1309411:SY84 RS08265
gene id: 1309411:SY84_RS08265
uniprot id: A0A0F7JLB3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1309411:SY84 RS13905
gene id: 1309411:SY84_RS13905
uniprot id: A0A0F7JRC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1309411:SY84 RS00240
gene id: 1309411:SY84_RS00240
uniprot id: A0A0F7JLD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1309411:SY84 RS07135
gene id: 1309411:SY84_RS07135
uniprot id: A0A0F7JMH8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1309411:SY84 RS12160
gene id: 1309411:SY84_RS12160
uniprot id: A0A0F7JMV0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS12285
gene id: 1309411:SY84_RS12285
uniprot id: A0A0F7JSI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1309411:SY84 RS00750
gene id: 1309411:SY84_RS00750
uniprot id: A0A0F7JLK6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1309411:SY84 RS13345
gene id: 1309411:SY84_RS13345
uniprot id: A0A0F7JUV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1309411:SY84 RS02090
gene id: 1309411:SY84_RS02090
uniprot id: A0A0F7JL24
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1309411:SY84 RS04015
gene id: 1309411:SY84_RS04015
uniprot id: A0A0F7JJN6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1309411:SY84 RS00680
gene id: 1309411:SY84_RS00680
uniprot id: A0A0F7JLJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1309411:SY84 RS06510
gene id: 1309411:SY84_RS06510
uniprot id: A0A0F7JN69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1309411:SY84 RS03025
gene id: 1309411:SY84_RS03025
uniprot id: A0A0F7JKV2
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS00905
gene id: 1309411:SY84_RS00905
uniprot id: A0A0F7JJH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1309411:SY84 RS13350
gene id: 1309411:SY84_RS13350
uniprot id: A0A0F7JSX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1309411:SY84 RS08490
gene id: 1309411:SY84_RS08490
uniprot id: A0A0F7JPA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS00250
gene id: 1309411:SY84_RS00250
uniprot id: A0A0F7JM12
names: Similarity
messages: Belongs to the BshC family.

1309411:SY84 RS10870
gene id: 1309411:SY84_RS10870
uniprot id: A0A0F7JRT5
names: Similarity
messages: Belongs to the Nth/MutY family.

1309411:SY84 RS05115
gene id: 1309411:SY84_RS05115
uniprot id: A0A0F7JMD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1309411:SY84 RS07115
gene id: 1309411:SY84_RS07115
uniprot id: A0A0F7JNJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1309411:SY84 RS10630
gene id: 1309411:SY84_RS10630
uniprot id: A0A0F7JM63
names: Similarity
messages: Belongs to the Dps family.

1309411:SY84 RS13005
gene id: 1309411:SY84_RS13005
uniprot id: A0A0F7JR05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1309411:SY84 RS03380
gene id: 1309411:SY84_RS03380
uniprot id: A0A0F7JN47
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS06860
gene id: 1309411:SY84_RS06860
uniprot id: A0A0F7JME7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1309411:SY84 RS06130
gene id: 1309411:SY84_RS06130
uniprot id: A0A0F7JKG3
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS08410
gene id: 1309411:SY84_RS08410
uniprot id: A0A0F7JQQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1309411:SY84 RS09875
gene id: 1309411:SY84_RS09875
uniprot id: A0A0F7JRP8
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1309411:SY84 RS13705
gene id: 1309411:SY84_RS13705
uniprot id: A0A0F7JT16
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

1309411:SY84 RS04855
gene id: 1309411:SY84_RS04855
uniprot id: A0A0F7JK42
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1309411:SY84 RS10030
gene id: 1309411:SY84_RS10030
uniprot id: A0A0F7JRB0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1309411:SY84 RS02520
gene id: 1309411:SY84_RS02520
uniprot id: A0A0F7JMU4
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS11790
gene id: 1309411:SY84_RS11790
uniprot id: A0A0F7JPF4
names: Similarity
messages: Belongs to the IMPACT family.

1309411:SY84 RS10050
gene id: 1309411:SY84_RS10050
uniprot id: A0A0F7JV32
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1309411:SY84 RS09505
gene id: 1309411:SY84_RS09505
uniprot id: A0A0F7JSU1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1309411:SY84 RS14220
gene id: 1309411:SY84_RS14220
uniprot id: A0A0F7JQE2
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS11075
gene id: 1309411:SY84_RS11075
uniprot id: A0A0F7JP15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1309411:SY84 RS03735
gene id: 1309411:SY84_RS03735
uniprot id: A0A0F7JJK5
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1309411:SY84 RS07475
gene id: 1309411:SY84_RS07475
uniprot id: A0A0F7JQV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1309411:SY84 RS04525
gene id: 1309411:SY84_RS04525
uniprot id: A0A0F7JJX2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1309411:SY84 RS10970
gene id: 1309411:SY84_RS10970
uniprot id: A0A0F7JMB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS07195
gene id: 1309411:SY84_RS07195
uniprot id: A0A0F7JPZ7
names: Similarity
messages: Belongs to the peptidase S9C family.

1309411:SY84 RS09235
gene id: 1309411:SY84_RS09235
uniprot id: A0A0F7JRK2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1309411:SY84 RS03195
gene id: 1309411:SY84_RS03195
uniprot id: A0A0F7JNN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1309411:SY84 RS14760
gene id: 1309411:SY84_RS14760
uniprot id: A0A0F7JTT9
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1309411:SY84 RS09600
gene id: 1309411:SY84_RS09600
uniprot id: A0A0F7JRN2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1309411:SY84 RS00760
gene id: 1309411:SY84_RS00760
uniprot id: A0A0F7JMD2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1309411:SY84 RS05525
gene id: 1309411:SY84_RS05525
uniprot id: A0A0F7JML1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1309411:SY84 RS00390
gene id: 1309411:SY84_RS00390
uniprot id: A0A0F7JJ88
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS08220
gene id: 1309411:SY84_RS08220
uniprot id: A0A0F7JR76
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS09240
gene id: 1309411:SY84_RS09240
uniprot id: A0A0F7JLQ5
names: Similarity
messages: Belongs to the threonine synthase family.

1309411:SY84 RS01135
gene id: 1309411:SY84_RS01135
uniprot id: A0A0F7JJK9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1309411:SY84 RS07200
gene id: 1309411:SY84_RS07200
uniprot id: A0A0F7JNL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1309411:SY84 RS05025
gene id: 1309411:SY84_RS05025
uniprot id: A0A0F7JMC6
names: Similarity
messages: Belongs to the peptidase M17 family.

1309411:SY84 RS11700
gene id: 1309411:SY84_RS11700
uniprot id: A0A0F7JQM6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1309411:SY84 RS13065
gene id: 1309411:SY84_RS13065
uniprot id: A0A0F7JR15
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1309411:SY84 RS12365
gene id: 1309411:SY84_RS12365
uniprot id: A0A0F7JQS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1309411:SY84 RS11240
gene id: 1309411:SY84_RS11240
uniprot id: A0A0F7JS86
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS15540
gene id: 1309411:SY84_RS15540
uniprot id: A0A0F7JU69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1309411:SY84 RS14915
gene id: 1309411:SY84_RS14915
uniprot id: A0A0F7JNZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1309411:SY84 RS10780
gene id: 1309411:SY84_RS10780
uniprot id: A0A0F7JNW7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1309411:SY84 RS09125
gene id: 1309411:SY84_RS09125
uniprot id: A0A0F7JLQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS15295
gene id: 1309411:SY84_RS15295
uniprot id: A0A0F7JP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS11710
gene id: 1309411:SY84_RS11710
uniprot id: A0A0F7JV72
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1309411:SY84 RS14885
gene id: 1309411:SY84_RS14885
uniprot id: A0A0F7JNZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1309411:SY84 RS02585
gene id: 1309411:SY84_RS02585
uniprot id: A0A0F7JLF7
names: Cofactor
messages: Binds 1 FAD per subunit.

1309411:SY84 RS07440
gene id: 1309411:SY84_RS07440
uniprot id: A0A0F7JNS5
names: Similarity
messages: Belongs to the peptidase S51 family.

1309411:SY84 RS03920
gene id: 1309411:SY84_RS03920
uniprot id: A0A0F7JNY1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1309411:SY84 RS07350
gene id: 1309411:SY84_RS07350
uniprot id: A0A0F7JQT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1309411:SY84 RS07250
gene id: 1309411:SY84_RS07250
uniprot id: A0A0F7JQ02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1309411:SY84 RS05835
gene id: 1309411:SY84_RS05835
uniprot id: A0A0F7JPB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS01865
gene id: 1309411:SY84_RS01865
uniprot id: A0A0F7JKZ6
names: Similarity
messages: Belongs to the arginase family.

1309411:SY84 RS12710
gene id: 1309411:SY84_RS12710
uniprot id: A0A0F7JQW1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS08500
gene id: 1309411:SY84_RS08500
uniprot id: A0A0F7JLH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS09425
gene id: 1309411:SY84_RS09425
uniprot id: A0A0F7JR55
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1309411:SY84 RS10615
gene id: 1309411:SY84_RS10615
uniprot id: A0A0F7JRL0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1309411:SY84 RS00945
gene id: 1309411:SY84_RS00945
uniprot id: A0A0F7JMF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS07675
gene id: 1309411:SY84_RS07675
uniprot id: A0A0F7JNV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1309411:SY84 RS01015
gene id: 1309411:SY84_RS01015
uniprot id: A0A0F7JJI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1309411:SY84 RS01790
gene id: 1309411:SY84_RS01790
uniprot id: A0A0F7JIY1
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS13375
gene id: 1309411:SY84_RS13375
uniprot id: A0A0F7JSX7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1309411:SY84 RS06260
gene id: 1309411:SY84_RS06260
uniprot id: A0A0F7JQJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1309411:SY84 RS13880
gene id: 1309411:SY84_RS13880
uniprot id: A0A0F7JTC4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1309411:SY84 RS02205
gene id: 1309411:SY84_RS02205
uniprot id: A0A0F7JK27
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS03595
gene id: 1309411:SY84_RS03595
uniprot id: A0A0F7JJJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1309411:SY84 RS09360
gene id: 1309411:SY84_RS09360
uniprot id: A0A0F7JR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1309411:SY84 RS03625
gene id: 1309411:SY84_RS03625
uniprot id: A0A0F7JSF4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1309411:SY84 RS11865
gene id: 1309411:SY84_RS11865
uniprot id: A0A0F7JSL5
names: Similarity
messages: Belongs to the WrbA family.

1309411:SY84 RS09080
gene id: 1309411:SY84_RS09080
uniprot id: A0A0F7JRJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1309411:SY84 RS08975
gene id: 1309411:SY84_RS08975
uniprot id: A0A0F7JLP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS02545
gene id: 1309411:SY84_RS02545
uniprot id: A0A0F7JJ76
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1309411:SY84 RS06750
gene id: 1309411:SY84_RS06750
uniprot id: A0A0F7JMC2
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS15600
gene id: 1309411:SY84_RS15600
uniprot id: A0A0F7JU78
names: Similarity
messages: Belongs to the UPF0225 family.

1309411:SY84 RS03370
gene id: 1309411:SY84_RS03370
uniprot id: A0A0F7JJI0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1309411:SY84 RS06725
gene id: 1309411:SY84_RS06725
uniprot id: A0A0F7JPT9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1309411:SY84 RS01800
gene id: 1309411:SY84_RS01800
uniprot id: A0A0F7JM81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS00025
gene id: 1309411:SY84_RS00025
uniprot id: A0A0F7JIC3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1309411:SY84 RS10075
gene id: 1309411:SY84_RS10075
uniprot id: A0A0F7JRS1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS15435
gene id: 1309411:SY84_RS15435
uniprot id: A0A0F7JQZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1309411:SY84 RS00800
gene id: 1309411:SY84_RS00800
uniprot id: A0A0F7JMD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS00795
gene id: 1309411:SY84_RS00795
uniprot id: A0A0F7JKI7
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1309411:SY84 RS08360
gene id: 1309411:SY84_RS08360
uniprot id: A0A0F7JP89
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1309411:SY84 RS09815
gene id: 1309411:SY84_RS09815
uniprot id: A0A0F7JNK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1309411:SY84 RS14030
gene id: 1309411:SY84_RS14030
uniprot id: A0A0F7JUW4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1309411:SY84 RS14605
gene id: 1309411:SY84_RS14605
uniprot id: A0A0F7JQH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS05100
gene id: 1309411:SY84_RS05100
uniprot id: A0A0F7JK64
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS05825
gene id: 1309411:SY84_RS05825
uniprot id: A0A0F7JKD1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1309411:SY84 RS15495
gene id: 1309411:SY84_RS15495
uniprot id: A0A0F7JR06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

1309411:SY84 RS12230
gene id: 1309411:SY84_RS12230
uniprot id: A0A0F7JPJ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1309411:SY84 RS12500
gene id: 1309411:SY84_RS12500
uniprot id: A0A0F7JPN1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS14355
gene id: 1309411:SY84_RS14355
uniprot id: A0A0F7JTJ7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS05135
gene id: 1309411:SY84_RS05135
uniprot id: A0A0F7JNU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1309411:SY84 RS14940
gene id: 1309411:SY84_RS14940
uniprot id: A0A0F7JS06
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1309411:SY84 RS10595
gene id: 1309411:SY84_RS10595
uniprot id: A0A0F7JUM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1309411:SY84 RS02070
gene id: 1309411:SY84_RS02070
uniprot id: A0A0F7JJZ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS08365
gene id: 1309411:SY84_RS08365
uniprot id: A0A0F7JRB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1309411:SY84 RS11195
gene id: 1309411:SY84_RS11195
uniprot id: A0A0F7JP38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1309411:SY84 RS13245
gene id: 1309411:SY84_RS13245
uniprot id: A0A0F7JPY9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1309411:SY84 RS09040
gene id: 1309411:SY84_RS09040
uniprot id: A0A0F7JPH9
names: Similarity
messages: Belongs to the pyruvate kinase family.

1309411:SY84 RS07170
gene id: 1309411:SY84_RS07170
uniprot id: A0A0F7JNK5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1309411:SY84 RS10170
gene id: 1309411:SY84_RS10170
uniprot id: A0A0F7JRC5
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.

1309411:SY84 RS10440
gene id: 1309411:SY84_RS10440
uniprot id: A0A0F7JNT0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1309411:SY84 RS08115
gene id: 1309411:SY84_RS08115
uniprot id: A0A0F7JR39
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1309411:SY84 RS10690
gene id: 1309411:SY84_RS10690
uniprot id: A0A0F7JM69
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1309411:SY84 RS02245
gene id: 1309411:SY84_RS02245
uniprot id: A0A0F7JMH4
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1309411:SY84 RS02560
gene id: 1309411:SY84_RS02560
uniprot id: A0A0F7JLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1309411:SY84 RS12555
gene id: 1309411:SY84_RS12555
uniprot id: A0A0F7JSW4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1309411:SY84 RS11265
gene id: 1309411:SY84_RS11265
uniprot id: A0A0F7JS90
names: Similarity
messages: Belongs to the NAPRTase family.

1309411:SY84 RS01805
gene id: 1309411:SY84_RS01805
uniprot id: A0A0F7JKY3
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS04020
gene id: 1309411:SY84_RS04020
uniprot id: A0A0F7JL82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1309411:SY84 RS09990
gene id: 1309411:SY84_RS09990
uniprot id: A0A0F7JNM2
names: Similarity
messages: Belongs to the DinB family.

1309411:SY84 RS06830
gene id: 1309411:SY84_RS06830
uniprot id: A0A0F7JKP4
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS02365
gene id: 1309411:SY84_RS02365
uniprot id: A0A0F7JMR4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1309411:SY84 RS04355
gene id: 1309411:SY84_RS04355
uniprot id: A0A0F7JM22
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1309411:SY84 RS00445
gene id: 1309411:SY84_RS00445
uniprot id: A0A0F7JIG0
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1309411:SY84 RS09190
gene id: 1309411:SY84_RS09190
uniprot id: A0A0F7JPJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1309411:SY84 RS15015
gene id: 1309411:SY84_RS15015
uniprot id: A0A0F7JTQ7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1309411:SY84 RS07570
gene id: 1309411:SY84_RS07570
uniprot id: A0A0F7JMK4
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1309411:SY84 RS07255
gene id: 1309411:SY84_RS07255
uniprot id: A0A0F7JNM5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1309411:SY84 RS13130
gene id: 1309411:SY84_RS13130
uniprot id: A0A0F7JR44
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1309411:SY84 RS15085
gene id: 1309411:SY84_RS15085
uniprot id: A0A0F7JNZ8
names: Similarity
messages: Belongs to the FemABX family.

1309411:SY84 RS13505
gene id: 1309411:SY84_RS13505
uniprot id: A0A0F7JSZ6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1309411:SY84 RS13725
gene id: 1309411:SY84_RS13725
uniprot id: A0A0F7JND2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1309411:SY84 RS02220
gene id: 1309411:SY84_RS02220
uniprot id: A0A0F7JN06
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1309411:SY84 RS01385
gene id: 1309411:SY84_RS01385
uniprot id: A0A0F7JIS7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS06135
gene id: 1309411:SY84_RS06135
uniprot id: A0A0F7JM57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1309411:SY84 RS11815
gene id: 1309411:SY84_RS11815
uniprot id: A0A0F7JPF5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS03330
gene id: 1309411:SY84_RS03330
uniprot id: A0A0F7JN43
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1309411:SY84 RS05315
gene id: 1309411:SY84_RS05315
uniprot id: A0A0F7JMJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1309411:SY84 RS11215
gene id: 1309411:SY84_RS11215
uniprot id: A0A0F7JS82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1309411:SY84 RS11575
gene id: 1309411:SY84_RS11575
uniprot id: A0A0F7JPE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS12970
gene id: 1309411:SY84_RS12970
uniprot id: A0A0F7JR01
names: Similarity
messages: Belongs to the universal stress protein A family.

1309411:SY84 RS02030
gene id: 1309411:SY84_RS02030
uniprot id: A0A0F7JJZ4
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

1309411:SY84 RS05185
gene id: 1309411:SY84_RS05185
uniprot id: A0A0F7JLK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1309411:SY84 RS15485
gene id: 1309411:SY84_RS15485
uniprot id: A0A0F7JP47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1309411:SY84 RS09435
gene id: 1309411:SY84_RS09435
uniprot id: A0A0F7JRL8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1309411:SY84 RS06110
gene id: 1309411:SY84_RS06110
uniprot id: A0A0F7JM54
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS14740
gene id: 1309411:SY84_RS14740
uniprot id: A0A0F7JTN6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1309411:SY84 RS05735
gene id: 1309411:SY84_RS05735
uniprot id: A0A0F7JMQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1309411:SY84 RS09490
gene id: 1309411:SY84_RS09490
uniprot id: A0A0F7JPN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1309411:SY84 RS13155
gene id: 1309411:SY84_RS13155
uniprot id: A0A0F7JR50
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1309411:SY84 RS13060
gene id: 1309411:SY84_RS13060
uniprot id: A0A0F7JSU9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1309411:SY84 RS12685
gene id: 1309411:SY84_RS12685
uniprot id: A0A0F7JSX6
names: Similarity
messages: Belongs to the peptidase S8 family.

1309411:SY84 RS08945
gene id: 1309411:SY84_RS08945
uniprot id: A0A0F7JLN8
names: Similarity
messages: Belongs to the ParB family.

1309411:SY84 RS08215
gene id: 1309411:SY84_RS08215
uniprot id: A0A0F7JUY5
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS11930
gene id: 1309411:SY84_RS11930
uniprot id: A0A0F7JSM1
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS08205
gene id: 1309411:SY84_RS08205
uniprot id: A0A0F7JQI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1309411:SY84 RS11615
gene id: 1309411:SY84_RS11615
uniprot id: A0A0F7JQL9
names: Similarity
messages: Belongs to the UPF0111 family.

1309411:SY84 RS03095
gene id: 1309411:SY84_RS03095
uniprot id: A0A0F7JN20
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS03190
gene id: 1309411:SY84_RS03190
uniprot id: A0A0F7JLN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS08620
gene id: 1309411:SY84_RS08620
uniprot id: A0A0F7JN50
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1309411:SY84 RS01250
gene id: 1309411:SY84_RS01250
uniprot id: A0A0F7JML6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1309411:SY84 RS12515
gene id: 1309411:SY84_RS12515
uniprot id: A0A0F7JQU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1309411:SY84 RS05555
gene id: 1309411:SY84_RS05555
uniprot id: A0A0F7JP62
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1309411:SY84 RS02510
gene id: 1309411:SY84_RS02510
uniprot id: A0A0F7JJ75
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS08160
gene id: 1309411:SY84_RS08160
uniprot id: A0A0F7JPM2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1309411:SY84 RS02765
gene id: 1309411:SY84_RS02765
uniprot id: A0A0F7JU87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1309411:SY84 RS13910
gene id: 1309411:SY84_RS13910
uniprot id: A0A0F7JTC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1309411:SY84 RS08455
gene id: 1309411:SY84_RS08455
uniprot id: A0A0F7JPA3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1309411:SY84 RS05740
gene id: 1309411:SY84_RS05740
uniprot id: A0A0F7JQB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1309411:SY84 RS07430
gene id: 1309411:SY84_RS07430
uniprot id: A0A0F7JQ45
names: Similarity
messages: Belongs to the peptidase U62 family.

1309411:SY84 RS13770
gene id: 1309411:SY84_RS13770
uniprot id: A0A0F7JQ43
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1309411:SY84 RS04530
gene id: 1309411:SY84_RS04530
uniprot id: A0A0F7JLB6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1309411:SY84 RS03240
gene id: 1309411:SY84_RS03240
uniprot id: A0A0F7JN37
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS11610
gene id: 1309411:SY84_RS11610
uniprot id: A0A0F7JSB1
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS13305
gene id: 1309411:SY84_RS13305
uniprot id: A0A0F7JPZ5
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1309411:SY84 RS04500
gene id: 1309411:SY84_RS04500
uniprot id: A0A0F7JLB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS06340
gene id: 1309411:SY84_RS06340
uniprot id: A0A0F7JKI9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1309411:SY84 RS03530
gene id: 1309411:SY84_RS03530
uniprot id: A0A0F7JL26
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1309411:SY84 RS07230
gene id: 1309411:SY84_RS07230
uniprot id: A0A0F7JQS3
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS08140
gene id: 1309411:SY84_RS08140
uniprot id: A0A0F7JP33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1309411:SY84 RS12865
gene id: 1309411:SY84_RS12865
uniprot id: A0A0F7JPS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1309411:SY84 RS15050
gene id: 1309411:SY84_RS15050
uniprot id: A0A0F7JTR1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1309411:SY84 RS03715
gene id: 1309411:SY84_RS03715
uniprot id: A0A0F7JN71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

1309411:SY84 RS01425
gene id: 1309411:SY84_RS01425
uniprot id: A0A0F7JJP7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS01875
gene id: 1309411:SY84_RS01875
uniprot id: A0A0F7JIZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1309411:SY84 RS09985
gene id: 1309411:SY84_RS09985
uniprot id: A0A0F7JLZ7
names: Similarity
messages: Belongs to the DinB family.

1309411:SY84 RS04145
gene id: 1309411:SY84_RS04145
uniprot id: A0A0F7JNE9
names: Similarity
messages: Belongs to the SCO1/2 family.

1309411:SY84 RS09710
gene id: 1309411:SY84_RS09710
uniprot id: A0A0F7JPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1309411:SY84 RS11820
gene id: 1309411:SY84_RS11820
uniprot id: A0A0F7JSD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS12925
gene id: 1309411:SY84_RS12925
uniprot id: A0A0F7JPV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1309411:SY84 RS14610
gene id: 1309411:SY84_RS14610
uniprot id: A0A0F7JTR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS05650
gene id: 1309411:SY84_RS05650
uniprot id: A0A0F7JP85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1309411:SY84 RS00040
gene id: 1309411:SY84_RS00040
uniprot id: A0A0F7JKA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1309411:SY84 RS09745
gene id: 1309411:SY84_RS09745
uniprot id: A0A0F7JR83
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1309411:SY84 RS11775
gene id: 1309411:SY84_RS11775
uniprot id: A0A0F7JSK4
names: Similarity
messages: Belongs to the DinB family.

1309411:SY84 RS03490
gene id: 1309411:SY84_RS03490
uniprot id: A0A0F7JJJ4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1309411:SY84 RS07925
gene id: 1309411:SY84_RS07925
uniprot id: A0A0F7JP03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

1309411:SY84 RS02570
gene id: 1309411:SY84_RS02570
uniprot id: A0A0F7JJ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1309411:SY84 RS11855
gene id: 1309411:SY84_RS11855
uniprot id: A0A0F7JSE3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1309411:SY84 RS11410
gene id: 1309411:SY84_RS11410
uniprot id: A0A0F7JP92
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1309411:SY84 RS07285
gene id: 1309411:SY84_RS07285
uniprot id: A0A0F7JNP7
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

1309411:SY84 RS12890
gene id: 1309411:SY84_RS12890
uniprot id: A0A0F7JN00
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1309411:SY84 RS10980
gene id: 1309411:SY84_RS10980
uniprot id: A0A0F7JRV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS14080
gene id: 1309411:SY84_RS14080
uniprot id: A0A0F7JRF8
names: Similarity
messages: Belongs to the peptidase S8 family.

1309411:SY84 RS07645
gene id: 1309411:SY84_RS07645
uniprot id: A0A0F7JQ69
names: Similarity
messages: Belongs to the GSP E family.

1309411:SY84 RS12355
gene id: 1309411:SY84_RS12355
uniprot id: A0A0F7JPL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1309411:SY84 RS04365
gene id: 1309411:SY84_RS04365
uniprot id: A0A0F7JP68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS00045
gene id: 1309411:SY84_RS00045
uniprot id: A0A0F7JLV7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1309411:SY84 RS14305
gene id: 1309411:SY84_RS14305
uniprot id: A0A0F7JTH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS06015
gene id: 1309411:SY84_RS06015
uniprot id: A0A0F7JMV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1309411:SY84 RS01200
gene id: 1309411:SY84_RS01200
uniprot id: A0A0F7JLV0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1309411:SY84 RS08245
gene id: 1309411:SY84_RS08245
uniprot id: A0A0F7JP60
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1309411:SY84 RS08820
gene id: 1309411:SY84_RS08820
uniprot id: A0A0F7JN67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1309411:SY84 RS12995
gene id: 1309411:SY84_RS12995
uniprot id: A0A0F7JPW3
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS05925
gene id: 1309411:SY84_RS05925
uniprot id: A0A0F7JMT8
names: Similarity
messages: Belongs to the XseB family.

1309411:SY84 RS03420
gene id: 1309411:SY84_RS03420
uniprot id: A0A0F7JLT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Membrane

1309411:SY84 RS01030
gene id: 1309411:SY84_RS01030
uniprot id: A0A0F7JMG9
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1309411:SY84 RS06265
gene id: 1309411:SY84_RS06265
uniprot id: A0A0F7JKI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1309411:SY84 RS05545
gene id: 1309411:SY84_RS05545
uniprot id: A0A0F7JSJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1309411:SY84 RS02410
gene id: 1309411:SY84_RS02410
uniprot id: A0A0F7JK76
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS01965
gene id: 1309411:SY84_RS01965
uniprot id: A0A0F7JMW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1309411:SY84 RS07325
gene id: 1309411:SY84_RS07325
uniprot id: A0A0F7JMI5
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1309411:SY84 RS12630
gene id: 1309411:SY84_RS12630
uniprot id: A0A0F7JSM7
names: Subcellular Location Annotation
messages: Cytoplasm

1309411:SY84 RS05645
gene id: 1309411:SY84_RS05645
uniprot id: A0A0F7JLT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1309411:SY84 RS08735
gene id: 1309411:SY84_RS08735
uniprot id: A0A0F7JRF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS08440
gene id: 1309411:SY84_RS08440
uniprot id: A0A0F7JLH1
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS02430
gene id: 1309411:SY84_RS02430
uniprot id: A0A0F7JJ72
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS04600
gene id: 1309411:SY84_RS04600
uniprot id: A0A0F7JJY1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1309411:SY84 RS09690
gene id: 1309411:SY84_RS09690
uniprot id: A0A0F7JRN6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1309411:SY84 RS00460
gene id: 1309411:SY84_RS00460
uniprot id: A0A0F7JKF9
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS04650
gene id: 1309411:SY84_RS04650
uniprot id: A0A0F7JPC7
names: Similarity
messages: Belongs to the ribF family.

1309411:SY84 RS12790
gene id: 1309411:SY84_RS12790
uniprot id: A0A0F7JQX5
names: Similarity
messages: Belongs to the peptidase C56 family.

1309411:SY84 RS00530
gene id: 1309411:SY84_RS00530
uniprot id: A0A0F7JS94
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1309411:SY84 RS10325
gene id: 1309411:SY84_RS10325
uniprot id: A0A0F7JRX8
names: Similarity
messages: Belongs to the aldose epimerase family.

1309411:SY84 RS04265
gene id: 1309411:SY84_RS04265
uniprot id: A0A0F7JP57
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1309411:SY84 RS15180
gene id: 1309411:SY84_RS15180
uniprot id: A0A0F7JS36
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1309411:SY84 RS15140
gene id: 1309411:SY84_RS15140
uniprot id: A0A0F7JQV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1309411:SY84 RS07205
gene id: 1309411:SY84_RS07205
uniprot id: A0A0F7JQS0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1309411:SY84 RS10290
gene id: 1309411:SY84_RS10290
uniprot id: A0A0F7JRD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS07365
gene id: 1309411:SY84_RS07365
uniprot id: A0A0F7JQ39
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS01050
gene id: 1309411:SY84_RS01050
uniprot id: A0A0F7JLR4
names: Similarity
messages: Belongs to the aspartokinase family.

1309411:SY84 RS03990
gene id: 1309411:SY84_RS03990
uniprot id: A0A0F7JL81
names: Similarity
messages: Belongs to the threonine aldolase family.

1309411:SY84 RS14210
gene id: 1309411:SY84_RS14210
uniprot id: A0A0F7JTF6
names: Similarity
messages: Belongs to the AHA1 family.

1309411:SY84 RS04560
gene id: 1309411:SY84_RS04560
uniprot id: A0A0F7JNM3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1309411:SY84 RS03250
gene id: 1309411:SY84_RS03250
uniprot id: A0A0F7JLP7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1309411:SY84 RS13960
gene id: 1309411:SY84_RS13960
uniprot id: A0A0F7JTD0
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1309411:SY84 RS07600
gene id: 1309411:SY84_RS07600
uniprot id: A0A0F7JQX1
names: Similarity
messages: Belongs to the peptidase S8 family.

1309411:SY84 RS14895
gene id: 1309411:SY84_RS14895
uniprot id: A0A0F7JQS5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS12625
gene id: 1309411:SY84_RS12625
uniprot id: A0A0F7JPP4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1309411:SY84 RS06030
gene id: 1309411:SY84_RS06030
uniprot id: A0A0F7JKF0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1309411:SY84 RS07920
gene id: 1309411:SY84_RS07920
uniprot id: A0A0F7JQD2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1309411:SY84 RS14715
gene id: 1309411:SY84_RS14715
uniprot id: A0A0F7JNX1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1309411:SY84 RS12005
gene id: 1309411:SY84_RS12005
uniprot id: A0A0F7JQP0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1309411:SY84 RS11500
gene id: 1309411:SY84_RS11500
uniprot id: A0A0F7JSB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS13040
gene id: 1309411:SY84_RS13040
uniprot id: A0A0F7JUU6
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS14860
gene id: 1309411:SY84_RS14860
uniprot id: A0A0F7JNZ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1309411:SY84 RS13360
gene id: 1309411:SY84_RS13360
uniprot id: A0A0F7JT72
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1309411:SY84 RS08165
gene id: 1309411:SY84_RS08165
uniprot id: A0A0F7JQH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1309411:SY84 RS09480
gene id: 1309411:SY84_RS09480
uniprot id: A0A0F7JNF6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1309411:SY84 RS09975
gene id: 1309411:SY84_RS09975
uniprot id: A0A0F7JPT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1309411:SY84 RS09950
gene id: 1309411:SY84_RS09950
uniprot id: A0A0F7JPT1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1309411:SY84 RS04110
gene id: 1309411:SY84_RS04110
uniprot id: A0A0F7JL85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1309411:SY84 RS04160
gene id: 1309411:SY84_RS04160
uniprot id: A0A0F7JJQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS05725
gene id: 1309411:SY84_RS05725
uniprot id: A0A0F7JLU7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1309411:SY84 RS07540
gene id: 1309411:SY84_RS07540
uniprot id: A0A0F7JL08
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS04280
gene id: 1309411:SY84_RS04280
uniprot id: A0A0F7JNI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS08850
gene id: 1309411:SY84_RS08850
uniprot id: A0A0F7JQY1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1309411:SY84 RS11160
gene id: 1309411:SY84_RS11160
uniprot id: A0A0F7JMD8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1309411:SY84 RS12325
gene id: 1309411:SY84_RS12325
uniprot id: A0A0F7JMW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1309411:SY84 RS01490
gene id: 1309411:SY84_RS01490
uniprot id: A0A0F7JKU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1309411:SY84 RS01400
gene id: 1309411:SY84_RS01400
uniprot id: A0A0F7JM19
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1309411:SY84 RS09510
gene id: 1309411:SY84_RS09510
uniprot id: A0A0F7JNH1
names: Similarity
messages: Belongs to the CinA family.

1309411:SY84 RS01450
gene id: 1309411:SY84_RS01450
uniprot id: A0A0F7JJQ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1309411:SY84 RS02450
gene id: 1309411:SY84_RS02450
uniprot id: A0A0F7JNA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1309411:SY84 RS02015
gene id: 1309411:SY84_RS02015
uniprot id: A0A0F7JMW8
names: Similarity
messages: Belongs to the Skp family.

1309411:SY84 RS04175
gene id: 1309411:SY84_RS04175
uniprot id: A0A0F7JNF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1309411:SY84 RS11115
gene id: 1309411:SY84_RS11115
uniprot id: A0A0F7JQA2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1309411:SY84 RS11125
gene id: 1309411:SY84_RS11125
uniprot id: A0A0F7JMD5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1309411:SY84 RS07070
gene id: 1309411:SY84_RS07070
uniprot id: A0A0F7JMH2
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.

1309411:SY84 RS02280
gene id: 1309411:SY84_RS02280
uniprot id: A0A0F7JMQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1309411:SY84 RS06895
gene id: 1309411:SY84_RS06895
uniprot id: A0A0F7JPV9
names: Similarity
messages: Belongs to the peptidase S1C family.

1309411:SY84 RS10005
gene id: 1309411:SY84_RS10005
uniprot id: A0A0F7JRR6
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1309411:SY84 RS02870
gene id: 1309411:SY84_RS02870
uniprot id: A0A0F7JNH2
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS10765
gene id: 1309411:SY84_RS10765
uniprot id: A0A0F7JQ20
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1309411:SY84 RS03875
gene id: 1309411:SY84_RS03875
uniprot id: A0A0F7JL66
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS14405
gene id: 1309411:SY84_RS14405
uniprot id: A0A0F7JQF4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1309411:SY84 RS02760
gene id: 1309411:SY84_RS02760
uniprot id: A0A0F7JJB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1309411:SY84 RS04140
gene id: 1309411:SY84_RS04140
uniprot id: A0A0F7JL86
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1309411:SY84 RS10235
gene id: 1309411:SY84_RS10235
uniprot id: A0A0F7JM17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1309411:SY84 RS15460
gene id: 1309411:SY84_RS15460
uniprot id: A0A0F7JR02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Catalyzes the phosphorylation of LysW-gamma-alpha-aminoadipate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS14225
gene id: 1309411:SY84_RS14225
uniprot id: A0A0F7JTG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1309411:SY84 RS08740
gene id: 1309411:SY84_RS08740
uniprot id: A0A0F7JLK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1309411:SY84 RS12345
gene id: 1309411:SY84_RS12345
uniprot id: A0A0F7JST6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1309411:SY84 RS00205
gene id: 1309411:SY84_RS00205
uniprot id: A0A0F7JLD3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1309411:SY84 RS09155
gene id: 1309411:SY84_RS09155
uniprot id: A0A0F7JRJ9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1309411:SY84 RS04495
gene id: 1309411:SY84_RS04495
uniprot id: A0A0F7JJW8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1309411:SY84 RS00135
gene id: 1309411:SY84_RS00135
uniprot id: A0A0F7JLC8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1309411:SY84 RS14250
gene id: 1309411:SY84_RS14250
uniprot id: A0A0F7JNH0
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS12800
gene id: 1309411:SY84_RS12800
uniprot id: A0A0F7JSY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1309411:SY84 RS12650
gene id: 1309411:SY84_RS12650
uniprot id: A0A0F7JMY4
names: Similarity
messages: Belongs to the UPF0047 family.

1309411:SY84 RS06145
gene id: 1309411:SY84_RS06145
uniprot id: A0A0F7JN07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1309411:SY84 RS08900
gene id: 1309411:SY84_RS08900
uniprot id: A0A0F7JN85
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1309411:SY84 RS10085
gene id: 1309411:SY84_RS10085
uniprot id: A0A0F7JM03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1309411:SY84 RS05120
gene id: 1309411:SY84_RS05120
uniprot id: A0A0F7JPM0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1309411:SY84 RS03280
gene id: 1309411:SY84_RS03280
uniprot id: A0A0F7JKZ1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1309411:SY84 RS05470
gene id: 1309411:SY84_RS05470
uniprot id: A0A0F7JQ27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1309411:SY84 RS02330
gene id: 1309411:SY84_RS02330
uniprot id: A0A0F7JK54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1309411:SY84 RS03035
gene id: 1309411:SY84_RS03035
uniprot id: A0A0F7JN13
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1309411:SY84 RS02380
gene id: 1309411:SY84_RS02380
uniprot id: A0A0F7JJ70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1309411:SY84 RS03935
gene id: 1309411:SY84_RS03935
uniprot id: A0A0F7JN99
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1309411:SY84 RS15360
gene id: 1309411:SY84_RS15360
uniprot id: A0A0F7JS57
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1309411:SY84 RS08110
gene id: 1309411:SY84_RS08110
uniprot id: A0A0F7JP29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1309411:SY84 RS02860
gene id: 1309411:SY84_RS02860
uniprot id: A0A0F7JMZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS13500
gene id: 1309411:SY84_RS13500
uniprot id: A0A0F7JQ17
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1309411:SY84 RS10830
gene id: 1309411:SY84_RS10830
uniprot id: A0A0F7JS38
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1309411:SY84 RS01290
gene id: 1309411:SY84_RS01290
uniprot id: A0A0F7JLW8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS13835
gene id: 1309411:SY84_RS13835
uniprot id: A0A0F7JVB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1309411:SY84 RS08415
gene id: 1309411:SY84_RS08415
uniprot id: A0A0F7JUY7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS11220
gene id: 1309411:SY84_RS11220
uniprot id: A0A0F7JMF2
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS00455
gene id: 1309411:SY84_RS00455
uniprot id: A0A0F7JLE8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1309411:SY84 RS10310
gene id: 1309411:SY84_RS10310
uniprot id: A0A0F7JNP9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1309411:SY84 RS13680
gene id: 1309411:SY84_RS13680
uniprot id: A0A0F7JT95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1309411:SY84 RS04810
gene id: 1309411:SY84_RS04810
uniprot id: A0A0F7JLE0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1309411:SY84 RS02725
gene id: 1309411:SY84_RS02725
uniprot id: A0A0F7JNE2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1309411:SY84 RS00035
gene id: 1309411:SY84_RS00035
uniprot id: A0A0F7JLA8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1309411:SY84 RS05990
gene id: 1309411:SY84_RS05990
uniprot id: A0A0F7JQD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS09345
gene id: 1309411:SY84_RS09345
uniprot id: A0A0F7JLQ9
names: Similarity
messages: Belongs to the peptidase M29 family.

1309411:SY84 RS10580
gene id: 1309411:SY84_RS10580
uniprot id: A0A0F7JQ00
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1309411:SY84 RS10835
gene id: 1309411:SY84_RS10835
uniprot id: A0A0F7JM75
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1309411:SY84 RS11475
gene id: 1309411:SY84_RS11475
uniprot id: A0A0F7JPA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1309411:SY84 RS09760
gene id: 1309411:SY84_RS09760
uniprot id: A0A0F7JLW3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS10230
gene id: 1309411:SY84_RS10230
uniprot id: A0A0F7JRT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1309411:SY84 RS14255
gene id: 1309411:SY84_RS14255
uniprot id: A0A0F7JQE4
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS00345
gene id: 1309411:SY84_RS00345
uniprot id: A0A0F7JKD8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1309411:SY84 RS12260
gene id: 1309411:SY84_RS12260
uniprot id: A0A0F7JSH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1309411:SY84 RS10585
gene id: 1309411:SY84_RS10585
uniprot id: A0A0F7JS07
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1309411:SY84 RS06900
gene id: 1309411:SY84_RS06900
uniprot id: A0A0F7JNG8
names: Subcellular Location Annotation
messages: Nucleus

1309411:SY84 RS01040
gene id: 1309411:SY84_RS01040
uniprot id: A0A0F7JJJ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1309411:SY84 RS01345
gene id: 1309411:SY84_RS01345
uniprot id: A0A0F7JLZ2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1309411:SY84 RS13555
gene id: 1309411:SY84_RS13555
uniprot id: A0A0F7JNB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1309411:SY84 RS04545
gene id: 1309411:SY84_RS04545
uniprot id: A0A0F7JPB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS11635
gene id: 1309411:SY84_RS11635
uniprot id: A0A0F7JSB5
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS11130
gene id: 1309411:SY84_RS11130
uniprot id: A0A0F7JP28
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1309411:SY84 RS11705
gene id: 1309411:SY84_RS11705
uniprot id: A0A0F7JSJ7
names: Similarity
messages: Belongs to the peptidase S13 family.

1309411:SY84 RS00920
gene id: 1309411:SY84_RS00920
uniprot id: A0A0F7JMF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS02440
gene id: 1309411:SY84_RS02440
uniprot id: A0A0F7JMT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1309411:SY84 RS06080
gene id: 1309411:SY84_RS06080
uniprot id: A0A0F7JUV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1309411:SY84 RS11080
gene id: 1309411:SY84_RS11080
uniprot id: A0A0F7JRW6
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS13210
gene id: 1309411:SY84_RS13210
uniprot id: A0A0F7JSV8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1309411:SY84 RS12350
gene id: 1309411:SY84_RS12350
uniprot id: A0A0F7JMW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1309411:SY84 RS07825
gene id: 1309411:SY84_RS07825
uniprot id: A0A0F7JR04
names: Similarity
messages: Belongs to the asparaginase 1 family.

1309411:SY84 RS14445
gene id: 1309411:SY84_RS14445
uniprot id: A0A0F7JTH3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1309411:SY84 RS02475
gene id: 1309411:SY84_RS02475
uniprot id: A0A0F7JNB4
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS09210
gene id: 1309411:SY84_RS09210
uniprot id: A0A0F7JNC5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS13575
gene id: 1309411:SY84_RS13575
uniprot id: A0A0F7JTC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1309411:SY84 RS00405
gene id: 1309411:SY84_RS00405
uniprot id: A0A0F7JM58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS13395
gene id: 1309411:SY84_RS13395
uniprot id: A0A0F7JQ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1309411:SY84 RS07695
gene id: 1309411:SY84_RS07695
uniprot id: A0A0F7JQ89
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1309411:SY84 RS00955
gene id: 1309411:SY84_RS00955
uniprot id: A0A0F7JJH9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1309411:SY84 RS11665
gene id: 1309411:SY84_RS11665
uniprot id: A0A0F7JQM4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1309411:SY84 RS04915
gene id: 1309411:SY84_RS04915
uniprot id: A0A0F7JLG7
names: Similarity
messages: Belongs to the FGGY kinase family.

1309411:SY84 RS04830
gene id: 1309411:SY84_RS04830
uniprot id: A0A0F7JK25
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1309411:SY84 RS09575
gene id: 1309411:SY84_RS09575
uniprot id: A0A0F7JLT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS05945
gene id: 1309411:SY84_RS05945
uniprot id: A0A0F7JLY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1309411:SY84 RS01855
gene id: 1309411:SY84_RS01855
uniprot id: A0A0F7JJX7
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1309411:SY84 RS14440
gene id: 1309411:SY84_RS14440
uniprot id: A0A0F7JRP9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1309411:SY84 RS12660
gene id: 1309411:SY84_RS12660
uniprot id: A0A0F7JV94
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1309411:SY84 RS09275
gene id: 1309411:SY84_RS09275
uniprot id: A0A0F7JR32
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1309411:SY84 RS13280
gene id: 1309411:SY84_RS13280
uniprot id: A0A0F7JSW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1309411:SY84 RS11120
gene id: 1309411:SY84_RS11120
uniprot id: A0A0F7JS73
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1309411:SY84 RS01100
gene id: 1309411:SY84_RS01100
uniprot id: A0A0F7JIL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1309411:SY84 RS07940
gene id: 1309411:SY84_RS07940
uniprot id: A0A0F7JL68
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1309411:SY84 RS08345
gene id: 1309411:SY84_RS08345
uniprot id: A0A0F7JLG4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1309411:SY84 RS11675
gene id: 1309411:SY84_RS11675
uniprot id: A0A0F7JMN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1309411:SY84 RS08465
gene id: 1309411:SY84_RS08465
uniprot id: A0A0F7JLH2
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1309411:SY84 RS13185
gene id: 1309411:SY84_RS13185
uniprot id: A0A0F7JSV3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1309411:SY84 RS00350
gene id: 1309411:SY84_RS00350
uniprot id: A0A0F7JM40
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS13455
gene id: 1309411:SY84_RS13455
uniprot id: A0A0F7JSY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS08125
gene id: 1309411:SY84_RS08125
uniprot id: A0A0F7JL96
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1309411:SY84 RS07150
gene id: 1309411:SY84_RS07150
uniprot id: A0A0F7JQR5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1309411:SY84 RS02290
gene id: 1309411:SY84_RS02290
uniprot id: A0A0F7JN66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1309411:SY84 RS00235
gene id: 1309411:SY84_RS00235
uniprot id: A0A0F7JJ67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1309411:SY84 RS10750
gene id: 1309411:SY84_RS10750
uniprot id: A0A0F7JM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1309411:SY84 RS03845
gene id: 1309411:SY84_RS03845
uniprot id: A0A0F7JL63
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS05715
gene id: 1309411:SY84_RS05715
uniprot id: A0A0F7JKC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1309411:SY84 RS08495
gene id: 1309411:SY84_RS08495
uniprot id: A0A0F7JRC4
names: Similarity
messages: Belongs to the P(II) protein family.

1309411:SY84 RS12950
gene id: 1309411:SY84_RS12950
uniprot id: A0A0F7JN08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1309411:SY84 RS15425
gene id: 1309411:SY84_RS15425
uniprot id: A0A0F7JTY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS09035
gene id: 1309411:SY84_RS09035
uniprot id: A0A0F7JUK0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1309411:SY84 RS16800
gene id: 1309411:SY84_RS16800
uniprot id: A0A0F7JM49
names: Similarity
messages: Belongs to the peptidase C1 family.

1309411:SY84 RS03960
gene id: 1309411:SY84_RS03960
uniprot id: A0A0F7JL76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS11755
gene id: 1309411:SY84_RS11755
uniprot id: A0A0F7JPF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1309411:SY84 RS13470
gene id: 1309411:SY84_RS13470
uniprot id: A0A0F7JN95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1309411:SY84 RS11340
gene id: 1309411:SY84_RS11340
uniprot id: A0A0F7JP84
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1309411:SY84 RS08630
gene id: 1309411:SY84_RS08630
uniprot id: A0A0F7JRU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1309411:SY84 RS10620
gene id: 1309411:SY84_RS10620
uniprot id: A0A0F7JQ03
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1309411:SY84 RS05670
gene id: 1309411:SY84_RS05670
uniprot id: A0A0F7JLT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1309411:SY84 RS01275
gene id: 1309411:SY84_RS01275
uniprot id: A0A0F7JMM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1309411:SY84 RS04890
gene id: 1309411:SY84_RS04890
uniprot id: A0A0F7JNS0
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS08615
gene id: 1309411:SY84_RS08615
uniprot id: A0A0F7JLH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1309411:SY84 RS08870
gene id: 1309411:SY84_RS08870
uniprot id: A0A0F7JN81
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1309411:SY84 RS15635
gene id: 1309411:SY84_RS15635
uniprot id: A0A0F7JU09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS09030
gene id: 1309411:SY84_RS09030
uniprot id: A0A0F7JR03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1309411:SY84 RS12185
gene id: 1309411:SY84_RS12185
uniprot id: A0A0F7JMV4
names: Similarity
messages: Belongs to the YciI family.

1309411:SY84 RS08935
gene id: 1309411:SY84_RS08935
uniprot id: A0A0F7JPG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1309411:SY84 RS02270
gene id: 1309411:SY84_RS02270
uniprot id: A0A0F7JK44
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1309411:SY84 RS08750
gene id: 1309411:SY84_RS08750
uniprot id: A0A0F7JN58
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1309411:SY84 RS00635
gene id: 1309411:SY84_RS00635
uniprot id: A0A0F7JMB4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1309411:SY84 RS07355
gene id: 1309411:SY84_RS07355
uniprot id: A0A0F7JKW2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1309411:SY84 RS14840
gene id: 1309411:SY84_RS14840
uniprot id: A0A0F7JQP8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1309411:SY84 RS07560
gene id: 1309411:SY84_RS07560
uniprot id: A0A0F7JQW5
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS01395
gene id: 1309411:SY84_RS01395
uniprot id: A0A0F7JP74
names: Similarity
messages: Belongs to the asp23 family.

1309411:SY84 RS07635
gene id: 1309411:SY84_RS07635
uniprot id: A0A0F7JML0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1309411:SY84 RS06240
gene id: 1309411:SY84_RS06240
uniprot id: A0A0F7JM68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1309411:SY84 RS04315
gene id: 1309411:SY84_RS04315
uniprot id: A0A0F7JP63
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS01460
gene id: 1309411:SY84_RS01460
uniprot id: A0A0F7JKU0
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

1309411:SY84 RS15560
gene id: 1309411:SY84_RS15560
uniprot id: A0A0F7JP49
names: Subcellular Location Annotation
messages: Cytoplasm

1309411:SY84 RS12410
gene id: 1309411:SY84_RS12410
uniprot id: A0A0F7JSK3
names: Similarity
messages: Belongs to the citrate synthase family.

1309411:SY84 RS01980
gene id: 1309411:SY84_RS01980
uniprot id: A0A0F7JMD4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1309411:SY84 RS08035
gene id: 1309411:SY84_RS08035
uniprot id: A0A0F7JQE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1309411:SY84 RS12765
gene id: 1309411:SY84_RS12765
uniprot id: A0A0F7JQX0
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS13055
gene id: 1309411:SY84_RS13055
uniprot id: A0A0F7JQ18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1309411:SY84 RS13865
gene id: 1309411:SY84_RS13865
uniprot id: A0A0F7JQ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS05775
gene id: 1309411:SY84_RS05775
uniprot id: A0A0F7JLV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1309411:SY84 RS02600
gene id: 1309411:SY84_RS02600
uniprot id: A0A0F7JKL7
names: Similarity
messages: Belongs to the peptidase S8 family.

1309411:SY84 RS06585
gene id: 1309411:SY84_RS06585
uniprot id: A0A0F7JPS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS05325
gene id: 1309411:SY84_RS05325
uniprot id: A0A0F7JK90
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1309411:SY84 RS02425
gene id: 1309411:SY84_RS02425
uniprot id: A0A0F7JN97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1309411:SY84 RS04295
gene id: 1309411:SY84_RS04295
uniprot id: A0A0F7JJT3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1309411:SY84 RS13915
gene id: 1309411:SY84_RS13915
uniprot id: A0A0F7JUV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1309411:SY84 RS03980
gene id: 1309411:SY84_RS03980
uniprot id: A0A0F7JNY7
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS14410
gene id: 1309411:SY84_RS14410
uniprot id: A0A0F7JTM4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1309411:SY84 RS05230
gene id: 1309411:SY84_RS05230
uniprot id: A0A0F7JPP5
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS00495
gene id: 1309411:SY84_RS00495
uniprot id: A0A0F7JKG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1309411:SY84 RS06745
gene id: 1309411:SY84_RS06745
uniprot id: A0A0F7JKN1
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS08665
gene id: 1309411:SY84_RS08665
uniprot id: A0A0F7JQV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS08915
gene id: 1309411:SY84_RS08915
uniprot id: A0A0F7JRI0
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1309411:SY84 RS06090
gene id: 1309411:SY84_RS06090
uniprot id: A0A0F7JMY0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1309411:SY84 RS03050
gene id: 1309411:SY84_RS03050
uniprot id: A0A0F7JNM7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1309411:SY84 RS04390
gene id: 1309411:SY84_RS04390
uniprot id: A0A0F7JM24
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1309411:SY84 RS12810
gene id: 1309411:SY84_RS12810
uniprot id: A0A0F7JPR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1309411:SY84 RS12860
gene id: 1309411:SY84_RS12860
uniprot id: A0A0F7JMZ8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1309411:SY84 RS05770
gene id: 1309411:SY84_RS05770
uniprot id: A0A0F7JKC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1309411:SY84 RS14155
gene id: 1309411:SY84_RS14155
uniprot id: A0A0F7JTF4
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1309411:SY84 RS11970
gene id: 1309411:SY84_RS11970
uniprot id: A0A0F7JPG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS06155
gene id: 1309411:SY84_RS06155
uniprot id: A0A0F7JKG7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1309411:SY84 RS13310
gene id: 1309411:SY84_RS13310
uniprot id: A0A0F7JSW8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1309411:SY84 RS14615
gene id: 1309411:SY84_RS14615
uniprot id: A0A0F7JRU5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1309411:SY84 RS05295
gene id: 1309411:SY84_RS05295
uniprot id: A0A0F7JQ08
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1309411:SY84 RS15370
gene id: 1309411:SY84_RS15370
uniprot id: A0A0F7JP35
names: Subcellular Location Annotation
messages: Cytoplasm

1309411:SY84 RS09085
gene id: 1309411:SY84_RS09085
uniprot id: A0A0F7JLQ0
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1309411:SY84 RS10525
gene id: 1309411:SY84_RS10525
uniprot id: A0A0F7JRZ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1309411:SY84 RS10405
gene id: 1309411:SY84_RS10405
uniprot id: A0A0F7JRY5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS03725
gene id: 1309411:SY84_RS03725
uniprot id: A0A0F7JLX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1309411:SY84 RS04450
gene id: 1309411:SY84_RS04450
uniprot id: A0A0F7JNK2
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS06275
gene id: 1309411:SY84_RS06275
uniprot id: A0A0F7JPN6
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1309411:SY84 RS02900
gene id: 1309411:SY84_RS02900
uniprot id: A0A0F7JLL0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1309411:SY84 RS15120
gene id: 1309411:SY84_RS15120
uniprot id: A0A0F7JTZ8
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

1309411:SY84 RS07280
gene id: 1309411:SY84_RS07280
uniprot id: A0A0F7JQ26
names: Similarity
messages: Belongs to the universal stress protein A family.

1309411:SY84 RS00490
gene id: 1309411:SY84_RS00490
uniprot id: A0A0F7JLF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1309411:SY84 RS15040
gene id: 1309411:SY84_RS15040
uniprot id: A0A0F7JTH5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1309411:SY84 RS00480
gene id: 1309411:SY84_RS00480
uniprot id: A0A0F7JJA0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1309411:SY84 RS05205
gene id: 1309411:SY84_RS05205
uniprot id: A0A0F7JPN9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1309411:SY84 RS12495
gene id: 1309411:SY84_RS12495
uniprot id: A0A0F7JUS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS05820
gene id: 1309411:SY84_RS05820
uniprot id: A0A0F7JQC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1309411:SY84 RS06285
gene id: 1309411:SY84_RS06285
uniprot id: A0A0F7JRN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1309411:SY84 RS02990
gene id: 1309411:SY84_RS02990
uniprot id: A0A0F7JNL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1309411:SY84 RS03550
gene id: 1309411:SY84_RS03550
uniprot id: A0A0F7JJJ7
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS02120
gene id: 1309411:SY84_RS02120
uniprot id: A0A0F7JR78
names: Similarity
messages: Belongs to the GARS family.

1309411:SY84 RS11430
gene id: 1309411:SY84_RS11430
uniprot id: A0A0F7JSA9
names: Similarity
messages: Belongs to the UPF0102 family.

1309411:SY84 RS14005
gene id: 1309411:SY84_RS14005
uniprot id: A0A0F7JQ66
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1309411:SY84 RS02260
gene id: 1309411:SY84_RS02260
uniprot id: A0A0F7JN10
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1309411:SY84 RS14645
gene id: 1309411:SY84_RS14645
uniprot id: A0A0F7JTJ1
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS05255
gene id: 1309411:SY84_RS05255
uniprot id: A0A0F7JNZ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1309411:SY84 RS07990
gene id: 1309411:SY84_RS07990
uniprot id: A0A0F7JMP8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1309411:SY84 RS03780
gene id: 1309411:SY84_RS03780
uniprot id: A0A0F7JL56
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.

1309411:SY84 RS06675
gene id: 1309411:SY84_RS06675
uniprot id: A0A0F7JKM4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1309411:SY84 RS12335
gene id: 1309411:SY84_RS12335
uniprot id: A0A0F7JSJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1309411:SY84 RS14415
gene id: 1309411:SY84_RS14415
uniprot id: A0A0F7JRP5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1309411:SY84 RS11535
gene id: 1309411:SY84_RS11535
uniprot id: A0A0F7JSA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1309411:SY84 RS05755
gene id: 1309411:SY84_RS05755
uniprot id: A0A0F7JPA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1309411:SY84 RS14795
gene id: 1309411:SY84_RS14795
uniprot id: A0A0F7JRY7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1309411:SY84 RS00300
gene id: 1309411:SY84_RS00300
uniprot id: A0A0F7JIE1
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1309411:SY84 RS11835
gene id: 1309411:SY84_RS11835
uniprot id: A0A0F7JSL2
names: Similarity
messages: Belongs to the peptidase M29 family.

1309411:SY84 RS03585
gene id: 1309411:SY84_RS03585
uniprot id: A0A0F7JLW5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1309411:SY84 RS01860
gene id: 1309411:SY84_RS01860
uniprot id: A0A0F7JMB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1309411:SY84 RS15320
gene id: 1309411:SY84_RS15320
uniprot id: A0A0F7JP26
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1309411:SY84 RS10320
gene id: 1309411:SY84_RS10320
uniprot id: A0A0F7JPW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1309411:SY84 RS00890
gene id: 1309411:SY84_RS00890
uniprot id: A0A0F7JKJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1309411:SY84 RS01020
gene id: 1309411:SY84_RS01020
uniprot id: A0A0F7JLP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1309411:SY84 RS02740
gene id: 1309411:SY84_RS02740
uniprot id: A0A0F7JMY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS14280
gene id: 1309411:SY84_RS14280
uniprot id: A0A0F7JNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1309411:SY84 RS03655
gene id: 1309411:SY84_RS03655
uniprot id: A0A0F7JNU9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1309411:SY84 RS02045
gene id: 1309411:SY84_RS02045
uniprot id: A0A0F7JMX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1309411:SY84 RS14325
gene id: 1309411:SY84_RS14325
uniprot id: A0A0F7JQE8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1309411:SY84 RS11965
gene id: 1309411:SY84_RS11965
uniprot id: A0A0F7JMS4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1309411:SY84 RS07680
gene id: 1309411:SY84_RS07680
uniprot id: A0A0F7JQY3
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS05170
gene id: 1309411:SY84_RS05170
uniprot id: A0A0F7JPN3
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1309411:SY84 RS11060
gene id: 1309411:SY84_RS11060
uniprot id: A0A0F7JQA0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1309411:SY84 RS04895
gene id: 1309411:SY84_RS04895
uniprot id: A0A0F7JMA0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1309411:SY84 RS14380
gene id: 1309411:SY84_RS14380
uniprot id: A0A0F7JTK1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1309411:SY84 RS10140
gene id: 1309411:SY84_RS10140
uniprot id: A0A0F7JNN6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1309411:SY84 RS05090
gene id: 1309411:SY84_RS05090
uniprot id: A0A0F7JPL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1309411:SY84 RS03360
gene id: 1309411:SY84_RS03360
uniprot id: A0A0F7JLR5
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS05260
gene id: 1309411:SY84_RS05260
uniprot id: A0A0F7JPE5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1309411:SY84 RS00580
gene id: 1309411:SY84_RS00580
uniprot id: A0A0F7JLH6
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS02670
gene id: 1309411:SY84_RS02670
uniprot id: A0A0F7JJ92
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1309411:SY84 RS02055
gene id: 1309411:SY84_RS02055
uniprot id: A0A0F7JJ15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1309411:SY84 RS07050
gene id: 1309411:SY84_RS07050
uniprot id: A0A0F7JPJ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1309411:SY84 RS13935
gene id: 1309411:SY84_RS13935
uniprot id: A0A0F7JT67
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1309411:SY84 RS06085
gene id: 1309411:SY84_RS06085
uniprot id: A0A0F7JPG7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1309411:SY84 RS01795
gene id: 1309411:SY84_RS01795
uniprot id: A0A0F7JJX1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1309411:SY84 RS00210
gene id: 1309411:SY84_RS00210
uniprot id: A0A0F7JU96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1309411:SY84 RS13890
gene id: 1309411:SY84_RS13890
uniprot id: A0A0F7JQ55
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS10315
gene id: 1309411:SY84_RS10315
uniprot id: A0A0F7JRE2
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1309411:SY84 RS09090
gene id: 1309411:SY84_RS09090
uniprot id: A0A0F7JNB2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1309411:SY84 RS02350
gene id: 1309411:SY84_RS02350
uniprot id: A0A0F7JJ69
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.

1309411:SY84 RS14290
gene id: 1309411:SY84_RS14290
uniprot id: A0A0F7JVC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1309411:SY84 RS06615
gene id: 1309411:SY84_RS06615
uniprot id: A0A0F7JKL6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1309411:SY84 RS12330
gene id: 1309411:SY84_RS12330
uniprot id: A0A0F7JPL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1309411:SY84 RS02915
gene id: 1309411:SY84_RS02915
uniprot id: A0A0F7JKT8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS10650
gene id: 1309411:SY84_RS10650
uniprot id: A0A0F7JQ05
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1309411:SY84 RS08210
gene id: 1309411:SY84_RS08210
uniprot id: A0A0F7JP56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1309411:SY84 RS13695
gene id: 1309411:SY84_RS13695
uniprot id: A0A0F7JQ37
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1309411:SY84 RS08545
gene id: 1309411:SY84_RS08545
uniprot id: A0A0F7JN46
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1309411:SY84 RS08845
gene id: 1309411:SY84_RS08845
uniprot id: A0A0F7JN77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1309411:SY84 RS14130
gene id: 1309411:SY84_RS14130
uniprot id: A0A0F7JNG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1309411:SY84 RS09160
gene id: 1309411:SY84_RS09160
uniprot id: A0A0F7JLQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1309411:SY84 RS02930
gene id: 1309411:SY84_RS02930
uniprot id: A0A0F7JNK9
names: Similarity
messages: Belongs to the peptidase C40 family.

1309411:SY84 RS05640
gene id: 1309411:SY84_RS05640
uniprot id: A0A0F7JKA8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1309411:SY84 RS04220
gene id: 1309411:SY84_RS04220
uniprot id: A0A0F7JL89
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1309411:SY84 RS02680
gene id: 1309411:SY84_RS02680
uniprot id: A0A0F7JKM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS05685
gene id: 1309411:SY84_RS05685
uniprot id: A0A0F7JQ94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1309411:SY84 RS08040
gene id: 1309411:SY84_RS08040
uniprot id: A0A0F7JP14
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1309411:SY84 RS11235
gene id: 1309411:SY84_RS11235
uniprot id: A0A0F7JQA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1309411:SY84 RS00950
gene id: 1309411:SY84_RS00950
uniprot id: A0A0F7JIK4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1309411:SY84 RS04660
gene id: 1309411:SY84_RS04660
uniprot id: A0A0F7JLC1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1309411:SY84 RS07840
gene id: 1309411:SY84_RS07840
uniprot id: A0A0F7JQC2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1309411:SY84 RS15490
gene id: 1309411:SY84_RS15490
uniprot id: A0A0F7JSJ3
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS11860
gene id: 1309411:SY84_RS11860
uniprot id: A0A0F7JQN1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1309411:SY84 RS01210
gene id: 1309411:SY84_RS01210
uniprot id: A0A0F7JMJ5
names: Similarity
messages: Belongs to the GSP E family.

1309411:SY84 RS05655
gene id: 1309411:SY84_RS05655
uniprot id: A0A0F7JMM0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1309411:SY84 RS07835
gene id: 1309411:SY84_RS07835
uniprot id: A0A0F7JMN1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1309411:SY84 RS08960
gene id: 1309411:SY84_RS08960
uniprot id: A0A0F7JQZ5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1309411:SY84 RS03465
gene id: 1309411:SY84_RS03465
uniprot id: A0A0F7JRF5
names: Similarity
messages: Belongs to the RelA/SpoT family.

1309411:SY84 RS02835
gene id: 1309411:SY84_RS02835
uniprot id: A0A0F7JMZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1309411:SY84 RS15620
gene id: 1309411:SY84_RS15620
uniprot id: A0A0F7JR23
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1309411:SY84 RS14070
gene id: 1309411:SY84_RS14070
uniprot id: A0A0F7JQ87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

1309411:SY84 RS10010
gene id: 1309411:SY84_RS10010
uniprot id: A0A0F7JPS7
names: Similarity
messages: Belongs to the GSP E family.

1309411:SY84 RS12905
gene id: 1309411:SY84_RS12905
uniprot id: A0A0F7JQZ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1309411:SY84 RS10070
gene id: 1309411:SY84_RS10070
uniprot id: A0A0F7JPU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1309411:SY84 RS08055
gene id: 1309411:SY84_RS08055
uniprot id: A0A0F7JMQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1309411:SY84 RS12115
gene id: 1309411:SY84_RS12115
uniprot id: A0A0F7JSG1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1309411:SY84 RS00640
gene id: 1309411:SY84_RS00640
uniprot id: A0A0F7JIH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1309411:SY84 RS15125
gene id: 1309411:SY84_RS15125
uniprot id: A0A0F7JS28
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1309411:SY84 RS07855
gene id: 1309411:SY84_RS07855
uniprot id: A0A0F7JR08
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS08460
gene id: 1309411:SY84_RS08460
uniprot id: A0A0F7JRC1
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1309411:SY84 RS14555
gene id: 1309411:SY84_RS14555
uniprot id: A0A0F7JRT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1309411:SY84 RS15190
gene id: 1309411:SY84_RS15190
uniprot id: A0A0F7JP12
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1309411:SY84 RS14875
gene id: 1309411:SY84_RS14875
uniprot id: A0A0F7JRZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1309411:SY84 RS15450
gene id: 1309411:SY84_RS15450
uniprot id: A0A0F7JTY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1309411:SY84 RS11630
gene id: 1309411:SY84_RS11630
uniprot id: A0A0F7JPE9
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS14385
gene id: 1309411:SY84_RS14385
uniprot id: A0A0F7JRM2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

1309411:SY84 RS13220
gene id: 1309411:SY84_RS13220
uniprot id: A0A0F7JT61
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1309411:SY84 RS07490
gene id: 1309411:SY84_RS07490
uniprot id: A0A0F7JQ50
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1309411:SY84 RS06075
gene id: 1309411:SY84_RS06075
uniprot id: A0A0F7JM39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1309411:SY84 RS05665
gene id: 1309411:SY84_RS05665
uniprot id: A0A0F7JKB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1309411:SY84 RS12730
gene id: 1309411:SY84_RS12730
uniprot id: A0A0F7JSN8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1309411:SY84 RS11320
gene id: 1309411:SY84_RS11320
uniprot id: A0A0F7JQF9
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS03860
gene id: 1309411:SY84_RS03860
uniprot id: A0A0F7JNX3
names: Similarity
messages: Belongs to the PspA/IM30 family.

1309411:SY84 RS14690
gene id: 1309411:SY84_RS14690
uniprot id: A0A0F7JNQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1309411:SY84 RS03850
gene id: 1309411:SY84_RS03850
uniprot id: A0A0F7JN75
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1309411:SY84 RS11230
gene id: 1309411:SY84_RS11230
uniprot id: A0A0F7JRZ8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1309411:SY84 RS06280
gene id: 1309411:SY84_RS06280
uniprot id: A0A0F7JN28
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1309411:SY84 RS04920
gene id: 1309411:SY84_RS04920
uniprot id: A0A0F7JNS1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1309411:SY84 RS05885
gene id: 1309411:SY84_RS05885
uniprot id: A0A0F7JLY3
names: Similarity
messages: Belongs to the peptidase S58 family.

1309411:SY84 RS10280
gene id: 1309411:SY84_RS10280
uniprot id: A0A0F7JM33
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1309411:SY84 RS08390
gene id: 1309411:SY84_RS08390
uniprot id: A0A0F7JRB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1309411:SY84 RS07805
gene id: 1309411:SY84_RS07805
uniprot id: A0A0F7JMM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1309411:SY84 RS10875
gene id: 1309411:SY84_RS10875
uniprot id: A0A0F7JS14
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS10975
gene id: 1309411:SY84_RS10975
uniprot id: A0A0F7JP06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1309411:SY84 RS13080
gene id: 1309411:SY84_RS13080
uniprot id: A0A0F7JPX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS05380
gene id: 1309411:SY84_RS05380
uniprot id: A0A0F7JQ16
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1309411:SY84 RS12390
gene id: 1309411:SY84_RS12390
uniprot id: A0A0F7JST9
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS15135
gene id: 1309411:SY84_RS15135
uniprot id: A0A0F7JP04
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1309411:SY84 RS08990
gene id: 1309411:SY84_RS08990
uniprot id: A0A0F7JNA3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1309411:SY84 RS14195
gene id: 1309411:SY84_RS14195
uniprot id: A0A0F7JQB4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1309411:SY84 RS05320
gene id: 1309411:SY84_RS05320
uniprot id: A0A0F7JQ11
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1309411:SY84 RS07510
gene id: 1309411:SY84_RS07510
uniprot id: A0A0F7JL06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1309411:SY84 RS14575
gene id: 1309411:SY84_RS14575
uniprot id: A0A0F7JTR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1309411:SY84 RS14920
gene id: 1309411:SY84_RS14920
uniprot id: A0A0F7JQS9
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS01265
gene id: 1309411:SY84_RS01265
uniprot id: A0A0F7JLW1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1309411:SY84 RS01360
gene id: 1309411:SY84_RS01360
uniprot id: A0A0F7JIR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1309411:SY84 RS07505
gene id: 1309411:SY84_RS07505
uniprot id: A0A0F7JQV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1309411:SY84 RS11490
gene id: 1309411:SY84_RS11490
uniprot id: A0A0F7JQI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1309411:SY84 RS05570
gene id: 1309411:SY84_RS05570
uniprot id: A0A0F7JKA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1309411:SY84 RS06520
gene id: 1309411:SY84_RS06520
uniprot id: A0A0F7JKL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1309411:SY84 RS02495
gene id: 1309411:SY84_RS02495
uniprot id: A0A0F7JMT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1309411:SY84 RS04245
gene id: 1309411:SY84_RS04245
uniprot id: A0A0F7JJS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1309411:SY84 RS10790
gene id: 1309411:SY84_RS10790
uniprot id: A0A0F7JUM4
names: Similarity
messages: Belongs to the peptidase S8 family.

1309411:SY84 RS11920
gene id: 1309411:SY84_RS11920
uniprot id: A0A0F7JQN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS07260
gene id: 1309411:SY84_RS07260
uniprot id: A0A0F7JQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1309411:SY84 RS04730
gene id: 1309411:SY84_RS04730
uniprot id: A0A0F7JNR4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1309411:SY84 RS06270
gene id: 1309411:SY84_RS06270
uniprot id: A0A0F7JM80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1309411:SY84 RS03505
gene id: 1309411:SY84_RS03505
uniprot id: A0A0F7JN55
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1309411:SY84 RS10730
gene id: 1309411:SY84_RS10730
uniprot id: A0A0F7JRM6
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1309411:SY84 RS10565
gene id: 1309411:SY84_RS10565
uniprot id: A0A0F7JM56
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1309411:SY84 RS13780
gene id: 1309411:SY84_RS13780
uniprot id: A0A0F7JRB3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1309411:SY84 RS04210
gene id: 1309411:SY84_RS04210
uniprot id: A0A0F7JP34
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1309411:SY84 RS03830
gene id: 1309411:SY84_RS03830
uniprot id: A0A0F7JLX7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1309411:SY84 RS13030
gene id: 1309411:SY84_RS13030
uniprot id: A0A0F7JR09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1309411:SY84 RS10840
gene id: 1309411:SY84_RS10840
uniprot id: A0A0F7JNX8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1309411:SY84 RS02665
gene id: 1309411:SY84_RS02665
uniprot id: A0A0F7JND6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1309411:SY84 RS05560
gene id: 1309411:SY84_RS05560
uniprot id: A0A0F7JML3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1309411:SY84 RS11660
gene id: 1309411:SY84_RS11660
uniprot id: A0A0F7JSB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS13775
gene id: 1309411:SY84_RS13775
uniprot id: A0A0F7JT25
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1309411:SY84 RS10820
gene id: 1309411:SY84_RS10820
uniprot id: A0A0F7JRQ9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1309411:SY84 RS04940
gene id: 1309411:SY84_RS04940
uniprot id: A0A0F7JLI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS12600
gene id: 1309411:SY84_RS12600
uniprot id: A0A0F7JMY2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1309411:SY84 RS08875
gene id: 1309411:SY84_RS08875
uniprot id: A0A0F7JQY5
names: Similarity
messages: Belongs to the FMO family.

1309411:SY84 RS04820
gene id: 1309411:SY84_RS04820
uniprot id: A0A0F7JM89
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1309411:SY84 RS01740
gene id: 1309411:SY84_RS01740
uniprot id: A0A0F7JKX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1309411:SY84 RS08340
gene id: 1309411:SY84_RS08340
uniprot id: A0A0F7JRA9
names: Similarity
messages: Belongs to the UPF0173 family.

1309411:SY84 RS12465
gene id: 1309411:SY84_RS12465
uniprot id: A0A0F7JSL1
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1309411:SY84 RS09695
gene id: 1309411:SY84_RS09695
uniprot id: A0A0F7JLV3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1309411:SY84 RS05480
gene id: 1309411:SY84_RS05480
uniprot id: A0A0F7JRL9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1309411:SY84 RS15325
gene id: 1309411:SY84_RS15325
uniprot id: A0A0F7JQY2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1309411:SY84 RS13215
gene id: 1309411:SY84_RS13215
uniprot id: A0A0F7JR56
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1309411:SY84 RS05675
gene id: 1309411:SY84_RS05675
uniprot id: A0A0F7JP91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1309411:SY84 RS05565
gene id: 1309411:SY84_RS05565
uniprot id: A0A0F7JQ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1309411:SY84 RS07780
gene id: 1309411:SY84_RS07780
uniprot id: A0A0F7JMM5
names: Similarity
messages: Belongs to the peptidase S9C family.

1309411:SY84 RS15535
gene id: 1309411:SY84_RS15535
uniprot id: A0A0F7JR10
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1309411:SY84 RS02210
gene id: 1309411:SY84_RS02210
uniprot id: A0A0F7JMH1
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS15395
gene id: 1309411:SY84_RS15395
uniprot id: A0A0F7JP40
names: Similarity
messages: Belongs to the lycopene cyclase family.

1309411:SY84 RS04795
gene id: 1309411:SY84_RS04795
uniprot id: A0A0F7JPG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS05125
gene id: 1309411:SY84_RS05125
uniprot id: A0A0F7JK65
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS10705
gene id: 1309411:SY84_RS10705
uniprot id: A0A0F7JQ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS00280
gene id: 1309411:SY84_RS00280
uniprot id: A0A0F7JUA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1309411:SY84 RS05095
gene id: 1309411:SY84_RS05095
uniprot id: A0A0F7JPD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1309411:SY84 RS12340
gene id: 1309411:SY84_RS12340
uniprot id: A0A0F7JQR9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1309411:SY84 RS04270
gene id: 1309411:SY84_RS04270
uniprot id: A0A0F7JJT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1309411:SY84 RS00515
gene id: 1309411:SY84_RS00515
uniprot id: A0A0F7JLF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1309411:SY84 RS12945
gene id: 1309411:SY84_RS12945
uniprot id: A0A0F7JT06
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1309411:SY84 RS14335
gene id: 1309411:SY84_RS14335
uniprot id: A0A0F7JRJ4
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1309411:SY84 RS07385
gene id: 1309411:SY84_RS07385
uniprot id: A0A0F7JKW5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS10120
gene id: 1309411:SY84_RS10120
uniprot id: A0A0F7JRB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1309411:SY84 RS09045
gene id: 1309411:SY84_RS09045
uniprot id: A0A0F7JPQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS02660
gene id: 1309411:SY84_RS02660
uniprot id: A0A0F7JLG5
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1309411:SY84 RS00230
gene id: 1309411:SY84_RS00230
uniprot id: A0A0F7JID5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1309411:SY84 RS11720
gene id: 1309411:SY84_RS11720
uniprot id: A0A0F7JPF2
names: Similarity
messages: Belongs to the SufE family.

1309411:SY84 RS13320
gene id: 1309411:SY84_RS13320
uniprot id: A0A0F7JR65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1309411:SY84 RS11870
gene id: 1309411:SY84_RS11870
uniprot id: A0A0F7JMQ7
names: Similarity
messages: Belongs to the FBPase class 2 family.

1309411:SY84 RS07545
gene id: 1309411:SY84_RS07545
uniprot id: A0A0F7JMK2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1309411:SY84 RS13985
gene id: 1309411:SY84_RS13985
uniprot id: A0A0F7JRD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS15055
gene id: 1309411:SY84_RS15055
uniprot id: A0A0F7JNZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1309411:SY84 RS15365
gene id: 1309411:SY84_RS15365
uniprot id: A0A0F7JTX9
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS05105
gene id: 1309411:SY84_RS05105
uniprot id: A0A0F7JLJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1309411:SY84 RS05695
gene id: 1309411:SY84_RS05695
uniprot id: A0A0F7JLU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1309411:SY84 RS14985
gene id: 1309411:SY84_RS14985
uniprot id: A0A0F7JNZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS01340
gene id: 1309411:SY84_RS01340
uniprot id: A0A0F7JJN8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1309411:SY84 RS03400
gene id: 1309411:SY84_RS03400
uniprot id: A0A0F7JNQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1309411:SY84 RS08320
gene id: 1309411:SY84_RS08320
uniprot id: A0A0F7JLF5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

1309411:SY84 RS08540
gene id: 1309411:SY84_RS08540
uniprot id: A0A0F7JLH5
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS05745
gene id: 1309411:SY84_RS05745
uniprot id: A0A0F7JKC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1309411:SY84 RS10965
gene id: 1309411:SY84_RS10965
uniprot id: A0A0F7JS58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS15145
gene id: 1309411:SY84_RS15145
uniprot id: A0A0F7JU11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1309411:SY84 RS06025
gene id: 1309411:SY84_RS06025
uniprot id: A0A0F7JQG0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1309411:SY84 RS09615
gene id: 1309411:SY84_RS09615
uniprot id: A0A0F7JNI4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

1309411:SY84 RS07705
gene id: 1309411:SY84_RS07705
uniprot id: A0A0F7JNW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1309411:SY84 RS14435
gene id: 1309411:SY84_RS14435
uniprot id: A0A0F7JTM8
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS06255
gene id: 1309411:SY84_RS06255
uniprot id: A0A0F7JN22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1309411:SY84 RS12040
gene id: 1309411:SY84_RS12040
uniprot id: A0A0F7JQP5
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS14215
gene id: 1309411:SY84_RS14215
uniprot id: A0A0F7JNG6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1309411:SY84 RS12655
gene id: 1309411:SY84_RS12655
uniprot id: A0A0F7JPP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1309411:SY84 RS07910
gene id: 1309411:SY84_RS07910
uniprot id: A0A0F7JL64
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1309411:SY84 RS10665
gene id: 1309411:SY84_RS10665
uniprot id: A0A0F7JNV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1309411:SY84 RS01755
gene id: 1309411:SY84_RS01755
uniprot id: A0A0F7JR70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1309411:SY84 RS13720
gene id: 1309411:SY84_RS13720
uniprot id: A0A0F7JT97
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS08155
gene id: 1309411:SY84_RS08155
uniprot id: A0A0F7JMS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

1309411:SY84 RS05680
gene id: 1309411:SY84_RS05680
uniprot id: A0A0F7JMP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1309411:SY84 RS04840
gene id: 1309411:SY84_RS04840
uniprot id: A0A0F7JNR8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1309411:SY84 RS05730
gene id: 1309411:SY84_RS05730
uniprot id: A0A0F7JP97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1309411:SY84 RS03915
gene id: 1309411:SY84_RS03915
uniprot id: A0A0F7JLY0
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1309411:SY84 RS05305
gene id: 1309411:SY84_RS05305
uniprot id: A0A0F7JLR7
names: Similarity
messages: Belongs to the fabD family.

1309411:SY84 RS12395
gene id: 1309411:SY84_RS12395
uniprot id: A0A0F7JMW9
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS00030
gene id: 1309411:SY84_RS00030
uniprot id: A0A0F7JJ53
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

1309411:SY84 RS15005
gene id: 1309411:SY84_RS15005
uniprot id: A0A0F7JSI3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1309411:SY84 RS11485
gene id: 1309411:SY84_RS11485
uniprot id: A0A0F7JS29
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1309411:SY84 RS04505
gene id: 1309411:SY84_RS04505
uniprot id: A0A0F7JNL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1309411:SY84 RS01355
gene id: 1309411:SY84_RS01355
uniprot id: A0A0F7JMN0
names: Similarity
messages: Belongs to the peptidase S41A family.

1309411:SY84 RS10530
gene id: 1309411:SY84_RS10530
uniprot id: A0A0F7JM53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1309411:SY84 RS14535
gene id: 1309411:SY84_RS14535
uniprot id: A0A0F7JTI0
names: Similarity
messages: Belongs to the thioredoxin family.

1309411:SY84 RS06020
gene id: 1309411:SY84_RS06020
uniprot id: A0A0F7JUG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1309411:SY84 RS07040
gene id: 1309411:SY84_RS07040
uniprot id: A0A0F7JNJ0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1309411:SY84 RS11875
gene id: 1309411:SY84_RS11875
uniprot id: A0A0F7JPF7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1309411:SY84 RS14790
gene id: 1309411:SY84_RS14790
uniprot id: A0A0F7JTU2
names: Similarity
messages: Belongs to the peptidase M29 family.

1309411:SY84 RS10535
gene id: 1309411:SY84_RS10535
uniprot id: A0A0F7JNU3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1309411:SY84 RS06545
gene id: 1309411:SY84_RS06545
uniprot id: A0A0F7JUG5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1309411:SY84 RS10295
gene id: 1309411:SY84_RS10295
uniprot id: A0A0F7JPW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS02455
gene id: 1309411:SY84_RS02455
uniprot id: A0A0F7JJ73
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1309411:SY84 RS05580
gene id: 1309411:SY84_RS05580
uniprot id: A0A0F7JP67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1309411:SY84 RS08565
gene id: 1309411:SY84_RS08565
uniprot id: A0A0F7JRC9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS15255
gene id: 1309411:SY84_RS15255
uniprot id: A0A0F7JTW9
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1309411:SY84 RS00145
gene id: 1309411:SY84_RS00145
uniprot id: A0A0F7JKB8
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1309411:SY84 RS05705
gene id: 1309411:SY84_RS05705
uniprot id: A0A0F7JMQ1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1309411:SY84 RS15630
gene id: 1309411:SY84_RS15630
uniprot id: A0A0F7JS83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS04620
gene id: 1309411:SY84_RS04620
uniprot id: A0A0F7JPC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1309411:SY84 RS07870
gene id: 1309411:SY84_RS07870
uniprot id: A0A0F7JQC5
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS06250
gene id: 1309411:SY84_RS06250
uniprot id: A0A0F7JPN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1309411:SY84 RS05790
gene id: 1309411:SY84_RS05790
uniprot id: A0A0F7JMR5
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1309411:SY84 RS10180
gene id: 1309411:SY84_RS10180
uniprot id: A0A0F7JRT0
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1309411:SY84 RS14490
gene id: 1309411:SY84_RS14490
uniprot id: A0A0F7JRQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1309411:SY84 RS08445
gene id: 1309411:SY84_RS08445
uniprot id: A0A0F7JN38
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1309411:SY84 RS00985
gene id: 1309411:SY84_RS00985
uniprot id: A0A0F7JJI5
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1309411:SY84 RS04490
gene id: 1309411:SY84_RS04490
uniprot id: A0A0F7JPA1
names: Similarity
messages: Belongs to the peptidase S1C family.

1309411:SY84 RS14480
gene id: 1309411:SY84_RS14480
uniprot id: A0A0F7JUZ8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1309411:SY84 RS14020
gene id: 1309411:SY84_RS14020
uniprot id: A0A0F7JTD7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1309411:SY84 RS14425
gene id: 1309411:SY84_RS14425
uniprot id: A0A0F7JNJ5
names: Cofactor
names: Similarity
messages: Belongs to the cytochrome b560 family.
messages: The heme is bound between the two transmembrane subunits.

1309411:SY84 RS13610
gene id: 1309411:SY84_RS13610
uniprot id: A0A0F7JQ28
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS02215
gene id: 1309411:SY84_RS02215
uniprot id: A0A0F7JL43
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1309411:SY84 RS12070
gene id: 1309411:SY84_RS12070
uniprot id: A0A0F7JSF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1309411:SY84 RS01090
gene id: 1309411:SY84_RS01090
uniprot id: A0A0F7JMH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1309411:SY84 RS07690
gene id: 1309411:SY84_RS07690
uniprot id: A0A0F7JML4
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS14685
gene id: 1309411:SY84_RS14685
uniprot id: A0A0F7JTJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1309411:SY84 RS00170
gene id: 1309411:SY84_RS00170
uniprot id: A0A0F7JJ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS08570
gene id: 1309411:SY84_RS08570
uniprot id: A0A0F7JLH7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1309411:SY84 RS09300
gene id: 1309411:SY84_RS09300
uniprot id: A0A0F7JR38
names: Similarity
messages: Belongs to the peptidase S1C family.

1309411:SY84 RS14910
gene id: 1309411:SY84_RS14910
uniprot id: A0A0F7JTP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1309411:SY84 RS06560
gene id: 1309411:SY84_RS06560
uniprot id: A0A0F7JPS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.
messages: Cytoplasm

1309411:SY84 RS05700
gene id: 1309411:SY84_RS05700
uniprot id: A0A0F7JP96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1309411:SY84 RS03515
gene id: 1309411:SY84_RS03515
uniprot id: A0A0F7JNT1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1309411:SY84 RS14465
gene id: 1309411:SY84_RS14465
uniprot id: A0A0F7JQF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS02805
gene id: 1309411:SY84_RS02805
uniprot id: A0A0F7JMZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1309411:SY84 RS01145
gene id: 1309411:SY84_RS01145
uniprot id: A0A0F7JKP3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1309411:SY84 RS03525
gene id: 1309411:SY84_RS03525
uniprot id: A0A0F7JJJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1309411:SY84 RS00175
gene id: 1309411:SY84_RS00175
uniprot id: A0A0F7JLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS10015
gene id: 1309411:SY84_RS10015
uniprot id: A0A0F7JLZ9
names: Similarity
messages: Belongs to the GSP E family.

1309411:SY84 RS13255
gene id: 1309411:SY84_RS13255
uniprot id: A0A0F7JR59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1309411:SY84 RS06160
gene id: 1309411:SY84_RS06160
uniprot id: A0A0F7JM60
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1309411:SY84 RS00400
gene id: 1309411:SY84_RS00400
uniprot id: A0A0F7JKF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

1309411:SY84 RS08575
gene id: 1309411:SY84_RS08575
uniprot id: A0A0F7JN48
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1309411:SY84 RS06540
gene id: 1309411:SY84_RS06540
uniprot id: A0A0F7JQK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1309411:SY84 RS10685
gene id: 1309411:SY84_RS10685
uniprot id: A0A0F7JS21
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS00285
gene id: 1309411:SY84_RS00285
uniprot id: A0A0F7JLE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1309411:SY84 RS04970
gene id: 1309411:SY84_RS04970
uniprot id: A0A0F7JK56
names: Similarity
messages: Belongs to the cytochrome P450 family.

1309411:SY84 RS15615
gene id: 1309411:SY84_RS15615
uniprot id: A0A0F7JP51
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1309411:SY84 RS10575
gene id: 1309411:SY84_RS10575
uniprot id: A0A0F7JRK8
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS11480
gene id: 1309411:SY84_RS11480
uniprot id: A0A0F7JS39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1309411:SY84 RS01085
gene id: 1309411:SY84_RS01085
uniprot id: A0A0F7JKN4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1309411:SY84 RS02435
gene id: 1309411:SY84_RS02435
uniprot id: A0A0F7JK79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1309411:SY84 RS07715
gene id: 1309411:SY84_RS07715
uniprot id: A0A0F7JL37
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1309411:SY84 RS09375
gene id: 1309411:SY84_RS09375
uniprot id: A0A0F7JLR0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1309411:SY84 RS02155
gene id: 1309411:SY84_RS02155
uniprot id: A0A0F7JL33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1309411:SY84 RS09150
gene id: 1309411:SY84_RS09150
uniprot id: A0A0F7JPI8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1309411:SY84 RS03275
gene id: 1309411:SY84_RS03275
uniprot id: A0A0F7JP94
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1309411:SY84 RS14975
gene id: 1309411:SY84_RS14975
uniprot id: A0A0F7JS11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1309411:SY84 RS04935
gene id: 1309411:SY84_RS04935
uniprot id: A0A0F7JK51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS15275
gene id: 1309411:SY84_RS15275
uniprot id: A0A0F7JU28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS03235
gene id: 1309411:SY84_RS03235
uniprot id: A0A0F7JKZ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1309411:SY84 RS14755
gene id: 1309411:SY84_RS14755
uniprot id: A0A0F7JQM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1309411:SY84 RS09935
gene id: 1309411:SY84_RS09935
uniprot id: A0A0F7JNL8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS04250
gene id: 1309411:SY84_RS04250
uniprot id: A0A0F7JL90
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1309411:SY84 RS10755
gene id: 1309411:SY84_RS10755
uniprot id: A0A0F7JNW4
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS11955
gene id: 1309411:SY84_RS11955
uniprot id: A0A0F7JSM6
names: Similarity
messages: Belongs to the peptidase S8 family.

1309411:SY84 RS01960
gene id: 1309411:SY84_RS01960
uniprot id: A0A0F7JL07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1309411:SY84 RS08775
gene id: 1309411:SY84_RS08775
uniprot id: A0A0F7JUZ7
names: Similarity
messages: Belongs to the TrpF family.

1309411:SY84 RS11935
gene id: 1309411:SY84_RS11935
uniprot id: A0A0F7JMR8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1309411:SY84 RS10760
gene id: 1309411:SY84_RS10760
uniprot id: A0A0F7JRQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1309411:SY84 RS01745
gene id: 1309411:SY84_RS01745
uniprot id: A0A0F7JMT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1309411:SY84 RS01165
gene id: 1309411:SY84_RS01165
uniprot id: A0A0F7JJL1
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS08420
gene id: 1309411:SY84_RS08420
uniprot id: A0A0F7JP99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1309411:SY84 RS13875
gene id: 1309411:SY84_RS13875
uniprot id: A0A0F7JRC3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1309411:SY84 RS13190
gene id: 1309411:SY84_RS13190
uniprot id: A0A0F7JR54
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1309411:SY84 RS11620
gene id: 1309411:SY84_RS11620
uniprot id: A0A0F7JSI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1309411:SY84 RS05535
gene id: 1309411:SY84_RS05535
uniprot id: A0A0F7JK97
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS07895
gene id: 1309411:SY84_RS07895
uniprot id: A0A0F7JQC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1309411:SY84 RS11055
gene id: 1309411:SY84_RS11055
uniprot id: A0A0F7JRW3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1309411:SY84 RS13550
gene id: 1309411:SY84_RS13550
uniprot id: A0A0F7JT87
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1309411:SY84 RS07145
gene id: 1309411:SY84_RS07145
uniprot id: A0A0F7JNK1
names: Similarity
messages: Belongs to the creatininase superfamily.

1309411:SY84 RS12760
gene id: 1309411:SY84_RS12760
uniprot id: A0A0F7JSP3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1309411:SY84 RS12840
gene id: 1309411:SY84_RS12840
uniprot id: A0A0F7JPS1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1309411:SY84 RS08635
gene id: 1309411:SY84_RS08635
uniprot id: A0A0F7JUZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1309411:SY84 RS13175
gene id: 1309411:SY84_RS13175
uniprot id: A0A0F7JN31
names: Similarity
messages: Belongs to the PGI/PMI family.

1309411:SY84 RS09025
gene id: 1309411:SY84_RS09025
uniprot id: A0A0F7JSS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1309411:SY84 RS09585
gene id: 1309411:SY84_RS09585
uniprot id: A0A0F7JR68
names: Similarity
messages: Belongs to the UbiD family.

1309411:SY84 RS13810
gene id: 1309411:SY84_RS13810
uniprot id: A0A0F7JT31
names: Similarity
messages: Belongs to the ComB family.

1309411:SY84 RS08925
gene id: 1309411:SY84_RS08925
uniprot id: A0A0F7JNA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1309411:SY84 RS12145
gene id: 1309411:SY84_RS12145
uniprot id: A0A0F7JSG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1309411:SY84 RS04535
gene id: 1309411:SY84_RS04535
uniprot id: A0A0F7JNL5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1309411:SY84 RS11030
gene id: 1309411:SY84_RS11030
uniprot id: A0A0F7JRV9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1309411:SY84 RS08965
gene id: 1309411:SY84_RS08965
uniprot id: A0A0F7JPH1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1309411:SY84 RS04050
gene id: 1309411:SY84_RS04050
uniprot id: A0A0F7JNB0
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS06190
gene id: 1309411:SY84_RS06190
uniprot id: A0A0F7JPL9
names: Similarity
messages: Belongs to the TelA family.

1309411:SY84 RS02420
gene id: 1309411:SY84_RS02420
uniprot id: A0A0F7JLC6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1309411:SY84 RS08285
gene id: 1309411:SY84_RS08285
uniprot id: A0A0F7JP64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1309411:SY84 RS14345
gene id: 1309411:SY84_RS14345
uniprot id: A0A0F7JNI3
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1309411:SY84 RS07615
gene id: 1309411:SY84_RS07615
uniprot id: A0A0F7JQ64
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1309411:SY84 RS05830
gene id: 1309411:SY84_RS05830
uniprot id: A0A0F7JLW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS00125
gene id: 1309411:SY84_RS00125
uniprot id: A0A0F7JIC8
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS06570
gene id: 1309411:SY84_RS06570
uniprot id: A0A0F7JQK3
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS03880
gene id: 1309411:SY84_RS03880
uniprot id: A0A0F7JN79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1309411:SY84 RS02395
gene id: 1309411:SY84_RS02395
uniprot id: A0A0F7JLC2
names: Similarity
messages: Belongs to the barstar family.

1309411:SY84 RS06345
gene id: 1309411:SY84_RS06345
uniprot id: A0A0F7JM85
names: Similarity
messages: Belongs to the peptidase S8 family.

1309411:SY84 RS08825
gene id: 1309411:SY84_RS08825
uniprot id: A0A0F7JQX7
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS09075
gene id: 1309411:SY84_RS09075
uniprot id: A0A0F7JPI1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1309411:SY84 RS07160
gene id: 1309411:SY84_RS07160
uniprot id: A0A0F7JMH9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1309411:SY84 RS06665
gene id: 1309411:SY84_RS06665
uniprot id: A0A0F7JUX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1309411:SY84 RS01390
gene id: 1309411:SY84_RS01390
uniprot id: A0A0F7JJP3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1309411:SY84 RS09355
gene id: 1309411:SY84_RS09355
uniprot id: A0A0F7JNE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1309411:SY84 RS05030
gene id: 1309411:SY84_RS05030
uniprot id: A0A0F7JPK3
names: Similarity
messages: Belongs to the asp23 family.

1309411:SY84 RS04860
gene id: 1309411:SY84_RS04860
uniprot id: A0A0F7JLG0
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1309411:SY84 RS09840
gene id: 1309411:SY84_RS09840
uniprot id: A0A0F7JLY1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1309411:SY84 RS03620
gene id: 1309411:SY84_RS03620
uniprot id: A0A0F7JJJ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1309411:SY84 RS09900
gene id: 1309411:SY84_RS09900
uniprot id: A0A0F7JR96
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1309411:SY84 RS13685
gene id: 1309411:SY84_RS13685
uniprot id: A0A0F7JNC9
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS12440
gene id: 1309411:SY84_RS12440
uniprot id: A0A0F7JQT2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Cytoplasm
messages: Homodimer.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1309411:SY84 RS06910
gene id: 1309411:SY84_RS06910
uniprot id: A0A0F7JKQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS05055
gene id: 1309411:SY84_RS05055
uniprot id: A0A0F7JMC9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1309411:SY84 RS13825
gene id: 1309411:SY84_RS13825
uniprot id: A0A0F7JTA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS12720
gene id: 1309411:SY84_RS12720
uniprot id: A0A0F7JMY8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1309411:SY84 RS00475
gene id: 1309411:SY84_RS00475
uniprot id: A0A0F7JIG2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1309411:SY84 RS04615
gene id: 1309411:SY84_RS04615
uniprot id: A0A0F7JM61
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1309411:SY84 RS15090
gene id: 1309411:SY84_RS15090
uniprot id: A0A0F7JQU8
names: Similarity
messages: Belongs to the peptidase S8 family.

1309411:SY84 RS09795
gene id: 1309411:SY84_RS09795
uniprot id: A0A0F7JRP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1309411:SY84 RS08625
gene id: 1309411:SY84_RS08625
uniprot id: A0A0F7JQV1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS00160
gene id: 1309411:SY84_RS00160
uniprot id: A0A0F7JP55
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1309411:SY84 RS08395
gene id: 1309411:SY84_RS08395
uniprot id: A0A0F7JLH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1309411:SY84 RS06765
gene id: 1309411:SY84_RS06765
uniprot id: A0A0F7JQL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS10510
gene id: 1309411:SY84_RS10510
uniprot id: A0A0F7JNT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1309411:SY84 RS09980
gene id: 1309411:SY84_RS09980
uniprot id: A0A0F7JRR2
names: Similarity
messages: Belongs to the DinB family.

1309411:SY84 RS02770
gene id: 1309411:SY84_RS02770
uniprot id: A0A0F7JKP0
names: Similarity
messages: Belongs to the leucine-binding protein family.

1309411:SY84 RS02840
gene id: 1309411:SY84_RS02840
uniprot id: A0A0F7JLK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1309411:SY84 RS00525
gene id: 1309411:SY84_RS00525
uniprot id: A0A0F7JM97
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1309411:SY84 RS14330
gene id: 1309411:SY84_RS14330
uniprot id: A0A0F7JTI2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1309411:SY84 RS04310
gene id: 1309411:SY84_RS04310
uniprot id: A0A0F7JM20
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS06650
gene id: 1309411:SY84_RS06650
uniprot id: A0A0F7JMB2
names: Similarity
messages: Belongs to the peptidase S33 family.

1309411:SY84 RS09500
gene id: 1309411:SY84_RS09500
uniprot id: A0A0F7JLT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1309411:SY84 RS00335
gene id: 1309411:SY84_RS00335
uniprot id: A0A0F7JJ86
names: Similarity
messages: Belongs to the peptidase C15 family.

1309411:SY84 RS00245
gene id: 1309411:SY84_RS00245
uniprot id: A0A0F7JKC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1309411:SY84 RS12845
gene id: 1309411:SY84_RS12845
uniprot id: A0A0F7JSQ8
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1309411:SY84 RS11925
gene id: 1309411:SY84_RS11925
uniprot id: A0A0F7JPW2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1309411:SY84 RS05765
gene id: 1309411:SY84_RS05765
uniprot id: A0A0F7JQB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1309411:SY84 RS02540
gene id: 1309411:SY84_RS02540
uniprot id: A0A0F7JNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1309411:SY84 RS14025
gene id: 1309411:SY84_RS14025
uniprot id: A0A0F7JNG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1309411:SY84 RS14055
gene id: 1309411:SY84_RS14055
uniprot id: A0A0F7JRF2
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS01130
gene id: 1309411:SY84_RS01130
uniprot id: A0A0F7JIM2
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS01270
gene id: 1309411:SY84_RS01270
uniprot id: A0A0F7JKR2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS08450
gene id: 1309411:SY84_RS08450
uniprot id: A0A0F7JQT3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1309411:SY84 RS14855
gene id: 1309411:SY84_RS14855
uniprot id: A0A0F7JTP5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1309411:SY84 RS14275
gene id: 1309411:SY84_RS14275
uniprot id: A0A0F7JTF8
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS06720
gene id: 1309411:SY84_RS06720
uniprot id: A0A0F7JMB9
names: Similarity
messages: Belongs to the DinB family.

1309411:SY84 RS15240
gene id: 1309411:SY84_RS15240
uniprot id: A0A0F7JS43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1309411:SY84 RS10700
gene id: 1309411:SY84_RS10700
uniprot id: A0A0F7JRM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1309411:SY84 RS13820
gene id: 1309411:SY84_RS13820
uniprot id: A0A0F7JRB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS10360
gene id: 1309411:SY84_RS10360
uniprot id: A0A0F7JNQ9
names: Similarity
messages: Belongs to the peptidase M16 family.

1309411:SY84 RS05815
gene id: 1309411:SY84_RS05815
uniprot id: A0A0F7JMR9
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS14145
gene id: 1309411:SY84_RS14145
uniprot id: A0A0F7JTE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

1309411:SY84 RS12530
gene id: 1309411:SY84_RS12530
uniprot id: A0A0F7JMX6
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS02750
gene id: 1309411:SY84_RS02750
uniprot id: A0A0F7JNE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1309411:SY84 RS11050
gene id: 1309411:SY84_RS11050
uniprot id: A0A0F7JP13
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

1309411:SY84 RS04640
gene id: 1309411:SY84_RS04640
uniprot id: A0A0F7JNQ3
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1309411:SY84 RS12805
gene id: 1309411:SY84_RS12805
uniprot id: A0A0F7JMZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1309411:SY84 RS16445
gene id: 1309411:SY84_RS16445
uniprot id: A0A0F7JQD0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

1309411:SY84 RS12080
gene id: 1309411:SY84_RS12080
uniprot id: A0A0F7JSP8
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS03215
gene id: 1309411:SY84_RS03215
uniprot id: A0A0F7JN33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1309411:SY84 RS00450
gene id: 1309411:SY84_RS00450
uniprot id: A0A0F7JJ98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1309411:SY84 RS08505
gene id: 1309411:SY84_RS08505
uniprot id: A0A0F7JN44
names: Similarity
messages: Belongs to the P(II) protein family.

1309411:SY84 RS04510
gene id: 1309411:SY84_RS04510
uniprot id: A0A0F7JM31
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1309411:SY84 RS09320
gene id: 1309411:SY84_RS09320
uniprot id: A0A0F7JND7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1309411:SY84 RS01375
gene id: 1309411:SY84_RS01375
uniprot id: A0A0F7JKS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1309411:SY84 RS05300
gene id: 1309411:SY84_RS05300
uniprot id: A0A0F7JK89
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1309411:SY84 RS13670
gene id: 1309411:SY84_RS13670
uniprot id: A0A0F7JT12
names: Similarity
messages: Belongs to the ycf81 family.

1309411:SY84 RS06770
gene id: 1309411:SY84_RS06770
uniprot id: A0A0F7JKN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1309411:SY84 RS07865
gene id: 1309411:SY84_RS07865
uniprot id: A0A0F7JMN4
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS13435
gene id: 1309411:SY84_RS13435
uniprot id: A0A0F7JT77
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS04185
gene id: 1309411:SY84_RS04185
uniprot id: A0A0F7JP27
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1309411:SY84 RS04685
gene id: 1309411:SY84_RS04685
uniprot id: A0A0F7JLC5
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1309411:SY84 RS07190
gene id: 1309411:SY84_RS07190
uniprot id: A0A0F7JMI0
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1309411:SY84 RS10940
gene id: 1309411:SY84_RS10940
uniprot id: A0A0F7JS53
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS12150
gene id: 1309411:SY84_RS12150
uniprot id: A0A0F7JQQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1309411:SY84 RS12910
gene id: 1309411:SY84_RS12910
uniprot id: A0A0F7JT01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1309411:SY84 RS00885
gene id: 1309411:SY84_RS00885
uniprot id: A0A0F7JU45
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1309411:SY84 RS06245
gene id: 1309411:SY84_RS06245
uniprot id: A0A0F7JPH6
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS11305
gene id: 1309411:SY84_RS11305
uniprot id: A0A0F7JMG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

1309411:SY84 RS11150
gene id: 1309411:SY84_RS11150
uniprot id: A0A0F7JS77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1309411:SY84 RS15300
gene id: 1309411:SY84_RS15300
uniprot id: A0A0F7JQX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS00470
gene id: 1309411:SY84_RS00470
uniprot id: A0A0F7JM76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1309411:SY84 RS03945
gene id: 1309411:SY84_RS03945
uniprot id: A0A0F7JSG0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1309411:SY84 RS01150
gene id: 1309411:SY84_RS01150
uniprot id: A0A0F7JMJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS01365
gene id: 1309411:SY84_RS01365
uniprot id: A0A0F7JJP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

1309411:SY84 RS12855
gene id: 1309411:SY84_RS12855
uniprot id: A0A0F7JSZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1309411:SY84 RS04760
gene id: 1309411:SY84_RS04760
uniprot id: A0A0F7JNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS05195
gene id: 1309411:SY84_RS05195
uniprot id: A0A0F7JMF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1309411:SY84 RS11460
gene id: 1309411:SY84_RS11460
uniprot id: A0A0F7JQI1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1309411:SY84 RS10145
gene id: 1309411:SY84_RS10145
uniprot id: A0A0F7JRC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1309411:SY84 RS11350
gene id: 1309411:SY84_RS11350
uniprot id: A0A0F7JQG6
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1309411:SY84 RS05850
gene id: 1309411:SY84_RS05850
uniprot id: A0A0F7JKD5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1309411:SY84 RS03885
gene id: 1309411:SY84_RS03885
uniprot id: A0A0F7JLX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS12990
gene id: 1309411:SY84_RS12990
uniprot id: A0A0F7JN12
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1309411:SY84 RS05750
gene id: 1309411:SY84_RS05750
uniprot id: A0A0F7JLV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1309411:SY84 RS14600
gene id: 1309411:SY84_RS14600
uniprot id: A0A0F7JNM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS12155
gene id: 1309411:SY84_RS12155
uniprot id: A0A0F7JSQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1309411:SY84 RS00925
gene id: 1309411:SY84_RS00925
uniprot id: A0A0F7JIJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1309411:SY84 RS06235
gene id: 1309411:SY84_RS06235
uniprot id: A0A0F7JKH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1309411:SY84 RS01350
gene id: 1309411:SY84_RS01350
uniprot id: A0A0F7JKS4
names: Similarity
messages: Belongs to the peptidase S1C family.

1309411:SY84 RS13160
gene id: 1309411:SY84_RS13160
uniprot id: A0A0F7JTC0
names: Similarity
messages: Belongs to the FUN14 family.

1309411:SY84 RS12725
gene id: 1309411:SY84_RS12725
uniprot id: A0A0F7JPQ5
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1309411:SY84 RS08470
gene id: 1309411:SY84_RS08470
uniprot id: A0A0F7JN42
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1309411:SY84 RS08475
gene id: 1309411:SY84_RS08475
uniprot id: A0A0F7JPN2
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS09550
gene id: 1309411:SY84_RS09550
uniprot id: A0A0F7JR66
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

1309411:SY84 RS14980
gene id: 1309411:SY84_RS14980
uniprot id: A0A0F7JTQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1309411:SY84 RS09365
gene id: 1309411:SY84_RS09365
uniprot id: A0A0F7JPL7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1309411:SY84 RS01840
gene id: 1309411:SY84_RS01840
uniprot id: A0A0F7JSC2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1309411:SY84 RS07185
gene id: 1309411:SY84_RS07185
uniprot id: A0A0F7JKT9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-66 and Arg-69) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1309411:SY84 RS15400
gene id: 1309411:SY84_RS15400
uniprot id: A0A0F7JQZ4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1309411:SY84 RS01440
gene id: 1309411:SY84_RS01440
uniprot id: A0A0F7JMN8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1309411:SY84 RS04120
gene id: 1309411:SY84_RS04120
uniprot id: A0A0F7JNC0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1309411:SY84 RS01405
gene id: 1309411:SY84_RS01405
uniprot id: A0A0F7JKT2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1309411:SY84 RS12280
gene id: 1309411:SY84_RS12280
uniprot id: A0A0F7JPK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1309411:SY84 RS15510
gene id: 1309411:SY84_RS15510
uniprot id: A0A0F7JVF7
names: Cofactor
messages: Can also use Mn(2+) ion.

1309411:SY84 RS14175
gene id: 1309411:SY84_RS14175
uniprot id: A0A0F7JRH4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1309411:SY84 RS05085
gene id: 1309411:SY84_RS05085
uniprot id: A0A0F7JMD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

1309411:SY84 RS11035
gene id: 1309411:SY84_RS11035
uniprot id: A0A0F7JQ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1309411:SY84 RS13920
gene id: 1309411:SY84_RS13920
uniprot id: A0A0F7JNF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1309411:SY84 RS06565
gene id: 1309411:SY84_RS06565
uniprot id: A0A0F7JN83
names: Subcellular Location Annotation
messages: Membrane

1309411:SY84 RS12565
gene id: 1309411:SY84_RS12565
uniprot id: A0A0F7JPP0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1309411:SY84 RS01770
gene id: 1309411:SY84_RS01770
uniprot id: A0A0F7JM78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1309411:SY84 RS00895
gene id: 1309411:SY84_RS00895
uniprot id: A0A0F7JME9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1309411:SY84 RS15100
gene id: 1309411:SY84_RS15100
uniprot id: A0A0F7JS25
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1309411:SY84 RS03365
gene id: 1309411:SY84_RS03365
uniprot id: A0A0F7JNQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1309411:SY84 RS04085
gene id: 1309411:SY84_RS04085
uniprot id: A0A0F7JM00
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1309411:SY84 RS14010
gene id: 1309411:SY84_RS14010
uniprot id: A0A0F7JT90
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1309411:SY84 RS05575
gene id: 1309411:SY84_RS05575
uniprot id: A0A0F7JLS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1309411:SY84 RS02095
gene id: 1309411:SY84_RS02095
uniprot id: A0A0F7JMX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1309411:SY84 RS05495
gene id: 1309411:SY84_RS05495
uniprot id: A0A0F7JMK9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1309411:SY84 RS12645
gene id: 1309411:SY84_RS12645
uniprot id: A0A0F7JSX2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1309411:SY84 RS04645
gene id: 1309411:SY84_RS04645
uniprot id: A0A0F7JM65
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1309411:SY84 RS00565
gene id: 1309411:SY84_RS00565
uniprot id: A0A0F7JMA2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1309411:SY84 RS14550
gene id: 1309411:SY84_RS14550
uniprot id: A0A0F7JTR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1309411:SY84 RS07710
gene id: 1309411:SY84_RS07710
uniprot id: A0A0F7JQY7
names: Similarity
messages: Belongs to the SCO1/2 family.

1309411:SY84 RS09580
gene id: 1309411:SY84_RS09580
uniprot id: A0A0F7JNI0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1309411:SY84 RS06945
gene id: 1309411:SY84_RS06945
uniprot id: A0A0F7JPW9
names: Similarity
messages: Belongs to the glutamate synthase family.

1309411:SY84 RS02815
gene id: 1309411:SY84_RS02815
uniprot id: A0A0F7JLK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1309411:SY84 RS01415
gene id: 1309411:SY84_RS01415
uniprot id: A0A0F7JIT3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1309411:SY84 RS12130
gene id: 1309411:SY84_RS12130
uniprot id: A0A0F7JMU5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA.

1309411:SY84 RS05710
gene id: 1309411:SY84_RS05710
uniprot id: A0A0F7JQA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1309411:SY84 RS10500
gene id: 1309411:SY84_RS10500
uniprot id: A0A0F7JM52
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1309411:SY84 RS01160
gene id: 1309411:SY84_RS01160
uniprot id: A0A0F7JIM6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1309411:SY84 RS10745
gene id: 1309411:SY84_RS10745
uniprot id: A0A0F7JS27
names: Similarity
messages: Belongs to the RutC family.

1309411:SY84 RS07620
gene id: 1309411:SY84_RS07620
uniprot id: A0A0F7JNU8
names: Similarity
messages: Belongs to the peptidase S66 family.

1309411:SY84 RS02695
gene id: 1309411:SY84_RS02695
uniprot id: A0A0F7JLG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1309411:SY84 RS06040
gene id: 1309411:SY84_RS06040
uniprot id: A0A0F7JPG2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.