
gene id: 1322246:BN4_RS12870
uniprot id: M1WTP6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1322246:BN4 RS08350
gene id: 1322246:BN4_RS08350
uniprot id: M1WQE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

1322246:BN4 RS00355
gene id: 1322246:BN4_RS00355
uniprot id: M1WN10
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1322246:BN4 RS07750
gene id: 1322246:BN4_RS07750
uniprot id: M1WVW8
names: Similarity
messages: Belongs to the aldose epimerase family.

1322246:BN4 RS16270
gene id: 1322246:BN4_RS16270
uniprot id: M1WSY2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1322246:BN4 RS03490
gene id: 1322246:BN4_RS03490
uniprot id: M1WJH7
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1322246:BN4 RS04560
gene id: 1322246:BN4_RS04560
uniprot id: M1WP81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1322246:BN4 RS10145
gene id: 1322246:BN4_RS10145
uniprot id: M1WWP7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1322246:BN4 RS06185
gene id: 1322246:BN4_RS06185
uniprot id: M1WVI1
names: Similarity
messages: Belongs to the thioesterase family.

1322246:BN4 RS12330
gene id: 1322246:BN4_RS12330
uniprot id: M1WXE6
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1322246:BN4 RS10905
gene id: 1322246:BN4_RS10905
uniprot id: M1WR99
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1322246:BN4 RS14795
gene id: 1322246:BN4_RS14795
uniprot id: M1WSG2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1322246:BN4 RS08595
gene id: 1322246:BN4_RS08595
uniprot id: M1WQH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1322246:BN4 RS05875
gene id: 1322246:BN4_RS05875
uniprot id: M1WPK1
names: Subunit
messages: Heterodimer of a large and a small subunit.

1322246:BN4 RS00560
gene id: 1322246:BN4_RS00560
uniprot id: M1WN41
names: Similarity
messages: Belongs to the Nth/MutY family.

1322246:BN4 RS14135
gene id: 1322246:BN4_RS14135
uniprot id: M1WMX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1322246:BN4 RS14835
gene id: 1322246:BN4_RS14835
uniprot id: M1WY74
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS13920
gene id: 1322246:BN4_RS13920
uniprot id: M1WXY2
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1322246:BN4 RS04790
gene id: 1322246:BN4_RS04790
uniprot id: M1WJM9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1322246:BN4 RS03495
gene id: 1322246:BN4_RS03495
uniprot id: M1WQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS17045
gene id: 1322246:BN4_RS17045
uniprot id: M1WPE5
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS07135
gene id: 1322246:BN4_RS07135
uniprot id: M1WLY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1322246:BN4 RS09010
gene id: 1322246:BN4_RS09010
uniprot id: M1WK59
names: Similarity
messages: Belongs to the universal stress protein A family.

1322246:BN4 RS04945
gene id: 1322246:BN4_RS04945
uniprot id: M1WLP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1322246:BN4 RS13585
gene id: 1322246:BN4_RS13585
uniprot id: M1WS35
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1322246:BN4 RS04010
gene id: 1322246:BN4_RS04010
uniprot id: M1WP41
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1322246:BN4 RS12130
gene id: 1322246:BN4_RS12130
uniprot id: M1WKI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS02050
gene id: 1322246:BN4_RS02050
uniprot id: M1WUN2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1322246:BN4 RS10665
gene id: 1322246:BN4_RS10665
uniprot id: M1WR59
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1322246:BN4 RS07445
gene id: 1322246:BN4_RS07445
uniprot id: M1WS50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1322246:BN4 RS13345
gene id: 1322246:BN4_RS13345
uniprot id: M1WKN1
names: Similarity
messages: Belongs to the peptidase C40 family.

1322246:BN4 RS13365
gene id: 1322246:BN4_RS13365
uniprot id: M1WMQ9
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS09120
gene id: 1322246:BN4_RS09120
uniprot id: M1WQM5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1322246:BN4 RS16680
gene id: 1322246:BN4_RS16680
uniprot id: M1WYS5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1322246:BN4 RS12290
gene id: 1322246:BN4_RS12290
uniprot id: M1WMI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1322246:BN4 RS07560
gene id: 1322246:BN4_RS07560
uniprot id: M1WLZ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS16195
gene id: 1322246:BN4_RS16195
uniprot id: M1WKZ4
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1322246:BN4 RS16265
gene id: 1322246:BN4_RS16265
uniprot id: M1WYN9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1322246:BN4 RS09505
gene id: 1322246:BN4_RS09505
uniprot id: M1WM78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1322246:BN4 RS08450
gene id: 1322246:BN4_RS08450
uniprot id: M1WM36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1322246:BN4 RS08425
gene id: 1322246:BN4_RS08425
uniprot id: M1WM35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1322246:BN4 RS16160
gene id: 1322246:BN4_RS16160
uniprot id: M1WSX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1322246:BN4 RS12675
gene id: 1322246:BN4_RS12675
uniprot id: M1WKK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1322246:BN4 RS02165
gene id: 1322246:BN4_RS02165
uniprot id: M1WUN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1322246:BN4 RS02260
gene id: 1322246:BN4_RS02260
uniprot id: M1WJC8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1322246:BN4 RS12640
gene id: 1322246:BN4_RS12640
uniprot id: M1WRT3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1322246:BN4 RS13965
gene id: 1322246:BN4_RS13965
uniprot id: M1WTY6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1322246:BN4 RS01005
gene id: 1322246:BN4_RS01005
uniprot id: M1WL86
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1322246:BN4 RS03135
gene id: 1322246:BN4_RS03135
uniprot id: M1WQS2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1322246:BN4 RS02455
gene id: 1322246:BN4_RS02455
uniprot id: M1WUP7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1322246:BN4 RS08730
gene id: 1322246:BN4_RS08730
uniprot id: M1WM47
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1322246:BN4 RS06605
gene id: 1322246:BN4_RS06605
uniprot id: M1WRW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1322246:BN4 RS02325
gene id: 1322246:BN4_RS02325
uniprot id: M1WNN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1322246:BN4 RS12250
gene id: 1322246:BN4_RS12250
uniprot id: M1WKI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1322246:BN4 RS02040
gene id: 1322246:BN4_RS02040
uniprot id: M1WJC0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1322246:BN4 RS10365
gene id: 1322246:BN4_RS10365
uniprot id: M1WKB2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1322246:BN4 RS00975
gene id: 1322246:BN4_RS00975
uniprot id: M1WN96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1322246:BN4 RS14995
gene id: 1322246:BN4_RS14995
uniprot id: M1WN77
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1322246:BN4 RS08815
gene id: 1322246:BN4_RS08815
uniprot id: M1WK51
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1322246:BN4 RS08005
gene id: 1322246:BN4_RS08005
uniprot id: M1WK19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1322246:BN4 RS02270
gene id: 1322246:BN4_RS02270
uniprot id: M1WUP0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1322246:BN4 RS01940
gene id: 1322246:BN4_RS01940
uniprot id: M1WQB7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1322246:BN4 RS03675
gene id: 1322246:BN4_RS03675
uniprot id: M1WP17
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1322246:BN4 RS02010
gene id: 1322246:BN4_RS02010
uniprot id: M1WJB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

1322246:BN4 RS16540
gene id: 1322246:BN4_RS16540
uniprot id: M1WNR1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1322246:BN4 RS11960
gene id: 1322246:BN4_RS11960
uniprot id: M1WRK9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS14105
gene id: 1322246:BN4_RS14105
uniprot id: M1WS88
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1322246:BN4 RS10070
gene id: 1322246:BN4_RS10070
uniprot id: M1WWN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1322246:BN4 RS16175
gene id: 1322246:BN4_RS16175
uniprot id: M1WUA5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1322246:BN4 RS16140
gene id: 1322246:BN4_RS16140
uniprot id: M1WNM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1322246:BN4 RS13615
gene id: 1322246:BN4_RS13615
uniprot id: M1WMT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS16530
gene id: 1322246:BN4_RS16530
uniprot id: M1WYR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1322246:BN4 RS12230
gene id: 1322246:BN4_RS12230
uniprot id: M1WTK6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1322246:BN4 RS00305
gene id: 1322246:BN4_RS00305
uniprot id: M1WUG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1322246:BN4 RS00095
gene id: 1322246:BN4_RS00095
uniprot id: M1WMX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1322246:BN4 RS09065
gene id: 1322246:BN4_RS09065
uniprot id: M1WSR0
names: Similarity
messages: Belongs to the HdrA family.

1322246:BN4 RS04420
gene id: 1322246:BN4_RS04420
uniprot id: M1WLM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1322246:BN4 RS07905
gene id: 1322246:BN4_RS07905
uniprot id: M1WSC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1322246:BN4 RS07470
gene id: 1322246:BN4_RS07470
uniprot id: M1WJZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1322246:BN4 RS08050
gene id: 1322246:BN4_RS08050
uniprot id: M1WK21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1322246:BN4 RS05950
gene id: 1322246:BN4_RS05950
uniprot id: M1WLT5
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1322246:BN4 RS02655
gene id: 1322246:BN4_RS02655
uniprot id: M1WJE4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1322246:BN4 RS05900
gene id: 1322246:BN4_RS05900
uniprot id: M1WLT3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1322246:BN4 RS02760
gene id: 1322246:BN4_RS02760
uniprot id: M1WUR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

1322246:BN4 RS11040
gene id: 1322246:BN4_RS11040
uniprot id: M1WX08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1322246:BN4 RS03915
gene id: 1322246:BN4_RS03915
uniprot id: M1WLK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1322246:BN4 RS11430
gene id: 1322246:BN4_RS11430
uniprot id: M1WKF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1322246:BN4 RS12450
gene id: 1322246:BN4_RS12450
uniprot id: M1WKJ6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1322246:BN4 RS02215
gene id: 1322246:BN4_RS02215
uniprot id: M1WUN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1322246:BN4 RS07735
gene id: 1322246:BN4_RS07735
uniprot id: M1WM07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS13955
gene id: 1322246:BN4_RS13955
uniprot id: M1WMW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1322246:BN4 RS03705
gene id: 1322246:BN4_RS03705
uniprot id: M1WLJ2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1322246:BN4 RS11095
gene id: 1322246:BN4_RS11095
uniprot id: M1WRB9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS09150
gene id: 1322246:BN4_RS09150
uniprot id: M1WM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1322246:BN4 RS03905
gene id: 1322246:BN4_RS03905
uniprot id: M1WP34
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1322246:BN4 RS17175
gene id: 1322246:BN4_RS17175
uniprot id: M1WM42
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1322246:BN4 RS01955
gene id: 1322246:BN4_RS01955
uniprot id: M1WLC3
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS03715
gene id: 1322246:BN4_RS03715
uniprot id: M1WQY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

1322246:BN4 RS10045
gene id: 1322246:BN4_RS10045
uniprot id: M1WWN3
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS07345
gene id: 1322246:BN4_RS07345
uniprot id: M1WS32
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS00215
gene id: 1322246:BN4_RS00215
uniprot id: M1WMY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS08290
gene id: 1322246:BN4_RS08290
uniprot id: M1WW34
names: Similarity
messages: Belongs to the UPF0178 family.

1322246:BN4 RS04345
gene id: 1322246:BN4_RS04345
uniprot id: M1WLL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS07510
gene id: 1322246:BN4_RS07510
uniprot id: M1WJZ3
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

1322246:BN4 RS13025
gene id: 1322246:BN4_RS13025
uniprot id: M1WXP5
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS11615
gene id: 1322246:BN4_RS11615
uniprot id: M1WRH3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1322246:BN4 RS06410
gene id: 1322246:BN4_RS06410
uniprot id: M1WJU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTX toxin acyltransferase family.
messages: Cytoplasm
messages: Involved in fatty acylation of protoxin at internal lysine residues, thereby converting it to the active toxin.

1322246:BN4 RS06965
gene id: 1322246:BN4_RS06965
uniprot id: M1WRZ3
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS05810
gene id: 1322246:BN4_RS05810
uniprot id: M1WVF6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1322246:BN4 RS08525
gene id: 1322246:BN4_RS08525
uniprot id: M1WM39
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1322246:BN4 RS04130
gene id: 1322246:BN4_RS04130
uniprot id: M1WP49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1322246:BN4 RS05515
gene id: 1322246:BN4_RS05515
uniprot id: M1WVC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1322246:BN4 RS13810
gene id: 1322246:BN4_RS13810
uniprot id: M1WKP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1322246:BN4 RS02045
gene id: 1322246:BN4_RS02045
uniprot id: M1WQC8
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

1322246:BN4 RS03525
gene id: 1322246:BN4_RS03525
uniprot id: M1WUW3
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1322246:BN4 RS02585
gene id: 1322246:BN4_RS02585
uniprot id: M1WJE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1322246:BN4 RS01055
gene id: 1322246:BN4_RS01055
uniprot id: M1WL88
names: Similarity
messages: Belongs to the Skp family.

1322246:BN4 RS12655
gene id: 1322246:BN4_RS12655
uniprot id: M1WTM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1322246:BN4 RS16550
gene id: 1322246:BN4_RS16550
uniprot id: M1WUC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1322246:BN4 RS11690
gene id: 1322246:BN4_RS11690
uniprot id: M1WX74
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

1322246:BN4 RS09775
gene id: 1322246:BN4_RS09775
uniprot id: M1WQU3
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS01070
gene id: 1322246:BN4_RS01070
uniprot id: M1WUJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1322246:BN4 RS00925
gene id: 1322246:BN4_RS00925
uniprot id: M1WL83
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1322246:BN4 RS06455
gene id: 1322246:BN4_RS06455
uniprot id: M1WLV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS14620
gene id: 1322246:BN4_RS14620
uniprot id: M1WY56
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

1322246:BN4 RS08555
gene id: 1322246:BN4_RS08555
uniprot id: M1WK41
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1322246:BN4 RS08205
gene id: 1322246:BN4_RS08205
uniprot id: M1WK27
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS02055
gene id: 1322246:BN4_RS02055
uniprot id: M1WNJ7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1322246:BN4 RS12000
gene id: 1322246:BN4_RS12000
uniprot id: M1WTJ0
names: Subcellular Location Annotation
messages: Virion

1322246:BN4 RS12860
gene id: 1322246:BN4_RS12860
uniprot id: M1WMM1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1322246:BN4 RS01725
gene id: 1322246:BN4_RS01725
uniprot id: M1WJA7
names: Similarity
messages: Belongs to the UPF0166 family.

1322246:BN4 RS01750
gene id: 1322246:BN4_RS01750
uniprot id: M1WJA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1322246:BN4 RS07855
gene id: 1322246:BN4_RS07855
uniprot id: M1WM12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1322246:BN4 RS15080
gene id: 1322246:BN4_RS15080
uniprot id: M1WU48
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS01240
gene id: 1322246:BN4_RS01240
uniprot id: M1WUK1
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1322246:BN4 RS13660
gene id: 1322246:BN4_RS13660
uniprot id: M1WS44
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS08530
gene id: 1322246:BN4_RS08530
uniprot id: M1WK40
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1322246:BN4 RS12560
gene id: 1322246:BN4_RS12560
uniprot id: M1WXH5
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS15820
gene id: 1322246:BN4_RS15820
uniprot id: M1WU90
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1322246:BN4 RS07460
gene id: 1322246:BN4_RS07460
uniprot id: M1WQ13
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1322246:BN4 RS03605
gene id: 1322246:BN4_RS03605
uniprot id: M1WLI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1322246:BN4 RS04025
gene id: 1322246:BN4_RS04025
uniprot id: M1WR11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1322246:BN4 RS12695
gene id: 1322246:BN4_RS12695
uniprot id: M1WML0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1322246:BN4 RS16625
gene id: 1322246:BN4_RS16625
uniprot id: M1WUC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1322246:BN4 RS04740
gene id: 1322246:BN4_RS04740
uniprot id: M1WJM7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1322246:BN4 RS12455
gene id: 1322246:BN4_RS12455
uniprot id: M1WTL6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1322246:BN4 RS15675
gene id: 1322246:BN4_RS15675
uniprot id: M1WYH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1322246:BN4 RS16835
gene id: 1322246:BN4_RS16835
uniprot id: M1WYT8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1322246:BN4 RS14360
gene id: 1322246:BN4_RS14360
uniprot id: M1WKS0
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1322246:BN4 RS10685
gene id: 1322246:BN4_RS10685
uniprot id: M1WR62
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1322246:BN4 RS16445
gene id: 1322246:BN4_RS16445
uniprot id: M1WSZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1322246:BN4 RS00620
gene id: 1322246:BN4_RS00620
uniprot id: M1WUH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1322246:BN4 RS04770
gene id: 1322246:BN4_RS04770
uniprot id: M1WR84
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1322246:BN4 RS03270
gene id: 1322246:BN4_RS03270
uniprot id: M1WJG9
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS01780
gene id: 1322246:BN4_RS01780
uniprot id: M1WQ96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1322246:BN4 RS09485
gene id: 1322246:BN4_RS09485
uniprot id: M1WK78
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1322246:BN4 RS09600
gene id: 1322246:BN4_RS09600
uniprot id: M1WQS6
names: Similarity
messages: Belongs to the peptidase C56 family.

1322246:BN4 RS09595
gene id: 1322246:BN4_RS09595
uniprot id: M1WWI1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1322246:BN4 RS03725
gene id: 1322246:BN4_RS03725
uniprot id: M1WP21
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1322246:BN4 RS14920
gene id: 1322246:BN4_RS14920
uniprot id: M1WN68
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS03950
gene id: 1322246:BN4_RS03950
uniprot id: M1WR04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1322246:BN4 RS03805
gene id: 1322246:BN4_RS03805
uniprot id: M1WUX9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1322246:BN4 RS12840
gene id: 1322246:BN4_RS12840
uniprot id: M1WKL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1322246:BN4 RS04175
gene id: 1322246:BN4_RS04175
uniprot id: M1WV03
names: Similarity
messages: Belongs to the ComB family.

1322246:BN4 RS13605
gene id: 1322246:BN4_RS13605
uniprot id: M1WXV2
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS16295
gene id: 1322246:BN4_RS16295
uniprot id: M1WSY4
names: Similarity
messages: Belongs to the YicC/YloC family.

1322246:BN4 RS03810
gene id: 1322246:BN4_RS03810
uniprot id: M1WP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1322246:BN4 RS04295
gene id: 1322246:BN4_RS04295
uniprot id: M1WLL6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1322246:BN4 RS03040
gene id: 1322246:BN4_RS03040
uniprot id: M1WQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1322246:BN4 RS05855
gene id: 1322246:BN4_RS05855
uniprot id: M1WLT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS11505
gene id: 1322246:BN4_RS11505
uniprot id: M1WMF7
names: Similarity
messages: Belongs to the IMPACT family.

1322246:BN4 RS01875
gene id: 1322246:BN4_RS01875
uniprot id: M1WQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1322246:BN4 RS01405
gene id: 1322246:BN4_RS01405
uniprot id: M1WJ96
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1322246:BN4 RS13880
gene id: 1322246:BN4_RS13880
uniprot id: M1WMV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1322246:BN4 RS01040
gene id: 1322246:BN4_RS01040
uniprot id: M1WQ34
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS05935
gene id: 1322246:BN4_RS05935
uniprot id: M1WRP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1322246:BN4 RS10900
gene id: 1322246:BN4_RS10900
uniprot id: M1WWZ3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1322246:BN4 RS00945
gene id: 1322246:BN4_RS00945
uniprot id: M1WUI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1322246:BN4 RS09370
gene id: 1322246:BN4_RS09370
uniprot id: M1WWE7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

1322246:BN4 RS08060
gene id: 1322246:BN4_RS08060
uniprot id: M1WW03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS07205
gene id: 1322246:BN4_RS07205
uniprot id: M1WLY5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1322246:BN4 RS00220
gene id: 1322246:BN4_RS00220
uniprot id: M1WL55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS15700
gene id: 1322246:BN4_RS15700
uniprot id: M1WYH6
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS11010
gene id: 1322246:BN4_RS11010
uniprot id: M1WKD8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1322246:BN4 RS09930
gene id: 1322246:BN4_RS09930
uniprot id: M1WT03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS05050
gene id: 1322246:BN4_RS05050
uniprot id: M1WRC6
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1322246:BN4 RS01025
gene id: 1322246:BN4_RS01025
uniprot id: M1WNA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1322246:BN4 RS10430
gene id: 1322246:BN4_RS10430
uniprot id: M1WMB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

1322246:BN4 RS16065
gene id: 1322246:BN4_RS16065
uniprot id: M1WSW8
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS14675
gene id: 1322246:BN4_RS14675
uniprot id: M1WN40
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1322246:BN4 RS12745
gene id: 1322246:BN4_RS12745
uniprot id: M1WXK5
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1322246:BN4 RS15965
gene id: 1322246:BN4_RS15965
uniprot id: M1WKY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1322246:BN4 RS12395
gene id: 1322246:BN4_RS12395
uniprot id: M1WMJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1322246:BN4 RS02275
gene id: 1322246:BN4_RS02275
uniprot id: M1WNM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1322246:BN4 RS00180
gene id: 1322246:BN4_RS00180
uniprot id: M1WJ47
names: Similarity
messages: Belongs to the class-I fumarase family.

1322246:BN4 RS04035
gene id: 1322246:BN4_RS04035
uniprot id: M1WP42
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1322246:BN4 RS04310
gene id: 1322246:BN4_RS04310
uniprot id: M1WV11
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1322246:BN4 RS15530
gene id: 1322246:BN4_RS15530
uniprot id: M1WKW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

1322246:BN4 RS05970
gene id: 1322246:BN4_RS05970
uniprot id: M1WPL1
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

1322246:BN4 RS14925
gene id: 1322246:BN4_RS14925
uniprot id: M1WKU4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1322246:BN4 RS02395
gene id: 1322246:BN4_RS02395
uniprot id: M1WJD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1322246:BN4 RS03575
gene id: 1322246:BN4_RS03575
uniprot id: M1WP10
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1322246:BN4 RS11205
gene id: 1322246:BN4_RS11205
uniprot id: M1WX21
names: Similarity
messages: Belongs to the barstar family.

1322246:BN4 RS04435
gene id: 1322246:BN4_RS04435
uniprot id: M1WV17
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1322246:BN4 RS06875
gene id: 1322246:BN4_RS06875
uniprot id: M1WJW8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1322246:BN4 RS14850
gene id: 1322246:BN4_RS14850
uniprot id: M1WN61
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS00425
gene id: 1322246:BN4_RS00425
uniprot id: M1WUG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1322246:BN4 RS15090
gene id: 1322246:BN4_RS15090
uniprot id: M1WSJ5
names: Similarity
messages: Belongs to the peptidase S16 family.

1322246:BN4 RS03170
gene id: 1322246:BN4_RS03170
uniprot id: M1WNX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1322246:BN4 RS14075
gene id: 1322246:BN4_RS14075
uniprot id: M1WS85
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1322246:BN4 RS09710
gene id: 1322246:BN4_RS09710
uniprot id: M1WK87
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1322246:BN4 RS13715
gene id: 1322246:BN4_RS13715
uniprot id: M1WXW1
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS04880
gene id: 1322246:BN4_RS04880
uniprot id: M1WRA1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1322246:BN4 RS12620
gene id: 1322246:BN4_RS12620
uniprot id: M1WMK4
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1322246:BN4 RS07225
gene id: 1322246:BN4_RS07225
uniprot id: M1WPY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1322246:BN4 RS04510
gene id: 1322246:BN4_RS04510
uniprot id: M1WLM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1322246:BN4 RS15145
gene id: 1322246:BN4_RS15145
uniprot id: M1WN98
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1322246:BN4 RS15290
gene id: 1322246:BN4_RS15290
uniprot id: M1WU64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS09480
gene id: 1322246:BN4_RS09480
uniprot id: M1WM77
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS11350
gene id: 1322246:BN4_RS11350
uniprot id: M1WMF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1322246:BN4 RS10240
gene id: 1322246:BN4_RS10240
uniprot id: M1WT47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

1322246:BN4 RS11375
gene id: 1322246:BN4_RS11375
uniprot id: M1WMF2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1322246:BN4 RS11295
gene id: 1322246:BN4_RS11295
uniprot id: M1WTE0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1322246:BN4 RS01000
gene id: 1322246:BN4_RS01000
uniprot id: M1WN97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1322246:BN4 RS00630
gene id: 1322246:BN4_RS00630
uniprot id: M1WL71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS08160
gene id: 1322246:BN4_RS08160
uniprot id: M1WW16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1322246:BN4 RS14005
gene id: 1322246:BN4_RS14005
uniprot id: M1WMW6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1322246:BN4 RS01420
gene id: 1322246:BN4_RS01420
uniprot id: M1WND9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1322246:BN4 RS12785
gene id: 1322246:BN4_RS12785
uniprot id: M1WML5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1322246:BN4 RS12865
gene id: 1322246:BN4_RS12865
uniprot id: M1WKL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS16710
gene id: 1322246:BN4_RS16710
uniprot id: M1WT21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1322246:BN4 RS10885
gene id: 1322246:BN4_RS10885
uniprot id: M1WMD2
names: Similarity
messages: Belongs to the fabD family.

1322246:BN4 RS14485
gene id: 1322246:BN4_RS14485
uniprot id: M1WN16
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS11980
gene id: 1322246:BN4_RS11980
uniprot id: M1WXA4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1322246:BN4 RS01805
gene id: 1322246:BN4_RS01805
uniprot id: M1WQA0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1322246:BN4 RS02400
gene id: 1322246:BN4_RS02400
uniprot id: M1WQG9
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS04440
gene id: 1322246:BN4_RS04440
uniprot id: M1WP72
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1322246:BN4 RS11270
gene id: 1322246:BN4_RS11270
uniprot id: M1WKE8
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1322246:BN4 RS15400
gene id: 1322246:BN4_RS15400
uniprot id: M1WSN8
names: Similarity
messages: Belongs to the LarC family.

1322246:BN4 RS01105
gene id: 1322246:BN4_RS01105
uniprot id: M1WL90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1322246:BN4 RS02800
gene id: 1322246:BN4_RS02800
uniprot id: M1WJF0
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS13235
gene id: 1322246:BN4_RS13235
uniprot id: M1WS04
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1322246:BN4 RS00610
gene id: 1322246:BN4_RS00610
uniprot id: M1WJ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1322246:BN4 RS16085
gene id: 1322246:BN4_RS16085
uniprot id: M1WYM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

1322246:BN4 RS09455
gene id: 1322246:BN4_RS09455
uniprot id: M1WM76
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

1322246:BN4 RS12595
gene id: 1322246:BN4_RS12595
uniprot id: M1WMK2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1322246:BN4 RS08765
gene id: 1322246:BN4_RS08765
uniprot id: M1WSM9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1322246:BN4 RS14065
gene id: 1322246:BN4_RS14065
uniprot id: M1WTZ3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1322246:BN4 RS17035
gene id: 1322246:BN4_RS17035
uniprot id: M1WPD2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1322246:BN4 RS08360
gene id: 1322246:BN4_RS08360
uniprot id: M1WK33
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1322246:BN4 RS01775
gene id: 1322246:BN4_RS01775
uniprot id: M1WJA9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1322246:BN4 RS05165
gene id: 1322246:BN4_RS05165
uniprot id: M1WRE2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1322246:BN4 RS16655
gene id: 1322246:BN4_RS16655
uniprot id: M1WYS3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1322246:BN4 RS11145
gene id: 1322246:BN4_RS11145
uniprot id: M1WRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS08080
gene id: 1322246:BN4_RS08080
uniprot id: M1WSE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1322246:BN4 RS03050
gene id: 1322246:BN4_RS03050
uniprot id: M1WNW4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1322246:BN4 RS13845
gene id: 1322246:BN4_RS13845
uniprot id: M1WXX3
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS03630
gene id: 1322246:BN4_RS03630
uniprot id: M1WLI9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1322246:BN4 RS13505
gene id: 1322246:BN4_RS13505
uniprot id: M1WXU2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1322246:BN4 RS10710
gene id: 1322246:BN4_RS10710
uniprot id: M1WMC5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1322246:BN4 RS09870
gene id: 1322246:BN4_RS09870
uniprot id: M1WK93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

1322246:BN4 RS02220
gene id: 1322246:BN4_RS02220
uniprot id: M1WNL7
names: Similarity
messages: Belongs to the MotB family.

1322246:BN4 RS09935
gene id: 1322246:BN4_RS09935
uniprot id: M1WWM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1322246:BN4 RS09640
gene id: 1322246:BN4_RS09640
uniprot id: M1WSX1
names: Similarity
messages: Belongs to the GPI family.

1322246:BN4 RS01740
gene id: 1322246:BN4_RS01740
uniprot id: M1WNG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1322246:BN4 RS02335
gene id: 1322246:BN4_RS02335
uniprot id: M1WJD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1322246:BN4 RS11770
gene id: 1322246:BN4_RS11770
uniprot id: M1WRI8
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1322246:BN4 RS01680
gene id: 1322246:BN4_RS01680
uniprot id: M1WQ85
names: Similarity
messages: Belongs to the thioredoxin family.

1322246:BN4 RS09425
gene id: 1322246:BN4_RS09425
uniprot id: M1WQQ7
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1322246:BN4 RS00915
gene id: 1322246:BN4_RS00915
uniprot id: M1WUI8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1322246:BN4 RS00525
gene id: 1322246:BN4_RS00525
uniprot id: M1WUH3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1322246:BN4 RS15705
gene id: 1322246:BN4_RS15705
uniprot id: M1WSS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

1322246:BN4 RS03060
gene id: 1322246:BN4_RS03060
uniprot id: M1WJG0
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1322246:BN4 RS08915
gene id: 1322246:BN4_RS08915
uniprot id: M1WSP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1322246:BN4 RS09525
gene id: 1322246:BN4_RS09525
uniprot id: M1WQR7
names: Similarity
messages: Belongs to the SCO1/2 family.

1322246:BN4 RS08020
gene id: 1322246:BN4_RS08020
uniprot id: M1WQ90
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS05535
gene id: 1322246:BN4_RS05535
uniprot id: M1WVC8
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1322246:BN4 RS03730
gene id: 1322246:BN4_RS03730
uniprot id: M1WLJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1322246:BN4 RS00245
gene id: 1322246:BN4_RS00245
uniprot id: M1WL56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1322246:BN4 RS12925
gene id: 1322246:BN4_RS12925
uniprot id: M1WKL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS02300
gene id: 1322246:BN4_RS02300
uniprot id: M1WNM8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1322246:BN4 RS01280
gene id: 1322246:BN4_RS01280
uniprot id: M1WJ91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1322246:BN4 RS16650
gene id: 1322246:BN4_RS16650
uniprot id: M1WUC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1322246:BN4 RS03900
gene id: 1322246:BN4_RS03900
uniprot id: M1WUY5
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1322246:BN4 RS02035
gene id: 1322246:BN4_RS02035
uniprot id: M1WLC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1322246:BN4 RS09025
gene id: 1322246:BN4_RS09025
uniprot id: M1WQL4
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS15550
gene id: 1322246:BN4_RS15550
uniprot id: M1WNF5
names: Similarity
messages: Belongs to the AOR/FOR family.

1322246:BN4 RS10660
gene id: 1322246:BN4_RS10660
uniprot id: M1WWW2
names: Similarity
messages: Belongs to the GARS family.

1322246:BN4 RS04160
gene id: 1322246:BN4_RS04160
uniprot id: M1WLL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1322246:BN4 RS01920
gene id: 1322246:BN4_RS01920
uniprot id: M1WUM7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS13565
gene id: 1322246:BN4_RS13565
uniprot id: M1WMS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1322246:BN4 RS13700
gene id: 1322246:BN4_RS13700
uniprot id: M1WKP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1322246:BN4 RS05400
gene id: 1322246:BN4_RS05400
uniprot id: M1WRH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemerythrin family.
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1322246:BN4 RS05355
gene id: 1322246:BN4_RS05355
uniprot id: M1WRH0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1322246:BN4 RS01945
gene id: 1322246:BN4_RS01945
uniprot id: M1WUM8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1322246:BN4 RS00605
gene id: 1322246:BN4_RS00605
uniprot id: M1WL70
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1322246:BN4 RS02990
gene id: 1322246:BN4_RS02990
uniprot id: M1WUS0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1322246:BN4 RS16740
gene id: 1322246:BN4_RS16740
uniprot id: M1WNS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1322246:BN4 RS02190
gene id: 1322246:BN4_RS02190
uniprot id: M1WUN7
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1322246:BN4 RS14900
gene id: 1322246:BN4_RS14900
uniprot id: M1WU36
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1322246:BN4 RS13315
gene id: 1322246:BN4_RS13315
uniprot id: M1WKN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1322246:BN4 RS00340
gene id: 1322246:BN4_RS00340
uniprot id: M1WJ54
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1322246:BN4 RS10840
gene id: 1322246:BN4_RS10840
uniprot id: M1WKD1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1322246:BN4 RS16440
gene id: 1322246:BN4_RS16440
uniprot id: M1WYQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1322246:BN4 RS01300
gene id: 1322246:BN4_RS01300
uniprot id: M1WL98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1322246:BN4 RS15620
gene id: 1322246:BN4_RS15620
uniprot id: M1WU82
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1322246:BN4 RS03860
gene id: 1322246:BN4_RS03860
uniprot id: M1WP30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1322246:BN4 RS00155
gene id: 1322246:BN4_RS00155
uniprot id: M1WJ46
names: Similarity
messages: Belongs to the peptidase M16 family.

1322246:BN4 RS00840
gene id: 1322246:BN4_RS00840
uniprot id: M1WQ17
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1322246:BN4 RS12585
gene id: 1322246:BN4_RS12585
uniprot id: M1WXH8
names: Similarity
messages: Belongs to the FBPase class 2 family.

1322246:BN4 RS07040
gene id: 1322246:BN4_RS07040
uniprot id: M1WJX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1322246:BN4 RS14950
gene id: 1322246:BN4_RS14950
uniprot id: M1WKU5
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS01900
gene id: 1322246:BN4_RS01900
uniprot id: M1WNI4
names: Subcellular Location Annotation
messages: Cytoplasm

1322246:BN4 RS08740
gene id: 1322246:BN4_RS08740
uniprot id: M1WSM6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1322246:BN4 RS16410
gene id: 1322246:BN4_RS16410
uniprot id: M1WUB5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1322246:BN4 RS11530
gene id: 1322246:BN4_RS11530
uniprot id: M1WMF8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1322246:BN4 RS04655
gene id: 1322246:BN4_RS04655
uniprot id: M1WV41
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1322246:BN4 RS09115
gene id: 1322246:BN4_RS09115
uniprot id: M1WWB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1322246:BN4 RS05470
gene id: 1322246:BN4_RS05470
uniprot id: M1WLR5
names: Similarity
messages: Belongs to the ribF family.

1322246:BN4 RS13325
gene id: 1322246:BN4_RS13325
uniprot id: M1WXS9
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1322246:BN4 RS14465
gene id: 1322246:BN4_RS14465
uniprot id: M1WKS4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1322246:BN4 RS08035
gene id: 1322246:BN4_RS08035
uniprot id: M1WSD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1322246:BN4 RS12310
gene id: 1322246:BN4_RS12310
uniprot id: M1WRP3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1322246:BN4 RS16535
gene id: 1322246:BN4_RS16535
uniprot id: M1WT01
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1322246:BN4 RS08375
gene id: 1322246:BN4_RS08375
uniprot id: M1WM33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1322246:BN4 RS01590
gene id: 1322246:BN4_RS01590
uniprot id: M1WNF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1322246:BN4 RS13355
gene id: 1322246:BN4_RS13355
uniprot id: M1WXT1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1322246:BN4 RS08535
gene id: 1322246:BN4_RS08535
uniprot id: M1WSK5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS02130
gene id: 1322246:BN4_RS02130
uniprot id: M1WJC3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1322246:BN4 RS01700
gene id: 1322246:BN4_RS01700
uniprot id: M1WJA6
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1322246:BN4 RS15525
gene id: 1322246:BN4_RS15525
uniprot id: M1WNF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS12740
gene id: 1322246:BN4_RS12740
uniprot id: M1WTN4
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS08610
gene id: 1322246:BN4_RS08610
uniprot id: M1WSL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS03820
gene id: 1322246:BN4_RS03820
uniprot id: M1WJJ0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1322246:BN4 RS15075
gene id: 1322246:BN4_RS15075
uniprot id: M1WKV0
names: Similarity
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.

1322246:BN4 RS05940
gene id: 1322246:BN4_RS05940
uniprot id: M1WVG3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1322246:BN4 RS16610
gene id: 1322246:BN4_RS16610
uniprot id: M1WT09
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1322246:BN4 RS10395
gene id: 1322246:BN4_RS10395
uniprot id: M1WT64
names: Similarity
messages: Belongs to the asparagine synthetase family.

1322246:BN4 RS15435
gene id: 1322246:BN4_RS15435
uniprot id: M1WSP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1322246:BN4 RS01340
gene id: 1322246:BN4_RS01340
uniprot id: M1WUK5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1322246:BN4 RS12900
gene id: 1322246:BN4_RS12900
uniprot id: M1WRW3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS00660
gene id: 1322246:BN4_RS00660
uniprot id: M1WJ66
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1322246:BN4 RS10100
gene id: 1322246:BN4_RS10100
uniprot id: M1WQY1
names: Similarity
messages: Belongs to the MotB family.

1322246:BN4 RS16275
gene id: 1322246:BN4_RS16275
uniprot id: M1WNN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS16580
gene id: 1322246:BN4_RS16580
uniprot id: M1WYR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1322246:BN4 RS03390
gene id: 1322246:BN4_RS03390
uniprot id: M1WQV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1322246:BN4 RS10295
gene id: 1322246:BN4_RS10295
uniprot id: M1WT53
names: Similarity
messages: Belongs to the AOR/FOR family.

1322246:BN4 RS11640
gene id: 1322246:BN4_RS11640
uniprot id: M1WRH6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1322246:BN4 RS02595
gene id: 1322246:BN4_RS02595
uniprot id: M1WUQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1322246:BN4 RS09135
gene id: 1322246:BN4_RS09135
uniprot id: M1WSR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1322246:BN4 RS14440
gene id: 1322246:BN4_RS14440
uniprot id: M1WKS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1322246:BN4 RS13940
gene id: 1322246:BN4_RS13940
uniprot id: M1WTY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1322246:BN4 RS03015
gene id: 1322246:BN4_RS03015
uniprot id: M1WUS1
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS01640
gene id: 1322246:BN4_RS01640
uniprot id: M1WNF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1322246:BN4 RS02225
gene id: 1322246:BN4_RS02225
uniprot id: M1WLD3
names: Similarity
messages: Belongs to the MotB family.

1322246:BN4 RS05450
gene id: 1322246:BN4_RS05450
uniprot id: M1WJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1322246:BN4 RS03115
gene id: 1322246:BN4_RS03115
uniprot id: M1WUT1
names: Similarity
messages: Belongs to the CobH/CbiC family.

1322246:BN4 RS00165
gene id: 1322246:BN4_RS00165
uniprot id: M1WUF8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1322246:BN4 RS01200
gene id: 1322246:BN4_RS01200
uniprot id: M1WNB7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1322246:BN4 RS03510
gene id: 1322246:BN4_RS03510
uniprot id: M1WLI4
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1322246:BN4 RS16240
gene id: 1322246:BN4_RS16240
uniprot id: M1WKZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1322246:BN4 RS16180
gene id: 1322246:BN4_RS16180
uniprot id: M1WYN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Belongs to the pseudouridine synthase RluA family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1322246:BN4 RS03935
gene id: 1322246:BN4_RS03935
uniprot id: M1WP36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1322246:BN4 RS15430
gene id: 1322246:BN4_RS15430
uniprot id: M1WYE5
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS04670
gene id: 1322246:BN4_RS04670
uniprot id: M1WJM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1322246:BN4 RS13895
gene id: 1322246:BN4_RS13895
uniprot id: M1WXY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1322246:BN4 RS05780
gene id: 1322246:BN4_RS05780
uniprot id: M1WJS1
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1322246:BN4 RS08070
gene id: 1322246:BN4_RS08070
uniprot id: M1WM20
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1322246:BN4 RS15450
gene id: 1322246:BN4_RS15450
uniprot id: M1WU75
names: Subcellular Location Annotation
messages: Membrane

1322246:BN4 RS08365
gene id: 1322246:BN4_RS08365
uniprot id: M1WW41
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1322246:BN4 RS07890
gene id: 1322246:BN4_RS07890
uniprot id: M1WM13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1322246:BN4 RS01720
gene id: 1322246:BN4_RS01720
uniprot id: M1WLB3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1322246:BN4 RS09760
gene id: 1322246:BN4_RS09760
uniprot id: M1WK89
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1322246:BN4 RS07975
gene id: 1322246:BN4_RS07975
uniprot id: M1WM16
names: Similarity
messages: Belongs to the pyruvate kinase family.

1322246:BN4 RS10740
gene id: 1322246:BN4_RS10740
uniprot id: M1WR71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

1322246:BN4 RS13475
gene id: 1322246:BN4_RS13475
uniprot id: M1WKN6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1322246:BN4 RS16670
gene id: 1322246:BN4_RS16670
uniprot id: M1WL13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1322246:BN4 RS11800
gene id: 1322246:BN4_RS11800
uniprot id: M1WKH0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS11355
gene id: 1322246:BN4_RS11355
uniprot id: M1WKF2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1322246:BN4 RS12770
gene id: 1322246:BN4_RS12770
uniprot id: M1WXL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1322246:BN4 RS10330
gene id: 1322246:BN4_RS10330
uniprot id: M1WWS0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1322246:BN4 RS02370
gene id: 1322246:BN4_RS02370
uniprot id: M1WJD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1322246:BN4 RS16665
gene id: 1322246:BN4_RS16665
uniprot id: M1WNS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1322246:BN4 RS05480
gene id: 1322246:BN4_RS05480
uniprot id: M1WRI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1322246:BN4 RS16735
gene id: 1322246:BN4_RS16735
uniprot id: M1WT25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).